BLASTX 7.6.2
Query= UN18504 /QuerySize=2003
(2002 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9SZ30|HIS5_ARATH Imidazole glycerol phosphate synthase hisHF... 1070 4e-312
sp|Q9P4P9|HIS5_EMENI Imidazole glycerol phosphate synthase hisHF... 433 3e-120
sp|O94303|HIS5_SCHPO Imidazole glycerol phosphate synthase hisHF... 431 9e-120
sp|P33734|HIS5_YEAST Imidazole glycerol phosphate synthase hisHF... 396 3e-109
sp|Q92E86|HIS5_LISIN Imidazole glycerol phosphate synthase subun... 167 3e-040
sp|Q7ULP3|HIS5_RHOBA Imidazole glycerol phosphate synthase subun... 163 6e-039
sp|A8AY26|HIS5_STRGC Imidazole glycerol phosphate synthase subun... 162 1e-038
sp|A3CNT2|HIS5_STRSV Imidazole glycerol phosphate synthase subun... 160 5e-038
sp|C1L0J4|HIS5_LISMC Imidazole glycerol phosphate synthase subun... 155 2e-036
sp|Q722Y5|HIS5_LISMF Imidazole glycerol phosphate synthase subun... 155 2e-036
sp|Q8Y9G3|HIS5_LISMO Imidazole glycerol phosphate synthase subun... 153 6e-036
sp|B8DA60|HIS5_LISMH Imidazole glycerol phosphate synthase subun... 152 1e-035
sp|A5UMZ1|HIS6_METS3 Imidazole glycerol phosphate synthase subun... 146 1e-033
sp|Q2NI84|HIS6_METST Imidazole glycerol phosphate synthase subun... 133 5e-030
sp|O27398|HIS6_METTH Imidazole glycerol phosphate synthase subun... 129 9e-029
sp|Q8TYW8|HIS6_METKA Imidazole glycerol phosphate synthase subun... 125 2e-027
sp|Q0W358|HIS6_UNCMA Imidazole glycerol phosphate synthase subun... 119 7e-026
sp|Q8R885|HIS6_THETN Imidazole glycerol phosphate synthase subun... 116 6e-025
sp|Q3INY2|HIS6_NATPD Imidazole glycerol phosphate synthase subun... 116 8e-025
sp|O29439|HIS6_ARCFU Imidazole glycerol phosphate synthase subun... 115 1e-024
>sp|Q9SZ30|HIS5_ARATH Imidazole glycerol phosphate synthase hisHF, chloroplastic
OS=Arabidopsis thaliana GN=At4g26900 PE=1 SV=1
Length = 592
Score = 1070 bits (2767), Expect = 4e-312
Identities = 542/594 (91%), Positives = 560/594 (94%), Gaps = 9/594 (1%)
Frame = +1
Query: 40 MDATTAAAPFSSFTTSRQNLS-------SSPCSSLLSRKKLGSTNLKFKSPRSLSVRASP 198
M+AT AAPFSS +SRQN S SSP S LS+K +G+ N KFKSPRSLSVRAS
Sbjct: 1 MEAT--AAPFSSIVSSRQNFSSSSSIRASSPASLFLSQKSIGNVNRKFKSPRSLSVRASS 58
Query: 199 TSDSVVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVL 378
TSDSVVTLLDYGAGNVRSIRNALRHLGFSIKDV+TPGDILNADRLIFPGVGAFAPAMDVL
Sbjct: 59 TSDSVVTLLDYGAGNVRSIRNALRHLGFSIKDVQTPGDILNADRLIFPGVGAFAPAMDVL 118
Query: 379 NKTGMGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRV 558
N+TGM EALC YIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPG VGRFD+SAGIRV
Sbjct: 119 NRTGMAEALCKYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGIVGRFDASAGIRV 178
Query: 559 PHIGWNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRG 738
PHIGWNALQVG DSEILDDVGNRHVYFVHSYRAIPS ENKDWISSTC+YGESFISSIRRG
Sbjct: 179 PHIGWNALQVGKDSEILDDVGNRHVYFVHSYRAIPSDENKDWISSTCNYGESFISSIRRG 238
Query: 739 NVHAVQFHPEKSGEVGLSVLRRFLDPKSPSKQKPMEGKASKLAKRVIACLDVRTNDKGDL 918
NVHAVQFHPEKSGEVGLSVLRRFL PK P+ QKPMEGKASKLAKRVIACLDVRTNDKGDL
Sbjct: 239 NVHAVQFHPEKSGEVGLSVLRRFLHPKLPATQKPMEGKASKLAKRVIACLDVRTNDKGDL 298
Query: 919 VVTKGDQYDVREQSNENEVRNLGKPVDLAGQYYKDGADEISFLNITGFRDFPLGDLPMIR 1098
VVTKGDQYDVREQSNENEVRNLGKPVDLAGQYYKDGADEISFLNITGFRDFPLGDLPMI+
Sbjct: 299 VVTKGDQYDVREQSNENEVRNLGKPVDLAGQYYKDGADEISFLNITGFRDFPLGDLPMIQ 358
Query: 1099 VLRYTSENVFVPLTVGGGIRDFTDATGRYYSSLEVAAEYFRSGADKISIGSDAVYAAEEF 1278
VLR TS+NVFVPLTVGGGIRDFTDA+GRYYSSLEVAAEYFRSGADKISIGSDAV AAEEF
Sbjct: 359 VLRQTSKNVFVPLTVGGGIRDFTDASGRYYSSLEVAAEYFRSGADKISIGSDAVSAAEEF 418
Query: 1279 IKSGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAW 1458
IKSGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVNHP+DVPYKVIRVTNPGPNGEEYAW
Sbjct: 419 IKSGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVNHPDDVPYKVIRVTNPGPNGEEYAW 478
Query: 1459 YQCTVSGGREGRPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIP 1638
YQCTVSGGREGRPIGA+ELAKAVEELGAGEILLNCIDCDGQGKGFD DLVKLISD VGIP
Sbjct: 479 YQCTVSGGREGRPIGAFELAKAVEELGAGEILLNCIDCDGQGKGFDIDLVKLISDSVGIP 538
Query: 1639 VIASSGAGTPEHFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVRM 1800
VIASSGAGTP+HFSEVFE TNASAALAAGIFHRKEVPIQSVKEHL E+ IEVR+
Sbjct: 539 VIASSGAGTPDHFSEVFEKTNASAALAAGIFHRKEVPIQSVKEHLQEERIEVRI 592
>sp|Q9P4P9|HIS5_EMENI Imidazole glycerol phosphate synthase hisHF OS=Emericella
nidulans GN=hisHF PE=3 SV=2
Length = 553
Score = 433 bits (1112), Expect = 3e-120
Identities = 222/400 (55%), Positives = 283/400 (70%), Gaps = 12/400 (3%)
Frame = +1
Query: 634 YFVHSYRA--IPSSENKD-WISSTCHYG-ESFISSIRRGNVHAVQFHPEKSGEVGLSVLR 801
Y+VHSY A P KD W+ +T YG E FI +I R N+ A QFHPEKSG+ GL LR
Sbjct: 148 YYVHSYAAPYEPGILEKDGWLVATASYGEEKFIGAIARDNIFATQFHPEKSGQAGLRTLR 207
Query: 802 RFLDPKS----PSKQKPMEGKASKLAKRVIACLDVRTNDKGDLVVTKGDQYDVREQSNEN 969
FLD + + G+ + L +R+IACLDVRTND GDLVVTKGDQYDVRE+ +
Sbjct: 208 AFLDGAQLHSVTLEDSILTGEKNGLTRRIIACLDVRTNDVGDLVVTKGDQYDVREKDGAD 267
Query: 970 ---EVRNLGKPVDLAGQYYKDGADEISFLNITGFRDFPLGDLPMIRVLRYTSENVFVPLT 1140
+VRNLGKPVD+A +YY+ GADE++FLNIT FR+ PL DLPM+ +LR TSE VFVPLT
Sbjct: 268 AGGQVRNLGKPVDMAKKYYEQGADEVTFLNITSFRNCPLADLPMLEILRRTSETVFVPLT 327
Query: 1141 VGGGIRDFTDATGRYYSSLEVAAEYFRSGADKISIGSDAVYAAEEFIKSG-VKTGKSSLE 1317
+GGGIRD D G + +L+VA+ YF+SGADK+SIGSDAV AAE++ +G V +GK+++E
Sbjct: 328 IGGGIRDTVDTDGTHIPALDVASMYFKSGADKVSIGSDAVVAAEDYYAAGKVLSGKTAIE 387
Query: 1318 QISRVYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAWYQCTVSGGREGRP 1497
IS+ YGNQAVVVS+DP+RVYV+ PED ++ I P G+ + WYQCT+ GGRE R
Sbjct: 388 TISKAYGNQAVVVSVDPKRVYVSQPEDTKHRTIETKFPNAAGQNFCWYQCTIKGGRETRD 447
Query: 1498 IGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGTPEHF 1677
+ +L +AVE +GAGEILLNCID DG GFD +L+ + V IPVIASSGAG P+HF
Sbjct: 448 LDVCQLVQAVEAMGAGEILLNCIDKDGSNSGFDLELINHVKAAVKIPVIASSGAGMPKHF 507
Query: 1678 SEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVR 1797
EVF+ T AAL AG+FHR E + VK++L ++ VR
Sbjct: 508 EEVFDQTTTDAALGAGMFHRGEYTVGEVKQYLEDRGFLVR 547
>sp|O94303|HIS5_SCHPO Imidazole glycerol phosphate synthase hisHF
OS=Schizosaccharomyces pombe GN=his4 PE=2 SV=3
Length = 541
Score = 431 bits (1108), Expect = 9e-120
Identities = 219/396 (55%), Positives = 284/396 (71%), Gaps = 8/396 (2%)
Frame = +1
Query: 628 HVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHAVQFHPEKSGEVGLSVLRRF 807
H Y + I E K I++T + E+F+ +I + N A QFHPEKSG GL L+ F
Sbjct: 147 HSYMIPEKGLILPPEFK--IATTKYGNETFVGAIVKNNFLATQFHPEKSGSAGLRCLKAF 204
Query: 808 L-----DPKSPSKQKPMEGKASKLAKRVIACLDVRTNDKGDLVVTKGDQYDVREQSNENE 972
L P S K +E L KR+IACLDVR+ND GDLVVTKGDQYDVRE+S+ +E
Sbjct: 205 LTGNYEQPISGEASKLIENSFGGLTKRIIACLDVRSNDAGDLVVTKGDQYDVREKSSGSE 264
Query: 973 VRNLGKPVDLAGQYYKDGADEISFLNITGFRDFPLGDLPMIRVLRYTSENVFVPLTVGGG 1152
VRNLGKPV+L +Y+++GADE+ FLNIT FR+ P+ D PM++VL ++ VFVPLTVGGG
Sbjct: 265 VRNLGKPVELCQRYFQEGADEVVFLNITSFRNCPMADAPMLQVLEKAAQTVFVPLTVGGG 324
Query: 1153 IRDFTDATGRYYSSLEVAAEYFRSGADKISIGSDAVYAAEEFIKSGVK-TGKSSLEQISR 1329
IRD +D G ++ ++EVA YFRSGADK+SIGSDAVYAAE++ ++G K +GK+++E IS+
Sbjct: 325 IRDVSDPDGTFHPAVEVAGIYFRSGADKVSIGSDAVYAAEKYYENGKKLSGKTAIETISK 384
Query: 1330 VYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAWYQCTVSGGREGRPIGAY 1509
YGNQAVV+S+DP+R YV PED + V++ + GPNGE Y WYQCTV GGRE R I
Sbjct: 385 AYGNQAVVISVDPKRQYVKVPEDTKHHVVKTSRLGPNGEAYCWYQCTVKGGREYRDIDVV 444
Query: 1510 ELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGTPEHFSEVF 1689
EL +A E +GAGE+LLNC+D DG G+D +LV+L+ + V IPVIASSGAG P+HF EVF
Sbjct: 445 ELTRACEAMGAGEVLLNCMDQDGSNAGYDIELVRLVKNSVNIPVIASSGAGIPQHFEEVF 504
Query: 1690 ETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVR 1797
+ T+ AALAAGIFHR+ I+ VKE+L + VR
Sbjct: 505 KETDCDAALAAGIFHRQTCRIEDVKEYLAIHDVLVR 540
>sp|P33734|HIS5_YEAST Imidazole glycerol phosphate synthase hisHF
OS=Saccharomyces cerevisiae GN=HIS7 PE=1 SV=2
Length = 552
Score = 396 bits (1017), Expect = 3e-109
Identities = 195/316 (61%), Positives = 237/316 (75%), Gaps = 1/316 (0%)
Frame = +1
Query: 862 LAKRVIACLDVRTNDKGDLVVTKGDQYDVREQSNENEVRNLGKPVDLAGQYYKDGADEIS 1041
L +R+IACLDVRTND+GDLVVTKGDQYDVRE+S+ VRNLGKPV LA +YY+ GADE++
Sbjct: 236 LTRRIIACLDVRTNDQGDLVVTKGDQYDVREKSDGKGVRNLGKPVQLAQKYYQQGADEVT 295
Query: 1042 FLNITGFRDFPLGDLPMIRVLRYTSENVFVPLTVGGGIRDFTDATGRYYSSLEVAAEYFR 1221
FLNIT FRD PL D PM+ VL+ ++ VFVPLTVGGGI+D D G +LEVA+ YFR
Sbjct: 296 FLNITSFRDCPLKDTPMLEVLKQAAKTVFVPLTVGGGIKDIVDVDGTKIPALEVASLYFR 355
Query: 1222 SGADKISIGSDAVYAAEEFIKSGVK-TGKSSLEQISRVYGNQAVVVSIDPRRVYVNHPED 1398
SGADK+SIG+DAVYAAE++ + G + G S +E IS+ YG QAVV+S+DP+RVYVN D
Sbjct: 356 SGADKVSIGTDAVYAAEKYYELGNRGDGTSPIETISKAYGAQAVVISVDPKRVYVNSQAD 415
Query: 1399 VPYKVIRVTNPGPNGEEYAWYQCTVSGGREGRPIGAYELAKAVEELGAGEILLNCIDCDG 1578
KV PGPNGE+Y WYQCT+ GGRE R +G +EL +A E LGAGEILLNCID DG
Sbjct: 416 TKNKVFETEYPGPNGEKYCWYQCTIKGGRESRDLGVWELTRACEALGAGEILLNCIDKDG 475
Query: 1579 QGKGFDTDLVKLISDLVGIPVIASSGAGTPEHFSEVFETTNASAALAAGIFHRKEVPIQS 1758
G+D +L++ + D V IPVIASSGAG PEHF E F T A A L AG+FHR E +
Sbjct: 476 SNSGYDLELIEHVKDAVKIPVIASSGAGVPEHFEEAFLKTRADACLGAGMFHRGEFTVND 535
Query: 1759 VKEHLLEKSIEVRM*E 1806
VKE+LLE ++VRM E
Sbjct: 536 VKEYLLEHGLKVRMDE 551
>sp|Q92E86|HIS5_LISIN Imidazole glycerol phosphate synthase subunit hisH
OS=Listeria innocua GN=hisH PE=3 SV=1
Length = 208
Score = 167 bits (422), Expect = 3e-040
Identities = 83/199 (41%), Positives = 120/199 (60%), Gaps = 3/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++ ++DY GN +SI AL +G K +IL AD +I PGVGAF AM L + G
Sbjct: 1 MIVIIDYDTGNTKSISKALDFIGLQNKISSNHAEILQADGVILPGVGAFPEAMQELGRRG 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ L E+ +P LG+CLG+QLL +SS+E+ KGLG+IPG V + G VPH+G
Sbjct: 61 LDVTLKEMAESGKPMLGVCLGMQLLLESSDEHLFTKGLGLIPGHVEKLPDEPGFAVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WN L++ + + +G +VY+VHSY A +E +I +T Y S I +GN++
Sbjct: 121 WNQLEIKRSTPLTKKLGGEYVYYVHSYYANCPNE---YIIATSGYSVEVPSMINKGNIYG 177
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKSG++GL +L+ F
Sbjct: 178 AQFHPEKSGQIGLEILKGF 196
>sp|Q7ULP3|HIS5_RHOBA Imidazole glycerol phosphate synthase subunit hisH
OS=Rhodopirellula baltica GN=hisH PE=3 SV=1
Length = 205
Score = 163 bits (411), Expect = 6e-039
Identities = 82/199 (41%), Positives = 121/199 (60%), Gaps = 2/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++T++DY GN+RS++ A+ G + I A+RLI PGVGAF A+ + +
Sbjct: 1 MITIVDYQMGNLRSVQKAVERSGVEAEITSDASQIAAAERLILPGVGAFGDAIGEIRRRD 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ + + +I + +PFLGICLGLQ+LF+ E G +GLGV+ G V F+ A +VPH+G
Sbjct: 61 LEKPIKDFIASGKPFLGICLGLQMLFEQGFEGGTHEGLGVLGGDVVAFELPAEFKVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WNA+ V + L H YFVHSY P+ + ++ TC YG F +++RRGN+ A
Sbjct: 121 WNAVDVKDAGADLGIQSGTHFYFVHSYFVRPADPSV--VALTCDYGGEFCAAVRRGNLMA 178
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKS GL +++RF
Sbjct: 179 TQFHPEKSQGDGLRLMQRF 197
>sp|A8AY26|HIS5_STRGC Imidazole glycerol phosphate synthase subunit hisH
OS=Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 /
V288) GN=hisH PE=3 SV=1
Length = 207
Score = 162 bits (409), Expect = 1e-038
Identities = 84/199 (42%), Positives = 117/199 (58%), Gaps = 3/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++ ++ Y AGN ++ AL +G + + P +IL AD LI PGVGAF AM L K G
Sbjct: 1 MMIVIGYDAGNTANVLRALAQVGVAARLSADPQEILAADGLILPGVGAFPAAMQELEKRG 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ + + + +P LGICLG+QLL +S ENG GLG+IPG R AG+ VPH+G
Sbjct: 61 LISVIQQAVADGKPLLGICLGMQLLLESGLENGQNSGLGLIPGVCRRIPDQAGLPVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WN LQ+ S + + + VYFVHSY + ++++ T YG + I RG+V
Sbjct: 121 WNDLQLQQSSALTAGLDGQSVYFVHSYY---TDVPEEYLDVTADYGRPIPAMIHRGSVFG 177
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKSG VGL +L +F
Sbjct: 178 CQFHPEKSGAVGLGILEKF 196
>sp|A3CNT2|HIS5_STRSV Imidazole glycerol phosphate synthase subunit hisH
OS=Streptococcus sanguinis (strain SK36) GN=hisH PE=3 SV=1
Length = 207
Score = 160 bits (403), Expect = 5e-038
Identities = 83/199 (41%), Positives = 116/199 (58%), Gaps = 3/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++ ++DY AGN ++ AL + + P +IL AD LI PGVGAF AM L + G
Sbjct: 1 MMIVIDYDAGNTANVLRALAQVRVEARLSADPQEILAADGLILPGVGAFPTAMQELERRG 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ + + + +P LGICLG+QLL +S ENG GLG+IPG R AG+ VPH+G
Sbjct: 61 LVSVIQQAVADGKPLLGICLGMQLLLESGLENGQSSGLGLIPGVCRRIPDQAGLPVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WN LQ+ S + + + VYFVHSY + ++++ T YG + I RG+V
Sbjct: 121 WNDLQMQQSSALTASLEGQSVYFVHSYY---TDVPEEYLDVTADYGLPIPAMIHRGSVFG 177
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKSG VGL +L +F
Sbjct: 178 CQFHPEKSGAVGLGILEKF 196
>sp|C1L0J4|HIS5_LISMC Imidazole glycerol phosphate synthase subunit hisH
OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=hisH PE=3
SV=1
Length = 208
Score = 155 bits (390), Expect = 2e-036
Identities = 77/199 (38%), Positives = 114/199 (57%), Gaps = 3/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++ ++DY GN +SI AL +G K +I AD +I PGVGA+ AM L + G
Sbjct: 1 MIVIIDYDTGNTKSISKALDFIGLQNKISSDKTEIAQADGVILPGVGAYPEAMQELTRRG 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ + L +P LG+CLG+QLL +SS E+ KGLG+IPG V + VPH+G
Sbjct: 61 LDKTLKEIATAGKPILGVCLGMQLLLESSNEHSYTKGLGLIPGHVEMLPDESEFAVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WN LQ+ + + ++ +VY+VHSY A + + +I +T Y I GN++
Sbjct: 121 WNQLQIKRTTPLTQNIAGEYVYYVHSYYA---NCPEAYIIATSGYSIDIPGMINNGNIYG 177
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKSG++GL +L+ F
Sbjct: 178 AQFHPEKSGQIGLEILKGF 196
>sp|Q722Y5|HIS5_LISMF Imidazole glycerol phosphate synthase subunit hisH
OS=Listeria monocytogenes serotype 4b (strain F2365) GN=hisH PE=3 SV=1
Length = 208
Score = 155 bits (390), Expect = 2e-036
Identities = 77/199 (38%), Positives = 114/199 (57%), Gaps = 3/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++ ++DY GN +SI AL +G K +I AD +I PGVGA+ AM L + G
Sbjct: 1 MIVIIDYDTGNTKSISKALDFIGLQNKISSDKTEIAQADGVILPGVGAYPEAMQELTRRG 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ + L +P LG+CLG+QLL +SS E+ KGLG+IPG V + VPH+G
Sbjct: 61 LDKTLKEIATAGKPILGVCLGMQLLLESSNEHSYTKGLGLIPGHVEMLPDESEFAVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WN LQ+ + + ++ +VY+VHSY A + + +I +T Y I GN++
Sbjct: 121 WNQLQIKRTTPLTQNIAGEYVYYVHSYYA---NCPEAYIIATSGYSIDIPGMINNGNIYG 177
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKSG++GL +L+ F
Sbjct: 178 AQFHPEKSGQIGLEILKGF 196
>sp|Q8Y9G3|HIS5_LISMO Imidazole glycerol phosphate synthase subunit hisH
OS=Listeria monocytogenes GN=hisH PE=3 SV=1
Length = 208
Score = 153 bits (385), Expect = 6e-036
Identities = 76/199 (38%), Positives = 114/199 (57%), Gaps = 3/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++ ++DY GN +SI AL +G K +I AD +I PGVGA+ AM L + G
Sbjct: 1 MIVIIDYDTGNTKSISKALDFIGLQNKISSDATEISQADGVILPGVGAYPEAMKELTRRG 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ + L +P LG+CLG+QLL +SS E+ GLG+IPG V + VPH+G
Sbjct: 61 LNKTLKEIAAGGKPILGVCLGMQLLLESSNEHSFTNGLGLIPGHVEKLPEDPEFAVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WN LQ+ + + + +VY+VHSY A + +++I +T Y I +GN++
Sbjct: 121 WNQLQIKRATPLTKQLDGEYVYYVHSYYA---NCPEEYIIATSGYSIEVPGMINKGNIYG 177
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKSG++GL +L+ F
Sbjct: 178 AQFHPEKSGQIGLEILKGF 196
>sp|B8DA60|HIS5_LISMH Imidazole glycerol phosphate synthase subunit hisH
OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=hisH PE=3 SV=1
Length = 208
Score = 152 bits (382), Expect = 1e-035
Identities = 76/199 (38%), Positives = 113/199 (56%), Gaps = 3/199 (1%)
Frame = +1
Query: 211 VVTLLDYGAGNVRSIRNALRHLGFSIKDVKTPGDILNADRLIFPGVGAFAPAMDVLNKTG 390
++ ++DY GN +SI AL +G K +I AD +I PGVGA+ AM L + G
Sbjct: 1 MIVIIDYDTGNTKSISKALDFIGLQNKISSDATEISQADGVILPGVGAYPEAMKELTRRG 60
Query: 391 MGEALCTYIENDRPFLGICLGLQLLFDSSEENGPVKGLGVIPGTVGRFDSSAGIRVPHIG 570
+ + L +P LG+CLG+QLL +SS E+ GLG+IPG V + VPH+G
Sbjct: 61 LDKTLKEIAATGKPILGVCLGMQLLLESSNEHSFTSGLGLIPGHVEKLPEEPEFAVPHMG 120
Query: 571 WNALQVGNDSEILDDVGNRHVYFVHSYRAIPSSENKDWISSTCHYGESFISSIRRGNVHA 750
WN LQ+ + + + +VY+VHSY A + +++I +T Y I GN++
Sbjct: 121 WNQLQIKRATPLTKQLDGEYVYYVHSYYA---NCPEEYIIATSGYSIEVPGMINNGNIYG 177
Query: 751 VQFHPEKSGEVGLSVLRRF 807
QFHPEKSG++GL +L+ F
Sbjct: 178 AQFHPEKSGQIGLEILKGF 196
>sp|A5UMZ1|HIS6_METS3 Imidazole glycerol phosphate synthase subunit hisF
OS=Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861)
GN=hisF PE=3 SV=1
Length = 274
Score = 146 bits (366), Expect = 1e-033
Identities = 77/163 (47%), Positives = 104/163 (63%), Gaps = 5/163 (3%)
Frame = +1
Query: 1312 LEQISRVYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAWYQCTVSGGREG 1491
L + S+V G+QAVVV ID +R YV++P D P K + T+ G Y W+ C++ GGRE
Sbjct: 117 LTEASKVVGSQAVVVGIDAKRRYVDNPSDAPDKNVVETDEG-----YCWFDCSIYGGREF 171
Query: 1492 RPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGTPE 1671
+ A E A +ELGAGEILL +D DG +G+D L K I+D + IPVIAS G G P
Sbjct: 172 TGMDAIEWAVKCQELGAGEILLTSMDGDGTKEGYDIALNKAINDAIDIPVIASGGGGNPA 231
Query: 1672 HFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVRM 1800
H +VF+ T+ SAALAA IFH + I VK++L E ++ VR+
Sbjct: 232 HILDVFQKTDVSAALAASIFHFNQYSINDVKQYLKENNVPVRL 274
>sp|Q2NI84|HIS6_METST Imidazole glycerol phosphate synthase subunit hisF
OS=Methanosphaera stadtmanae (strain DSM 3091) GN=hisF PE=3 SV=1
Length = 274
Score = 133 bits (334), Expect = 5e-030
Identities = 75/165 (45%), Positives = 96/165 (58%), Gaps = 5/165 (3%)
Frame = +1
Query: 1306 SSLEQISRVYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAWYQCTVSGGR 1485
S + + S G+QA V+ ID +R YV +P + I TN G Y W+ C++ GGR
Sbjct: 115 SLINRASEHVGSQACVIGIDAKRRYVENPSESDEHYIVETNDG-----YCWFDCSIYGGR 169
Query: 1486 EGRPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGT 1665
E I A + A EE GAGEILL +D DG G+D +L K IS+ V IPVIAS G G
Sbjct: 170 EFTGIDAVKWAIECEERGAGEILLTSMDRDGTKIGYDLELTKTISENVSIPVIASGGVGN 229
Query: 1666 PEHFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVRM 1800
PEH + F A AALAA IFH E PI VK +L +K+I +R+
Sbjct: 230 PEHIYDSFSKGKADAALAASIFHFDEYPIPQVKNYLKDKNIPIRI 274
>sp|O27398|HIS6_METTH Imidazole glycerol phosphate synthase subunit hisF
OS=Methanobacterium thermoautotrophicum GN=hisF PE=3 SV=2
Length = 274
Score = 129 bits (323), Expect = 9e-029
Identities = 67/163 (41%), Positives = 97/163 (59%), Gaps = 5/163 (3%)
Frame = +1
Query: 1312 LEQISRVYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAWYQCTVSGGREG 1491
+ + S + G+QA VV+ID +R Y+ +P + + I + G Y WY+C++ GGRE
Sbjct: 117 INEASDLVGSQACVVAIDAKRRYIENPRESDERFIIEVDDG-----YCWYECSIYGGREF 171
Query: 1492 RPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGTPE 1671
I A + A ++ GAGEILL +D DG G+D L + +S+ + IPVIAS G G PE
Sbjct: 172 TGIDAVKWAMECQDRGAGEILLTSMDRDGTKMGYDIPLTRTMSENLDIPVIASGGVGEPE 231
Query: 1672 HFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVRM 1800
H E F A AALAA IFH E P+ +VKE+L + + +R+
Sbjct: 232 HIYEAFTDGKADAALAASIFHFNEYPVPAVKEYLRSRGVPIRL 274
>sp|Q8TYW8|HIS6_METKA Imidazole glycerol phosphate synthase subunit hisF
OS=Methanopyrus kandleri GN=hisF PE=3 SV=1
Length = 272
Score = 125 bits (312), Expect = 2e-027
Identities = 71/162 (43%), Positives = 98/162 (60%), Gaps = 5/162 (3%)
Frame = +1
Query: 1312 LEQISRVYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAWYQCTVSGGREG 1491
+ + + ++G+Q VVV+ID +R + + I + G EY W++ V GGRE
Sbjct: 114 ISEAADIFGSQCVVVAIDAKREPLKPEHEHVADHIFSNDDG----EY-WFRVYVRGGREP 168
Query: 1492 RPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGTPE 1671
+ A AK VEELGAGEILL ID DG +G+D +L + + + V IPVIAS G G P+
Sbjct: 169 VDLDAITWAKRVEELGAGEILLTSIDADGTQEGYDIELTREVCNAVSIPVIASGGCGHPK 228
Query: 1672 HFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVR 1797
H EVF+ +A AALAA IFH + I+ VKEHL E+ + VR
Sbjct: 229 HMVEVFKEADADAALAASIFHYGKFTIEEVKEHLAERGVRVR 270
>sp|Q0W358|HIS6_UNCMA Imidazole glycerol phosphate synthase subunit hisF
OS=Uncultured methanogenic archaeon RC-I GN=hisF PE=3 SV=1
Length = 273
Score = 119 bits (298), Expect = 7e-026
Identities = 67/162 (41%), Positives = 94/162 (58%), Gaps = 6/162 (3%)
Frame = +1
Query: 1312 LEQISRVYGNQAVVVSIDPRRVYVNHPEDVPYKVIRVTNPGPNGEEYAWYQCTVSGGREG 1491
+ + S ++G+Q +V +ID R N + ++R + P AWY+ + GGR+
Sbjct: 117 IRKASDIFGSQCIVTAIDCRS-NTNIDDPNARNIVRRRDGTP-----AWYEVVIYGGRKA 170
Query: 1492 RPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGTPE 1671
I A E AK +EELG+GEI+L +D DG G+D + K I + V IPVIAS GAGT E
Sbjct: 171 TGIDAIEWAKTIEELGSGEIMLTSMDADGTKDGYDLYITKAIGEAVRIPVIASGGAGTIE 230
Query: 1672 HFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVR 1797
H + F+ NA AALAA IFH E I K++L ++ I VR
Sbjct: 231 HMYDAFKIANADAALAASIFHFGEYTIGQAKDYLRQRGIPVR 272
>sp|Q8R885|HIS6_THETN Imidazole glycerol phosphate synthase subunit hisF
OS=Thermoanaerobacter tengcongensis GN=hisF PE=3 SV=1
Length = 253
Score = 116 bits (290), Expect = 6e-025
Identities = 83/214 (38%), Positives = 111/214 (51%), Gaps = 22/214 (10%)
Frame = +1
Query: 1195 LEVAAEYFRSGADKISIGSDAVYAAEE--FIKSGVKTGKSSLEQISRVYGNQAVVVSIDP 1368
L++ A Y +K I D V E FI V G S ++ I V A VSI+
Sbjct: 50 LDITASY-----EKRKIMIDVVKRTSEKVFIPLTVGGGISDIDDIREVLKAGADKVSINT 104
Query: 1369 RRVYVNHPEDVPYKVIRV----------TNPGPNGEEYAWYQCTVSGGREGRPIGAYELA 1518
+ V P + +R P+G Y Y ++GGR + A E A
Sbjct: 105 QA--VKQPTLIRQAALRFGSQCVVVAIDAKKRPDGTGYNVY---INGGRINTGLDAVEWA 159
Query: 1519 KAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVGIPVIASSGAGTPEHFSEVFETT 1698
K V++LGAGEILL +D DG G+D +L +LIS+ V IPVIAS GAG PEHF EVF
Sbjct: 160 KKVKDLGAGEILLTSMDKDGTKDGYDIELTRLISEAVSIPVIASGGAGKPEHFKEVFTQG 219
Query: 1699 NASAALAAGIFHRKEVPIQSVKEHLLEKSIEVRM 1800
A AALAA +FH E+ I+ +K +L ++ I VR+
Sbjct: 220 KADAALAASVFHYGELDIKELKRYLKDEGIPVRL 253
>sp|Q3INY2|HIS6_NATPD Imidazole glycerol phosphate synthase subunit hisF
OS=Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) GN=hisF PE=3
SV=1
Length = 271
Score = 116 bits (289), Expect = 8e-025
Identities = 58/118 (49%), Positives = 73/118 (61%)
Frame = +1
Query: 1447 EYAWYQCTVSGGREGRPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDL 1626
E W++CT+ GGREG E A + GAGE+ +N ID DG G+D L K + D
Sbjct: 154 ESCWFECTIKGGREGTGTDVVEWAGEAADRGAGELFVNSIDADGTKDGYDIPLTKAVCDN 213
Query: 1627 VGIPVIASSGAGTPEHFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVRM 1800
V PVIASSG G+PEH +EVFE +A AALAA IFH +E I+ K L E+ I VR+
Sbjct: 214 VPTPVIASSGCGSPEHMAEVFEDADADAALAASIFHFEEYSIEETKRSLDEQGIPVRL 271
>sp|O29439|HIS6_ARCFU Imidazole glycerol phosphate synthase subunit hisF
OS=Archaeoglobus fulgidus GN=hisF PE=3 SV=1
Length = 271
Score = 115 bits (287), Expect = 1e-024
Identities = 60/116 (51%), Positives = 77/116 (66%)
Frame = +1
Query: 1453 AWYQCTVSGGREGRPIGAYELAKAVEELGAGEILLNCIDCDGQGKGFDTDLVKLISDLVG 1632
AWY+ + GGR+ I A AK VEELGAGEILL ++ DG GFD + + IS+ V
Sbjct: 156 AWYEVVIYGGRKPVGIDAVWWAKRVEELGAGEILLTSMNRDGTKDGFDIPITRKISEEVN 215
Query: 1633 IPVIASSGAGTPEHFSEVFETTNASAALAAGIFHRKEVPIQSVKEHLLEKSIEVRM 1800
IPVIAS GAGT EHF E F A A LAA IFH +E+ I+ +KE+L E+ ++VR+
Sbjct: 216 IPVIASGGAGTKEHFYEGFVEGKADACLAASIFHYREIGIREIKEYLAERGVQVRL 271
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,436,365,428
Number of Sequences: 518415
Number of Extensions: 75436365428
Number of Successful Extensions: 513409628
Number of sequences better than 0.0: 0
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