BLASTX 7.6.2
Query= UN17666 /QuerySize=1059
(1058 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54904|P5CR1_ARATH Pyrroline-5-carboxylate reductase OS=Arabi... 489 2e-137
sp|P17817|P5CR_SOYBN Pyrroline-5-carboxylate reductase OS=Glycin... 412 3e-114
sp|Q04708|P5CR_PEA Pyrroline-5-carboxylate reductase OS=Pisum sa... 397 1e-109
sp|O04016|P5CR_ACTCH Pyrroline-5-carboxylate reductase OS=Actini... 384 5e-106
sp|Q9HH99|P5CR_METAC Pyrroline-5-carboxylate reductase OS=Methan... 231 1e-059
sp|Q5RAQ3|P5CR2_PONAB Pyrroline-5-carboxylate reductase 2 OS=Pon... 221 6e-057
sp|Q96C36|P5CR2_HUMAN Pyrroline-5-carboxylate reductase 2 OS=Hom... 221 8e-057
sp|Q17QJ7|P5CR2_BOVIN Pyrroline-5-carboxylate reductase 2 OS=Bos... 220 2e-056
sp|Q4R6W7|P5CR2_MACFA Pyrroline-5-carboxylate reductase 2 OS=Mac... 218 5e-056
sp|Q6AY23|P5CR2_RAT Pyrroline-5-carboxylate reductase 2 OS=Rattu... 218 9e-056
sp|Q922Q4|P5CR2_MOUSE Pyrroline-5-carboxylate reductase 2 OS=Mus... 217 1e-055
sp|P32322|P5CR1_HUMAN Pyrroline-5-carboxylate reductase 1, mitoc... 216 3e-055
sp|Q5R9X6|P5CR1_PONAB Pyrroline-5-carboxylate reductase 1, mitoc... 216 3e-055
sp|Q58DT4|P5CR1_BOVIN Pyrroline-5-carboxylate reductase 1, mitoc... 215 7e-055
sp|Q922W5|P5CR1_MOUSE Pyrroline-5-carboxylate reductase 1, mitoc... 215 7e-055
sp|Q5SPD7|P5CR3_DANRE Pyrroline-5-carboxylate reductase 3 OS=Dan... 211 6e-054
sp|P0A9L8|P5CR_ECOLI Pyrroline-5-carboxylate reductase OS=Escher... 208 9e-053
sp|P0A9L9|P5CR_SHIFL Pyrroline-5-carboxylate reductase OS=Shigel... 208 9e-053
sp|Q5PQJ6|P5CR3_RAT Pyrroline-5-carboxylate reductase 3 OS=Rattu... 206 3e-052
sp|P74572|P5CR_SYNY3 Pyrroline-5-carboxylate reductase OS=Synech... 201 7e-051
>sp|P54904|P5CR1_ARATH Pyrroline-5-carboxylate reductase OS=Arabidopsis thaliana
GN=PROC1 PE=2 SV=1
Length = 276
Score = 489 bits (1257), Expect = 2e-137
Identities = 255/276 (92%), Positives = 266/276 (96%)
Frame = -3
Query: 1011 METLPISAESFKVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVN 832
ME LPI AESFKVGFIGAGKMAESIARGVVASG+LPPNRI TAVHSNLNRR VFESFGVN
Sbjct: 1 MEILPIPAESFKVGFIGAGKMAESIARGVVASGVLPPNRICTAVHSNLNRRDVFESFGVN 60
Query: 831 VFSSSEEVVKESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQD 652
VFS+SEEVVKESDVVIFSVKPQVVKKA+TE++S L+K+K+LVSVAAGIKL DLQEWSGQD
Sbjct: 61 VFSTSEEVVKESDVVIFSVKPQVVKKAVTELKSKLSKNKILVSVAAGIKLNDLQEWSGQD 120
Query: 651 RFIRVMPNTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSG 472
RFIRVMPNTPAAVGEAASVMSLGT ATEEDGA+VA LFG+VGKIL+ADEKMFDAVTGLSG
Sbjct: 121 RFIRVMPNTPAAVGEAASVMSLGTGATEEDGAIVAMLFGAVGKILKADEKMFDAVTGLSG 180
Query: 471 SGPAYIFLAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPG 292
SGPAYIFLAIEALADGGVAAGLPRELAL LASQTVLGAATMVSKTGKHPGVLKDDVTSPG
Sbjct: 181 SGPAYIFLAIEALADGGVAAGLPRELALSLASQTVLGAATMVSKTGKHPGVLKDDVTSPG 240
Query: 291 GTTIAGVHELEKGSFRATLMNAVVAAANRSRELSQS 184
GTTIAGVHELEKGSFRATLMNAVVAAA RSRELSQS
Sbjct: 241 GTTIAGVHELEKGSFRATLMNAVVAAAKRSRELSQS 276
>sp|P17817|P5CR_SOYBN Pyrroline-5-carboxylate reductase OS=Glycine max PE=2
SV=1
Length = 274
Score = 412 bits (1057), Expect = 3e-114
Identities = 208/274 (75%), Positives = 240/274 (87%)
Frame = -3
Query: 1011 METLPISAESFKVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVN 832
ME PI AES+ +GFIGAGKMAESIARG V SG+LPP+RI TAVH NL RR FESFGV
Sbjct: 1 MEIFPIPAESYTLGFIGAGKMAESIARGAVRSGVLPPSRIRTAVHFNLARRGAFESFGVT 60
Query: 831 VFSSSEEVVKESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQD 652
V S+++VV+ESDVV+ SVKPQ+VK ++++ LTK K+LVSVAAG KLKDLQEW+G D
Sbjct: 61 VLPSNDDVVRESDVVVLSVKPQLVKDVVSKLTPLLTKHKLLVSVAAGTKLKDLQEWAGND 120
Query: 651 RFIRVMPNTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSG 472
RFIRVMPNTPAAVG+AASVMSLG +ATEEDG ++A+LFGS+GKI +A+EK FDA+TGLSG
Sbjct: 121 RFIRVMPNTPAAVGQAASVMSLGGSATEEDGNIIAQLFGSIGKIWKAEEKYFDAITGLSG 180
Query: 471 SGPAYIFLAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPG 292
SGPAY++LAIEALADGGVAAGLPR+L+L LASQTVLGAA+MVS+TGKHPG LKDDVTSPG
Sbjct: 181 SGPAYVYLAIEALADGGVAAGLPRDLSLSLASQTVLGAASMVSQTGKHPGQLKDDVTSPG 240
Query: 291 GTTIAGVHELEKGSFRATLMNAVVAAANRSRELS 190
GTTI G+HELE G FR TLMNAVVAAA RSRELS
Sbjct: 241 GTTITGIHELENGGFRGTLMNAVVAAAKRSRELS 274
>sp|Q04708|P5CR_PEA Pyrroline-5-carboxylate reductase OS=Pisum sativum GN=PROC
PE=2 SV=1
Length = 273
Score = 397 bits (1018), Expect = 1e-109
Identities = 203/273 (74%), Positives = 239/273 (87%), Gaps = 1/273 (0%)
Frame = -3
Query: 1008 ETLPISAESFKVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNV 829
E LPI ++S+ +GFIGAGKMAESIA+G SG+LP +RI TA HSN +RR FES G+ V
Sbjct: 2 EILPILSDSYTLGFIGAGKMAESIAKGASRSGVLPSSRIVTA-HSNPSRRAAFESIGITV 60
Query: 828 FSSSEEVVKESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQDR 649
SS+++VV+ S+VV+FSVKPQ+VK + +++ LTKDK+LVSVAAGIKLKDLQEW+G +R
Sbjct: 61 LSSNDDVVRASNVVVFSVKPQLVKDVVLKLKPLLTKDKLLVSVAAGIKLKDLQEWAGHER 120
Query: 648 FIRVMPNTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGS 469
FIRVMPNTPAAVG+AASVMSLG AATEED L+++LFGS+GKI +AD+K FDA+TGLSGS
Sbjct: 121 FIRVMPNTPAAVGQAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKFFDAITGLSGS 180
Query: 468 GPAYIFLAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGG 289
GPAYI+LAIEALADGGVAAGLPR+LAL LASQTVLGAA+M + +GKHPG LKDDVTSPGG
Sbjct: 181 GPAYIYLAIEALADGGVAAGLPRDLALSLASQTVLGAASMATLSGKHPGQLKDDVTSPGG 240
Query: 288 TTIAGVHELEKGSFRATLMNAVVAAANRSRELS 190
TTIAGVHELEKG FR TLMNAVVAAA RSRELS
Sbjct: 241 TTIAGVHELEKGGFRGTLMNAVVAAAKRSRELS 273
>sp|O04016|P5CR_ACTCH Pyrroline-5-carboxylate reductase OS=Actinidia chinensis
PE=2 SV=1
Length = 278
Score = 384 bits (986), Expect = 5e-106
Identities = 192/270 (71%), Positives = 233/270 (86%), Gaps = 1/270 (0%)
Frame = -3
Query: 1002 LPISAESFKVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNVFS 823
+PI +++K+GFIGAGKMAESIARGVV SG+LP +RI TA H RR+ FESFGV V
Sbjct: 7 VPIPTDTYKLGFIGAGKMAESIARGVVKSGVLPASRIRTA-HLGSARREAFESFGVKVLD 65
Query: 822 SSEEVVKESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQDRFI 643
+++VV++SDV+IFSVKPQ+VK+ + ++R L++ ++LVS+ AG+KLK+L++W+G RFI
Sbjct: 66 RNDQVVEDSDVIIFSVKPQIVKEVVLQLRPLLSEKQLLVSIVAGVKLKELEDWAGHSRFI 125
Query: 642 RVMPNTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGP 463
RVMPNTPAAVGEAASVMSLG AT EDG L+ KLFG++GKI +ADEK+FDAVTGLSGSGP
Sbjct: 126 RVMPNTPAAVGEAASVMSLGATATGEDGELITKLFGAIGKIWKADEKLFDAVTGLSGSGP 185
Query: 462 AYIFLAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTT 283
AYIFLAIEALADGGVAAGLPRELALGLASQTVLGAA+MV++ GKHPG LKDDV S GGTT
Sbjct: 186 AYIFLAIEALADGGVAAGLPRELALGLASQTVLGAASMVARGGKHPGQLKDDVASAGGTT 245
Query: 282 IAGVHELEKGSFRATLMNAVVAAANRSREL 193
IAG+HELEKG FR TLMNAVV+A RS+E+
Sbjct: 246 IAGIHELEKGGFRGTLMNAVVSATKRSQEI 275
>sp|Q9HH99|P5CR_METAC Pyrroline-5-carboxylate reductase OS=Methanosarcina
acetivorans GN=proC PE=3 SV=1
Length = 270
Score = 231 bits (587), Expect = 1e-059
Identities = 119/268 (44%), Positives = 176/268 (65%), Gaps = 1/268 (0%)
Frame = -3
Query: 987 ESFKVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNVFSSSEEV 808
E+ K+GFIGAGKM ++ +G + +G++ P I + + + G+ V + + +
Sbjct: 2 ENQKIGFIGAGKMGSALMQGTIKAGIVTPENIGASDVYEPFLKDLQAKLGIRVSTDNAVI 61
Query: 807 VKESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQ-DRFIRVMP 631
V+ESD++I +VKPQ + ++ +++ +T +K+++S+AAG+ L ++ + R +RVMP
Sbjct: 62 VRESDILILAVKPQTLSSVLSNLKNEITSEKLVISIAAGVPLSTYEDALLEGTRVVRVMP 121
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
N A V EAAS ++ G AT ED ++F +VG ++ E + DAVTGLSGSGPA+IF
Sbjct: 122 NIAATVSEAASGIAPGKNATPEDLKAALEIFSAVGTAVQVPESLMDAVTGLSGSGPAFIF 181
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
IEA+ADG V G+ R+ AL LA+QTVLGAA M +TG HPG LKD VTSP GTTI G+
Sbjct: 182 PVIEAMADGAVLEGMDRKSALTLAAQTVLGAAKMALETGMHPGELKDMVTSPAGTTIQGI 241
Query: 270 HELEKGSFRATLMNAVVAAANRSRELSQ 187
H LE+ RA MNAV+ A+ RS+EL +
Sbjct: 242 HSLEEAGIRAAFMNAVIRASERSKELGK 269
>sp|Q5RAQ3|P5CR2_PONAB Pyrroline-5-carboxylate reductase 2 OS=Pongo abelii
GN=PYCR2 PE=2 SV=1
Length = 320
Score = 221 bits (563), Expect = 6e-057
Identities = 122/266 (45%), Positives = 171/266 (64%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNR-ISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++ARG A+G+L ++ I+++ NL GVN+ S++E VK
Sbjct: 3 VGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + + IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADVQAGHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DAVTGLSGSGPAY F
Sbjct: 123 NTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
+A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HP LKD+V SPGG TI +
Sbjct: 183 MALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HFLESGGFRSLLINAVEASCIRTREL 268
>sp|Q96C36|P5CR2_HUMAN Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens
GN=PYCR2 PE=1 SV=1
Length = 320
Score = 221 bits (562), Expect = 8e-057
Identities = 122/266 (45%), Positives = 171/266 (64%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNR-ISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++ARG A+G+L ++ I+++ NL GVN+ S++E VK
Sbjct: 3 VGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + + IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DAVTGLSGSGPAY F
Sbjct: 123 NTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
+A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HP LKD+V SPGG TI +
Sbjct: 183 MALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HFLESGGFRSLLINAVEASCIRTREL 268
>sp|Q17QJ7|P5CR2_BOVIN Pyrroline-5-carboxylate reductase 2 OS=Bos taurus
GN=PYCR2 PE=2 SV=1
Length = 320
Score = 220 bits (559), Expect = 2e-056
Identities = 121/266 (45%), Positives = 172/266 (64%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNR-ISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++ARG A+G+L ++ I+++ +L GVN+ S++E V+
Sbjct: 3 VGFIGAGQLACALARGFTAAGILSAHKIIASSPEMDLPTVSALRKMGVNLTRSNKETVRH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + + IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DAVTGLSGSGPAY F
Sbjct: 123 NTPVLVREGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
+A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HPG LKD+V SPGG TI +
Sbjct: 183 MALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPGQLKDNVCSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HFLESGGFRSLLINAVEASCIRTREL 268
>sp|Q4R6W7|P5CR2_MACFA Pyrroline-5-carboxylate reductase 2 OS=Macaca
fascicularis GN=PYCR2 PE=2 SV=1
Length = 320
Score = 218 bits (555), Expect = 5e-056
Identities = 120/266 (45%), Positives = 171/266 (64%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNR-ISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VG IGAG++A ++ARG A+G++ ++ I+++ NL GVN+ S++E VK
Sbjct: 3 VGIIGAGQLAYALARGFTAAGIVSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + + IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V ++GT A EDG L+ +L SVG +E + DAVTGLSGSGPAY F
Sbjct: 123 NTPVVVREGATVYAMGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
+A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HP LKD+V SPGG TI +
Sbjct: 183 MALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HFLESGGFRSLLINAVEASCIRTREL 268
>sp|Q6AY23|P5CR2_RAT Pyrroline-5-carboxylate reductase 2 OS=Rattus norvegicus
GN=Pycr2 PE=2 SV=1
Length = 320
Score = 218 bits (553), Expect = 9e-056
Identities = 118/266 (44%), Positives = 172/266 (64%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNR-ISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++ARG A+G+L ++ I+++ +L GVN+ S+++ V+
Sbjct: 3 VGFIGAGQLACALARGFTAAGVLSAHKIIASSPEMDLPTVSALRKMGVNLTRSNKDTVRH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + + ++VS AAG+ + K L + + IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADVQERHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DA+TGLSGSGPAY F
Sbjct: 123 NTPVVVREGATVYATGTHALVEDGKLLEQLMSSVGFCTEVEEDLIDAITGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
+A++ALADGGV G+PR LA+ L +Q +LGAA M+ + HPG LKD+V SPGG TI +
Sbjct: 183 MALDALADGGVKMGVPRRLAVRLGAQALLGAAKMLLDSEDHPGQLKDNVCSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HFLESGGFRSLLINAVEASCIRTREL 268
>sp|Q922Q4|P5CR2_MOUSE Pyrroline-5-carboxylate reductase 2 OS=Mus musculus
GN=Pycr2 PE=2 SV=1
Length = 320
Score = 217 bits (551), Expect = 1e-055
Identities = 118/266 (44%), Positives = 172/266 (64%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNR-ISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++ARG A+G+L ++ I+++ +L GVN+ S+++ V+
Sbjct: 3 VGFIGAGQLACALARGFTAAGVLSAHKIIASSPDMDLPTVSALRRMGVNLTRSNKDTVRH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + + ++VS AAG+ + K L + + IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADVQERHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DA+TGLSGSGPAY F
Sbjct: 123 NTPVVVREGATVYATGTHALVEDGKLLEQLMSSVGFCTEVEEDLIDAITGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
+A++ALADGGV G+PR LA+ L +Q +LGAA M+ + HPG LKD+V SPGG TI +
Sbjct: 183 MALDALADGGVKMGVPRRLAVRLGAQALLGAAKMLLDSEDHPGQLKDNVCSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HFLESGGFRSLLINAVEASCIRTREL 268
>sp|P32322|P5CR1_HUMAN Pyrroline-5-carboxylate reductase 1, mitochondrial
OS=Homo sapiens GN=PYCR1 PE=1 SV=2
Length = 319
Score = 216 bits (548), Expect = 3e-055
Identities = 119/266 (44%), Positives = 170/266 (63%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNRI-STAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++A+G A+G+L ++I +++ +L GV + ++E V+
Sbjct: 3 VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + R IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DAVTGLSGSGPAY F
Sbjct: 123 NTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HPG LKD+V+SPGG TI +
Sbjct: 183 TALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HVLESGGFRSLLINAVEASCIRTREL 268
>sp|Q5R9X6|P5CR1_PONAB Pyrroline-5-carboxylate reductase 1, mitochondrial
OS=Pongo abelii GN=PYCR1 PE=2 SV=1
Length = 319
Score = 216 bits (548), Expect = 3e-055
Identities = 119/266 (44%), Positives = 170/266 (63%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNRI-STAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++A+G A+G+L ++I +++ +L GV + ++E V+
Sbjct: 3 VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + R IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DAVTGLSGSGPAY F
Sbjct: 123 NTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HPG LKD+V+SPGG TI +
Sbjct: 183 TALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+NAV A+ R+REL
Sbjct: 243 HVLESGGFRSLLINAVEASCIRTREL 268
>sp|Q58DT4|P5CR1_BOVIN Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Bos
taurus GN=PYCR1 PE=2 SV=1
Length = 320
Score = 215 bits (545), Expect = 7e-055
Identities = 117/266 (43%), Positives = 169/266 (63%), Gaps = 5/266 (1%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNRI-STAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
VGFIGAG++A ++A+G A+G++ ++I +++ +L GVN+ ++E V+
Sbjct: 3 VGFIGAGQLAFALAKGFTAAGVVAAHKIMASSPDMDLATVSALRKMGVNLTHHNKETVQH 62
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVMP 631
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + + IR M
Sbjct: 63 SDVLFLAVKPHIIPFILDEIAANIEARHIVVSCAAGVTISSIEKKLTAFQPAPKVIRCMT 122
Query: 630 NTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIF 451
NTP V E A+V + GT A EDG L+ +L SVG +E + DAVTGLSGSGPAY F
Sbjct: 123 NTPVVVREGATVYATGTHAQVEDGRLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAF 182
Query: 450 LAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGV 271
A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HPG LKD+V SPGG TI +
Sbjct: 183 TALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPGQLKDNVCSPGGATIHAL 242
Query: 270 HELEKGSFRATLMNAVVAAANRSREL 193
H LE G FR+ L+ AV A+ R+REL
Sbjct: 243 HVLESGGFRSLLIKAVEASCTRTREL 268
>sp|Q922W5|P5CR1_MOUSE Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Mus
musculus GN=Pycr1 PE=1 SV=1
Length = 309
Score = 215 bits (545), Expect = 7e-055
Identities = 120/267 (44%), Positives = 170/267 (63%), Gaps = 7/267 (2%)
Frame = -3
Query: 975 VGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQV--FESFGVNVFSSSEEVVK 802
VGFIGAG++A ++A+G A+G+L ++I A ++++ V GVN+ ++E V+
Sbjct: 3 VGFIGAGQLAFALAKGFTAAGVLAAHKI-MASSPDMDQATVSALRKIGVNLTPHNKETVR 61
Query: 801 ESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKL----KDLQEWSGQDRFIRVM 634
SDV+ +VKP ++ + E+ + + ++VS AAG+ + K L + + IR M
Sbjct: 62 HSDVLFLAVKPHIIPFILDEIGANIEDRHIVVSCAAGVTINSIEKKLTAFQPAPKVIRCM 121
Query: 633 PNTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYI 454
NTP V E +V + GT A EDG LV +L GSVG +E + DAVTGLSGSGPAY
Sbjct: 122 TNTPVVVREGVTVYATGTHAQVEDGRLVEQLMGSVGFCTEVEEDLIDAVTGLSGSGPAYA 181
Query: 453 FLAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAG 274
F A++ALADGGV GLPR LA+ L +Q +LGAA M+ + +HP LKD+V SPGG TI
Sbjct: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPSQLKDNVCSPGGATIHA 241
Query: 273 VHELEKGSFRATLMNAVVAAANRSREL 193
+H LE G FR+ L+NAV A+ R+REL
Sbjct: 242 LHVLESGGFRSLLINAVEASCIRTREL 268
>sp|Q5SPD7|P5CR3_DANRE Pyrroline-5-carboxylate reductase 3 OS=Danio rerio
GN=pycrl PE=2 SV=1
Length = 288
Score = 211 bits (537), Expect = 6e-054
Identities = 114/263 (43%), Positives = 167/263 (63%), Gaps = 2/263 (0%)
Frame = -3
Query: 978 KVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
K+GFIGAG MA +A+G++ASG +PP+ I + S +N F+ GV+V S+ EVV
Sbjct: 20 KIGFIGAGNMAFGVAQGIIASGKVPPSNIIISAPS-MNNLPRFKEKGVSVTHSNHEVVGG 78
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQE-WSGQDRFIRVMPNTP 622
S ++ +VKP ++ + + E+ +TK+ ++VS+AAGI + L+E IR+MPN P
Sbjct: 79 SRLIFLAVKPHIIPQVLKEISQEVTKEHIIVSMAAGITIATLEELLPAGTHVIRIMPNLP 138
Query: 621 AAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIFLAI 442
+ E A ++S G+ A E++ L+ L G G + E DA GLSGSG A++++
Sbjct: 139 CMLLEGALLLSCGSHAGEQEETLLKTLLGPCGLVEFGPESWIDAHVGLSGSGVAFVYVFA 198
Query: 441 EALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGVHEL 262
EALADG V G+P LA +A+QT+LGA ++ +GK P LK +V +PGGTTI G+H L
Sbjct: 199 EALADGAVKMGMPSTLARRIAAQTILGAGVLLRDSGKLPAELKAEVCTPGGTTIHGIHAL 258
Query: 261 EKGSFRATLMNAVVAAANRSREL 193
EKG FRA + AV AA+ R+REL
Sbjct: 259 EKGGFRAAAIGAVEAASERAREL 281
>sp|P0A9L8|P5CR_ECOLI Pyrroline-5-carboxylate reductase OS=Escherichia coli
(strain K12) GN=proC PE=1 SV=1
Length = 269
Score = 208 bits (527), Expect = 9e-053
Identities = 112/266 (42%), Positives = 161/266 (60%), Gaps = 1/266 (0%)
Frame = -3
Query: 978 KVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
K+GFIG G M ++I G++ASG + P +I S + + FG+N S++EV +
Sbjct: 4 KIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEVAQI 63
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQDR-FIRVMPNTP 622
+D++ +VKP ++ K ++E+ S+L KD ++VS+AAG+ L L G DR IR MPNTP
Sbjct: 64 ADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTP 123
Query: 621 AAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIFLAI 442
A V + ++ T ED A V +F G+ E M V G+SGS PAY+F+ I
Sbjct: 124 ALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFMFI 183
Query: 441 EALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGVHEL 262
EA+AD V G+PR A A+Q V+G+A MV +TG+HPG LKD V SPGGTTI V L
Sbjct: 184 EAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVRVL 243
Query: 261 EKGSFRATLMNAVVAAANRSRELSQS 184
E+ FRA ++ A+ +S +LS+S
Sbjct: 244 EEKGFRAAVIEAMTKCMEKSEKLSKS 269
>sp|P0A9L9|P5CR_SHIFL Pyrroline-5-carboxylate reductase OS=Shigella flexneri
GN=proC PE=3 SV=1
Length = 269
Score = 208 bits (527), Expect = 9e-053
Identities = 112/266 (42%), Positives = 161/266 (60%), Gaps = 1/266 (0%)
Frame = -3
Query: 978 KVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNVFSSSEEVVKE 799
K+GFIG G M ++I G++ASG + P +I S + + FG+N S++EV +
Sbjct: 4 KIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEVAQI 63
Query: 798 SDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQDR-FIRVMPNTP 622
+D++ +VKP ++ K ++E+ S+L KD ++VS+AAG+ L L G DR IR MPNTP
Sbjct: 64 ADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTP 123
Query: 621 AAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIFLAI 442
A V + ++ T ED A V +F G+ E M V G+SGS PAY+F+ I
Sbjct: 124 ALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFMFI 183
Query: 441 EALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGVHEL 262
EA+AD V G+PR A A+Q V+G+A MV +TG+HPG LKD V SPGGTTI V L
Sbjct: 184 EAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVRVL 243
Query: 261 EKGSFRATLMNAVVAAANRSRELSQS 184
E+ FRA ++ A+ +S +LS+S
Sbjct: 244 EEKGFRAAVIEAMTKCMEKSEKLSKS 269
>sp|Q5PQJ6|P5CR3_RAT Pyrroline-5-carboxylate reductase 3 OS=Rattus norvegicus
GN=Pycrl PE=2 SV=1
Length = 274
Score = 206 bits (522), Expect = 3e-052
Identities = 112/269 (41%), Positives = 167/269 (62%), Gaps = 2/269 (0%)
Frame = -3
Query: 990 AESFKVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNVFSSSEE 811
+E +VGF+GAG+MAE+IA+G++ +G + ++ + ++ N F + G S+ E
Sbjct: 6 SEPRRVGFVGAGRMAEAIAQGLIRAGKVEAKQVLASAPTDKNLCH-FRALGCQTTHSNHE 64
Query: 810 VVKESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQE-WSGQDRFIRVM 634
V++ +VIF+ KPQV+ + EV +T + ++VSVAAGI L ++E + R +RV
Sbjct: 65 VLQNCPLVIFATKPQVLPAVLAEVAPVVTTEHIIVSVAAGISLSSMEELLPPKTRVLRVS 124
Query: 633 PNTPAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYI 454
PN P V E A VM+ G A ED L+ L + G+ + E D TGLSGSG A++
Sbjct: 125 PNLPCVVQEGAMVMTRGHHAGNEDAKLLQNLLEACGQCIEVPESYVDIHTGLSGSGVAFV 184
Query: 453 FLAIEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAG 274
EALA+G + G+P +LA +A+QT+LG A M+ + GKHP L+ DV +P GTTI G
Sbjct: 185 CTFSEALAEGAIKMGMPSDLAHRIAAQTLLGTAKMLQQEGKHPAQLRTDVLTPAGTTIHG 244
Query: 273 VHELEKGSFRATLMNAVVAAANRSRELSQ 187
+H LE+G FRA M+AV AA R++ELS+
Sbjct: 245 LHALEQGGFRAAAMSAVEAATCRAKELSK 273
>sp|P74572|P5CR_SYNY3 Pyrroline-5-carboxylate reductase OS=Synechocystis sp.
(strain PCC 6803) GN=proC PE=3 SV=1
Length = 267
Score = 201 bits (511), Expect = 7e-051
Identities = 109/266 (40%), Positives = 159/266 (59%), Gaps = 1/266 (0%)
Frame = -3
Query: 984 SFKVGFIGAGKMAESIARGVVASGMLPPNRISTAVHSNLNRRQVFESFGVNVFSSSEEVV 805
S ++G IG G MAE+I ++A P I R + +++ V V ++E
Sbjct: 2 SIQLGIIGGGVMAEAILARLIAEKTYAPEEIIVGEPHGARRDYLQKTYQVRVSPDNQEAA 61
Query: 804 KESDVVIFSVKPQVVKKAITEVRSTLTKDKVLVSVAAGIKLKDLQEWSGQDRFIRVMPNT 625
S+V++ +VKPQV+ + + + + +++S+ AG+ L+ +Q+ IR MPNT
Sbjct: 62 NVSEVLLLAVKPQVLDRVLASLAGGANR-PLVISILAGVSLQRIQKGFPDHAIIRAMPNT 120
Query: 624 PAAVGEAASVMSLGTAATEEDGALVAKLFGSVGKILRADEKMFDAVTGLSGSGPAYIFLA 445
PA VG + ++ + A +F +VG ++ E + DAVTG+SGSGPAY+ L
Sbjct: 121 PATVGAGMTAIAANKMVEPDQLAKAKAIFSAVGNVVEVPENLMDAVTGVSGSGPAYVALM 180
Query: 444 IEALADGGVAAGLPRELALGLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGVHE 265
IEALADGGV AGLPR +A LA QTVLG A ++ +T +HP +KD VTSPGGTTIAGV
Sbjct: 181 IEALADGGVLAGLPRAIAQKLALQTVLGTAELIKETEEHPAQIKDKVTSPGGTTIAGVAV 240
Query: 264 LEKGSFRATLMNAVVAAANRSRELSQ 187
LEK FR+ ++ AV AA RS+EL +
Sbjct: 241 LEKMGFRSAIIEAVRAAYRRSQELGK 266
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,471,325,924
Number of Sequences: 518415
Number of Extensions: 72471325924
Number of Successful Extensions: 505334272
Number of sequences better than 0.0: 0
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