BLASTX 7.6.2
Query= UN18988 /QuerySize=2411
(2410 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q05001|NCPR_CATRO NADPH--cytochrome P450 reductase OS=Cathara... 1057 7e-308
sp|P37116|NCPR_PHAAU NADPH--cytochrome P450 reductase OS=Phaseol... 933 9e-271
sp|Q3SYT8|NCPR_BOVIN NADPH--cytochrome P450 reductase OS=Bos tau... 444 2e-123
sp|Q55CT1|REDB_DICDI NADPH oxidoreductase B OS=Dictyostelium dis... 424 1e-117
sp|P37039|NCPR_CAVPO NADPH--cytochrome P450 reductase OS=Cavia p... 421 1e-116
sp|P00388|NCPR_RAT NADPH--cytochrome P450 reductase OS=Rattus no... 420 3e-116
sp|P16435|NCPR_HUMAN NADPH--cytochrome P450 reductase OS=Homo sa... 419 4e-116
sp|P04175|NCPR_PIG NADPH--cytochrome P450 reductase OS=Sus scrof... 419 4e-116
sp|P00389|NCPR_RABIT NADPH--cytochrome P450 reductase OS=Oryctol... 418 1e-115
sp|P37040|NCPR_MOUSE NADPH--cytochrome P450 reductase OS=Mus mus... 418 1e-115
sp|P19618|NCPR_SALTR NADPH--cytochrome P450 reductase (Fragments... 175 1e-042
sp|A5F3I4|CYSJ_VIBC3 Sulfite reductase [NADPH] flavoprotein alph... 169 1e-040
sp|Q87L90|CYSJ_VIBPA Sulfite reductase [NADPH] flavoprotein alph... 169 1e-040
sp|Q9KUX4|CYSJ_VIBCH Sulfite reductase [NADPH] flavoprotein alph... 167 4e-040
sp|Q8DCK2|CYSJ_VIBVU Sulfite reductase [NADPH] flavoprotein alph... 167 4e-040
sp|Q7MHA5|CYSJ_VIBVY Sulfite reductase [NADPH] flavoprotein alph... 167 5e-040
sp|Q6LM58|CYSJ_PHOPR Sulfite reductase [NADPH] flavoprotein alph... 161 2e-038
sp|Q5E841|CYSJ_VIBF1 Sulfite reductase [NADPH] flavoprotein alph... 161 4e-038
sp|O32214|CYSJ_BACSU Sulfite reductase [NADPH] flavoprotein alph... 158 2e-037
sp|Q6D1A1|CYSJ_ERWCT Sulfite reductase [NADPH] flavoprotein alph... 154 3e-036
>sp|Q05001|NCPR_CATRO NADPH--cytochrome P450 reductase OS=Catharanthus roseus
GN=CPR PE=2 SV=1
Length = 714
Score = 1057 bits (2731), Expect = 7e-308
Identities = 523/714 (73%), Positives = 614/714 (85%), Gaps = 9/714 (1%)
Frame = +2
Query: 62 SSSSSSPFDLMSAIIKGEPVVVSDPANASAYESVAAELSSMLIENRQFAMIISTSIAVLI 241
SS SPF+LMSAI+KG + S+ +++ +V+ + +ML+EN++ MI++TS+AVLI
Sbjct: 4 SSEKLSPFELMSAILKGAKLDGSNSSDSGV--AVSPAVMAMLLENKELVMILTTSVAVLI 61
Query: 242 GCIVMLVWRRSNSSGSSRRAETLKPLVIKPPREEDEVDDGRKKVTIFFGTQTGTAEGFAK 421
GC+V+L+WRRS+ SG + E K +V K E +E+D+G+KK TIFFGTQTGTAEGFAK
Sbjct: 62 GCVVVLIWRRSSGSG-KKVVEPPKLIVPKSVVEPEEIDEGKKKFTIFFGTQTGTAEGFAK 120
Query: 422 ALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFY 601
AL EEAKARYEK K++D+DDYAADD+EYEEK +KE +AFF LATYGDGEPTDNAARFY
Sbjct: 121 ALAEEAKARYEKAVIKVIDIDDYAADDEEYEEKFRKETLAFFILATYGDGEPTDNAARFY 180
Query: 602 KWFTEGDDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQ 781
KWF EG+DRG+WLKNL+YGVFGLGNRQYEHFNK+AKVVD+ + EQG +R+V + LGDDDQ
Sbjct: 181 KWFVEGNDRGDWLKNLQYGVFGLGNRQYEHFNKIAKVVDEKVAEQGGKRIVPLVLGDDDQ 240
Query: 782 CIEDDFTAWREALWPELDTILREEGDTAV-TPYTAAVLEYRVSI-HKSGDALNEKN-LAN 952
CIEDDF AWRE +WPELD +LR+E DT V T YTAA+ EYRV KS ++E N AN
Sbjct: 241 CIEDDFAAWRENVWPELDNLLRDEDDTTVSTTYTAAIPEYRVVFPDKSDSLISEANGHAN 300
Query: 953 G--NGHVVFDAQHPYRANVAVRRELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDN 1126
G NG+ V+DAQHP R+NVAVR+ELHTP SDRSCTHL+FDIAG+GL+Y TGDHVGV DN
Sbjct: 301 GYANGNTVYDAQHPCRSNVAVRKELHTPASDRSCTHLDFDIAGTGLSYGTGDHVGVYCDN 360
Query: 1127 LKETVEEALRLLDMSPDTYFSLHSDKEDGTPIS-SSLPPTFPPCSLRTALTRYACLLSSP 1303
L ETVEEA RLL++ P+TYFSLH+DKEDGTP++ SSLPP FPPC+LRTALTRYA LL++P
Sbjct: 361 LSETVEEAERLLNLPPETYFSLHADKEDGTPLAGSSLPPPFPPCTLRTALTRYADLLNTP 420
Query: 1304 KKSALLALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGV 1483
KKSALLALAA+ASDP EA+RLK+LASPAGKDEY++ +V +QRSLLEVMAEFPSAKPPLGV
Sbjct: 421 KKSALLALAAYASDPNEADRLKYLASPAGKDEYAQSLVANQRSLLEVMAEFPSAKPPLGV 480
Query: 1484 FFAAVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEK 1663
FFAA+APRLQPRFYSISSSP++A +RIHVTCALVYEK P GRIHKGVCSTWMK+A+P E+
Sbjct: 481 FFAAIAPRLQPRFYSISSSPRMAPSRIHVTCALVYEKTPGGRIHKGVCSTWMKNAIPLEE 540
Query: 1664 SENCCSAPIFVRQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVL 1843
S +C APIFVRQSNFKLP+D KVP++MIGPGTGLAPFRGFLQERLAL E G ELG +V
Sbjct: 541 SRDCSWAPIFVRQSNFKLPADPKVPVIMIGPGTGLAPFRGFLQERLALKEEGAELGTAVF 600
Query: 1844 FFGCRNRRMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ 2023
FFGCRNR+MD+IYE+EL FLE GALSEL VAFSREGPTK+YVQHKM +KASDIW MIS
Sbjct: 601 FFGCRNRKMDYIYEDELNHFLEIGALSELLVAFSREGPTKQYVQHKMAEKASDIWRMISD 660
Query: 2024 GAYVYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
GAYVYVCGDAKGMARDVHR+LHTIAQEQGSMDST+AE FVKNLQM+GRYLRDVW
Sbjct: 661 GAYVYVCGDAKGMARDVHRTLHTIAQEQGSMDSTQAEGFVKNLQMTGRYLRDVW 714
>sp|P37116|NCPR_PHAAU NADPH--cytochrome P450 reductase OS=Phaseolus aureus PE=1
SV=1
Length = 690
Score = 933 bits (2411), Expect = 9e-271
Identities = 469/671 (69%), Positives = 550/671 (81%), Gaps = 21/671 (3%)
Frame = +2
Query: 209 MIISTSIAVLIGCIVMLVWRRSNSSGSSRRAETLKPLVIKPPR-----EEDEVD--DGRK 367
+I +TS AV++G +V L W++ SS R++ +KP+V+ PR EE+EVD G+
Sbjct: 29 LIATTSAAVVVGLLVFL-WKK-----SSDRSKEVKPVVV--PRDLMMEEEEEVDVAAGKT 80
Query: 368 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 547
KVTIFFGTQTGTAEGFAKAL EE KARYEK K+VDLDDYAADDD YEEKLKKE + FF
Sbjct: 81 KVTIFFGTQTGTAEGFAKALAEEIKARYEKAAVKVVDLDDYAADDDLYEEKLKKESLVFF 140
Query: 548 FLATYGDGEPTDNAARFYKWFTEG-DDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDI 724
LATYGDGEP DNAARFYKWFTEG D+RG WL+ L YGVFGLGNRQYEHFNK+ KVVD+
Sbjct: 141 MLATYGDGEPIDNAARFYKWFTEGKDERGIWLQKLTYGVFGLGNRQYEHFNKIGKVVDEE 200
Query: 725 LVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPELDTILREEGD--TAVTPYTAAVLEY 898
L EQGA+RLV VGLGDDDQ IEDDF+AW+E+LW ELD +LR+E D T TPYTAA+LEY
Sbjct: 201 LAEQGAKRLVAVGLGDDDQSIEDDFSAWKESLWSELDQLLRDEDDANTVSTPYTAAILEY 260
Query: 899 RVSIHKSGDALNEKNLAN-GNGHVVFDAQHPYRANVAVRRELHTPESDRSCTHLEFDIAG 1075
RV IH A N + NG+ FD HP R NVAV++ELH PESDRSC HLEFDI+G
Sbjct: 261 RVVIHDPTAASTYDNHSTVANGNTEFDIHHPCRVNVAVQKELHKPESDRSCIHLEFDISG 320
Query: 1076 SGLTYETGDHVGVLSDNLKETVEEALRLLDMSPDTYFSLHSDKEDGTPISSSLPPTFP-P 1252
+ +TY+TGDHVGV ++N ETVEE +LL + D +FSLH+DK+DGT + SL P FP P
Sbjct: 321 TSITYDTGDHVGVYAENCNETVEETGKLLGQNLDLFFSLHTDKDDGTSLGGSLLPPFPGP 380
Query: 1253 CSLRTALTRYACLLSSPKKSALLALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRS 1432
CSLRTAL RYA LL+ P+K+ALLALA HAS+P++ ERLK L+SP GKDEYSKWVV SQRS
Sbjct: 381 CSLRTALARYADLLNPPRKAALLALATHASEPSD-ERLKFLSSPQGKDEYSKWVVGSQRS 439
Query: 1433 LLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRI 1612
L+EVMAEFPSAKPPLGVFFAA+APRLQPR+YSISSSP+ A R+HVTCALVY PTGRI
Sbjct: 440 LVEVMAEFPSAKPPLGVFFAAIAPRLQPRYYSISSSPRFAPQRVHVTCALVYGPTPTGRI 499
Query: 1613 HKGVCSTWMKSAVPYEKSENCCSAPIFVRQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQ 1792
HKGVCSTWMK+A+P EKS++C SAPIF+R SNFKLP D +PI+M+GPGTGLAPFRGFLQ
Sbjct: 500 HKGVCSTWMKNAIPSEKSQDCSSAPIFIRPSNFKLPVDHSIPIIMVGPGTGLAPFRGFLQ 559
Query: 1793 ERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFLESGALSELSVAFSREGPTKEYV 1972
ER AL E GV+LGP++LFFGCRNR+MDFIYE+EL+ F+E G+LSEL VAFSREG KEYV
Sbjct: 560 ERYALKEDGVQLGPALLFFGCRNRQMDFIYEDELKSFVEQGSLSELIVAFSREGAEKEYV 619
Query: 1973 QHKMMDKASDIWNMISQGAYVYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNL 2152
QHKMMDKA+ +W++ISQG Y+YVCGDAKGMARDVHR+LH+I QEQ ++DSTKAE+ VK L
Sbjct: 620 QHKMMDKAAHLWSLISQGGYLYVCGDAKGMARDVHRTLHSIVQEQENVDSTKAEAIVKKL 679
Query: 2153 QMSGRYLRDVW 2185
QM GRYLRDVW
Sbjct: 680 QMDGRYLRDVW 690
>sp|Q3SYT8|NCPR_BOVIN NADPH--cytochrome P450 reductase OS=Bos taurus GN=POR PE=2
SV=3
Length = 678
Score = 444 bits (1140), Expect = 2e-123
Identities = 246/616 (39%), Positives = 365/616 (59%), Gaps = 25/616 (4%)
Frame = +2
Query: 365 KKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 544
+ + +F+G+QTGTAE FA L ++A RY R D ++Y D +++K +A
Sbjct: 78 RNIIVFYGSQTGTAEEFANRLSKDAH-RY-GMRGMAADPEEYDLADLSSLPEIEKA-LAI 134
Query: 545 FFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDI 724
F +ATYG+G+PTDNA FY W E D L +KY VF LGN+ YEHFN + K VD
Sbjct: 135 FCMATYGEGDPTDNAQDFYDWLQETDVD---LSGVKYAVFALGNKTYEHFNAMGKYVDKR 191
Query: 725 LVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVTPYTAAVLEYRV 904
L + GAQR+ +GLGDDD +E+DF WRE WP + E T +++ +Y +
Sbjct: 192 LEQLGAQRIFDLGLGDDDGNLEEDFITWREQFWP----AVCEHFGVEATGEESSIRQYEL 247
Query: 905 SIHKSGDALNEKNLANG------NGHVVFDAQHPYRANVAVRRELHTPESDRSCTHLEFD 1066
+H D G N FDA++P+ A V R+L+ ++R HLE D
Sbjct: 248 MVHTDMDMAKVYTGEMGRLKSYENQKPPFDAKNPFLAVVTTNRKLN-QGTERHLMHLELD 306
Query: 1067 IAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSPDTYFSLHSDKEDGTPISSSLPPTF 1246
I+ S + YE+GDHV V N V + +L D SL++ E+ S+ P
Sbjct: 307 ISDSKIRYESGDHVAVYPANDSALVNQLGEILGADLDIIMSLNNLDEE----SNKKHPFP 362
Query: 1247 PPCSLRTALTRYACLLSSPKKSALLALAAHASDPTEAERLKHLASPA--GKDEYSKWVVE 1420
P S RTALT Y + + P+ + L LA +AS+PTE E+L+ +AS + GK+ Y +WV+E
Sbjct: 363 CPTSYRTALTYYLDITNPPRTNVLYELAQYASEPTEHEQLRKMASSSGEGKELYLRWVLE 422
Query: 1421 SQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMP 1600
++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K+ +H+ V +
Sbjct: 423 ARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYETK 481
Query: 1601 TGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSNFKLPSDSKVPIVMIGPGTGLAPFR 1780
TGRI+KGV ++W+++ P ++ P++VR+S F+LP + P++M+GPGTG+APF
Sbjct: 482 TGRINKGVATSWLRAKEPAGENGGRALVPMYVRKSQFRLPFKATTPVIMVGPGTGVAPFI 541
Query: 1781 GFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFLESGALSELSVAFSREGPT 1960
GF+QER L + G E+G ++L++GCR D++Y EEL F + GAL++L+VAFSRE P
Sbjct: 542 GFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAGFHKDGALTQLNVAFSREQPQ 601
Query: 1961 KEYVQHKMMDKASDIWNMISQ-GAYVYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAES 2137
K YVQH + +W +I + GA++YVCGDA+ MARDV + + I EQG+M+ +A
Sbjct: 602 KVYVQHLLKKDKEHLWKLIHEGGAHIYVCGDARNMARDVQNTFYDIVAEQGAMEHAQAVD 661
Query: 2138 FVKNLQMSGRYLRDVW 2185
+VK L GRY DVW
Sbjct: 662 YVKKLMTKGRYSLDVW 677
>sp|Q55CT1|REDB_DICDI NADPH oxidoreductase B OS=Dictyostelium discoideum GN=redB
PE=2 SV=1
Length = 667
Score = 424 bits (1090), Expect = 1e-117
Identities = 238/633 (37%), Positives = 370/633 (58%), Gaps = 36/633 (5%)
Frame = +2
Query: 326 KPPREEDEVDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDD 505
KP + + +DG+K + IFFGTQT TAE F++ + +E K ++VDL+ Y
Sbjct: 57 KPKKTITKNEDGKKVMKIFFGTQTRTAEDFSRIIEKECKK--IGIPCEVVDLESY----- 109
Query: 506 EYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLKYGVFGLGNRQY 685
E+E++L E F +AT+G+G+PTDNA FY W T + + L + + VFGLGN+ Y
Sbjct: 110 EHEQELHSESFVMFLVATHGEGDPTDNAKEFYLWLTNDERPTDLLNGVPFTVFGLGNKTY 169
Query: 686 EHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTA 865
EH+N VA+V+D + E G +R+ G GDDD +E+DF W++ +WP + L E
Sbjct: 170 EHYNAVARVIDRRMEELGGKRVFERGEGDDDATLEEDFNRWKKDMWPVVCKFLGYE--LK 227
Query: 866 VTPYTAAVLEYR-VSIHKSGDALNE----------KNLANGNGHVVFDAQHPYRANVAVR 1012
T V +R V++++ +N+ K + + V++D ++PY A V
Sbjct: 228 STEDDKFVPRFRMVTLNQDSKDINDPFIKIVSTPLKPKLSTDNKVIYDMKNPYYAEVLEN 287
Query: 1013 RELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSPDTYFSL 1192
RELH+ ESDRSC H+EF + G ++Y TGDH+GV N + VE+ ++ L ++ D +L
Sbjct: 288 RELHSNESDRSCRHIEFKL-GDEVSYTTGDHLGVFPINDSKLVEQLIKRLGVNGDDMIAL 346
Query: 1193 HSDKEDGTPISSSLPPTFPPCSLRTALTRYACLLSSPKKSALLALAAHASDPTEAERLKH 1372
++G+ I +S F P ++R A + + + + +KS L ALA ++ E +RL +
Sbjct: 347 VPIDQEGSVIKAS----FGPMTIRRAFSEHLDITNPVRKSVLRALAESTTNEEEKKRLLY 402
Query: 1373 LASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYSISSSPKIA 1552
LA+ +EY+K++ R +++++ FP + PL F PRL R YSISSSP
Sbjct: 403 LATEEANEEYNKYIKNDFRGVVDLLESFPGLQ-PLIAHFLEFTPRLPARMYSISSSPHNK 461
Query: 1553 ETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSNFKLPS--D 1726
+ +T +V R H GV STW+ +K P+FVR+S+FKLPS
Sbjct: 462 NGVVSITSVVVNFTTGNQRAHNGVASTWLSHLKVGDK------VPLFVRESHFKLPSAAT 515
Query: 1727 SKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFL 1906
+ P++M+GPGTGLAPFRGFLQE S + S+LFFGCR+ +D+IY EEL+++
Sbjct: 516 EQKPVIMVGPGTGLAPFRGFLQELQHRNHS--QQQQSLLFFGCRSDTVDYIYREELEQYH 573
Query: 1907 ESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYVCGDAKGMARDVHRSL 2086
+S L +L VAFSR+ K YVQ+K+++ +W ++++GAY YVCGD + M++ V ++L
Sbjct: 574 QSSVLGDLVVAFSRKTSQKVYVQNKLLEHKEKVWELLNKGAYFYVCGDGRNMSKAVQQAL 633
Query: 2087 HTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
+I +E GS D A+ F+ ++ GRYL+DVW
Sbjct: 634 LSIIKEFGSKDDNSAQQFIDDMSSHGRYLQDVW 666
>sp|P37039|NCPR_CAVPO NADPH--cytochrome P450 reductase OS=Cavia porcellus GN=POR
PE=2 SV=2
Length = 678
Score = 421 bits (1082), Expect = 1e-116
Identities = 234/580 (40%), Positives = 342/580 (58%), Gaps = 28/580 (4%)
Frame = +2
Query: 491 AADDDEYE----EKLKKED--VAFFFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLK 652
AAD +EY+ L + D +A F +ATYG+G+PTDNA FY W E D L +K
Sbjct: 111 AADPEEYDLADLSSLPEIDNSLAVFCMATYGEGDPTDNAQDFYDWLQETDLD---LSGVK 167
Query: 653 YGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPEL 832
Y VFGLGN+ YEHFN + K VD L + GAQR+ +GLGDDD +E+DF WRE WP +
Sbjct: 168 YAVFGLGNKTYEHFNSMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAV 227
Query: 833 DTILREEGDTAVTPYTAAVLEYRVSIHKSGDALNEKNLANG------NGHVVFDAQHPYR 994
E T +++ +Y + +H D G N FDA++P+
Sbjct: 228 CEFFGVE----ATGEESSIRQYELVLHADTDPAKVYTGEMGRLKSYENQKPPFDAKNPFL 283
Query: 995 ANVAVRRELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSP 1174
A V R+L+ ++R HLE DI+ S + YE+GDHV V N V + ++L
Sbjct: 284 AAVTTNRKLN-QGTERHLMHLELDISDSKIRYESGDHVAVYPANDSNLVNQLGKILGADL 342
Query: 1175 DTYFSLHSDKEDGTPISSSLPPTFPPCSLRTALTRYACLLSSPKKSALLALAAHASDPTE 1354
D SL + E+ S+ P P + RTALT Y + + P+ + L LA +AS+P+E
Sbjct: 343 DVVMSLKNLDEE----SNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSE 398
Query: 1355 AERLKHLASPA--GKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYS 1528
E+L +AS + GK+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YS
Sbjct: 399 QEQLHKMASSSGEGKELYLTWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYS 457
Query: 1529 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSN 1708
I+SS K+ +H+ +V + +GRI+KGV ++W+++ P ++ P+FVR+S
Sbjct: 458 IASSSKVHPNSVHICAVVVEYETKSGRINKGVATSWLQAKDPAGENGRRALVPMFVRKSQ 517
Query: 1709 FKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 1888
F+LP S P++M+GPGTG+APF GF+QER L + G E+G ++L++GCR D++Y E
Sbjct: 518 FRLPFKSTTPVIMVGPGTGVAPFIGFIQERAWLQQQGKEVGETLLYYGCRRSDEDYLYRE 577
Query: 1889 ELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYVYVCGDAKGMA 2065
EL +F + G L++L+VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA
Sbjct: 578 ELAQFHKDGTLTQLNVAFSREQAQKVYVQHLLKRDQEHLWKLIHEDGAHIYVCGDARNMA 637
Query: 2066 RDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
RDV + IA E G M+ T+A +VK L GRY DVW
Sbjct: 638 RDVQNTFCNIAAELGGMEHTQAVDYVKKLMTKGRYSLDVW 677
>sp|P00388|NCPR_RAT NADPH--cytochrome P450 reductase OS=Rattus norvegicus GN=Por
PE=1 SV=3
Length = 678
Score = 420 bits (1079), Expect = 3e-116
Identities = 242/634 (38%), Positives = 356/634 (56%), Gaps = 33/634 (5%)
Frame = +2
Query: 329 PPREEDEVDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDE 508
PP +E + KK G G EE R K + + +AD +E
Sbjct: 62 PPVKESSFVEKMKKT----GRNIIVFYGSQTGTAEEFANRLSKDAHR-YGMRGMSADPEE 116
Query: 509 YE----EKLKKED--VAFFFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLKYGVFGL 670
Y+ L + D + F +ATYG+G+PTDNA FY W E D L +K+ VFGL
Sbjct: 117 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGL 173
Query: 671 GNRQYEHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPELDTILRE 850
GN+ YEHFN + K VD L + GAQR+ +GLGDDD +E+DF WRE WP +
Sbjct: 174 GNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGV 233
Query: 851 EGDTAVTPYTAAVLEYRVSIHKSGDALNEKNLANG------NGHVVFDAQHPYRANVAVR 1012
E T +++ +Y + +H+ D G N FDA++P+ A V
Sbjct: 234 E----ATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTAN 289
Query: 1013 RELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSPDTYFSL 1192
R+L+ ++R HLE DI+ S + YE+GDHV V N V + +L D SL
Sbjct: 290 RKLN-QGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSL 348
Query: 1193 HSDKEDGTPISSSLPPTFPPCSLRTALTRYACLLSSPKKSALLALAAHASDPTEAERLKH 1372
++ E+ S+ P P + RTALT Y + + P+ + L LA +AS+P+E E L
Sbjct: 349 NNLDEE----SNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHK 404
Query: 1373 LASPA--GKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYSISSSPK 1546
+AS + GK+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K
Sbjct: 405 MASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSK 463
Query: 1547 IAETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSNFKLPSD 1726
+ +H+ V + +GR++KGV ++W+++ P ++ P+FVR+S F+LP
Sbjct: 464 VHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFK 523
Query: 1727 SKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFL 1906
S P++M+GPGTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF
Sbjct: 524 STTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFH 583
Query: 1907 ESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYVYVCGDAKGMARDVHRS 2083
+ GAL++L+VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV +
Sbjct: 584 KDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNT 643
Query: 2084 LHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
+ I E G M+ T+A +VK L GRY DVW
Sbjct: 644 FYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVW 677
>sp|P16435|NCPR_HUMAN NADPH--cytochrome P450 reductase OS=Homo sapiens GN=POR
PE=1 SV=2
Length = 677
Score = 419 bits (1077), Expect = 4e-116
Identities = 231/579 (39%), Positives = 339/579 (58%), Gaps = 27/579 (4%)
Frame = +2
Query: 491 AADDDEYE----EKLKKEDVAF--FFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLK 652
+AD +EY+ L + D A F +ATYG+G+PTDNA FY W E D L +K
Sbjct: 111 SADPEEYDLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LSGVK 167
Query: 653 YGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPEL 832
+ VFGLGN+ YEHFN + K VD L + GAQR+ +GLGDDD +E+DF WRE WP
Sbjct: 168 FAVFGLGNKTYEHFNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWP-- 225
Query: 833 DTILREEGDTAVTPYTAAVLEYRVSIHKSGDALNEKNLANG------NGHVVFDAQHPYR 994
+ E T +++ +Y + +H DA G N FDA++P+
Sbjct: 226 --AVCEHFGVEATGEESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFL 283
Query: 995 ANVAVRRELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSP 1174
A V R+L+ ++R HLE DI+ S + YE+GDHV V N V + ++L
Sbjct: 284 AAVTTNRKLN-QGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADL 342
Query: 1175 DTYFSLHSDKEDGTPISSSLPPTFPPCSLRTALTRYACLLSSPKKSALLALAAHASDPTE 1354
D SL++ E+ S+ P P S RTALT Y + + P+ + L LA +AS+P+E
Sbjct: 343 DVVMSLNNLDEE----SNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSE 398
Query: 1355 AERLKHLASPA--GKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYS 1528
E L+ +AS + GK+ Y WVVE++R +L ++ + PS +PP+ + PRLQ R+YS
Sbjct: 399 QELLRKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPID-HLCELLPRLQARYYS 457
Query: 1529 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSN 1708
I+SS K+ +H+ +V + GRI+KGV + W+++ P ++ P+FVR+S
Sbjct: 458 IASSSKVHPNSVHICAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQ 517
Query: 1709 FKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 1888
F+LP + P++M+GPGTG+APF GF+QER L + G E+G ++L++GCR D++Y E
Sbjct: 518 FRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYRE 577
Query: 1889 ELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYVCGDAKGMAR 2068
EL +F GAL++L+VAFSRE K YVQH + +W +I GA++YVCGDA+ MAR
Sbjct: 578 ELAQFHRDGALTQLNVAFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMAR 637
Query: 2069 DVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
DV + + I E G+M+ +A ++K L GRY DVW
Sbjct: 638 DVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYSLDVW 676
>sp|P04175|NCPR_PIG NADPH--cytochrome P450 reductase OS=Sus scrofa GN=POR PE=1
SV=2
Length = 678
Score = 419 bits (1077), Expect = 4e-116
Identities = 233/580 (40%), Positives = 340/580 (58%), Gaps = 28/580 (4%)
Frame = +2
Query: 491 AADDDEYE----EKLKKED--VAFFFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLK 652
AAD +EY+ L + + +A F +ATYG+G+PTDNA FY W E D L +K
Sbjct: 111 AADPEEYDLSDLSSLPEIENALAVFCMATYGEGDPTDNAQDFYDWLQEADVD---LTGVK 167
Query: 653 YGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPEL 832
Y VFGLGN+ YEHFN + K VD L + GAQR+ +GLGDDD +E+DF WRE WP
Sbjct: 168 YAVFGLGNKTYEHFNAMGKYVDKRLEQLGAQRIFDLGLGDDDGNLEEDFITWREQFWP-- 225
Query: 833 DTILREEGDTAVTPYTAAVLEYRVSIHKSGDALNEKNLANG------NGHVVFDAQHPYR 994
+ E T +++ +Y + +H D G N FDA++P+
Sbjct: 226 --AVCEHFGVEATGEESSIRQYELVVHTDMDTAVVYTGEMGRLKSYENQKPPFDAKNPFL 283
Query: 995 ANVAVRRELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSP 1174
A V R+L+ ++R HLE DI+ S + YE+GDHV V N V + +L
Sbjct: 284 AVVTTNRKLN-QGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGEILGTDL 342
Query: 1175 DTYFSLHSDKEDGTPISSSLPPTFPPCSLRTALTRYACLLSSPKKSALLALAAHASDPTE 1354
D SL++ E+ S+ P P + RTALT Y + + P+ + L LA +AS+P+E
Sbjct: 343 DIVMSLNNLDEE----SNKRHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSE 398
Query: 1355 AERLKHLASPA--GKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYS 1528
E+L+ +AS + GK+ Y WVVE++R +L ++ ++PS +PP+ PRLQ R+YS
Sbjct: 399 QEQLRKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPID-HLCERLPRLQARYYS 457
Query: 1529 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSN 1708
I+SS K+ +H+ +V + +GR++KGV ++W+++ P ++ P+FVR+S
Sbjct: 458 IASSSKVHPNSVHICAVVVEYETKSGRVNKGVATSWLRAKEPAGENGRRALVPMFVRKSQ 517
Query: 1709 FKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 1888
F+LP + P++M+GPGTG+APF GF+QER L E G E+G ++L++GCR D++Y E
Sbjct: 518 FRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLQEQGKEVGETLLYYGCRRSDEDYLYRE 577
Query: 1889 ELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYVYVCGDAKGMA 2065
EL +F GAL+ LSVAFSRE P K YVQH + +W +I GA++Y+CGDA+ MA
Sbjct: 578 ELAQFHAKGALTRLSVAFSREQPQKVYVQHLLKRDKEHLWKLIHDGGAHIYICGDARNMA 637
Query: 2066 RDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
RDV + I EQG M+ +A +VK L GRY DVW
Sbjct: 638 RDVQNTFCDIVAEQGPMEHAQAVDYVKKLMTKGRYSLDVW 677
>sp|P00389|NCPR_RABIT NADPH--cytochrome P450 reductase OS=Oryctolagus cuniculus
GN=POR PE=1 SV=1
Length = 679
Score = 418 bits (1074), Expect = 1e-115
Identities = 230/580 (39%), Positives = 338/580 (58%), Gaps = 28/580 (4%)
Frame = +2
Query: 491 AADDDEYE----EKLKK--EDVAFFFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLK 652
AAD +EY+ L + +A F +ATYG+G+PTDNA FY W E D L +K
Sbjct: 112 AADPEEYDLADLSSLPEINNALAVFCMATYGEGDPTDNAQDFYDWLQETDVD---LSGVK 168
Query: 653 YGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPEL 832
Y VFGLGN+ YEHFN + K VD L + GAQR+ +G+GDDD +E+DF WRE WP
Sbjct: 169 YAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGMGDDDANLEEDFITWREQFWP-- 226
Query: 833 DTILREEGDTAVTPYTAAVLEYRVSIHKSGDALNEKNLANG------NGHVVFDAQHPYR 994
+ E T +++ +Y + +H D G N FDA++P+
Sbjct: 227 --AVCEHFGVEATGEESSIRQYELVLHTDIDVAKVYQGEMGRLKSYENQKPPFDAKNPFL 284
Query: 995 ANVAVRRELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSP 1174
A V R+L+ ++R HLE DI+ S + YE+GDHV V N V + +L
Sbjct: 285 ATVTTNRKLN-QGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGEILGADL 343
Query: 1175 DTYFSLHSDKEDGTPISSSLPPTFPPCSLRTALTRYACLLSSPKKSALLALAAHASDPTE 1354
D SL++ E+ S+ P P S RTALT Y + + P+ + L LA +A+DP E
Sbjct: 344 DVVMSLNNLDEE----SNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYAADPAE 399
Query: 1355 AERLKHLASPA--GKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYS 1528
E+L+ +AS + GK+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YS
Sbjct: 400 QEQLRKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYS 458
Query: 1529 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSN 1708
I+SS K+ +H+ V + GR++KGV ++W+++ P ++ P+FVR+S
Sbjct: 459 IASSSKVHPNSVHICAVAVEYETKAGRLNKGVATSWLRAKEPAGENGGRALVPMFVRKSQ 518
Query: 1709 FKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 1888
F+LP + P++M+GPGTG+APF GF+QER L + G E+G ++L++GCR D++Y E
Sbjct: 519 FRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRAAEDYLYRE 578
Query: 1889 ELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYVYVCGDAKGMA 2065
EL F + G LS+L+VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA
Sbjct: 579 ELAGFQKDGTLSQLNVAFSREQAQKVYVQHLLRRDKEHLWRLIHEGGAHIYVCGDARNMA 638
Query: 2066 RDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
RDV + + I E G+M+ +A +VK L GRY DVW
Sbjct: 639 RDVQNTFYDIVAELGAMEHAQAVDYVKKLMTKGRYSLDVW 678
>sp|P37040|NCPR_MOUSE NADPH--cytochrome P450 reductase OS=Mus musculus GN=Por
PE=1 SV=2
Length = 678
Score = 418 bits (1073), Expect = 1e-115
Identities = 241/634 (38%), Positives = 355/634 (55%), Gaps = 33/634 (5%)
Frame = +2
Query: 329 PPREEDEVDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDE 508
PP +E + KK G G EE R K + + +AD +E
Sbjct: 62 PPVKESSFVEKMKKT----GRNIIVFYGSQTGTAEEFANRLSKDAHR-YGMRGMSADPEE 116
Query: 509 YE----EKLKKED--VAFFFLATYGDGEPTDNAARFYKWFTEGDDRGEWLKNLKYGVFGL 670
Y+ L + D + F +ATYG+G+PTDNA FY W E D L +K+ VFGL
Sbjct: 117 YDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGL 173
Query: 671 GNRQYEHFNKVAKVVDDILVEQGAQRLVHVGLGDDDQCIEDDFTAWREALWPELDTILRE 850
GN+ YEHFN + K VD L + GAQR+ +GLGDDD +E+DF WRE WP +
Sbjct: 174 GNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGV 233
Query: 851 EGDTAVTPYTAAVLEYRVSIHKSGDALNEKNLANG------NGHVVFDAQHPYRANVAVR 1012
E T +++ +Y + +H+ D G N FDA++P+ A V
Sbjct: 234 E----ATGEESSIRQYELVVHEDMDTAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTTN 289
Query: 1013 RELHTPESDRSCTHLEFDIAGSGLTYETGDHVGVLSDNLKETVEEALRLLDMSPDTYFSL 1192
R+L+ ++R HLE DI+ S + YE+GDHV V N V + +L D SL
Sbjct: 290 RKLN-QGTERHLMHLELDISDSKIRYESGDHVAVYPANDSTLVNQIGEILGADLDVIMSL 348
Query: 1193 HSDKEDGTPISSSLPPTFPPCSLRTALTRYACLLSSPKKSALLALAAHASDPTEAERLKH 1372
++ E+ S+ P P + RTALT Y + + P+ + L LA +AS+P+E E L
Sbjct: 349 NNLDEE----SNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHK 404
Query: 1373 LASPA--GKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAAVAPRLQPRFYSISSSPK 1546
+AS + GK+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K
Sbjct: 405 MASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSK 463
Query: 1547 IAETRIHVTCALVYEKMPTGRIHKGVCSTWMKSAVPYEKSENCCSAPIFVRQSNFKLPSD 1726
+ +H+ V + +GR++KGV ++W+++ P ++ P+FVR+S F+LP
Sbjct: 464 VHPNSVHICAVAVEYEAKSGRVNKGVATSWLRTKEPAGENGRRALVPMFVRKSQFRLPFK 523
Query: 1727 SKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFL 1906
P++M+GPGTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF
Sbjct: 524 PTTPVIMVGPGTGVAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFH 583
Query: 1907 ESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYVYVCGDAKGMARDVHRS 2083
+ GAL++L+VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV +
Sbjct: 584 KDGALTQLNVAFSREQAHKVYVQHLLKRDKEHLWKLIHEGGAHIYVCGDARNMAKDVQNT 643
Query: 2084 LHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
+ I E G M+ T+A +VK L GRY DVW
Sbjct: 644 FYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVW 677
>sp|P19618|NCPR_SALTR NADPH--cytochrome P450 reductase (Fragments) OS=Salmo
trutta PE=1 SV=1
Length = 601
Score = 175 bits (443), Expect = 1e-042
Identities = 80/166 (48%), Positives = 118/166 (71%), Gaps = 1/166 (0%)
Frame = +2
Query: 1691 FVRQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRM 1870
++R+S F+LP + P++M+GPGTG+APF GF+QER L ESG E+G +VL+ GCR++
Sbjct: 435 YIRKSQFRLPFKASNPVIMVGPGTGIAPFMGFIQERGWLKESGKEVGETVLYCGCRHKEE 494
Query: 1871 DFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQG-AYVYVCG 2047
D++Y+EEL++ + GAL++L+VAFSRE K YVQH + D+W I + A++Y+CG
Sbjct: 495 DYLYQEELEQAHKKGALTKLNVAFSREQDQKVYVQHLLRKNKVDLWRQIHEDYAHIYICG 554
Query: 2048 DAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
DA+ MARDV + + IA+E G M T+A ++K L GRY +DVW
Sbjct: 555 DARNMARDVQTAFYEIAEELGGMTRTQATDYIKKLMTKGRYSQDVW 600
>sp|A5F3I4|CYSJ_VIBC3 Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Ogawa 395 / O395)
GN=cysJ PE=3 SV=1
Length = 614
Score = 169 bits (426), Expect = 1e-040
Identities = 81/171 (47%), Positives = 117/171 (68%), Gaps = 7/171 (4%)
Frame = +2
Query: 1682 APIFV---RQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFG 1852
AP+ V +NFKLPSD P++M+GPGTG+APFR F+QER E+ G + L FG
Sbjct: 448 APVKVFVEHNNNFKLPSDDNAPLIMVGPGTGIAPFRSFIQER----ENRGAAGKNWLLFG 503
Query: 1853 CRNRRMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAY 2032
R DF+Y+ E Q++L+SG L+ L VAFSR+ K YVQH+++D+A +W + +GAY
Sbjct: 504 DRTFTQDFLYQVEWQKYLKSGVLNRLDVAFSRDQHEKVYVQHRLLDQAELVWQWLQEGAY 563
Query: 2033 VYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
YVCGDA MA+DVH++L T+ ++QG ++ +AE +V L+ + RY RDV+
Sbjct: 564 FYVCGDASRMAKDVHQALITVVEQQGGLNREQAEEYVSELRKAKRYQRDVY 614
>sp|Q87L90|CYSJ_VIBPA Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Vibrio parahaemolyticus GN=cysJ PE=3 SV=1
Length = 623
Score = 169 bits (426), Expect = 1e-040
Identities = 82/167 (49%), Positives = 114/167 (68%), Gaps = 5/167 (2%)
Frame = +2
Query: 1688 IFV-RQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNR 1864
+FV +NFKLP D PI+M+GPGTG+APFR F+QER E+ G + LFFG R
Sbjct: 461 VFVEHNNNFKLPEDDTTPIIMVGPGTGIAPFRSFIQER----ENRDAEGKNWLFFGDRTF 516
Query: 1865 RMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYVC 2044
DF+Y+ E Q++L+SG LS L VAFSR+ K YVQH++++ A+ +W I GAY+YVC
Sbjct: 517 TQDFLYQVEWQKYLKSGVLSRLDVAFSRDQVEKVYVQHRILENAAQVWQWIQDGAYIYVC 576
Query: 2045 GDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
GDA MA+DVH +L +A+++G M AE F+ +L+ + RY RDV+
Sbjct: 577 GDATRMAKDVHDALVIVAEQEGKMPRDDAEQFINDLRKAKRYQRDVY 623
>sp|Q9KUX4|CYSJ_VIBCH Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Vibrio cholerae GN=cysJ PE=3 SV=1
Length = 614
Score = 167 bits (422), Expect = 4e-040
Identities = 80/171 (46%), Positives = 117/171 (68%), Gaps = 7/171 (4%)
Frame = +2
Query: 1682 APIFV---RQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFG 1852
AP+ V +NFKLPSD P++M+GPGTG+APFR F+QER E+ G + L FG
Sbjct: 448 APVKVFVEHNNNFKLPSDDNAPLIMVGPGTGIAPFRSFIQER----ENRGAAGKNWLLFG 503
Query: 1853 CRNRRMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAY 2032
R DF+Y+ E Q++L+SG L+ L VAFSR+ K YVQH+++++A +W + +GAY
Sbjct: 504 DRTFTQDFLYQVEWQKYLKSGVLNRLDVAFSRDQHEKVYVQHRLLEQAELVWQWLQEGAY 563
Query: 2033 VYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
YVCGDA MA+DVH++L T+ ++QG ++ +AE +V L+ + RY RDV+
Sbjct: 564 FYVCGDASRMAKDVHQALITVVEQQGGLNREQAEEYVSELRKAKRYQRDVY 614
>sp|Q8DCK2|CYSJ_VIBVU Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Vibrio vulnificus GN=cysJ PE=3 SV=1
Length = 616
Score = 167 bits (422), Expect = 4e-040
Identities = 80/167 (47%), Positives = 117/167 (70%), Gaps = 5/167 (2%)
Frame = +2
Query: 1688 IFV-RQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNR 1864
+FV +NFKLP+D VP++M+GPGTG+APFR F+QER G E G + LFFG R
Sbjct: 454 VFVENNNNFKLPADDNVPVIMVGPGTGIAPFRSFIQER---DNRGAE-GKNWLFFGDRTF 509
Query: 1865 RMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYVC 2044
DF+Y+ E Q++L+SG L++L VAFSR+ K YVQ ++++ A+ +W I +GAY+YVC
Sbjct: 510 TQDFLYQVEWQKYLKSGLLTKLDVAFSRDQAEKVYVQQRILENAAQVWQWIQEGAYLYVC 569
Query: 2045 GDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
GDA MA+DVH++ +A+++G M AE F+ +L+ + RY RDV+
Sbjct: 570 GDANRMAKDVHQAFVAVAEQEGKMSRDDAEEFINDLRKAKRYQRDVY 616
>sp|Q7MHA5|CYSJ_VIBVY Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Vibrio vulnificus (strain YJ016) GN=cysJ PE=3 SV=2
Length = 616
Score = 167 bits (421), Expect = 5e-040
Identities = 80/167 (47%), Positives = 117/167 (70%), Gaps = 5/167 (2%)
Frame = +2
Query: 1688 IFV-RQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNR 1864
+FV +NFKLP+D VP++M+GPGTG+APFR F+QER G E G + LFFG R
Sbjct: 454 VFVENNNNFKLPADDNVPVIMVGPGTGIAPFRSFIQER---DNRGAE-GKNWLFFGDRTF 509
Query: 1865 RMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYVC 2044
DF+Y+ E Q++L+SG L++L VAFSR+ K YVQ ++++ A+ +W I +GAY+YVC
Sbjct: 510 TQDFLYQVEWQKYLKSGLLTKLDVAFSRDQAEKVYVQQRILENAAQVWQWIQEGAYLYVC 569
Query: 2045 GDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
GDA MA+DVH++ +A+++G M AE F+ +L+ + RY RDV+
Sbjct: 570 GDANRMAKDVHQAFVAVAEQEGKMSRGDAEEFINDLRKAKRYQRDVY 616
>sp|Q6LM58|CYSJ_PHOPR Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Photobacterium profundum GN=cysJ PE=3 SV=1
Length = 605
Score = 161 bits (407), Expect = 2e-038
Identities = 77/174 (44%), Positives = 116/174 (66%), Gaps = 5/174 (2%)
Frame = +2
Query: 1667 ENCCSAPIFVRQ-SNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVL 1843
E + +FV + +NFKLP+D P++MIGPGTG+APFR F+QER ++ G + L
Sbjct: 436 EEGAAVKVFVEENNNFKLPADDNTPVIMIGPGTGIAPFRAFVQER----DNREAEGKNWL 491
Query: 1844 FFGCRNRRMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQ 2023
FFG R DF+Y+ E Q++L+SG + +L VAFSR+ K YVQH++++ A +W + +
Sbjct: 492 FFGDRTFTDDFLYQVEWQKYLKSGVVQQLDVAFSRDQVEKVYVQHRVLEHAEQVWQWLQE 551
Query: 2024 GAYVYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
GA+VYVCGD MA+DVH +L T+ ++QG +AE ++ L+ S RY +DV+
Sbjct: 552 GAHVYVCGDMNHMAKDVHDALLTVIEQQGKQSREQAEQYLNELRKSKRYQKDVY 605
>sp|Q5E841|CYSJ_VIBF1 Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=cysJ PE=3 SV=1
Length = 604
Score = 161 bits (405), Expect = 4e-038
Identities = 77/167 (46%), Positives = 112/167 (67%), Gaps = 5/167 (2%)
Frame = +2
Query: 1688 IFV-RQSNFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNR 1864
+FV +NFKLP D P++MIGPGTG+APFR F+QER ++ G + LFFG R
Sbjct: 442 VFVEHNNNFKLPQDDNAPVIMIGPGTGIAPFRSFVQER----DNRDAEGKNWLFFGDRIF 497
Query: 1865 RMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYVC 2044
DF+Y+ E Q++L+SG +++L VAFSR+ K YVQH++++ A+ +W + GAY+YVC
Sbjct: 498 TQDFLYQVEWQKYLKSGIVNQLDVAFSRDQQEKVYVQHRILEHAAQVWQWLQDGAYIYVC 557
Query: 2045 GDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
GDA MA+DVH +L + ++ G +AE FV L+ + RY RDV+
Sbjct: 558 GDATRMAKDVHEALICVVEQHGQKTREEAEQFVNELRKAKRYQRDVY 604
>sp|O32214|CYSJ_BACSU Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Bacillus subtilis GN=cysJ PE=1 SV=1
Length = 605
Score = 158 bits (399), Expect = 2e-037
Identities = 75/168 (44%), Positives = 120/168 (71%), Gaps = 5/168 (2%)
Frame = +2
Query: 1685 PIFVRQS-NFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRN 1861
P++V+ + NFKLP D + PI+M+GPGTG+APFR F+QER E+G E G + +FFG ++
Sbjct: 442 PVYVQHNQNFKLPKDPETPIIMVGPGTGVAPFRSFMQER---EETGAE-GKAWMFFGDQH 497
Query: 1862 RRMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYV 2041
DF+Y+ E Q +L+ G L+++ VAFSR+ K YVQH+M++ +++++ + +GA VY+
Sbjct: 498 FVTDFLYQTEWQNWLKDGVLTKMDVAFSRDTEEKVYVQHRMLEHSAELFEWLQEGAAVYI 557
Query: 2042 CGDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
CGD K MA DVH +L I +++G+M +AE+++ ++Q RY RDV+
Sbjct: 558 CGDEKHMAHDVHNTLLEIIEKEGNMSREEAEAYLADMQQQKRYQRDVY 605
>sp|Q6D1A1|CYSJ_ERWCT Sulfite reductase [NADPH] flavoprotein alpha-component
OS=Erwinia carotovora subsp. atroseptica GN=cysJ PE=3 SV=1
Length = 609
Score = 154 bits (388), Expect = 3e-036
Identities = 75/167 (44%), Positives = 116/167 (69%), Gaps = 5/167 (2%)
Frame = +2
Query: 1688 IFVRQS-NFKLPSDSKVPIVMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNR 1864
+F+ + NF+LP++S+ P++MIGPGTG+APFR F+Q+R A G E G + LFFG +
Sbjct: 447 VFIEHNDNFRLPANSETPVIMIGPGTGIAPFRAFMQQRDA---DGAE-GKNWLFFGNPHF 502
Query: 1865 RMDFIYEEELQRFLESGALSELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYVYVC 2044
DF+Y+ E QR+++ G L+ + +A+SR+ K YVQ K+ +K +++W I GA++YVC
Sbjct: 503 TEDFLYQVEWQRYVKEGLLTHIDLAWSRDQAHKIYVQDKLREKGAEVWRWIQDGAHLYVC 562
Query: 2045 GDAKGMARDVHRSLHTIAQEQGSMDSTKAESFVKNLQMSGRYLRDVW 2185
GDA MA+DV R+L + E G MDS +A+ F+ +L++ RY RDV+
Sbjct: 563 GDANRMAKDVERALLDVIVEHGGMDSEQADEFLSDLRLERRYQRDVY 609
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,378,909,851
Number of Sequences: 518415
Number of Extensions: 78378909851
Number of Successful Extensions: 523441567
Number of sequences better than 0.0: 0
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