BLASTX 7.6.2
Query= UN18139 /QuerySize=1753
(1752 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q08DX7|SPNS1_BOVIN Protein spinster homolog 1 OS=Bos taurus G... 82 1e-014
sp|A2CER7|SPNS3_DANRE Protein spinster homolog 3 OS=Danio rerio ... 82 1e-014
sp|Q8R0G7|SPNS1_MOUSE Protein spinster homolog 1 OS=Mus musculus... 81 2e-014
sp|Q2YDU8|SPNS1_RAT Protein spinster homolog 1 OS=Rattus norvegi... 81 2e-014
sp|Q9H2V7|SPNS1_HUMAN Protein spinster homolog 1 OS=Homo sapiens... 80 3e-014
sp|Q9GQQ0|SPIN_DROME Protein spinster OS=Drosophila melanogaster... 79 7e-014
sp|Q9D232|SPNS3_MOUSE Protein spinster homolog 3 OS=Mus musculus... 79 9e-014
sp|Q8IVW8|SPNS2_HUMAN Protein spinster homolog 2 OS=Homo sapiens... 78 2e-013
sp|Q91VM4|SPNS2_MOUSE Protein spinster homolog 2 OS=Mus musculus... 78 2e-013
sp|B0JZE1|SPNS2_XENTR Protein spinster homolog 2 OS=Xenopus trop... 78 2e-013
sp|A8WGF7|SPNS1_XENTR Protein spinster homolog 1 OS=Xenopus trop... 75 2e-012
sp|Q5XGK0|SPNS1_XENLA Protein spinster homolog 1 OS=Xenopus laev... 74 4e-012
sp|Q6ZMD2|SPNS3_HUMAN Protein spinster homolog 3 OS=Homo sapiens... 68 2e-010
sp|Q7ZU13|SPNS1_DANRE Protein spinster homolog 1 OS=Danio rerio ... 66 6e-010
sp|P38358|VBA2_YEAST Vacuolar basic amino acid transporter 2 OS=... 63 5e-009
sp|Q00357|TOXA_COCCA Putative HC-toxin efflux carrier TOXA OS=Co... 56 8e-007
>sp|Q08DX7|SPNS1_BOVIN Protein spinster homolog 1 OS=Bos taurus GN=SPNS1 PE=2
SV=1
Length = 528
Score = 82 bits (200), Expect = 1e-014
Identities = 48/150 (32%), Positives = 73/150 (48%), Gaps = 3/150 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ +V +P+F L R+ L+ G+ W+L +G F FW++ + R VGVG
Sbjct: 104 FISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPRERFWLLLLTRGLVGVG 163
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D A +++ L +FY IP G LGY+ G V + G W WA +
Sbjct: 164 EASYSTIAPTLIADLFVADQRSRMLSVFYFAIPVGSGLGYIAGSKVKDVAGDWHWALRVT 223
Query: 719 AIAMAFFVVLSFCIKPPQLKGFAAKESKKP 808
VVL F + +G + S P
Sbjct: 224 PGLGVLAVVLLFLVVQEPPRGAVERHSDSP 253
>sp|A2CER7|SPNS3_DANRE Protein spinster homolog 3 OS=Danio rerio GN=spns3 PE=2
SV=1
Length = 498
Score = 82 bits (200), Expect = 1e-014
Identities = 44/138 (31%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ + +P+F L R+ ++ VGL +W + +G F +FW++ R VG G
Sbjct: 93 FICSFMFLAPVFGYLGDRYDRKLIMIVGLVMWIVTTLGSSFVRKSHFWVLVATRALVGTG 152
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D +++ L + FY+ IP G LGY+ G V + G WRWA +
Sbjct: 153 EASYSTIAPTIIGDLFAGSKRTLMISFFYIFIPVGSGLGYIIGATVADATGDWRWALRVS 212
Query: 719 -AIAMAFFVVLSFCIKPP 769
A+ ++L F I P
Sbjct: 213 PALGGLGLLLLVFLIPNP 230
>sp|Q8R0G7|SPNS1_MOUSE Protein spinster homolog 1 OS=Mus musculus GN=Spns1 PE=2
SV=1
Length = 528
Score = 81 bits (198), Expect = 2e-014
Identities = 47/150 (31%), Positives = 74/150 (49%), Gaps = 3/150 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ +V +P+F L R+ L+ G+ W+L +G F +FW++ + R VGVG
Sbjct: 104 FISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPREHFWLLLLTRGLVGVG 163
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D A +++ L +FY IP G LGY+ G V + G W WA +
Sbjct: 164 EASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDVAGDWHWALRVT 223
Query: 719 AIAMAFFVVLSFCIKPPQLKGFAAKESKKP 808
V+L F + +G + S P
Sbjct: 224 PGLGVLAVLLLFLVVQEPPRGAVERHSGSP 253
>sp|Q2YDU8|SPNS1_RAT Protein spinster homolog 1 OS=Rattus norvegicus GN=Spns1
PE=2 SV=2
Length = 528
Score = 81 bits (198), Expect = 2e-014
Identities = 47/150 (31%), Positives = 74/150 (49%), Gaps = 3/150 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ +V +P+F L R+ L+ G+ W+L +G F +FW++ + R VGVG
Sbjct: 104 FISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPREHFWLLLLTRGLVGVG 163
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D A +++ L +FY IP G LGY+ G V + G W WA +
Sbjct: 164 EASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDLAGDWHWALRVT 223
Query: 719 AIAMAFFVVLSFCIKPPQLKGFAAKESKKP 808
V+L F + +G + S P
Sbjct: 224 PGLGVLAVLLLFLVVQEPPRGAVERHSGSP 253
>sp|Q9H2V7|SPNS1_HUMAN Protein spinster homolog 1 OS=Homo sapiens GN=SPNS1 PE=1
SV=1
Length = 528
Score = 80 bits (197), Expect = 3e-014
Identities = 47/150 (31%), Positives = 74/150 (49%), Gaps = 3/150 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ +V +P+F L R+ L+ G+ W+L +G F +FW++ + R VGVG
Sbjct: 104 FISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPGEHFWLLLLTRGLVGVG 163
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D A +++ L +FY IP G LGY+ G V + G W WA +
Sbjct: 164 EASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDMAGDWHWALRVT 223
Query: 719 AIAMAFFVVLSFCIKPPQLKGFAAKESKKP 808
V+L F + +G + S P
Sbjct: 224 PGLGVVAVLLLFLVVREPPRGAVERHSDLP 253
>sp|Q9GQQ0|SPIN_DROME Protein spinster OS=Drosophila melanogaster GN=spin PE=1
SV=1
Length = 605
Score = 79 bits (194), Expect = 7e-014
Identities = 46/136 (33%), Positives = 66/136 (48%), Gaps = 3/136 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGFSYNFWMIAVFRMFVGVGEA 547
F++ +V +PIF L R++ ++ VG+ +W+ + F F FR VG+GEA
Sbjct: 159 FVISYMVCAPIFGYLGDRYSRPWIMAVGVGLWSTTTLLGSFMKQFGWFIAFRALVGIGEA 218
Query: 548 SFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG--WRWAFYIEA 721
S+ ++A I D ++ L LFY IP G LGY+ G HL WRWA +
Sbjct: 219 SYSTIAPTIISDLFVHDMRSKMLALFYFAIPVGSGLGYIVGSKTA-HLANDWRWALRVTP 277
Query: 722 IAMAFFVVLSFCIKPP 769
I V L IK P
Sbjct: 278 ILGIVAVFLILLIKDP 293
>sp|Q9D232|SPNS3_MOUSE Protein spinster homolog 3 OS=Mus musculus GN=Spns3 PE=2
SV=1
Length = 514
Score = 79 bits (193), Expect = 9e-014
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 3/148 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF-SYNF-WMIAVFRMFVGVG 541
F+ LLV++P+F L R+ ++ G+ +W+ A + F SY + W+ + R FVG G
Sbjct: 94 FISCLLVSAPVFGYLGDRYNRKAILSFGILLWSGAGLSSSFISYQYSWLFFLSRGFVGTG 153
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
AS+ ++A + D ++ L +FY+ IP G LGYV G V G WRWA +
Sbjct: 154 AASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRLM 213
Query: 719 AIAMAFFVVLSFCIKPPQLKGFAAKESK 802
A + L + P +G A K+ +
Sbjct: 214 PCLDAMALALLILLVPDVPRGAAEKQGE 241
>sp|Q8IVW8|SPNS2_HUMAN Protein spinster homolog 2 OS=Homo sapiens GN=SPNS2 PE=1
SV=2
Length = 549
Score = 78 bits (191), Expect = 2e-013
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ +VA+PIF L RF ++ G+ W+ F FW++ + R VG+G
Sbjct: 147 FICSFMVAAPIFGYLGDRFNRKVILSCGIFFWSAVTFSSSFIPQQYFWLLVLSRGLVGIG 206
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D + L L +FY IP G LGY+ G V G W WA +
Sbjct: 207 EASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDWHWALRVS 266
Query: 719 AIAMAFFVVLSFCIKPPQLKGFA 787
+ L + P +G A
Sbjct: 267 PVLGMITGTLILILVPATKRGHA 289
>sp|Q91VM4|SPNS2_MOUSE Protein spinster homolog 2 OS=Mus musculus GN=Spns2 PE=2
SV=2
Length = 549
Score = 78 bits (191), Expect = 2e-013
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ +VA+PIF L RF ++ G+ W+ F FW++ + R VG+G
Sbjct: 147 FICSFMVAAPIFGYLGDRFNRKVILSCGIFFWSAVTFSSSFIPQQYFWLLVLSRGLVGIG 206
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D + L L +FY IP G LGY+ G V G W WA +
Sbjct: 207 EASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDWHWALRVS 266
Query: 719 AIAMAFFVVLSFCIKPPQLKGFA 787
+ L + P +G A
Sbjct: 267 PVLGMITGTLILILVPATKRGHA 289
>sp|B0JZE1|SPNS2_XENTR Protein spinster homolog 2 OS=Xenopus tropicalis GN=spns2
PE=2 SV=1
Length = 513
Score = 78 bits (191), Expect = 2e-013
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ +VA+PIF L RF ++ G+ W+ F FW++ + R VG+G
Sbjct: 108 FICSFMVAAPIFGYLGDRFNRKVILSSGIFFWSAITFSSSFIPKKYFWLLVLSRGLVGIG 167
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYIE 718
EAS+ ++A I D + L L +FY IP G LGY+ G V G WRWA +
Sbjct: 168 EASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQVAGDWRWALRVS 227
Query: 719 AIAMAFFVVLSFCIKPPQLKGFA 787
+ L P +G A
Sbjct: 228 PVLGVITGTLLLIFVPTAKRGHA 250
>sp|A8WGF7|SPNS1_XENTR Protein spinster homolog 1 OS=Xenopus tropicalis GN=spns1
PE=2 SV=2
Length = 526
Score = 75 bits (182), Expect = 2e-012
Identities = 44/151 (29%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ + +P+F L R+ ++ +G++ W+L + F FW+ + R VGVG
Sbjct: 104 FICSYMFLAPVFGYLGDRYNRKLIMCIGISFWSLVTLLSSFVSKQYFWLFLLTRGLVGVG 163
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYI- 715
EAS+ ++A I D A +++ L FY P G LGY+ G V + G W WA +
Sbjct: 164 EASYSTIAPTIIADLFLADQRSRMLSFFYFATPVGCGLGYIAGSKVTSTAGDWHWALRVT 223
Query: 716 EAIAMAFFVVLSFCIKPPQLKGFAAKESKKP 808
+ + ++L F K P +G ++S +P
Sbjct: 224 PGLGLVAVLLLIFVAKEPP-RGALERKSDRP 253
>sp|Q5XGK0|SPNS1_XENLA Protein spinster homolog 1 OS=Xenopus laevis GN=spns1
PE=2 SV=1
Length = 526
Score = 74 bits (179), Expect = 4e-012
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGFSYN--FWMIAVFRMFVGVG 541
F+ + +P+F L R+ ++ VG++ W+L + F N FW+ + R VGVG
Sbjct: 104 FICSYMFLAPVFGYLGDRYNRKLIMCVGISFWSLVTLLSSFVSNQYFWLFLITRGLVGVG 163
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWAFYI- 715
EAS+ ++A I D A ++ L FY P G LGY+ G + + G W WA +
Sbjct: 164 EASYSTIAPTIIADLFLADQRTRMLSFFYFATPVGCGLGYIVGSEMTSAAGDWHWALRVT 223
Query: 716 EAIAMAFFVVLSFCIKPPQLKGFAAKESKKP 808
+ + ++L F + P +G +++ +P
Sbjct: 224 PGLGLLAVLLLIFVAEEPP-RGALERKTDRP 253
>sp|Q6ZMD2|SPNS3_HUMAN Protein spinster homolog 3 OS=Homo sapiens GN=SPNS3 PE=2
SV=2
Length = 512
Score = 68 bits (165), Expect = 2e-010
Identities = 44/152 (28%), Positives = 72/152 (47%), Gaps = 11/152 (7%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGFSYNF------WMIAVFRMF 529
F+ LL+++P+F L R + + G+ +W+ G G S +F W+ + R
Sbjct: 90 FVSCLLLSAPVFGYLGDRHSRKATMSFGILLWS----GAGLSSSFISPRYSWLFFLSRGI 145
Query: 530 VGVGEASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLG-WRWA 706
VG G AS+ ++A + D ++ L +FY+ IP G LGYV G V G WRWA
Sbjct: 146 VGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLGSAVTMLTGNWRWA 205
Query: 707 FYIEAIAMAFFVVLSFCIKPPQLKGFAAKESK 802
+ A ++L + P +G A + +
Sbjct: 206 LRVMPCLEAVALILLILLVPDPPRGAAETQGE 237
>sp|Q7ZU13|SPNS1_DANRE Protein spinster homolog 1 OS=Danio rerio GN=spns1 PE=2
SV=1
Length = 506
Score = 66 bits (160), Expect = 6e-010
Identities = 35/119 (29%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Frame = +2
Query: 368 FMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGF--SYNFWMIAVFRMFVGVG 541
F+ + +P+F L R+ ++ VG+ W++ + F +FW + + R VGVG
Sbjct: 93 FICSYMFLAPLFGYLGDRYNRKLIMCVGIFFWSVVTLASSFIGKDHFWALLLTRGLVGVG 152
Query: 542 EASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGN-HLGWRWAFYI 715
EAS+ ++A I D ++ L +FY IP G +GY+ G V W WA +
Sbjct: 153 EASYSTIAPTIIADLFVKEKRTNMLSIFYFAIPVGSGMGYIVGSKVDTVAKDWHWALRV 211
>sp|P38358|VBA2_YEAST Vacuolar basic amino acid transporter 2 OS=Saccharomyces
cerevisiae GN=VBA2 PE=1 SV=1
Length = 474
Score = 63 bits (152), Expect = 5e-009
Identities = 28/118 (23%), Positives = 56/118 (47%)
Frame = +2
Query: 365 AFMVGLLVASPIFAALSKRFTPFKLIGVGLTVWTLAAVGCGFSYNFWMIAVFRMFVGVGE 544
A+++ P++ + S + +T+ + CGFS N +M++ R G+G
Sbjct: 10 AYLITSTSFQPLYGSFSDALGRRNCLFFANGAFTIGCLACGFSKNIYMLSFMRALTGIGG 69
Query: 545 ASFISLAAPYIDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLGWRWAFYIE 718
I+L+ D P++++ ++ + + G G FGG + + +GWRW F I+
Sbjct: 70 GGLITLSTIVNSDVIPSSKRGIFQAFQNLLLGFGAICGASFGGTIASSIGWRWCFLIQ 127
>sp|Q00357|TOXA_COCCA Putative HC-toxin efflux carrier TOXA OS=Cochliobolus
carbonum GN=TOXA PE=3 SV=1
Length = 548
Score = 56 bits (133), Expect = 8e-007
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 1/127 (0%)
Frame = +2
Query: 395 PIFAALSKRFTPFKLIGVGLTVWTLAAVGCGFSYNFWMIAVFRMFVGVGEASFISLAAPY 574
P+F L F+P L L V L ++ C + N V R G+G +S A
Sbjct: 102 PLFGKLYNEFSPKWLFITCLIVLQLGSLVCALARNSPTFIVGRAVAGIGAGGILSGALNI 161
Query: 575 IDDSAPAARKNLWLGLFYMCIPAGVALGYVFGGYVGNHLGWRWAFYIE-AIAMAFFVVLS 751
+ P + + G+ + +G + GG + +++GWRW F+I I A +L
Sbjct: 162 VALIVPLHHRAAFTGMIGALECVALIIGPIIGGAIADNIGWRWCFWINLPIGAAVCAILL 221
Query: 752 FCIKPPQ 772
F PP+
Sbjct: 222 FFFHPPR 228
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,436,365,428
Number of Sequences: 518415
Number of Extensions: 75436365428
Number of Successful Extensions: 513409628
Number of sequences better than 0.0: 0
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