BLASTX 7.6.2
Query= UN19105 /QuerySize=802
(801 letters)
Database: UniProt/TrEMBL;
11,397,958 sequences; 3,661,877,547 total letters
Score E
Sequences producing significant alignments: (bits) Value
tr|Q3EAG8|Q3EAG8_ARATH Methylenetetrahydrofolate reductase OS=Ar... 439 2e-121
tr|A5ATB7|A5ATB7_VITVI Methylenetetrahydrofolate reductase OS=Vi... 419 2e-115
tr|C5WVY7|C5WVY7_SORBI Methylenetetrahydrofolate reductase OS=So... 414 6e-114
tr|B9HG95|B9HG95_POPTR Methylenetetrahydrofolate reductase OS=Po... 408 5e-112
tr|B9STA4|B9STA4_RICCO Methylenetetrahydrofolate reductase OS=Ri... 406 2e-111
tr|C6T731|C6T731_SOYBN Methylenetetrahydrofolate reductase OS=Gl... 406 2e-111
tr|B8LKP0|B8LKP0_PICSI Methylenetetrahydrofolate reductase OS=Pi... 404 5e-111
tr|B9N8L0|B9N8L0_POPTR Methylenetetrahydrofolate reductase OS=Po... 403 1e-110
tr|A2XNC0|A2XNC0_ORYSI Methylenetetrahydrofolate reductase OS=Or... 403 1e-110
tr|Q10BJ6|Q10BJ6_ORYSJ Methylenetetrahydrofolate reductase OS=Or... 403 1e-110
tr|Q10BJ7|Q10BJ7_ORYSJ Methylenetetrahydrofolate reductase OS=Or... 403 1e-110
tr|A9RW65|A9RW65_PHYPA Methylenetetrahydrofolate reductase OS=Ph... 381 5e-104
tr|A9U4S7|A9U4S7_PHYPA Methylenetetrahydrofolate reductase OS=Ph... 380 1e-103
tr|A6XMY8|A6XMY8_TRIMO Methylenetetrahydrofolate reductase OS=Tr... 371 8e-101
tr|A8IAY6|A8IAY6_CHLRE Methylenetetrahydrofolate reductase OS=Ch... 315 5e-084
tr|B8BVS6|B8BVS6_THAPS Methylenetetrahydrofolate reductase OS=Th... 247 2e-063
tr|D2V2R1|D2V2R1_NAEGR Methylenetetrahydrofolate reductase OS=Na... 193 2e-047
tr|A9UZU5|A9UZU5_MONBE Methylenetetrahydrofolate reductase OS=Mo... 190 2e-046
tr|B0CU22|B0CU22_LACBS Methylenetetrahydrofolate reductase OS=La... 180 2e-043
tr|Q4P5K1|Q4P5K1_USTMA Methylenetetrahydrofolate reductase OS=Us... 177 2e-042
>tr|Q3EAG8|Q3EAG8_ARATH Methylenetetrahydrofolate reductase OS=Arabidopsis
thaliana GN=At3g59970 PE=3 SV=1
Length = 407
Score = 439 bits (1127), Expect = 2e-121
Identities = 204/240 (85%), Positives = 226/240 (94%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKVVDKIKS T++G+T FSFEFFPP+TEDGV+NLFERMDRLV+YGP FCDITWGAGG+TA
Sbjct: 1 MKVVDKIKSVTEQGQTAFSFEFFPPKTEDGVENLFERMDRLVSYGPTFCDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
DLTL+I SRMQNV+CVE+MMHLTCTNMP+EKIDHALETIRSNGIQNVLALRGDPPHG++K
Sbjct: 61 DLTLEIASRMQNVICVETMMHLTCTNMPIEKIDHALETIRSNGIQNVLALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FVQVEGGF CALDLVNHIRSKYGDYFG+ VAGYPEAHPDVI +GLA+ E+Y+SDL YLK
Sbjct: 121 FVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
KKVDAGADLIVTQLF+DTDI LKFVNDCRQIGI CPIVPGIMPI+NYKGFLRM GFC+ +
Sbjct: 181 KKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTK 240
>tr|A5ATB7|A5ATB7_VITVI Methylenetetrahydrofolate reductase OS=Vitis vinifera
GN=VITISV_016119 PE=3 SV=1
Length = 594
Score = 419 bits (1076), Expect = 2e-115
Identities = 195/241 (80%), Positives = 225/241 (93%), Gaps = 2/241 (0%)
Frame = +2
Query: 41 MKVVDKIK-SWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTT 217
MKV++KI+ + T+EGK FSFEFFPP+TEDGVDNLFERMDR+VA+GPAFCDITWGAGG+T
Sbjct: 1 MKVIEKIRDAATEEGKVVFSFEFFPPKTEDGVDNLFERMDRMVAHGPAFCDITWGAGGST 60
Query: 218 ADLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGEN 397
ADLTL+I ++MQN++CVE+MMHLTCTNMPVEKIDHAL+TI+SNGIQNVLALRGDPPHG++
Sbjct: 61 ADLTLEISNKMQNMICVETMMHLTCTNMPVEKIDHALDTIKSNGIQNVLALRGDPPHGQD 120
Query: 398 KFVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYL 577
KFVQ++GGF CALDLV HIR+KYGDYFG+ VAGYPEAHPDVI NG+A+ EAY+SDL YL
Sbjct: 121 KFVQIQGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDVI-LNGVATSEAYQSDLAYL 179
Query: 578 KKKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRP 757
K+KVDAGADLIVTQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGFLRM GFC+
Sbjct: 180 KRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKT 239
Query: 758 R 760
+
Sbjct: 240 K 240
>tr|C5WVY7|C5WVY7_SORBI Methylenetetrahydrofolate reductase OS=Sorghum bicolor
GN=Sb01g003700 PE=3 SV=1
Length = 593
Score = 414 bits (1063), Expect = 6e-114
Identities = 191/240 (79%), Positives = 218/240 (90%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKV++KI+ G+T FSFE+FPP+TE+GV+NLFERMDR+VA+GP+FCDITWGAGG+TA
Sbjct: 1 MKVIEKIQEAAGNGRTAFSFEYFPPKTEEGVENLFERMDRMVAHGPSFCDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
DLTL+I +RMQN+VCVE+MMHLTCTNMPVEKIDHALETI+SNGIQNVLALRGDPPHG++K
Sbjct: 61 DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FVQVEGGF CALDLV HIR+KYGDYFG+ VAGYPEAHPD I G A+ EAY +DL YLK
Sbjct: 121 FVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
+KVDAGADLIVTQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGFLRM GFC+ +
Sbjct: 181 RKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK 240
>tr|B9HG95|B9HG95_POPTR Methylenetetrahydrofolate reductase OS=Populus
trichocarpa GN=MTHFR1 PE=3 SV=1
Length = 608
Score = 408 bits (1047), Expect = 5e-112
Identities = 185/230 (80%), Positives = 209/230 (90%)
Frame = +2
Query: 71 TDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTADLTLDIVSRM 250
+ K FSFEFFPP+TEDGVDNLFERMDR+VA+ P+FCDITWGAGG+TADLTLDI ++M
Sbjct: 25 SSSNKVVFSFEFFPPKTEDGVDNLFERMDRMVAHNPSFCDITWGAGGSTADLTLDIANKM 84
Query: 251 QNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENKFVQVEGGFGC 430
QN++CVE+MMHLTCTNMPVEKIDHALETI+SNGIQNVLALRGDPPHG++KFVQ++GGF C
Sbjct: 85 QNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQIQGGFAC 144
Query: 431 ALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLKKKVDAGADLI 610
ALDLV HIRSKYGDYFG+ VAGYPEAHPD IG +G A+ E Y+ DL YLK+KVDAGADLI
Sbjct: 145 ALDLVKHIRSKYGDYFGITVAGYPEAHPDAIGSDGFATPEDYQKDLAYLKQKVDAGADLI 204
Query: 611 VTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
VTQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGFLRM GFC+ +
Sbjct: 205 VTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK 254
>tr|B9STA4|B9STA4_RICCO Methylenetetrahydrofolate reductase OS=Ricinus communis
GN=RCOM_0364940 PE=3 SV=1
Length = 609
Score = 406 bits (1041), Expect = 2e-111
Identities = 184/226 (81%), Positives = 209/226 (92%)
Frame = +2
Query: 83 KTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTADLTLDIVSRMQNVV 262
K FSFEFFPP+TEDGVDNLF+RMDR+V++ P FCDITWGAGG+TADLTLDI ++MQN++
Sbjct: 30 KVVFSFEFFPPKTEDGVDNLFDRMDRMVSHNPTFCDITWGAGGSTADLTLDIANKMQNMI 89
Query: 263 CVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENKFVQVEGGFGCALDL 442
CVE+MMHLTCTNMPVEKIDHAL+TI+SNGIQNVLALRGDPPHG++KFVQVEGGF CALDL
Sbjct: 90 CVETMMHLTCTNMPVEKIDHALQTIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDL 149
Query: 443 VNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLKKKVDAGADLIVTQL 622
V HIRSKYGDYFG+ VAGYPEAHPD+I +GLA+ E Y+ DLEYLK+KVDAGADLI+TQL
Sbjct: 150 VKHIRSKYGDYFGITVAGYPEAHPDMIESDGLATPENYQRDLEYLKRKVDAGADLIITQL 209
Query: 623 FFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
F+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGFLRM GFC+ +
Sbjct: 210 FYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFLRMTGFCKTK 255
>tr|C6T731|C6T731_SOYBN Methylenetetrahydrofolate reductase OS=Glycine max PE=2
SV=1
Length = 344
Score = 406 bits (1041), Expect = 2e-111
Identities = 186/241 (77%), Positives = 215/241 (89%), Gaps = 1/241 (0%)
Frame = +2
Query: 41 MKVVDKIKSWT-DEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTT 217
MK+++KI + + D + FSFEFFPP+TEDGVDNLFERMDR+V + P+FCDITW AGGTT
Sbjct: 1 MKIIEKIHAASADPNRVVFSFEFFPPKTEDGVDNLFERMDRMVVHNPSFCDITWSAGGTT 60
Query: 218 ADLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGEN 397
ADLTL+I ++MQN+VCVE+MMHLTCTNMPVEKIDHAL TI+SNG+QNVLALRGDPPHG++
Sbjct: 61 ADLTLEIANKMQNIVCVETMMHLTCTNMPVEKIDHALHTIKSNGLQNVLALRGDPPHGQD 120
Query: 398 KFVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYL 577
KFVQVEGGF CA DLV HIR+KYGDYFG+ VAGYPEAHPDVI +GLA+ E Y++DL YL
Sbjct: 121 KFVQVEGGFACARDLVQHIRAKYGDYFGITVAGYPEAHPDVIESDGLATSEGYQNDLAYL 180
Query: 578 KKKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRP 757
K KVDAGADLIVTQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGF+RM GFC+
Sbjct: 181 KSKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFIRMTGFCKT 240
Query: 758 R 760
+
Sbjct: 241 K 241
>tr|B8LKP0|B8LKP0_PICSI Methylenetetrahydrofolate reductase OS=Picea sitchensis
PE=2 SV=1
Length = 594
Score = 404 bits (1038), Expect = 5e-111
Identities = 186/240 (77%), Positives = 216/240 (90%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKV++KI++ EGK FSFEFFPP+TE+GV+NLF+RMDR+V + P+FCDITWGAGG+TA
Sbjct: 1 MKVIEKIQNAEKEGKVVFSFEFFPPKTEEGVENLFDRMDRMVEHQPSFCDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
DLTLDI ++MQN++CVESMMHLTCTNMPVEKIDHAL TI++NGIQNVLALRGDPPHG++K
Sbjct: 61 DLTLDISNKMQNMICVESMMHLTCTNMPVEKIDHALATIKANGIQNVLALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FVQVEGGF CALDLV HIRSKYGDYFG+ VAGYPEAHPD+I A++E Y+ DL YLK
Sbjct: 121 FVQVEGGFACALDLVKHIRSKYGDYFGITVAGYPEAHPDMIKNEVGATEEDYQKDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
KVDAGADLI+TQLF+DTDI LKFVNDCRQIGIKCPIVPGIMPINNYKGF+RM GFC+ +
Sbjct: 181 LKVDAGADLIITQLFYDTDIYLKFVNDCRQIGIKCPIVPGIMPINNYKGFIRMAGFCKTK 240
>tr|B9N8L0|B9N8L0_POPTR Methylenetetrahydrofolate reductase OS=Populus
trichocarpa GN=MTHFR2 PE=3 SV=1
Length = 606
Score = 403 bits (1035), Expect = 1e-110
Identities = 182/230 (79%), Positives = 208/230 (90%)
Frame = +2
Query: 71 TDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTADLTLDIVSRM 250
+ K FSFEFFPP+T+DGVDNLFERMDR+V++ P+FCDITWGAGG+TADLTLDI ++M
Sbjct: 22 SSNNKVVFSFEFFPPKTDDGVDNLFERMDRMVSHNPSFCDITWGAGGSTADLTLDIANKM 81
Query: 251 QNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENKFVQVEGGFGC 430
QN++CVE+MMHLTCTNMPVEKIDHALETI+SNGIQNVLALRGDPPHG++KFVQ++GG C
Sbjct: 82 QNIICVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQIQGGLAC 141
Query: 431 ALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLKKKVDAGADLI 610
ALDLV HIRSKYGDYFG+ VAGYPEAHPDVIG +G A+ E Y DL YLK+KVDAGADLI
Sbjct: 142 ALDLVKHIRSKYGDYFGITVAGYPEAHPDVIGSDGFATLEDYHKDLAYLKQKVDAGADLI 201
Query: 611 VTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
VTQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGF+RM GFC+ +
Sbjct: 202 VTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPINNYKGFIRMAGFCKTK 251
>tr|A2XNC0|A2XNC0_ORYSI Methylenetetrahydrofolate reductase OS=Oryza sativa
subsp. indica GN=OsI_14054 PE=3 SV=1
Length = 594
Score = 403 bits (1034), Expect = 1e-110
Identities = 186/240 (77%), Positives = 214/240 (89%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKV++KI+ +G+T FSFE+FPP+TE+G+DNLFERMDR+VA+GP FCDITWGAGG+TA
Sbjct: 1 MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
DLTL+I +RMQN+VCVE+MMHLTCTNMPVEKID AL TI+SNGIQNVLALRGDPPHG++K
Sbjct: 61 DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FVQV GGF CALDLV HIR+KYGDYFG+ VAGYPEAHPD I A+ EAY +DL YLK
Sbjct: 121 FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
+KVDAGADLI+TQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGFLRM GFC+ +
Sbjct: 181 QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK 240
>tr|Q10BJ6|Q10BJ6_ORYSJ Methylenetetrahydrofolate reductase OS=Oryza sativa
subsp. japonica GN=LOC_Os03g60090 PE=3 SV=1
Length = 573
Score = 403 bits (1034), Expect = 1e-110
Identities = 186/240 (77%), Positives = 214/240 (89%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKV++KI+ +G+T FSFE+FPP+TE+G+DNLFERMDR+VA+GP FCDITWGAGG+TA
Sbjct: 1 MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
DLTL+I +RMQN+VCVE+MMHLTCTNMPVEKID AL TI+SNGIQNVLALRGDPPHG++K
Sbjct: 61 DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FVQV GGF CALDLV HIR+KYGDYFG+ VAGYPEAHPD I A+ EAY +DL YLK
Sbjct: 121 FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
+KVDAGADLI+TQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGFLRM GFC+ +
Sbjct: 181 QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK 240
>tr|Q10BJ7|Q10BJ7_ORYSJ Methylenetetrahydrofolate reductase OS=Oryza sativa
subsp. japonica GN=Os03g0815200 PE=3 SV=1
Length = 594
Score = 403 bits (1034), Expect = 1e-110
Identities = 186/240 (77%), Positives = 214/240 (89%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKV++KI+ +G+T FSFE+FPP+TE+G+DNLFERMDR+VA+GP FCDITWGAGG+TA
Sbjct: 1 MKVIEKIQEAAADGRTVFSFEYFPPKTEEGLDNLFERMDRMVAHGPNFCDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
DLTL+I +RMQN+VCVE+MMHLTCTNMPVEKID AL TI+SNGIQNVLALRGDPPHG++K
Sbjct: 61 DLTLEIANRMQNMVCVETMMHLTCTNMPVEKIDDALTTIKSNGIQNVLALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FVQV GGF CALDLV HIR+KYGDYFG+ VAGYPEAHPD I A+ EAY +DL YLK
Sbjct: 121 FVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
+KVDAGADLI+TQLF+DTDI LKFVNDCRQIGI CPIVPGIMPINNYKGFLRM GFC+ +
Sbjct: 181 QKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTK 240
>tr|A9RW65|A9RW65_PHYPA Methylenetetrahydrofolate reductase OS=Physcomitrella
patens subsp. patens GN=PHYPADRAFT_161370 PE=3 SV=1
Length = 594
Score = 381 bits (978), Expect = 5e-104
Identities = 170/240 (70%), Positives = 209/240 (87%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKV+DKI + G FSFEFFPP+TE+GV+NLF+RMDR+V + PAFCDITWGAGG+T+
Sbjct: 1 MKVIDKINNGLAGGNVVFSFEFFPPKTEEGVENLFDRMDRMVRHQPAFCDITWGAGGSTS 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
+TLDI ++MQN++CVE+MMHLTCTNM VE +D+AL+ ++SNGIQN+LALRGDPPHG++K
Sbjct: 61 AITLDIANKMQNMICVETMMHLTCTNMLVETLDNALDNVKSNGIQNILALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FV ++GGF CALDLV HI+ KYGDYFG+ VAGYPEAHPDVIGE+G+AS+EAY+ DL YLK
Sbjct: 121 FVTIDGGFSCALDLVRHIKDKYGDYFGITVAGYPEAHPDVIGEDGIASEEAYKKDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
+K DAG ++IVTQLF+DTDI LKFVNDCRQIGIK P+VPGIMPI NYKGFLRM C+ +
Sbjct: 181 EKCDAGGEVIVTQLFYDTDIFLKFVNDCRQIGIKAPVVPGIMPIQNYKGFLRMTSLCKTK 240
>tr|A9U4S7|A9U4S7_PHYPA Methylenetetrahydrofolate reductase OS=Physcomitrella
patens subsp. patens GN=PHYPADRAFT_228287 PE=3 SV=1
Length = 592
Score = 380 bits (975), Expect = 1e-103
Identities = 171/240 (71%), Positives = 210/240 (87%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MKV+DKI + G FSFEFFPP+TE+GV+NLF+RMDR+V + PAFCDITWGAGG+T+
Sbjct: 1 MKVIDKINNGLAGGNVVFSFEFFPPKTEEGVENLFDRMDRMVMHQPAFCDITWGAGGSTS 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
+TLDI ++MQN++CVE+MMHLTCTNM VE +D AL++++SNGIQN+LALRGDPPHG++K
Sbjct: 61 AVTLDIANKMQNMICVETMMHLTCTNMLVETLDGALDSVKSNGIQNILALRGDPPHGQDK 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
FV +EGGF CALDLV HIR+KYGDYFG+ VAGYPEAHP+VIGE+G+AS+EAY+ DL YLK
Sbjct: 121 FVTIEGGFSCALDLVRHIRAKYGDYFGITVAGYPEAHPEVIGEDGVASEEAYQKDLAYLK 180
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
+K DAG ++I+TQLF+DTDI LKFVNDCRQIGIK PIVPGIMPI NYKGFLRM C+ +
Sbjct: 181 EKCDAGGEVIITQLFYDTDIFLKFVNDCRQIGIKVPIVPGIMPIQNYKGFLRMTTLCKTK 240
>tr|A6XMY8|A6XMY8_TRIMO Methylenetetrahydrofolate reductase OS=Triticum
monococcum PE=2 SV=1
Length = 582
Score = 371 bits (950), Expect = 8e-101
Identities = 173/217 (79%), Positives = 199/217 (91%), Gaps = 2/217 (0%)
Frame = +2
Query: 113 PRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTADLTLDIVSRMQNVVCVESMMHLTC 292
PR +GV+NLFERMDR+VA+GP FCDITWGAGG+TAD+TLDI +RMQN+VCVE+MMHLTC
Sbjct: 13 PRRREGVENLFERMDRMVAHGPNFCDITWGAGGSTADVTLDIANRMQNMVCVETMMHLTC 72
Query: 293 TNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENKFVQVEGGFGCALDLVNHIRSKYGD 472
TNMPVEKID+AL+TI+SNGIQNVLALRGDPPHG++KFVQV GGF CALDLV HI++KYGD
Sbjct: 73 TNMPVEKIDNALDTIKSNGIQNVLALRGDPPHGQDKFVQVAGGFSCALDLVEHIKAKYGD 132
Query: 473 YFGVAVAGYPEAHPDVI-GENGLASKEAYESDLEYLKKKVDAGADLIVTQLFFDTDILLK 649
YFG+ VAGYPEAHP+VI GE G A++EAY DL YLK+KVDAGAD+IVTQLF+DTDI LK
Sbjct: 133 YFGITVAGYPEAHPEVILGEEG-ATEEAYRKDLAYLKRKVDAGADVIVTQLFYDTDIFLK 191
Query: 650 FVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
FVNDCRQIGI CPIVPGIMPINNYKGF+RM GFC+ +
Sbjct: 192 FVNDCRQIGITCPIVPGIMPINNYKGFVRMTGFCKTK 228
>tr|A8IAY6|A8IAY6_CHLRE Methylenetetrahydrofolate reductase OS=Chlamydomonas
reinhardtii GN=CHLREDRAFT_111330 PE=3 SV=1
Length = 594
Score = 315 bits (805), Expect = 5e-084
Identities = 146/240 (60%), Positives = 187/240 (77%), Gaps = 6/240 (2%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MK++ K++ +G+T FSFEFFPPRTE+GV+NLFER+DR+VAYGP FCDITWGAGG+TA
Sbjct: 1 MKLIHKVEEKMKKGETFFSFEFFPPRTEEGVENLFERLDRMVAYGPVFCDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
D+TLDI +RMQN++CVE+MMHLTCTNMP EK++ AL ++ G+QN+LALRGDPP
Sbjct: 61 DVTLDIATRMQNLICVETMMHLTCTNMPEEKLESALHEVKKMGVQNILALRGDPPK---- 116
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESDLEYLK 580
V+V G C V+ S++GDYFG+ VAGYPEAHPD I ++ K+ Y +D+ YLK
Sbjct: 117 -VRV-GACVCVTSAVHQDESQHGDYFGICVAGYPEAHPDGIVDDPEQMKKNYWADIAYLK 174
Query: 581 KKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIGFCRPR 760
+KVDAG D+IVTQLF+D D+ L+FV DCR +GI CPI+PGIMPI Y GF RM GFC+ +
Sbjct: 175 QKVDAGGDMIVTQLFYDVDVFLQFVKDCRSVGITCPILPGIMPIMTYGGFKRMTGFCKTK 234
>tr|B8BVS6|B8BVS6_THAPS Methylenetetrahydrofolate reductase OS=Thalassiosira
pseudonana GN=THAPSDRAFT_27273 PE=3 SV=1
Length = 383
Score = 247 bits (628), Expect = 2e-063
Identities = 123/245 (50%), Positives = 163/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 44 KVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDR-LVAYGPAFCDITWGAGGTTA 220
K++D ++ T+ S E+FPPRT+ GV NL RMDR LV + D+TWGAGG+TA
Sbjct: 12 KIIDLLQRDTEIAHV--SLEYFPPRTDQGVKNLHARMDRMLVNTNALYTDMTWGAGGSTA 69
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNM-----PVEKIDHALETIRSNGIQNVLALRGDPP 385
DL+L++ V S MHLTCTNM PV+ + AL+ GI+N++ALRGDPP
Sbjct: 70 DLSLELALHAHKTGHV-SNMHLTCTNMEKDGDPVKAVHDALQQAYDGGIRNIVALRGDPP 128
Query: 386 HGENKFVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLASKEAYESD 565
GE ++ EGGF CALDLV +IR +GD FG++VAGYPE HP+ I + E Y+ +
Sbjct: 129 EGEKEWTATEGGFSCALDLVKYIRKTFGDKFGISVAGYPEGHPNRISQLSEEEDEDYKKE 188
Query: 566 LEYLKKKVDAGADLIVTQLFFDTDILLKFVNDCRQIGIKCPIVPGIMPINNYKGFLRMIG 745
++YLK+KVDAG D I+TQ+FFD ++ FVNDCR GI CP+VPG+M IN Y GF +M
Sbjct: 189 MDYLKEKVDAGGDFIITQMFFDAEVFKTFVNDCRTWGITCPVVPGLMCINAYPGFKKMTK 248
Query: 746 FCRPR 760
FC+ R
Sbjct: 249 FCKTR 253
>tr|D2V2R1|D2V2R1_NAEGR Methylenetetrahydrofolate reductase OS=Naegleria gruberi
GN=NAEGRDRAFT_35291 PE=3 SV=1
Length = 594
Score = 193 bits (490), Expect = 2e-047
Identities = 87/180 (48%), Positives = 128/180 (71%), Gaps = 1/180 (0%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MK++DKI +E KT +SFE+FPP+T+ GV+NL++R+ R+ P F DITWGAGG+TA
Sbjct: 1 MKIIDKINQCIEENKTFYSFEYFPPKTDAGVENLYQRLQRMAKLAPMFIDITWGAGGSTA 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
T++I + QN++ VE+ +H+TCTNM VE++D A++T + GI N+LALRGDPP G
Sbjct: 61 GKTIEIGATAQNMIGVETQIHMTCTNMKVEELDKAIQTAKDMGISNILALRGDPPLGSED 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVIGENGLA-SKEAYESDLEYL 577
+ Q +GGF A DL++HIR +GDYFG++ AGY E HP+ + L KE Y++ +++
Sbjct: 121 WEQTDGGFKYARDLISHIRKTHGDYFGISCAGYSEGHPEGDYQKDLMYLKEKYDAGADFV 180
>tr|A9UZU5|A9UZU5_MONBE Methylenetetrahydrofolate reductase OS=Monosiga
brevicollis GN=32490 PE=3 SV=1
Length = 332
Score = 190 bits (481), Expect = 2e-046
Identities = 88/160 (55%), Positives = 116/160 (72%)
Frame = +2
Query: 44 KVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTAD 223
K+ D+++ + +G+ SFEFFPPRT+DGV +L R+ R P F D+TWGAGG+T+D
Sbjct: 5 KISDRLQELSAKGEKFVSFEFFPPRTDDGVTSLMSRIQRYNDQQPLFMDMTWGAGGSTSD 64
Query: 224 LTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENKF 403
LTLD+ +RM + MHLTCTNMP EKID AL+ R GI+N++ALRGDPP GE +
Sbjct: 65 LTLDLCTRMVKECGANANMHLTCTNMPSEKIDIALKGARDAGIRNIVALRGDPPAGEEAW 124
Query: 404 VQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVI 523
VEGG+ CALDLV HIR ++GD+F +AV+GYPE HP+ I
Sbjct: 125 EAVEGGYSCALDLVKHIRKEHGDFFSIAVSGYPEGHPNAI 164
>tr|B0CU22|B0CU22_LACBS Methylenetetrahydrofolate reductase OS=Laccaria bicolor
(strain S238N-H82) GN=LACBIDRAFT_182479 PE=3 SV=1
Length = 602
Score = 180 bits (456), Expect = 2e-043
Identities = 83/155 (53%), Positives = 112/155 (72%)
Frame = +2
Query: 41 MKVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTA 220
MK+ KI+ + K +SFE+FPPRT G+ NL +R++R+ A GP F DITW AGG T+
Sbjct: 1 MKITQKIQQSANNDKIWWSFEYFPPRTAQGLQNLLDRIERMRALGPEFIDITWNAGGRTS 60
Query: 221 DLTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENK 400
DLT ++V Q ++ +E+ MHLTCTNMP EK+D AL + +G +NVLALRGDPP G+++
Sbjct: 61 DLTSEMVKTCQGLIGMETCMHLTCTNMPKEKVDIALREAKQHGCRNVLALRGDPPSGKDE 120
Query: 401 FVQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPE 505
+ VEGGF +DLV HIR YGDYF +AVAG+P+
Sbjct: 121 WEAVEGGFVHGIDLVRHIRRDYGDYFDIAVAGFPQ 155
>tr|Q4P5K1|Q4P5K1_USTMA Methylenetetrahydrofolate reductase OS=Ustilago maydis
GN=UM04612.1 PE=3 SV=1
Length = 650
Score = 177 bits (447), Expect = 2e-042
Identities = 81/160 (50%), Positives = 112/160 (70%)
Frame = +2
Query: 44 KVVDKIKSWTDEGKTTFSFEFFPPRTEDGVDNLFERMDRLVAYGPAFCDITWGAGGTTAD 223
K+ +KI EG+ +SFE+FPPRT G+ NL++R++R+ GP F DITW AGG T+D
Sbjct: 18 KITNKIAKAEKEGRIWWSFEYFPPRTAQGLTNLYDRIERMADLGPEFVDITWNAGGRTSD 77
Query: 224 LTLDIVSRMQNVVCVESMMHLTCTNMPVEKIDHALETIRSNGIQNVLALRGDPPHGENKF 403
LT +V + + +E+ MHLTCTNMP EKID AL+ + G +N+LALRGDPP G++++
Sbjct: 78 LTASLVKTVHTYIGLETCMHLTCTNMPREKIDTALKEAKEFGCRNILALRGDPPAGQSEW 137
Query: 404 VQVEGGFGCALDLVNHIRSKYGDYFGVAVAGYPEAHPDVI 523
GF A +LV +IR +YGDYF +AVAG+PE HP+ I
Sbjct: 138 EPHAAGFTRAKELVEYIREQYGDYFAIAVAGFPEGHPEAI 177
Database: UniProt/TrEMBL
Posted date: Sat Aug 07 14:51:12 2010
Number of letters in database: 3,661,877,547
Number of sequences in database: 11,397,958
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,549,685,735,968
Number of Sequences: 11397958
Number of Extensions: 1549685735968
Number of Successful Extensions: 572066229
Number of sequences better than 0.0: 0
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