BLASTX 7.6.2
Query= UN17959 /QuerySize=510
(509 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabi... 92 1e-018
sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kin... 71 4e-012
sp|Q9ESL4|MLTK_MOUSE Mitogen-activated protein kinase kinase kin... 70 6e-012
sp|Q8VDG6|M3KL4_MOUSE Mitogen-activated protein kinase kinase ki... 67 5e-011
sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase ki... 67 7e-011
sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase ki... 66 1e-010
sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase ki... 66 1e-010
sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kina... 66 1e-010
sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase D... 66 1e-010
sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase ki... 63 1e-009
sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase ki... 63 1e-009
sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase dr... 62 1e-009
sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kin... 62 1e-009
sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kin... 62 1e-009
sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase ki... 61 4e-009
sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase ki... 60 5e-009
sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dic... 58 3e-008
sp|Q6XHA7|ROCO9_DICDI Probable serine/threonine-protein kinase r... 57 5e-008
sp|Q3SWY2|ILK_BOVIN Integrin-linked protein kinase OS=Bos taurus... 56 9e-008
sp|Q13418|ILK_HUMAN Integrin-linked protein kinase OS=Homo sapie... 56 9e-008
>sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabidopsis thaliana
GN=HT1 PE=1 SV=1
Length = 390
Score = 92 bits (228), Expect = 1e-018
Identities = 43/71 (60%), Positives = 49/71 (69%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SFGIVLWEL T LLPFQ MT VQAAFAV + RP +PA C P L ++ RCW NP R
Sbjct: 271 SFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKR 330
Query: 328 PCFAEIVNLLE 296
P F+ IV +LE
Sbjct: 331 PDFSNIVAVLE 341
>sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo
sapiens GN=MLTK PE=1 SV=2
Length = 800
Score = 71 bits (172), Expect = 4e-012
Identities = 31/95 (32%), Positives = 57/95 (60%), Gaps = 7/95 (7%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
S+G+VLWE++T +PF+ + +Q A+ VV + R T+P+ C E++ +CW+A+ + R
Sbjct: 191 SYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKR 250
Query: 328 PCFAEIVNLLEAAETEVMTTVR-------KARFRC 245
P F +I+++LE+ + + KA +RC
Sbjct: 251 PSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRC 285
>sp|Q9ESL4|MLTK_MOUSE Mitogen-activated protein kinase kinase kinase MLT OS=Mus
musculus GN=Mltk PE=1 SV=1
Length = 802
Score = 70 bits (170), Expect = 6e-012
Identities = 27/76 (35%), Positives = 51/76 (67%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
S+G+VLWE++T +PF+ + +Q A+ VV + R T+P+ C E++ +CW+A+ + R
Sbjct: 191 SYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKR 250
Query: 328 PCFAEIVNLLEAAETE 281
P F +I+++LE+ +
Sbjct: 251 PSFKQIISILESMSND 266
>sp|Q8VDG6|M3KL4_MOUSE Mitogen-activated protein kinase kinase kinase OS=Mus
musculus GN=Mlk4 PE=2 SV=2
Length = 1002
Score = 67 bits (162), Expect = 5e-011
Identities = 28/86 (32%), Positives = 50/86 (58%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
S+G++LWEL+TG +P++ + + A+ V + +P+ C ++M CW+ +P +R
Sbjct: 313 SYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWEQDPHIR 372
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARF 251
P FA I+ L A E V+T + + F
Sbjct: 373 PSFALILQQLTAIEEAVLTNMPQESF 398
>sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase kinase OS=Homo
sapiens GN=MLK4 PE=1 SV=1
Length = 1036
Score = 67 bits (161), Expect = 7e-011
Identities = 29/86 (33%), Positives = 49/86 (56%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
S+G++LWEL+TG +P++ + + A+ V + +P+ C ++M CW +P +R
Sbjct: 329 SYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIR 388
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARF 251
P FA I+ L A E VMT + + F
Sbjct: 389 PSFALILEQLTAIEGAVMTEMPQESF 414
>sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo
sapiens GN=MAP3K11 PE=1 SV=1
Length = 847
Score = 66 bits (159), Expect = 1e-010
Identities = 29/86 (33%), Positives = 49/86 (56%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SFG++LWEL+TG +P++ + + A+ V + +P+ C ++M CW +P R
Sbjct: 307 SFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRR 366
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARF 251
P FA I+ LEA E +V+ + + F
Sbjct: 367 PDFASILQQLEALEAQVLREMPRDSF 392
>sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 OS=Mus
musculus GN=Map3k11 PE=1 SV=1
Length = 850
Score = 66 bits (159), Expect = 1e-010
Identities = 29/86 (33%), Positives = 49/86 (56%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SFG++LWEL+TG +P++ + + A+ V + +P+ C ++M CW +P R
Sbjct: 308 SFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRR 367
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARF 251
P FA I+ LEA E +V+ + + F
Sbjct: 368 PDFASILQQLEALEAQVLREMPRDSF 393
>sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase 11 OS=Rattus
norvegicus GN=Map3k11 PE=2 SV=1
Length = 850
Score = 66 bits (159), Expect = 1e-010
Identities = 29/86 (33%), Positives = 49/86 (56%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SFG++LWEL+TG +P++ + + A+ V + +P+ C ++M CW +P R
Sbjct: 308 SFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRR 367
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARF 251
P FA I+ LEA E +V+ + + F
Sbjct: 368 PDFASILQQLEALEAQVLREMPRDSF 393
>sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase DDB_G0268876
OS=Dictyostelium discoideum GN=DDB_G0268876 PE=3 SV=1
Length = 1385
Score = 66 bits (159), Expect = 1e-010
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SF VLWE I+ +P+++ +Q V+ RP +P CLP +++T CW +NP+ R
Sbjct: 936 SFAFVLWECISRQIPYKDFAQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDR 995
Query: 328 PCFAEIVNLLE 296
P F +I+ LE
Sbjct: 996 PSFQQIITYLE 1006
>sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 OS=Homo
sapiens GN=MAP3K10 PE=1 SV=3
Length = 954
Score = 63 bits (151), Expect = 1e-009
Identities = 26/78 (33%), Positives = 43/78 (55%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SFG++LWEL+TG +P++ + A+ A+ V + +P+ C ++ CWD +P R
Sbjct: 288 SFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347
Query: 328 PCFAEIVNLLEAAETEVM 275
P F I+ LE E +
Sbjct: 348 PDFGSILKRLEVIEQSAL 365
>sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kinase 10 OS=Mus
musculus GN=Map3k10 PE=2 SV=2
Length = 940
Score = 63 bits (151), Expect = 1e-009
Identities = 26/78 (33%), Positives = 43/78 (55%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SFG++LWEL+TG +P++ + A+ A+ V + +P+ C ++ CWD +P R
Sbjct: 288 SFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347
Query: 328 PCFAEIVNLLEAAETEVM 275
P F I+ LE E +
Sbjct: 348 PDFGSILKQLEVIEQSAL 365
>sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drkC
OS=Dictyostelium discoideum GN=drkC PE=3 SV=1
Length = 749
Score = 62 bits (150), Expect = 1e-009
Identities = 30/72 (41%), Positives = 39/72 (54%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SF IVLWE++T P+Q M Q +V +RP VP ++T CW +P+ R
Sbjct: 677 SFAIVLWEIVTREDPYQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQR 736
Query: 328 PCFAEIVNLLEA 293
P F EIV LEA
Sbjct: 737 PSFQEIVKRLEA 748
>sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 OS=Homo
sapiens GN=MAP3K9 PE=1 SV=3
Length = 1104
Score = 62 bits (150), Expect = 1e-009
Identities = 27/88 (30%), Positives = 46/88 (52%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
S+G++LWEL+TG +PF+ + + A+ V + +P+ C ++M CW+ +P R
Sbjct: 334 SYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSR 393
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARFRC 245
P F I++ L E + K F C
Sbjct: 394 PSFTNILDQLTTIEESGFFEMPKDSFHC 421
>sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kinase 9 OS=Mus
musculus GN=Map3k9 PE=2 SV=1
Length = 1077
Score = 62 bits (150), Expect = 1e-009
Identities = 27/88 (30%), Positives = 46/88 (52%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
S+G++LWEL+TG +PF+ + + A+ V + +P+ C ++M CW+ +P R
Sbjct: 327 SYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSR 386
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARFRC 245
P F I++ L E + K F C
Sbjct: 387 PSFTSILDQLTTIEESGFFEMPKDSFHC 414
>sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kinase 10
OS=Xenopus laevis GN=map3k10 PE=1 SV=1
Length = 1005
Score = 61 bits (146), Expect = 4e-009
Identities = 27/78 (34%), Positives = 43/78 (55%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SFG++LWEL+TG +P++ + A+ A+ V + +P+ C I+ CWD +P R
Sbjct: 308 SFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFVRILEACWDPDPHSR 367
Query: 328 PCFAEIVNLLEAAETEVM 275
P F+ I+ L E M
Sbjct: 368 PTFSCILEQLTTIEQSAM 385
>sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kinase
OS=Drosophila melanogaster GN=slpr PE=1 SV=1
Length = 1161
Score = 60 bits (145), Expect = 5e-009
Identities = 28/86 (32%), Positives = 42/86 (48%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
S+G++LWELITG P++ + A+ V + +P C G +M CW +P R
Sbjct: 330 SYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKR 389
Query: 328 PCFAEIVNLLEAAETEVMTTVRKARF 251
P F EI+ LE+ T + F
Sbjct: 390 PGFKEILKQLESIACSKFTLTPQESF 415
>sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dictyostelium
discoideum GN=pyk3 PE=1 SV=1
Length = 1338
Score = 58 bits (138), Expect = 3e-008
Identities = 24/74 (32%), Positives = 39/74 (52%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
++ VLWE +T LPF+ + A V +RP +P C ++ +++ RCW P R
Sbjct: 936 AYAFVLWEALTSHLPFRKFNDISVAAKVAYENLRPKIPTSCPLIIRKLINRCWAPLPSDR 995
Query: 328 PCFAEIVNLLEAAE 287
P F +I+ L + E
Sbjct: 996 PTFNDILKLFDHLE 1009
>sp|Q6XHA7|ROCO9_DICDI Probable serine/threonine-protein kinase roco9
OS=Dictyostelium discoideum GN=roco9 PE=3 SV=1
Length = 3365
Score = 57 bits (136), Expect = 5e-008
Identities = 26/79 (32%), Positives = 44/79 (55%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
++G++L+EL++ F N+T + ++ GVRP++P+ LP ++ CW +P R
Sbjct: 3193 AYGVILFELLSRTRFFSNITFMSEVEGLITEGVRPSLPSHNLPEYDSLLNICWAQDPTCR 3252
Query: 328 PCFAEIVNLLEAAETEVMT 272
P F EI LE E + T
Sbjct: 3253 PSFIEITKKLEEIELILKT 3271
>sp|Q3SWY2|ILK_BOVIN Integrin-linked protein kinase OS=Bos taurus GN=ILK PE=2
SV=1
Length = 452
Score = 56 bits (134), Expect = 9e-008
Identities = 26/71 (36%), Positives = 43/71 (60%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SF ++LWEL+T +PF +++ ++ V G+RPT+P P + ++M C + +P R
Sbjct: 377 SFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKR 436
Query: 328 PCFAEIVNLLE 296
P F IV +LE
Sbjct: 437 PKFDMIVPILE 447
>sp|Q13418|ILK_HUMAN Integrin-linked protein kinase OS=Homo sapiens GN=ILK PE=1
SV=2
Length = 452
Score = 56 bits (134), Expect = 9e-008
Identities = 26/71 (36%), Positives = 43/71 (60%)
Frame = -2
Query: 508 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPADCLPVLGEIMTRCWDANPEVR 329
SF ++LWEL+T +PF +++ ++ V G+RPT+P P + ++M C + +P R
Sbjct: 377 SFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKR 436
Query: 328 PCFAEIVNLLE 296
P F IV +LE
Sbjct: 437 PKFDMIVPILE 447
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,471,325,924
Number of Sequences: 518415
Number of Extensions: 72471325924
Number of Successful Extensions: 505334272
Number of sequences better than 0.0: 0
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