BLASTX 7.6.2
Query= UN19363 /QuerySize=1122
(1121 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P34066|PSA1A_ARATH Proteasome subunit alpha type-1-A OS=Arabi... 517 1e-145
sp|O23712|PSA1B_ARATH Proteasome subunit alpha type-1-B OS=Arabi... 507 1e-142
sp|P52428|PSA1_ORYSJ Proteasome subunit alpha type-1 OS=Oryza sa... 378 5e-104
sp|Q27562|PSA1_DICDI Proteasome subunit alpha type-1 OS=Dictyost... 266 3e-070
sp|Q9R1P4|PSA1_MOUSE Proteasome subunit alpha type-1 OS=Mus musc... 259 4e-068
sp|P18420|PSA1_RAT Proteasome subunit alpha type-1 OS=Rattus nor... 257 1e-067
sp|P25786|PSA1_HUMAN Proteasome subunit alpha type-1 OS=Homo sap... 256 2e-067
sp|Q5REN2|PSA1_PONAB Proteasome subunit alpha type-1 OS=Pongo ab... 255 4e-067
sp|Q3T0X5|PSA1_BOVIN Proteasome subunit alpha type-1 OS=Bos taur... 255 7e-067
sp|Q4R3H2|PSA1_MACFA Proteasome subunit alpha type-1 OS=Macaca f... 255 7e-067
sp|O14250|PSA1_SCHPO Probable proteasome subunit alpha type-1 OS... 243 3e-063
sp|P12881|PSA1_DROME Proteasome subunit alpha type-1 OS=Drosophi... 241 8e-063
sp|O42265|PSA1_CHICK Proteasome subunit alpha type-1 OS=Gallus g... 240 2e-062
sp|P92188|PSA1_TRYCR Proteasome subunit alpha type-1 OS=Trypanos... 236 3e-061
sp|O96788|PSA1_TRYBR Proteasome subunit alpha type-1 OS=Trypanos... 225 8e-058
sp|O44156|PSA1_CAEEL Proteasome subunit alpha type-1 OS=Caenorha... 221 9e-057
sp|P40302|PSA1_YEAST Proteasome component PRE5 OS=Saccharomyces ... 215 6e-055
sp|C3N5R0|PSMA_SULIA Proteasome subunit alpha OS=Sulfolobus isla... 153 3e-036
sp|C4KHD9|PSMA_SULIK Proteasome subunit alpha OS=Sulfolobus isla... 153 3e-036
sp|C3MQ43|PSMA_SULIL Proteasome subunit alpha OS=Sulfolobus isla... 153 3e-036
>sp|P34066|PSA1A_ARATH Proteasome subunit alpha type-1-A OS=Arabidopsis thaliana
GN=PAF1 PE=1 SV=3
Length = 278
Score = 517 bits (1329), Expect = 1e-145
Identities = 264/280 (94%), Positives = 270/280 (96%), Gaps = 7/280 (2%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ
Sbjct: 1 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
+KIFKVDDHIGVAIAGLTADGRVLSRYMRSE+INHSFTYESPLPVGRLVVHLADKAQVCT
Sbjct: 61 RKIFKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG
Sbjct: 121 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 180
Query: 632 DSSKEDLIKDAILAVRETLQGETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVPE 811
DSS+EDLIKDAILAVRETLQGETLKSSLCTV++LGV EPFHFLDQE IQKVIDTFEKVPE
Sbjct: 181 DSSREDLIKDAILAVRETLQGETLKSSLCTVAILGVDEPFHFLDQEAIQKVIDTFEKVPE 240
Query: 812 EE--EGEAGEGE---AEAAPAEQGGDGGGAGDQDVAPMEM 916
EE EGEAGEGE AEAAPAE+G GG AGDQDVAPMEM
Sbjct: 241 EEEGEGEAGEGEAEAAEAAPAERG--GGVAGDQDVAPMEM 278
>sp|O23712|PSA1B_ARATH Proteasome subunit alpha type-1-B OS=Arabidopsis thaliana
GN=PAF2 PE=1 SV=2
Length = 277
Score = 507 bits (1303), Expect = 1e-142
Identities = 257/278 (92%), Positives = 268/278 (96%), Gaps = 4/278 (1%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ
Sbjct: 1 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
+KIFKVDDHIGVAIAGLTADGRVLSRYMRSE+INHSFTYESPLPVGRLVVHLADKAQVCT
Sbjct: 61 RKIFKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLER+FESF
Sbjct: 121 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERKFESFQ 180
Query: 632 DSSKEDLIKDAILAVRETLQGETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVPE 811
+SSKEDLIKDAI+A+RETLQGETLKSSLCTVSVLGV EPFHFLDQE+IQKVIDTFEKVPE
Sbjct: 181 ESSKEDLIKDAIMAIRETLQGETLKSSLCTVSVLGVDEPFHFLDQESIQKVIDTFEKVPE 240
Query: 812 EEEGEAGEGEA--EAAPAEQG-GDGGGAGDQDVAPMEM 916
EEE +AGEGEA EAAP G G+ GG+GDQDVAPME+
Sbjct: 241 EEE-DAGEGEAEPEAAPGAAGTGEQGGSGDQDVAPMEI 277
>sp|P52428|PSA1_ORYSJ Proteasome subunit alpha type-1 OS=Oryza sativa subsp.
japonica GN=PAF1 PE=2 SV=1
Length = 270
Score = 378 bits (969), Expect = 5e-104
Identities = 188/275 (68%), Positives = 219/275 (79%), Gaps = 10/275 (3%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYDTDVTTWSP GRLFQVEYAMEAVKQGSA +GLRSR+H VLA NKA SELSSHQ
Sbjct: 1 MFRNQYDTDVTTWSPAGRLFQVEYAMEAVKQGSACVGLRSRTHAVLAAANKAASELSSHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
+K+F+V DH GVA+AGLTADGRVLSR++RSE INH+F Y++PLPV RL + LADKAQVCT
Sbjct: 61 RKVFRVADHAGVALAGLTADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QRSWKRPYGVGLLV GLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKT+LERRFE +
Sbjct: 121 QRSWKRPYGVGLLVAGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYN 180
Query: 632 DSSKEDLIKDAILAVRETLQGETLKSSLCTVSVL-----GVGEPFHFLDQETIQKVIDTF 796
D + E LIKDA+ A++ETLQGE L SS CTV+++ G EPF +D + IQ++ID+
Sbjct: 181 DYTPEQLIKDALSAIKETLQGEKLTSSNCTVAIVGRKDDGTVEPFEMIDVKRIQEIIDSM 240
Query: 797 EKVPEEEEGEAGEGEAEAAPAEQGGDGGGAGDQDV 901
E EA EAE++ ++ G A D+
Sbjct: 241 EAAE-----EAPAAEAESSSMQEEDKGTDAAPMDI 270
>sp|Q27562|PSA1_DICDI Proteasome subunit alpha type-1 OS=Dictyostelium
discoideum GN=psmA1 PE=3 SV=1
Length = 248
Score = 266 bits (678), Expect = 3e-070
Identities = 126/238 (52%), Positives = 177/238 (74%), Gaps = 2/238 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
M+RNQYD+D+TT+SP+GR+ Q+EYAMEAVKQG AA+ L+S+ VL + ++ SEL S+Q
Sbjct: 1 MYRNQYDSDITTFSPSGRIHQIEYAMEAVKQGGAAVALKSKQFAVLVSLKRSSSELGSYQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKIF VDDH+G+AI+GLTAD R+L YMR+E N+++ YES + V RLV +ADK QV T
Sbjct: 61 KKIFVVDDHVGIAISGLTADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLLV G D+ GAH+Y CPSGN+++Y++ +IGSRSQ+AKTYLE+ FESF
Sbjct: 121 QRYGRRPYGVGLLVAGYDQLGAHIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFE 180
Query: 632 DSSKEDLIKDAILAVRETLQG--ETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFE 799
+ + E LI + A+RET+ +TL S ++ ++G G+PF +++ Q ++ E
Sbjct: 181 ECTLEQLITHGLRALRETIPNTDDTLNSKNVSIGIVGEGQPFKIIEEADAQPYLNLLE 238
>sp|Q9R1P4|PSA1_MOUSE Proteasome subunit alpha type-1 OS=Mus musculus GN=Psma1
PE=1 SV=1
Length = 263
Score = 259 bits (660), Expect = 4e-068
Identities = 125/262 (47%), Positives = 178/262 (67%), Gaps = 4/262 (1%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD DVT WSP GR+ Q+EYAMEAVKQGSA +GL+S++H VL + +AQSEL++HQ
Sbjct: 1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKI VD+HIG++IAGLTAD R+L +MR E ++ F ++ PLPV RLV + K Q+ T
Sbjct: 61 KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLL+ G D+ G H++ CPS NYF+ +A +IG+RSQ+A+TYLER F
Sbjct: 121 QRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
Query: 632 DSSKEDLIKDAILAVRETLQGE-TLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVP 808
+ + ++L+K + A+RETL E L + ++ ++G F D + + +D E+ P
Sbjct: 181 ECNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEERP 240
Query: 809 EEEEGEAGEGEAEAAPAEQGGD 874
+ +A +A PAE+ +
Sbjct: 241 QR---KAQPSQAAEEPAEKADE 259
>sp|P18420|PSA1_RAT Proteasome subunit alpha type-1 OS=Rattus norvegicus
GN=Psma1 PE=1 SV=2
Length = 263
Score = 257 bits (656), Expect = 1e-067
Identities = 125/262 (47%), Positives = 177/262 (67%), Gaps = 4/262 (1%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD DVT WSP GR+ Q+EYAMEAVKQGSA +GL+S++H VL + +AQSEL++HQ
Sbjct: 1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKI VD+HIG++IAGLTAD R+L +MR E ++ F ++ PLPV RLV + K Q+ T
Sbjct: 61 KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLL+ G D+ G H++ CPS NYF+ +A +IG+RSQ+A+TYLER F
Sbjct: 121 QRYGRRPYGVGLLIAGYDDMGPHVFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
Query: 632 DSSKEDLIKDAILAVRETLQGE-TLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVP 808
+ ++L+K + A+RETL E L + ++ ++G F D + + +D E+ P
Sbjct: 181 QCNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEERP 240
Query: 809 EEEEGEAGEGEAEAAPAEQGGD 874
+ +A +A PAE+ +
Sbjct: 241 QR---KAQPSQAADEPAEKADE 259
>sp|P25786|PSA1_HUMAN Proteasome subunit alpha type-1 OS=Homo sapiens GN=PSMA1
PE=1 SV=1
Length = 263
Score = 256 bits (653), Expect = 2e-067
Identities = 122/259 (47%), Positives = 175/259 (67%), Gaps = 1/259 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD DVT WSP GR+ Q+EYAMEAVKQGSA +GL+S++H VL + +AQSEL++HQ
Sbjct: 1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKI VD+HIG++IAGLTAD R+L +MR E ++ F ++ PLPV RLV + K Q+ T
Sbjct: 61 KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLL+ G D+ G H++ CPS NYF+ +A +IG+RSQ+A+TYLER F
Sbjct: 121 QRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
Query: 632 DSSKEDLIKDAILAVRETLQGE-TLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVP 808
+ + +L+K + A+RETL E L + ++ ++G F D + + ++ E+ P
Sbjct: 181 ECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERP 240
Query: 809 EEEEGEAGEGEAEAAPAEQ 865
+ + A + A A++
Sbjct: 241 QRKAQPAQPADEPAEKADE 259
>sp|Q5REN2|PSA1_PONAB Proteasome subunit alpha type-1 OS=Pongo abelii GN=PSMA1
PE=2 SV=1
Length = 263
Score = 255 bits (651), Expect = 4e-067
Identities = 122/259 (47%), Positives = 175/259 (67%), Gaps = 1/259 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD DVT WSP GR+ Q+EYAMEAVKQGSA +GL+S++H VL + +AQSEL++HQ
Sbjct: 1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKI VD+HIG++IAGLTAD R+L +MR E ++ F ++ PLPV RLV + K Q+ T
Sbjct: 61 KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLL+ G D+ G H++ CPS NYF+ +A +IG+RSQ+A+TYLER F
Sbjct: 121 QRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
Query: 632 DSSKEDLIKDAILAVRETLQGE-TLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVP 808
+ + +L+K + A+RETL E L + ++ ++G F D + + ++ E+ P
Sbjct: 181 ECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIHDDDDVSPFLEGLEERP 240
Query: 809 EEEEGEAGEGEAEAAPAEQ 865
+ + A + A A++
Sbjct: 241 QRKAQPAQPADEPAEKADE 259
>sp|Q3T0X5|PSA1_BOVIN Proteasome subunit alpha type-1 OS=Bos taurus GN=PSMA1
PE=1 SV=1
Length = 263
Score = 255 bits (649), Expect = 7e-067
Identities = 121/259 (46%), Positives = 174/259 (67%), Gaps = 1/259 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD DVT WSP GR+ Q+EYAMEAVKQGSA +GL+S++H VL + +AQSEL++HQ
Sbjct: 1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKI VD+HIG++IAGLTAD R+L +MR E ++ F ++ PLPV RLV + K Q+ T
Sbjct: 61 KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLL+ G D+ G H++ CPS NYF+ +A +IG+RSQ+A+TYLER F
Sbjct: 121 QRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
Query: 632 DSSKEDLIKDAILAVRETLQGE-TLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVP 808
+ + +L+K + A+RETL E L + ++ ++G F D + + ++ E+ P
Sbjct: 181 ECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERP 240
Query: 809 EEEEGEAGEGEAEAAPAEQ 865
+ + + A A++
Sbjct: 241 QRKAQPTQPADEPAEKADE 259
>sp|Q4R3H2|PSA1_MACFA Proteasome subunit alpha type-1 OS=Macaca fascicularis
GN=PSMA1 PE=2 SV=1
Length = 263
Score = 255 bits (649), Expect = 7e-067
Identities = 121/259 (46%), Positives = 175/259 (67%), Gaps = 1/259 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD DVT WSP GR+ Q+EYAMEAVKQGSA +GL+S++H VL + +AQSEL++H+
Sbjct: 1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHR 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKI VD+HIG++IAGLTAD R+L +MR E ++ F ++ PLPV RLV + K Q+ T
Sbjct: 61 KKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLL+ G D+ G H++ CPS NYF+ +A +IG+RSQ+A+TYLER F
Sbjct: 121 QRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
Query: 632 DSSKEDLIKDAILAVRETLQGE-TLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVP 808
+ + +L+K + A+RETL E L + ++ ++G F D + + ++ E+ P
Sbjct: 181 ECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERP 240
Query: 809 EEEEGEAGEGEAEAAPAEQ 865
+ + A + A A++
Sbjct: 241 QRKAQPAQPADEPAEKADE 259
>sp|O14250|PSA1_SCHPO Probable proteasome subunit alpha type-1
OS=Schizosaccharomyces pombe GN=SPAC6G10.04c PE=2 SV=1
Length = 272
Score = 243 bits (618), Expect = 3e-063
Identities = 126/260 (48%), Positives = 171/260 (65%), Gaps = 2/260 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD D TTWSP GRL QVEYA+EA+KQGSA +GL S++H VL + + ELSS+Q
Sbjct: 1 MFRNQYDGDATTWSPQGRLHQVEYALEAIKQGSATVGLVSKTHAVLVALKRNAEELSSYQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KK+ ++DDHIG+AIAGL D RVLS YM+ EA++ + P+PV RL+ +A+KAQ+ T
Sbjct: 61 KKLIRIDDHIGIAIAGLAPDARVLSNYMKQEALSSKTLFTRPIPVRRLMSKVAEKAQINT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
Q +RPYGVG LV G DESG HL PSG EY ++GSRSQ+A+TY+ER ++F
Sbjct: 121 QEYGRRPYGVGFLVIGYDESGPHLLEFQPSGLVLEYLGTSMGSRSQSARTYIERNLDTFP 180
Query: 632 DSSKEDLIKDAILAVRETL-QGETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTF-EKV 805
DSS+E+LI A+ A+R+TL + + L ++SV+G E + DQ ++ +D +K
Sbjct: 181 DSSREELILSALRALRDTLSKDQELTEENVSISVIGKDEKYTLYDQNDTKEWLDKLGDKG 240
Query: 806 PEEEEGEAGEGEAEAAPAEQ 865
P E AP +
Sbjct: 241 PAAARASRAAAEEPQAPTAE 260
>sp|P12881|PSA1_DROME Proteasome subunit alpha type-1 OS=Drosophila melanogaster
GN=Pros35 PE=1 SV=1
Length = 279
Score = 241 bits (614), Expect = 8e-063
Identities = 125/266 (46%), Positives = 173/266 (65%), Gaps = 5/266 (1%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD+DVT WSP GRL QVEYAMEAVK G+A +GL+++ + VL + K SELS Q
Sbjct: 1 MFRNQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSDTQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
+KI +DDH+G++IAGLTAD RVLSRY+RSE +N+ +Y++ PV RL+ +L +K Q T
Sbjct: 61 RKIIPIDDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
QR +RPYGVGLLV G DE G H+Y PS +F +A +IGSRSQ+A+TYLE+ F
Sbjct: 121 QRYDRRPYGVGLLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFL 180
Query: 632 DSSKEDLIKDAILAVRETL----QGETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFE 799
DSSK+++I+ I A+ TL QG+ TV+++G +PF L + K +
Sbjct: 181 DSSKDEIIRHGIRAILGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHV-AIA 239
Query: 800 KVPEEEEGEAGEGEAEAAPAEQGGDG 877
K + + + + +P E+ G
Sbjct: 240 KENDNDTPRNDDDDDRPSPPEEPAAG 265
>sp|O42265|PSA1_CHICK Proteasome subunit alpha type-1 OS=Gallus gallus GN=PSMA1
PE=2 SV=2
Length = 260
Score = 240 bits (611), Expect = 2e-062
Identities = 115/248 (46%), Positives = 166/248 (66%), Gaps = 1/248 (0%)
Frame = +2
Query: 113 TDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQKKIFKVD 292
+DVT WSP GR+ Q+EYAMEAVKQGSA +GL+S++H VL + +AQSEL++HQKKI VD
Sbjct: 7 SDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILYVD 66
Query: 293 DHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCTQRSWKRP 472
+HIG++IAGLTAD R+L +MR E ++ F ++ PLPV RLV + K Q+ TQR +RP
Sbjct: 67 NHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRP 126
Query: 473 YGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSSKEDL 652
YGVGLL+ G D+ G H++ CPS NYF+ +A +IG+RSQ+A+ YLER F D + +L
Sbjct: 127 YGVGLLIAGYDDMGPHIFQTCPSANYFDCKAMSIGARSQSARNYLERHMTEFTDCNLNEL 186
Query: 653 IKDAILAVRETLQGE-TLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVPEEEEGEA 829
+K + A+RETL E L + ++ ++G F D + + ++ E+ P+ +
Sbjct: 187 VKHGLRALRETLPAEQDLTTKNVSIGIVGKDMEFTIYDDDDVAPFLEGLEERPQRKPALP 246
Query: 830 GEGEAEAA 853
+ AE A
Sbjct: 247 ADEPAEKA 254
>sp|P92188|PSA1_TRYCR Proteasome subunit alpha type-1 OS=Trypanosoma cruzi PE=2
SV=1
Length = 265
Score = 236 bits (600), Expect = 3e-061
Identities = 122/263 (46%), Positives = 179/263 (68%), Gaps = 3/263 (1%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQ-SELSSH 268
MF+NQYDT+ TTWSPTGRLFQVEYA EAV GSAA+G +++ VVL + ++ ++ SS+
Sbjct: 1 MFKNQYDTNTTTWSPTGRLFQVEYANEAVNNGSAAVGAKNKDFVVLTALKRSPVAQFSSY 60
Query: 269 QKKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVC 448
Q+K+FK+DDH+G+AIAGL ADGR+L+R++R+E +N+ + ++S P+ + + +K Q
Sbjct: 61 QEKVFKLDDHVGMAIAGLVADGRMLARFVRTECMNYRYMHDSDNPLPLIAEIVGEKYQRH 120
Query: 449 TQRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESF 628
Q + KRP+GVGLL+ G D +G HLY+ PSG+ F+++A A+G RSQAA+TYLE+ FESF
Sbjct: 121 IQFAGKRPFGVGLLIAGYDSTGPHLYHTVPSGDVFDFKATAMGLRSQAARTYLEKHFESF 180
Query: 629 GDSSKEDLIKDAILAV-RETLQGETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKV 805
D ++LI A+ A+ T G L T++++G G PF L +E +K +D F+
Sbjct: 181 PDCGLDELIMHALKALAAATSGGAELNIKNTTIAIVGKGTPFMVLTEEAARKYLDGFKMR 240
Query: 806 PEEEEGEAGEGEAEAAPAEQGGD 874
PE+ A E E E E+ D
Sbjct: 241 PEDIP-PAPEAEEEETLQERSLD 262
>sp|O96788|PSA1_TRYBR Proteasome subunit alpha type-1 OS=Trypanosoma brucei
rhodesiense PE=2 SV=1
Length = 266
Score = 225 bits (571), Expect = 8e-058
Identities = 120/263 (45%), Positives = 168/263 (63%), Gaps = 2/263 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNK-AQSELSSH 268
MF+NQYDTD TTWSPTGRLFQVEYA EAV GSAA+G++ +VVL + + S LSS+
Sbjct: 1 MFKNQYDTDTTTWSPTGRLFQVEYANEAVNNGSAAVGVKGADYVVLTALKRNPVSGLSSY 60
Query: 269 QKKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVC 448
Q+K FK+D+H+G+AI+GL ADGR LSR++R+E +N+ + ++S P+ L + K Q
Sbjct: 61 QEKAFKLDEHVGMAISGLVADGRALSRFLRTECMNYRYMHDSDAPLVMLADIVGAKHQRH 120
Query: 449 TQRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESF 628
Q + KRP+GVGLL+ G D G LY PSG+ F+++A A+G RSQAA+TYLER F F
Sbjct: 121 IQFAGKRPFGVGLLIAGYDRQGPRLYQTVPSGDVFDFKATAMGLRSQAARTYLERHFRGF 180
Query: 629 GDSSKEDLIKDAILAV-RETLQGETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKV 805
++L+ A+ A+ T G L T++++G G PF L +E +K +D F+
Sbjct: 181 PACDLDELVMHALRALGAATSGGVELNIKNTTIAIVGKGTPFTILTEEEARKYLDGFKTR 240
Query: 806 PEEEEGEAGEGEAEAAPAEQGGD 874
PE+ A E + EQ D
Sbjct: 241 PEDIPAVADNEEDDDELHEQPPD 263
>sp|O44156|PSA1_CAEEL Proteasome subunit alpha type-1 OS=Caenorhabditis elegans
GN=pas-6 PE=1 SV=1
Length = 260
Score = 221 bits (562), Expect = 9e-057
Identities = 111/256 (43%), Positives = 165/256 (64%), Gaps = 5/256 (1%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRNQYD DVT WSP GRL QVEYA+EA+KQGSA +G++S +H V+ + +AQ++LSSHQ
Sbjct: 1 MFRNQYDGDVTVWSPQGRLHQVEYAVEAMKQGSATVGIKSETHAVIVALKRAQNDLSSHQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KK++++D H GV+IAGL +DGR+L+RY+++E + + Y+ +P+ +L + K Q T
Sbjct: 61 KKVYEIDTHAGVSIAGLLSDGRILARYLQTECSSWRWDYKQAVPIKKLAESMQLKLQANT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFG 631
Q +RP+GVG+L+ G D+ GAH+ PS +IG+RSQ+A+TYLER ++F
Sbjct: 121 QYYGRRPFGVGILIAGYDKDGAHIIQTDPSAEVVSMHGTSIGARSQSARTYLERNVDNFE 180
Query: 632 DSSKEDLIKDAILAVRETLQG-ETLKSSLCTVSVLGVGEPFHFLDQETIQKVIDTFEKVP 808
S+ E LI A+LA+R+TL E L + ++ ++G PF L+ + ++ P
Sbjct: 181 KSTPEQLIVHALLALRDTLPAEENLNAQNTSIGIVGKDSPFSLLEDAQVAVHLNQVSTHP 240
Query: 809 EEEEGEAGEGEAEAAP 856
G A A AAP
Sbjct: 241 RTTGGAA----AAAAP 252
>sp|P40302|PSA1_YEAST Proteasome component PRE5 OS=Saccharomyces cerevisiae
GN=PRE5 PE=1 SV=1
Length = 234
Score = 215 bits (546), Expect = 6e-055
Identities = 115/234 (49%), Positives = 151/234 (64%), Gaps = 2/234 (0%)
Frame = +2
Query: 92 MFRNQYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ 271
MFRN YD D T+SPTGRLFQVEYA+EA+KQGS +GLRS +H VL + + ELSS+Q
Sbjct: 1 MFRNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQ 60
Query: 272 KKIFKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCT 451
KKI K D+H+G+++AGL D RVLS Y+R + S + L V R L DKAQ T
Sbjct: 61 KKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNT 120
Query: 452 QRSWKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESF- 628
Q RPYGVGLL+ G D+SGAHL PSGN E AIG+RSQ AKTYLER ++F
Sbjct: 121 QSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFI 180
Query: 629 -GDSSKEDLIKDAILAVRETLQGETLKSSLCTVSVLGVGEPFHFLDQETIQKVI 787
D + ++LIK + A+ ++L+ E+L +++++G PF D E + K I
Sbjct: 181 KIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 234
>sp|C3N5R0|PSMA_SULIA Proteasome subunit alpha OS=Sulfolobus islandicus (strain
M.16.27) GN=psmA PE=3 SV=1
Length = 241
Score = 153 bits (385), Expect = 3e-036
Identities = 89/215 (41%), Positives = 125/215 (58%), Gaps = 10/215 (4%)
Frame = +2
Query: 107 YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLAC-VNKAQSELSSHQ-KKI 280
YD +T +SP G L+QV+YA EAVK+G AIG++S+S VV+A KAQS L +K+
Sbjct: 10 YDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSGVVIASEKRKAQSLLDVDSIEKV 69
Query: 281 FKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCTQRS 460
F +DDH+G + AGL +DGRVL Y R+ A+ H Y+ P+ + L +AD Q+ TQ
Sbjct: 70 FLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVADVKQMYTQHG 129
Query: 461 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSS 640
RP+GV L++ G+D+S LY PSG Y YQA AIG A +LE+ +
Sbjct: 130 GVRPFGVALVIAGIDKSVPKLYMTEPSGQYMPYQAVAIGQGYYTATEFLEKNY------- 182
Query: 641 KEDL-IKDAILAVRETLQGETLKSSLCTVSVLGVG 742
KEDL I+D IL + L + T + + +G
Sbjct: 183 KEDLTIEDTILLALKALSATLKPNEKLTPNTVEIG 217
>sp|C4KHD9|PSMA_SULIK Proteasome subunit alpha OS=Sulfolobus islandicus (strain
M.16.4 / Kamchatka #3) GN=psmA PE=3 SV=1
Length = 241
Score = 153 bits (385), Expect = 3e-036
Identities = 89/215 (41%), Positives = 125/215 (58%), Gaps = 10/215 (4%)
Frame = +2
Query: 107 YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLAC-VNKAQSELSSHQ-KKI 280
YD +T +SP G L+QV+YA EAVK+G AIG++S+S VV+A KAQS L +K+
Sbjct: 10 YDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSGVVIASEKRKAQSLLDVDSIEKV 69
Query: 281 FKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCTQRS 460
F +DDH+G + AGL +DGRVL Y R+ A+ H Y+ P+ + L +AD Q+ TQ
Sbjct: 70 FLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVADVKQMYTQHG 129
Query: 461 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSS 640
RP+GV L++ G+D+S LY PSG Y YQA AIG A +LE+ +
Sbjct: 130 GVRPFGVALVIAGIDKSVPKLYMTEPSGQYMPYQAVAIGQGYYTATEFLEKNY------- 182
Query: 641 KEDL-IKDAILAVRETLQGETLKSSLCTVSVLGVG 742
KEDL I+D IL + L + T + + +G
Sbjct: 183 KEDLTIEDTILLALKALSATLKPNEKLTPNTVEIG 217
>sp|C3MQ43|PSMA_SULIL Proteasome subunit alpha OS=Sulfolobus islandicus (strain
L.S.2.15 / Lassen #1) GN=psmA PE=3 SV=1
Length = 241
Score = 153 bits (385), Expect = 3e-036
Identities = 89/215 (41%), Positives = 125/215 (58%), Gaps = 10/215 (4%)
Frame = +2
Query: 107 YDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLAC-VNKAQSELSSHQ-KKI 280
YD +T +SP G L+QV+YA EAVK+G AIG++S+S VV+A KAQS L +K+
Sbjct: 10 YDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSGVVIASEKRKAQSLLDVDSIEKV 69
Query: 281 FKVDDHIGVAIAGLTADGRVLSRYMRSEAINHSFTYESPLPVGRLVVHLADKAQVCTQRS 460
F +DDH+G + AGL +DGRVL Y R+ A+ H Y+ P+ + L +AD Q+ TQ
Sbjct: 70 FLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVADVKQMYTQHG 129
Query: 461 WKRPYGVGLLVGGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSS 640
RP+GV L++ G+D+S LY PSG Y YQA AIG A +LE+ +
Sbjct: 130 GVRPFGVALVIAGIDKSVPKLYMTEPSGQYMPYQAVAIGQGYYTATEFLEKNY------- 182
Query: 641 KEDL-IKDAILAVRETLQGETLKSSLCTVSVLGVG 742
KEDL I+D IL + L + T + + +G
Sbjct: 183 KEDLTIEDTILLALKALSATLKPNEKLTPNTVEIG 217
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,908,948,754
Number of Sequences: 518415
Number of Extensions: 78908948754
Number of Successful Extensions: 532487479
Number of sequences better than 0.0: 0
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