BLASTX 7.6.2

Query= UN18687 /QuerySize=695
        (694 letters)

Database: UniProt/SwissProt;
          518,415 sequences; 182,829,261 total letters
                                                                  Score    E
Sequences producing significant alignments:                       (bits) Value

sp|O15514|RPB4_HUMAN DNA-directed RNA polymerase II subunit RPB4...    106   2e-022
sp|Q9D7M8|RPB4_MOUSE DNA-directed RNA polymerase II subunit RPB4...    106   2e-022
sp|Q9VEA5|RPB4_DROME DNA-directed RNA polymerase II 16 kDa polyp...     91   6e-018
sp|Q54S04|RPB4_DICDI DNA-directed RNA polymerase II subunit rpb4...     78   4e-014
sp|O74825|RPB4_SCHPO DNA-directed RNA polymerase II subunit rpb4...     66   2e-010

>sp|O15514|RPB4_HUMAN DNA-directed RNA polymerase II subunit RPB4 OS=Homo
        sapiens GN=POLR2D PE=1 SV=1

          Length = 142

 Score =  106 bits (263), Expect = 2e-022
 Identities = 53/130 (40%), Positives = 89/130 (68%), Gaps = 5/130 (3%)
 Frame = +2

Query:  77 SGEEEENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQY 256
           +G+ EE+A++L    EF  A+ L+N EV ++LEH+ +Q +   ++   ++S+VF K+L Y
Sbjct:  10 AGDVEEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDE--QELSEVFMKTLNY 67

Query: 257 VKRFSRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSD 436
             RFSR+KN + +  VR +L + +L +FEL  L NLCPETAEE+ A++PSL+ +     D
Sbjct:  68 TARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGR---FED 124

Query: 437 EAIEKMLNDL 466
           E ++++L+D+
Sbjct: 125 EELQQILDDI 134

>sp|Q9D7M8|RPB4_MOUSE DNA-directed RNA polymerase II subunit RPB4 OS=Mus
        musculus GN=Polr2d PE=2 SV=2

          Length = 142

 Score =  106 bits (263), Expect = 2e-022
 Identities = 53/130 (40%), Positives = 89/130 (68%), Gaps = 5/130 (3%)
 Frame = +2

Query:  77 SGEEEENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQY 256
           +G+ EE+A++L    EF  A+ L+N EV ++LEH+ +Q +   ++   ++S+VF K+L Y
Sbjct:  10 AGDVEEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDE--QELSEVFMKTLNY 67

Query: 257 VKRFSRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSD 436
             RFSR+KN + +  VR +L + +L +FEL  L NLCPETAEE+ A++PSL+ +     D
Sbjct:  68 TARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGR---FED 124

Query: 437 EAIEKMLNDL 466
           E ++++L+D+
Sbjct: 125 EELQQILDDI 134

>sp|Q9VEA5|RPB4_DROME DNA-directed RNA polymerase II 16 kDa polypeptide
        OS=Drosophila melanogaster GN=Rpb4 PE=1 SV=5

          Length = 139

 Score =  91 bits (224), Expect = 6e-018
 Identities = 46/126 (36%), Positives = 78/126 (61%), Gaps = 5/126 (3%)
 Frame = +2

Query:  89 EENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQYVKRF 268
           +E+AA+L+   EF  A+ L+  EV ++L+H+  Q +   E+   + S+VF K+  Y   F
Sbjct:  11 DEDAADLQFPKEFENAETLLISEVHMLLDHRKRQNESADEE--QEFSEVFMKTYAYTDSF 68

Query: 269 SRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSDEAIE 448
            ++KN + +   R +L + +L +FEL  LGNLCPE  EEA A++PSL+ +     DE + 
Sbjct:  69 RKFKNKETIMSARSLLMQKKLHKFELAALGNLCPEAPEEAKALIPSLEGR---FEDEELR 125

Query: 449 KMLNDL 466
           ++L+D+
Sbjct: 126 QILDDI 131

>sp|Q54S04|RPB4_DICDI DNA-directed RNA polymerase II subunit rpb4
        OS=Dictyostelium discoideum GN=polr2d PE=3 SV=1

          Length = 155

 Score =  78 bits (191), Expect = 4e-014
 Identities = 36/85 (42%), Positives = 58/85 (68%), Gaps = 4/85 (4%)
 Frame = +2

Query: 215 MNQVSQVFEKSLQYVKRFSRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVA 394
           +N + + F K+L Y ++FSRYKN  +++QVR  LS+  L EFE+  L NLCPE ++EA +
Sbjct:  69 INDIIRTFHKTLAYAEKFSRYKNKTSIKQVRTALSKQNLEEFEIASLANLCPEISDEAKS 128

Query: 395 MVPSLKTKGRAHSDEAIEKMLNDLS 469
           ++PSLK       D+ ++ +L++LS
Sbjct: 129 LIPSLKKM----EDDELQAILDELS 149

>sp|O74825|RPB4_SCHPO DNA-directed RNA polymerase II subunit rpb4
        OS=Schizosaccharomyces pombe GN=rpb4 PE=1 SV=1

          Length = 135

 Score =  66 bits (160), Expect = 2e-010
 Identities = 42/132 (31%), Positives = 73/132 (55%), Gaps = 5/132 (3%)
 Frame = +2

Query:  89 EENAAELKIGDEFLKAKCLMNCEVSLILEHKYEQLQQVSEDPMNQVSQVFEKSLQYVKRF 268
           EE+AA+LK+G EF     L   E  +++E    Q  + +   +  ++ V +K++ Y   F
Sbjct:   7 EEDAAQLKLGPEFENEDMLTVSEAKILIETVLAQRARETNGEI-PMTDVMKKTVAYFNVF 65

Query: 269 SRYKNPDAVRQVREILSRHQLTEFELCVLGNLCPETAEEAVAMVPSLKTKGRAHSDEAIE 448
           +R+K  +A      IL  ++  +FE   LG LC E AEEA  ++PSL  K     D+ ++
Sbjct:  66 ARFKTAEATYACERILG-NRFHKFERAQLGTLCCEDAEEARTLIPSLANK---IDDQNLQ 121

Query: 449 KMLNDLSLVKRF 484
            +L++LS +++F
Sbjct: 122 GILDELSTLRKF 133

  Database: UniProt/SwissProt
    Posted date:  Sat Aug 07 14:36:18 2010
  Number of letters in database: 182,829,261
  Number of sequences in database:  518,415

Lambda     K     H
   0.267   0.041    0.140
Gapped
Lambda     K     H
   0.267   0.041    0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,378,909,851
Number of Sequences: 518415
Number of Extensions: 78378909851
Number of Successful Extensions: 523441567
Number of sequences better than 0.0: 0