BLASTX 7.6.2
Query= UN18219 /QuerySize=1518
(1517 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS... 693 9e-199
sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 O... 634 6e-181
sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS... 535 5e-151
sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Or... 238 1e-061
sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arab... 237 2e-061
sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferas... 223 4e-057
sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia l... 220 3e-056
sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyc... 218 1e-055
sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida gl... 215 9e-055
sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromy... 213 3e-054
sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida al... 213 5e-054
sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosacc... 212 8e-054
sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora... 211 1e-053
sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomy... 211 1e-053
sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocyst... 210 4e-053
sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporth... 208 1e-052
sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora... 202 8e-051
sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gos... 198 2e-049
sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplas... 72 7e-012
sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltrans... 72 1e-011
>sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS=Arabidopsis
thaliana GN=SMT2 PE=1 SV=2
Length = 361
Score = 693 bits (1788), Expect = 9e-199
Identities = 333/356 (93%), Positives = 347/356 (97%)
Frame = +2
Query: 56 MDSVALFFTGALVAGGIYWFLCVLGPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFRR 235
MDS+ LFFTGALVA GIYWFLCVLGPAERKGKRA+DLSGGSISAEKVQDNYKQYWSFFRR
Sbjct: 1 MDSLTLFFTGALVAVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQDNYKQYWSFFRR 60
Query: 236 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 415
PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSI GKSH+DATRLHEEMAVDLIQ
Sbjct: 61 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSHKDATRLHEEMAVDLIQ 120
Query: 416 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 595
VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQV RAR HN+KAGLDALCEVVCG
Sbjct: 121 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVNRARLHNKKAGLDALCEVVCG 180
Query: 596 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENE 775
NFLQMPFDDN+FDGAYSIEATCHAPKLEEVYAEIYRVLKPGS+YVSYEWVTT+KF AE++
Sbjct: 181 NFLQMPFDDNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEKFKAEDD 240
Query: 776 EHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 955
EHVEVIQGIERGDALPGLRAY DIAETAKKVGFE+VKEKDLA+PPAEPWWTRLKMGRLAY
Sbjct: 241 EHVEVIQGIERGDALPGLRAYVDIAETAKKVGFEIVKEKDLASPPAEPWWTRLKMGRLAY 300
Query: 956 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKPIS 1123
WRNHIVVQ+LSAVGVAPKGTVDVHEMLFKTAD+L+RGGET IFSPMHMILCRKP S
Sbjct: 301 WRNHIVVQILSAVGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPES 356
>sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 OS=Arabidopsis
thaliana GN=SMT3 PE=2 SV=1
Length = 359
Score = 634 bits (1634), Expect = 6e-181
Identities = 293/354 (82%), Positives = 332/354 (93%)
Frame = +2
Query: 56 MDSVALFFTGALVAGGIYWFLCVLGPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFRR 235
MDSVAL+ T L+AG +YWF+CVLGPAERKGKRA DLSGGSISAEKV+DNY QYWSFFR+
Sbjct: 1 MDSVALYCTAGLIAGAVYWFICVLGPAERKGKRASDLSGGSISAEKVKDNYNQYWSFFRK 60
Query: 236 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 415
PKEIE+AEKVPDFVDTFYNLVTDIYEWGWGQSFHFSP + GKS +DATR+HEEMAVDLI+
Sbjct: 61 PKEIESAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPHVPGKSDKDATRIHEEMAVDLIK 120
Query: 416 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 595
VKPGQKILD GCGVGGPMRAIA+HS+A V GITINEYQV+RA+ HN+KAGLD+LC VVCG
Sbjct: 121 VKPGQKILDAGCGVGGPMRAIAAHSKAQVTGITINEYQVQRAKLHNKKAGLDSLCNVVCG 180
Query: 596 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENE 775
NFL+MPFD+NTFDGAYSIEATCHAPKLEEVY+EI+RV+KPGSL+VSYEWVTT+K+ ++E
Sbjct: 181 NFLKMPFDENTFDGAYSIEATCHAPKLEEVYSEIFRVMKPGSLFVSYEWVTTEKYRDDDE 240
Query: 776 EHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 955
EH +VIQGIERGDALPGLR+Y+DIA TAKKVGFEVVKEKDLA PP++PWW RLKMGR+AY
Sbjct: 241 EHKDVIQGIERGDALPGLRSYADIAVTAKKVGFEVVKEKDLAKPPSKPWWNRLKMGRIAY 300
Query: 956 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKP 1117
WRNH+VV +LSA+GVAPKGTVDVH+MLFKTAD+L+RGGET IFSPMHMILCRKP
Sbjct: 301 WRNHVVVVILSAIGVAPKGTVDVHKMLFKTADYLTRGGETGIFSPMHMILCRKP 354
>sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS=Oryza sativa
subsp. japonica GN=Smt2-1 PE=2 SV=2
Length = 363
Score = 535 bits (1376), Expect = 5e-151
Identities = 253/360 (70%), Positives = 298/360 (82%), Gaps = 5/360 (1%)
Frame = +2
Query: 56 MDSVALFFTGALVAGG-IYWFLCVLGPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFR 232
M++ + +T A V +YWF+ V+G AE KGKRA+DL GSI+ +KV+D Y QYWSFFR
Sbjct: 1 MEAATMAWTAAGVGMALVYWFVWVMGAAEVKGKRAVDLKMGSITNDKVKDKYTQYWSFFR 60
Query: 233 RPKEIET----AEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMA 400
RPKE T AEKVP FVDTFYNLVTDIYEWGWGQSFHFSPS+ G+SHR+ATR+HEE
Sbjct: 61 RPKETATTEASAEKVPAFVDTFYNLVTDIYEWGWGQSFHFSPSLPGRSHREATRVHEERV 120
Query: 401 VDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALC 580
DL+Q KPG ++LDVGCGVGGPMRAIA+HS +NVVGITINEYQV RAR HNRKAGLD+ C
Sbjct: 121 ADLLQAKPGHRLLDVGCGVGGPMRAIAAHSGSNVVGITINEYQVNRARAHNRKAGLDSRC 180
Query: 581 EVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKF 760
EVVCGNFL MPF D +FDGAYSIEATCHAP+L++VY E++RVLKPG LYVSYEWVTT +
Sbjct: 181 EVVCGNFLSMPFSDASFDGAYSIEATCHAPRLQDVYGEVFRVLKPGGLYVSYEWVTTSLY 240
Query: 761 NAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDLAAPPAEPWWTRLKM 940
A+N EHVE I GIERGDALPGLR +IA AK+VGFEV+KE DLA PPA PWWTRLKM
Sbjct: 241 RADNPEHVEAIHGIERGDALPGLRRQDEIASIAKEVGFEVLKELDLALPPALPWWTRLKM 300
Query: 941 GRLAYWRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKPI 1120
GR+AYWRN +VV+VL+ + +APKG +VHEML++TA L+RGGET IF+PMHM+L RKP+
Sbjct: 301 GRIAYWRNSLVVRVLTMLRIAPKGVCEVHEMLYETAQHLTRGGETGIFTPMHMVLLRKPV 360
>sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Oryza sativa
subsp. japonica GN=Smt1-1 PE=2 SV=1
Length = 344
Score = 238 bits (605), Expect = 1e-061
Identities = 118/272 (43%), Positives = 164/272 (60%), Gaps = 7/272 (2%)
Frame = +2
Query: 155 ALDLS---GGSISAEKVQ---DNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 316
A+DL+ GG I+ ++V+ D Y++Y ++ KE D V+ +Y+L T YE+
Sbjct: 6 AMDLASGLGGKITKDEVKSAVDEYEKYHGYY-GGKEEARKSNYTDMVNKYYDLATSFYEY 64
Query: 317 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 496
GWG+SFHF+ G+S R++ + HE + VKPG K+LDVGCG+GGP+R IA S A
Sbjct: 65 GWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGMKVLDVGCGIGGPLREIAKFSLA 124
Query: 497 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 676
+V G+ NEYQ+ R ++ NR AG+ C+ V +F++MPF DNTFD Y+IEATCHAP
Sbjct: 125 SVTGLNNNEYQITRGKELNRVAGVSGTCDFVKADFMKMPFSDNTFDAVYAIEATCHAPDP 184
Query: 677 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAET 856
Y EIYRVLKPG + YEW TD + N H + IE G+ LP +R+ +
Sbjct: 185 VGCYKEIYRVLKPGQCFAVYEWCITDHYEPNNATHKRIKDEIELGNGLPDIRSTQQCLQA 244
Query: 857 AKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLA 952
AK GFEV+ +KDLA PW+ L R +
Sbjct: 245 AKDAGFEVIWDKDLAEDSPVPWYLPLDPSRFS 276
>sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arabidopsis
thaliana GN=SMT1 PE=2 SV=1
Length = 336
Score = 237 bits (603), Expect = 2e-061
Identities = 116/258 (44%), Positives = 158/258 (61%), Gaps = 4/258 (1%)
Frame = +2
Query: 170 GGSISAEKV---QDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHF 340
GG I V + Y+QY F E E D V+ +Y+L T YE+GWG+SFHF
Sbjct: 8 GGKIDKSDVLTAVEKYEQY-HVFHGGNEEERKANYTDMVNKYYDLATSFYEYGWGESFHF 66
Query: 341 SPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITIN 520
+ +G+S R++ + HE + ++PGQK+LDVGCG+GGP+R IA S + V G+ N
Sbjct: 67 AQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVVTGLNNN 126
Query: 521 EYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIY 700
EYQ+ R ++ NR AG+D C V +F++MPF +N+FD Y+IEATCHAP Y EIY
Sbjct: 127 EYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYGCYKEIY 186
Query: 701 RVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEV 880
RVLKPG + +YEW TD F+ +N EH ++ IE GD LP +R + E K+ GFEV
Sbjct: 187 RVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALKQAGFEV 246
Query: 881 VKEKDLAAPPAEPWWTRL 934
+ EKDLA PW+ L
Sbjct: 247 IWEKDLAKDSPVPWYLPL 264
>sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferase 1
OS=Dictyostelium discoideum GN=smt1 PE=1 SV=1
Length = 354
Score = 223 bits (566), Expect = 4e-057
Identities = 111/255 (43%), Positives = 154/255 (60%), Gaps = 3/255 (1%)
Frame = +2
Query: 188 EKVQDNYKQYWSFFR--RPKEIETAE-KVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRG 358
+KV D Y F+ K I+ + V+TFY+L TD YE+GWGQSFHF+ +
Sbjct: 30 DKVDDTLNGYKELFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKY 89
Query: 359 KSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 538
+S + HE + + PG K++D+GCGVGGPMR IA S ANVVG+ NEYQ++R
Sbjct: 90 ESFEASIARHEMYMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQR 149
Query: 539 ARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPG 718
+ N AGL LC + +F+ +P +DNT+D AY IEATCHAP L +Y E++R++KPG
Sbjct: 150 GKRLNESAGLSHLCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPG 209
Query: 719 SLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDL 898
L+ YEW+ T+KFN E+ V + + IE G+ LP L ++I AK GFEV+ D+
Sbjct: 210 GLFGGYEWIMTNKFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDV 269
Query: 899 AAPPAEPWWTRLKMG 943
A PW+ L G
Sbjct: 270 AETSELPWYLPLSSG 284
>sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia lipolytica
GN=ERG6 PE=3 SV=1
Length = 381
Score = 220 bits (559), Expect = 3e-056
Identities = 104/215 (48%), Positives = 143/215 (66%), Gaps = 1/215 (0%)
Frame = +2
Query: 284 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 463
+YNLVTD YE+GWG SFHFS +G++ R AT HE + ++PG K+LDVGCGVGG
Sbjct: 82 YYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHYLAYKMGIQPGMKVLDVGCGVGG 141
Query: 464 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 643
P R IA + AN+VG+ N+YQV+R ++ G V G+F+QM F DN+FD Y
Sbjct: 142 PAREIARFTGANIVGLNNNDYQVERGTHYSEVQGFGDQVTYVKGDFMQMDFPDNSFDAVY 201
Query: 644 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALP 823
+IEAT HAP LE VY+EI+RVLKPG ++ YEWV TD+++ N EH ++ GIE+GD +P
Sbjct: 202 AIEATVHAPVLEGVYSEIFRVLKPGGVFGVYEWVMTDEYDESNPEHRDICYGIEKGDGIP 261
Query: 824 GLRAYSDIAETAKKVGFEVVKEKDLAAPPAE-PWW 925
+ + + VGF++ ++DLAA AE PW+
Sbjct: 262 KMYKREVAVKALENVGFDIEYQEDLAADDAEVPWY 296
>sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyces hansenii
GN=ERG6 PE=3 SV=1
Length = 377
Score = 218 bits (554), Expect = 1e-055
Identities = 113/265 (42%), Positives = 158/265 (59%), Gaps = 3/265 (1%)
Frame = +2
Query: 137 ERKGKRALDLSGGSISAEKVQDNYKQYW-SFFRRPKEIETAEKVPDFVDTFYNLVTDIYE 313
++ G +AL +S ++E D Y ++W + E + + +YNLVTD YE
Sbjct: 28 KQTGLKAL-MSKARDASEVANDGYFKHWDGGVTKEDEDKRLSDYSNLTAHYYNLVTDFYE 86
Query: 314 WGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSR 493
+GWG SFHFS G++ R AT HE +Q+ K+LDVGCGVGGP R I +
Sbjct: 87 YGWGSSFHFSRYYTGEAFRQATARHEHFLAHKMQINENMKVLDVGCGVGGPAREICRFTD 146
Query: 494 ANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPK 673
++VG+ N+YQ++RA + RK LD V G+F+QM F+ +FD Y+IEAT HAP
Sbjct: 147 CSIVGLNNNDYQIERANHYARKYKLDDKLSFVKGDFMQMDFEAESFDAVYAIEATVHAPV 206
Query: 674 LEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAE 853
LE VY+EIY+VLKPG ++ YEWV TDK++ ENEEH ++ GIE GD +P + +
Sbjct: 207 LEGVYSEIYKVLKPGGVFGVYEWVMTDKYDDENEEHRKIAYGIEVGDGIPKMYKREVAEK 266
Query: 854 TAKKVGFEVVKEKDLAAPPAE-PWW 925
K VGFE+ E DLA + PW+
Sbjct: 267 ALKSVGFEIEYEADLADKEDDIPWY 291
>sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida glabrata GN=ERG6
PE=3 SV=1
Length = 372
Score = 215 bits (546), Expect = 9e-055
Identities = 112/269 (41%), Positives = 158/269 (58%), Gaps = 5/269 (1%)
Frame = +2
Query: 128 GPAERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIE--TAEKVPDFVDTFYNLVT 301
G R G AL LS + + Y ++W + KE E E + ++YN+VT
Sbjct: 21 GAESRTGLTAL-LSKNRNAQREAVSKYLRHWD-GKTDKEAEDRRLEDYNEATHSYYNVVT 78
Query: 302 DIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIA 481
D YE+GWG SFHFS +G++ + A HE+ + +K G +LDVGCGVGGP R IA
Sbjct: 79 DFYEYGWGSSFHFSRFYKGENFQAAMARHEQYLAYMAGIKKGDLVLDVGCGVGGPARTIA 138
Query: 482 SHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATC 661
+ N++G+ N+YQ+++A+ + +K L + V G+F+ M F+ N+FD Y+IEATC
Sbjct: 139 RFTGCNIIGLNNNDYQIQKAKYYAKKYNLQDHMDFVKGDFMNMEFEPNSFDKVYAIEATC 198
Query: 662 HAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYS 841
HAPKLE VY EIY+VLKPG + YEWV T+ ++ NEEH ++ IE GD +P +
Sbjct: 199 HAPKLEGVYGEIYKVLKPGGTFAVYEWVMTENYDENNEEHRKIAYEIELGDGIPKMFTVD 258
Query: 842 DIAETAKKVGFEVVKEKDLAAPPAE-PWW 925
+ K VGFEV KDLA E PW+
Sbjct: 259 VAKQALKNVGFEVEVSKDLADEDDEIPWY 287
>sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromyces lactis
GN=ERG6 PE=3 SV=1
Length = 371
Score = 213 bits (541), Expect = 3e-054
Identities = 108/266 (40%), Positives = 151/266 (56%), Gaps = 1/266 (0%)
Frame = +2
Query: 140 RKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWG 319
+ G AL S E V K + E E + ++YN+VTD YE+G
Sbjct: 25 KSGFSALVSKNKSAQTEAVAKYLKHWDGKTDADAERRRLEDYNESTHSYYNVVTDFYEYG 84
Query: 320 WGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRAN 499
WG SFHFS +G+S + HE +K ILDVGCGVGGP R I+ + N
Sbjct: 85 WGSSFHFSRFFKGESFSASVARHEHYLAYKAGIKENDLILDVGCGVGGPARTISRFTGCN 144
Query: 500 VVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLE 679
++G+ N+YQ+++A + ++ LD+ V G+F++M FD+NTFD Y+IEATCHAP E
Sbjct: 145 IIGLNNNDYQIQKANYYAKRDHLDSKLSFVKGDFMKMEFDENTFDSVYAIEATCHAPTFE 204
Query: 680 EVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETA 859
VY EIY+VLKPG + YEWV TDK++ N EH ++ IE GD +P + + +
Sbjct: 205 GVYGEIYKVLKPGGTFAVYEWVMTDKYDETNPEHRKIAYEIELGDGIPKMYSVDAARDAL 264
Query: 860 KKVGFEVVKEKDLAAPPAE-PWWTRL 934
KVGFE+++E DLA E PW+ L
Sbjct: 265 SKVGFEILEENDLADNDDEIPWYAPL 290
>sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida albicans GN=ERG6
PE=3 SV=1
Length = 376
Score = 213 bits (540), Expect = 5e-054
Identities = 107/264 (40%), Positives = 152/264 (57%), Gaps = 1/264 (0%)
Frame = +2
Query: 137 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 316
++ G AL ++ + +K + + E + +YNLVTD YE+
Sbjct: 27 KKTGLSALIAKSKDAASVAAEGYFKHWDGGISKDDEEKRLNDYSQLTHHYYNLVTDFYEY 86
Query: 317 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 496
GWG SFHFS +G++ R AT HE + + K+LDVGCGVGGP R I +
Sbjct: 87 GWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNLNENMKVLDVGCGVGGPGREITRFTDC 146
Query: 497 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 676
+VG+ N+YQ++RA + +K LD V G+F+QM F+ +FD Y+IEAT HAP L
Sbjct: 147 EIVGLNNNDYQIERANHYAKKYHLDHKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVL 206
Query: 677 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAET 856
E VY+EIY+VLKPG ++ YEWV TDK++ NEEH ++ GIE GD +P + + +
Sbjct: 207 EGVYSEIYKVLKPGGIFGVYEWVMTDKYDETNEEHRKIAYGIEVGDGIPKMYSRKVAEQA 266
Query: 857 AKKVGFEVVKEKDLAAPPAE-PWW 925
K VGFE+ +KDLA E PW+
Sbjct: 267 LKNVGFEIEYQKDLADVDDEIPWY 290
>sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosaccharomyces pombe
GN=SPBC16E9.05 PE=2 SV=1
Length = 378
Score = 212 bits (538), Expect = 8e-054
Identities = 112/273 (41%), Positives = 159/273 (58%), Gaps = 13/273 (4%)
Frame = +2
Query: 146 GKRALDLSGGSISAEKVQD----NYKQYWSFFRRPKEIETAEK-------VPDFVDTFYN 292
GK A +G + A K D ++Y+ F+ R E E+ E V+++Y+
Sbjct: 21 GKAAEKKTGLAAIASKDVDEQSRKLQEYFEFWDRNHENESEEDRARRIDGYKSVVNSYYD 80
Query: 293 LVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMR 472
L TD+YE+GW QSFHFS +G++ + HE + +KPG ++LDVGCGVGGP R
Sbjct: 81 LATDLYEYGWSQSFHFSRFYKGEAFAQSIARHEHYLAYRMGIKPGSRVLDVGCGVGGPAR 140
Query: 473 AIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIE 652
I + N+VG+ N+YQ+ R ++ K LD V G+F+ MPF+DNTFD Y+IE
Sbjct: 141 EITEFTGCNLVGLNNNDYQISRCNNYAVKRNLDKKQVFVKGDFMHMPFEDNTFDYVYAIE 200
Query: 653 ATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLR 832
AT HAP LE VY EI+RVLKPG ++ YEWV +D +++ +H E+ IE GD +P +
Sbjct: 201 ATVHAPSLEGVYGEIFRVLKPGGVFGVYEWVMSDDYDSSIPKHREIAYNIEVGDGIPQMV 260
Query: 833 AYSDIAETAKKVGFEVVKEKDLA--APPAEPWW 925
D E KKVGF +++E DL P PW+
Sbjct: 261 RKCDAVEAIKKVGFNLLEEDDLTDHDNPDLPWY 293
>sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora lusitaniae
(strain ATCC 42720) GN=ERG6 PE=3 SV=1
Length = 375
Score = 211 bits (537), Expect = 1e-053
Identities = 108/264 (40%), Positives = 151/264 (57%), Gaps = 1/264 (0%)
Frame = +2
Query: 137 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 316
+++G AL S +K + E + + +YNLVTD YE+
Sbjct: 27 KKRGISALMAKAKEASDVATNGYFKHWDGGVSEDDEKKRLDDYSSLTKNYYNLVTDFYEY 86
Query: 317 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 496
GWG SFHFS +G++ R AT HE + + ++LDVGCGVGGP R I +
Sbjct: 87 GWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNINENMRVLDVGCGVGGPGREICRFTDC 146
Query: 497 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 676
+VG+ N+YQV+RA+ + +K LD V G+F+QM F+ +FD Y+IEAT HAP L
Sbjct: 147 TIVGLNNNDYQVERAQYYAKKYKLDDKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVL 206
Query: 677 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAET 856
E VY+EIY+VLKPG ++ YEWV TDK++ NEEH ++ GIE GD +P + +
Sbjct: 207 EGVYSEIYKVLKPGGVFGVYEWVMTDKYDENNEEHRKIAYGIEVGDGIPKMYKREVAEQA 266
Query: 857 AKKVGFEVVKEKDLAAPPAE-PWW 925
K VGF++ EKDLA E PW+
Sbjct: 267 LKNVGFDIEYEKDLADVNDEIPWY 290
>sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae
GN=ERG6 PE=1 SV=4
Length = 383
Score = 211 bits (537), Expect = 1e-053
Identities = 115/278 (41%), Positives = 162/278 (58%), Gaps = 4/278 (1%)
Frame = +2
Query: 137 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 316
++ G AL S E VQ + + + E E + ++YN+VTD YE+
Sbjct: 24 KKTGLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAEERRLEDYNEATHSYYNVVTDFYEY 83
Query: 317 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 496
GWG SFHFS +G+S + HE ++ G +LDVGCGVGGP R IA +
Sbjct: 84 GWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQRGDLVLDVGCGVGGPAREIARFTGC 143
Query: 497 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 676
NV+G+ N+YQ+ +A+ + +K L + V G+F++M F++NTFD Y+IEATCHAPKL
Sbjct: 144 NVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKL 203
Query: 677 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAET 856
E VY+EIY+VLKPG + YEWV TDK++ N EH ++ IE GD +P + + D+A
Sbjct: 204 EGVYSEIYKVLKPGGTFAVYEWVMTDKYDENNPEHRKIAYEIELGDGIPKM-FHVDVARK 262
Query: 857 A-KKVGFEVVKEKDLAAPPAE-PWWTRLKMGRLAYWRN 964
A K GFEV+ +DLA E PW+ L G Y +N
Sbjct: 263 ALKNCGFEVLVSEDLADNDDEIPWYYPL-TGEWKYVQN 299
>sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocystis carinii
GN=erg6 PE=2 SV=1
Length = 377
Score = 210 bits (532), Expect = 4e-053
Identities = 101/241 (41%), Positives = 153/241 (63%), Gaps = 3/241 (1%)
Frame = +2
Query: 284 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 463
+YNLVTD YE+GW SFHF + +S A HE ++ G+ +LDVGCGVGG
Sbjct: 80 YYNLVTDFYEYGWSTSFHFCRFAKDESFSQAIARHEHYIALHAGIREGETVLDVGCGVGG 139
Query: 464 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 643
P I+ + AN+VG+ N+YQ++RA+ ++ K GL + + G+F+QMPF +N+FD Y
Sbjct: 140 PACQISVFTGANIVGLNNNDYQIQRAKYYSEKKGLSDKLKFIKGDFMQMPFPENSFDKIY 199
Query: 644 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALP 823
SIEAT HAP LE VY+EIYRVLKPG LY SYEWV +K++ + EH +++ GIE GD++P
Sbjct: 200 SIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNKYDENDPEHQQIVYGIEIGDSIP 259
Query: 824 GLRAYSDIAETAKKVGFEVVKEKDLAAPPAE-PWWTRL--KMGRLAYWRNHIVVQVLSAV 994
+ + KVGFE++ ++L+ + PW+ L + ++ +R+ I + ++ +
Sbjct: 260 KISKIGEAEAALIKVGFEIIHSEELSTKNSPLPWYYYLDGDLRKVRSFRDFISIARMTTI 319
Query: 995 G 997
G
Sbjct: 320 G 320
>sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporthe grisea
GN=ERG6 PE=2 SV=2
Length = 390
Score = 208 bits (528), Expect = 1e-052
Identities = 117/289 (40%), Positives = 160/289 (55%), Gaps = 14/289 (4%)
Frame = +2
Query: 200 DNYKQYWSFFRRPKEIETA----EKVPDFVD---TFYNLVTDIYEWGWGQSFHFSPSIRG 358
D Y ++W + + ET E+ D+ +YNLVTD YE+GWGQSFHF G
Sbjct: 55 DQYFRHWD--GKTAKTETTKVREERKADYATLTRQYYNLVTDFYEYGWGQSFHFCTFAPG 112
Query: 359 KSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 538
++ A +E I +K G K+LD+GCGVGGP R IA + AN+ GITINEYQV+R
Sbjct: 113 ETFASAITRYEHTLAHRIGIKKGMKVLDIGCGVGGPARQIAKFTGANITGITINEYQVER 172
Query: 539 ARDHNRKAGLDA--LCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLK 712
AR + G A + V G+F+ +PF+ TFD YSIEAT HAPKLE+VY +I+ VLK
Sbjct: 173 ARRYAEMEGYGAGEQLKFVQGDFMALPFEKETFDAVYSIEATVHAPKLEDVYKQIFNVLK 232
Query: 713 PGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEK 892
PG ++ YEWV TD ++ + H E+ GIE G + L+ K GFE+++ +
Sbjct: 233 PGGIFGLYEWVMTDAYDENDPHHKEIRFGIEHGGGIANLQTAQTAIAAIKAAGFELLESE 292
Query: 893 DLA-APPAEPWWTRLKMGRLAYWRNHIVVQVLSAVGVAPKGTVDVHEML 1036
DLA PW+ L G A+ +LS + P G H +L
Sbjct: 293 DLADNSDRAPWYWPL--GGNAWQYASTFGDILSTFTMTPAGRAIAHTVL 339
>sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora crassa
GN=B24P7.240 PE=3 SV=1
Length = 379
Score = 202 bits (512), Expect = 8e-051
Identities = 103/230 (44%), Positives = 140/230 (60%), Gaps = 2/230 (0%)
Frame = +2
Query: 284 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 463
+YNL TDIYE+GWGQ FHF G+S A HE I +K K+LDVGCGVGG
Sbjct: 82 YYNLATDIYEYGWGQCFHFCRYSPGESFYQAIARHEHYLAAQIGIKKDMKVLDVGCGVGG 141
Query: 464 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 643
P R IA + A++ G+ N+YQ+ RA + + GL + V G+F+QM F DN+FD Y
Sbjct: 142 PAREIAKFTDAHITGLNNNDYQIDRATHYAVRDGLSGQLKFVKGDFMQMSFPDNSFDAVY 201
Query: 644 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALP 823
+IEAT HAPKLE VY EIYRVLKPG + YEW+ TD ++ +N EH ++ IE G+ +
Sbjct: 202 AIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDNYDNDNVEHRDIRLAIEVGNGIS 261
Query: 824 GLRAYSDIAETAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAYWRNHI 970
+ S+ K VGFE+V +DLA PW+ + G L Y ++++
Sbjct: 262 NMVTISEGLAAMKNVGFELVHHEDLADRNDPMPWYWPI-AGELRYMQSYL 310
>sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gossypii GN=ERG6
PE=3 SV=1
Length = 373
Score = 198 bits (501), Expect = 2e-049
Identities = 109/277 (39%), Positives = 152/277 (54%), Gaps = 8/277 (2%)
Frame = +2
Query: 137 ERKGKRALDLSGGSISAEKVQDNYKQYWSFFRRPKEIETAEKVPDF---VDTFYNLVTDI 307
ER G AL L + ++ Y ++W + E ++ D+ ++YN+VTD
Sbjct: 25 ERSGLTAL-LGKNREAQQEAVAKYLRHWDGATDAEAEE--RRLADYNESTHSYYNVVTDF 81
Query: 308 YEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASH 487
YE+GWG SFHFS G+S + HE + G +LDVGCGVGGP R IA
Sbjct: 82 YEYGWGASFHFSRFYTGESFAMSMARHEHYLAHRAGITSGDLVLDVGCGVGGPAREIARF 141
Query: 488 SRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHA 667
+ VVG+ N+YQ+ + + ++RK GL V G+F+ M F D TFD Y+IEATCHA
Sbjct: 142 TGCRVVGLNNNDYQIMKGKHYSRKLGLGDQVSYVKGDFMNMDFPDATFDKVYAIEATCHA 201
Query: 668 PKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDI 847
P E VY EIYRVLKPG ++ YEWV T+ ++ N EH + IE GD +P + +
Sbjct: 202 PSFEGVYGEIYRVLKPGGVFAVYEWVMTENYDETNPEHRRIAYDIELGDGIPKMYSVKVA 261
Query: 848 AETAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAY 955
+ KVGFE++ ++D A PW+ L G AY
Sbjct: 262 RDALAKVGFEILVDEDRADNDDPVPWYYPL-TGEWAY 297
>sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplastic
OS=Arabidopsis thaliana GN=G-TMT PE=2 SV=2
Length = 348
Score = 72 bits (176), Expect = 7e-012
Identities = 45/140 (32%), Positives = 66/140 (47%), Gaps = 6/140 (4%)
Frame = +2
Query: 341 SPSIRGKSHRDA-TRLHEEM-----AVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANV 502
S + H++A R+ EE D + K +K++DVGCG+GG R +AS A
Sbjct: 93 SVQLSDSGHKEAQIRMIEESLRFAGVTDEEEEKKIKKVVDVGCGIGGSSRYLASKFGAEC 152
Query: 503 VGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEE 682
+GIT++ Q KRA D L + L PF+D FD +S+E+ H P +
Sbjct: 153 IGITLSPVQAKRANDLAAAQSLAHKASFQVADALDQPFEDGKFDLVWSMESGEHMPDKAK 212
Query: 683 VYAEIYRVLKPGSLYVSYEW 742
E+ RV PG + W
Sbjct: 213 FVKELVRVAAPGGRIIIVTW 232
>sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltransferase 3
OS=Arabidopsis thaliana GN=NMT3 PE=2 SV=2
Length = 490
Score = 72 bits (174), Expect = 1e-011
Identities = 39/119 (32%), Positives = 62/119 (52%), Gaps = 2/119 (1%)
Frame = +2
Query: 401 VDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALC 580
VD++ +KPGQK+LDVGCG+GG +A + +VVGI ++ + A +H GL
Sbjct: 274 VDMLDLKPGQKVLDVGCGIGGGDFYMAENFDVDVVGIDLSVNMISFALEH--AIGLKCSV 331
Query: 581 EVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDK 757
E + + + DNTFD YS + H ++ Y+ LKPG + ++ + K
Sbjct: 332 EFEVADCTKKEYPDNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPK 390
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,436,365,428
Number of Sequences: 518415
Number of Extensions: 75436365428
Number of Successful Extensions: 513409628
Number of sequences better than 0.0: 0
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