BLASTX 7.6.2
Query= UN19174 /QuerySize=1116
(1115 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5ZLN0|LRC40_CHICK Leucine-rich repeat-containing protein 40 ... 70 2e-011
sp|Q54XZ5|Y0138_DICDI Probable serine/threonine-protein kinase D... 68 1e-010
sp|Q6DHL5|LRC57_DANRE Leucine-rich repeat-containing protein 57 ... 67 3e-010
sp|Q80ZI6|LRSM1_MOUSE E3 ubiquitin-protein ligase LRSAM1 OS=Mus ... 65 8e-010
sp|Q8C0R9|YG015_MOUSE Leucine-rich repeat and death domain-conta... 63 3e-009
sp|Q4H4B6|SCRIB_DANRE Protein scribble homolog OS=Danio rerio GN... 63 4e-009
sp|Q14160|SCRIB_HUMAN Protein scribble homolog OS=Homo sapiens G... 62 7e-009
sp|Q80U72|SCRIB_MOUSE Protein scribble homolog OS=Mus musculus G... 62 7e-009
sp|O61967|LAP1_CAEEL Protein lap1 OS=Caenorhabditis elegans GN=l... 60 3e-008
sp|A8XWW4|SHOC2_CAEBR Leucine-rich repeat protein soc-2 OS=Caeno... 60 3e-008
sp|Q4R3P6|LRC40_MACFA Leucine-rich repeat-containing protein 40 ... 60 3e-008
sp|Q22875|SHOC2_CAEEL Leucine-rich repeat protein soc-2 OS=Caeno... 60 3e-008
sp|Q6GPJ5|LRC40_XENLA Leucine-rich repeat-containing protein 40 ... 58 1e-007
sp|A4IIK1|MFHA1_XENTR Malignant fibrous histiocytoma-amplified s... 58 1e-007
sp|Q9Y2L9|LRCH1_HUMAN Leucine-rich repeat and calponin homology ... 57 2e-007
sp|P62046|LRCH1_MOUSE Leucine-rich repeat and calponin homology ... 55 1e-006
sp|Q54AX5|LRRA_DICDI Leucine-rich repeat protein lrrA OS=Dictyos... 54 1e-006
sp|Q8K3P5|CNOT6_MOUSE CCR4-NOT transcription complex subunit 6 O... 53 3e-006
>sp|Q5ZLN0|LRC40_CHICK Leucine-rich repeat-containing protein 40 OS=Gallus
gallus GN=LRRC40 PE=2 SV=1
Length = 603
Score = 70 bits (171), Expect = 2e-011
Identities = 37/97 (38%), Positives = 60/97 (61%), Gaps = 2/97 (2%)
Frame = +3
Query: 357 SSIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKL 536
S++G++ +L LD N+L +P+ + L++L+ L L N +L LP FG L+SL++L
Sbjct: 122 SALGQLENLQKLDVSHNKLKSIPEELLQLSHLKGLLLQHN--ELSHLPDGFGQLVSLEEL 179
Query: 537 DLSNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEV 647
DLSNN + +P +F L +LV LN+ N L P ++
Sbjct: 180 DLSNNHLTDIPKSFALLINLVRLNLACNQLKDLPADI 216
>sp|Q54XZ5|Y0138_DICDI Probable serine/threonine-protein kinase DDB_G0278509
OS=Dictyostelium discoideum GN=DDB_G0278509 PE=3 SV=1
Length = 1248
Score = 68 bits (164), Expect = 1e-010
Identities = 41/89 (46%), Positives = 55/89 (61%), Gaps = 2/89 (2%)
Frame = +3
Query: 360 SIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLD 539
+I + SL L+A N + LPDS L+NL+ LNL++N +LK+LPS+ G L L L
Sbjct: 636 AINNLSSLIELNASNNVIELLPDSICYLSNLKKLNLNNN--NLKELPSNIGFLTKLVDLQ 693
Query: 540 LSNNQIHSLPDTFGTLESLVELNVDQNPL 626
L NNQI SLP +F S+ E+ D NPL
Sbjct: 694 LYNNQISSLPISFLKCRSIREIGTDGNPL 722
>sp|Q6DHL5|LRC57_DANRE Leucine-rich repeat-containing protein 57 OS=Danio rerio
GN=lrrc57 PE=2 SV=1
Length = 238
Score = 67 bits (161), Expect = 3e-010
Identities = 47/132 (35%), Positives = 68/132 (51%), Gaps = 11/132 (8%)
Frame = +3
Query: 363 IGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDL 542
IG + L N+L LP+ L LE L L+ N LK LPSS G L SL+ L L
Sbjct: 57 IGSFQHLKSFTISCNKLTSLPNDIGKLKKLETLILNGN--QLKQLPSSIGQLKSLRTLSL 114
Query: 543 SNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEVVKEGVEAVKLYMGKRRITMLEEEER 722
S NQ P GTL L L++ +N + V P EV + ++A+++ + + +I+ + +E
Sbjct: 115 SGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVPAEVAE--LQAIEINLNQNQISSVTQEVS 172
Query: 723 R-------RLEE 737
R RLEE
Sbjct: 173 RTPRLKVLRLEE 184
>sp|Q80ZI6|LRSM1_MOUSE E3 ubiquitin-protein ligase LRSAM1 OS=Mus musculus
GN=Lrsam1 PE=2 SV=1
Length = 727
Score = 65 bits (157), Expect = 8e-010
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 2/89 (2%)
Frame = +3
Query: 360 SIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLD 539
S+ + ++ LD H N+L LPD LT L+ LN+ N L LP S G+L+ LQ L+
Sbjct: 76 SLLSLVTIKVLDLHENQLTALPDDMGQLTVLQVLNVERN--QLTHLPRSIGNLLQLQTLN 133
Query: 540 LSNNQIHSLPDTFGTLESLVELNVDQNPL 626
+ +N++ LPDT G L SL L++ +N +
Sbjct: 134 VKDNKLKELPDTLGELRSLRTLDISENEI 162
>sp|Q8C0R9|YG015_MOUSE Leucine-rich repeat and death domain-containing protein
LOC401387 homolog OS=Mus musculus PE=2 SV=1
Length = 853
Score = 63 bits (152), Expect = 3e-009
Identities = 49/168 (29%), Positives = 77/168 (45%), Gaps = 11/168 (6%)
Frame = +3
Query: 363 IGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDL 542
+ M L L+ N + +P + L +L S+N + LPSSF L LQ LDL
Sbjct: 641 VSHMTQLKILNISNNAIKDIPKNIGELRSLVSFYASNN--QISSLPSSFLSLEVLQSLDL 698
Query: 543 SNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEVVK-EGVEAVKLYMGKRRITMLEEEE 719
N + +LP L SL E+N D NPL+ PP+E+ K + + + Y+ + +E
Sbjct: 699 RGNNMTALPSGIYKLSSLKEINFDDNPLMRPPMEICKGKEMHMITCYLQR------ADER 752
Query: 720 RRRLEEEMEQANAGWITRTTSKLKSYVSDVSEYLN--PTSPRDPYLER 857
++ E++ A IT T + +++ N P P P ER
Sbjct: 753 DEKILEKIFNIVANSITETNFEFLQQKLNMASSANNMPVRPTTPLNER 800
>sp|Q4H4B6|SCRIB_DANRE Protein scribble homolog OS=Danio rerio GN=scrib PE=1
SV=1
Length = 1724
Score = 63 bits (151), Expect = 4e-009
Identities = 38/93 (40%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
Frame = +3
Query: 369 EMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSN 548
++R L++L + L LP+ L+NL L L N LK LPSS L+ L++LDL +
Sbjct: 126 QLRGLAHLSLNDVSLQSLPNDIGNLSNLVTLELRENL--LKSLPSSLSFLVKLEQLDLGS 183
Query: 549 NQIHSLPDTFGTLESLVELNVDQNPLVVPPLEV 647
N + LPDT G L +L EL +D+N L P E+
Sbjct: 184 NVLEVLPDTLGALPNLRELWLDRNQLSSLPPEL 216
>sp|Q14160|SCRIB_HUMAN Protein scribble homolog OS=Homo sapiens GN=SCRIB PE=1
SV=4
Length = 1630
Score = 62 bits (149), Expect = 7e-009
Identities = 38/93 (40%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Frame = +3
Query: 369 EMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSN 548
++RSL++L + L LP L NL L L N LK LP+S L+ L++LDL
Sbjct: 126 QLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENL--LKSLPASLSFLVKLEQLDLGG 183
Query: 549 NQIHSLPDTFGTLESLVELNVDQNPLVVPPLEV 647
N + LPDT G L +L EL +D+N L P E+
Sbjct: 184 NDLEVLPDTLGALPNLRELWLDRNQLSALPPEL 216
>sp|Q80U72|SCRIB_MOUSE Protein scribble homolog OS=Mus musculus GN=Scrib PE=1
SV=2
Length = 1612
Score = 62 bits (149), Expect = 7e-009
Identities = 38/93 (40%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Frame = +3
Query: 369 EMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSN 548
++RSL++L + L LP L NL L L N LK LP+S L+ L++LDL
Sbjct: 126 QLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENL--LKSLPASLSFLVKLEQLDLGG 183
Query: 549 NQIHSLPDTFGTLESLVELNVDQNPLVVPPLEV 647
N + LPDT G L +L EL +D+N L P E+
Sbjct: 184 NDLEVLPDTLGALPNLRELWLDRNQLSALPPEL 216
>sp|O61967|LAP1_CAEEL Protein lap1 OS=Caenorhabditis elegans GN=let-413 PE=1
SV=3
Length = 699
Score = 60 bits (144), Expect = 3e-008
Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +3
Query: 360 SIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLD 539
SI R L LD N++ LP++ + NL LN+S N ++ +LPSSFG+L LQ L
Sbjct: 215 SISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISIN--EIIELPSSFGELKRLQMLK 272
Query: 540 LSNNQIHSLPDTFGTLESLVELNVDQNPLVVPP 638
N +H+L G +SL EL + QN L P
Sbjct: 273 ADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLP 305
>sp|A8XWW4|SHOC2_CAEBR Leucine-rich repeat protein soc-2 OS=Caenorhabditis
briggsae GN=soc-2 PE=3 SV=1
Length = 559
Score = 60 bits (144), Expect = 3e-008
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 8/154 (5%)
Frame = +3
Query: 381 LSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSNNQIH 560
L+ L+ NEL LP T++ LNLS+N LK LP L++L+ L LSNNQ+
Sbjct: 354 LTKLNLKENELVSLPLDMGSWTSITELNLSTN--QLKVLPEDIEKLVNLEILVLSNNQLK 411
Query: 561 SLPDTFGTLESLVELNVDQNPLVVPPLEV------VKEGVEAVKLYMGKRRITMLEEEER 722
LP+ G L+ L EL++++N L P E+ K V++ K+ R I L +
Sbjct: 412 KLPNQIGNLKKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKIVTLPRSIGNLCSLQD 471
Query: 723 RRLEEEMEQANAGWITRTTSKLKSYVSDVSEYLN 824
RL E A I S Y++D S N
Sbjct: 472 LRLGENNLTAIPEEIGHLDSLKSLYLNDNSSLHN 505
Score = 54 bits (129), Expect = 1e-006
Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Frame = +3
Query: 390 LDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSNNQIHSLP 569
LD E+ +P LT L L L N L LP+ G L++L+KL LS N + SLP
Sbjct: 78 LDLSSIEITSIPSPIKELTQLTELFLYKN--KLTCLPTEIGQLVNLKKLGLSENALSSLP 135
Query: 570 DTFGTLESLVELNVDQNPLVVPPLEVVKEGVEAVKLYMGKRRITMLEEE 716
D+ +LESL L++ N L P V+ + L++ RI ++E+
Sbjct: 136 DSLSSLESLETLDLRHNKLTEVP-AVIYKITSLETLWLRYNRIVAVDEQ 183
>sp|Q4R3P6|LRC40_MACFA Leucine-rich repeat-containing protein 40 OS=Macaca
fascicularis GN=LRRC40 PE=2 SV=1
Length = 602
Score = 60 bits (143), Expect = 3e-008
Identities = 35/97 (36%), Positives = 55/97 (56%), Gaps = 2/97 (2%)
Frame = +3
Query: 357 SSIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKL 536
S++ E+ +L L+ N+L P+ L NL+ L L N +L + F L +L+ L
Sbjct: 122 SAMRELENLQKLNVSHNKLKIFPEEITNLRNLKCLYLQHN--ELTCISEGFEQLSNLEDL 179
Query: 537 DLSNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEV 647
DLSNN++ ++P +F +L SLV LN+ N L P E+
Sbjct: 180 DLSNNRLTTVPASFSSLSSLVRLNLSSNQLKSLPAEI 216
>sp|Q22875|SHOC2_CAEEL Leucine-rich repeat protein soc-2 OS=Caenorhabditis
elegans GN=soc-2 PE=1 SV=3
Length = 559
Score = 60 bits (143), Expect = 3e-008
Identities = 52/154 (33%), Positives = 73/154 (47%), Gaps = 8/154 (5%)
Frame = +3
Query: 381 LSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSNNQIH 560
L+ L+ NEL LP T++ LNLS+N LK LP L++L+ L LSNNQ+
Sbjct: 354 LTKLNLKENELVSLPLDMGSWTSITELNLSTN--QLKVLPEDIEKLVNLEILVLSNNQLK 411
Query: 561 SLPDTFGTLESLVELNVDQNPLVVPPLEV------VKEGVEAVKLYMGKRRITMLEEEER 722
LP+ G L L EL++++N L P E+ K V++ K+ R I L +
Sbjct: 412 KLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQD 471
Query: 723 RRLEEEMEQANAGWITRTTSKLKSYVSDVSEYLN 824
RL E A I S Y++D S N
Sbjct: 472 LRLGENNLTAIPEEIGHLDSLKSLYLNDNSSLHN 505
Score = 56 bits (133), Expect = 5e-007
Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Frame = +3
Query: 390 LDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSNNQIHSLP 569
LD E+ +P LT L L L N L LP+ G L++L+KL LS N + SLP
Sbjct: 78 LDLSSIEITSIPSPIKELTQLTELFLYKN--KLTCLPTEIGQLVNLKKLGLSENALTSLP 135
Query: 570 DTFGTLESLVELNVDQNPLVVPPLEVVKEGVEAVKLYMGKRRITMLEEE 716
D+ +LESL L++ N L P + K G L++ RI ++E+
Sbjct: 136 DSLASLESLETLDLRHNKLTEVPSVIYKIG-SLETLWLRYNRIVAVDEQ 183
>sp|Q6GPJ5|LRC40_XENLA Leucine-rich repeat-containing protein 40 OS=Xenopus
laevis GN=lrrc40 PE=2 SV=1
Length = 605
Score = 58 bits (138), Expect = 1e-007
Identities = 38/108 (35%), Positives = 58/108 (53%), Gaps = 3/108 (2%)
Frame = +3
Query: 372 MRSLSYLDAHFNELHGL-PDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSN 548
+ L L N++ L P+ L++L L L ++ LK LP L L++LDLSN
Sbjct: 264 LTKLKELHVGNNQIQTLGPEHLQNLSSLSVLEL--RYNKLKVLPKEISLLKGLERLDLSN 321
Query: 549 NQIHSLPDTFGTLESLVELNVDQNPLVVPPLEVVKEGVEAVKLYMGKR 692
N I SLPDT G+L +L L +D NPL +++ +G + + Y+ R
Sbjct: 322 NDIGSLPDTLGSLPNLKSLQLDGNPLRGIRRDILNKGTQELLKYLKGR 369
>sp|A4IIK1|MFHA1_XENTR Malignant fibrous histiocytoma-amplified sequence 1
homolog OS=Xenopus tropicalis GN=mfhas1 PE=2 SV=1
Length = 997
Score = 58 bits (138), Expect = 1e-007
Identities = 44/141 (31%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +3
Query: 357 SSIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKL 536
+++ + L+ LD +N L L ++ LL L+ L LS N L+ LP G L+ L++L
Sbjct: 95 TAVYHLGRLTELDISYNRLSCLTEAVGLLGKLKKLCLSHN--QLRTLPRQLGMLVDLEEL 152
Query: 537 DLSNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEVVKEGVEAVKLYMGKRRITMLEEE 716
D+S NQI LPDT L SL L++D N L P ++ + G + + L E
Sbjct: 153 DVSFNQITHLPDTMQGLPSLRTLDLDHNELCSFPQQLFHVPALEELDFSGNKMLGSLPEG 212
Query: 717 ERRRLEEEMEQANAGWITRTT 779
R M+ W++ T+
Sbjct: 213 IR-----SMQSLKILWLSSTS 228
>sp|Q9Y2L9|LRCH1_HUMAN Leucine-rich repeat and calponin homology
domain-containing protein 1 OS=Homo sapiens GN=LRCH1 PE=1 SV=3
Length = 728
Score = 57 bits (136), Expect = 2e-007
Identities = 38/97 (39%), Positives = 54/97 (55%), Gaps = 3/97 (3%)
Frame = +3
Query: 360 SIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLD 539
+I ++ L+YL+ N+L LP L L L ++ + L LP G L L +LD
Sbjct: 138 AIVNLQMLTYLNLSRNQLSALP---ACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELD 194
Query: 540 LSNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEVV 650
+S N+I +LP G L+SL ELNV +N L V P E+V
Sbjct: 195 VSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
>sp|P62046|LRCH1_MOUSE Leucine-rich repeat and calponin homology
domain-containing protein 1 OS=Mus musculus GN=Lrch1 PE=1 SV=1
Length = 709
Score = 55 bits (130), Expect = 1e-006
Identities = 37/97 (38%), Positives = 54/97 (55%), Gaps = 3/97 (3%)
Frame = +3
Query: 360 SIGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLD 539
+I ++ L++L+ N+L LP L L L ++ + L LP G L L +LD
Sbjct: 128 AIVNLQMLTHLNLSRNQLSALP---ACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELD 184
Query: 540 LSNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEVV 650
+S N+I +LP G L+SL ELNV +N L V P E+V
Sbjct: 185 VSCNEITALPQQIGQLKSLRELNVRRNYLKVLPPELV 221
>sp|Q54AX5|LRRA_DICDI Leucine-rich repeat protein lrrA OS=Dictyostelium
discoideum GN=lrrA PE=1 SV=1
Length = 510
Score = 54 bits (129), Expect = 1e-006
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +3
Query: 363 IGEMRSLSYLDAHFNELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDL 542
I + +L LD N + +P L NL+ L+L N + ++PS G L++L+KL L
Sbjct: 289 IATLINLQKLDLFGNNMRIVPREVGNLINLQTLDLRQNKLTIDNIPSEIGKLVNLKKLLL 348
Query: 543 SNNQIHSLPDTFGTLESLVELNVDQNPLVVPPLEV 647
SNN + +LP ++++L E N L P E+
Sbjct: 349 SNNLLIALPPEIASMKALKEFEASNNQLQAIPTEI 383
>sp|Q8K3P5|CNOT6_MOUSE CCR4-NOT transcription complex subunit 6 OS=Mus musculus
GN=Cnot6 PE=1 SV=2
Length = 557
Score = 53 bits (126), Expect = 3e-006
Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 ELHGLPDSFVLLTNLEYLNLSSNFSDLKDLPSSFGDLISLQKLDLSNNQIHSLPDTFGTL 587
++ L S LT+L L+LS N L +PS L +L LDLS+NQI SLP G +
Sbjct: 39 KVRSLSSSLWSLTHLTALHLSDN--SLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNM 96
Query: 588 ESLVELNVDQNPLVVPPLEVVK 653
SL EL+++ N L V P E+ K
Sbjct: 97 VSLRELHLNYNQLRVLPFELGK 118
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,378,909,851
Number of Sequences: 518415
Number of Extensions: 78378909851
Number of Successful Extensions: 523441567
Number of sequences better than 0.0: 0
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