BLASTX 7.6.2
Query= UN17729 /QuerySize=1101
(1100 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 ... 414 9e-115
sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 ... 389 2e-107
sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 ... 370 1e-101
sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 ... 241 8e-063
sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 ... 241 8e-063
sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 ... 241 1e-062
sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 ... 239 3e-062
sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 ... 238 7e-062
sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 ... 236 3e-061
sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation ... 231 6e-060
sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2... 219 4e-056
sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 ... 218 9e-056
sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 ... 194 1e-048
sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 ... 179 3e-044
sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit bet... 103 3e-021
sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit bet... 102 7e-021
sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit bet... 101 1e-020
sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit bet... 100 2e-020
sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit bet... 99 4e-020
sp|Q5V323|IF2B_HALMA Translation initiation factor 2 subunit bet... 93 3e-018
>sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 subunit beta
OS=Arabidopsis thaliana GN=EMB1401 PE=2 SV=3
Length = 268
Score = 414 bits (1062), Expect = 9e-115
Identities = 215/271 (79%), Positives = 236/271 (87%), Gaps = 10/271 (3%)
Frame = -3
Query: 999 LKEVKDEQE-LAPFDPTKKKKKKKAVIQDPIEEPTE-SPAEPSDSLPASDGGLDGPSFGT 826
+ E+++EQE LAPFDP+KKKKKKK VIQ+P+E+ E S E SDSLP +D GL+ SF
Sbjct: 5 INEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVND-GLES-SFTG 62
Query: 825 KKKKKKKPVETNSLDEETVDAPEDLEEHPNEEEEA-EGIDLQQQQQQQRYPWEGSDRDYI 649
KKKKKKP E++ L+ E+VDA EDL+E N+E+E EGI L QQRYPWEGS+RDYI
Sbjct: 63 MKKKKKKPTESSLLNNESVDAGEDLDEIANDEQEGEEGIVL-----QQRYPWEGSERDYI 117
Query: 648 YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 469
YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV
Sbjct: 118 YDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 177
Query: 468 MNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENR 289
M +LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRY+T+YVICLGCKSPDTILSKENR
Sbjct: 178 MQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENR 237
Query: 288 LFFLRCEKCGSGRSVAQIKAGFVARVGRRKT 196
LFFLRCEKCGS RSVA IK GFVARV RRKT
Sbjct: 238 LFFLRCEKCGSQRSVAPIKTGFVARVSRRKT 268
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 subunit beta
OS=Malus domestica PE=2 SV=2
Length = 271
Score = 389 bits (999), Expect = 2e-107
Identities = 200/266 (75%), Positives = 220/266 (82%), Gaps = 8/266 (3%)
Frame = -3
Query: 993 EVKDE--QELAPFDPTKKKKKKKAVIQDPIEEPTESPAEPSDSLPASDGGLDGPSFGTKK 820
EVKDE ++APFDPTKKKKKK+ VIQD ++ AE +++ AS+G +F K
Sbjct: 8 EVKDEVVADIAPFDPTKKKKKKEVVIQDTTDDSVGKLAEKAEACTASEG--QESTFAGLK 65
Query: 819 KKKKKPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSDRDYIYDE 640
KKKKKP+ET+ L+EE+ DA EDL E E+EE EGI L+ YPWEGSDRDY Y+E
Sbjct: 66 KKKKKPIETSILNEESGDAVEDLNERTGEDEEGEGIVLETPS----YPWEGSDRDYTYEE 121
Query: 639 LLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNF 460
LL RVF ILRENNP+LAGDRRRTVMRPPQVLREGTKK VFVNFMDLCKTMHRQPDHVM F
Sbjct: 122 LLDRVFTILRENNPDLAGDRRRTVMRPPQVLREGTKKAVFVNFMDLCKTMHRQPDHVMAF 181
Query: 459 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFF 280
LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYV EYVICLGC+SPDTILSKENRLFF
Sbjct: 182 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVNEYVICLGCQSPDTILSKENRLFF 241
Query: 279 LRCEKCGSGRSVAQIKAGFVARVGRR 202
LRCEKCGSGRSVA KAGF+ARVGRR
Sbjct: 242 LRCEKCGSGRSVAPNKAGFMARVGRR 267
>sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 subunit beta
OS=Triticum aestivum PE=1 SV=1
Length = 270
Score = 370 bits (948), Expect = 1e-101
Identities = 190/267 (71%), Positives = 215/267 (80%), Gaps = 6/267 (2%)
Frame = -3
Query: 999 LKEVKDEQELAPFDPTKKKKKKKAVIQDPIEEPTESPAEPSDSLPASDGGLDGPSFGTKK 820
++ ++ E+APFDPTKKKKKKK VIQDP +E + AE ++ L ++ G SF K
Sbjct: 7 MERKEEATEIAPFDPTKKKKKKKVVIQDPADE-VDKLAEKTEGLSVTESG--EASFVGLK 63
Query: 819 KKKKKPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSDRDYIYDE 640
KKKKK VE + E D + L++ E+E+ EGI L Q YPWEG+DRDY YDE
Sbjct: 64 KKKKKLVELDPSLVEAGDGEDTLDDQVGEDEQGEGIVLGGATQ---YPWEGTDRDYKYDE 120
Query: 639 LLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNF 460
LLGRVFNILRENNP+LAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP+HVM F
Sbjct: 121 LLGRVFNILRENNPDLAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPEHVMMF 180
Query: 459 LLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFF 280
LLAE+GTSGSLDGQQRLV+KGRFAPKNFE ILRRY+ EYVIC GCKSPDTILSKENRLFF
Sbjct: 181 LLAEMGTSGSLDGQQRLVIKGRFAPKNFEAILRRYINEYVICHGCKSPDTILSKENRLFF 240
Query: 279 LRCEKCGSGRSVAQIKAGFVARVGRRK 199
LRCE+CGS RSVA IKAGFVA+VGRRK
Sbjct: 241 LRCEQCGSSRSVAPIKAGFVAQVGRRK 267
>sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 subunit 2
OS=Bos taurus GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 241 bits (614), Expect = 8e-063
Identities = 133/274 (48%), Positives = 178/274 (64%), Gaps = 9/274 (3%)
Frame = -3
Query: 1014 DENNELKEVKDE-QELAPFDPTKKKKKKKAVIQ-DPIEEPTESPAEPSDSLPASDGGLDG 841
+E++ K+ D+ +L F+ KKKKK K + D EE + SD ++ D
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKSKKIFDIDEAEEGIKDLKIESDVQEPAEPEEDL 117
Query: 840 PSFGTKKKKKKKPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSD 661
KKKKKK V+ ++E ++ E LE+ ++++ +GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKVVKFPD-EDEVLEKDEALEDEDSKKD--DGISFSNQTGP---AWAGSE 171
Query: 660 RDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 484
RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 172 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 231
Query: 483 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTIL 304
QP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL
Sbjct: 232 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTIL 291
Query: 303 SKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 202
K+ RL+FL+CE C S SVA IK GF A GRR
Sbjct: 292 QKDTRLYFLQCETCHSRCSVASIKTGFQAVTGRR 325
>sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2
OS=Mus musculus GN=Eif2s2 PE=1 SV=1
Length = 331
Score = 241 bits (614), Expect = 8e-063
Identities = 132/274 (48%), Positives = 179/274 (65%), Gaps = 11/274 (4%)
Frame = -3
Query: 1014 DENNELKEVKDE-QELAPFDPTKKKKKKKAVIQ-DPIEEPTESPAEPSDSLPASDGGLDG 841
+E++ K+ D+ +L F+ KKKKK K + D EE + SD+ ++ D
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIESDAQEPAEPEDDL 117
Query: 840 PSFGTKKKKKKKPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSD 661
KKKKKK V+ ++E ++ E LE+ ++++ +GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKNVKFPE-EDEILEKDEALEDEDSKKD--DGISFSSQT-----AWAGSE 169
Query: 660 RDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 484
RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 170 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 229
Query: 483 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTIL 304
QP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL
Sbjct: 230 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTIL 289
Query: 303 SKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 202
K+ RL+FL+CE C S SVA IK GF A G+R
Sbjct: 290 QKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 323
>sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2
OS=Homo sapiens GN=EIF2S2 PE=1 SV=2
Length = 333
Score = 241 bits (613), Expect = 1e-062
Identities = 133/274 (48%), Positives = 177/274 (64%), Gaps = 9/274 (3%)
Frame = -3
Query: 1014 DENNELKEVKDE-QELAPFDPTKKKKKKKAVIQ-DPIEEPTESPAEPSDSLPASDGGLDG 841
+E+ K+ D+ +L F+ KKKKK K + D EE + SD ++ D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPTEPEDDL 117
Query: 840 PSFGTKKKKKKKPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSD 661
KKKKKK V+ ++E ++ E LE+ N+++ +GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDNKKD--DGISFSNQTGP---AWAGSE 171
Query: 660 RDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 484
RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 172 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 231
Query: 483 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTIL 304
QP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL
Sbjct: 232 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTIL 291
Query: 303 SKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 202
K+ RL+FL+CE C S SVA IK GF A G+R
Sbjct: 292 QKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 subunit 2
OS=Pongo abelii GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 239 bits (609), Expect = 3e-062
Identities = 132/274 (48%), Positives = 176/274 (64%), Gaps = 9/274 (3%)
Frame = -3
Query: 1014 DENNELKEVKDE-QELAPFDPTKKKKKKKAVIQ-DPIEEPTESPAEPSDSLPASDGGLDG 841
+E+ K+ D+ +L F+ KKKKK K + D EE + SD ++ D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIESDVQEPTEPEDDL 117
Query: 840 PSFGTKKKKKKKPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSD 661
KKKKKK V+ ++E ++ E LE+ N+++ +GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDNKKD--DGISFSNQTGP---AWAGSE 171
Query: 660 RDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 484
RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 172 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 231
Query: 483 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTIL 304
QP H++ FLLAELGTSGS+DG +LV+KGRF K E +LRRY+ EYV C C+SPDTIL
Sbjct: 232 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTIL 291
Query: 303 SKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 202
K+ RL+FL+CE C S S A IK GF A G+R
Sbjct: 292 QKDTRLYFLQCETCHSRCSAASIKTGFQAVTGKR 325
>sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 subunit 2
OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
Length = 333
Score = 238 bits (606), Expect = 7e-062
Identities = 135/294 (45%), Positives = 183/294 (62%), Gaps = 11/294 (3%)
Frame = -3
Query: 1068 PLKT---NPSPPKLISVAIMADENNELKEVKDEQELAPFDPTKKKKKKKAVIQ-DPIEEP 901
PL+T P P + V +++ + D +L F+ KKKKK K + D EE
Sbjct: 38 PLETKEVEPEPTEDKDVEADEEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEG 97
Query: 900 TESPAEPSDSLPASDGGLDGPSFGTKKKKKKKPVETNSLDEETVDAPEDLEEHPNEEEEA 721
+ +D ++ D KKKKKK V+ ++E ++ E LE+ ++++
Sbjct: 98 VKDLKIENDVQEPAEPEDDLDIMLGNKKKKKKNVKFPD-EDEILEKDEALEDEDSKKD-- 154
Query: 720 EGIDLQQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLR 544
+GI Q W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R
Sbjct: 155 DGISFSNQTGP---AWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVR 211
Query: 543 EGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGIL 364
GTKKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGRF K E +L
Sbjct: 212 VGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVL 271
Query: 363 RRYVTEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 202
RRY+ EYV C C+SPDTIL K+ RL+FL+CE C S SVA IK GF A G+R
Sbjct: 272 RRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 subunit 2
OS=Drosophila melanogaster GN=eIF-2beta PE=1 SV=1
Length = 312
Score = 236 bits (600), Expect = 3e-061
Identities = 135/269 (50%), Positives = 166/269 (61%), Gaps = 24/269 (8%)
Frame = -3
Query: 987 KDEQELAPFDPTKKKKKKKAVIQDPIEEPTESPAEPSDSLPASDG------GLDGPSFGT 826
+D +L F KKKKKKK D IE P+ D + AS+ LD
Sbjct: 53 EDNLDLESFG-KKKKKKKKPFNMDEIE--AAIPSFGGDDVAASEEPEEEEINLDMDFSMA 109
Query: 825 KKKKKKKPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSDRDYIY 646
KKKKK K E LDE D +D + E +E W GSDRDY Y
Sbjct: 110 KKKKKSKKKE---LDELFADQADDDKSEDKENDE-----------DNSSTWFGSDRDYTY 155
Query: 645 DELLGRVFNILRENNPELAGDRR-RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHV 469
DELL RVF I+ + NP++A R+ + VMRPPQVLR GTKKT F NFMD+ KT+HR P H+
Sbjct: 156 DELLKRVFEIILDKNPDMAAGRKPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHL 215
Query: 468 MNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENR 289
++FLLAELGTSGS+DG Q+L++KGRF PK E +LRRY+ EYV C C+SP+TIL K+ R
Sbjct: 216 LDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQKDTR 275
Query: 288 LFFLRCEKCGSGRSVAQIKAGFVARVGRR 202
LFFL+CE CGS SVA IK+GF A G+R
Sbjct: 276 LFFLQCESCGSRCSVASIKSGFQAVTGKR 304
>sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation factor 2
subunit beta OS=Schizosaccharomyces pombe GN=tif212 PE=1 SV=2
Length = 321
Score = 231 bits (589), Expect = 6e-060
Identities = 131/289 (45%), Positives = 170/289 (58%), Gaps = 34/289 (11%)
Frame = -3
Query: 1050 SPPKLISVAIMADENNELKEVKDEQELAPFDPTKKKKKKKAVIQDPIEEPTESPAEPSDS 871
S K ++ + E +ELK++ F KKKKK K + + S E ++
Sbjct: 59 SSAKDLTTPVTEGEVDELKDM--------FSSMKKKKKSK--------KSSASAEEQTED 102
Query: 870 LPASDGGLDGPSFGTKKKKKKKPVETNSLDEE-----TVDAPEDLEEHPNEEEEAEGIDL 706
+ G LD S KKKKKKK + ++ ++E T DA DL + + E
Sbjct: 103 ITTESGELDFSSM-KKKKKKKKSADLSAFEKELEASSTGDATSDLSKQTFDSE------- 154
Query: 705 QQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKT 526
+ W SDRDY Y ELL R F +LR NNPELAG++R+ + PP V REG KKT
Sbjct: 155 ----NMGEHAWLKSDRDYYYPELLNRFFTLLRTNNPELAGEKRKYTIVPPSVHREG-KKT 209
Query: 525 VFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTE 346
+F N D+ K MHR DHV+ FL AELGTSGS+DG RL++KGRF K E +LRRY+ E
Sbjct: 210 IFANISDISKRMHRSLDHVIQFLFAELGTSGSVDGSSRLIIKGRFQQKQIENVLRRYIVE 269
Query: 345 YVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRRK 199
YV C CKSPDTIL+KENR+FF+ CE CGS RSV IK G+ A++G+RK
Sbjct: 270 YVTCKTCKSPDTILTKENRIFFMTCEACGSVRSVQAIKTGYQAQIGKRK 318
>sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2 subunit 2-like
protein OS=Homo sapiens PE=1 SV=1
Length = 327
Score = 219 bits (556), Expect = 4e-056
Identities = 109/190 (57%), Positives = 139/190 (73%), Gaps = 6/190 (3%)
Frame = -3
Query: 768 DAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL- 592
D E LE+ N+++ +GI Q W GS+RDY Y+ELL RVFNI+RE NP++
Sbjct: 135 DEDEALEDEDNKKD--DGISFSNQTGP---AWAGSERDYTYEELLNRVFNIMREKNPDMV 189
Query: 591 AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQR 412
AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +
Sbjct: 190 AGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQ 249
Query: 411 LVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIK 232
LV+KGRF K E +LRRY+ EYV C C+SPDTIL K+ RL+FL+CE C S SVA IK
Sbjct: 250 LVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDMRLYFLQCETCHSRCSVAIIK 309
Query: 231 AGFVARVGRR 202
GF A +G+R
Sbjct: 310 IGFQAVMGKR 319
>sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 subunit 2
OS=Dictyostelium discoideum GN=eif2s2 PE=3 SV=1
Length = 317
Score = 218 bits (553), Expect = 9e-056
Identities = 114/274 (41%), Positives = 169/274 (61%), Gaps = 14/274 (5%)
Frame = -3
Query: 1032 SVAIMADENNELKEVKDEQELAPFDPTKKKKKKKAVIQDPIEEPTESPAEPSDSLPASDG 853
++A+M+ + +E +E +DE++ +K+KKKKA + E E ++ A D
Sbjct: 40 TLAMMSQQEDE-QEQEDEKK-------EKRKKKKAALLASTEGENSEAIEKLENEGAHDE 91
Query: 852 GLDGPSFGTKKKKKK-KPVETNSLDEETVDAPEDLEEHPNEEEEAEGIDLQQQQ----QQ 688
++ G KKKKKK T + T E E P E+ E++ + Q
Sbjct: 92 DIEAEFMGEKKKKKKSSKSSTTTTTSTTTTTTEPTETEPTEDGESKEKTITTSDGDTFVQ 151
Query: 687 QRYPWEGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFM 508
PW G+DRDY Y EL R++++L+ NNP+L D++RT M+PPQV+REGTKKT++ NF
Sbjct: 152 GTIPWAGTDRDYKYSELTYRIYHLLQANNPDLISDQKRT-MKPPQVMREGTKKTIWANFA 210
Query: 507 DLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLG 328
++C T++R+ +HV N++ AELGT+GS+DG QRLV++GRF E ++R Y++EYV C
Sbjct: 211 EICGTLNRKVEHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQIEIVIRHYISEYVACRN 270
Query: 327 CKSPDTILSKENRLFFLRCEKCGSGRSVAQIKAG 226
CKSP+T+L + NRL+FL C C S RSVA IK G
Sbjct: 271 CKSPNTVLERNNRLYFLCCNACNSKRSVAVIKKG 304
>sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta
OS=Saccharomyces cerevisiae GN=SUI3 PE=1 SV=2
Length = 285
Score = 194 bits (492), Expect = 1e-048
Identities = 117/255 (45%), Positives = 151/255 (59%), Gaps = 25/255 (9%)
Frame = -3
Query: 951 KKKKKKKAVIQDPIEEPTESPAEPSDSLPASDGGLDGPSFGTKKKKKKKPVETNSLDEET 772
KKKKK K+V D E+ EP+D + + G L KKKKK K ++ ++E
Sbjct: 50 KKKKKSKSVSAD-----AEAEKEPTDDIAEALGELS----LKKKKKKTKDSSVDAFEKEL 100
Query: 771 VDAPEDLEEHPNEEEEAEGIDLQQQQQQQRYPWEGSDRDYIYDELLGRVFNILRENNPEL 592
A L+ E +E QQ+ P Y ELL R FNILR NNPEL
Sbjct: 101 AKA--GLDNVDAESKEGTPSANSSIQQEVGLP---------YSELLSRFFNILRTNNPEL 149
Query: 591 AGDRRRTVMR--PPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQ 418
AGDR R PP LR+G KKT+F N D+ + +HR P+H++ +L AELGTSGS+DGQ
Sbjct: 150 AGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQ 208
Query: 417 QRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE--NRLFFLRCEKCGSGRSV 244
+RLV+KG+F K E +LRRY+ EYV C CKS +T L +E NRLFF+ C+ CGS RSV
Sbjct: 209 KRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSV 268
Query: 243 AQIKAGFVARVGRRK 199
+ IK GF A VG+R+
Sbjct: 269 SSIKTGFQATVGKRR 283
>sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 subunit 2
OS=Caenorhabditis elegans GN=K04G2.1 PE=3 SV=4
Length = 250
Score = 179 bits (454), Expect = 3e-044
Identities = 81/157 (51%), Positives = 116/157 (73%)
Frame = -3
Query: 672 EGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKT 493
+G+ DY Y+E L V+ ++++ NP+ AGD+++ ++ P+V R G+KKT F NF+++C+
Sbjct: 81 KGAWPDYTYEEALTLVYQVMKDKNPDFAGDKKKFAIKLPEVARAGSKKTAFSNFLEICRL 140
Query: 492 MHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPD 313
M RQ HV+ FLLAELGT+GS+DG L+VKGR+ K FE +LR+Y+ EYV+C CKSP+
Sbjct: 141 MKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFESVLRKYIKEYVMCHTCKSPE 200
Query: 312 TILSKENRLFFLRCEKCGSGRSVAQIKAGFVARVGRR 202
T L+K+ RLFFL+C CGS SV IK+GF A VG+R
Sbjct: 201 TQLTKDTRLFFLQCTNCGSRCSVTAIKSGFKAVVGKR 237
>sp|C5A2A8|IF2B_THEGJ Translation initiation factor 2 subunit beta
OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
GN=eIF2B PE=3 SV=1
Length = 142
Score = 103 bits (256), Expect = 3e-021
Identities = 49/133 (36%), Positives = 81/133 (60%), Gaps = 5/133 (3%)
Frame = -3
Query: 654 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 475
Y ++ LL + + E PE + PP V+ +T+ NF+D+ + M+R P
Sbjct: 8 YDFERLLDKAY----EELPENVKSHKSRFEVPPAVVTIAGNRTIIENFVDIAEAMNRDPS 63
Query: 474 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 295
H++ F+L E+ T+G+L+G +R++++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 64 HLLKFILREVATAGTLEG-RRVILQGRFTPYLIANKLKKYLKEYVICPVCGSPDTKIIKR 122
Query: 294 NRLFFLRCEKCGS 256
+R +FL+CE CG+
Sbjct: 123 DRFYFLKCEACGA 135
>sp|O58312|IF2B_PYRHO Translation initiation factor 2 subunit beta OS=Pyrococcus
horikoshii GN=eif2b PE=3 SV=1
Length = 140
Score = 102 bits (252), Expect = 7e-021
Identities = 53/133 (39%), Positives = 83/133 (62%), Gaps = 5/133 (3%)
Frame = -3
Query: 654 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 475
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 474 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 295
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 294 NRLFFLRCEKCGS 256
+R +FL+CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|Q9UYR6|IF2B_PYRAB Translation initiation factor 2 subunit beta OS=Pyrococcus
abyssi GN=eif2b PE=3 SV=1
Length = 140
Score = 101 bits (250), Expect = 1e-020
Identities = 52/133 (39%), Positives = 83/133 (62%), Gaps = 5/133 (3%)
Frame = -3
Query: 654 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 475
Y Y++LL + + L EN + + R + V EG KT+ NF D+ + ++R P
Sbjct: 6 YDYEKLLEKAYEELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIAEALNRDPQ 61
Query: 474 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 295
H++ FLL E+ T+G+L+G +R+V++GRF P +++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-KRVVLQGRFTPYLIANKIKKYIKEYVICPVCGSPDTKIIKR 120
Query: 294 NRLFFLRCEKCGS 256
+R +FL+CE CG+
Sbjct: 121 DRFYFLKCEACGA 133
>sp|A2SSW2|IF2B_METLZ Translation initiation factor 2 subunit beta
OS=Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
GN=eIF2B PE=3 SV=1
Length = 204
Score = 100 bits (248), Expect = 2e-020
Identities = 53/116 (45%), Positives = 70/116 (60%), Gaps = 2/116 (1%)
Frame = -3
Query: 576 RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKG 397
R VM ++ EG K TV NF D+ +++R DH M F+L ELGT+G +DG R V G
Sbjct: 25 RFVMPKAKIYIEG-KTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDG-NRAVFNG 82
Query: 396 RFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAQIKA 229
+F F+ IL YV +YVIC C PDT L K++R+ L CE CGS R + + KA
Sbjct: 83 KFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGSKRPIRKRKA 138
>sp|Q8U3I5|IF2B_PYRFU Translation initiation factor 2 subunit beta OS=Pyrococcus
furiosus GN=eif2b PE=1 SV=1
Length = 140
Score = 99 bits (246), Expect = 4e-020
Identities = 53/133 (39%), Positives = 81/133 (60%), Gaps = 5/133 (3%)
Frame = -3
Query: 654 YIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 475
Y Y++LL + + L EN + + R + V EG KT+ NF D+ ++R P
Sbjct: 6 YDYEKLLEKAYQELPEN---VKHHKSRFEVPGALVTIEG-NKTIIENFKDIADALNRDPQ 61
Query: 474 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKE 295
H++ FLL E+ T+G+L+G +R+V++GRF P L++Y+ EYVIC C SPDT + K
Sbjct: 62 HLLKFLLREIATAGTLEG-RRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKR 120
Query: 294 NRLFFLRCEKCGS 256
+R FL+CE CG+
Sbjct: 121 DRFHFLKCEACGA 133
>sp|Q5V323|IF2B_HALMA Translation initiation factor 2 subunit beta OS=Haloarcula
marismortui GN=eif2B PE=3 SV=1
Length = 134
Score = 93 bits (230), Expect = 3e-018
Identities = 47/124 (37%), Positives = 66/124 (53%), Gaps = 1/124 (0%)
Frame = -3
Query: 609 ENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGS 430
E PE+ G R + P + +EG TV+ NF C + R+ DHVM FL +LGTSG
Sbjct: 12 EETPEIDGTSERFEVPDPDIRQEG-NVTVYENFQSTCSRLGREDDHVMKFLQNDLGTSGH 70
Query: 429 LDGQQRLVVKGRFAPKNFEGILRRYVTEYVICLGCKSPDTILSKENRLFFLRCEKCGSGR 250
+D R+ + G F E + YV E+V+C C PDT L +E LRCE CG+
Sbjct: 71 IDESGRVRLTGEFDATRIEASIDEYVDEFVLCSECGLPDTQLEREQGALLLRCEACGARS 130
Query: 249 SVAQ 238
+ ++
Sbjct: 131 ATSE 134
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,471,325,924
Number of Sequences: 518415
Number of Extensions: 72471325924
Number of Successful Extensions: 505334272
Number of sequences better than 0.0: 0
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