BLASTX 7.6.2
Query= UN18787 /QuerySize=2451
(2450 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|A2XUW1|CDKG2_ORYSI Cyclin-dependent kinase G-2 OS=Oryza sativ... 501 1e-140
sp|Q7XUF4|CDKG2_ORYSJ Cyclin-dependent kinase G-2 OS=Oryza sativ... 501 1e-140
sp|A2X6X1|CDKG1_ORYSI Cyclin-dependent kinase G-1 OS=Oryza sativ... 493 2e-138
sp|Q6K5F8|CDKG1_ORYSJ Cyclin-dependent kinase G-1 OS=Oryza sativ... 477 2e-133
sp|P21127|CD11B_HUMAN Cell division protein kinase 11B OS=Homo s... 398 2e-109
sp|P24788|CDK11_MOUSE Cell division protein kinase 11 OS=Mus mus... 393 6e-108
sp|Q9UQ88|CD11A_HUMAN Cell division protein kinase 11A OS=Homo s... 391 1e-107
sp|P46892|CDK11_RAT Cell division protein kinase 11 OS=Rattus no... 379 5e-104
sp|Q09437|YP62_CAEEL Putative serine/threonine-protein kinase B0... 352 6e-096
sp|Q9VPC0|KP58_DROME Serine/threonine-protein kinase PITSLRE OS=... 348 1e-094
sp|Q55GS4|CDK10_DICDI Probable cyclin-dependent kinase 10 OS=Dic... 334 2e-090
sp|Q3UMM4|CDK10_MOUSE Cell division protein kinase 10 OS=Mus mus... 332 9e-090
sp|Q4KM47|CDK10_RAT Cell division protein kinase 10 OS=Rattus no... 330 5e-089
sp|Q2TBL8|CDK10_BOVIN Cell division protein kinase 10 OS=Bos tau... 329 1e-088
sp|Q15131|CDK10_HUMAN Cell division protein kinase 10 OS=Homo sa... 327 4e-088
sp|Q54RB2|CDK11_DICDI PITSVRE serine/threonine protein-kinase cd... 324 2e-087
sp|O60145|PPK23_SCHPO Serine/threonine-protein kinase ppk23 OS=S... 316 5e-085
sp|P43450|CDK2_CARAU Cell division protein kinase 2 OS=Carassius... 270 3e-071
sp|P23573|CDC2C_DROME Cell division control protein 2 cognate OS... 268 2e-070
sp|P61075|CDC2H_PLAF7 Cell division control protein 2 homolog OS... 247 5e-064
>sp|A2XUW1|CDKG2_ORYSI Cyclin-dependent kinase G-2 OS=Oryza sativa subsp. indica
GN=CDKG-2 PE=2 SV=1
Length = 710
Score = 501 bits (1288), Expect = 1e-140
Identities = 278/552 (50%), Positives = 354/552 (64%), Gaps = 25/552 (4%)
Frame = -3
Query: 1842 KRRKFSPILWD-----DVEDKVSKAPTSREKTRSSFTSLTTNPTRKQD-VDVTLTRKTSP 1681
K+RKFSPI+WD + V+K + + + P QD + L + SP
Sbjct: 135 KKRKFSPIIWDRDSPKPMHSDVAKGKKAVDSVPTELPLPPPPPLPPQDHIPERLAVEKSP 194
Query: 1680 KDQVNVMMSPEPVEAQGPGILNVDVNFARRTSPKDQVNVVMSEEPVDELEEGQLEEEQQV 1501
D + S P + Q V + S ++ D+ EEG +++
Sbjct: 195 MDVEPAVASESPEQLQEHAESRV-MEEEEEYSTMRNISTSRWAGANDDEEEGAPHRKKKS 253
Query: 1500 KQISPVKKLSRWETGLTSHNEEVVSHADNVVPKTSRWNRSSLSPECG-----ELVVSEER 1336
+ +L + + L+ EVV+ + + +RSS S G +L V ++
Sbjct: 254 ASPADSAELGQRKKALSPELGEVVA---SDISGGRTMSRSSDSGRLGADENEDLEVDKDD 310
Query: 1335 QSNSSGSGSGHQSVEKLSANGYSDHEYCSSPNDELEAEEPASPAQGVMNMLLGSRSVNGF 1156
+ G+ + + S++E S E EP P +NML G RSV+ F
Sbjct: 311 YMDVDRDDDGNSDIANHQSGMDSEYEVRRS-----ETPEPVKPPHRCINMLQGCRSVDEF 365
Query: 1155 QKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINILLSCNH 976
++L +INEGTYG+VYRARD+KT EIVALKK+KM++++ GFPLTSLREINILLS +H
Sbjct: 366 ERLNKINEGTYGVVYRARDKKTGEIVALKKVKMEKER----EGFPLTSLREINILLSFHH 421
Query: 975 PSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLLEGVHYL 796
PSIV+VKEVVVG DS ++MVME++EHDLK +ME KQP+S SEVKCLMLQLLEGV YL
Sbjct: 422 PSIVDVKEVVVGSSLDS-IFMVMEYMEHDLKGVMEAMKQPYSQSEVKCLMLQLLEGVKYL 480
Query: 795 HTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGAK 616
H NW++HRDLK SNLL+NN GELKICDFG++RQYGSP+KPYTQ+V+T WYR PELLLG K
Sbjct: 481 HDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQLVVTLWYRAPELLLGTK 540
Query: 615 QYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSSLPNAKA 436
+YSTA+DMWS+GCIMAELL+++PLF GKTE +QL KIF LGTPNE IWPG++ LP K
Sbjct: 541 EYSTAIDMWSVGCIMAELLAKEPLFNGKTEFEQLDKIFRTLGTPNEKIWPGYAKLPGVKV 600
Query: 435 KFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNHSWFHEVP 256
F Q YN LR KFPA SF G ILSE GFDLLN LLT DPEKRL+ + AL H WF EVP
Sbjct: 601 NFVKQPYNRLRDKFPAASFSGRPILSEAGFDLLNNLLTYDPEKRLSADAALQHEWFREVP 660
Query: 255 LPKSQDFMPTFP 220
LPKS+DFMPTFP
Sbjct: 661 LPKSKDFMPTFP 672
>sp|Q7XUF4|CDKG2_ORYSJ Cyclin-dependent kinase G-2 OS=Oryza sativa subsp.
japonica GN=CDKG-2 PE=2 SV=2
Length = 710
Score = 501 bits (1288), Expect = 1e-140
Identities = 278/552 (50%), Positives = 354/552 (64%), Gaps = 25/552 (4%)
Frame = -3
Query: 1842 KRRKFSPILWD-----DVEDKVSKAPTSREKTRSSFTSLTTNPTRKQD-VDVTLTRKTSP 1681
K+RKFSPI+WD + V+K + + + P QD + L + SP
Sbjct: 135 KKRKFSPIIWDRDSPKPMHSDVAKGKKAVDSVPTELPLPPPPPLPPQDHIPERLAVEKSP 194
Query: 1680 KDQVNVMMSPEPVEAQGPGILNVDVNFARRTSPKDQVNVVMSEEPVDELEEGQLEEEQQV 1501
D + S P + Q V + S ++ D+ EEG +++
Sbjct: 195 MDVEPAVASESPEQLQEHAESRV-MEEEEEYSTMRNISTSRWAGANDDEEEGAPHRKKKS 253
Query: 1500 KQISPVKKLSRWETGLTSHNEEVVSHADNVVPKTSRWNRSSLSPECG-----ELVVSEER 1336
+ +L + + L+ EVV+ + + +RSS S G +L V ++
Sbjct: 254 ASPADSAELGQRKKALSPELGEVVA---SDISGGRTMSRSSDSGRLGADENEDLEVDKDD 310
Query: 1335 QSNSSGSGSGHQSVEKLSANGYSDHEYCSSPNDELEAEEPASPAQGVMNMLLGSRSVNGF 1156
+ G+ + + S++E S E EP P +NML G RSV+ F
Sbjct: 311 YMDVDRDDDGNSDIANHQSGMDSEYEVRRS-----ETPEPVKPPHRCINMLQGCRSVDEF 365
Query: 1155 QKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINILLSCNH 976
++L +INEGTYG+VYRARD+KT EIVALKK+KM++++ GFPLTSLREINILLS +H
Sbjct: 366 ERLNKINEGTYGVVYRARDKKTGEIVALKKVKMEKER----EGFPLTSLREINILLSFHH 421
Query: 975 PSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLLEGVHYL 796
PSIV+VKEVVVG DS ++MVME++EHDLK +ME KQP+S SEVKCLMLQLLEGV YL
Sbjct: 422 PSIVDVKEVVVGSSLDS-IFMVMEYMEHDLKGVMEAMKQPYSQSEVKCLMLQLLEGVKYL 480
Query: 795 HTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGAK 616
H NW++HRDLK SNLL+NN GELKICDFG++RQYGSP+KPYTQ+V+T WYR PELLLG K
Sbjct: 481 HDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQLVVTLWYRAPELLLGTK 540
Query: 615 QYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSSLPNAKA 436
+YSTA+DMWS+GCIMAELL+++PLF GKTE +QL KIF LGTPNE IWPG++ LP K
Sbjct: 541 EYSTAIDMWSVGCIMAELLAKEPLFNGKTEFEQLDKIFRTLGTPNEKIWPGYAKLPGVKV 600
Query: 435 KFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNHSWFHEVP 256
F Q YN LR KFPA SF G ILSE GFDLLN LLT DPEKRL+ + AL H WF EVP
Sbjct: 601 NFVKQPYNRLRDKFPAASFSGRPILSEAGFDLLNNLLTYDPEKRLSADAALQHEWFREVP 660
Query: 255 LPKSQDFMPTFP 220
LPKS+DFMPTFP
Sbjct: 661 LPKSKDFMPTFP 672
>sp|A2X6X1|CDKG1_ORYSI Cyclin-dependent kinase G-1 OS=Oryza sativa subsp. indica
GN=CDKG-1 PE=2 SV=1
Length = 693
Score = 493 bits (1269), Expect = 2e-138
Identities = 284/581 (48%), Positives = 363/581 (62%), Gaps = 67/581 (11%)
Frame = -3
Query: 1878 RKGREEGQRPAEKRRKFSPILWDDVEDKVSKAPTSREKTRSSFTSLTTNPTRK-QDVDVT 1702
R +EE + K+RK SP++WD R+ +P R ++VD
Sbjct: 115 RVSKEEAKMSPSKKRKQSPVIWD----------------RNGSQRQARDPVRGIREVDAV 158
Query: 1701 LTRKTSPKD-QVNVMMSPEPV-EAQGPGILNVDVNFARRTSPKDQVNVVMSEEPVDELEE 1528
+ + + VM S + + P IL+V V D+V VDE EE
Sbjct: 159 VAEIIMHQSHSLPVMSSLSSIGDGHSPMILDVSV---------DKVQEYEKNRIVDEEEE 209
Query: 1527 GQL--------------EEEQQV------KQISPVKKLSRWETGLTSHNEEVVSHADNVV 1408
G +EE+ V K +SPV + R T + E N V
Sbjct: 210 GYPTMRNILTSRWADAGDEEENVFVPKKKKSVSPVDSIERGSTKKVTSPESGEVLVYNSV 269
Query: 1407 PKTSRWNRSSLSPECGELVVSEERQSNSSGSGSGHQSVEKLSANGYSDHEYCSS--PNDE 1234
+SR + S + + E+ N VEK + + Y S ++
Sbjct: 270 RSSSRSSDSGVLQGSANRDLEVEKGDNI--------DVEKAADDDYPAGHLLDSDFEGED 321
Query: 1233 LEAEEP---ASPAQGVMNMLLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKI 1063
+E P SP + +NML G RSV+ F++L INEGTYG+V+R RD++T EIVALKK+
Sbjct: 322 CRSETPECTRSPRR-CINMLQGCRSVDEFERLNTINEGTYGVVFRVRDKRTGEIVALKKV 380
Query: 1062 KMKEDKYEEGYGFPLTSLREINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLK 883
KM++++ GFPLTSLRE+NILLS +HPSIV VKEVVV G ND D++MVME++EHDLK
Sbjct: 381 KMEKER----EGFPLTSLREMNILLSFHHPSIVEVKEVVV-GSNDRDIFMVMEYMEHDLK 435
Query: 882 CLMERKKQPFSTSEVKCLMLQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMA 703
+ME KQP+S SEVKCLMLQLLEGV YLH NW++HRDLK SNLL+NN GELKICDFG++
Sbjct: 436 GVMETMKQPYSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLS 495
Query: 702 RQYGSPIKPYTQMVITQWYRPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTEL 523
RQYGSP+KPYTQ+V+T WYR PELLLGAK YSTA+DMWS+GCIM ELLS+ PLF GK+E+
Sbjct: 496 RQYGSPLKPYTQLVVTLWYRAPELLLGAKDYSTAIDMWSLGCIMGELLSKGPLFNGKSEI 555
Query: 522 DQLQKIFAVLGTPNESIWPGFSSLPNAKAKFPTQSYNLLRKKFPAISFVGGQILSERGFD 343
DQL KIF LGTP+E+IWPG+S LP A KF Q++N LR KF A+SF GG +LSE GFD
Sbjct: 556 DQLDKIFRTLGTPDENIWPGYSKLPGATVKFGKQTHNRLRDKFRAVSFTGGPMLSEAGFD 615
Query: 342 LLNGLLTLDPEKRLTVEEALNHSWFHEVPLPKSQDFMPTFP 220
LLN LLT DPEKR++ E+ALNH WF E+PLP+S+DFMPTFP
Sbjct: 616 LLNRLLTYDPEKRISAEDALNHEWFRELPLPRSKDFMPTFP 656
>sp|Q6K5F8|CDKG1_ORYSJ Cyclin-dependent kinase G-1 OS=Oryza sativa subsp.
japonica GN=CDKG-1 PE=2 SV=1
Length = 693
Score = 477 bits (1226), Expect = 2e-133
Identities = 229/337 (67%), Positives = 277/337 (82%), Gaps = 5/337 (1%)
Frame = -3
Query: 1230 EAEEPASPAQGVMNMLLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKE 1051
E E + +NML G RSV+ F++L INEGTYG+V+R RD++T EIVALKK+KM++
Sbjct: 325 ETPECTRSPRRCINMLQGCRSVDEFERLNTINEGTYGVVFRVRDKRTGEIVALKKVKMEK 384
Query: 1050 DKYEEGYGFPLTSLREINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLME 871
++ GFPLTSLRE+NILLS +HPSIV VKEVVV G ND D++MVME++EHDLK +ME
Sbjct: 385 ER----EGFPLTSLREMNILLSFHHPSIVEVKEVVV-GSNDRDIFMVMEYMEHDLKGVME 439
Query: 870 RKKQPFSTSEVKCLMLQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYG 691
KQP+S SEVKCLMLQLLEGV YLH NW++HRDLK SNLL+NN GELKICDFG++RQYG
Sbjct: 440 TMKQPYSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYG 499
Query: 690 SPIKPYTQMVITQWYRPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQ 511
SP+KPYTQ+V+T WYR PELLLGAK YSTA+DMWS+GCIM ELLS+ PLF GK+E+DQL
Sbjct: 500 SPLKPYTQLVVTLWYRAPELLLGAKDYSTAIDMWSLGCIMGELLSKGPLFNGKSEIDQLD 559
Query: 510 KIFAVLGTPNESIWPGFSSLPNAKAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNG 331
KIF LGTP+E+IWPG+S LP A KF Q++N LR KF A+SF GG +LSE GFDLLN
Sbjct: 560 KIFRTLGTPDENIWPGYSKLPGATVKFGKQTHNRLRDKFRAVSFTGGPMLSEAGFDLLNR 619
Query: 330 LLTLDPEKRLTVEEALNHSWFHEVPLPKSQDFMPTFP 220
LLT DPEKR++ E+ALNH WF E+PLP+S+DFMPTFP
Sbjct: 620 LLTYDPEKRISAEDALNHEWFRELPLPRSKDFMPTFP 656
>sp|P21127|CD11B_HUMAN Cell division protein kinase 11B OS=Homo sapiens
GN=CDK11B PE=1 SV=3
Length = 795
Score = 398 bits (1020), Expect = 2e-109
Identities = 222/456 (48%), Positives = 286/456 (62%), Gaps = 31/456 (6%)
Frame = -3
Query: 1554 EEPVDELEEGQLEEEQQVKQISPVKKLSRWETGLTSHNEEVVSHADNVVPKTSRWNRSSL 1375
EE +E EEG EE + ++ ++ ETG S++EE + V +
Sbjct: 308 EEEEEEEEEGSTSEESEEEE--EEEEEEEEETG--SNSEEASEQSAEEVSEEEMSEDEER 363
Query: 1374 SPECGELVVSEERQSNSSGS--------GSGHQSVEKLSANGYSDHEYCSSPNDELEAEE 1219
E LVV E R SG G G L+ Y SP EL+ E
Sbjct: 364 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSP-IELKQEL 422
Query: 1218 PASPAQGVMNMLLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYE 1039
P + L G RSV FQ L +I EGTYG+VYRA+D+KT EIVALK++KM+++K
Sbjct: 423 PK-----YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEK-- 475
Query: 1038 EGYGFPLTSLREINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQ 859
GFP+TSLREIN +L HP+IV V+E+VVG D +Y+VM ++EHDLK LME KQ
Sbjct: 476 --EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHDLKSLMETMKQ 532
Query: 858 PFSTSEVKCLMLQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIK 679
PF EVK LM+QLL GV +LH NWI+HRDLK SNLL+++ G LK+ DFG+AR+YGSP+K
Sbjct: 533 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK 592
Query: 678 PYTQMVITQWYRPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFA 499
YT +V+T WYR PELLLGAK+YSTAVDMWS+GCI ELL+QKPLFPGK+E+DQ+ K+F
Sbjct: 593 AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFK 652
Query: 498 VLGTPNESIWPGFSSLPNA-KAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLT 322
LGTP+E IWPG+S LP K F YN LRK+F G +LS++GFDL+N LT
Sbjct: 653 DLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRF-------GALLSDQGFDLMNKFLT 705
Query: 321 LDPEKRLTVEEALNHSWFHEVPLPKSQDFMPTFPPR 214
P +R++ E+ L H +F E PLP PT+P +
Sbjct: 706 YFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAK 741
>sp|P24788|CDK11_MOUSE Cell division protein kinase 11 OS=Mus musculus GN=Cdk11
PE=1 SV=2
Length = 784
Score = 393 bits (1007), Expect = 6e-108
Identities = 220/455 (48%), Positives = 287/455 (63%), Gaps = 28/455 (6%)
Frame = -3
Query: 1554 EEPVDELEEGQLEEEQQVKQISPVKKLSRWETGLTSHNEEVVSHADNVVPKTSRWNRSSL 1375
EE +E EEG EE + ++ ++ ETG S++EE + V
Sbjct: 296 EEEEEEEEEGSTSEESEEEE-EEEEEEEEEETG--SNSEEASEQSAEEVSDEEMSEDEDR 352
Query: 1374 SPECGELVVSEERQSNSSG-SGSGHQSVEKLSANGYSDHEYCSSPND------ELEAEEP 1216
E LVV E R SG S G + V + + + E P+ EL+ E P
Sbjct: 353 ENENHILVVPESRFDRDSGDSEEGEEEVGEGTPQSSAPTEGDYVPDSPALSPIELKQELP 412
Query: 1215 ASPAQGVMNMLLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEE 1036
+ L G RSV FQ L +I EGTYG+VYRA+D+KT EIVALK++KM+++K
Sbjct: 413 K-----YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEK--- 464
Query: 1035 GYGFPLTSLREINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQP 856
GFP+TSLREIN +L HP+IV V+E+VVG D +Y+VM ++EHDLK LME KQP
Sbjct: 465 -EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHDLKSLMETMKQP 522
Query: 855 FSTSEVKCLMLQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKP 676
F EVK LM+QLL GV +LH NWI+HRDLK SNLL+++ G LK+ DFG+AR+YGSP+K
Sbjct: 523 FLPGEVKTLMIQLLSGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 582
Query: 675 YTQMVITQWYRPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAV 496
YT +V+T WYR PELLLGAK+YSTAVDMWS+GCI ELL+QKPLFPGK+++DQ+ KIF
Sbjct: 583 YTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKD 642
Query: 495 LGTPNESIWPGFSSLPNA-KAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTL 319
LGTP+E IWPG++ LP K F YN LRK+F G +LS++GFDL+N LT
Sbjct: 643 LGTPSEKIWPGYNDLPAVKKMTFSEYPYNNLRKRF-------GALLSDQGFDLMNKFLTY 695
Query: 318 DPEKRLTVEEALNHSWFHEVPLPKSQDFMPTFPPR 214
P +R+ E+ L H +F E PLP PT+P +
Sbjct: 696 YPGRRINAEDGLKHEYFRETPLPIDPSMFPTWPAK 730
>sp|Q9UQ88|CD11A_HUMAN Cell division protein kinase 11A OS=Homo sapiens
GN=CDK11A PE=1 SV=3
Length = 780
Score = 391 bits (1004), Expect = 1e-107
Identities = 216/469 (46%), Positives = 285/469 (60%), Gaps = 25/469 (5%)
Frame = -3
Query: 1596 RRTSPKDQVNVVMSEEPVDELEEGQLEEEQQVKQISPVKKLSRWETGLTSHNEEVVSHAD 1417
R+TS + + +E EE + EEE+ ++ E S++EE +
Sbjct: 275 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEETGSNSEEASEQSA 334
Query: 1416 NVVPKTSRWNRSSLSPECGELVVSEERQSNSSGSGSGHQSVEKLSANGYSDHEYCSSPND 1237
V + E LVV E R SG +S E G + +
Sbjct: 335 EEVSEEEMSEDEERENENHLLVVPESRFDRDSG-----ESEEAEEEVGEGTPQSSALTEG 389
Query: 1236 ELEAEEPA-------SPAQGVMNMLLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIV 1078
+ + PA + L G RSV FQ L +I EGTYG+VYRA+D+KT EIV
Sbjct: 390 DYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIV 449
Query: 1077 ALKKIKMKEDKYEEGYGFPLTSLREINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHL 898
ALK++KM+++K GFP+TSLREIN +L HP+IV V+E+VVG D +Y+VM ++
Sbjct: 450 ALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYV 504
Query: 897 EHDLKCLMERKKQPFSTSEVKCLMLQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKIC 718
EHDLK LME KQPF EVK LM+QLL GV +LH NWI+HRDLK SNLL+++ G LK+
Sbjct: 505 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVG 564
Query: 717 DFGMARQYGSPIKPYTQMVITQWYRPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFP 538
DFG+AR+YGSP+K YT +V+TQWYR PELLLGAK+YSTAVDMWS+GCI ELL+QKPLFP
Sbjct: 565 DFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 624
Query: 537 GKTELDQLQKIFAVLGTPNESIWPGFSSLPNA-KAKFPTQSYNLLRKKFPAISFVGGQIL 361
G +E+DQ+ K+F LGTP+E IWPG+S LP K F YN LRK+F G +L
Sbjct: 625 GNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRF-------GALL 677
Query: 360 SERGFDLLNGLLTLDPEKRLTVEEALNHSWFHEVPLPKSQDFMPTFPPR 214
S++GFDL+N LT P +R++ E+ L H +F E PLP PT+P +
Sbjct: 678 SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAK 726
>sp|P46892|CDK11_RAT Cell division protein kinase 11 OS=Rattus norvegicus
GN=Cdk11 PE=2 SV=1
Length = 436
Score = 379 bits (973), Expect = 5e-104
Identities = 187/325 (57%), Positives = 237/325 (72%), Gaps = 13/325 (4%)
Frame = -3
Query: 1185 LLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLR 1006
L G RSV FQ L +I EGTYG+VYRA+D+KT EIVALK++KM+++K GFPLTS+R
Sbjct: 70 LQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEK----EGFPLTSIR 125
Query: 1005 EINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLM 826
EIN +L HP+IV V+E+VVG D +Y+VM ++EHDLK LME KQPF EVK LM
Sbjct: 126 EINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLM 184
Query: 825 LQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWY 646
+QLL GV +LH NWI+HRDLK SNLL+ + G LK+ DFG+AR+YGSP+K YT +V+T WY
Sbjct: 185 IQLLSGVKHLHDNWILHRDLKTSNLLLTHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 244
Query: 645 RPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWP 466
R PELLLGAK+YSTA DMWS+GCI ELL+QKPLFPGK+++DQ+ KIF +GTP+E IWP
Sbjct: 245 RAPELLLGAKEYSTACDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKDIGTPSEKIWP 304
Query: 465 GFSSLPNA-KAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEE 289
G+S LP K F YN LRK+F G +LS++GFDL+N LT P +R+ E+
Sbjct: 305 GYSELPAVKKMTFSELPYNNLRKRF-------GALLSDQGFDLMNKFLTYYPGRRINAED 357
Query: 288 ALNHSWFHEVPLPKSQDFMPTFPPR 214
L H +F E PLP PT+P +
Sbjct: 358 GLKHEYFRETPLPIDPSMFPTWPAK 382
>sp|Q09437|YP62_CAEEL Putative serine/threonine-protein kinase B0495.2
OS=Caenorhabditis elegans GN=B0495.2 PE=2 SV=1
Length = 719
Score = 352 bits (903), Expect = 6e-096
Identities = 173/329 (52%), Positives = 239/329 (72%), Gaps = 15/329 (4%)
Frame = -3
Query: 1185 LLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLR 1006
L+G R+++ ++ + +++EGT+G+VYR +D++T EIVALK++KM+++K GFP+T+LR
Sbjct: 347 LMGCRNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEK----EGFPITALR 402
Query: 1005 EINILLSC-NHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCL---MERKKQPFSTSEV 838
EIN+LL NHP+IVNVKE+++G D +YM ME +EHD+K L M R+ + FS E
Sbjct: 403 EINMLLKAGNHPNIVNVKEILLGSNMDK-IYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQ 461
Query: 837 KCLMLQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVI 658
K L+ QLL G+ ++H WI+HRDLK SNLLM++ G LKI DFG+AR+YG P+K +T +V+
Sbjct: 462 KTLLQQLLSGIEHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVV 521
Query: 657 TQWYRPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNE 478
T WYR PELLLG + YST VDMWS+GCIMAE + KPLFPG+ EL+Q++KIF +GTP E
Sbjct: 522 TLWYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTE 581
Query: 477 SIWPGFSSLPNAKA-KFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRL 301
SIWPG + L KA F YN LRK+ F+ G++L++ GF LLNGLLTLDP+ R
Sbjct: 582 SIWPGVTELDGWKALTFEKYPYNQLRKR-----FLAGRLLNDTGFKLLNGLLTLDPKNRF 636
Query: 300 TVEEALNHSWFHEVPLPKSQDFMPTFPPR 214
+ +AL+H WF E P P + PTFP +
Sbjct: 637 SATQALDHEWFTEEPYPVPPEEFPTFPAK 665
>sp|Q9VPC0|KP58_DROME Serine/threonine-protein kinase PITSLRE OS=Drosophila
melanogaster GN=Pitslre PE=1 SV=1
Length = 952
Score = 348 bits (892), Expect = 1e-094
Identities = 179/354 (50%), Positives = 238/354 (67%), Gaps = 21/354 (5%)
Frame = -3
Query: 1248 SPNDELEAEEPASPAQGVMNMLLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALK 1069
S +++ ++ P + G RSV FQ L +I EGTYG+VYRA+D++T EIVALK
Sbjct: 528 SLEEQIPCDDKGIPLPNYYPGVQGCRSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALK 587
Query: 1068 KIKMKEDKYEEGYGFPLTSLREINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHD 889
++KM+++K GFP+TSLREIN LL HP+IV V+E+VVG D +++VM+++EHD
Sbjct: 588 RLKMEKEK----EGFPITSLREINTLLKGQHPNIVTVREIVVGSNMDK-IFIVMDYVEHD 642
Query: 888 LKCLME---RKKQPFSTSEVKCLMLQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKIC 718
LK LME +KQ F EVKCL QLL V +LH NWI+HRDLK SNLL+++ G LK+
Sbjct: 643 LKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVG 702
Query: 717 DFGMARQYGSPIKPYTQMVITQWYRPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFP 538
DFG+AR+YGSPIK YT +V+T WYR PELLL + YST +D+WS+GCI AE L PLFP
Sbjct: 703 DFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLFP 762
Query: 537 GKTELDQLQKIFAVLGTPNESIWPGFSSLPNAK------AKFPTQSYNLLRKKFPAISFV 376
GK+E+D+L +IF LGTPNE IWPG++ LP K ++F + LRK F
Sbjct: 763 GKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQ----- 817
Query: 375 GGQILSERGFDLLNGLLTLDPEKRLTVEEALNHSWFHEVPLPKSQDFMPTFPPR 214
+ SE G LL GLLT DP++RL+ + AL H +F E+PLP PT+P +
Sbjct: 818 --EKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPLPIDPSMFPTWPAK 869
>sp|Q55GS4|CDK10_DICDI Probable cyclin-dependent kinase 10 OS=Dictyostelium
discoideum GN=cdk10 PE=2 SV=1
Length = 366
Score = 334 bits (856), Expect = 2e-090
Identities = 169/315 (53%), Positives = 217/315 (68%), Gaps = 14/315 (4%)
Frame = -3
Query: 1158 FQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINILLSCN 979
F+KL I EGTYGIV + RD++T IVALKK+K+ + ++ G PLTSLREI IL
Sbjct: 7 FEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQ---QDKDGIPLTSLREIQILKEIK 63
Query: 978 HPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLLEGVHY 799
HP+IV++ EVV+G D +Y+V E+LEHD+ L++ +PF SE+KC +LQLL V Y
Sbjct: 64 HPNIVSLLEVVIGSTGDK-IYLVFEYLEHDVASLIDNINKPFKLSEIKCFLLQLLRAVEY 122
Query: 798 LHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGA 619
LH++WIIHRDLK SNLL N G LK+ DFG+AR++G PI+ T ++T WYR PELLLG
Sbjct: 123 LHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGC 182
Query: 618 KQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSSLPNAK 439
++YSTAVD+WSIG I ELL +PL G E+DQ+ +IF +LG PNE IWPGFSSLPN K
Sbjct: 183 QKYSTAVDLWSIGSIFGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFK 242
Query: 438 A--KFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNHSWFH 265
P Q YN LR+ P I S+ FDLLN LLT DP KR+T +A+ H +F+
Sbjct: 243 RLNNIPHQPYNNLRELVPTI--------SDTAFDLLNQLLTYDPTKRITASDAIKHPFFY 294
Query: 264 EVPLPKSQDFMPTFP 220
E P P+S + MP FP
Sbjct: 295 ENPFPQSIEMMPKFP 309
>sp|Q3UMM4|CDK10_MOUSE Cell division protein kinase 10 OS=Mus musculus GN=Cdk10
PE=2 SV=1
Length = 360
Score = 332 bits (850), Expect = 9e-090
Identities = 173/322 (53%), Positives = 221/322 (68%), Gaps = 14/322 (4%)
Frame = -3
Query: 1173 RSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINI 994
RSV F+KL +I EGTYGIVYRARD +T EIVALKK++M ++K G P++SLREI +
Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEK----DGIPISSLREITL 89
Query: 993 LLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLL 814
LL HP+IV +KEVVVG +S +++VM + E DL L+E PFS ++VKC+MLQ+L
Sbjct: 90 LLRLRHPNIVELKEVVVGNHLES-IFLVMGYCEQDLASLLENMPTPFSEAQVKCIMLQVL 148
Query: 813 EGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPE 634
G+ YLH N+IIHRDLK SNLLM + G +K DFG+AR YG P+KP T V+T WYR PE
Sbjct: 149 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 208
Query: 633 LLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSS 454
LLLG +T++DMW++GCI+AELL+ KPL PG +E+ Q+ I +LGTP+E+IWPGFS
Sbjct: 209 LLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSK 268
Query: 453 LPNA-KAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNH 277
LP A + Q YN L+ KFP LSE G LLN L DP+KR T + L
Sbjct: 269 LPLAGQYSLRKQPYNNLKHKFP--------WLSEAGLRLLNFLFMYDPKKRATSGDCLES 320
Query: 276 SWFHEVPLPKSQDFMPTFPPRR 211
S+F E PLP + MPTFP R
Sbjct: 321 SYFKEKPLPCEPELMPTFPHHR 342
>sp|Q4KM47|CDK10_RAT Cell division protein kinase 10 OS=Rattus norvegicus
GN=Cdk10 PE=2 SV=1
Length = 358
Score = 330 bits (844), Expect = 5e-089
Identities = 171/322 (53%), Positives = 221/322 (68%), Gaps = 14/322 (4%)
Frame = -3
Query: 1173 RSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINI 994
RSV F+KL +I EGTYGIVYRARD +T EIVALKK++M ++K G P++SLREI +
Sbjct: 32 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEK----DGIPISSLREITL 87
Query: 993 LLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLL 814
LL HP+IV +KEVVVG +S +++VM + E DL L+E PFS ++VKC++LQ+L
Sbjct: 88 LLRLRHPNIVELKEVVVGNHLES-IFLVMGYCEQDLASLLENMPTPFSEAQVKCILLQVL 146
Query: 813 EGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPE 634
G+ YLH ++IIHRDLK SNLLM + G +K DFG+AR YG P+KP T V+T WYR PE
Sbjct: 147 RGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 206
Query: 633 LLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSS 454
LLLG +T++DMW++GCI+AELL+ KPL PG +E+ Q+ I +LGTP+E+IWPGFS
Sbjct: 207 LLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSK 266
Query: 453 LPNA-KAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNH 277
LP A + Q YN L+ KFP LSE G LLN L DP+KR T + L
Sbjct: 267 LPLAGQYSLRKQPYNNLKHKFP--------WLSEAGLRLLNFLFMYDPKKRATAGDCLES 318
Query: 276 SWFHEVPLPKSQDFMPTFPPRR 211
S+F E PLP + MPTFP R
Sbjct: 319 SYFKEKPLPCEPELMPTFPHHR 340
>sp|Q2TBL8|CDK10_BOVIN Cell division protein kinase 10 OS=Bos taurus GN=CDK10
PE=2 SV=1
Length = 361
Score = 329 bits (841), Expect = 1e-088
Identities = 171/322 (53%), Positives = 220/322 (68%), Gaps = 14/322 (4%)
Frame = -3
Query: 1173 RSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINI 994
RSV F+KL +I EGTYGIVYRARD T EIVALKK++M ++K G P++SLREI +
Sbjct: 32 RSVKEFEKLNRIGEGTYGIVYRARDTHTDEIVALKKVRMDKEK----DGVPISSLREITL 87
Query: 993 LLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLL 814
LL HP+IV +KEVVVG +S +++VM + E DL L+E PFS ++VKC++LQ+L
Sbjct: 88 LLRLRHPNIVELKEVVVGNHLES-IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVL 146
Query: 813 EGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPE 634
G+ YLH N+IIHRDLK SNLLM + G +K DFG+AR YG P+KP T V+T WYR PE
Sbjct: 147 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGIPVKPMTPKVVTLWYRAPE 206
Query: 633 LLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSS 454
LLLG +T++DMW++GCI+AELL+ KPL PG +E+ Q+ I +LGTP+E+IWPGFS
Sbjct: 207 LLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQVDLIVQLLGTPSENIWPGFSQ 266
Query: 453 LPNA-KAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNH 277
LP A + Q YN L+ KFP LSE G L+N L DP+KR T + L
Sbjct: 267 LPLASQYSLRKQPYNNLKHKFP--------WLSEAGLRLMNLLFMYDPKKRATAGDCLES 318
Query: 276 SWFHEVPLPKSQDFMPTFPPRR 211
S+F E PLP + MPTFP R
Sbjct: 319 SYFKEKPLPCEPELMPTFPHHR 340
>sp|Q15131|CDK10_HUMAN Cell division protein kinase 10 OS=Homo sapiens GN=CDK10
PE=1 SV=1
Length = 360
Score = 327 bits (836), Expect = 4e-088
Identities = 169/322 (52%), Positives = 220/322 (68%), Gaps = 14/322 (4%)
Frame = -3
Query: 1173 RSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINI 994
RSV F+KL +I EGTYGIVYRARD +T EIVALKK++M ++K G P++SLREI +
Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEK----DGIPISSLREITL 89
Query: 993 LLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLL 814
LL HP+IV +KEVVVG +S +++VM + E DL L+E PFS ++VKC++LQ+L
Sbjct: 90 LLRLRHPNIVELKEVVVGNHLES-IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVL 148
Query: 813 EGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPE 634
G+ YLH N+IIHRDLK SNLLM + G +K DFG+AR YG P+KP T V+T WYR PE
Sbjct: 149 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPE 208
Query: 633 LLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSS 454
LLLG +T++DMW++GCI+AELL+ +PL PG +E+ Q+ I +LGTP+E+IWPGFS
Sbjct: 209 LLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSK 268
Query: 453 LP-NAKAKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNH 277
LP + Q YN L+ KFP LSE G LL+ L DP+KR T + L
Sbjct: 269 LPLVGQYSLRKQPYNNLKHKFP--------WLSEAGLRLLHFLFMYDPKKRATAGDCLES 320
Query: 276 SWFHEVPLPKSQDFMPTFPPRR 211
S+F E PLP + MPTFP R
Sbjct: 321 SYFKEKPLPCEPELMPTFPHHR 342
>sp|Q54RB2|CDK11_DICDI PITSVRE serine/threonine protein-kinase cdk11
OS=Dictyostelium discoideum GN=cdk11 PE=3 SV=1
Length = 358
Score = 324 bits (829), Expect = 2e-087
Identities = 162/318 (50%), Positives = 222/318 (69%), Gaps = 14/318 (4%)
Frame = -3
Query: 1173 RSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINI 994
RSV+ F+KL INEG +G+VY A+D++T+EIVALKKIKM+ ++ G P+TS+REI +
Sbjct: 47 RSVDCFKKLYTINEGAFGVVYCAQDKETEEIVALKKIKMERER----EGIPITSVREIKV 102
Query: 993 LLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLL 814
L+ H +IV +KE+V+ GKN + ++M ME ++HDL+ LME K+PF SE+K L+ QLL
Sbjct: 103 LMELKHDNIVQIKEIVL-GKNINSIFMAMEFIDHDLRGLMEVIKKPFLPSEIKTLIQQLL 161
Query: 813 EGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPE 634
GV Y+H NW+IHRDLK +NLL N G LKI DFG+AR+YGSP+KP ++ V+T WYR PE
Sbjct: 162 NGVSYMHDNWVIHRDLKTANLLYTNKGVLKIADFGLAREYGSPLKPLSKGVVTLWYRAPE 221
Query: 633 LLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSS 454
LLL + Y+ A+D+WS+GCI AE++S++ L G +E+DQ+ KIF + GTP E WP F
Sbjct: 222 LLLDTEIYTPAIDIWSVGCIFAEIISKEVLLQGSSEIDQMDKIFKLFGTPTEKSWPAFFK 281
Query: 453 LPNAK-AKFPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNH 277
LP AK Q YN L+ KFP I ++ FDLLN LL L+PE R++ +AL H
Sbjct: 282 LPLAKYFNLTDQPYNNLKSKFPHI--------TDNAFDLLNKLLELNPEARISASDALKH 333
Query: 276 SWFHEVPLPKSQDFMPTF 223
+F E P P+ MPT+
Sbjct: 334 PYFFENPQPRDPLLMPTW 351
>sp|O60145|PPK23_SCHPO Serine/threonine-protein kinase ppk23
OS=Schizosaccharomyces pombe GN=ppk23 PE=2 SV=1
Length = 398
Score = 316 bits (809), Expect = 5e-085
Identities = 165/326 (50%), Positives = 218/326 (66%), Gaps = 15/326 (4%)
Frame = -3
Query: 1185 LLGSRSVNGFQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLR 1006
L S++ ++ L++I EG+YGIVYR D+ T +VALKKIK + G GFP+TSLR
Sbjct: 65 LKSCNSIDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPN----GIGFPITSLR 120
Query: 1005 EINILLSCNHPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLM 826
EI L S H +IV +++VVV GK+ DVY+VME +EHDLK L++ + F SEVK LM
Sbjct: 121 EIESLSSIRHDNIVELEKVVV-GKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLM 179
Query: 825 LQLLEGVHYLHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWY 646
LQLL ++H +W +HRDLKPSNLLMNNTGE+K+ DFG+AR P T++V+T WY
Sbjct: 180 LQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWY 239
Query: 645 RPPELLLGAKQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWP 466
R PELLLGA Y +DMWSIGCI AE++++ PLF GK+ELDQL KIF +LG P WP
Sbjct: 240 RAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWP 299
Query: 465 GFSSLPNA-KAKFPT-QSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVE 292
+ LP A K K PT +++ +R P L+ +DLLN LL+L+P KR++ +
Sbjct: 300 QYFLLPYANKIKHPTVPTHSKIRTSIPN--------LTGNAYDLLNRLLSLNPAKRISAK 351
Query: 291 EALNHSWFHEVPLPKSQDFMPTFPPR 214
EAL H +F+E P PK F PTFP +
Sbjct: 352 EALEHPYFYESPRPKDPKFFPTFPSK 377
>sp|P43450|CDK2_CARAU Cell division protein kinase 2 OS=Carassius auratus
GN=cdk2 PE=2 SV=1
Length = 298
Score = 270 bits (690), Expect = 3e-071
Identities = 138/298 (46%), Positives = 198/298 (66%), Gaps = 16/298 (5%)
Frame = -3
Query: 1149 LKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINILLSCNHPS 970
+++I EGTYG+VY+A+++ T E VALKKI++ E G P T++REI++L NHP+
Sbjct: 7 VEKIGEGTYGVVYKAKNKVTGETVALKKIRLD----TETEGVPSTAIREISLLKELNHPN 62
Query: 969 IVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKK-QPFSTSEVKCLMLQLLEGVHYLH 793
IV + +V+ ++ +Y+V E L DLK M+ S VK + QLL+G+ + H
Sbjct: 63 IVKLHDVI---HTENKLYLVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQGLAFCH 119
Query: 792 TNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGAKQ 613
++ ++HRDLKP NLL+N GE+K+ DFG+AR +G P++ YT V+T WYR PE+LLG K
Sbjct: 120 SHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKY 179
Query: 612 YSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSSLPNAKAK 433
YSTAVD+WS+GCI AE++++K LFPG +E+DQL +IF LGTP+ESIWPG +S+P+ K
Sbjct: 180 YSTAVDIWSLGCIFAEMITRKALFPGDSEIDQLFRIFRTLGTPDESIWPGVTSMPDYKPS 239
Query: 432 FPTQSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNHSWFHEV 259
FP + L K P L E G DLL +L DP KR++ + AL H +F +V
Sbjct: 240 FPKWARQDLSKVVPP--------LDEDGRDLLGQMLIYDPNKRISAKNALVHRFFRDV 289
>sp|P23573|CDC2C_DROME Cell division control protein 2 cognate OS=Drosophila
melanogaster GN=cdc2c PE=1 SV=1
Length = 314
Score = 268 bits (683), Expect = 2e-070
Identities = 132/301 (43%), Positives = 198/301 (65%), Gaps = 19/301 (6%)
Frame = -3
Query: 1158 FQKLKQINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINILLSCN 979
FQ+ ++I EGTYGIVY+AR T + VALKKI+++ E G P T++REI++L +
Sbjct: 8 FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLE----GETEGVPSTAIREISLLKNLK 63
Query: 978 HPSIVNVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLLEGVHY 799
HP++V + +VV+ G N +YM+ E+L DLK LM++KK F+ +K M Q+L+ V +
Sbjct: 64 HPNVVQLFDVVISGNN---LYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGF 120
Query: 798 LHTNWIIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGA 619
HTN I+HRDLKP NLL++ G++K+ DFG+AR + P++ YT V+T WYR PE+LLG
Sbjct: 121 CHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGT 180
Query: 618 KQYSTAVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSSLPNAK 439
K YST VD+WS+GCI +E++ ++ LFPG +E+DQL +IF L TP+E+ WPG + LP+ K
Sbjct: 181 KFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFK 240
Query: 438 AKFPT-QSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEALNHSWFHE 262
KFP + N+ + I +L+ +L DP R++ ++AL H++F
Sbjct: 241 TKFPRWEGTNMPQ-----------PITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRN 289
Query: 261 V 259
V
Sbjct: 290 V 290
>sp|P61075|CDC2H_PLAF7 Cell division control protein 2 homolog OS=Plasmodium
falciparum (isolate 3D7) GN=CRK2 PE=3 SV=1
Length = 288
Score = 247 bits (628), Expect = 5e-064
Identities = 128/287 (44%), Positives = 185/287 (64%), Gaps = 16/287 (5%)
Frame = -3
Query: 1143 QINEGTYGIVYRARDEKTKEIVALKKIKMKEDKYEEGYGFPLTSLREINILLSCNHPSIV 964
+I EGTYG+VY+A++ E ALKKI+++ +E G P T++REI+IL H +IV
Sbjct: 9 KIGEGTYGVVYKAQN-NYGETFALKKIRLE----KEDEGIPSTTIREISILKELKHSNIV 63
Query: 963 NVKEVVVGGKNDSDVYMVMEHLEHDLKCLMERKKQPFSTSEVKCLMLQLLEGVHYLHTNW 784
+ +V+ K + +V EHL+ DLK L++ + + K +LQLL G+ Y H
Sbjct: 64 KLYDVIHTKKR---LVLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNGIAYCHDRR 120
Query: 783 IIHRDLKPSNLLMNNTGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGAKQYST 604
++HRDLKP NLL+N GELKI DFG+AR +G P++ YT V+T WYR P++L+G+K+YST
Sbjct: 121 VLHRDLKPQNLLINREGELKIADFGLARAFGIPVRKYTHEVVTLWYRAPDVLMGSKKYST 180
Query: 603 AVDMWSIGCIMAELLSQKPLFPGKTELDQLQKIFAVLGTPNESIWPGFSSLPNAKAKFPT 424
+D+WS+GCI AE+++ PLFPG +E DQL +IF +LGTPN WP + LP F
Sbjct: 181 TIDIWSVGCIFAEMVNGTPLFPGVSEADQLMRIFRILGTPNSKNWPNVTELPKYDPNF-- 238
Query: 423 QSYNLLRKKFPAISFVGGQILSERGFDLLNGLLTLDPEKRLTVEEAL 283
+ + P SF+ G L E G DLL+ +L LDP +R+T ++AL
Sbjct: 239 ----TVYEPLPWESFLKG--LDESGIDLLSKMLKLDPNQRITAKQAL 279
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,378,909,851
Number of Sequences: 518415
Number of Extensions: 78378909851
Number of Successful Extensions: 523441567
Number of sequences better than 0.0: 0
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