BLASTX 7.6.2

Query= UN17197 /QuerySize=1289
        (1288 letters)

Database: UniProt/SwissProt;
          518,415 sequences; 182,829,261 total letters
                                                                  Score    E
Sequences producing significant alignments:                       (bits) Value

sp|Q5JPI9|MTL10_HUMAN Methyltransferase-like protein 10 OS=Homo ...    110   3e-023
sp|Q5D013|MTL10_DANRE Methyltransferase-like protein 10 OS=Danio...    106   4e-022
sp|Q9D853|MTL10_MOUSE Methyltransferase-like protein 10 OS=Mus m...    106   6e-022
sp|P40516|YIG4_YEAST Uncharacterized methyltransferase YIL064W O...     83   3e-015
sp|Q9P7Z3|YHRE_SCHPO Uncharacterized protein C839.14c OS=Schizos...     66   6e-010

>sp|Q5JPI9|MTL10_HUMAN Methyltransferase-like protein 10 OS=Homo sapiens
        GN=METTL10 PE=1 SV=2

          Length = 291

 Score =  110 bits (274), Expect = 3e-023
 Identities = 56/121 (46%), Positives = 84/121 (69%), Gaps = 2/121 (1%)
 Frame = -2

Query: 738 NVLDLGTGNGLLLHQLAKEGFSDLTGTDYSEGAVELAQNLSQRDGFPNIRFMVDDILDTK 559
           +VLD+GTGNG+ L +LAK GFS++TG DYS  A++L+ ++ +++G  NI+  V+D L+  
Sbjct:  82 SVLDIGTGNGVFLVELAKFGFSNITGIDYSPSAIQLSGSIIEKEGLSNIKLKVEDFLNLS 141

Query: 558 LERQ-FKLVMDKGTLDAIGLHPDGPV-KRVMYWDSVSKLVAPGGILVITSCNNTKDELLE 385
            +   F + +DKGT DAI L+PD  + KR  Y  S+S+++   G  +ITSCN TK+ELL 
Sbjct: 142 TQLSGFHICIDKGTFDAISLNPDNAIEKRKQYVKSLSRVLKVKGFFLITSCNWTKEELLN 201

Query: 384 E 382
           E
Sbjct: 202 E 202

>sp|Q5D013|MTL10_DANRE Methyltransferase-like protein 10 OS=Danio rerio
        GN=mettl10 PE=2 SV=1

          Length = 233

 Score =  106 bits (264), Expect = 4e-022
 Identities = 55/119 (46%), Positives = 78/119 (65%), Gaps = 2/119 (1%)
 Frame = -2

Query: 735 VLDLGTGNGLLLHQLAKEGFSDLTGTDYSEGAVELAQNLSQRDGFPNIRFMVDDILDTKL 556
           +LD+GTGNG+ L +LA+ GFS+LTG DYS+ A+EL  N+   +G  NI   V+D L+   
Sbjct:  79 ILDIGTGNGMFLVELARHGFSNLTGIDYSKAALELTTNILVEEGLKNINIQVEDFLNPST 138

Query: 555 E-RQFKLVMDKGTLDAIGLHP-DGPVKRVMYWDSVSKLVAPGGILVITSCNNTKDELLE 385
           E + F + +DKGT DAI L+P D    +  Y  S+  ++ P G  +ITSCN TK++LLE
Sbjct: 139 ELKGFDVCIDKGTFDAISLNPEDREEAKKHYVTSLRAVMRPNGFFIITSCNWTKEQLLE 197

>sp|Q9D853|MTL10_MOUSE Methyltransferase-like protein 10 OS=Mus musculus
        GN=Mettl10 PE=2 SV=1

          Length = 244

 Score =  106 bits (262), Expect = 6e-022
 Identities = 63/145 (43%), Positives = 91/145 (62%), Gaps = 5/145 (3%)
 Frame = -2

Query: 738 NVLDLGTGNGLLLHQLAKEGFSDLTGTDYSEGAVELAQNLSQRDGFPNIRFMVDDILD-- 565
           +VLD+GTGNG+ L +L K GFS++TG DYS  A++L+ ++ +++G  NI   V+D L+  
Sbjct:  82 SVLDIGTGNGVFLVELVKHGFSNITGIDYSPSAIKLSASILEKEGLSNINLKVEDFLNPS 141

Query: 564 TKLERQFKLVMDKGTLDAIGLHPDGPV-KRVMYWDSVSKLVAPGGILVITSCNNTKDELL 388
           TKL   F + +DKGT DAI L+PD  + KR  Y  S+S+++   G  +ITSCN TK ELL
Sbjct: 142 TKLS-GFHVCVDKGTYDAISLNPDNAIEKRKQYVMSLSRVLEVKGFFLITSCNWTKAELL 200

Query: 387 EEV-ENFNMRKSNLTGDVSSEAASG 316
           +   E F + +   T   S    SG
Sbjct: 201 DAFSEGFELFEELPTPKFSFGGRSG 225

>sp|P40516|YIG4_YEAST Uncharacterized methyltransferase YIL064W OS=Saccharomyces
        cerevisiae GN=YIL064W PE=1 SV=1

          Length = 257

 Score =  83 bits (204), Expect = 3e-015
 Identities = 54/133 (40%), Positives = 83/133 (62%), Gaps = 7/133 (5%)
 Frame = -2

Query: 738 NVLDLGTGNGLLLHQLAKEGF-SDLTGTDYSEGAVELAQNLSQRDGFPN-IRFMVDDILD 565
           +V+DLGTGNG +L +L +  F   L G DYSE +V+LA N+++  G  N I F   DI  
Sbjct:  96 SVVDLGTGNGHMLFELHQTEFQGKLVGIDYSEESVKLASNIAEATGVDNFISFQQADIFS 155

Query: 564 TKLE-RQFKLVMDKGTLDAI---GLHPDGPVKRV-MYWDSVSKLVAPGGILVITSCNNTK 400
              +  ++ +V+DKGTLDAI   G+  +G +  V +Y   V +++   GI +ITSCN T+
Sbjct: 156 GDWKPGKYDIVLDKGTLDAISLSGMKINGKLDVVDVYAGVVERILKKDGIFLITSCNFTQ 215

Query: 399 DELLEEVENFNMR 361
           DEL++ +E  N++
Sbjct: 216 DELVKIIETDNLK 228

>sp|Q9P7Z3|YHRE_SCHPO Uncharacterized protein C839.14c OS=Schizosaccharomyces
        pombe GN=SPBC839.14c PE=2 SV=1

          Length = 238

 Score =  66 bits (159), Expect = 6e-010
 Identities = 42/101 (41%), Positives = 61/101 (60%), Gaps = 6/101 (5%)
 Frame = -2

Query: 669 LTGTDYSEGAVELAQNLSQRDGFPN-IRF-MVDDILDTKL-ERQFKLVMDKGTLDAIGLH 499
           L G DYSE A+ LA+N+++   F + ++F  +D I D+K   + + L++DKGT DAI L 
Sbjct:  96 LVGVDYSEAAIVLAKNIARHRQFSDKVKFQQLDIIKDSKFCSKDWDLILDKGTFDAISLS 155

Query: 498 P---DGPVKRVMYWDSVSKLVAPGGILVITSCNNTKDELLE 385
               DG     +Y D V  +++P GI +ITSCN T  EL E
Sbjct: 156 GELLDGRPLNSVYVDRVRGMLSPNGIFLITSCNWTIQELEE 196


 Score =  54 bits (127), Expect = 3e-006
 Identities = 21/46 (45%), Positives = 28/46 (60%)
 Frame = -2

Query: 963 QSMLGLQSYWDAAYSDELSNFREHGHTGEVWFGDDVMEIVTSWTKD 826
           +S LG + YWD  Y  E+SNF E    GEVWFG++  E +  W +D
Sbjct:   6 ESKLGTKQYWDNVYEREVSNFTEFNDEGEVWFGEEAEERIVQWLED 51

  Database: UniProt/SwissProt
    Posted date:  Sat Aug 07 14:36:18 2010
  Number of letters in database: 182,829,261
  Number of sequences in database:  518,415

Lambda     K     H
   0.267   0.041    0.140
Gapped
Lambda     K     H
   0.267   0.041    0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,472,851,095
Number of Sequences: 518415
Number of Extensions: 69472851095
Number of Successful Extensions: 496854919
Number of sequences better than 0.0: 0