BLASTX 7.6.2
Query= UN18507 /QuerySize=1344
(1343 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O64765|UAP1_ARATH Probable UDP-N-acetylglucosamine pyrophosph... 604 5e-172
sp|Q28CH3|UAP1L_XENTR UDP-N-acetylhexosamine pyrophosphorylase-l... 253 3e-066
sp|O74933|UAP1_CANAL UDP-N-acetylglucosamine pyrophosphorylase O... 241 1e-062
sp|Q7ZWD4|UAP1L_DANRE UDP-N-acetylhexosamine pyrophosphorylase-l... 239 5e-062
sp|Q3KQV9|UAP1L_HUMAN UDP-N-acetylhexosamine pyrophosphorylase-l... 239 5e-062
sp|Q91YN5|UAP1_MOUSE UDP-N-acetylhexosamine pyrophosphorylase OS... 239 5e-062
sp|P43123|UAP1_YEAST UDP-N-acetylglucosamine pyrophosphorylase O... 238 7e-062
sp|Q54GN5|UAP1_DICDI Probable UDP-N-acetylglucosamine pyrophosph... 233 4e-060
sp|Q3TW96|UAP1L_MOUSE UDP-N-acetylhexosamine pyrophosphorylase-l... 230 3e-059
sp|Q16222|UAP1_HUMAN UDP-N-acetylhexosamine pyrophosphorylase OS... 228 7e-059
sp|O94617|UAP1_SCHPO Probable UDP-N-acetylglucosamine pyrophosph... 201 9e-051
sp|Q4L846|URTF_STAHJ Probable uridylyltransferase SH0870 OS=Stap... 165 9e-040
sp|Q2FEW1|URTF_STAA3 Probable uridylyltransferase SAUSA300_2130 ... 122 9e-027
sp|Q2FW81|URTF_STAA8 Probable uridylyltransferase SAOUHSC_02423 ... 122 9e-027
sp|Q5HE34|URTF_STAAC Probable uridylyltransferase SACOL2161 OS=S... 122 9e-027
sp|Q99S95|URTF_STAAM Probable uridylyltransferase SAV2171 OS=Sta... 121 2e-026
sp|Q7A4A4|URTF_STAAN Probable uridylyltransferase SA1974 OS=Stap... 121 2e-026
sp|Q6G7E3|URTF_STAAS Probable uridylyltransferase SAS2072 OS=Sta... 121 2e-026
sp|Q7A0A0|URTF_STAAW Probable uridylyltransferase MW2097 OS=Stap... 121 2e-026
sp|Q6GEQ8|URTF_STAAR Probable uridylyltransferase SAR2262 OS=Sta... 120 3e-026
>sp|O64765|UAP1_ARATH Probable UDP-N-acetylglucosamine pyrophosphorylase
OS=Arabidopsis thaliana GN=At2g35020 PE=2 SV=1
Length = 502
Score = 604 bits (1557), Expect = 5e-172
Identities = 306/347 (88%), Positives = 322/347 (92%), Gaps = 5/347 (1%)
Frame = +3
Query: 123 EEPTTEEIEIRTADVTTKTLPPPPPPRTASPHQELVERLKDYGQEDVFALWEELSPEERH 302
+EPTT EIEI T+ V T LPPP PP TASPHQ LVERLKDYGQEDVF+LW+ELSPEER
Sbjct: 2 KEPTT-EIEIETSAVAT-ILPPPLPP-TASPHQALVERLKDYGQEDVFSLWDELSPEERD 58
Query: 303 LLVTEIENLDLPRIDRIIRCSLNSQGLPAAAIEAPPESCVSTVEGRRKEDKEKWWKMGLK 482
LL+ +IENLDLPRIDRIIRCSL+SQGLP AAIE PE+CVSTVE R KED+EKWWKMGLK
Sbjct: 59 LLLRDIENLDLPRIDRIIRCSLHSQGLPVAAIEPVPENCVSTVEERTKEDREKWWKMGLK 118
Query: 483 AIYEGKLGVVLLSGGQGTRLGSSDPKGCFNIGLPSGKSLFQIQAERILCVQRLAAQAM-- 656
AIYEGKLGVVLLSGGQGTRLGSSDPKGC+NIGLPSGKSLFQIQAERILCVQRLA+QAM
Sbjct: 119 AIYEGKLGVVLLSGGQGTRLGSSDPKGCYNIGLPSGKSLFQIQAERILCVQRLASQAMSE 178
Query: 657 AGPTRSVAIQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIME 836
A PTR V IQWYIMTSPFTHEPTQKFF+SHKYFGLEP QVTFFQQGTLPCI+KDGKFIME
Sbjct: 179 ASPTRPVTIQWYIMTSPFTHEPTQKFFKSHKYFGLEPDQVTFFQQGTLPCISKDGKFIME 238
Query: 837 TPFSLAKAPDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDK 1016
TPFSL+KAPDGNGGVY ALK SRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDK
Sbjct: 239 TPFSLSKAPDGNGGVYTALKSSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDK 298
Query: 1017 GAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
AASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELD+SMASA+N
Sbjct: 299 SAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELDQSMASATN 345
>sp|Q28CH3|UAP1L_XENTR UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
OS=Xenopus tropicalis GN=uap1l1 PE=2 SV=1
Length = 511
Score = 253 bits (644), Expect = 3e-066
Identities = 141/316 (44%), Positives = 190/316 (60%), Gaps = 14/316 (4%)
Frame = +3
Query: 234 RLKDYGQEDVFALWEELSPEERHLLVTEIENLDLPRI--------DRIIRCSLNSQGLPA 389
R ++ GQ +F W+ELSP E+ L+ ++E L+ + + +R S Q L
Sbjct: 16 RAEESGQGQLFRFWDELSPAEKEALLEQLEMLEPRELREHCQRAREAYVRESSAPQRLDD 75
Query: 390 AAIEAPPESCVSTVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCF 569
PPE + +V + E+W + G I + K+ V+LL+GGQGTRLG + PKG +
Sbjct: 76 RMQPVPPE-FLGSVRHSGTGELERWEREGFHQIAQNKVAVLLLAGGQGTRLGVTYPKGMY 134
Query: 570 NIGLPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFFESHK 749
++GLPS K+L+QIQAERI +Q+LA++ + + WYIMTS FT PT+KFFE H
Sbjct: 135 SVGLPSAKTLYQIQAERIRRLQQLASERHG---ETCTVPWYIMTSEFTLGPTRKFFEDHA 191
Query: 750 YFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLEDMASR 929
YFGLE V F+Q LP + DG I+E LA APDGNGG+Y AL +R+LEDM R
Sbjct: 192 YFGLERSDVVMFEQRMLPAVGFDGAAILEDKAKLAMAPDGNGGLYRALSDNRILEDMEGR 251
Query: 930 GIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGPLT 1109
GI+YV Y VDN+LV++ADP F+G+ + KGA AKVV K YP E VGV R G
Sbjct: 252 GIQYVHVYCVDNILVKMADPVFIGFCVSKGADCGAKVVEKGYPAEPVGVVCR--VDGVYQ 309
Query: 1110 VVEYTELDESMASASN 1157
VVEY+E+ A N
Sbjct: 310 VVEYSEISPETAEKRN 325
>sp|O74933|UAP1_CANAL UDP-N-acetylglucosamine pyrophosphorylase OS=Candida
albicans GN=UAP1 PE=1 SV=1
Length = 486
Score = 241 bits (614), Expect = 1e-062
Identities = 132/321 (41%), Positives = 198/321 (61%), Gaps = 9/321 (2%)
Frame = +3
Query: 204 TASPHQELVERLKDYGQEDVFALWEELSPEERHLLVTEIENLDLP-----RIDRIIRCSL 368
T Q++++ K Q+ +F ++ L+ +++ + ++ ++ P +++ I+ S
Sbjct: 2 TVKSQQQIIDSFKQANQDQLFQYYDSLTIDQQQEFIDQLSTIEEPAKLISTVEQAIQFS- 60
Query: 369 NSQGLPAAAIEAPPESCVSTVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGS 548
+ + P E ST++ K+ + W ++GLKAI G++ V+L++GGQGTRLGS
Sbjct: 61 QTNSTSRNFTQLPNEQTASTLD-LSKDILQNWTELGLKAIGNGEVAVLLMAGGQGTRLGS 119
Query: 549 SDPKGCFNIGLPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQ 728
S PKGCFNI LPS KSLFQIQAE+IL +++LA Q + T+ I WYIMTS T T+
Sbjct: 120 SAPKGCFNIELPSQKSLFQIQAEKILKIEQLAQQYLKS-TKKPIINWYIMTSGPTRNATE 178
Query: 729 KFFESHKYFGLEPGQVTFFQQGTLPCITKDG-KFIMETPFSLAKAPDGNGGVYAALKYSR 905
FF + YFGL QV FF QGTLPC G K ++E+ S+ ++PDGNGG+Y ALK +
Sbjct: 179 SFFIENNYFGLNSHQVIFFNQGTLPCFNLQGNKILLESKNSICQSPDGNGGLYKALKDNG 238
Query: 906 LLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVR 1085
+L+D+ S+GIK++ Y VDN LV+VADP F+G+ I K A KVVRK E VG+ V
Sbjct: 239 ILDDLNSKGIKHIHMYCVDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANESVGLIVL 298
Query: 1086 RGKGGPLTVVEYTELDESMAS 1148
V+EY+E+ + +A+
Sbjct: 299 DQDNQKPCVIEYSEISQELAN 319
>sp|Q7ZWD4|UAP1L_DANRE UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
OS=Danio rerio GN=uap1l1 PE=2 SV=1
Length = 505
Score = 239 bits (608), Expect = 5e-062
Identities = 134/316 (42%), Positives = 185/316 (58%), Gaps = 12/316 (3%)
Frame = +3
Query: 219 QELVERLKDYGQEDVFALWEELSPEERHLLVTEIENLDLPRIDRIIRCSL-------NSQ 377
+E +L+ GQ V W+ELS EER + EI L + R + ++
Sbjct: 4 EEAKAKLEAAGQTHVLQFWDELSAEERGTFLEEISQLQPDELVEHCREAAASASRHSSAD 63
Query: 378 GLPAAAIEAPPESCVSTVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDP 557
G A ++ P + +V +E +KW GL I + ++ V+LL+GGQGTRLG S P
Sbjct: 64 GRLDARMQPVPPEFIGSVRKSDRETLQKWENEGLLQISQDRVAVLLLAGGQGTRLGVSYP 123
Query: 558 KGCFNIGLPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFF 737
KG +N+GLPSGK+L+QIQAERI VQ LA + WYIMTS FT PT+KFF
Sbjct: 124 KGMYNVGLPSGKTLYQIQAERIQKVQELANVRHG---CRCTVPWYIMTSEFTLGPTEKFF 180
Query: 738 ESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLED 917
+ +KYFGL P V F+Q +P + DGK I+E +A APDGNGG+Y +L +++L D
Sbjct: 181 KDNKYFGLCPSNVVMFEQRMIPAVGFDGKIILEKKNKIAMAPDGNGGLYRSLVDNKILAD 240
Query: 918 MASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKG 1097
M R ++++ Y VDN+LV++ADP F+G+ + GA AKVV KAYP E VGV R
Sbjct: 241 MERRNVEFLHVYCVDNILVKMADPVFIGFCVTNGADCGAKVVEKAYPAEPVGVVCR--VD 298
Query: 1098 GPLTVVEYTELDESMA 1145
G V+EY+E+ A
Sbjct: 299 GVYQVIEYSEIQPETA 314
>sp|Q3KQV9|UAP1L_HUMAN UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
OS=Homo sapiens GN=UAP1L1 PE=2 SV=2
Length = 507
Score = 239 bits (608), Expect = 5e-062
Identities = 134/316 (42%), Positives = 188/316 (59%), Gaps = 12/316 (3%)
Frame = +3
Query: 219 QELVERLKDYGQEDVFALWEELSPEERHLLVTEIENLDLPRIDRIIRCSLNSQGLP---- 386
Q++ RL+ GQE + W EL+PE R L+ E+ L+ + R + + P
Sbjct: 5 QDVRARLQRAGQEHLLRFWAELAPEPRAALLAELALLEPEALREHCRRAAEACARPHGPP 64
Query: 387 ---AAAIEAPPESCVSTVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDP 557
AA + P V E + +W + G + I K+ V+LL+GGQGTRLG + P
Sbjct: 65 PDLAARLRPLPPERVGRASRSDPETRRRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYP 124
Query: 558 KGCFNIGLPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFF 737
KG + +GLPS K+L+Q+QAERI V++LA + TR + WY+MTS FT PT +FF
Sbjct: 125 KGMYRVGLPSRKTLYQLQAERIRRVEQLAGERHG--TR-CTVPWYVMTSEFTLGPTAEFF 181
Query: 738 ESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLED 917
H +F L+P V F+Q LP +T DGK I+E +A APDGNGG+Y AL+ ++LED
Sbjct: 182 REHNFFHLDPANVVMFEQRLLPAVTFDGKVILERKDKVAMAPDGNGGLYCALEDHKILED 241
Query: 918 MASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKG 1097
M RG+++V Y VDN+LVR+ADP F+G+ + +GA AKVV KAYP+E VGV +
Sbjct: 242 MERRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQ--VD 299
Query: 1098 GPLTVVEYTELDESMA 1145
G VVEY+E+ A
Sbjct: 300 GVPQVVEYSEISPETA 315
>sp|Q91YN5|UAP1_MOUSE UDP-N-acetylhexosamine pyrophosphorylase OS=Mus musculus
GN=Uap1 PE=1 SV=1
Length = 522
Score = 239 bits (608), Expect = 5e-062
Identities = 141/325 (43%), Positives = 192/325 (59%), Gaps = 15/325 (4%)
Frame = +3
Query: 222 ELVERLKDYGQEDVFALWEELSPEERHLLVTEIENLDLPRIDRIIRCSL------NSQGL 383
+L +RL GQE + W ELS ++ L E++ ++ ++ R ++ + Q
Sbjct: 5 DLKQRLSQAGQEHLLQFWNELSEAQQVELYMELQAMNFEELNSFFRKAIGEFDRSSHQEK 64
Query: 384 PAAAIEAPPESCVSTVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKG 563
A +E P + + R +E + W GL I + K+ V+LL+GGQGTRLG S PKG
Sbjct: 65 VDARMEPVPRQVLGSAT-RDQEQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVSYPKG 123
Query: 564 CFNIGLPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFFES 743
+++GLPS K+LFQIQAERIL +Q+LA + I WYIMTS T E T++FF
Sbjct: 124 MYDVGLPSHKTLFQIQAERILKLQQLAEKHHG---NKCTIPWYIMTSGRTMESTKEFFTK 180
Query: 744 HKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLEDMA 923
HK+FGL+ V FFQQG LP ++ DGK I+E ++ APDGNGG+Y AL ++EDM
Sbjct: 181 HKFFGLKKENVVFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240
Query: 924 SRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGP 1103
RGI + Y VDN+LV+VADP F+G+ I KGA AKVV K P E VGV R G
Sbjct: 241 QRGICSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCR--VDGV 298
Query: 1104 LTVVEYTELDESMA---SASNLLLF 1169
VVEY+E+ + A S+ LLF
Sbjct: 299 YQVVEYSEISLATAQRRSSDGRLLF 323
>sp|P43123|UAP1_YEAST UDP-N-acetylglucosamine pyrophosphorylase OS=Saccharomyces
cerevisiae GN=UAP1 PE=1 SV=1
Length = 477
Score = 238 bits (607), Expect = 7e-062
Identities = 133/314 (42%), Positives = 191/314 (60%), Gaps = 21/314 (6%)
Frame = +3
Query: 249 GQEDVFALWEELSPEERHLLVTEIENLDLPR--------IDRIIRCSL--NSQGLPAAAI 398
GQ +F WE LS +++ L++ +E + R I+ SL +S+
Sbjct: 12 GQSQLFHNWESLSRKDQEELLSNLEQISSKRSPAKLLEDCQNAIKFSLANSSKDTGVEIS 71
Query: 399 EAPPESCVSTVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCFNIG 578
PP S S + +KE+ ++W++GL+AI +G++ V+L++GGQGTRLGSS PKGC++IG
Sbjct: 72 PLPPTSYESLIGNSKKEN--EYWRLGLEAIGKGEVAVILMAGGQGTRLGSSQPKGCYDIG 129
Query: 579 LPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFFESHKYFG 758
LPS KSLFQIQAE+++ +Q + + V I WYIMTS T T+ +F+ H YFG
Sbjct: 130 LPSKKSLFQIQAEKLIRLQDMVKD------KKVEIPWYIMTSGPTRAATEAYFQEHNYFG 183
Query: 759 LEPGQVTFFQQGTLPCITKDGK-FIMETPFSLAKAPDGNGGVYAALKYSRLLEDMASRGI 935
L Q+TFF QGTLP GK F+M+ P +L+++PDGNGG+Y A+K ++L ED RGI
Sbjct: 184 LNKEQITFFNQGTLPAFDLTGKHFLMKDPVNLSQSPDGNGGLYRAIKENKLNEDFDRRGI 243
Query: 936 KYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVV 1115
K+V Y VDNVL ++ADP F+G+ I G A K VRK E VG+ K V+
Sbjct: 244 KHVYMYCVDNVLSKIADPVFIGFAIKHGFELATKAVRKRDAHESVGLIAT--KNEKPCVI 301
Query: 1116 EYTELDESMASASN 1157
EY+E+ +A A +
Sbjct: 302 EYSEISNELAEAKD 315
>sp|Q54GN5|UAP1_DICDI Probable UDP-N-acetylglucosamine pyrophosphorylase
OS=Dictyostelium discoideum GN=uap1 PE=3 SV=1
Length = 487
Score = 233 bits (592), Expect = 4e-060
Identities = 129/301 (42%), Positives = 191/301 (63%), Gaps = 5/301 (1%)
Frame = +3
Query: 243 DYGQEDVFALWEELSPEERHLLVTEIENLDLPRIDRIIRCSLNSQGLPAAAIEAPPESCV 422
+ GQ VF +++LS EE+ +I +++ +++ + L ++ ++ V
Sbjct: 15 EQGQGHVFNWFDKLSNEEKLNFENDIRKINVKEVNKDYKNVLLNKD-EQKIMKYEHFENV 73
Query: 423 STVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCFNIGLPSGKSLF 602
T+ +++DK+KW +G + I +G++ V+LL+GGQ TRLG++ PKG +++GLPS KSLF
Sbjct: 74 MTLNKIKEQDKKKWEDIGYELISKGEVAVLLLAGGQATRLGTTFPKGFYDVGLPSKKSLF 133
Query: 603 QIQAERILCVQRLAAQAMAG--PTRSVAIQWYIMTSPFTHEPTQKFFESHKYFGLEPGQV 776
Q+QAERI +Q+L ++ G S IQWYIMTS TH T KFFE+ YFGL+
Sbjct: 134 QLQAERIYRLQQLVSERYNGSYDQDSKPIQWYIMTSEATHSETIKFFENKNYFGLKKSAF 193
Query: 777 TFFQQGTLPCIT-KDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLEDMASRGIKYVDCY 953
FF Q +PCIT +DGK I E+ L+ +P+GNGG++ AL S ++DM +GIKYV Y
Sbjct: 194 FFFSQAMIPCITPEDGKIISESGSKLSLSPNGNGGLFKALSTSGAIDDMRKKGIKYVTQY 253
Query: 954 GVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELD 1133
VDN+L+ +ADP F+GY D+ A AKVV K+ P+E VGV G G P V+EY+E+D
Sbjct: 254 CVDNILINMADPVFVGYMHDQSADCGAKVVSKSDPKEPVGVMALNGDGKPF-VLEYSEID 312
Query: 1134 E 1136
E
Sbjct: 313 E 313
>sp|Q3TW96|UAP1L_MOUSE UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
OS=Mus musculus GN=Uap1l1 PE=2 SV=1
Length = 507
Score = 230 bits (584), Expect = 3e-059
Identities = 132/311 (42%), Positives = 189/311 (60%), Gaps = 12/311 (3%)
Frame = +3
Query: 234 RLKDYGQEDVFALWEELSPEERHLLVTEIENLDLPRI----DRIIRCSLNSQG-LP--AA 392
+L+ GQ+ + + +L+PE R L+ E+ +L+ + R + G LP AA
Sbjct: 10 QLQRAGQDHLLRFYADLAPEARAALLAELASLEADALREHCQRAAAAGALAPGPLPDLAA 69
Query: 393 AIEAPPESCVSTVEGRRKEDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCFN 572
++ P V + +E + +W + G + I K+ V+LL+GGQGTRLG + PKG +
Sbjct: 70 RLQPLPPERVGSAIRCDQETRLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQ 129
Query: 573 IGLPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFFESHKY 752
+GLPS K+L+Q+QAERI VQ+LA Q + WYIMTS FT PT KFF+ H +
Sbjct: 130 VGLPSQKTLYQLQAERIRRVQQLADQRQG---THCTVPWYIMTSEFTLGPTIKFFKEHDF 186
Query: 753 FGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLEDMASRG 932
F L+P V F+Q LP +T +GK I+E +A APDGNGG+Y AL ++LEDM RG
Sbjct: 187 FHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRG 246
Query: 933 IKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGPLTV 1112
+++V Y VDN+LVR+ADP F+G+ + +GA AKVV KAYP+E VGV + G V
Sbjct: 247 VEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQ--VDGVPQV 304
Query: 1113 VEYTELDESMA 1145
VEY+E+ +A
Sbjct: 305 VEYSEISPEIA 315
>sp|Q16222|UAP1_HUMAN UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens
GN=UAP1 PE=1 SV=3
Length = 522
Score = 228 bits (581), Expect = 7e-059
Identities = 136/319 (42%), Positives = 187/319 (58%), Gaps = 13/319 (4%)
Frame = +3
Query: 237 LKDYGQEDVFALWEELSPEERHLLVTEIENLDLPRIDRIIRCSLN--SQGLPAAAIEAPP 410
L GQE + W EL ++ L E++ ++ ++ + ++ +Q ++A
Sbjct: 10 LSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDARM 69
Query: 411 ESCVSTVEGRRKEDKEK---WWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCFNIGL 581
E V G D+++ W GL I + K+ V+LL+GGQGTRLG + PKG +++GL
Sbjct: 70 EPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGL 129
Query: 582 PSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFFESHKYFGL 761
PS K+LFQIQAERIL +Q++A + I WYIMTS T E T++FF HKYFGL
Sbjct: 130 PSRKTLFQIQAERILKLQQVAEKYYG---NKCIIPWYIMTSGRTMESTKEFFTKHKYFGL 186
Query: 762 EPGQVTFFQQGTLPCITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLEDMASRGIKY 941
+ V FFQQG LP ++ DGK I+E ++ APDGNGG+Y AL ++EDM RGI
Sbjct: 187 KKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWS 246
Query: 942 VDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEY 1121
+ Y VDN+LV+VADP F+G+ I KGA AKVV K P E VGV R G VVEY
Sbjct: 247 IHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCR--VDGVYQVVEY 304
Query: 1122 TELDESMA---SASNLLLF 1169
+E+ + A S+ LLF
Sbjct: 305 SEISLATAQKRSSDGRLLF 323
>sp|O94617|UAP1_SCHPO Probable UDP-N-acetylglucosamine pyrophosphorylase
OS=Schizosaccharomyces pombe GN=SPBC1289.08 PE=1 SV=1
Length = 475
Score = 201 bits (511), Expect = 9e-051
Identities = 120/308 (38%), Positives = 169/308 (54%), Gaps = 19/308 (6%)
Frame = +3
Query: 306 LVTEIENLDLPRIDRIIR--CSLNSQGLPAAAIEAPPESCVSTVEGRRKEDKEKWWKMGL 479
L+ +++ LDL + R + + + + E P S V T + WW+ GL
Sbjct: 38 LLNQVQQLDLRSLWLKYRNAKATSQENRKLSPSEVGPLSIVDTSD-------SSWWRTGL 90
Query: 480 KAIYEGKLGVVLLSGGQGTRLGSSDPKGCFNIGLPSGKSLFQIQAERILCVQRLAAQAMA 659
+ I G + ++L+GGQGTRLG + PKGCF +GLP+ S+F++QA++I LA A
Sbjct: 91 REIARGHVAALVLAGGQGTRLGFAGPKGCFRLGLPNNPSIFELQAQKIKKSLALARAAFP 150
Query: 660 GPTRSVAIQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMET 839
S++I WYIM S T E T FF+ + +FG++ V FFQQG LPC+ G+ + E+
Sbjct: 151 DQEASISIPWYIMVSECTSEETISFFKENDFFGIDKKDVFFFQQGVLPCLDISGRVLFES 210
Query: 840 PFSLAKAPDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKG 1019
SLA AP+GNGG+Y AL S L DM RGI ++ Y VDNVLV DP F+G K
Sbjct: 211 DSSLAWAPNGNGGIYEALLSSGALNDMNRRGILHITAYSVDNVLVLPVDPVFIGMATTKK 270
Query: 1020 AASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASAS-------NLLLFLLS 1178
A K V K P EKVG+ V VVEY+E+ + A+ +LLL +
Sbjct: 271 LEVATKTVEKIDPAEKVGLLV--SSHNHPCVVEYSEISDEACKATENVDGHKHLLLRAAN 328
Query: 1179 LAI-FFSF 1199
+A +FSF
Sbjct: 329 IAYHYFSF 336
>sp|Q4L846|URTF_STAHJ Probable uridylyltransferase SH0870 OS=Staphylococcus
haemolyticus (strain JCSC1435) GN=SH0870 PE=3 SV=1
Length = 395
Score = 165 bits (416), Expect = 9e-040
Identities = 101/295 (34%), Positives = 162/295 (54%), Gaps = 28/295 (9%)
Frame = +3
Query: 282 LSPEERHLLVTEIENLDLPRIDRIIR-CSLNSQGLPAAAIEAPPESCVSTVEGRRK---- 446
+S E+ L +++ LDL I ++ + +N Q + S VS V+ +RK
Sbjct: 22 MSSNEKEKLESKVNELDLESIQQLFQDLYVNRQSISDV-------SSVSEVKYQRKTELT 74
Query: 447 -EDKEKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCFNIGLPSGKSLFQIQAERI 623
++ K+ + G++AI G+ V+L++GGQGTRLG PKG F I G SLF++QA ++
Sbjct: 75 DQEGAKYEQKGIEAIRNGEFAVLLMAGGQGTRLGYKGPKGSFEI---KGVSLFELQARQL 131
Query: 624 LCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLP 803
L +++ I WYIMTS HE T +FE H YFG P V FF+Q +
Sbjct: 132 LKLKKETGH---------LINWYIMTSDINHEETLSYFEQHDYFGYNPDNVHFFKQENMV 182
Query: 804 CITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVA 983
+ + G+ ++ + + P+GNGGV+ +L+ + L+ MAS G+K++ +DNVLV+V
Sbjct: 183 ALCETGQLVLNEQGYIMETPNGNGGVFKSLEKNGYLDKMASDGVKFIFLNNIDNVLVKVL 242
Query: 984 DPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMAS 1148
DP F G+ + +K ++ E VG V + TV+EY+ELDE++A+
Sbjct: 243 DPLFAGFTVVNDCDVTSKSIQPK-DGESVGRLVNQNSKD--TVLEYSELDEAVAN 294
>sp|Q2FEW1|URTF_STAA3 Probable uridylyltransferase SAUSA300_2130
OS=Staphylococcus aureus (strain USA300) GN=SAUSA300_2130 PE=3 SV=1
Length = 395
Score = 122 bits (304), Expect = 9e-027
Identities = 62/159 (38%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 681 IQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKA 860
IQWYIMTS HE T +FE+H YFG + + FF+Q + ++++GK I+ + +
Sbjct: 142 IQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMET 201
Query: 861 PDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKV 1040
P+GNGGV+ +L + LE+M++ G+KY+ +DNVLVRV DP F G+ ++ +K
Sbjct: 202 PNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVRVLDPLFAGFTVEHDYDITSKT 261
Query: 1041 VRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
++ P E VG V TV+EY+ELD +A+ N
Sbjct: 262 IQPK-PGESVGRLVNVDCKD--TVLEYSELDPEVANQFN 297
>sp|Q2FW81|URTF_STAA8 Probable uridylyltransferase SAOUHSC_02423
OS=Staphylococcus aureus (strain NCTC 8325) GN=SAOUHSC_02423 PE=3 SV=1
Length = 395
Score = 122 bits (304), Expect = 9e-027
Identities = 62/159 (38%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 681 IQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKA 860
IQWYIMTS HE T +FE+H YFG + + FF+Q + ++++GK I+ + +
Sbjct: 142 IQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMET 201
Query: 861 PDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKV 1040
P+GNGGV+ +L + LE+M++ G+KY+ +DNVLVRV DP F G+ ++ +K
Sbjct: 202 PNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVRVLDPLFAGFTVEHDYDITSKT 261
Query: 1041 VRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
++ P E VG V TV+EY+ELD +A+ N
Sbjct: 262 IQPK-PGESVGRLVNVDCKD--TVLEYSELDPEVANQFN 297
>sp|Q5HE34|URTF_STAAC Probable uridylyltransferase SACOL2161 OS=Staphylococcus
aureus (strain COL) GN=SACOL2161 PE=3 SV=1
Length = 395
Score = 122 bits (304), Expect = 9e-027
Identities = 62/159 (38%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 681 IQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKA 860
IQWYIMTS HE T +FE+H YFG + + FF+Q + ++++GK I+ + +
Sbjct: 142 IQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMET 201
Query: 861 PDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKV 1040
P+GNGGV+ +L + LE+M++ G+KY+ +DNVLVRV DP F G+ ++ +K
Sbjct: 202 PNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVRVLDPLFAGFTVEHDYDITSKT 261
Query: 1041 VRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
++ P E VG V TV+EY+ELD +A+ N
Sbjct: 262 IQPK-PGESVGRLVNVDCKD--TVLEYSELDPEVANQFN 297
>sp|Q99S95|URTF_STAAM Probable uridylyltransferase SAV2171 OS=Staphylococcus
aureus (strain Mu50 / ATCC 700699) GN=SAV2171 PE=1 SV=1
Length = 395
Score = 121 bits (301), Expect = 2e-026
Identities = 61/159 (38%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 681 IQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKA 860
IQWYIMTS HE T +FE+H YFG + + FF+Q + ++++GK I+ + +
Sbjct: 142 IQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMET 201
Query: 861 PDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKV 1040
P+GNGGV+ +L + LE+M++ G+KY+ +DNVLV+V DP F G+ ++ +K
Sbjct: 202 PNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKT 261
Query: 1041 VRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
++ P E VG V TV+EY+ELD +A+ N
Sbjct: 262 IQPK-PGESVGRLVNVDCKD--TVLEYSELDPEVANQFN 297
>sp|Q7A4A4|URTF_STAAN Probable uridylyltransferase SA1974 OS=Staphylococcus
aureus (strain N315) GN=SA1974 PE=1 SV=1
Length = 395
Score = 121 bits (301), Expect = 2e-026
Identities = 61/159 (38%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 681 IQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKA 860
IQWYIMTS HE T +FE+H YFG + + FF+Q + ++++GK I+ + +
Sbjct: 142 IQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMET 201
Query: 861 PDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKV 1040
P+GNGGV+ +L + LE+M++ G+KY+ +DNVLV+V DP F G+ ++ +K
Sbjct: 202 PNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKT 261
Query: 1041 VRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
++ P E VG V TV+EY+ELD +A+ N
Sbjct: 262 IQPK-PGESVGRLVNVDCKD--TVLEYSELDPEVANQFN 297
>sp|Q6G7E3|URTF_STAAS Probable uridylyltransferase SAS2072 OS=Staphylococcus
aureus (strain MSSA476) GN=SAS2072 PE=3 SV=1
Length = 395
Score = 121 bits (301), Expect = 2e-026
Identities = 61/159 (38%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 681 IQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKA 860
IQWYIMTS HE T +FE+H YFG + + FF+Q + ++++GK I+ + +
Sbjct: 142 IQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMET 201
Query: 861 PDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKV 1040
P+GNGGV+ +L + LE+M++ G+KY+ +DNVLV+V DP F G+ ++ +K
Sbjct: 202 PNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKT 261
Query: 1041 VRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
++ P E VG V TV+EY+ELD +A+ N
Sbjct: 262 IQPK-PGESVGRLVNVDCKD--TVLEYSELDPEVANQFN 297
>sp|Q7A0A0|URTF_STAAW Probable uridylyltransferase MW2097 OS=Staphylococcus
aureus (strain MW2) GN=MW2097 PE=3 SV=1
Length = 395
Score = 121 bits (301), Expect = 2e-026
Identities = 61/159 (38%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 681 IQWYIMTSPFTHEPTQKFFESHKYFGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKA 860
IQWYIMTS HE T +FE+H YFG + + FF+Q + ++++GK I+ + +
Sbjct: 142 IQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMET 201
Query: 861 PDGNGGVYAALKYSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKV 1040
P+GNGGV+ +L + LE+M++ G+KY+ +DNVLV+V DP F G+ ++ +K
Sbjct: 202 PNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKT 261
Query: 1041 VRKAYPQEKVGVFVRRGKGGPLTVVEYTELDESMASASN 1157
++ P E VG V TV+EY+ELD +A+ N
Sbjct: 262 IQPK-PGESVGRLVNVDCKD--TVLEYSELDPEVANQFN 297
>sp|Q6GEQ8|URTF_STAAR Probable uridylyltransferase SAR2262 OS=Staphylococcus
aureus (strain MRSA252) GN=SAR2262 PE=3 SV=1
Length = 395
Score = 120 bits (300), Expect = 3e-026
Identities = 67/195 (34%), Positives = 107/195 (54%), Gaps = 4/195 (2%)
Frame = +3
Query: 573 IGLPSGKSLFQIQAERILCVQRLAAQAMAGPTRSVAIQWYIMTSPFTHEPTQKFFESHKY 752
+G K F+I+ + +Q + + T IQWYIMTS HE T +FESH Y
Sbjct: 107 LGYKGPKGSFEIEGVSLFELQAKQLKELHRQT-GHKIQWYIMTSDINHEETLAYFESHNY 165
Query: 753 FGLEPGQVTFFQQGTLPCITKDGKFIMETPFSLAKAPDGNGGVYAALKYSRLLEDMASRG 932
FG + + FF+Q + +++ G+ I+ + + P+GNGGV+ +L + LE+M++ G
Sbjct: 166 FGYDQESIHFFKQDNIVALSEAGQLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNG 225
Query: 933 IKYVDCYGVDNVLVRVADPTFLGYFIDKGAASAAKVVRKAYPQEKVGVFVRRGKGGPLTV 1112
+KY+ +DNVLV+V DP F G+ ++ +K ++ P E VG V TV
Sbjct: 226 VKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPK-PGESVGRLVNVDCKD--TV 282
Query: 1113 VEYTELDESMASASN 1157
+EY+ELD +A+ N
Sbjct: 283 LEYSELDPEVANQFN 297
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,436,365,428
Number of Sequences: 518415
Number of Extensions: 75436365428
Number of Successful Extensions: 513409628
Number of sequences better than 0.0: 0
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