BLASTX 7.6.2
Query= UN18627 /QuerySize=1678
(1677 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5SP67|WDR26_DANRE WD repeat-containing protein 26 OS=Danio r... 328 8e-089
sp|Q9H7D7|WDR26_HUMAN WD repeat-containing protein 26 OS=Homo sa... 316 3e-085
sp|Q8C6G8|WDR26_MOUSE WD repeat-containing protein 26 OS=Mus mus... 315 6e-085
sp|Q28D01|WDR26_XENTR WD repeat-containing protein 26 OS=Xenopus... 314 2e-084
sp|Q9UT85|YIPC_SCHPO Uncharacterized WD repeat-containing protei... 279 6e-074
sp|Q7K0L4|WDR26_DROME WD repeat-containing protein 26 homolog OS... 237 3e-061
sp|Q2KIG2|WDR5_BOVIN WD repeat-containing protein 5 OS=Bos tauru... 133 4e-030
sp|P61964|WDR5_HUMAN WD repeat-containing protein 5 OS=Homo sapi... 133 4e-030
sp|P61965|WDR5_MOUSE WD repeat-containing protein 5 OS=Mus muscu... 133 4e-030
sp|Q498M4|WDR5_RAT WD repeat-containing protein 5 OS=Rattus norv... 133 4e-030
sp|Q9V3J8|WDS_DROME Protein will die slowly OS=Drosophila melano... 131 2e-029
sp|Q4V8C4|WDR5B_RAT WD repeat-containing protein 5B OS=Rattus no... 129 1e-028
sp|Q93847|YZLL_CAEEL Uncharacterized WD repeat-containing protei... 82 1e-014
>sp|Q5SP67|WDR26_DANRE WD repeat-containing protein 26 OS=Danio rerio GN=wdr26
PE=1 SV=1
Length = 576
Score = 328 bits (840), Expect = 8e-089
Identities = 183/479 (38%), Positives = 270/479 (56%), Gaps = 17/479 (3%)
Frame = -1
Query: 1671 SGIPLHRSFVETFLQQVKEGKWDESVVTLHRIGLV--DEKAVKSASFLLLEQKFLELLRF 1498
SG L S F V EG+WD++ L+ + + A+ FLLL+QK+LE L
Sbjct: 79 SGCRLEHSSATKFRNHVMEGEWDKAENDLNELKALMHSPNAIVRMKFLLLQQKYLEYLED 138
Query: 1497 DRIAEALGTLRNEIEPLRINTKRVHELASSLISPPSASGQGK-----ENVSSRSKVLEEL 1333
++ EAL LR E+ PL+ NT R+H L+ L+ + + K + SR ++L++L
Sbjct: 139 GKVLEALQVLRGELTPLKYNTDRIHVLSGYLMCSHAEDLKAKAEWEGKGAGSRCRLLDKL 198
Query: 1332 QSLLPASVIIPENRLETLVENSLHIQRNACVFHNT-LDSDL---SLYSDHQCGKHQIPSQ 1165
Q+ LP SV++P RL+TL+ ++ +QR+ C++HNT LDS L SL DH C + Q P
Sbjct: 199 QTYLPPSVMLPPRRLQTLLRQAVELQRDRCLYHNTKLDSSLDSVSLLLDHVCSRKQFPCY 258
Query: 1164 TVQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGH-MSLKHKLVGHQKPVTA 988
T QIL H +EVWF +FS++G LA+ SKD T IIW+++ D H + L L GH V+
Sbjct: 259 TQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVEPDTHQLKLLRTLEGHAYGVSY 318
Query: 987 VLWSPDDRQVLTCGAEEV--IRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIAGMT 814
+ WSPDD ++ CG ++ + W+V +G+ + S W DGK + G
Sbjct: 319 LAWSPDDVYLIACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQ 378
Query: 813 DRSICMWDLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREATFERLIE 634
DLDG +E W+G R Q + M D L S + + T +++
Sbjct: 379 RGQFYQCDLDGNLLESWEGVRVQCL--WCMGDGRTVLASDTHQRIRGYSFEDLTDRNIVQ 436
Query: 633 EEDTITSFSLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSCFGGHEQ 454
E+ I SF++S + + L+N+ Q + LW ++ D +V +Y+G + + I SCFGGH +
Sbjct: 437 EDHPIMSFTVSKNGRLALLNVATQGVHLWDLQ-DRVLVRKYQGVTQGFYTIHSCFGGHNE 495
Query: 453 GFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPTNLHMMASASDDGTIRIWG 277
FIASGSED +VYIWH+ + I+EL GH VNCV W+P +MASASDDGT+RIWG
Sbjct: 496 DFIASGSEDHKVYIWHKRSELPIVELTGHTRTVNCVSWNPCIPSLMASASDDGTVRIWG 554
>sp|Q9H7D7|WDR26_HUMAN WD repeat-containing protein 26 OS=Homo sapiens GN=WDR26
PE=1 SV=3
Length = 661
Score = 316 bits (809), Expect = 3e-085
Identities = 173/434 (39%), Positives = 260/434 (59%), Gaps = 17/434 (3%)
Frame = -1
Query: 1539 FLLLEQKFLELLRFDRIAEALGTLRNEIEPLRINTKRVHELASSLISPPSASGQGK---- 1372
FLLL+QK+LE L ++ EAL LR E+ PL+ NT+R+H L+ L+ + + K
Sbjct: 213 FLLLQQKYLEYLEDGKVLEALQVLRCELTPLKYNTERIHVLSGYLMCSHAEDLRAKAEWE 272
Query: 1371 -ENVSSRSKVLEELQSLLPASVIIPENRLETLVENSLHIQRNACVFHNT-LDSDL---SL 1207
+ +SRSK+L++LQ+ LP SV++P RL+TL+ ++ +QR+ C++HNT LD++L SL
Sbjct: 273 GKGTASRSKLLDKLQTYLPPSVMLPPRRLQTLLRQAVELQRDRCLYHNTKLDNNLDSVSL 332
Query: 1206 YSDHQCGKHQIPSQTVQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGH-MS 1030
DH C + Q P T QIL H +EVWF +FS++G LA+ SKD T IIW++ D H +
Sbjct: 333 LIDHVCSRRQFPCYTQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLK 392
Query: 1029 LKHKLVGHQKPVTAVLWSPDDRQVLTCGAEEV--IRRWDVDSGDCAHTYEKGGGIGPISC 856
L L GH V+ + WSPDD ++ CG ++ + W+V +G+ + S
Sbjct: 393 LLKTLEGHAYGVSYIAWSPDDNYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSV 452
Query: 855 GWYADGKGIIAGMTDRSICMWDLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVI 676
W DGK + G DLDG ++ W+G R Q + ++ DGK +++ I
Sbjct: 453 AWNPDGKRFVTGGQRGQFYQCDLDGNLLDSWEGVRVQCLWCLS---DGKTVLASDTHQRI 509
Query: 675 SLFDREATFER-LIEEEDTITSFSLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHK 499
++ E +R +++E+ I SF++S + + L+N+ Q + LW ++ D +V +Y+G
Sbjct: 510 RGYNFEDLTDRNIVQEDHPIMSFTISKNGRLALLNVATQGVHLWDLQ-DRVLVRKYQGVT 568
Query: 498 RSRFLIRSCFGGHEQGFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPTNLHM 319
+ + I SCFGGH + FIASGSED +VYIWH+ + I EL GH VNCV W+P M
Sbjct: 569 QGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSM 628
Query: 318 MASASDDGTIRIWG 277
MASASDDGT+RIWG
Sbjct: 629 MASASDDGTVRIWG 642
>sp|Q8C6G8|WDR26_MOUSE WD repeat-containing protein 26 OS=Mus musculus GN=Wdr26
PE=1 SV=2
Length = 641
Score = 315 bits (807), Expect = 6e-085
Identities = 172/433 (39%), Positives = 254/433 (58%), Gaps = 15/433 (3%)
Frame = -1
Query: 1539 FLLLEQKFLELLRFDRIAEALGTLRNEIEPLRINTKRVHELASSLISPPSASGQGK---- 1372
FLLL+QK+LE L ++ EAL LR E+ PL+ NT+R+H L+ L+ + + K
Sbjct: 193 FLLLQQKYLEYLEDGKVLEALQVLRCELTPLKYNTERIHVLSGYLMCSHAEDLRAKAEWE 252
Query: 1371 -ENVSSRSKVLEELQSLLPASVIIPENRLETLVENSLHIQRNACVFHNT-LDSDL---SL 1207
+ +SRSK+L++LQ+ LP SV++P RL+TL+ ++ +QR+ C++HNT LD++L SL
Sbjct: 253 GKGTASRSKLLDKLQTYLPPSVMLPPRRLQTLLRQAVELQRDRCLYHNTKLDNNLDSVSL 312
Query: 1206 YSDHQCGKHQIPSQTVQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGH-MS 1030
DH C + Q P T QIL H +EVWF +FS++G LA+ SKD T IIW++ D H +
Sbjct: 313 LIDHVCSRRQFPCYTQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLK 372
Query: 1029 LKHKLVGHQKPVTAVLWSPDDRQVLTCGAEEV--IRRWDVDSGDCAHTYEKGGGIGPISC 856
L L GH V+ + WSPDD ++ CG ++ + W+V +G+ + S
Sbjct: 373 LLKTLEGHAYGVSYIAWSPDDSYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSV 432
Query: 855 GWYADGKGIIAGMTDRSICMWDLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVI 676
W DGK + G DLDG ++ W+G R Q + ++D L S V
Sbjct: 433 AWNPDGKRFVTGGQRGQFYQCDLDGNLLDSWEGVRVQCL--WCLSDGKTVLASDTHQRVR 490
Query: 675 SLFDREATFERLIEEEDTITSFSLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKR 496
+ T +++E+ I SF++S + + L+N+ Q + LW ++ D +V +Y+G +
Sbjct: 491 GYNFEDLTDRNIVQEDHPIMSFTISKNGRLALLNVATQGVHLWDLQ-DRVLVRKYQGVTQ 549
Query: 495 SRFLIRSCFGGHEQGFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPTNLHMM 316
+ I SCFGGH + FIASGSED +VYIWH+ + I EL GH VNCV W+P MM
Sbjct: 550 GFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMM 609
Query: 315 ASASDDGTIRIWG 277
ASASDDGT+RIWG
Sbjct: 610 ASASDDGTVRIWG 622
>sp|Q28D01|WDR26_XENTR WD repeat-containing protein 26 OS=Xenopus tropicalis
GN=wdr26 PE=2 SV=2
Length = 614
Score = 314 bits (803), Expect = 2e-084
Identities = 172/440 (39%), Positives = 262/440 (59%), Gaps = 19/440 (4%)
Frame = -1
Query: 1554 VKSASFLLLEQKFLELLRFDRIAEALGTLRNEIEPLRINTKRVHELASSLISP------P 1393
++ FLLL+QK+LE L ++ EAL LR E+ PL+ NT+R+H L+ L+
Sbjct: 161 IRRMKFLLLQQKYLEYLEDGKVLEALQVLRCELTPLKYNTERIHVLSGYLMCSHADDLRA 220
Query: 1392 SASGQGKENVSSRSKVLEELQSLLPASVIIPENRLETLVENSLHIQRNACVFHNT-LDSD 1216
A +GK +SRSK+L++LQ+ LP SV++P RL+TL+ ++ +QR+ C++HNT LD++
Sbjct: 221 KAEWEGK-GTASRSKLLDKLQTYLPPSVMLPPRRLQTLLRQAVELQRDRCLYHNTKLDNN 279
Query: 1215 L---SLYSDHQCGKHQIPSQTVQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKA 1045
L SL DH C + Q P T Q+L H +EVWF +FS++G LA+ SKD T IIW++
Sbjct: 280 LDSVSLLIDHVCSRKQFPCFTQQVLTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDP 339
Query: 1044 DGH-MSLKHKLVGHQKPVTAVLWSPDDRQVLTCGAEEV--IRRWDVDSGDCAHTYEKGGG 874
D H + L L GH V+ + WSPDD ++ CG ++ + W+V +G+ +
Sbjct: 340 DTHQLKLLKTLEGHAYGVSYLAWSPDDNYLIACGPDDCSELWLWNVQTGELRTKMSQSHE 399
Query: 873 IGPISCGWYADGKGIIAGMTDRSICMWDLDGREMECWKGQRTQKVSDIAMTDDGKWLVSV 694
S W DGK + G DLDG ++ W+G R Q + ++ DGK +++
Sbjct: 400 DSLTSVAWNPDGKRFVTGGQRGQFYQCDLDGNLLDSWEGVRVQCLWCLS---DGKTVLAS 456
Query: 693 CKDSVISLFDREATFER-LIEEEDTITSFSLSNDNKYVLVNLQNQEIRLWSIESDPKIVT 517
I ++ E +R +++E+ I SF++S + + L+N+ Q + LW ++ D +V
Sbjct: 457 DTHQRIRGYNFEDLTDRNIVQEDHPIMSFTISRNGRLALLNVATQGVHLWDLQ-DRVLVR 515
Query: 516 RYKGHKRSRFLIRSCFGGHEQGFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWS 337
+Y+G + + I SCFGGH + FIASGSED +VY+WH+ + I EL GH VNCV W+
Sbjct: 516 KYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYVWHKRSELPIAELTGHTRTVNCVSWN 575
Query: 336 PTNLHMMASASDDGTIRIWG 277
P +MASASDDGT+RIWG
Sbjct: 576 PQIPSLMASASDDGTVRIWG 595
>sp|Q9UT85|YIPC_SCHPO Uncharacterized WD repeat-containing protein C343.04c
OS=Schizosaccharomyces pombe GN=SPAC343.04c PE=2 SV=1
Length = 507
Score = 279 bits (712), Expect = 6e-074
Identities = 167/489 (34%), Positives = 259/489 (52%), Gaps = 33/489 (6%)
Frame = -1
Query: 1677 EESGIPLHRSFVETFLQQVKEGKWDESVVTLHRIGLVDEKAVKSASFLLLEQKFLELLRF 1498
+E+G+ V+ Q V +G W + + L DE K A FLL +Q+ LEL R
Sbjct: 33 KETGLVSETEDVKRLKQAVLQGDWITAEAAFSIMQLRDESKRKEAQFLLQKQRCLELARS 92
Query: 1497 DRIAEALGTLRNEIEPLRINTKRVHELASSLISPPSAS--------GQGKENVSSRSKVL 1342
I EA+ L+N E N K L S ++ + S G G ++R +L
Sbjct: 93 GAICEAIYVLQN-FESTDFN-KEKERLVSIILESNNKSNNELITKNGYG----NTRLDLL 146
Query: 1341 EELQSLLPASVIIPENRLETLVENSLHIQRNACVFHNTLDSDLSLYSDHQCGKHQIPSQT 1162
+L + +++P+ RLE L++ + Q ++ V+HN L + S SD++ ++P++
Sbjct: 147 NQLSEYISPEILLPKRRLEHLLQQAKDYQVSSQVYHNVL-KNFSFLSDYKADPSELPTKE 205
Query: 1161 VQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGHMSLKHKLVGHQKPVTAVL 982
+ H+DEVW + +SHNG+YLAS+SKD+TAII+++ ++ +L+GH V +
Sbjct: 206 YHVFHDHSDEVWQISYSHNGRYLASASKDKTAIIFDVV---NLKRVFRLIGHIDTVAYIR 262
Query: 981 WSPDDRQVLTCGAEEVIRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIAGMTDRSI 802
WSPDDR +L+C ++ + WD +G+ Y+ G + C W DG I G D I
Sbjct: 263 WSPDDRYLLSCSCDKSVILWDAFTGEKLRDYKHGFSVS--CCCWLPDGLSFITGSPDCHI 320
Query: 801 CMWDLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREATFE-------- 646
W L+G + W+ + D+A+T DG L V + +I+ D+
Sbjct: 321 THWSLNGEILYKWE---DVNIYDMALTSDGTKLYIVGFEQLINAEDKHIAIYSVETRECI 377
Query: 645 RLIEEEDTITSFSLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSCFG 466
+ I + +TS LS D+KY L NL+ LW +E + +IV +Y GHK FLI SCFG
Sbjct: 378 KKISLQSKVTSICLSKDSKYALTNLEPHTTFLWDLEEN-RIVRQYMGHKLGNFLIGSCFG 436
Query: 465 GHEQGFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPTNLHMMASASDDGTIR 286
G + F+ SGSED ++ IWHR +GKL+ L GH VN V ++P + + ASA DD T+R
Sbjct: 437 GKDDTFVLSGSEDDKIRIWHRESGKLLATLSGHVKCVNYVAYNPVDPYQFASAGDDNTVR 496
Query: 285 IWGLDRINP 259
IW ++ NP
Sbjct: 497 IWS-NKDNP 504
>sp|Q7K0L4|WDR26_DROME WD repeat-containing protein 26 homolog OS=Drosophila
melanogaster GN=CG7611 PE=1 SV=1
Length = 630
Score = 237 bits (603), Expect = 3e-061
Identities = 142/383 (37%), Positives = 216/383 (56%), Gaps = 19/383 (4%)
Frame = -1
Query: 1389 ASGQGKENVSSRSKVLEELQSLLPASVIIPENRLETLVENSLHIQRNACVFHN----TLD 1222
A +GK + SR+ V+E LQ+ +P SV++ RL TL++ ++ +Q C H+ T
Sbjct: 228 AKWEGK-GILSRALVMERLQTFMPPSVMMSPRRLRTLLQQAVELQSQHCPCHDMAWETNL 286
Query: 1221 SDLSLYSDHQCGKHQIPSQTVQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKAD 1042
+SL +DH C P QT+QIL H DEVWF +FS +G LA+ SKD T IIW++
Sbjct: 287 ETVSLLTDHCCTTDGFPMQTIQILTDHCDEVWFCKFSPDGLKLATGSKDSTVIIWDVD-P 345
Query: 1041 GHMSLKHKLV---GHQKPVTAVLWSPDDRQVLTCGAEE--VIRRWDVDSGDCAHTYEKGG 877
++LKH+ V Q V+ V WSPD + +L G E+ + W+VD G + +
Sbjct: 346 YKLTLKHRRVLDGQAQLSVSFVSWSPDSKLILVGGTEDSHELYIWNVDDGKLVVKFSQSL 405
Query: 876 GIGPISCGWYA-DGKGIIAGMTDRSICMWDLDGREMECWKGQRTQKVSDIAMTDDGKWLV 700
++CG ++ DG + G + + DL+G ++ W+G R V+ IA D K ++
Sbjct: 406 E-DSLACGAFSRDGARFVCGGQKGQLYLCDLNGTIVDSWEGVR---VNSIAFRADNKTIL 461
Query: 699 SVCKDSVIS--LFDREATFERLIEEEDTITSFSLSNDNKYVLVNLQNQEIRLWSIESDPK 526
+ I FD + ++ E I +FS+++ ++ L+N+ NQ + LW IE D
Sbjct: 462 AADNHYRIRGYNFDSPRSDFDILREPHPIMTFSINSADRLALLNVSNQGLHLWDIE-DKC 520
Query: 525 IVTRYKGHKRSRFLIRSCFGGHEQGFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCV 346
+V R++G ++S F I SCFGG + F+ASGSED VYIWH + + +L GH VNCV
Sbjct: 521 LVRRFQGIRQSNFAIHSCFGGVNESFVASGSEDKVVYIWHIKREEPLAKLAGHTKTVNCV 580
Query: 345 GWSPTNLHMMASASDDGTIRIWG 277
W+P ++ASASDD T+RIWG
Sbjct: 581 SWNPVYPSLLASASDDATVRIWG 603
>sp|Q2KIG2|WDR5_BOVIN WD repeat-containing protein 5 OS=Bos taurus GN=WDR5 PE=2
SV=1
Length = 334
Score = 133 bits (334), Expect = 4e-030
Identities = 90/298 (30%), Positives = 146/298 (48%), Gaps = 9/298 (3%)
Frame = -1
Query: 1152 LESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGHMSLKHKLVGHQKPVTAVLWSP 973
L HT V ++FS NG++LASSS D+ IW DG + + GH+ ++ V WS
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG-AYDG--KFEKTISGHKLGISDVAWSS 97
Query: 972 DDRQVLTCGAEEVIRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIAGMTDRSICMW 793
D +++ ++ ++ WDV SG C T KG C + I++G D S+ +W
Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 792 DLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREA--TFERLIEEEDTI 619
D+ + + VS + DG +VS D + ++D + + LI++++
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 618 TSF-SLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSCFGGHEQGFIA 442
SF S + KY+L + ++LW S K + Y GHK ++ I + F +I
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDY-SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 441 SGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPT-NLHMMASASDDGTIRIWGLD 271
SGSED VYIW+ T +++ +L GH V PT N+ A+ +D TI++W D
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 333
>sp|P61964|WDR5_HUMAN WD repeat-containing protein 5 OS=Homo sapiens GN=WDR5
PE=1 SV=1
Length = 334
Score = 133 bits (334), Expect = 4e-030
Identities = 90/298 (30%), Positives = 146/298 (48%), Gaps = 9/298 (3%)
Frame = -1
Query: 1152 LESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGHMSLKHKLVGHQKPVTAVLWSP 973
L HT V ++FS NG++LASSS D+ IW DG + + GH+ ++ V WS
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG-AYDG--KFEKTISGHKLGISDVAWSS 97
Query: 972 DDRQVLTCGAEEVIRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIAGMTDRSICMW 793
D +++ ++ ++ WDV SG C T KG C + I++G D S+ +W
Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 792 DLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREA--TFERLIEEEDTI 619
D+ + + VS + DG +VS D + ++D + + LI++++
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 618 TSF-SLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSCFGGHEQGFIA 442
SF S + KY+L + ++LW S K + Y GHK ++ I + F +I
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDY-SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 441 SGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPT-NLHMMASASDDGTIRIWGLD 271
SGSED VYIW+ T +++ +L GH V PT N+ A+ +D TI++W D
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 333
>sp|P61965|WDR5_MOUSE WD repeat-containing protein 5 OS=Mus musculus GN=Wdr5
PE=2 SV=1
Length = 334
Score = 133 bits (334), Expect = 4e-030
Identities = 90/298 (30%), Positives = 146/298 (48%), Gaps = 9/298 (3%)
Frame = -1
Query: 1152 LESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGHMSLKHKLVGHQKPVTAVLWSP 973
L HT V ++FS NG++LASSS D+ IW DG + + GH+ ++ V WS
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG-AYDG--KFEKTISGHKLGISDVAWSS 97
Query: 972 DDRQVLTCGAEEVIRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIAGMTDRSICMW 793
D +++ ++ ++ WDV SG C T KG C + I++G D S+ +W
Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 792 DLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREA--TFERLIEEEDTI 619
D+ + + VS + DG +VS D + ++D + + LI++++
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 618 TSF-SLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSCFGGHEQGFIA 442
SF S + KY+L + ++LW S K + Y GHK ++ I + F +I
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDY-SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 441 SGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPT-NLHMMASASDDGTIRIWGLD 271
SGSED VYIW+ T +++ +L GH V PT N+ A+ +D TI++W D
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 333
>sp|Q498M4|WDR5_RAT WD repeat-containing protein 5 OS=Rattus norvegicus GN=Wdr5
PE=2 SV=1
Length = 334
Score = 133 bits (334), Expect = 4e-030
Identities = 90/298 (30%), Positives = 146/298 (48%), Gaps = 9/298 (3%)
Frame = -1
Query: 1152 LESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGHMSLKHKLVGHQKPVTAVLWSP 973
L HT V ++FS NG++LASSS D+ IW DG + + GH+ ++ V WS
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG-AYDG--KFEKTISGHKLGISDVAWSS 97
Query: 972 DDRQVLTCGAEEVIRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIAGMTDRSICMW 793
D +++ ++ ++ WDV SG C T KG C + I++G D S+ +W
Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 792 DLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREA--TFERLIEEEDTI 619
D+ + + VS + DG +VS D + ++D + + LI++++
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 618 TSF-SLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSCFGGHEQGFIA 442
SF S + KY+L + ++LW S K + Y GHK ++ I + F +I
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDY-SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 441 SGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPT-NLHMMASASDDGTIRIWGLD 271
SGSED VYIW+ T +++ +L GH V PT N+ A+ +D TI++W D
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSD 333
>sp|Q9V3J8|WDS_DROME Protein will die slowly OS=Drosophila melanogaster GN=wds
PE=2 SV=1
Length = 361
Score = 131 bits (328), Expect = 2e-029
Identities = 92/308 (29%), Positives = 155/308 (50%), Gaps = 14/308 (4%)
Frame = -1
Query: 1173 PSQTVQI-LESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGHMSLKHKLVGHQKP 997
P+ T++ L HT V ++FS NG++LASSS D+ IW DG + + GH+
Sbjct: 60 PNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWG-AYDG--KFEKTISGHKLG 116
Query: 996 VTAVLWSPDDRQVLTCGAEEVIRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIAGM 817
++ V WS D R +++ ++ ++ W++ +G T KG C + I++G
Sbjct: 117 ISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTL-KGHSNYVFCCNFNPQSNLIVSGS 175
Query: 816 TDRSICMWDLDGREMECWK--GQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREA--TF 649
D S+ +WD+ R +C K + VS + DG +VS D + ++D +
Sbjct: 176 FDESVRIWDV--RTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCL 233
Query: 648 ERLIEEEDTITSF-SLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSC 472
+ LI++++ SF S + KY+L + ++LW S K + Y GHK ++ I +
Sbjct: 234 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY-SKGKCLKTYTGHKNEKYCIFAN 292
Query: 471 FGGHEQGFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPT-NLHMMASASDDG 295
F +I SGSED VYIW+ + +++ +L GH V C PT N+ A+ +D
Sbjct: 293 FSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDK 352
Query: 294 TIRIWGLD 271
TI++W D
Sbjct: 353 TIKLWKSD 360
>sp|Q4V8C4|WDR5B_RAT WD repeat-containing protein 5B OS=Rattus norvegicus
GN=Wdr5b PE=2 SV=1
Length = 328
Score = 129 bits (322), Expect = 1e-028
Identities = 88/308 (28%), Positives = 149/308 (48%), Gaps = 10/308 (3%)
Frame = -1
Query: 1179 QIPSQTVQI-LESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEIKADGHMSLKHKLVGHQ 1003
Q P+ +++ L H+ + ++FS NG++LASS+ D IIW DG K L GH
Sbjct: 25 QKPNYALRLTLAGHSAAISSVKFSPNGEWLASSAADALIIIWG-AYDG--KCKKTLYGHS 81
Query: 1002 KPVTAVLWSPDDRQVLTCGAEEVIRRWDVDSGDCAHTYEKGGGIGPISCGWYADGKGIIA 823
++ V WS D ++++ ++ ++ WDV SG C T KG C + I++
Sbjct: 82 LEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTL-KGHSDFVFCCDFNPPSNLIVS 140
Query: 822 GMTDRSICMWDLDGREMECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREA--TF 649
G D S+ +W++ + + +S + +G +VS D + ++D +
Sbjct: 141 GSFDESVKIWEVKTGKCLKTLSAHSDPISAVHFHCNGSLIVSGSYDGLCRIWDAASGQCL 200
Query: 648 ERLIEEEDTITSF-SLSNDNKYVLVNLQNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSC 472
L +E + SF S + KY+L + ++LW S + + Y GHK ++ I +
Sbjct: 201 RTLADEGNPPVSFVKFSPNGKYILTATLDSTLKLWDY-SRGRCLKTYTGHKNEKYCIFAS 259
Query: 471 FGGHEQGFIASGSEDLQVYIWHRSTGKLIIELPGHAGAVNCVGWSPT-NLHMMASASDDG 295
F + ++ SGSED VYIW+ T +++ L GH V PT N+ A+ +D
Sbjct: 260 FSVTGRKWVVSGSEDNMVYIWNLQTKEIVQRLQGHTDVVISAACHPTENIIASAALENDK 319
Query: 294 TIRIWGLD 271
TI+IW D
Sbjct: 320 TIKIWSSD 327
>sp|Q93847|YZLL_CAEEL Uncharacterized WD repeat-containing protein K04G11.4
OS=Caenorhabditis elegans GN=K04G11.4 PE=2 SV=1
Length = 395
Score = 82 bits (201), Expect = 1e-014
Identities = 50/158 (31%), Positives = 81/158 (51%), Gaps = 5/158 (3%)
Frame = -1
Query: 741 VSDIAMTDDGKWLVSVCKDSVISLFDRE--ATFERLIEEE-DTITSFSLSNDNKYVLVNL 571
VS + DG +L S D ++ ++D + LI+EE IT S + KY+L +
Sbjct: 235 VSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASN 294
Query: 570 QNQEIRLWSIESDPKIVTRYKGHKRSRFLIRSCFGGHEQGFIASGSEDLQVYIWHRSTGK 391
N ++LW + +++ Y GH+ S++ + + F +I SGSED +VYIW+ T +
Sbjct: 295 LNNTLKLWDYQK-LRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNLQTRE 353
Query: 390 LIIELPGHAGAVNCVGWSP-TNLHMMASASDDGTIRIW 280
++ L GH AV C P N+ A+ D I+IW
Sbjct: 354 ILQTLDGHNTAVMCTDCHPGQNIIASAALEPDMRIKIW 391
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,436,365,428
Number of Sequences: 518415
Number of Extensions: 75436365428
Number of Successful Extensions: 513409628
Number of sequences better than 0.0: 0
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