BLASTX 7.6.2
Query= UN17434 /QuerySize=1167
(1166 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 ... 422 4e-117
sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 ... 388 6e-107
sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 ... 369 2e-101
sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 ... 241 1e-062
sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 ... 241 1e-062
sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 ... 240 1e-062
sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 ... 239 3e-062
sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 ... 237 2e-061
sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2... 233 2e-060
sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 ... 233 3e-060
sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation ... 231 1e-059
sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 ... 216 3e-055
sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 ... 192 6e-048
sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 ... 178 9e-044
sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit bet... 102 8e-021
sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit bet... 100 2e-020
sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit bet... 99 4e-020
sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit bet... 99 7e-020
sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit bet... 98 1e-019
sp|Q5V323|IF2B_HALMA Translation initiation factor 2 subunit bet... 92 8e-018
>sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 subunit beta
OS=Arabidopsis thaliana GN=EMB1401 PE=2 SV=3
Length = 268
Score = 422 bits (1083), Expect = 4e-117
Identities = 219/271 (80%), Positives = 239/271 (88%), Gaps = 8/271 (2%)
Frame = +2
Query: 104 NELKEVKDEQE-LAPFDPTKKKKKKKVVLQDPIEEPTE-SPAEPSDSLPANDGGLDGPSF 277
+E+ E+++EQE LAPFDP+KKKKKKKVV+Q+P+E+ E S E SDSLP ND GL+ SF
Sbjct: 3 DEINEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVND-GLES-SF 60
Query: 278 GTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEA-EGIDLQQQQQRYPWEGSDRDYI 454
KKKKKKP ESS L++ESVDA EDL+E N+E+E EGI L QQRYPWEGS+RDYI
Sbjct: 61 TGMKKKKKKPTESSLLNNESVDAGEDLDEIANDEQEGEEGIVL---QQRYPWEGSERDYI 117
Query: 455 YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 634
YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV
Sbjct: 118 YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 177
Query: 635 MNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENR 814
M +LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY+T+YVICLGCKSPDTILSKENR
Sbjct: 178 MQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENR 237
Query: 815 LFFFRCEKCGSGRSVAQIKAGFVARVGRRKT 907
LFF RCEKCGS RSVA IK GFVARV RRKT
Sbjct: 238 LFFLRCEKCGSQRSVAPIKTGFVARVSRRKT 268
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 subunit beta
OS=Malus domestica PE=2 SV=2
Length = 271
Score = 388 bits (995), Expect = 6e-107
Identities = 198/264 (75%), Positives = 220/264 (83%), Gaps = 6/264 (2%)
Frame = +2
Query: 116 EVKDE--QELAPFDPTKKKKKKKVVLQDPIEEPTESPAEPSDSLPANDGGLDGPSFGTKK 289
EVKDE ++APFDPTKKKKKK+VV+QD ++ AE +++ A++G +F K
Sbjct: 8 EVKDEVVADIAPFDPTKKKKKKEVVIQDTTDDSVGKLAEKAEACTASEG--QESTFAGLK 65
Query: 290 KKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAEGIDLQQQQQRYPWEGSDRDYIYDELL 469
KKKKKP+E+S L++ES DA EDL E E+EE EGI L+ YPWEGSDRDY Y+ELL
Sbjct: 66 KKKKKPIETSILNEESGDAVEDLNERTGEDEEGEGIVLETPS--YPWEGSDRDYTYEELL 123
Query: 470 GRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLL 649
RVF ILRENNP+LAGDRRRTVMRPPQVLREGTKK VFVNFMDLCKTMHRQPDHVM FLL
Sbjct: 124 DRVFTILRENNPDLAGDRRRTVMRPPQVLREGTKKAVFVNFMDLCKTMHRQPDHVMAFLL 183
Query: 650 AELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFFR 829
AELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYV EYVICLGC+SPDTILSKENRLFF R
Sbjct: 184 AELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVNEYVICLGCQSPDTILSKENRLFFLR 243
Query: 830 CEKCGSGRSVAQIKAGFVARVGRR 901
CEKCGSGRSVA KAGF+ARVGRR
Sbjct: 244 CEKCGSGRSVAPNKAGFMARVGRR 267
>sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 subunit beta
OS=Triticum aestivum PE=1 SV=1
Length = 270
Score = 369 bits (947), Expect = 2e-101
Identities = 189/266 (71%), Positives = 215/266 (80%), Gaps = 4/266 (1%)
Frame = +2
Query: 107 ELKEVKDEQELAPFDPTKKKKKKKVVLQDPIEEPTESPAEPSDSLPANDGGLDGPSFGTK 286
+++ ++ E+APFDPTKKKKKKKVV+QDP +E + AE ++ L + G SF
Sbjct: 6 QMERKEEATEIAPFDPTKKKKKKKVVIQDPADE-VDKLAEKTEGLSVTESG--EASFVGL 62
Query: 287 KKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAEGIDLQQQQQRYPWEGSDRDYIYDEL 466
KKKKKK VE E+ D + L++ E+E+ EGI L Q YPWEG+DRDY YDEL
Sbjct: 63 KKKKKKLVELDPSLVEAGDGEDTLDDQVGEDEQGEGIVLGGATQ-YPWEGTDRDYKYDEL 121
Query: 467 LGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFL 646
LGRVFNILRENNP+LAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP+HVM FL
Sbjct: 122 LGRVFNILRENNPDLAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPEHVMMFL 181
Query: 647 LAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFF 826
LAE+GTSGSLDGQQRLV+KGRFAPKNFE ILRRY+ EYVIC GCKSPDTILSKENRLFF
Sbjct: 182 LAEMGTSGSLDGQQRLVIKGRFAPKNFEAILRRYINEYVICHGCKSPDTILSKENRLFFL 241
Query: 827 RCEKCGSGRSVAQIKAGFVARVGRRK 904
RCE+CGS RSVA IKAGFVA+VGRRK
Sbjct: 242 RCEQCGSSRSVAPIKAGFVAQVGRRK 267
>sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2
OS=Homo sapiens GN=EIF2S2 PE=1 SV=2
Length = 333
Score = 241 bits (613), Expect = 1e-062
Identities = 138/291 (47%), Positives = 182/291 (62%), Gaps = 8/291 (2%)
Frame = +2
Query: 41 SQNQPFSPKVNFSVAIMADENNELKE--VKDEQELAPFDPTKKKKK-KKVVLQDPIEEPT 211
S+ + P+ + ADE + K+ D +L F+ KKKKK KK+ D EE
Sbjct: 39 SETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGV 98
Query: 212 ESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAE 391
+ SD + D KKKKKK V+ +DE ++ E LE+ N+++ +
Sbjct: 99 KDLKIESDVQEPTEPEDDLDIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDNKKD--D 155
Query: 392 GIDLQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGT 568
GI Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GT
Sbjct: 156 GISFSNQTGP-AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGT 214
Query: 569 KKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY 748
KKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY
Sbjct: 215 KKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRY 274
Query: 749 VTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
+ EYV C C+SPDTIL K+ RL+F +CE C S SVA IK GF A G+R
Sbjct: 275 IKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2
OS=Mus musculus GN=Eif2s2 PE=1 SV=1
Length = 331
Score = 241 bits (613), Expect = 1e-062
Identities = 137/291 (47%), Positives = 183/291 (62%), Gaps = 10/291 (3%)
Frame = +2
Query: 41 SQNQPFSPKVNFSVAIMADENNELKE--VKDEQELAPFDPTKKKKK-KKVVLQDPIEEPT 211
S+ + P+ + ADE + K+ D +L F+ KKKKK KK+ D EE
Sbjct: 39 SETKEVEPEPTEEKDVDADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAI 98
Query: 212 ESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAE 391
+ SD+ + D KKKKKK V+ +DE ++ E LE+ ++++ +
Sbjct: 99 KDVKIESDAQEPAEPEDDLDIMLGNKKKKKKNVKFPE-EDEILEKDEALEDEDSKKD--D 155
Query: 392 GIDLQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGT 568
GI Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GT
Sbjct: 156 GISFSSQT---AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGT 212
Query: 569 KKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY 748
KKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY
Sbjct: 213 KKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRY 272
Query: 749 VTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
+ EYV C C+SPDTIL K+ RL+F +CE C S SVA IK GF A G+R
Sbjct: 273 IKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 323
>sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 subunit 2
OS=Bos taurus GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 240 bits (612), Expect = 1e-062
Identities = 137/291 (47%), Positives = 181/291 (62%), Gaps = 8/291 (2%)
Frame = +2
Query: 41 SQNQPFSPKVNFSVAIMADENNELKE--VKDEQELAPFDPTKKKKKKKVVLQ-DPIEEPT 211
S+ + P+ + ADE + K+ D +L F+ KKKKK K + D EE
Sbjct: 39 SETKEVEPEPTEDKDVEADEEDSRKKDASDDLDDLNFFNQKKKKKKSKKIFDIDEAEEGI 98
Query: 212 ESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAE 391
+ SD + D KKKKKK V+ +DE ++ E LE+ ++++ +
Sbjct: 99 KDLKIESDVQEPAEPEEDLDIMLGNKKKKKKVVKFPD-EDEVLEKDEALEDEDSKKD--D 155
Query: 392 GIDLQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGT 568
GI Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GT
Sbjct: 156 GISFSNQTGP-AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGT 214
Query: 569 KKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY 748
KKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY
Sbjct: 215 KKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRY 274
Query: 749 VTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
+ EYV C C+SPDTIL K+ RL+F +CE C S SVA IK GF A GRR
Sbjct: 275 IKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGRR 325
>sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 subunit 2
OS=Pongo abelii GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 239 bits (609), Expect = 3e-062
Identities = 137/291 (47%), Positives = 181/291 (62%), Gaps = 8/291 (2%)
Frame = +2
Query: 41 SQNQPFSPKVNFSVAIMADENNELKE--VKDEQELAPFDPTKKKKK-KKVVLQDPIEEPT 211
S+ + P+ + ADE + K+ D +L F+ KKKKK KK+ D EE
Sbjct: 39 SETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGV 98
Query: 212 ESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAE 391
+ SD + D KKKKKK V+ +DE ++ E LE+ N+++ +
Sbjct: 99 KDLKIESDVQEPTEPEDDLDIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDNKKD--D 155
Query: 392 GIDLQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGT 568
GI Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GT
Sbjct: 156 GISFSNQTGP-AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGT 214
Query: 569 KKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY 748
KKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY
Sbjct: 215 KKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRY 274
Query: 749 VTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
+ EYV C C+SPDTIL K+ RL+F +CE C S S A IK GF A G+R
Sbjct: 275 IKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSAASIKTGFQAVTGKR 325
>sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 subunit 2
OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
Length = 333
Score = 237 bits (603), Expect = 2e-061
Identities = 132/272 (48%), Positives = 177/272 (65%), Gaps = 7/272 (2%)
Frame = +2
Query: 95 DENNELKEVKDE-QELAPFDPTKKKKK-KKVVLQDPIEEPTESPAEPSDSLPANDGGLDG 268
+E++ K+ D+ +L F+ KKKKK KK+ D EE + +D + D
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIENDVQEPAEPEDDL 117
Query: 269 PSFGTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAEGIDLQQQQQRYPWEGSDRD 448
KKKKKK V+ +DE ++ E LE+ ++++ +GI Q W GS+RD
Sbjct: 118 DIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDSKKD--DGISFSNQTGP-AWAGSERD 173
Query: 449 YIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP 625
Y Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HRQP
Sbjct: 174 YTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQP 233
Query: 626 DHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSK 805
H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL K
Sbjct: 234 KHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQK 293
Query: 806 ENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
+ RL+F +CE C S SVA IK GF A G+R
Sbjct: 294 DTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2 subunit 2-like
protein OS=Homo sapiens PE=1 SV=1
Length = 327
Score = 233 bits (594), Expect = 2e-060
Identities = 137/291 (47%), Positives = 179/291 (61%), Gaps = 14/291 (4%)
Frame = +2
Query: 41 SQNQPFSPKVNFSVAIMADENNELKE--VKDEQELAPFDPTKKKKK-KKVVLQDPIEEPT 211
S+ + P+ + ADE + K+ D +L F+ KKKKK KK+ D EE
Sbjct: 39 SETKEVEPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGV 98
Query: 212 ESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAE 391
+ SD + D KKKKKK V+ D E LE+ N+++ +
Sbjct: 99 KDLKIESDVQEPTEPEDDLDIMLGNKKKKKKNVKFP-------DEDEALEDEDNKKD--D 149
Query: 392 GIDLQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGT 568
GI Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GT
Sbjct: 150 GISFSNQTGP-AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGT 208
Query: 569 KKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY 748
KKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY
Sbjct: 209 KKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRY 268
Query: 749 VTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
+ EYV C C+SPDTIL K+ RL+F +CE C S SVA IK GF A +G+R
Sbjct: 269 IKEYVTCHTCRSPDTILQKDMRLYFLQCETCHSRCSVAIIKIGFQAVMGKR 319
>sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 subunit 2
OS=Drosophila melanogaster GN=eIF-2beta PE=1 SV=1
Length = 312
Score = 233 bits (592), Expect = 3e-060
Identities = 131/269 (48%), Positives = 166/269 (61%), Gaps = 26/269 (9%)
Frame = +2
Query: 122 KDEQELAPFDPTKKKKKKKVVLQDPIEEPTESPAEPSDSLPANDG--------GLDGPSF 277
+D +L F KKKKKKK D IE P+ D + A++ +D
Sbjct: 53 EDNLDLESFG-KKKKKKKKPFNMDEIE--AAIPSFGGDDVAASEEPEEEEINLDMDFSMA 109
Query: 278 GTKKKKKKKPVESSSLDDESVDAPEDLEEHPNEEEEAEGIDLQQQQQRYPWEGSDRDYIY 457
KKK KKK ++ D D ED E N+E+ + W GSDRDY Y
Sbjct: 110 KKKKKSKKKELDELFADQADDDKSEDKE---NDEDNSS-----------TWFGSDRDYTY 155
Query: 458 DELLGRVFNILRENNPELAGDRR-RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 634
DELL RVF I+ + NP++A R+ + VMRPPQVLR GTKKT F NFMD+ KT+HR P H+
Sbjct: 156 DELLKRVFEIILDKNPDMAAGRKPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHL 215
Query: 635 MNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENR 814
++FLLAELGTSGS+DG Q+L++KGRF PK E +LRRY+ EYV C C+SP+TIL K+ R
Sbjct: 216 LDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDTR 275
Query: 815 LFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
LFF +CE CGS SVA IK+GF A G+R
Sbjct: 276 LFFLQCESCGSRCSVASIKSGFQAVTGKR 304
>sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation factor 2
subunit beta OS=Schizosaccharomyces pombe GN=tif212 PE=1 SV=2
Length = 321
Score = 231 bits (587), Expect = 1e-059
Identities = 133/303 (43%), Positives = 170/303 (56%), Gaps = 38/303 (12%)
Frame = +2
Query: 20 SLSQIDSSQNQPFSPKVNFSVAIMADENNELKEVKDEQELAPFDPTKKKKKKKVVLQDPI 199
S D ++ S + + + E +ELK++ F KKKKK K
Sbjct: 46 SAGATDEDDSERKSSAKDLTTPVTEGEVDELKDM--------FSSMKKKKKSK------- 90
Query: 200 EEPTESPAEPSDSLPANDGGLDGPSFGTKKKKKK--------KPVESSSLDDESVDAPED 355
+ + S E ++ + G LD S KKKKKK K +E+SS D + D +
Sbjct: 91 -KSSASAEEQTEDITTESGELDFSSMKKKKKKKKSADLSAFEKELEASSTGDATSDLSKQ 149
Query: 356 LEEHPNEEEEAEGIDLQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTV 535
+ N E A W SDRDY Y ELL R F +LR NNPELAG++R+
Sbjct: 150 TFDSENMGEHA-------------WLKSDRDYYYPELLNRFFTLLRTNNPELAGEKRKYT 196
Query: 536 MRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFA 715
+ PP V REG KKT+F N D+ K MHR DHV+ FL AELGTSGS+DG RL++KGRF
Sbjct: 197 IVPPSVHREG-KKTIFANISDISKRMHRSLDHVIQFLFAELGTSGSVDGSSRLIIKGRFQ 255
Query: 716 PKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVG 895
K E +LRRY+ EYV C CKSPDTIL+KENR+FF CE CGS RSV IK G+ A++G
Sbjct: 256 QKQIENVLRRYIVEYVTCKTCKSPDTILTKENRIFFMTCEACGSVRSVQAIKTGYQAQIG 315
Query: 896 RRK 904
+RK
Sbjct: 316 KRK 318
>sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 subunit 2
OS=Dictyostelium discoideum GN=eif2s2 PE=3 SV=1
Length = 317
Score = 216 bits (549), Expect = 3e-055
Identities = 113/291 (38%), Positives = 171/291 (58%), Gaps = 15/291 (5%)
Frame = +2
Query: 26 SQIDSSQNQPFSPKVNFSVAIMADENNELKEVKDEQELAPFDPTKKKKKKKVVLQDPIEE 205
S+ ++Q + K+ M + + +E +DE++ +K+KKKK L E
Sbjct: 22 SKDSAAQTEEEKKKLKSKTLAMMSQQEDEQEQEDEKK-------EKRKKKKAALLASTEG 74
Query: 206 PTESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVES-SSLDDESVDAPEDLEEHPNEEE 382
E ++ A+D ++ G KKKKKK S ++ + E E P E+
Sbjct: 75 ENSEAIEKLENEGAHDEDIEAEFMGEKKKKKKSSKSSTTTTTSTTTTTTEPTETEPTEDG 134
Query: 383 EAEGIDLQQQ------QQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRP 544
E++ + Q PW G+DRDY Y EL R++++L+ NNP+L D++RT M+P
Sbjct: 135 ESKEKTITTSDGDTFVQGTIPWAGTDRDYKYSELTYRIYHLLQANNPDLISDQKRT-MKP 193
Query: 545 PQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKN 724
PQV+REGTKKT++ NF ++C T++R+ +HV N++ AELGT+GS+DG QRLV++GRF
Sbjct: 194 PQVMREGTKKTIWANFAEICGTLNRKVEHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQ 253
Query: 725 FEGILRRYVTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKAG 877
E ++R Y++EYV C CKSP+T+L + NRL+F C C S RSVA IK G
Sbjct: 254 IEIVIRHYISEYVACRNCKSPNTVLERNNRLYFLCCNACNSKRSVAVIKKG 304
>sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta
OS=Saccharomyces cerevisiae GN=SUI3 PE=1 SV=2
Length = 285
Score = 192 bits (486), Expect = 6e-048
Identities = 118/255 (46%), Positives = 150/255 (58%), Gaps = 27/255 (10%)
Frame = +2
Query: 158 KKKKKKKVVLQDPIEEPTESPAEPSDSLPANDGGLDGPSFGTKKKKKKKPVESS--SLDD 331
KKKKK K V D E+ EP+D + G L + KKKKKK +SS + +
Sbjct: 50 KKKKKSKSVSAD-----AEAEKEPTDDIAEALGEL------SLKKKKKKTKDSSVDAFEK 98
Query: 332 ESVDAPEDLEEHPNEEEEAEGIDLQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL 511
E A D + ++E QQ+ P Y ELL R FNILR NNPEL
Sbjct: 99 ELAKAGLDNVDAESKEGTPSANSSIQQEVGLP---------YSELLSRFFNILRTNNPEL 149
Query: 512 AGDRRRTVMR--PPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQ 685
AGDR R PP LR+G KKT+F N D+ + +HR P+H++ +L AELGTSGS+DGQ
Sbjct: 150 AGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQ 208
Query: 686 QRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE--NRLFFFRCEKCGSGRSV 859
+RLV+KG+F K E +LRRY+ EYV C CKS +T L +E NRLFF C+ CGS RSV
Sbjct: 209 KRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSV 268
Query: 860 AQIKAGFVARVGRRK 904
+ IK GF A VG+R+
Sbjct: 269 SSIKTGFQATVGKRR 283
>sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 subunit 2
OS=Caenorhabditis elegans GN=K04G2.1 PE=3 SV=4
Length = 250
Score = 178 bits (450), Expect = 9e-044
Identities = 80/157 (50%), Positives = 115/157 (73%)
Frame = +2
Query: 431 EGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKT 610
+G+ DY Y+E L V+ ++++ NP+ AGD+++ ++ P+V R G+KKT F NF+++C+
Sbjct: 81 KGAWPDYTYEEALTLVYQVMKDKNPDFAGDKKKFAIKLPEVARAGSKKTAFSNFLEICRL 140
Query: 611 MHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPD 790
M RQ HV+ FLLAELGT+GS+DG L+VKGR+ K FE +LR+Y+ EYV+C CKSP+
Sbjct: 141 MKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFESVLRKYIKEYVMCHTCKSPE 200
Query: 791 TILSKENRLFFFRCEKCGSGRSVAQIKAGFVARVGRR 901
T L+K+ RLFF +C CGS SV IK+GF A VG+R
Sbjct: 201 TQLTKDTRLFFLQCTNCGSRCSVTAIKSGFKAVVGKR 237
>sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit beta
OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
GN=eIF2B PE=3 SV=1
Length = 142
Score = 102 bits (252), Expect = 8e-021
Identities = 48/133 (36%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Frame = +2
Query: 449 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 628
Y ++ LL + + E PE + PP V+ +T+ NF+D+ + M+R P
Sbjct: 8 YDFERLLDKAY----EELPENVKSHKSRFEVPPAVVTIAGNRTIIENFVDIAEAMNRDPS 63
Query: 629 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 808
H++ F+L E+ T+G+L+G +R++++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 64 HLLKFILREVATAGTLEG-RRVILQGRFTPYLIANKLKKYLKEYVICPVCGSPDTKIIKR 122
Query: 809 NRLFFFRCEKCGS 847
+R +F +CE CG+
Sbjct: 123 DRFYFLKCEACGA 135
>sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit beta OS=Pyrococcus
horikoshii GN=eif2b PE=3 SV=1
Length = 140
Score = 100 bits (248), Expect = 2e-020
Identities = 52/133 (39%), Positives = 82/133 (61%), Gaps = 5/133 (3%)
Frame = +2
Query: 449 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 628
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 629 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 808
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 809 NRLFFFRCEKCGS 847
+R +F +CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit beta OS=Pyrococcus
abyssi GN=eif2b PE=3 SV=1
Length = 140
Score = 99 bits (246), Expect = 4e-020
Identities = 51/133 (38%), Positives = 82/133 (61%), Gaps = 5/133 (3%)
Frame = +2
Query: 449 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 628
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 629 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 808
H++ FLL E+ T+G+L+G +R+V++GRF P +++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKIKKYIKEYVICPVCGSPDTKIIKR 120
Query: 809 NRLFFFRCEKCGS 847
+R +F +CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit beta
OS=Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
GN=eIF2B PE=3 SV=1
Length = 204
Score = 99 bits (244), Expect = 7e-020
Identities = 52/116 (44%), Positives = 69/116 (59%), Gaps = 2/116 (1%)
Frame = +2
Query: 527 RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKG 706
R VM ++ EG K TV NF D+ +++R DH M F+L ELGT+G +DG R V G
Sbjct: 25 RFVMPKAKIYIEG-KTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDG-NRAVFNG 82
Query: 707 RFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGRSVAQIKA 874
+F F+ IL YV +YVIC C PDT L K++R+ CE CGS R + + KA
Sbjct: 83 KFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGSKRPIRKRKA 138
>sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit beta OS=Pyrococcus
furiosus GN=eif2b PE=1 SV=1
Length = 140
Score = 98 bits (242), Expect = 1e-019
Identities = 52/133 (39%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Frame = +2
Query: 449 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 628
Y Y++LL + + L EN + + R + V EG KT+ NF D+ ++R P
Sbjct: 6 YDYEKLLEKAYQELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIADALNRDPQ 61
Query: 629 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 808
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-RRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 809 NRLFFFRCEKCGS 847
+R F +CE CG+
Sbjct: 121 DRFHFLKCEACGA 133
>sp|Q5V323|IF2B_HALMA Translation initiation factor 2 subunit beta OS=Haloarcula
marismortui GN=eif2B PE=3 SV=1
Length = 134
Score = 92 bits (226), Expect = 8e-018
Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Frame = +2
Query: 494 ENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGS 673
E PE+ G R + P + +EG TV+ NF C + R+ DHVM FL +LGTSG
Sbjct: 12 EETPEIDGTSERFEVPDPDIRQEG-NVTVYENFQSTCSRLGREDDHVMKFLQNDLGTSGH 70
Query: 674 LDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFFRCEKCGSGR 853
+D R+ + G F E + YV E+V+C C PDT L +E RCE CG+
Sbjct: 71 IDESGRVRLTGEFDATRIEASIDEYVDEFVLCSECGLPDTQLEREQGALLLRCEACGARS 130
Query: 854 SVAQ 865
+ ++
Sbjct: 131 ATSE 134
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,471,325,924
Number of Sequences: 518415
Number of Extensions: 72471325924
Number of Successful Extensions: 505334272
Number of sequences better than 0.0: 0
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