BLASTX 7.6.2
Query= UN17390 /QuerySize=1472
(1471 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P50053|KHK_HUMAN Ketohexokinase OS=Homo sapiens GN=KHK PE=1 SV=1 66 5e-010
sp|P32143|YIHV_ECOLI Uncharacterized sugar kinase yihV OS=Escher... 64 2e-009
sp|O27587|Y1544_METTH Uncharacterized sugar kinase MTH_1544 OS=M... 63 4e-009
sp|Q9H477|RBSK_HUMAN Ribokinase OS=Homo sapiens GN=RBKS PE=1 SV=1 62 1e-008
sp|Q02974|KHK_RAT Ketohexokinase OS=Rattus norvegicus GN=Khk PE=... 59 8e-008
sp|Q5RD71|KHK_PONAB Ketohexokinase OS=Pongo abelii GN=KHK PE=3 SV=1 58 1e-007
sp|Q8R1Q9|RBSK_MOUSE Ribokinase OS=Mus musculus GN=Rbks PE=1 SV=1 58 1e-007
sp|P97328|KHK_MOUSE Ketohexokinase OS=Mus musculus GN=Khk PE=1 SV=1 57 3e-007
sp|P36945|RBSK_BACSU Ribokinase OS=Bacillus subtilis GN=rbsK PE=... 54 3e-006
sp|P44331|RBSK_HAEIN Ribokinase OS=Haemophilus influenzae GN=rbs... 53 4e-006
>sp|P50053|KHK_HUMAN Ketohexokinase OS=Homo sapiens GN=KHK PE=1 SV=1
Length = 298
Score = 66 bits (160), Expect = 5e-010
Identities = 57/230 (24%), Positives = 96/230 (41%), Gaps = 16/230 (6%)
Frame = -1
Query: 1270 VLGCGGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVAN 1091
+L G +D ++ VD YPK D +IR S + Q GGNA N+ T + LG + +A
Sbjct: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65
Query: 1090 DSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCIHTPGYPPMVPTDLP 911
+L++L VD + V G+ P VI+++ + +RT ++ P V
Sbjct: 66 GHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDV----- 120
Query: 910 HSTMLSALDRASIAYFDVRLHETALVI----------AKEASRKKIPILVDAEKKRDGLD 761
+T +D + + + + ++ +KI + V+ EK R+ L
Sbjct: 121 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180
Query: 760 DLLQLADYVVCTAKFPQAWTEASSIPCALVSMMLRLPKLKFVIVTLGEEG 611
L D VV +K S AL + R+ K ++ EEG
Sbjct: 181 QLFGYGD-VVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEG 229
>sp|P32143|YIHV_ECOLI Uncharacterized sugar kinase yihV OS=Escherichia coli
(strain K12) GN=yihV PE=3 SV=2
Length = 298
Score = 64 bits (155), Expect = 2e-009
Identities = 61/243 (25%), Positives = 103/243 (42%), Gaps = 11/243 (4%)
Frame = -1
Query: 1273 IVLGCGGTTV-DFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKV 1097
I + C G TV D + V+ P K + + GGG A A AARLG I +V
Sbjct: 2 IRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGRV 61
Query: 1096 ANDSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCIHTPGYPPMVPTD 917
+D G +L ELES GV+T + + + + ++VD + + R I+ P P
Sbjct: 62 GDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDTKGE-RIIINYPS-----PDL 115
Query: 916 LPHSTMLSALD--RASIAYFDVRLHETALVIAKEASRKKIPILVDAEKKRDGLDDLLQLA 743
LP + L +D + + DVR H+ A A + + ++D + + +L+ L+
Sbjct: 116 LPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLDGDITPQDISELVALS 175
Query: 742 DYVVCTAKFPQAWTEASSIPCALVSMMLRLPKLKFVIVTLGEEGCLMIQRDSTETSESKE 563
D+ + T + AL + V VT G GC ++ + + +
Sbjct: 176 DHAAFSEPGLARLTGVKEMASAL--KQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFK 233
Query: 562 TDI 554
D+
Sbjct: 234 VDV 236
>sp|O27587|Y1544_METTH Uncharacterized sugar kinase MTH_1544 OS=Methanobacterium
thermoautotrophicum GN=MTH_1544 PE=3 SV=1
Length = 309
Score = 63 bits (152), Expect = 4e-009
Identities = 31/102 (30%), Positives = 54/102 (52%)
Frame = -1
Query: 1285 TDDGIVLGCGGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLI 1106
++D +L G T D++ +D +P+P+ ++ GG A N +RLGL + L+
Sbjct: 2 SEDRDLLAVGHTAFDYIIHLDEFPEPNTSTAIKRMRNLHGGAAANVALVGSRLGLRTSLV 61
Query: 1105 SKVANDSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVD 980
S V D +G E LES G+D +++ + +TP +V+ D
Sbjct: 62 SAVGGDFEGSEYRELLESSGIDIESMILVADESTPTAFVMTD 103
>sp|Q9H477|RBSK_HUMAN Ribokinase OS=Homo sapiens GN=RBKS PE=1 SV=1
Length = 322
Score = 62 bits (149), Expect = 1e-008
Identities = 53/234 (22%), Positives = 94/234 (40%), Gaps = 5/234 (2%)
Frame = -1
Query: 1270 VLGCGGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVAN 1091
V+ G D ++ PK + I + GG N AARLG + ++ KV
Sbjct: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
Query: 1090 DSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCIHTPGYPPMVPTDLP 911
DS G +E L+ + + T F +K+ T +IV+ + + I + DL
Sbjct: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
Query: 910 HSTMLSALDRASIAYFDVRLHETALVIAKEASRKKIPILVDAEKKRDGLD-DLLQLADYV 734
+ + + + + ++ T+L A R + L + LD L+D
Sbjct: 138 AAANVISRAKVMVCQLEI-TPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
Query: 733 VCT---AKFPQAWTEASSIPCALVSMMLRLPKLKFVIVTLGEEGCLMIQRDSTE 581
C A+ T S+ +++L + VI+TLG EGC+++ + E
Sbjct: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
>sp|Q02974|KHK_RAT Ketohexokinase OS=Rattus norvegicus GN=Khk PE=1 SV=1
Length = 298
Score = 59 bits (141), Expect = 8e-008
Identities = 59/234 (25%), Positives = 96/234 (41%), Gaps = 24/234 (10%)
Frame = -1
Query: 1270 VLGCGGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVAN 1091
+L G +D + VD YP+ D R S + Q GGNA N+ T + LG + +A+
Sbjct: 6 ILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAH 65
Query: 1090 DSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCIHTPGYPPMVPTDLP 911
++ + GVD S + +G+TP + IV+ +RT I + T+LP
Sbjct: 66 GHVADFLVADFRRRGVDVSQVAWQSQGDTPCSCCIVNNSNGSRTII-------LYDTNLP 118
Query: 910 HSTM--LSALDRASIAYFDVR----------LHETALVIAKEASRKKIPILVDAEKKRDG 767
+ +D + + L A + ++K+ + V+ EK R
Sbjct: 119 DVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEQYNATQPLQQKVRVSVEIEKPR-- 176
Query: 766 LDDLLQLADY--VVCTAKFPQAWTEASSIPCALVSMMLRLPKLKFVIVTLGEEG 611
++L QL Y VV +K S AL + R+ K +I EEG
Sbjct: 177 -EELFQLFGYGEVVFVSKDVAKHLGFRSAGEALKGLYSRVKKGATLICAWAEEG 229
>sp|Q5RD71|KHK_PONAB Ketohexokinase OS=Pongo abelii GN=KHK PE=3 SV=1
Length = 297
Score = 58 bits (139), Expect = 1e-007
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Frame = -1
Query: 1270 VLGCGGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVAN 1091
+L G +D ++ VD YPK D +IR S + Q GGNA N+ T + LG + +A
Sbjct: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA- 64
Query: 1090 DSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCI-HTPGYPPMVPTD 917
++ + GVD S + +G+TP + I++ RT + H P + TD
Sbjct: 65 PGHVAFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD 123
>sp|Q8R1Q9|RBSK_MOUSE Ribokinase OS=Mus musculus GN=Rbks PE=1 SV=1
Length = 323
Score = 58 bits (139), Expect = 1e-007
Identities = 49/231 (21%), Positives = 91/231 (39%), Gaps = 7/231 (3%)
Frame = -1
Query: 1270 VLGCGGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVAN 1091
V+ G D ++ PK + I + GG N AARLG + ++ KV N
Sbjct: 19 VVVVGSCMTDLVSLTSRLPKTGETIHGHEFFIGFGGKGANQCVQAARLGAKAAIVCKVGN 78
Query: 1090 DSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCIHTPGYPPMVPTDLP 911
DS G +E L+ + + T F +++ T +IV+ + + I + DL
Sbjct: 79 DSFGNDYIENLKQNHISTEFTYQTRDAATGTASIIVNNEGQNIIVIVAGANLFLNSEDLK 138
Query: 910 HSTMLSALDRASIAYFDVRLHETALVIAKEASRKK-IPILVDAEKKRDGLDDLLQLADYV 734
+ S + RA + + + A + A +R+ + L + LD +
Sbjct: 139 KAA--SVISRAKVMICQLEISPAASLEALTMARRSGVKTLFNPAPAMADLDPQFYTLSSI 196
Query: 733 VC----TAKFPQAWTEASSIPCALVSMMLRLPKLKFVIVTLGEEGCLMIQR 593
C A+ + +M+L + V++TLG GC+++ +
Sbjct: 197 FCCNESEAEILTGHAVSDPTTAGKAAMILLERGCQVVVITLGASGCVILSQ 247
>sp|P97328|KHK_MOUSE Ketohexokinase OS=Mus musculus GN=Khk PE=1 SV=1
Length = 298
Score = 57 bits (136), Expect = 3e-007
Identities = 46/191 (24%), Positives = 79/191 (41%), Gaps = 19/191 (9%)
Frame = -1
Query: 1270 VLGCGGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVAN 1091
+L G +D + VD YP+ D R S + Q GGNA N+ T + LG + +A
Sbjct: 6 ILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAP 65
Query: 1090 DSQGKGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCIHTPGYPPMVPTDLP 911
++ + GVD S + +G+TP + IV+ +RT I + T+LP
Sbjct: 66 GHVADFLVADFRQRGVDVSQVTWQSQGDTPCSCCIVNNSNGSRTII-------LYDTNLP 118
Query: 910 HSTM--LSALDRASIAYFDVRLHETALVI----------AKEASRKKIPILVDAEKKRDG 767
+ +D + + + + AK+ +K+ + V+ EK R+
Sbjct: 119 DVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEEHNAKQPLPQKVRVSVEIEKPREE 178
Query: 766 LDDLLQLADYV 734
L L + V
Sbjct: 179 LFQLFSYGEVV 189
>sp|P36945|RBSK_BACSU Ribokinase OS=Bacillus subtilis GN=rbsK PE=3 SV=2
Length = 293
Score = 54 bits (128), Expect = 3e-006
Identities = 26/77 (33%), Positives = 40/77 (51%)
Frame = -1
Query: 1258 GGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVANDSQG 1079
G ++D + T D PK + + TS + GG N AARLG ++ KV +D G
Sbjct: 8 GSCSMDLVVTSDKRPKAGETVLGTSFQTVPGGKGANQAVAAARLGAQVFMVGKVGDDHYG 67
Query: 1078 KGILEELESDGVDTSFL 1028
IL L+++GV T ++
Sbjct: 68 TAILNNLKANGVRTDYM 84
>sp|P44331|RBSK_HAEIN Ribokinase OS=Haemophilus influenzae GN=rbsK PE=3 SV=1
Length = 306
Score = 53 bits (126), Expect = 4e-006
Identities = 52/234 (22%), Positives = 98/234 (41%), Gaps = 22/234 (9%)
Frame = -1
Query: 1258 GGTTVDFLATVDSYPKPDDKIRSTSLKVQGGGNAGNALTCAARLGLTSRLISKVANDSQG 1079
G D + +V + KP + + + ++ GG N AARLG IS + +DS G
Sbjct: 9 GSINADHVISVPYFTKPGETLTGQNYQIAYGGKGANQAVAAARLGAKVAFISCIGSDSIG 68
Query: 1078 KGILEELESDGVDTSFLVVSKEGNTPFTYVIVDKQTKTRTCIHTPGYPPMVPTDLPHSTM 899
K + +G+DT+ + + T ++ V K ++ + + + S M
Sbjct: 69 KTMKNAFAQEGIDTTHINTVSQEMTGMAFIQVAKSSENSIVLASGANSHL-------SEM 121
Query: 898 LSALDRASIAYFDVRLH--ETAL----VIAKEASRKKIPILVDAEKKRDGLDDLLQLADY 737
+ A IA D L ET L + A+ A + + ++++ + D+LL L D
Sbjct: 122 VVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVKVVLNPAPAQILSDELLSLIDI 181
Query: 736 VVCTAKFPQAWT------EASSIPCALVSMMLRLPKLKFVIVTLGEEGCLMIQR 593
+ + T E S++ A V ++ V++TLG +G + ++
Sbjct: 182 ITPNETEAEILTGVEVADEQSAVKAASV---FHDKGIETVMITLGAKGVFVSRK 232
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,471,325,924
Number of Sequences: 518415
Number of Extensions: 72471325924
Number of Successful Extensions: 505334272
Number of sequences better than 0.0: 0
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