BLASTX 7.6.2
Query= UN18271 /QuerySize=1240
(1239 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54WI4|SAE1_DICDI SUMO-activating enzyme subunit 1 OS=Dictyos... 171 1e-041
sp|Q8JGT5|SAE1_XENLA SUMO-activating enzyme subunit 1 OS=Xenopus... 115 8e-025
sp|Q28DS0|SAE1_XENTR SUMO-activating enzyme subunit 1 OS=Xenopus... 114 2e-024
sp|Q6AXQ0|SAE1_RAT SUMO-activating enzyme subunit 1 OS=Rattus no... 111 1e-023
sp|Q9R1T2|SAE1_MOUSE SUMO-activating enzyme subunit 1 OS=Mus mus... 111 2e-023
sp|Q6IQS6|SAE1_DANRE SUMO-activating enzyme subunit 1 OS=Danio r... 110 3e-023
sp|Q9UBE0|SAE1_HUMAN SUMO-activating enzyme subunit 1 OS=Homo sa... 109 4e-023
sp|Q5NVN7|SAE1_PONAB SUMO-activating enzyme subunit 1 OS=Pongo a... 109 4e-023
sp|A2VE14|SAE1_BOVIN SUMO-activating enzyme subunit 1 OS=Bos tau... 107 2e-022
sp|Q06624|RHC31_YEAST DNA damage tolerance protein RHC31 OS=Sacc... 104 2e-021
sp|Q55C16|UBA1_DICDI Ubiquitin-like modifier-activating enzyme 1... 94 1e-018
sp|P20973|UBE11_WHEAT Ubiquitin-activating enzyme E1 1 OS=Tritic... 92 7e-018
sp|P31251|UBE12_WHEAT Ubiquitin-activating enzyme E1 2 OS=Tritic... 89 6e-017
sp|P79064|RAD31_SCHPO DNA damage tolerance protein rad31 OS=Schi... 84 1e-015
sp|O94609|UBA1_SCHPO Ubiquitin-activating enzyme E1 1 OS=Schizos... 82 9e-015
sp|A0AVT1|UBA6_HUMAN Ubiquitin-like modifier-activating enzyme 6... 82 9e-015
sp|Q54JM3|ULA1_DICDI NEDD8-activating enzyme E1 regulatory subun... 80 3e-014
sp|P31252|UBE13_WHEAT Ubiquitin-activating enzyme E1 3 OS=Tritic... 79 5e-014
sp|Q17820|SAE1_CAEEL SUMO-activating enzyme subunit aos-1 OS=Cae... 78 1e-013
>sp|Q54WI4|SAE1_DICDI SUMO-activating enzyme subunit 1 OS=Dictyostelium
discoideum GN=sae1 PE=3 SV=1
Length = 330
Score = 171 bits (432), Expect = 1e-041
Identities = 107/321 (33%), Positives = 164/321 (51%), Gaps = 17/321 (5%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G+ LTE E +YDR IR+WG +AQ +L +S +L GI G ++E KN+VLAGV S+TL+D
Sbjct: 16 GKGLTEYEAKIYDRSIRLWGVDAQAKLRQSKVLFIGINGLMSEIIKNVVLAGVDSITLVD 75
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
D ++ L+A+ I D GK ++ ++ + NP+V + V ++ + +F +
Sbjct: 76 DHIITTSDLSAHLFINEDS---VGKVISTESVFAISELNPLVTIDVYDKEIETMDDQFIK 132
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKKLEEK 615
+ +VVI +L VN CRK V+F G F DL ++KY K E
Sbjct: 133 NYTMVVISDKNLNNVSKVNSLCRK--NNVSFIFSHSFGLKGLFFSDLNEFKYFTKTTTEP 190
Query: 616 VECELN---FPSFQEAVSVPWKPIPRRTAKLYFAMRVIEVFEENEGRKHGECSLLDLPTV 786
+ E + F SF+E++ W RT +FA+ + FEE R S DL +
Sbjct: 191 PKTETHISIFKSFKESMGYDWSKTNSRTPLPFFALSTLYQFEEKHNRVPDNISDSDLSEL 250
Query: 787 LEIKKKLCE----ANAVSESHVPDS--LLERLITGTIEFPPACAIIGGILAQEVIKAVSG 948
I E N S + ++ LL ++ IE P CAI+GGI+ E+IK ++
Sbjct: 251 KSIINSSIEKFNLKNTDSNKYFEETKDLLNKM---NIEISPVCAIVGGIVGAEIIKIITQ 307
Query: 949 KGEPLKNFFYYDAQDGKGVME 1011
+ L NFF+YD G G++E
Sbjct: 308 NMQVLNNFFFYDGVKGTGLVE 328
>sp|Q8JGT5|SAE1_XENLA SUMO-activating enzyme subunit 1 OS=Xenopus laevis GN=sae1
PE=2 SV=1
Length = 344
Score = 115 bits (287), Expect = 8e-025
Identities = 63/173 (36%), Positives = 101/173 (58%), Gaps = 5/173 (2%)
Frame = +1
Query: 85 LTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMDDSL 264
++E+E A YDRQIR+WG AQ+RL S +L+ G++G AE KN++LAGV ++TL+D
Sbjct: 9 ISEEEAAQYDRQIRLWGLEAQKRLRTSRVLLVGMRGLGAEVAKNLILAGVKALTLLDHEQ 68
Query: 265 VNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFEKFD 444
V+ E A FLIP + G+ AE + ++ NPMV V + +++ ++ +FF +FD
Sbjct: 69 VSSEDSRAQFLIP---SGSLGQNRAEASLNRARNLNPMVSVEADTENINQKSDDFFTQFD 125
Query: 445 VVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKK 603
VV + VN C K + F+T D G +F DL ++++ ++K
Sbjct: 126 VVCLTSCPSDLLVRVNHICHK--HNIKFFTGDVYGYHGSMFADLGEHEFVEEK 176
>sp|Q28DS0|SAE1_XENTR SUMO-activating enzyme subunit 1 OS=Xenopus tropicalis
GN=sae1 PE=2 SV=1
Length = 347
Score = 114 bits (284), Expect = 2e-024
Identities = 63/173 (36%), Positives = 102/173 (58%), Gaps = 5/173 (2%)
Frame = +1
Query: 85 LTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMDDSL 264
++E+E A YDRQIR+WG AQ+RL S +L+ G++G AE KN++LAGV ++TL+D
Sbjct: 9 ISEEEAAQYDRQIRLWGLEAQKRLRTSRVLLVGMRGLGAEVAKNLILAGVKALTLLDHEQ 68
Query: 265 VNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFEKFD 444
V+ E A FLIP + G+ AE + ++ NPMV V + +++ ++ +FF +FD
Sbjct: 69 VSSEDSRAQFLIP---SGSLGQNRAEASLNRARNLNPMVSVEADTENINQKSDDFFTQFD 125
Query: 445 VVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKK 603
VV + S V+ C K + F+T D G +F DL ++++ ++K
Sbjct: 126 VVCLTSCSRDLLVRVDHICHK--HNIKFFTGDVFGYHGYMFADLGEHEFVEEK 176
>sp|Q6AXQ0|SAE1_RAT SUMO-activating enzyme subunit 1 OS=Rattus norvegicus
GN=Sae1 PE=2 SV=1
Length = 349
Score = 111 bits (276), Expect = 1e-023
Identities = 64/176 (36%), Positives = 99/176 (56%), Gaps = 5/176 (2%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G ++E+E A YDRQIR+WG AQ+RL S +L+ G+KG AE KN++LAGV +T++D
Sbjct: 11 GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLD 70
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
V+ E L A FLI G+ AE + ++ NPMV V V+ D+ + FF
Sbjct: 71 HEQVSPEDLGAQFLI---RTGSVGQNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFT 127
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKK 603
+FD V + S V++ C + S + F+T D G F +L ++++ ++K
Sbjct: 128 EFDAVCLTCCSKDVIIKVDQICHRNS--IKFFTGDVFGYHGYTFANLGEHEFVEEK 181
>sp|Q9R1T2|SAE1_MOUSE SUMO-activating enzyme subunit 1 OS=Mus musculus GN=Sae1
PE=2 SV=1
Length = 350
Score = 111 bits (275), Expect = 2e-023
Identities = 64/176 (36%), Positives = 99/176 (56%), Gaps = 5/176 (2%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G ++E+E A YDRQIR+WG AQ+RL S +L+ G+KG AE KN++LAGV +T++D
Sbjct: 12 GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLD 71
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
V+ E A FLI + G+ AE + ++ NPMV V V+ D+ + FF
Sbjct: 72 HEQVSPEDPGAQFLI---QTGSVGRNRAEASLERAQNLNPMVDVKVDTEDVEKKPESFFT 128
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKK 603
KFD V + S V++ C + S + F+T D G F +L ++++ ++K
Sbjct: 129 KFDAVCLTCCSRDVIIKVDQICHRNS--IKFFTGDVFGYHGYTFANLGEHEFVEEK 182
>sp|Q6IQS6|SAE1_DANRE SUMO-activating enzyme subunit 1 OS=Danio rerio GN=sae1
PE=2 SV=1
Length = 348
Score = 110 bits (273), Expect = 3e-023
Identities = 65/174 (37%), Positives = 100/174 (57%), Gaps = 6/174 (3%)
Frame = +1
Query: 85 LTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMDDSL 264
++E+E A YDRQIR+WG +AQ+RL S +L+ G++G AE KN++LAGV +TL+D
Sbjct: 12 ISEEEAAQYDRQIRLWGLDAQKRLRGSRVLLVGLRGLGAEVAKNLILAGVKGLTLLDHEQ 71
Query: 265 VNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFEKFD 444
V EES A FLIP D + G+ A+ + + NPMV V + + ++ +FF +FD
Sbjct: 72 VTEESRRAQFLIPVDAD---GQNHAQASLERAQFLNPMVEVKADTEPVESKPDDFFFQFD 128
Query: 445 VVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDL-QDYKYTKKK 603
V + S V++ C S+ + + D G +F DL Q+Y Y ++K
Sbjct: 129 AVCLTRCSRDLMVRVDQLC--ASRNIKVFCGDVYGYNGYMFSDLGQEYHYVEEK 180
>sp|Q9UBE0|SAE1_HUMAN SUMO-activating enzyme subunit 1 OS=Homo sapiens GN=SAE1
PE=1 SV=1
Length = 346
Score = 109 bits (272), Expect = 4e-023
Identities = 64/176 (36%), Positives = 97/176 (55%), Gaps = 5/176 (2%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G ++E+E A YDRQIR+WG AQ+RL S +L+ G+KG AE KN++LAGV +T++D
Sbjct: 8 GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLD 67
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
V E A FLI G+ AE + ++ NPMV V V+ D+ + FF
Sbjct: 68 HEQVTPEDPGAQFLI---RTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFT 124
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKK 603
+FD V + S V++ C K S + F+T D G F +L ++++ ++K
Sbjct: 125 QFDAVCLTCCSRDVIVKVDQICHKNS--IKFFTGDVFGYHGYTFANLGEHEFVEEK 178
>sp|Q5NVN7|SAE1_PONAB SUMO-activating enzyme subunit 1 OS=Pongo abelii GN=SAE1
PE=2 SV=2
Length = 346
Score = 109 bits (272), Expect = 4e-023
Identities = 64/176 (36%), Positives = 97/176 (55%), Gaps = 5/176 (2%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G ++E+E A YDRQIR+WG AQ+RL S +L+ G+KG AE KN++LAGV +T++D
Sbjct: 8 GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLD 67
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
V E A FLI G+ AE + ++ NPMV V V+ D+ + FF
Sbjct: 68 HEQVTPEDPGAQFLI---RTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFT 124
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKK 603
+FD V + S V++ C K S + F+T D G F +L ++++ ++K
Sbjct: 125 QFDAVCLTCCSRDVIVKVDQICHKNS--IKFFTGDVFGYHGYTFANLGEHEFVEEK 178
>sp|A2VE14|SAE1_BOVIN SUMO-activating enzyme subunit 1 OS=Bos taurus GN=SAE1
PE=2 SV=1
Length = 346
Score = 107 bits (267), Expect = 2e-022
Identities = 63/176 (35%), Positives = 98/176 (55%), Gaps = 5/176 (2%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G ++E+E A YDRQIR+WG AQ+RL S +L+ G+KG AE KN++LAGV +T++D
Sbjct: 8 GGGISEEEAAQYDRQIRLWGLEAQKRLRASQVLLVGMKGLGAEIAKNLILAGVKGLTMLD 67
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
V+ E A FLI G+ AE + ++ NPMV V V+ ++ + FF
Sbjct: 68 HEQVSPEDPGAQFLI---RTGSVGRNRAEASLERAQNLNPMVDVKVDTENIEKKPESFFT 124
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKK 603
+FD V + S V++ C K S + F+T D G F +L ++++ ++K
Sbjct: 125 QFDAVCLTCCSRDVIVKVDQICHKNS--IKFFTGDVFGYHGYTFANLGEHEFVEEK 178
Score = 76 bits (186), Expect = 4e-013
Identities = 44/138 (31%), Positives = 76/138 (55%), Gaps = 9/138 (6%)
Frame = +1
Query: 616 VECELNFPSFQEAVSVPW-----KPIPRRTAKLYFAMRVIEVFEENEGRKHGECSL-LDL 777
V+ ++ F S +EA+ V W K +RT YF ++V+ F ++GR + D
Sbjct: 207 VKKKVVFCSVKEALEVDWSSDKAKAALKRTTPDYFLLQVLLKFRTDKGRDPSSDTFGEDS 266
Query: 778 PTVLEIKKKLCEANAVSESHVPDSLLERLITGTIEFPPACAIIGGILAQEVIKAVSGKGE 957
+L+I+ + +A V+ +P+ + + E P CA++GGILAQE++KA+S +
Sbjct: 267 ELLLQIRNDVLDALGVNPDLLPEDFVRYCFS---EMAPVCAVVGGILAQEIVKALSQRDP 323
Query: 958 PLKNFFYYDAQDGKGVME 1011
P NFF++D G G++E
Sbjct: 324 PHNNFFFFDGMKGNGIVE 341
>sp|Q06624|RHC31_YEAST DNA damage tolerance protein RHC31 OS=Saccharomyces
cerevisiae GN=AOS1 PE=1 SV=1
Length = 347
Score = 104 bits (258), Expect = 2e-021
Identities = 57/180 (31%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Frame = +1
Query: 70 MDGEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTL 249
M E+L+E E ALYDRQIR+WG AQ + + +L+ + +E K+IVL+G+G +T+
Sbjct: 3 MKVEKLSEDEIALYDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGIGHLTI 62
Query: 250 MDDSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEF 429
+D +V EE L + F I ++ G+ + + ++D NP + ++ +K DL ++ EF
Sbjct: 63 LDGHMVTEEDLGSQFFIGSED---VGQWKIDATKERIQDLNPRIELNFDKQDLQEKDEEF 119
Query: 430 FEKFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKKLE 609
F++FD+VV + +N RKL+ + Y +F+DL ++ +KL+
Sbjct: 120 FQQFDLVVATEMQIDEAIKINTLTRKLN--IPLYVAGSNGLFAYVFIDLIEFISEDEKLQ 177
>sp|Q55C16|UBA1_DICDI Ubiquitin-like modifier-activating enzyme 1
OS=Dictyostelium discoideum GN=uba1 PE=3 SV=1
Length = 1017
Score = 94 bits (233), Expect = 1e-018
Identities = 58/168 (34%), Positives = 92/168 (54%), Gaps = 7/168 (4%)
Frame = +1
Query: 70 MDGEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTL 249
MD E+ + + ALY RQ+ +++T + +LV G++G E K++ LAGV SVTL
Sbjct: 5 MDVEQEPKIDDALYSRQLYALSHETMKKITSTSVLVVGLQGLGIEIVKDLSLAGVKSVTL 64
Query: 250 MDDSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEF 429
D LV + L++ F P++ G+ A+ C + D N V + V G+LS EF
Sbjct: 65 YDKELVEIKDLSSQFYFSPEQVGKVGR--ADACFQKVVDLNNYVRIDVHNGELS---DEF 119
Query: 430 FEKFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVD 573
+KF+VVV+ LA + VNE C + ++ F +V+ R G++F D
Sbjct: 120 LKKFNVVVLANQPLALQLKVNEFCH--ANKIHFISVETRGVFGQLFND 165
>sp|P20973|UBE11_WHEAT Ubiquitin-activating enzyme E1 1 OS=Triticum aestivum
GN=UBA1 PE=1 SV=1
Length = 1051
Score = 92 bits (227), Expect = 7e-018
Identities = 61/166 (36%), Positives = 86/166 (51%), Gaps = 9/166 (5%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G E+ E L+ RQ+ V+G +RL S++LVSG++G AE KN+VLAGV SVTL D
Sbjct: 40 GNEIDED---LHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAKNLVLAGVKSVTLHD 96
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
D V L++NF + ++ G+ A+ C L++ N VLVS GDL+ E
Sbjct: 97 DGNVELWDLSSNFFLSEND---VGQNRAQACVQKLQELNNAVLVSALTGDLT---KEHLS 150
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVD 573
KF VV SL ++ C +AF + R G +F D
Sbjct: 151 KFQAVVFTDISLDKAIEFDDYCHSQQPPIAFIKSEVRGLFGSVFCD 196
>sp|P31251|UBE12_WHEAT Ubiquitin-activating enzyme E1 2 OS=Triticum aestivum
GN=UBA2 PE=2 SV=1
Length = 1051
Score = 89 bits (219), Expect = 6e-017
Identities = 60/166 (36%), Positives = 85/166 (51%), Gaps = 9/166 (5%)
Frame = +1
Query: 76 GEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMD 255
G E+ E L+ RQ+ V+G + L S++LVSG++G AE KN+VLAGV SVTL D
Sbjct: 40 GNEIDED---LHSRQLAVYGRETMKPLFGSNVLVSGLQGLGAEIAKNLVLAGVKSVTLHD 96
Query: 256 DSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFE 435
D V L++NF + ++ G+ A+ C L++ N VLVS GDL+ E
Sbjct: 97 DGNVELWDLSSNFFLSEND---VGQNRAQACVQKLQELNNAVLVSALTGDLT---KEHLS 150
Query: 436 KFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVD 573
KF VV SL ++ C +AF + R G +F D
Sbjct: 151 KFQAVVFTDISLDKAIEFDDYCHSHQPPIAFIKSEVRGLFGSVFCD 196
>sp|P79064|RAD31_SCHPO DNA damage tolerance protein rad31 OS=Schizosaccharomyces
pombe GN=rad31 PE=2 SV=1
Length = 307
Score = 84 bits (207), Expect = 1e-015
Identities = 57/216 (26%), Positives = 100/216 (46%), Gaps = 5/216 (2%)
Frame = +1
Query: 70 MDGEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTL 249
M + +E ALYDRQIR+WG NAQ+ L +S +L+ E KN+VL+G+G + +
Sbjct: 1 MGNHNINAEEIALYDRQIRLWGFNAQQALKQSRVLLITASPLANEIAKNLVLSGIGKLCV 60
Query: 250 MDDSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEF 429
+D V E+ + F I E + G+ A + L + NP+V + + +S +
Sbjct: 61 LDSMTVYEKDVEEQFFI---EASDIGQLRANVFKKKLHELNPLVEIDTDTSLISEIDEGK 117
Query: 430 FEKFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKKKLE 609
KF +V+ +NE R + +FY C G F DL ++ + ++
Sbjct: 118 ISKFSMVIATQLDYEEFCRINELTRICN--ASFYATSCFGLYGFAFCDLINHNFAIDRVV 175
Query: 610 EKVECELNFPSFQEAVSVPWKPIPRRTAKLYFAMRV 717
+ + E + Q+ + ++ I T K A ++
Sbjct: 176 DNTKVEEDMFIVQKPMKEAFQSILGETLKPRLAKKI 211
>sp|O94609|UBA1_SCHPO Ubiquitin-activating enzyme E1 1 OS=Schizosaccharomyces
pombe GN=ptr3 PE=1 SV=1
Length = 1012
Score = 82 bits (200), Expect = 9e-015
Identities = 53/171 (30%), Positives = 85/171 (49%), Gaps = 9/171 (5%)
Frame = +1
Query: 61 NLRMDGEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGS 240
N+ +D + + LY RQ+ V G A +++++S++L+ G KG E KN+ LAGV S
Sbjct: 4 NMNIDQTDQNTIDEGLYSRQLYVLGHEAMKQMSQSNVLIIGCKGLGVEIAKNVCLAGVKS 63
Query: 241 VTLMDDSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARN 420
VTL D E L++ + + D+ G A++ L + N V VSV + +
Sbjct: 64 VTLYDPQPTRIEDLSSQYFLTEDD---IGVPRAKVTVSKLAELNQYVPVSV----VDELS 116
Query: 421 TEFFEKFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVD 573
TE+ + F VV+ SL + +N+ K +A+ D R G IF D
Sbjct: 117 TEYLKNFKCVVVTETSLTKQLEINDFTHK--NHIAYIAADSRGLFGSIFCD 165
>sp|A0AVT1|UBA6_HUMAN Ubiquitin-like modifier-activating enzyme 6 OS=Homo
sapiens GN=UBA6 PE=1 SV=1
Length = 1052
Score = 82 bits (200), Expect = 9e-015
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 2/175 (1%)
Frame = +1
Query: 61 NLRMDGEELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGS 240
NL + E + ALY RQ V G A +++ KSH+ +SG+ G E KN+VLAG+ +
Sbjct: 28 NLPIMSTASVEIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKA 87
Query: 241 VTLMDDSLVNEESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLS-AR 417
VT+ D L NF + D+ K + AE + + NP V V+ +
Sbjct: 88 VTIHDTEKCQAWDLGTNFFLSEDDVVNK-RNRAEAVLKHIAELNPYVHVTSSSVPFNETT 146
Query: 418 NTEFFEKFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQD 582
+ F +K+ VV+ L +K +N+ CR + F + D +F D D
Sbjct: 147 DLSFLDKYQCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGD 201
>sp|Q54JM3|ULA1_DICDI NEDD8-activating enzyme E1 regulatory subunit
OS=Dictyostelium discoideum GN=nae1 PE=3 SV=1
Length = 520
Score = 80 bits (196), Expect = 3e-014
Identities = 48/122 (39%), Positives = 69/122 (56%), Gaps = 6/122 (4%)
Frame = +1
Query: 97 ETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMDDSLVNEE 276
+T YDRQ+R+WG + Q +L +SHIL+ T E KN+VL G+GS T++D+ V E
Sbjct: 7 DTDKYDRQLRLWGEDGQSKLERSHILLLNGSATGTETLKNLVLPGIGSFTVVDNKKVTES 66
Query: 277 SLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVL-VSVEKG--DLSARNTEFFEKFDV 447
L NF + E + GK A + C+ L++ N V SVE+ L N FF+ F +
Sbjct: 67 DLGNNFFV---ERSSLGKPRATVVCELLRELNDRVKGFSVEECPIHLINNNISFFKDFSL 123
Query: 448 VV 453
VV
Sbjct: 124 VV 125
>sp|P31252|UBE13_WHEAT Ubiquitin-activating enzyme E1 3 OS=Triticum aestivum
GN=UBA3 PE=2 SV=1
Length = 1053
Score = 79 bits (194), Expect = 5e-014
Identities = 54/161 (33%), Positives = 76/161 (47%), Gaps = 6/161 (3%)
Frame = +1
Query: 91 EQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMDDSLVN 270
E + L+ RQ+ V+G RRL S +LVSG+ G AE KN+ LAGV SVT+ D V
Sbjct: 45 EIDEDLHSRQLAVYGRETMRRLFASDVLVSGLNGLGAEIAKNLALAGVKSVTIHDVKTVK 104
Query: 271 EESLNANFLIPPDENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARNTEFFEKFDVV 450
L+ NF + D+ GK A C L++ N VL+S +L+ TE KF V
Sbjct: 105 MWDLSGNFFLSEDD---IGKNRAAACVAKLQELNNAVLISALTEELT---TEHLSKFQAV 158
Query: 451 VIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVD 573
V L ++ C ++F + G +F D
Sbjct: 159 VFTDIDLDKAYEFDDYCHNHQPPISFIKSEVCGLFGSVFCD 199
>sp|Q17820|SAE1_CAEEL SUMO-activating enzyme subunit aos-1 OS=Caenorhabditis
elegans GN=aos-1 PE=2 SV=1
Length = 343
Score = 78 bits (191), Expect = 1e-013
Identities = 57/178 (32%), Positives = 87/178 (48%), Gaps = 9/178 (5%)
Frame = +1
Query: 82 ELTEQETALYDRQIRVWGANAQRRLTKSHILVSGIKGTVAEFCKNIVLAGVGSVTLMDDS 261
E+++ E A+YDRQIR+WG AQ ++ S +L+ G K AE K + LAGV + L+D
Sbjct: 2 EVSKAEQAIYDRQIRLWGMEAQNKIRNSKVLIIGGKQLGAEVAKTLSLAGVDEMHLVDHR 61
Query: 262 LVNEESLNANFLIPPD-ENAYKGKTVAEICCDSLKDFNPMVLVSVEKGDLSARN----TE 426
LV+ E + NFL +N+ K A + L + N V + + + D+ ++N E
Sbjct: 62 LVDTEEIGMNFLYDASVDNSKMTKWAASY--NFLYNLNRNVKLFIVEEDVLSKNDSEIEE 119
Query: 427 FFEKFDVVVIGYGSLATKKAVNEKCRKLSKRVAFYTVDCRDSCGEIFVDLQDYKYTKK 600
+ KF +VV+ S VN CRK + F + G F D + Y K
Sbjct: 120 YLTKFTLVVVLDESYERTAKVNNICRK--HHIRFISGAIYGWIGYAFFDFDGHAYLVK 175
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,436,365,428
Number of Sequences: 518415
Number of Extensions: 75436365428
Number of Successful Extensions: 513409628
Number of sequences better than 0.0: 0
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