BLASTX 7.6.2
Query= UN17346 /QuerySize=1244
(1243 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53611|PGTB2_HUMAN Geranylgeranyl transferase type-2 subunit ... 408 6e-113
sp|Q5E9B3|PGTB2_BOVIN Geranylgeranyl transferase type-2 subunit ... 405 5e-112
sp|Q08603|PGTB2_RAT Geranylgeranyl transferase type-2 subunit be... 402 3e-111
sp|B0G172|PGTB2_DICDI Probable geranylgeranyl transferase type-2... 396 3e-109
sp|P53612|PGTB2_MOUSE Geranylgeranyl transferase type-2 subunit ... 391 6e-108
sp|P20133|PGTB2_YEAST Geranylgeranyl transferase type-2 subunit ... 339 4e-092
sp|P46960|PGTB2_SCHPO Geranylgeranyl transferase type-2 subunit ... 334 8e-091
sp|P41992|GGTB2_CAEEL Probable geranylgeranyl transferase type-2... 311 7e-084
sp|O93830|PGTB2_CANAL Geranylgeranyl transferase type-2 subunit ... 295 5e-079
sp|O13782|FNTB_SCHPO Protein farnesyltransferase subunit beta OS... 134 2e-030
sp|P49356|FNTB_HUMAN Protein farnesyltransferase subunit beta OS... 131 1e-029
sp|Q8K2I1|FNTB_MOUSE Protein farnesyltransferase subunit beta OS... 129 5e-029
sp|Q02293|FNTB_RAT Protein farnesyltransferase subunit beta OS=R... 129 5e-029
sp|P49355|FNTB_BOVIN Protein farnesyltransferase subunit beta OS... 129 7e-029
sp|Q55D51|FNTB_DICDI Protein farnesyltransferase subunit beta OS... 123 4e-027
sp|P53610|PGTB1_RAT Geranylgeranyl transferase type-1 subunit be... 122 5e-027
sp|P53609|PGTB1_HUMAN Geranylgeranyl transferase type-1 subunit ... 122 6e-027
sp|Q8BUY9|PGTB1_MOUSE Geranylgeranyl transferase type-1 subunit ... 122 6e-027
sp|Q5EAD5|PGTB1_BOVIN Geranylgeranyl transferase type-1 subunit ... 121 1e-026
sp|Q55DA3|PGTB1_DICDI Geranylgeranyl transferase type-1 subunit ... 119 5e-026
>sp|P53611|PGTB2_HUMAN Geranylgeranyl transferase type-2 subunit beta OS=Homo
sapiens GN=RABGGTB PE=1 SV=2
Length = 331
Score = 408 bits (1047), Expect = 6e-113
Identities = 179/306 (58%), Positives = 239/306 (78%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLMT 981
L+ +KH YI KK+ +E + ++LRM+G YWGLT +DL+ +L ++ +E+++++ +
Sbjct: 18 LLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKS 77
Query: 980 CQHESGGFAGNTGHDPHVLYTLSAVQILALFDKLDILDVAKVSSYIAGLQNEDGSFSGDM 801
CQHE GG + + GHDPH+LYTLSAVQIL L+D ++++DV KV Y+ GLQ EDGSF+GD+
Sbjct: 78 CQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDI 137
Query: 800 WGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCC 621
WGE+DTRFS+ A+ L++L LD INVEKA+++++SC N DGGFGC PG+ESHAGQI+CC
Sbjct: 138 WGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCC 197
Query: 620 VGALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHW 441
G LAIT LH V+ DLLGWWLCERQ+ SGGLNGRPEKLPDVCYSWWVL+SL +I R+HW
Sbjct: 198 TGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHW 257
Query: 440 INKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPAYALPV 261
I++ KL FIL CQD E GG +DRP D VD FHT FG+AGLSLL +KP++P + +P
Sbjct: 258 IDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPE 317
Query: 260 DVINRI 243
+V+ R+
Sbjct: 318 EVLQRV 323
>sp|Q5E9B3|PGTB2_BOVIN Geranylgeranyl transferase type-2 subunit beta OS=Bos
taurus GN=RABGGTB PE=2 SV=1
Length = 331
Score = 405 bits (1039), Expect = 5e-112
Identities = 177/306 (57%), Positives = 237/306 (77%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLMT 981
L+ +KH YI KK+ +E + ++LRM+G YWGLT +DL+ +L ++ +E+++++ +
Sbjct: 18 LLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILTFIKS 77
Query: 980 CQHESGGFAGNTGHDPHVLYTLSAVQILALFDKLDILDVAKVSSYIAGLQNEDGSFSGDM 801
CQHE GG + + GHDPH+LYTLSAVQIL L+D ++++D+ KV Y+ LQ EDGSF+GD+
Sbjct: 78 CQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDINKVVEYVQSLQKEDGSFAGDI 137
Query: 800 WGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCC 621
WGE+DTRFS+ A+ L++L LD INVEKA+++++SC N DGGFGC PG+ESHAGQI+CC
Sbjct: 138 WGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCC 197
Query: 620 VGALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHW 441
G LAIT LH V+ DLLGWWLCERQ+ SGGLNGRPEKLPDVCYSWWVL+SL +I R+HW
Sbjct: 198 TGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHW 257
Query: 440 INKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPAYALPV 261
I++ KL FIL CQD E GG +DRP D VD FHT FG+AGLSLL +KP+ P + +P
Sbjct: 258 IDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPE 317
Query: 260 DVINRI 243
+V+ R+
Sbjct: 318 EVLRRV 323
>sp|Q08603|PGTB2_RAT Geranylgeranyl transferase type-2 subunit beta OS=Rattus
norvegicus GN=Rabggtb PE=1 SV=1
Length = 331
Score = 402 bits (1032), Expect = 3e-111
Identities = 177/306 (57%), Positives = 236/306 (77%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLMT 981
L+ +KH YI KK+ +E + ++LRM+G YWGLT +DL+ +L ++ +E++ ++ +
Sbjct: 18 LLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKS 77
Query: 980 CQHESGGFAGNTGHDPHVLYTLSAVQILALFDKLDILDVAKVSSYIAGLQNEDGSFSGDM 801
CQHE GG + + GHDPH+LYTLSAVQIL L+D + +++V KV +Y+ LQ EDGSF+GD+
Sbjct: 78 CQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDI 137
Query: 800 WGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCC 621
WGE+DTRFS+ A+ L++L LD INVEKA+++++SC N DGGFGC PG+ESHAGQI+CC
Sbjct: 138 WGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCC 197
Query: 620 VGALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHW 441
G LAIT LH V+ DLLGWWLCERQ+ SGGLNGRPEKLPDVCYSWWVL+SL +I R+HW
Sbjct: 198 TGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHW 257
Query: 440 INKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPAYALPV 261
I++ KL FIL CQD E GG +DRP D VD FHT FG+AGLSLL +KP+ P + +P
Sbjct: 258 IDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPE 317
Query: 260 DVINRI 243
+V+ R+
Sbjct: 318 EVLQRV 323
>sp|B0G172|PGTB2_DICDI Probable geranylgeranyl transferase type-2 subunit beta
OS=Dictyostelium discoideum GN=rabggtb PE=3 SV=1
Length = 339
Score = 396 bits (1015), Expect = 3e-109
Identities = 186/323 (57%), Positives = 235/323 (72%), Gaps = 2/323 (0%)
Frame = -3
Query: 1205 KLMSSSSSSSSQMGELVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDK 1026
K ++++++ L+ DKHV YI+ KK+SFE V +H+RMNG YWGL++L LL
Sbjct: 7 KESTTTTTTIDHTTNLLIDKHVEYIVKLGSKKDSFEYWVTEHIRMNGMYWGLSSLYLLKS 66
Query: 1025 LPSVSVDEVVSWLMTCQHESGGFAGNTGHDPHVLYTLSAVQILALFDKLDILDVAKVSSY 846
L + +EV+ WL++CQ +GGF GNT HD H+L TLSAVQIL +D LD +D+ V Y
Sbjct: 67 LDKLDKNEVIQWLLSCQKSNGGFGGNTSHDDHLLSTLSAVQILIQYDALDKIDINSVVDY 126
Query: 845 IAGLQNEDGSFSGDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFG 666
+ LQ EDGSF GD WGEVDTRFSY AI CLS+LK LDKIN EKAV+YI+SC+N DGGFG
Sbjct: 127 VVKLQREDGSFVGDQWGEVDTRFSYAAIMCLSLLKSLDKINCEKAVEYILSCQNFDGGFG 186
Query: 665 CTPGAESHAGQIFCCVGALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYS 486
PGAESHAGQIF CVGAL+I ++ +D D LGWWL ERQ+ +GGLNGRPEK DVCYS
Sbjct: 187 SIPGAESHAGQIFTCVGALSILNEINKIDIDKLGWWLSERQLPNGGLNGRPEKSSDVCYS 246
Query: 485 WWVLSSLIMIDRVHWINKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLE 306
WWVLS+L IDR+HWI+ KL +IL CQD E GGI+D+P D D+FHT+FG+ GLSL+
Sbjct: 247 WWVLSALSAIDRLHWIDNDKLKSYILKCQDNETGGIADKPGDIPDVFHTFFGICGLSLMG 306
Query: 305 Y--PGVKPIDPAYALPVDVINRI 243
Y ++ IDP YAL + ++
Sbjct: 307 YFKDQIESIDPVYALGTKTLQKL 329
>sp|P53612|PGTB2_MOUSE Geranylgeranyl transferase type-2 subunit beta OS=Mus
musculus GN=Rabggtb PE=2 SV=1
Length = 339
Score = 391 bits (1004), Expect = 6e-108
Identities = 174/306 (56%), Positives = 231/306 (75%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLMT 981
L+ +KH YI KK+ +E + ++LRM+G YWGLT +DL+ +L ++ +E++ ++ +
Sbjct: 26 LLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNREEILVFIKS 85
Query: 980 CQHESGGFAGNTGHDPHVLYTLSAVQILALFDKLDILDVAKVSSYIAGLQNEDGSFSGDM 801
CQHE GG + + GHDPH+LYTLSAVQIL L+D + +++V KV +Y+ LQ EDGSF+GD+
Sbjct: 86 CQHECGGISASIGHDPHLLYTLSAVQILTLYDSVHVINVDKVVAYVQSLQKEDGSFAGDI 145
Query: 800 WGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCC 621
WGE+DTRFS+ A+ L++L LD INVEKA+++++SC N DGGFGC PG+ESHAGQI+CC
Sbjct: 146 WGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCC 205
Query: 620 VGALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHW 441
G LAIT LH V+ DLLGWWLCE Q+ SG LNGR EKLPDVCYSWWVL+SL +I R+HW
Sbjct: 206 TGFLAITSQLHQVNSDLLGWWLCEAQLPSGALNGRREKLPDVCYSWWVLASLKIIGRLHW 265
Query: 440 INKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPAYALPV 261
I KL FIL CQD E GG +DRP D VD FHT FG+AGLSLL +KP+ P + +P
Sbjct: 266 IVSEKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPE 325
Query: 260 DVINRI 243
+V+ R+
Sbjct: 326 EVLQRV 331
>sp|P20133|PGTB2_YEAST Geranylgeranyl transferase type-2 subunit beta
OS=Saccharomyces cerevisiae GN=BET2 PE=1 SV=3
Length = 325
Score = 339 bits (867), Expect = 4e-092
Identities = 171/312 (54%), Positives = 215/312 (68%), Gaps = 7/312 (2%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLMT 981
L+ +KH+RYI + KK +FE + +HLR+NG YWGLT L +LD + +EV+S++++
Sbjct: 7 LLKEKHIRYIESLDTKKHNFEYWLTEHLRLNGIYWGLTALCVLDSPETFVKEEVISFVLS 66
Query: 980 CQHES-GGFAGNTGHDPHVLYTLSAVQILALFDKLDILD---VAKVSSYIAGLQNEDGSF 813
C + G FA HD H+L TLSAVQILA +D LD+L ++ S+I G Q EDGSF
Sbjct: 67 CWDDKYGAFAPFPRHDAHLLTTLSAVQILATYDALDVLGKDRKVRLISFIRGNQLEDGSF 126
Query: 812 SGDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQ 633
GD +GEVDTRF Y A+ LSIL L V+ AVD+++ C N DGGFG P AESHA Q
Sbjct: 127 QGDRFGEVDTRFVYTALSALSILGELTSEVVDPAVDFVLKCYNFDGGFGLCPNAESHAAQ 186
Query: 632 IFCCVGALAITGSLHHVDKDLL---GWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLI 462
F C+GALAI L + D L GWWLCERQ+ GGLNGRP KLPDVCYSWWVLSSL
Sbjct: 187 AFTCLGALAIANKLDMLSDDQLEEIGWWLCERQLPEGGLNGRPSKLPDVCYSWWVLSSLA 246
Query: 461 MIDRVHWINKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPID 282
+I R+ WIN KL +FIL CQD + GGISDRP++ VD+FHT FGVAGLSL+ Y + PID
Sbjct: 247 IIGRLDWINYEKLTEFILKCQDEKKGGISDRPENEVDVFHTVFGVAGLSLMGYDNLVPID 306
Query: 281 PAYALPVDVINR 246
P Y +P V ++
Sbjct: 307 PIYCMPKSVTSK 318
>sp|P46960|PGTB2_SCHPO Geranylgeranyl transferase type-2 subunit beta
OS=Schizosaccharomyces pombe GN=ptb1 PE=2 SV=1
Length = 311
Score = 334 bits (856), Expect = 8e-091
Identities = 151/311 (48%), Positives = 211/311 (67%)
Frame = -3
Query: 1169 MGELVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSW 990
M L+ DKH+ Y+ + + + + +HL ++ YW + LL K + + +VS+
Sbjct: 1 MAVLLRDKHISYLHDIGNRTDELDFWLKEHLHVSAIYWSCMSFWLLKKKDQIDKERIVSF 60
Query: 989 LMTCQHESGGFAGNTGHDPHVLYTLSAVQILALFDKLDILDVAKVSSYIAGLQNEDGSFS 810
L++C ESGGFA GHD H+ T+ AVQ+LA+ D L ++D KV+SYI GLQNEDGS
Sbjct: 61 LLSCLTESGGFACYPGHDDHITNTVYAVQVLAMLDSLHVVDKDKVASYIIGLQNEDGSMK 120
Query: 809 GDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQI 630
GD WGE+D RF Y I CL+IL LD +N AVD+++ C N DGGFG PGAESH +
Sbjct: 121 GDRWGEIDARFLYSGINCLAILGKLDYLNKNTAVDWLMKCYNFDGGFGLCPGAESHGAMV 180
Query: 629 FCCVGALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDR 450
F CV AL I L +D++LLGWW+ ERQVK GGLNGRPEKLPD CY WW LS L +I +
Sbjct: 181 FTCVAALKILNKLDLIDEELLGWWISERQVKGGGLNGRPEKLPDSCYGWWDLSPLAIIGK 240
Query: 449 VHWINKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPAYA 270
+ WI++ +L+ F+L QD ++GG +DR +DA D++HT F +AGLSLL++P ++P+DP +
Sbjct: 241 LDWIDRNQLIDFLLGTQDADSGGFADRKEDATDVYHTCFSLAGLSLLQFPNIEPVDPRFC 300
Query: 269 LPVDVINRILL 237
LP++V ++ L
Sbjct: 301 LPLEVTQKMKL 311
>sp|P41992|GGTB2_CAEEL Probable geranylgeranyl transferase type-2 subunit beta
OS=Caenorhabditis elegans GN=ggtb-1 PE=2 SV=2
Length = 335
Score = 311 bits (796), Expect = 7e-084
Identities = 142/299 (47%), Positives = 202/299 (67%)
Frame = -3
Query: 1163 ELVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLM 984
EL+ D H +I EK K S+ ++ +HLR++G YW + +DL +L +S +E+V++++
Sbjct: 23 ELLKDLHANFINQYEKNKNSYHYIMAEHLRVSGIYWCVNAMDLSKQLERMSTEEIVNYVL 82
Query: 983 TCQHESGGFAGNTGHDPHVLYTLSAVQILALFDKLDILDVAKVSSYIAGLQNEDGSFSGD 804
C++ GG+ GHD H+L+TL AVQ L +F+ ++ D +S Y+ GLQ EDGSF GD
Sbjct: 83 GCRNTDGGYGPAPGHDSHLLHTLCAVQTLIIFNSIEKADADTISEYVKGLQQEDGSFCGD 142
Query: 803 MWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFC 624
+ GEVDTRF+ ++ +L L +N++ AV +++ C N DGGFG PG+ESH+GQI+C
Sbjct: 143 LSGEVDTRFTLCSLATCHLLGRLSTLNIDSAVRFLMRCYNTDGGFGTRPGSESHSGQIYC 202
Query: 623 CVGALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVH 444
CVGALAI G L +D+D WL RQ SGGLNGRPEKLPDVCYSWWVL+SL ++ R++
Sbjct: 203 CVGALAIAGRLDEIDRDRTAEWLAFRQCDSGGLNGRPEKLPDVCYSWWVLASLAILGRLN 262
Query: 443 WINKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPAYAL 267
+I+ + KFI CQD E GG +DRP D D FHT FG+A LSL ++ +DP + +
Sbjct: 263 FIDSDAMKKFIYACQDDETGGFADRPGDCADPFHTVFGIAALSLFGDDTLESVDPIFCM 321
>sp|O93830|PGTB2_CANAL Geranylgeranyl transferase type-2 subunit beta OS=Candida
albicans GN=BET2 PE=3 SV=1
Length = 341
Score = 295 bits (754), Expect = 5e-079
Identities = 158/322 (49%), Positives = 210/322 (65%), Gaps = 20/322 (6%)
Frame = -3
Query: 1148 KHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLMTC-QH 972
KHV+YI+ E + SFE + +HLRMNG YWG+T L +++L +++ +V+ ++M C
Sbjct: 17 KHVQYIVEQESHR-SFEYWLSEHLRMNGLYWGVTALITMNELSALAQQDVIDYIMLCWDD 75
Query: 971 ESGGFAGNTGHDPHVLYTLSAVQILALFD-KLDILDVAKVSS----------YIAGLQNE 825
++G F HD H+L TLSA+Q+L ++D +L +L+ SS +I GLQ
Sbjct: 76 KTGAFGSFPKHDGHILSTLSALQVLKIYDQELTVLNDNNESSNGNKRERLIKFITGLQLP 135
Query: 824 DGSFSGDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAES 645
DGSF GD +GEVDTRF Y A+ LS+L L + A +I+ C N DGGFG PG+ES
Sbjct: 136 DGSFQGDKYGEVDTRFVYTAVSSLSLLNALTDSIADTASAFIMQCFNFDGGFGLIPGSES 195
Query: 644 HAGQIFCCVGALAITGSLHHVD----KDLLGWWLCERQV-KSGGLNGRPEKLPDVCYSWW 480
HA Q+F CVGALAI L +D K L WL ERQV SGG NGRPEKLPDVCYSWW
Sbjct: 196 HAAQVFTCVGALAIMNKLDLLDVENKKVKLIDWLTERQVLPSGGFNGRPEKLPDVCYSWW 255
Query: 479 VLSSLIMIDRVHWINKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYP 300
VLSSL ++ R +W++ L FIL CQDLENGG SDRP + D++HT F +AGLSL++Y
Sbjct: 256 VLSSLSILKRKNWVDLKILENFILTCQDLENGGFSDRPGNQTDVYHTCFAIAGLSLIDYK 315
Query: 299 --GVKPIDPAYALPVDVINRIL 240
G K IDP Y +PV+V ++ +
Sbjct: 316 KYGFKEIDPVYCMPVEVTSKFV 337
>sp|O13782|FNTB_SCHPO Protein farnesyltransferase subunit beta
OS=Schizosaccharomyces pombe GN=cpp1 PE=1 SV=1
Length = 382
Score = 134 bits (336), Expect = 2e-030
Identities = 78/237 (32%), Positives = 128/237 (54%), Gaps = 8/237 (3%)
Frame = -3
Query: 1148 KHVRYIL-MAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLPSVSVDEVVSWLMTCQH 972
KH++Y+ M + F V+D R YW L++L +L KL S + +S + +
Sbjct: 33 KHLKYLTKMLDPLPSPF--TVLDASRAWMVYWELSSLAILGKLDSSVCERAISSVRQLKG 90
Query: 971 ESGGFAGNTGHDPHVLYTLSAVQILALFDKLD---ILDVAKVSSYIAGLQNEDGSFSGDM 801
SGGF G G D H+L T +++ + L D D +++ ++ ++ L+N DGSF +
Sbjct: 91 PSGGFCGGNGQDEHLLSTYASILSICLCDSTDAYSLIERDRLYDWLFSLKNPDGSFRVNN 150
Query: 800 WGEVDTRFSYIAICCLSILK-CLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFC 624
GE D R Y A+C S++ +D E + ++ C+ +GG P AE+H G FC
Sbjct: 151 EGESDARSVYAAVCVSSLVGISMDDPLFEGTLQWLCKCQTYEGGLSGVPYAEAHGGYTFC 210
Query: 623 CVGALAITGSLHHVDKDLLGWWLCERQVKS-GGLNGRPEKLPDVCYSWWVLSSLIMI 456
+ A+A+ G L ++++ L WL +RQ + G +GR KL D CYSWWV +S +++
Sbjct: 211 ALAAIALLGGLDNLNEIKLSTWLVQRQDPALYGFSGRSNKLVDGCYSWWVGASHVIV 267
>sp|P49356|FNTB_HUMAN Protein farnesyltransferase subunit beta OS=Homo sapiens
GN=FNTB PE=1 SV=1
Length = 437
Score = 131 bits (328), Expect = 1e-029
Identities = 81/243 (33%), Positives = 123/243 (50%), Gaps = 8/243 (3%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKK-KESFESVVMDHLRMNGAYWGLTTLDLLDK-LPSVSVDEVVSWL 987
L +KH Y+ ++ +++E +D R YW L +L+LLD+ +P + +V +L
Sbjct: 73 LQREKHFHYLKRGLRQLTDAYE--CLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFL 130
Query: 986 MTCQHESGGFAGNTGHDPHVLYTLSAVQILALF---DKLDILDVAKVSSYIAGLQNEDGS 816
CQ GGF G G PH+ T +AV L + + DI++ K+ Y+ L+ DGS
Sbjct: 131 ELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGS 190
Query: 815 FSGDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAG 636
F + GEVD R +Y A S+ + E ++I C+N +GG G PG E+H G
Sbjct: 191 FLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGG 250
Query: 635 QIFCCVGALAITGSLHHVDKDLLGWWLCERQVK-SGGLNGRPEKLPDVCYSWWVLSSLIM 459
FC + AL I ++ L W+ RQ++ GG GR KL D CYS+W L +
Sbjct: 251 YTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPL 310
Query: 458 IDR 450
+ R
Sbjct: 311 LHR 313
>sp|Q8K2I1|FNTB_MOUSE Protein farnesyltransferase subunit beta OS=Mus musculus
GN=Fntb PE=2 SV=1
Length = 437
Score = 129 bits (323), Expect = 5e-029
Identities = 79/243 (32%), Positives = 123/243 (50%), Gaps = 8/243 (3%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKK-KESFESVVMDHLRMNGAYWGLTTLDLLDK-LPSVSVDEVVSWL 987
L +KH Y+ ++ +++E +D R YW L +L+LLD+ +P + +V +L
Sbjct: 73 LQREKHFHYLKRGLRQLTDAYE--CLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFL 130
Query: 986 MTCQHESGGFAGNTGHDPHVLYTLSAVQILALF---DKLDILDVAKVSSYIAGLQNEDGS 816
CQ GGF G G PH+ T +AV L + + ++++ K+ Y+ L+ DGS
Sbjct: 131 ELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGS 190
Query: 815 FSGDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAG 636
F + GEVD R +Y A S+ + E ++I C+N +GG G PG E+H G
Sbjct: 191 FLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGG 250
Query: 635 QIFCCVGALAITGSLHHVDKDLLGWWLCERQVK-SGGLNGRPEKLPDVCYSWWVLSSLIM 459
FC + AL I ++ L W+ RQ++ GG GR KL D CYS+W L +
Sbjct: 251 YTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPL 310
Query: 458 IDR 450
+ R
Sbjct: 311 LHR 313
>sp|Q02293|FNTB_RAT Protein farnesyltransferase subunit beta OS=Rattus
norvegicus GN=Fntb PE=1 SV=1
Length = 437
Score = 129 bits (323), Expect = 5e-029
Identities = 79/243 (32%), Positives = 123/243 (50%), Gaps = 8/243 (3%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKK-KESFESVVMDHLRMNGAYWGLTTLDLLDK-LPSVSVDEVVSWL 987
L +KH Y+ ++ +++E +D R YW L +L+LLD+ +P + +V +L
Sbjct: 73 LQREKHFHYLKRGLRQLTDAYE--CLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFL 130
Query: 986 MTCQHESGGFAGNTGHDPHVLYTLSAVQILALF---DKLDILDVAKVSSYIAGLQNEDGS 816
CQ GGF G G PH+ T +AV L + + ++++ K+ Y+ L+ DGS
Sbjct: 131 ELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGS 190
Query: 815 FSGDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAG 636
F + GEVD R +Y A S+ + E ++I C+N +GG G PG E+H G
Sbjct: 191 FLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGG 250
Query: 635 QIFCCVGALAITGSLHHVDKDLLGWWLCERQVK-SGGLNGRPEKLPDVCYSWWVLSSLIM 459
FC + AL I ++ L W+ RQ++ GG GR KL D CYS+W L +
Sbjct: 251 YTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPL 310
Query: 458 IDR 450
+ R
Sbjct: 311 LHR 313
>sp|P49355|FNTB_BOVIN Protein farnesyltransferase subunit beta OS=Bos taurus
GN=FNTB PE=2 SV=1
Length = 437
Score = 129 bits (322), Expect = 7e-029
Identities = 80/243 (32%), Positives = 122/243 (50%), Gaps = 8/243 (3%)
Frame = -3
Query: 1160 LVADKHVRYILMAEKK-KESFESVVMDHLRMNGAYWGLTTLDLLDK-LPSVSVDEVVSWL 987
L +KH Y+ ++ +++E +D R YW L +L+LLD+ +P + +V +L
Sbjct: 73 LQREKHFHYLKRGLRQLTDAYE--CLDASRPWLCYWILHSLELLDEPIPQMVATDVCQFL 130
Query: 986 MTCQHESGGFAGNTGHDPHVLYTLSAVQILALF---DKLDILDVAKVSSYIAGLQNEDGS 816
CQ GGF G G PH+ T +AV L + + D+++ K+ Y+ L+ DGS
Sbjct: 131 ELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDVINREKLLQYLYSLKQPDGS 190
Query: 815 FSGDMWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAG 636
F GEVD R +Y A S+ + E ++I C+N +GG G PG E+H G
Sbjct: 191 FLMHDGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGG 250
Query: 635 QIFCCVGALAITGSLHHVDKDLLGWWLCERQVK-SGGLNGRPEKLPDVCYSWWVLSSLIM 459
FC + AL I ++ L W+ RQ++ GG GR KL D CYS+W L +
Sbjct: 251 YTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPL 310
Query: 458 IDR 450
+ R
Sbjct: 311 LHR 313
>sp|Q55D51|FNTB_DICDI Protein farnesyltransferase subunit beta OS=Dictyostelium
discoideum GN=fntB PE=3 SV=1
Length = 500
Score = 123 bits (307), Expect = 4e-027
Identities = 63/173 (36%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
Frame = -3
Query: 965 GGFAGNTGHDPHVLYTLSAVQILALF---DKLDILDVAKVSSYIAGLQNEDGSFSGDMWG 795
GGF G H HV+ T +AV L + + +D + ++ ++ ++G+F+ + G
Sbjct: 136 GGFGGGNSHTSHVVSTFAAVSALYVIGTEESYKTIDREAMYKFLMRMKTKEGAFTSEDGG 195
Query: 794 EVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCCVG 615
E D+R +Y AI S+L L VD+++SC+ +GGFG P E+H G FC V
Sbjct: 196 EYDSRTTYCAIAVASMLNILTAELERGVVDFLLSCQTYEGGFGAYPFNEAHGGYTFCSVA 255
Query: 614 ALAITGSLHHVDKDLLGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMI 456
AL+I SLH +D + L W+ RQ GG GR KL D CYS+W + I+I
Sbjct: 256 ALSILNSLHKIDMNSLHRWITYRQSNDGGFEGRTNKLVDTCYSYWQGAVYIII 308
>sp|P53610|PGTB1_RAT Geranylgeranyl transferase type-1 subunit beta OS=Rattus
norvegicus GN=Pggt1b PE=1 SV=1
Length = 377
Score = 122 bits (306), Expect = 5e-027
Identities = 79/225 (35%), Positives = 113/225 (50%), Gaps = 8/225 (3%)
Frame = -3
Query: 932 HVLYTLSAVQ-ILALFDKLDILDVAKVSSYIAGLQNEDGSFSGDMWG-EVDTRFSYIAIC 759
H+ T + + ++ L D L +D + + LQ EDGSF G E D RF Y A C
Sbjct: 121 HIAMTYTGLSCLIILGDDLSRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC 180
Query: 758 CLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCCVGALAITGSLHHV- 582
+L ++++KA+ YI + D G G ESH G FC + +L + G L V
Sbjct: 181 ICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF 240
Query: 581 -DKDL--LGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHWINKAKLVKFI 411
+K+L + W RQ G +GRP K D CYS+WV ++L ++ + N K +I
Sbjct: 241 SEKELNRIKRWCIMRQ--QNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYI 298
Query: 410 LDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPA 276
L QD GG + PD D H YFG+ GLSL+E G+ + PA
Sbjct: 299 LSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPA 343
>sp|P53609|PGTB1_HUMAN Geranylgeranyl transferase type-1 subunit beta OS=Homo
sapiens GN=PGGT1B PE=1 SV=2
Length = 377
Score = 122 bits (305), Expect = 6e-027
Identities = 80/237 (33%), Positives = 116/237 (48%), Gaps = 8/237 (3%)
Frame = -3
Query: 932 HVLYTLSAVQILALF-DKLDILDVAKVSSYIAGLQNEDGSFSGDMWG-EVDTRFSYIAIC 759
H+ T + + L + D L ++ + + LQ EDGSF G E D RF Y A C
Sbjct: 121 HIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC 180
Query: 758 CLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCCVGALAITGSLHHV- 582
+L ++++KA+ YI + D G G ESH G FC + +L + G L V
Sbjct: 181 ICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF 240
Query: 581 -DKDL--LGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHWINKAKLVKFI 411
+K+L + W RQ G +GRP K D CYS+WV ++L ++ + N K +I
Sbjct: 241 SEKELNRIKRWCIMRQ--QNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYI 298
Query: 410 LDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPAYALPVDVINRIL 240
L QD GG + PD D H YFG+ GLSL+E G+ + PA + R+L
Sbjct: 299 LSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLL 355
>sp|Q8BUY9|PGTB1_MOUSE Geranylgeranyl transferase type-1 subunit beta OS=Mus
musculus GN=Pggt1b PE=2 SV=1
Length = 377
Score = 122 bits (305), Expect = 6e-027
Identities = 79/225 (35%), Positives = 113/225 (50%), Gaps = 8/225 (3%)
Frame = -3
Query: 932 HVLYTLSAVQ-ILALFDKLDILDVAKVSSYIAGLQNEDGSFSGDMWG-EVDTRFSYIAIC 759
H+ T + + ++ L D L +D + + LQ EDGSF G E D RF Y A C
Sbjct: 121 HIAMTYTGLSCLIILGDDLGRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC 180
Query: 758 CLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCCVGALAITGSLHHV- 582
+L ++++KA+ YI + D G G ESH G FC + +L + G L V
Sbjct: 181 ICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF 240
Query: 581 -DKDL--LGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHWINKAKLVKFI 411
+K+L + W RQ G +GRP K D CYS+WV ++L ++ + N K +I
Sbjct: 241 SEKELNRIKRWCIMRQ--QNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYI 298
Query: 410 LDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPA 276
L QD GG + PD D H YFG+ GLSL+E G+ + PA
Sbjct: 299 LSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPA 343
>sp|Q5EAD5|PGTB1_BOVIN Geranylgeranyl transferase type-1 subunit beta OS=Bos
taurus GN=PGGT1B PE=2 SV=1
Length = 377
Score = 121 bits (303), Expect = 1e-026
Identities = 78/225 (34%), Positives = 113/225 (50%), Gaps = 8/225 (3%)
Frame = -3
Query: 932 HVLYTLSAVQILALF-DKLDILDVAKVSSYIAGLQNEDGSFSGDMWG-EVDTRFSYIAIC 759
H+ T + + L + D L ++ + + LQ EDGSF G E D RF Y A C
Sbjct: 121 HIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC 180
Query: 758 CLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTPGAESHAGQIFCCVGALAITGSLHHV- 582
+L ++++KA++YI + D G G ESH G FC + +L + G L V
Sbjct: 181 ICYMLNNWSGMDMKKAINYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF 240
Query: 581 -DKDL--LGWWLCERQVKSGGLNGRPEKLPDVCYSWWVLSSLIMIDRVHWINKAKLVKFI 411
+K+L + W RQ G +GRP K D CYS+WV ++L ++ + N K +I
Sbjct: 241 SEKELNRIKRWCIMRQ--QNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYI 298
Query: 410 LDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEYPGVKPIDPA 276
L QD GG + PD D H YFG+ GLSL+E G+ + PA
Sbjct: 299 LSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPA 343
>sp|Q55DA3|PGTB1_DICDI Geranylgeranyl transferase type-1 subunit beta
OS=Dictyostelium discoideum GN=pggt1b PE=2 SV=1
Length = 352
Score = 119 bits (297), Expect = 5e-026
Identities = 67/192 (34%), Positives = 102/192 (53%), Gaps = 5/192 (2%)
Frame = -3
Query: 833 QNEDGSFSGD-MWGEVDTRFSYIAICCLSILKCLDKINVEKAVDYIVSCKNLDGGFGCTP 657
+ DG+ SG G+ D R + A IL IN E A+DYI SC + + FG TP
Sbjct: 149 RESDGAISGSPNVGDYDLRHLFSACAISFILDDWSAINKESAIDYIKSCLSYEFAFGQTP 208
Query: 656 GAESHAGQIFCCVGALAITGSLHHVD--KDLLGWWLCERQVKSGGLNGRPEKLPDVCYSW 483
E+H G +C + +L++ G L ++ K+ L +WL ++Q+ G GR K PD CY++
Sbjct: 209 QQEAHGGPTYCAIASLSLLGRLDVLEPFKEQLTFWLVKKQIT--GFCGRTNKDPDTCYAF 266
Query: 482 WVLSSLIMIDRVHWINKAKLVKFILDCQDLENGGISDRPDDAVDIFHTYFGVAGLSLLEY 303
W+ +SL+MIDR I+ A + FI Q GG++ P D+ H+Y + GLS
Sbjct: 267 WIGASLMMIDRYDLIDFASINAFIGSAQHEAIGGVAKEPGQLPDVMHSYLSLVGLSFGNI 326
Query: 302 PGVKPIDPAYAL 267
P ++ + P L
Sbjct: 327 PSIQQVIPCLNL 338
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,471,325,924
Number of Sequences: 518415
Number of Extensions: 72471325924
Number of Successful Extensions: 505334272
Number of sequences better than 0.0: 0
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