BLASTX 7.6.2

Query= UN18929 /QuerySize=1219
        (1218 letters)

Database: UniProt/SwissProt;
          518,415 sequences; 182,829,261 total letters
                                                                  Score    E
Sequences producing significant alignments:                       (bits) Value

sp|Q9NUN7|ACER3_HUMAN Alkaline ceramidase 3 OS=Homo sapiens GN=A...    125   7e-028
sp|P38298|YPC1_YEAST Alkaline ceramidase YPC1 OS=Saccharomyces c...     76   5e-013
sp|Q02896|YDC1_YEAST Alkaline ceramidase YDC1 OS=Saccharomyces c...     74   1e-012
sp|Q8TDN7|ACER1_HUMAN Alkaline ceramidase 1 OS=Homo sapiens GN=A...     60   2e-008
sp|Q9VIP7|ACASE_DROME Alkaline ceramidase OS=Drosophila melanoga...     55   9e-007
sp|Q8R4X1|ACER1_MOUSE Alkaline ceramidase 1 OS=Mus musculus GN=A...     54   2e-006

>sp|Q9NUN7|ACER3_HUMAN Alkaline ceramidase 3 OS=Homo sapiens GN=ACER3 PE=1 SV=3

          Length = 267

 Score =  125 bits (313), Expect = 7e-028
 Identities = 70/258 (27%), Positives = 128/258 (49%), Gaps = 20/258 (7%)
 Frame = +3

Query: 261 FWGPVTSTIECCEKNYAYSSYIAEFYNTISGLPGILLALIGLVNAIRQRFEKRFSILHIS 440
           +WGP TST++ CE+NY+ + YIAEF+NT+S L  I+  + G V ++R   EKR+   +++
Sbjct:  10 YWGPTTSTLDWCEENYSVTWYIAEFWNTVSNLIMIIPPMFGAVQSVRDGLEKRYIASYLA 69

Query: 441 NMILAIGSMLYHATLQHVQQQSDETPMVWEILLYMYILY-------SPDWHYRSTMPTFL 599
             ++ +GS  +H TL++  Q  DE PM++   +++Y ++       S ++H   T    L
Sbjct:  70 LTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKIKNSVNYHLLFT----L 125

Query: 600 FLYGAAFAAVHAYLRFGIGFKIHYVILCLLCIPRMYKYYIHTEDTAAKRIAKWYVATILV 779
            L+      V+  ++  I  ++ Y +L    + R   Y +       + +    +   L+
Sbjct: 126 VLFSLIVTTVYLKVKEPIFHQVMYGMLVFTLVLRSI-YIVTWVYPWLRGLGYTSLGIFLL 184

Query: 780 GSVCWFCDRVFCKTISQW--------PVNPQGHALWHVFMSFNSYCANTFLMFCRAQQRG 935
           G + W  D +FC+++  +         +  Q HA WH+     SY    F ++ R     
Sbjct: 185 GFLFWNIDNIFCESLRNFRKKVPPIIGITTQFHAWWHILTGLGSYLHILFSLYTRTLYLR 244

Query: 936 WNPKVKYFLGVLPYVKIE 989
           + PKVK+  G+ P +  E
Sbjct: 245 YRPKVKFLFGIWPVILFE 262

>sp|P38298|YPC1_YEAST Alkaline ceramidase YPC1 OS=Saccharomyces cerevisiae
        GN=YPC1 PE=1 SV=1

          Length = 316

 Score =  76 bits (185), Expect = 5e-013
 Identities = 36/92 (39%), Positives = 57/92 (61%)
 Frame = +3

Query: 264 WGPVTSTIECCEKNYAYSSYIAEFYNTISGLPGILLALIGLVNAIRQRFEKRFSILHISN 443
           WG  TSTI+ CE+NY  S YIAE+ NT++    IL A+    +A + + EKRF ++    
Sbjct:  17 WGETTSTIDWCEENYVVSPYIAEWSNTLTNSVFILSAIYTTYSAYKNKLEKRFLLIGFGY 76

Query: 444 MILAIGSMLYHATLQHVQQQSDETPMVWEILL 539
            ++ +GS L+H TL++  Q  DE PM++ + +
Sbjct:  77 GLVGVGSWLFHMTLKYRFQLLDELPMIYAMCI 108

>sp|Q02896|YDC1_YEAST Alkaline ceramidase YDC1 OS=Saccharomyces cerevisiae
        GN=YDC1 PE=1 SV=1

          Length = 317

 Score =  74 bits (181), Expect = 1e-012
 Identities = 35/103 (33%), Positives = 61/103 (59%)
 Frame = +3

Query: 252 MSSFWGPVTSTIECCEKNYAYSSYIAEFYNTISGLPGILLALIGLVNAIRQRFEKRFSIL 431
           +  +WG  TS I+ CE+NY  S YIAE+ NTI+    ++ A     +A R + E R+ ++
Sbjct:  12 IEGYWGKPTSLIDWCEENYVVSPYIAEWSNTITNSIFLMTAFYSTYSAWRNKLETRYILI 71

Query: 432 HISNMILAIGSMLYHATLQHVQQQSDETPMVWEILLYMYILYS 560
            +   ++ IGS L+H TLQ+  Q  DE PM++  ++  + +++
Sbjct:  72 GMGFSLVGIGSWLFHMTLQYRYQLLDELPMLYATIIPSWSIFA 114

>sp|Q8TDN7|ACER1_HUMAN Alkaline ceramidase 1 OS=Homo sapiens GN=ACER1 PE=2 SV=1

          Length = 264

 Score =  60 bits (145), Expect = 2e-008
 Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 7/118 (5%)
 Frame = +3

Query: 252 MSSFWGPVTSTIECCEKNYAYSSYIAEFYNTISGLPGILLA--LIGLVNAIRQRFEKRFS 425
           M S +   +S ++ CE N+ YS  +AEFYNT S +P  +    ++ L++   Q+  +   
Sbjct:   1 MPSIFAYQSSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIY 60

Query: 426 ILHISNMILAIGSMLYHATLQHVQQQSDETPMVWEILLYMYILYSPDWHYRSTMPTFL 599
           ++ +  MI+ + SM +H TL  + Q  DE  ++W +L   Y ++ P    R   P+FL
Sbjct:  61 VVWVLFMIIGLFSMYFHMTLSFLGQLLDEIAILW-LLGSGYSIWMP----RCYFPSFL 113

>sp|Q9VIP7|ACASE_DROME Alkaline ceramidase OS=Drosophila melanogaster GN=bwa
        PE=2 SV=2

          Length = 283

 Score =  55 bits (131), Expect = 9e-007
 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
 Frame = +3

Query: 270 PVTSTIECCEKNYAYSSYIAEFYNTISGLPGILL--ALIGLVNAIRQRFEKRFSILHISN 443
           P +S ++ CE NY  SS IAEF NT S    ILL   LI L     +       ++ +  
Sbjct:  22 PGSSPVDWCEGNYLISSNIAEFVNTFSNFLFILLPPVLIMLFKEYGRFVTPGIHVIWVLL 81

Query: 444 MILAIGSMLYHATLQHVQQQSDETPMVWEILLYMYILYSPDWHY 575
           +++ + SM +HATL  + Q  DE  ++W + +  + L+ P  +Y
Sbjct:  82 IVVGLSSMYFHATLSLIGQLLDELAILW-VFMAAFSLFYPKRYY 124

>sp|Q8R4X1|ACER1_MOUSE Alkaline ceramidase 1 OS=Mus musculus GN=Acer1 PE=1 SV=1

          Length = 273

 Score =  54 bits (129), Expect = 2e-006
 Identities = 31/110 (28%), Positives = 61/110 (55%), Gaps = 3/110 (2%)
 Frame = +3

Query: 252 MSSFWGPVTSTIECCEKNYAYSSYIAEFYNTISGLPGILLA--LIGLVNAIRQRFEKRFS 425
           MSS +   +S ++ CE N+ +S  +AEFYNT S +  ++    ++ L++   Q+  + F 
Sbjct:  10 MSSIFAYQSSEVDWCESNFQHSELVAEFYNTFSNVFFLIFGPLMMFLMHPYAQKRTRCFY 69

Query: 426 ILHISNMILAIGSMLYHATLQHVQQQSDETPMVWEILLYMYILYSPDWHY 575
            + +  M++ + SM +H TL  + Q  DE  ++W +L   Y ++ P  ++
Sbjct:  70 GVSVLFMLIGLFSMYFHMTLSFLGQLLDEISILW-LLASGYSVWLPRCYF 118

  Database: UniProt/SwissProt
    Posted date:  Sat Aug 07 14:36:18 2010
  Number of letters in database: 182,829,261
  Number of sequences in database:  518,415

Lambda     K     H
   0.267   0.041    0.140
Gapped
Lambda     K     H
   0.267   0.041    0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,378,909,851
Number of Sequences: 518415
Number of Extensions: 78378909851
Number of Successful Extensions: 523441567
Number of sequences better than 0.0: 0