BLASTX 7.6.2
Query= UN18723 /QuerySize=2319
(2318 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q96321|IMA1_ARATH Importin subunit alpha-1 OS=Arabidopsis tha... 874 5e-253
sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryza sativa ... 822 4e-237
sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryza sativa ... 818 4e-236
sp|O22478|IMA_SOLLC Importin subunit alpha OS=Solanum lycopersic... 800 1e-230
sp|O04294|IMA2_ARATH Importin subunit alpha-2 OS=Arabidopsis tha... 730 1e-209
sp|Q76P29|IMAB_DICDI Importin subunit alpha-B OS=Dictyostelium d... 560 2e-158
sp|O35345|IMA7_MOUSE Importin subunit alpha-7 OS=Mus musculus GN... 512 5e-144
sp|Q0V7M0|IMA7_BOVIN Importin subunit alpha-7 OS=Bos taurus GN=K... 512 8e-144
sp|O60684|IMA7_HUMAN Importin subunit alpha-7 OS=Homo sapiens GN... 508 1e-142
sp|Q5RBV0|IMA7_PONAB Importin subunit alpha-7 OS=Pongo abelii GN... 508 1e-142
sp|Q5ZML1|IMA1_CHICK Importin subunit alpha-1 OS=Gallus gallus G... 486 5e-136
sp|Q503E9|IMA5_DANRE Importin subunit alpha-6 OS=Danio rerio GN=... 482 7e-135
sp|A2VE08|IMA1_BOVIN Importin subunit alpha-1 OS=Bos taurus GN=K... 481 9e-135
sp|P52294|IMA1_HUMAN Importin subunit alpha-1 OS=Homo sapiens GN... 481 1e-134
sp|Q5R909|IMA1_PONAB Importin subunit alpha-1 OS=Pongo abelii GN... 480 3e-134
sp|P83953|IMA1_RAT Importin subunit alpha-1 OS=Rattus norvegicus... 478 1e-133
sp|Q60960|IMA1_MOUSE Importin subunit alpha-1 OS=Mus musculus GN... 477 2e-133
sp|Q56R16|IMA5_RAT Importin subunit alpha-6 OS=Rattus norvegicus... 477 2e-133
sp|O00629|IMA4_HUMAN Importin subunit alpha-4 OS=Homo sapiens GN... 432 6e-120
sp|O35343|IMA4_MOUSE Importin subunit alpha-4 OS=Mus musculus GN... 432 6e-120
>sp|Q96321|IMA1_ARATH Importin subunit alpha-1 OS=Arabidopsis thaliana GN=KAP1
PE=2 SV=2
Length = 532
Score = 874 bits (2258), Expect = 5e-253
Identities = 450/531 (84%), Positives = 476/531 (89%), Gaps = 4/531 (0%)
Frame = +1
Query: 208 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQ-LP 384
MSLRPNA+TEVRRNRYKVAVDAEEGRRRREDNMVEIRK+K EESL+KKRREG Q Q P
Sbjct: 1 MSLRPNAKTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLMKKRREGMQALQGFP 60
Query: 385 QVSASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEAGVVPRF 564
SA+SV+KKL+SL MV GV SDD +LQLE+TTQFRKLLSIERSPPIEEVI AGVVPRF
Sbjct: 61 SASAASVDKKLDSLKDMVAGVWSDDPALQLESTTQFRKLLSIERSPPIEEVISAGVVPRF 120
Query: 565 VEFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVW 744
VEFLK+EDYP +QFEAAWALTNIASGTS+HTKVVI H AVPIFVQLLAS SDDVREQAVW
Sbjct: 121 VEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVW 180
Query: 745 ALGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGKPQPPFDQV 924
ALGNVAGDSP+CRDLVL GALLPLL+QLNEHAKLSMLRNATWTLSNFCRGKPQP FDQV
Sbjct: 181 ALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFCRGKPQPHFDQV 240
Query: 925 CPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSV 1104
PALPALERLIHS DEEVLTDACWALSYLSDGTNDKIQ+VI AGVVP+LVELL H SPSV
Sbjct: 241 KPALPALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSV 300
Query: 1105 LIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRD 1284
LIPALR++GNIVTGDD QTQCVI+ GAL L LLTQNHKKSIKKEACWTISNITAGN+D
Sbjct: 301 LIPALRTVGNIVTGDDIQTQCVINSGALPCLANLLTQNHKKSIKKEACWTISNITAGNKD 360
Query: 1285 QIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDL 1464
QIQ V EA LI PLV+LLQNAEFDIKKEAAWA+SNATSGGS DQIKY+V QG +KPLCDL
Sbjct: 361 QIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATSGGSHDQIKYLVEQGCIKPLCDL 420
Query: 1465 LVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNT 1644
LVCPDPRIITVCLEGLENILKVGEAEK G+TGD N +AQLIDDAEGLEKIENLQSHDN
Sbjct: 421 LVCPDPRIITVCLEGLENILKVGEAEKNLGHTGDMNYYAQLIDDAEGLEKIENLQSHDNN 480
Query: 1645 EIYEKAVKILETYWL-EEDDET-LPPG-DESAQGFQFGGSDAAAPPGGFNF 1788
EIYEKAVKILETYWL EEDDET PPG D S GFQFGG+ A P GGFNF
Sbjct: 481 EIYEKAVKILETYWLEEEDDETQQPPGVDGSQAGFQFGGNQAPVPSGGFNF 531
>sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryza sativa subsp. japonica
GN=Os01g0253300 PE=1 SV=2
Length = 526
Score = 822 bits (2121), Expect = 4e-237
Identities = 419/524 (79%), Positives = 463/524 (88%), Gaps = 5/524 (0%)
Frame = +1
Query: 208 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQ-PTQLP 384
MSLRP+ R EVRRNRYKVAVDAEEGRRRREDNMVEIRK++ EESLLKKRREG Q +P
Sbjct: 1 MSLRPSERVEVRRNRYKVAVDAEEGRRRREDNMVEIRKSRREESLLKKRREGLQAQAPVP 60
Query: 385 QVSASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEAGVVPRF 564
+A+ V+KKLESL +M+GGV SDD +LQLEATTQFRKLLSIERSPPIEEVI++GVVPRF
Sbjct: 61 ASAATGVDKKLESLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRF 120
Query: 565 VEFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVW 744
V+FL RED+PQLQFEAAWALTNIASGTSE+TKVVI HGAVPIFV+LL S SDDVREQAVW
Sbjct: 121 VQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVW 180
Query: 745 ALGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGKPQPPFDQV 924
ALGNVAGDSP+CRDLVL+ GALLPLL+QLNEH KLSMLRNATWTLSNFCRGKPQP F+Q
Sbjct: 181 ALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQT 240
Query: 925 CPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSV 1104
PALPAL RLIHS DEEVLTDACWALSYLSDGTNDKIQ+VI AGV PRLVELL HPSPSV
Sbjct: 241 RPALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSV 300
Query: 1105 LIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRD 1284
LIPALR++GNIVTGDD+QTQC+I H AL LL LLTQN KKSIKKEACWTISNITAGN+D
Sbjct: 301 LIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKD 360
Query: 1285 QIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDL 1464
QIQAV AG+IGPLVNLLQ AEFDIKKEAAWA+SNATSGGS DQIKY+V++G +KPLCDL
Sbjct: 361 QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDL 420
Query: 1465 LVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNT 1644
L+CPD RI+TVCLEGLENILKVGE +K T GD NVF+Q+ID+AEGLEKIENLQSHDN
Sbjct: 421 LICPDIRIVTVCLEGLENILKVGETDK-TLAAGDVNVFSQMIDEAEGLEKIENLQSHDNN 479
Query: 1645 EIYEKAVKILETYWLEEDDETLPPGDESA-QG--FQFGGSDAAA 1767
EIYEKAVKILE YW++E+D+T+ +A QG F FG AA
Sbjct: 480 EIYEKAVKILEAYWMDEEDDTMGATTVAAPQGATFDFGQGGGAA 523
>sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryza sativa subsp. japonica
GN=Os05g0155500 PE=1 SV=2
Length = 534
Score = 818 bits (2112), Expect = 4e-236
Identities = 412/534 (77%), Positives = 459/534 (85%), Gaps = 8/534 (1%)
Frame = +1
Query: 208 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQ 387
MSLRP+ R EVRR+RYKVAVDA+EGRRRREDNMVEIRK++ EESLLKKRR+G
Sbjct: 1 MSLRPSERAEVRRSRYKVAVDADEGRRRREDNMVEIRKSRREESLLKKRRDGLPAAAAAA 60
Query: 388 VSA-------SSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA 546
+A S++++KLE L +MV V SDD ++QLEATTQFRKLLSIERSPPIEEVI
Sbjct: 61 AAASPLLAHSSALQQKLEGLPAMVQAVQSDDSAVQLEATTQFRKLLSIERSPPIEEVINT 120
Query: 547 GVVPRFVEFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDV 726
GVVPRF+ FL+REDYPQLQFEAAWALTNIASGTS++TKVV++ GAVPIFV+LL+S S+DV
Sbjct: 121 GVVPRFIAFLQREDYPQLQFEAAWALTNIASGTSDNTKVVVESGAVPIFVKLLSSPSEDV 180
Query: 727 REQAVWALGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGKPQ 906
REQAVWALGNVAGDSP+CRDLVL+ G L PLL QLNEHAKLSMLRNATWTLSNFCRGKPQ
Sbjct: 181 REQAVWALGNVAGDSPKCRDLVLASGGLYPLLQQLNEHAKLSMLRNATWTLSNFCRGKPQ 240
Query: 907 PPFDQVCPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQ 1086
P F+QV PAL AL+RLIHS DEEVLTDACWALSYLSDGTNDKIQ+VI +GV PRLVELL
Sbjct: 241 PNFEQVKPALSALQRLIHSQDEEVLTDACWALSYLSDGTNDKIQAVIESGVFPRLVELLM 300
Query: 1087 HPSPSVLIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNI 1266
HPS SVLIPALR++GNIVTGDD QTQCVI H AL LL LLT NHKKSIKKEACWTISNI
Sbjct: 301 HPSASVLIPALRTVGNIVTGDDMQTQCVIDHQALPCLLNLLTNNHKKSIKKEACWTISNI 360
Query: 1267 TAGNRDQIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVV 1446
TAGNR+QIQAV A +I PLV+LLQ AEFDIKKEAAWA+SNATSGG+ DQIKY+VAQG +
Sbjct: 361 TAGNREQIQAVINANIIAPLVHLLQTAEFDIKKEAAWAISNATSGGTHDQIKYLVAQGCI 420
Query: 1447 KPLCDLLVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENL 1626
KPLCDLLVCPDPRI+TVCLEGLENILKVGEAEK G GD N +AQ+IDDAEGLEKIENL
Sbjct: 421 KPLCDLLVCPDPRIVTVCLEGLENILKVGEAEKNLG-AGDVNSYAQMIDDAEGLEKIENL 479
Query: 1627 QSHDNTEIYEKAVKILETYWLEEDDETLPPGDESAQGFQFGGSDAAAPPGGFNF 1788
QSHDNTEIYEKAVK+LE+YWLEE+D+ +P GD + GF FG P GGFNF
Sbjct: 480 QSHDNTEIYEKAVKMLESYWLEEEDDAMPSGDNAQNGFNFGNQQPNVPSGGFNF 533
>sp|O22478|IMA_SOLLC Importin subunit alpha OS=Solanum lycopersicum PE=2 SV=2
Length = 527
Score = 800 bits (2065), Expect = 1e-230
Identities = 407/527 (77%), Positives = 458/527 (86%), Gaps = 5/527 (0%)
Frame = +1
Query: 208 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREG-FQPTQLP 384
MSLRPN+RTE RR+RYKVAVDAEEGRRRREDNMVEIRK K EE+LLKKRREG Q Q P
Sbjct: 1 MSLRPNSRTEARRSRYKVAVDAEEGRRRREDNMVEIRKNKREENLLKKRREGLLQAQQFP 60
Query: 385 QVSA-SSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEAGVVPR 561
+A S ++KKLE+L ++ GV SDD SLQLE TTQFRKLLSIER+PPIEEVI++GVVPR
Sbjct: 61 STAAVSHLDKKLETLPELIAGVWSDDSSLQLECTTQFRKLLSIERNPPIEEVIQSGVVPR 120
Query: 562 FVEFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAV 741
FVEFL R+DYPQLQFEAAWALTNIASGTSE+TKVVI +G+VPIF++LL+S SDDVREQAV
Sbjct: 121 FVEFLARDDYPQLQFEAAWALTNIASGTSENTKVVIDYGSVPIFIRLLSSPSDDVREQAV 180
Query: 742 WALGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGKPQPPFDQ 921
WALGN+AGDSP+ RDLVL GAL+ LL+Q NE AKLSMLRNATWTLSNFCRGKPQP F+Q
Sbjct: 181 WALGNIAGDSPKYRDLVLGHGALVALLAQFNEQAKLSMLRNATWTLSNFCRGKPQPLFEQ 240
Query: 922 VCPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPS 1101
ALP L RLIHS DEEVLTDACWALSYLSDGTNDKIQ+VI AGV RLVELL H SPS
Sbjct: 241 TKAALPTLGRLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCSRLVELLLHSSPS 300
Query: 1102 VLIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNR 1281
VLIPALR++GNIVTGDD QTQ +I H AL L+ LLTQN+KKSIKKEACWTISNITAGNR
Sbjct: 301 VLIPALRTVGNIVTGDDIQTQVMIDHHALPCLVNLLTQNYKKSIKKEACWTISNITAGNR 360
Query: 1282 DQIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCD 1461
+QIQ V EAG+I PLV LLQNAEF+IKKEAAWA+SNATSGG+ DQIK++V+QG +KPLCD
Sbjct: 361 NQIQIVIEAGIIAPLVYLLQNAEFEIKKEAAWAISNATSGGNHDQIKFLVSQGCIKPLCD 420
Query: 1462 LLVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDN 1641
LLVCPDPRI+TVCLEGLENILK+GEA+K GNT NV+AQLID+AEGLEKIENLQSHDN
Sbjct: 421 LLVCPDPRIVTVCLEGLENILKIGEADKDLGNTEGVNVYAQLIDEAEGLEKIENLQSHDN 480
Query: 1642 TEIYEKAVKILETYWLEEDDETLPPGDESAQGFQFGGSDAAAPPGGF 1782
TEIYEKAVKILETYWLEE+D + ++ F+FGG+D + P GGF
Sbjct: 481 TEIYEKAVKILETYWLEEEDVPVSLNEDQ---FEFGGADISLPSGGF 524
>sp|O04294|IMA2_ARATH Importin subunit alpha-2 OS=Arabidopsis thaliana GN=KAP2
PE=1 SV=2
Length = 531
Score = 730 bits (1883), Expect = 1e-209
Identities = 371/532 (69%), Positives = 440/532 (82%), Gaps = 7/532 (1%)
Frame = +1
Query: 208 MSLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGF----QPT 375
MSLRP+A+TEVRRNRYKVAVDAEEGRRRREDN+VEIRK K EE+L KKR T
Sbjct: 1 MSLRPSAKTEVRRNRYKVAVDAEEGRRRREDNLVEIRKNKREENLQKKRFTSSMAFGSAT 60
Query: 376 QLPQVSASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEAGVV 555
+ SS + ++L +MV G+ S+D + QLEAT RKLLSIE++PPI EV+++GVV
Sbjct: 61 GQTEQDLSSANQLKDNLPAMVAGIWSEDSNSQLEATNLLRKLLSIEQNPPINEVVQSGVV 120
Query: 556 PRFVEFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQ 735
PR V+FL R+D+P+LQFEAAWALTNIASGTSE+T V+I+ GAVPIF+QLL+S S+DVREQ
Sbjct: 121 PRVVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQ 180
Query: 736 AVWALGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGKPQPPF 915
AVWALGNVAGDSP+CRDLVLS GA+ PLLSQ NE+ KLSMLRNATWTLSNFCRGKP P F
Sbjct: 181 AVWALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGKPPPAF 240
Query: 916 DQVCPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPS 1095
+Q PALP LERL+ S DEEVLTDACWALSYLSD +NDKIQ+VI AGVVPRL++LL H S
Sbjct: 241 EQTQPALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSS 300
Query: 1096 PSVLIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAG 1275
PSVLIPALR+IGNIVTGDD QTQ V+ AL LL LL N+KKSIKKEACWTISNITAG
Sbjct: 301 PSVLIPALRTIGNIVTGDDLQTQMVLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAG 360
Query: 1276 NRDQIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPL 1455
N DQIQAV +AG+I LV +LQ+AEF++KKEAAW +SNATSGG+ DQIK+MV+QG +KPL
Sbjct: 361 NADQIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNATSGGTHDQIKFMVSQGCIKPL 420
Query: 1456 CDLLVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSH 1635
CDLL CPD +++TVCLE LENIL VGEAEK G+TG+ N++AQ+ID+AEGLEKIENLQSH
Sbjct: 421 CDLLTCPDLKVVTVCLEALENILVVGEAEKNLGHTGEDNLYAQMIDEAEGLEKIENLQSH 480
Query: 1636 DNTEIYEKAVKILETYWLEEDDETLPPGDESAQ-GFQFGGSDAAAPPGGFNF 1788
DN +IY+KAVKILET+W E+++E + + Q GFQFG ++ PPG FNF
Sbjct: 481 DNNDIYDKAVKILETFWTEDNEEEGNDENHAPQSGFQFGSTN--VPPGQFNF 530
>sp|Q76P29|IMAB_DICDI Importin subunit alpha-B OS=Dictyostelium discoideum
GN=DDB_G0272318 PE=3 SV=1
Length = 516
Score = 560 bits (1442), Expect = 2e-158
Identities = 302/514 (58%), Positives = 385/514 (74%), Gaps = 12/514 (2%)
Frame = +1
Query: 226 ARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQVSASSV 405
++ E R+++YK ++D++E RR+RE+ + IRK K EESLLKKR + P P S +
Sbjct: 4 SKQETRKSQYKKSIDSDESRRKREEASLSIRKNKREESLLKKRTQAV-PGSTPVKVDSLI 62
Query: 406 EKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEAGVVPRFVEFLKRE 585
++LE L S+V + S++ L L++TT FRKLLSIE+SPPIEEVI+ G+VPR V+FL +
Sbjct: 63 NQRLEQLPSLVAEINSENPDLILKSTTAFRKLLSIEKSPPIEEVIKTGIVPRLVKFLYMQ 122
Query: 586 DYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNVAG 765
D+PQLQFEAAWALTNIASGT E T+VVI++GA+ +FV LL+S DDVREQAVWALGN+AG
Sbjct: 123 DFPQLQFEAAWALTNIASGTPEQTRVVIENGAIQVFVLLLSSPHDDVREQAVWALGNIAG 182
Query: 766 DSPQCRDLVLSQGALLPLLSQLNEHA--KLSMLRNATWTLSNFCRGKPQPPFDQVCPALP 939
DS CRDLVLS AL PLLS L A K+SM+RNATWTLSNFCRGKPQPPF+ V +LP
Sbjct: 183 DSHYCRDLVLSHNALPPLLSLLQNPAAIKVSMVRNATWTLSNFCRGKPQPPFEIVRASLP 242
Query: 940 ALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPAL 1119
L +LI+ DEEVL DACWALSYLSDG+N++IQ VI A V ++VELL HP+ +V PAL
Sbjct: 243 VLAKLIYYQDEEVLIDACWALSYLSDGSNERIQEVIDAKVCRKMVELLGHPTIAVQTPAL 302
Query: 1120 RSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQAV 1299
R+IGNIVTGDD+QTQ V+S AL LL LL Q+ K++I+KEACWTISNITAG+++QIQ V
Sbjct: 303 RTIGNIVTGDDNQTQIVLSVQALSHLLNLL-QSPKRAIRKEACWTISNITAGDKNQIQQV 361
Query: 1300 CEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCPD 1479
+A +I LV LL NAEF+I+KEAAWA+SNATS G+ QI ++V+QG VKPLCDLL D
Sbjct: 362 IDANIIPSLVYLLANAEFEIQKEAAWAISNATSCGTPQQIHFLVSQGCVKPLCDLLKVSD 421
Query: 1480 PRIITVCLEGLENILKVGEAE-KVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYE 1656
PRII V LEG+ENIL G+ E +VTG N + ++I+DA+GL KI +LQ H N + +E
Sbjct: 422 PRIINVALEGIENILVAGKKEAQVTG----VNPYKKIIEDADGLGKIYDLQHHMNKDTFE 477
Query: 1657 KAVKILETYWLEEDDETLPPGDESAQGFQFGGSD 1758
K +I+ TY +DE GD +G F S+
Sbjct: 478 KVSRIISTYL---EDEQEDEGDLMPEGSSFSFSN 508
>sp|O35345|IMA7_MOUSE Importin subunit alpha-7 OS=Mus musculus GN=Kpna6 PE=1
SV=2
Length = 536
Score = 512 bits (1318), Expect = 5e-144
Identities = 283/518 (54%), Positives = 362/518 (69%), Gaps = 15/518 (2%)
Frame = +1
Query: 262 AVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQVSASSVEKKLESLS---- 429
A++ EE RRRRE+ +++RK K E+ L K+R + + ++ + S +
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 430 ---SMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFVEFLKREDYPQ 597
MV + SDD LQL T +FRKLLS E SPPI+EVI GVV RFVEFLKR +
Sbjct: 81 ITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRNENCT 140
Query: 598 LQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNVAGDSPQ 777
LQFEAAWALTNIASGTS+ TK+VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSL 200
Query: 778 CRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPALPALERL 954
CRD VL+ L PLL+ L + +L+M RNA W LSN CRGK P P F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 955 IHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPALRSIGN 1134
+ S+D ++L DACWALSYLSDG N+KIQ+VI +GV RLVELL H V PALR++GN
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGN 320
Query: 1135 IVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQAVCEAGL 1314
IVTGDD QTQ +++ AL LL LL+ + K+SI+KEACWTISNITAGNR QIQAV +A +
Sbjct: 321 IVTGDDIQTQVILNCSALPCLLHLLSSS-KESIRKEACWTISNITAGNRAQIQAVIDANI 379
Query: 1315 IGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCPDPRIIT 1494
L+ +LQ AEF +KEAAWA++NATSGG+ +QI+Y+V+ G +KPLCDLL D +I+
Sbjct: 380 FPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQ 439
Query: 1495 VCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYEKAVKIL 1674
V L GLENIL++GE E +G N + LI++A GL+KIE LQSH+N EIY+KA ++
Sbjct: 440 VALNGLENILRLGEQESKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLI 498
Query: 1675 ETYW-LEEDDETLPPG-DESAQGFQFGGSDAAAPPGGF 1782
E Y+ +E+DD +L P DE+ Q F F AP GF
Sbjct: 499 EHYFGVEDDDSSLAPQVDETQQQFIF--QQPEAPMEGF 534
>sp|Q0V7M0|IMA7_BOVIN Importin subunit alpha-7 OS=Bos taurus GN=KPNA6 PE=2 SV=1
Length = 536
Score = 512 bits (1316), Expect = 8e-144
Identities = 283/518 (54%), Positives = 362/518 (69%), Gaps = 15/518 (2%)
Frame = +1
Query: 262 AVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQVSASSVEKKLESLS---- 429
A++ EE RRRRE+ +++RK K E+ L K+R + + ++ + S +
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 430 ---SMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFVEFLKREDYPQ 597
MV + SDD LQL T +FRKLLS E SPPI+EVI GVV RFVEFLKR +
Sbjct: 81 ITREMVEMLFSDDPDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRNENCT 140
Query: 598 LQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNVAGDSPQ 777
LQFEAAWALTNIASGTS+ TK+VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 778 CRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPALPALERL 954
CRD VL+ L PLL+ L + +L+M RNA W LSN CRGK P P F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 955 IHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPALRSIGN 1134
+ S+D ++L DACWALSYLSDG N+KIQ+VI +GV RLVELL H V PALR++GN
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDNKVASPALRAVGN 320
Query: 1135 IVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQAVCEAGL 1314
IVTGDD QTQ +++ AL LL LL+ + K+SI+KEACWTISNITAGNR QIQAV +A +
Sbjct: 321 IVTGDDIQTQVILNCSALPCLLHLLSSS-KESIRKEACWTISNITAGNRAQIQAVIDANI 379
Query: 1315 IGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCPDPRIIT 1494
L+ +LQ AEF +KEAAWA++NATSGG+ +QI+Y+V+ G +KPLCDLL D +I+
Sbjct: 380 FPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQ 439
Query: 1495 VCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYEKAVKIL 1674
V L GLENIL++GE E +G N + LI++A GL+KIE LQSH+N EIY+KA ++
Sbjct: 440 VALNGLENILRLGEQEGKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLI 498
Query: 1675 ETYW-LEEDDETLPPG-DESAQGFQFGGSDAAAPPGGF 1782
E Y+ +E+DD +L P DE+ Q F F AP GF
Sbjct: 499 EHYFGVEDDDSSLAPQVDETQQQFIF--QQPEAPMEGF 534
>sp|O60684|IMA7_HUMAN Importin subunit alpha-7 OS=Homo sapiens GN=KPNA6 PE=1
SV=1
Length = 536
Score = 508 bits (1306), Expect = 1e-142
Identities = 282/518 (54%), Positives = 361/518 (69%), Gaps = 15/518 (2%)
Frame = +1
Query: 262 AVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQVSASSVEKKLESLS---- 429
A++ EE RRRRE+ +++RK K E+ L K+R + + ++ + S +
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 430 ---SMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFVEFLKREDYPQ 597
MV + SDD LQL T +FRKLLS E SPPI+EVI VV RFVEFLKR +
Sbjct: 81 ITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCT 140
Query: 598 LQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNVAGDSPQ 777
LQFEAAWALTNIASGTS+ TK+VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 778 CRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPALPALERL 954
CRD VL+ L PLL+ L + +L+M RNA W LSN CRGK P P F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 955 IHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPALRSIGN 1134
+ S+D ++L DACWALSYLSDG N+KIQ+VI +GV RLVELL H V PALR++GN
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGN 320
Query: 1135 IVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQAVCEAGL 1314
IVTGDD QTQ +++ AL LL LL+ + K+SI+KEACWTISNITAGNR QIQAV +A +
Sbjct: 321 IVTGDDIQTQVILNCSALPCLLHLLS-SPKESIRKEACWTISNITAGNRAQIQAVIDANI 379
Query: 1315 IGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCPDPRIIT 1494
L+ +LQ AEF +KEAAWA++NATSGG+ +QI+Y+V+ G +KPLCDLL D +I+
Sbjct: 380 FPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQ 439
Query: 1495 VCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYEKAVKIL 1674
V L GLENIL++GE E +G N + LI++A GL+KIE LQSH+N EIY+KA ++
Sbjct: 440 VALNGLENILRLGEQEGKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLI 498
Query: 1675 ETYW-LEEDDETLPPG-DESAQGFQFGGSDAAAPPGGF 1782
E Y+ +E+DD +L P DE+ Q F F AP GF
Sbjct: 499 EHYFGVEDDDSSLAPQVDETQQQFIF--QQPEAPMEGF 534
>sp|Q5RBV0|IMA7_PONAB Importin subunit alpha-7 OS=Pongo abelii GN=KPNA6 PE=2
SV=1
Length = 536
Score = 508 bits (1306), Expect = 1e-142
Identities = 282/518 (54%), Positives = 361/518 (69%), Gaps = 15/518 (2%)
Frame = +1
Query: 262 AVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQVSASSVEKKLESLS---- 429
A++ EE RRRRE+ +++RK K E+ L K+R + + ++ + S +
Sbjct: 21 ALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESV 80
Query: 430 ---SMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFVEFLKREDYPQ 597
MV + SDD LQL T +FRKLLS E SPPI+EVI VV RFVEFLKR +
Sbjct: 81 ITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCT 140
Query: 598 LQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNVAGDSPQ 777
LQFEAAWALTNIASGTS+ TK+VI+ GAVPIF++LL S +DV+EQAVWALGN+AGDS
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 778 CRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPALPALERL 954
CRD VL+ L PLL+ L + +L+M RNA W LSN CRGK P P F +V P LP L RL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRL 260
Query: 955 IHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPALRSIGN 1134
+ S+D ++L DACWALSYLSDG N+KIQ+VI +GV RLVELL H V PALR++GN
Sbjct: 261 LFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGN 320
Query: 1135 IVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQAVCEAGL 1314
IVTGDD QTQ +++ AL LL LL+ + K+SI+KEACWTISNITAGNR QIQAV +A +
Sbjct: 321 IVTGDDIQTQVILNCSALPCLLHLLS-SPKESIRKEACWTISNITAGNRAQIQAVIDANI 379
Query: 1315 IGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCPDPRIIT 1494
L+ +LQ AEF +KEAAWA++NATSGG+ +QI+Y+V+ G +KPLCDLL D +I+
Sbjct: 380 FPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQ 439
Query: 1495 VCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYEKAVKIL 1674
V L GLENIL++GE E +G N + LI++A GL+KIE LQSH+N EIY+KA ++
Sbjct: 440 VALNGLENILRLGEQEGKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLI 498
Query: 1675 ETYW-LEEDDETLPPG-DESAQGFQFGGSDAAAPPGGF 1782
E Y+ +E+DD +L P DE+ Q F F AP GF
Sbjct: 499 EHYFGVEDDDSSLAPQVDETQQQFIF--QQPEAPMEGF 534
>sp|Q5ZML1|IMA1_CHICK Importin subunit alpha-1 OS=Gallus gallus GN=KPNA1 PE=2
SV=1
Length = 538
Score = 486 bits (1249), Expect = 5e-136
Identities = 278/531 (52%), Positives = 355/531 (66%), Gaps = 19/531 (3%)
Frame = +1
Query: 211 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKR---REGFQPTQL 381
SL P+ E+RR R + + +++RE+ + + R E ++ GF Q+
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAEEEAEEEVMSDGGFHEAQM 72
Query: 382 PQVSASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVP 558
+ +S S M+ + S+ QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 73 NNMEMTS---SAVITSDMIEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 559 RFVEFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQA 738
RFVEFLKR++ LQFEAAW LTNIASG S T++VIQ GAVPIF++LL+S+ +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFEAAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 739 VWALGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPF 915
VWALGN+AGDS CRD VL L PLL L++ +++M RNA W LSN CRGK P P F
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLLSKQNRITMTRNAVWALSNLCRGKNPPPDF 249
Query: 916 DQVCPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPS 1095
+V P L L L+ D +VL DACWALSYLSDG NDKIQ+VI AGV RLVELL H
Sbjct: 250 AKVSPCLSVLSWLLFVNDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 1096 PSVLIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAG 1275
V+ PALR++GNIVTGDD QTQ +++ AL SLL LL+ + K+SIKKEACWTISNITAG
Sbjct: 310 YKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS-SPKESIKKEACWTISNITAG 368
Query: 1276 NRDQIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPL 1455
NR QIQ V +A + L+N+LQ AEF +KEAAWA++NATSGGSA+QIKY+V G +KPL
Sbjct: 369 NRAQIQTVIDAHIFPALINILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPL 428
Query: 1456 CDLLVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSH 1635
CDLL D +I+ V L GLENIL++GE E G N + LI++A GL+KIE LQSH
Sbjct: 429 CDLLTVMDSKIVQVALSGLENILRLGEQESKRSGAG-INPYCALIEEAYGLDKIEFLQSH 487
Query: 1636 DNTEIYEKAVKILETYWLEEDDET--LPPGDESAQGFQFGGSDAAAPPGGF 1782
+N EIY+KA ++E Y+ ED+++ P D S Q + F AP GF
Sbjct: 488 ENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIF--QQCEAPMEGF 536
>sp|Q503E9|IMA5_DANRE Importin subunit alpha-6 OS=Danio rerio GN=kpna5 PE=2
SV=2
Length = 536
Score = 482 bits (1239), Expect = 7e-135
Identities = 272/523 (52%), Positives = 360/523 (68%), Gaps = 18/523 (3%)
Frame = +1
Query: 235 EVRRNRYKVAVDAEEGRRRREDNMVEIRKTKC---EESLLKKRREGFQPTQLPQVSAS-S 402
E+RR R + + +++RE+ + + R +ES+L+ P Q P VS++
Sbjct: 23 EMRRRREEEGIQLR--KQKREEQLFKRRNVSLPPGDESMLE------CPIQDPDVSSTVP 74
Query: 403 VEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVI-EAGVVPRFVEFLK 579
V + ++ + S+D QL AT +FRKLLS E +PPI+EVI GVV RFVEFL+
Sbjct: 75 VSGEGVITQDVIQMIFSEDPDQQLIATQKFRKLLSKEPNPPIDEVIGTPGVVNRFVEFLR 134
Query: 580 REDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNV 759
R D LQFEAAWALTNIASGT +HTKVVI+ GAVPIF++LL S+ +DV+EQAVWALGN+
Sbjct: 135 RSDNCTLQFEAAWALTNIASGTFQHTKVVIETGAVPIFIELLNSEYEDVQEQAVWALGNI 194
Query: 760 AGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPAL 936
AGD+ +CRD VL+ G L L L + +L+ RNA W LSN CRGK P P F +V P L
Sbjct: 195 AGDNAECRDYVLNCGILPSLQQLLAKSNRLTTTRNAVWALSNLCRGKNPPPDFAKVSPCL 254
Query: 937 PALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPA 1116
L RL+ S+D +VL DACWALSYLSDG NDKIQ+VI +GV RLVELL H V+ PA
Sbjct: 255 SVLSRLLFSSDPDVLADACWALSYLSDGPNDKIQTVIDSGVCRRLVELLMHSDYKVVSPA 314
Query: 1117 LRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQA 1296
LR++GNIVTGDD QTQ +++ AL LL LL+ + K+SIKKEACWT+SNITAGNR QIQA
Sbjct: 315 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLS-SPKESIKKEACWTVSNITAGNRAQIQA 373
Query: 1297 VCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCP 1476
V ++ + L+ +LQ AEF +KEAAWA++NATSGG+ +QI+Y+V+ +KP+CDLL
Sbjct: 374 VIDSNVFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLNTIKPMCDLLTVM 433
Query: 1477 DPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYE 1656
D +I+ V L GLENIL++GE E TG N + LI++A GL+KIE LQSH+N EIY+
Sbjct: 434 DSKIVQVALNGLENILRLGEQESKQNGTG-INPYCALIEEAYGLDKIEFLQSHENQEIYQ 492
Query: 1657 KAVKILETYW-LEEDDETLPPGDESAQGFQFGGSDAAAPPGGF 1782
KA ++E Y+ +EE+D ++ P + QG Q+ + P GF
Sbjct: 493 KAFDLIEHYFGVEEEDASIVPQVDQNQG-QYIFQQSEGPMEGF 534
>sp|A2VE08|IMA1_BOVIN Importin subunit alpha-1 OS=Bos taurus GN=KPNA1 PE=2 SV=1
Length = 538
Score = 481 bits (1238), Expect = 9e-135
Identities = 274/528 (51%), Positives = 353/528 (66%), Gaps = 13/528 (2%)
Frame = +1
Query: 211 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQV 390
SL P+ E+RR R + + +++RE+ + + R E ++ Q+
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQI 72
Query: 391 SASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFV 567
+ + S M+ + S+ QL AT +FRKLLS E +PPI+EVI GVV RFV
Sbjct: 73 NNMEMAPGGVITSDMIEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFV 132
Query: 568 EFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWA 747
EFLKR++ LQFE+AW LTNIASG S T++VIQ GAVPIF++LL+S+ +DV+EQAVWA
Sbjct: 133 EFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWA 192
Query: 748 LGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQV 924
LGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P F +V
Sbjct: 193 LGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKV 252
Query: 925 CPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSV 1104
P L L L+ +D +VL DACWALSYLSDG NDKIQ+VI AGV RLVELL H V
Sbjct: 253 SPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKV 312
Query: 1105 LIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRD 1284
+ PALR++GNIVTGDD QTQ +++ AL SLL LL+ + K+SIKKEACWTISNITAGNR
Sbjct: 313 VSPALRAVGNIVTGDDVQTQVILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRA 371
Query: 1285 QIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDL 1464
QIQ V +A + L+++LQ AEF +KEAAWA++NATSGGSA+QIKY+V G +KPLCDL
Sbjct: 372 QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 1465 LVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNT 1644
L D +I+ V L GLENIL++GE E TG N + LI++A GL+KIE LQSH+N
Sbjct: 432 LTVMDSKIVQVALNGLENILRLGEQEAKRNGTG-INPYCALIEEAYGLDKIEFLQSHENQ 490
Query: 1645 EIYEKAVKILETYWLEEDDET--LPPGDESAQGFQFGGSDAAAPPGGF 1782
EIY+KA ++E Y+ ED+++ P D S Q + F AP GF
Sbjct: 491 EIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIF--QQCEAPMEGF 536
>sp|P52294|IMA1_HUMAN Importin subunit alpha-1 OS=Homo sapiens GN=KPNA1 PE=1
SV=3
Length = 538
Score = 481 bits (1236), Expect = 1e-134
Identities = 274/528 (51%), Positives = 352/528 (66%), Gaps = 13/528 (2%)
Frame = +1
Query: 211 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQV 390
SL P+ E+RR R + + +++RE+ + + R E ++ Q+
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQI 72
Query: 391 SASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFV 567
S + S M+ + S QL AT +FRKLLS E +PPI+EVI GVV RFV
Sbjct: 73 SNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFV 132
Query: 568 EFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWA 747
EFLKR++ LQFE+AW LTNIASG S T++VIQ GAVPIF++LL+S+ +DV+EQAVWA
Sbjct: 133 EFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWA 192
Query: 748 LGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQV 924
LGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P F +V
Sbjct: 193 LGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKV 252
Query: 925 CPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSV 1104
P L L L+ +D +VL DACWALSYLSDG NDKIQ+VI AGV RLVELL H V
Sbjct: 253 SPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKV 312
Query: 1105 LIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRD 1284
+ PALR++GNIVTGDD QTQ +++ AL SLL LL+ + K+SIKKEACWTISNITAGNR
Sbjct: 313 VSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRA 371
Query: 1285 QIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDL 1464
QIQ V +A + L+++LQ AEF +KEAAWA++NATSGGSA+QIKY+V G +KPLCDL
Sbjct: 372 QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 1465 LVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNT 1644
L D +I+ V L GLENIL++GE E TG N + LI++A GL+KIE LQSH+N
Sbjct: 432 LTVMDSKIVQVALNGLENILRLGEQEAKRNGTG-INPYCALIEEAYGLDKIEFLQSHENQ 490
Query: 1645 EIYEKAVKILETYWLEEDDET--LPPGDESAQGFQFGGSDAAAPPGGF 1782
EIY+KA ++E Y+ ED+++ P D + Q + F AP GF
Sbjct: 491 EIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIF--QQCEAPMEGF 536
>sp|Q5R909|IMA1_PONAB Importin subunit alpha-1 OS=Pongo abelii GN=KPNA1 PE=2
SV=1
Length = 538
Score = 480 bits (1233), Expect = 3e-134
Identities = 273/528 (51%), Positives = 352/528 (66%), Gaps = 13/528 (2%)
Frame = +1
Query: 211 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQV 390
SL P+ E+RR R + + +++RE+ + + R E ++ Q+
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQI 72
Query: 391 SASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFV 567
+ + S M+ + S QL AT +FRKLLS E +PPI+EVI GVV RFV
Sbjct: 73 NNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFV 132
Query: 568 EFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWA 747
EFLKR++ LQFE+AW LTNIASG S T++VIQ GAVPIF++LL+S+ +DV+EQAVWA
Sbjct: 133 EFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWA 192
Query: 748 LGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQV 924
LGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P F +V
Sbjct: 193 LGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKV 252
Query: 925 CPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSV 1104
P L L L+ +D +VL DACWALSYLSDG NDKIQ+VI AGV RLVELL H V
Sbjct: 253 SPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKV 312
Query: 1105 LIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRD 1284
+ PALR++GNIVTGDD QTQ +++ AL SLL LL+ + K+SIKKEACWTISNITAGNR
Sbjct: 313 VSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRA 371
Query: 1285 QIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDL 1464
QIQ V +A + L+++LQ AEF +KEAAWA++NATSGGSA+QIKY+V G +KPLCDL
Sbjct: 372 QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 1465 LVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNT 1644
L D +I+ V L GLENIL++GE E TG N + LI++A GL+KIE LQSH+N
Sbjct: 432 LTVMDSKIVQVALNGLENILRLGEQEAKRNGTG-INPYCALIEEAYGLDKIEFLQSHENQ 490
Query: 1645 EIYEKAVKILETYWLEEDDET--LPPGDESAQGFQFGGSDAAAPPGGF 1782
EIY+KA ++E Y+ ED+++ P D + Q + F AP GF
Sbjct: 491 EIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIF--QQCEAPMEGF 536
>sp|P83953|IMA1_RAT Importin subunit alpha-1 OS=Rattus norvegicus GN=Kpna1 PE=2
SV=1
Length = 538
Score = 478 bits (1228), Expect = 1e-133
Identities = 271/524 (51%), Positives = 353/524 (67%), Gaps = 17/524 (3%)
Frame = +1
Query: 211 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKR---REGFQPTQL 381
SL P+ E+RR R + + +++RE+ + + R E ++ GF Q+
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQI 72
Query: 382 PQVSASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVP 558
+ + ++ M + S+ QL AT +FRKLLS E +PPI+EVI GVV
Sbjct: 73 NNMEMAPGGVITSDMTEM---IFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVA 129
Query: 559 RFVEFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQA 738
RFVEFLKR++ LQFE+AW LTNIASG S T++VIQ GAVPIF++LL+S+ +DV+EQA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 739 VWALGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPF 915
VWALGN+AGDS CRD VL L PLL ++ +L+M RNA W LSN CRGK P P F
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 916 DQVCPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPS 1095
+V P L L L+ +D +VL DACWALSYLSDG NDKIQ+VI AGV RLVELL H
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHND 309
Query: 1096 PSVLIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAG 1275
V+ PALR++GNIVTGDD QTQ +++ AL SLL LL+ + K+SIKKEACWTISNITAG
Sbjct: 310 YKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS-SPKESIKKEACWTISNITAG 368
Query: 1276 NRDQIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPL 1455
NR QIQ V +A + L+++LQ AEF +KEAAWA++NATSGGSA+QIKY+V G +KPL
Sbjct: 369 NRAQIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPL 428
Query: 1456 CDLLVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSH 1635
CDLL D +I+ V L GLENIL++GE E +G N + LI++A GL+KIE LQSH
Sbjct: 429 CDLLTVMDAKIVQVALNGLENILRLGEQEAKRNGSG-INPYCALIEEAYGLDKIEFLQSH 487
Query: 1636 DNTEIYEKAVKILETYWLEEDDET--LPPGDESAQGFQFGGSDA 1761
+N EIY+KA ++E Y+ ED+++ P D S Q + F +A
Sbjct: 488 ENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEA 531
>sp|Q60960|IMA1_MOUSE Importin subunit alpha-1 OS=Mus musculus GN=Kpna1 PE=1
SV=2
Length = 538
Score = 477 bits (1227), Expect = 2e-133
Identities = 273/528 (51%), Positives = 352/528 (66%), Gaps = 13/528 (2%)
Frame = +1
Query: 211 SLRPNARTEVRRNRYKVAVDAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQV 390
SL P+ E+RR R + + +++RE+ + + R E ++ Q+
Sbjct: 18 SLNPD---EMRRRREEEGLQLR--KQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQI 72
Query: 391 SASSVEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIEA-GVVPRFV 567
+ + S M + S+ QL AT +FRKLLS E +PPI+EVI GVV RFV
Sbjct: 73 NNMEMAPGGVITSDMTDMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVINTPGVVARFV 132
Query: 568 EFLKREDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWA 747
EFLKR++ LQFE+AW LTNIASG S T+ VIQ GAVPIF++LL+S+ +DV+EQAVWA
Sbjct: 133 EFLKRKENCTLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWA 192
Query: 748 LGNVAGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQV 924
LGN+AGDS CRD VL+ L PLL ++ +L+M RNA W LSN CRGK P P F +V
Sbjct: 193 LGNIAGDSTMCRDYVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKV 252
Query: 925 CPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSV 1104
P L L L+ +D +VL DACWALSYLSDG NDKIQ+VI AGV RLVELL H V
Sbjct: 253 SPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKV 312
Query: 1105 LIPALRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRD 1284
+ PALR++GNIVTGDD QTQ +++ AL SLL LL+ + K+SIKKEACWTISNITAGNR
Sbjct: 313 VSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRA 371
Query: 1285 QIQAVCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDL 1464
QIQ V +A + L+++LQ AEF +KEAAWA++NATSGGSA+QIKY+V G +KPLCDL
Sbjct: 372 QIQTVIDANMFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 1465 LVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNT 1644
L D +I+ V L GLENIL++GE E +G N + LI++A GL+KIE LQSH+N
Sbjct: 432 LTVMDAKIVQVALNGLENILRLGEQEAKRNGSG-INPYCALIEEAYGLDKIEFLQSHENQ 490
Query: 1645 EIYEKAVKILETYWLEEDDET--LPPGDESAQGFQFGGSDAAAPPGGF 1782
EIY+KA ++E Y+ ED+++ P D S Q + F AP GF
Sbjct: 491 EIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIF--QQCEAPMEGF 536
>sp|Q56R16|IMA5_RAT Importin subunit alpha-6 OS=Rattus norvegicus GN=Kpna5 PE=2
SV=1
Length = 536
Score = 477 bits (1226), Expect = 2e-133
Identities = 270/524 (51%), Positives = 357/524 (68%), Gaps = 20/524 (3%)
Frame = +1
Query: 235 EVRRNRYKVAVDAEEGRRRREDNMVEIRKT---KCEESLLKKRREGFQPTQLPQVSAS-S 402
E+RR R + + +++RE+ + + R + ++ +L+ P Q P VS++
Sbjct: 23 EMRRRREEEGIQLR--KQKREEQLFKRRNVSLPRNDDCMLE------SPIQDPDVSSTVP 74
Query: 403 VEKKLESLSSMVGGVLSDDRSLQLEATTQFRKLLSIERSPPIEEVIE-AGVVPRFVEFLK 579
+ ++ + M+ + S++ QL AT +FRKLLS E +PPI++VI+ GVV RFV+FL+
Sbjct: 75 IPEEDMITADMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLE 134
Query: 580 REDYPQLQFEAAWALTNIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNV 759
R + LQFEAAWALTNIASGT HTKVVI+ GAVPIF++LL S+ +DV+EQAVWALGN+
Sbjct: 135 RNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNI 194
Query: 760 AGDSPQCRDLVLSQGALLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPAL 936
AGD+ +CRD VL+ L PLL L +L+ RNA W LSN CRGK P P F +V P L
Sbjct: 195 AGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCL 254
Query: 937 PALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPA 1116
L RL+ S+D +VL D CWALSYLSDG NDKIQ VI +GV RLVELL H V+ PA
Sbjct: 255 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPA 314
Query: 1117 LRSIGNIVTGDDSQTQCVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQA 1296
LR++GNIVTGDD QTQ +++ AL LL LL + K+S++KEACWTISNITAGNR QIQA
Sbjct: 315 LRAVGNIVTGDDIQTQVILNCSALPCLLHLL-GSPKESVRKEACWTISNITAGNRMQIQA 373
Query: 1297 VCEAGLIGPLVNLLQNAEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCP 1476
V + + L+ +LQ AEF +KEAAWA++NATSGG+ +QI+Y+V G +KPLCDLL
Sbjct: 374 VIDGSIFPVLIEVLQKAEFRTRKEAAWAITNATSGGAPEQIRYLVTLGCIKPLCDLLTVM 433
Query: 1477 DPRIITVCLEGLENILKVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYE 1656
D +I+ V L GLENIL++GE E G N + LI++A GL+KIE LQSH+N EIY+
Sbjct: 434 DSKIVQVALNGLENILRLGERESKQNGVG-INPYCALIEEAYGLDKIEFLQSHENQEIYQ 492
Query: 1657 KAVKILETYW-LEEDDETL-PPGDESAQGFQFGGSDAAAPPGGF 1782
KA ++E Y+ +EEDD +L P DE + F F AP GF
Sbjct: 493 KAFDLIERYFGVEEDDPSLVPQVDEQQRQFLF--QQCEAPGEGF 534
>sp|O00629|IMA4_HUMAN Importin subunit alpha-4 OS=Homo sapiens GN=KPNA4 PE=1
SV=1
Length = 521
Score = 432 bits (1110), Expect = 6e-120
Identities = 234/503 (46%), Positives = 323/503 (64%), Gaps = 15/503 (2%)
Frame = +1
Query: 268 DAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQVSASSVEKKLESLSSMVGGV 447
D E RR+R + +VE+RK K +E LLK+R + + SL ++V
Sbjct: 21 DLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNA 80
Query: 448 LSDDRSLQLEATTQFRKLLSIERSPPIEEVIEAGVVPRFVEFLKREDYPQLQFEAAWALT 627
SD++ +QL A RKLLS +R+PPI+++I++G++P V L+R+D P LQFEAAWALT
Sbjct: 81 SSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALT 140
Query: 628 NIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNVAGDSPQCRDLVLSQGA 807
NIASGTSE T+ V+Q AVP+F++LL S +V EQAVWALGN+ GD PQCRD V+S G
Sbjct: 141 NIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGV 200
Query: 808 LLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPALPALERLIHSTDEEVLT 984
+ PLLS ++ ++ LRN TW + N CR K P PP + + LPAL LIH TD +L
Sbjct: 201 VKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILV 260
Query: 985 DACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPALRSIGNIVTGDDSQTQ 1164
D WALSYL+D N++IQ VI +G+VP LV LL H V ALR++GNIVTG D QTQ
Sbjct: 261 DTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQ 320
Query: 1165 CVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQAVCEAGLIGPLVNLLQN 1344
V++ AL LLT + K+ I KEA W +SNITAGN+ Q+QAV +A L+ +++LL
Sbjct: 321 VVLNCDALSHFPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDK 379
Query: 1345 AEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCPDPRIITVCLEGLENIL 1524
+F +KEAAWA+SN T G DQ+ Y++ Q V+ P C+LL D +++ V L+GL NIL
Sbjct: 380 GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNIL 439
Query: 1525 KVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYEKAVKILETYWLEED-- 1698
K+ E E A LI++ GLEKIE LQ+H+N +IY+ A +I++ ++ +D
Sbjct: 440 KMAEDE--------AETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDID 491
Query: 1699 -DETLPPGDESAQGFQFGGSDAA 1764
D +L P E+ QG FG + +A
Sbjct: 492 EDPSLVP--EAIQGGTFGFNSSA 512
>sp|O35343|IMA4_MOUSE Importin subunit alpha-4 OS=Mus musculus GN=Kpna4 PE=2
SV=1
Length = 521
Score = 432 bits (1110), Expect = 6e-120
Identities = 234/498 (46%), Positives = 321/498 (64%), Gaps = 15/498 (3%)
Frame = +1
Query: 268 DAEEGRRRREDNMVEIRKTKCEESLLKKRREGFQPTQLPQVSASSVEKKLESLSSMVGGV 447
D E RR+R + +VE+RK K +E LLK+R + + SL ++V
Sbjct: 21 DLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNA 80
Query: 448 LSDDRSLQLEATTQFRKLLSIERSPPIEEVIEAGVVPRFVEFLKREDYPQLQFEAAWALT 627
SD++ +QL A RKLLS +R+PPI+++I++G++P V L+R+D P LQFEAAWALT
Sbjct: 81 SSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALT 140
Query: 628 NIASGTSEHTKVVIQHGAVPIFVQLLASQSDDVREQAVWALGNVAGDSPQCRDLVLSQGA 807
NIASGTSE T+ V+Q AVP+F++LL S +V EQAVWALGN+ GD PQCRD V+S G
Sbjct: 141 NIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGV 200
Query: 808 LLPLLSQLNEHAKLSMLRNATWTLSNFCRGK-PQPPFDQVCPALPALERLIHSTDEEVLT 984
+ PLLS ++ ++ LRN TW + N CR K P PP + + LPAL LIH TD +L
Sbjct: 201 VKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILV 260
Query: 985 DACWALSYLSDGTNDKIQSVIMAGVVPRLVELLQHPSPSVLIPALRSIGNIVTGDDSQTQ 1164
D WALSYL+D N++IQ VI +G+VP LV LL H V ALR++GNIVTG D QTQ
Sbjct: 261 DTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQ 320
Query: 1165 CVISHGALLSLLGLLTQNHKKSIKKEACWTISNITAGNRDQIQAVCEAGLIGPLVNLLQN 1344
V++ AL LLT + K+ I KEA W +SNITAGN+ Q+QAV +A L+ +++LL
Sbjct: 321 VVLNCDALSHFPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDK 379
Query: 1345 AEFDIKKEAAWAVSNATSGGSADQIKYMVAQGVVKPLCDLLVCPDPRIITVCLEGLENIL 1524
+F +KEAAWA+SN T G DQ+ Y++ Q V+ P C+LL D +++ V L+GL NIL
Sbjct: 380 GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNIL 439
Query: 1525 KVGEAEKVTGNTGDANVFAQLIDDAEGLEKIENLQSHDNTEIYEKAVKILETYWLEED-- 1698
K+ E + A A LI++ GLEKIE LQ+H+N +IY+ A +I++ ++ +D
Sbjct: 440 KMAEDQ--------AETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDID 491
Query: 1699 -DETLPPGDESAQGFQFG 1749
D +L P ES QG FG
Sbjct: 492 EDPSLVP--ESVQGGTFG 507
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,378,909,851
Number of Sequences: 518415
Number of Extensions: 78378909851
Number of Successful Extensions: 523441567
Number of sequences better than 0.0: 0
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