BLASTX 7.6.2
Query= UN19415 /QuerySize=1567
(1566 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R6T1|PDIA6_PONAB Protein disulfide-isomerase A6 OS=Pongo ab... 369 5e-101
sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 OS=Homo sap... 368 9e-101
sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 OS=Mus musc... 363 2e-099
sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 OS=Rattus nor... 361 8e-099
sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 OS... 247 2e-064
sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 OS=Mesocric... 203 4e-051
sp|Q869Z0|Y5025_DICDI Putative protein disulfide-isomerase DDB_G... 112 9e-024
sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 OS=Mus musc... 106 6e-022
sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 OS=Bos taur... 105 1e-021
sp|Q4VIT4|PDIA3_CERAE Protein disulfide-isomerase A3 OS=Cercopit... 104 3e-021
sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 OS=Homo sap... 103 4e-021
sp|Q8JG64|PDIA3_CHICK Protein disulfide-isomerase A3 OS=Gallus g... 103 5e-021
>sp|Q5R6T1|PDIA6_PONAB Protein disulfide-isomerase A6 OS=Pongo abelii GN=PDIA6
PE=2 SV=1
Length = 440
Score = 369 bits (945), Expect = 5e-101
Identities = 194/444 (43%), Positives = 274/444 (61%), Gaps = 14/444 (3%)
Frame = +3
Query: 78 LTLLTLLSLLLGFLNLTNALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKA 257
+ LL L + F N LY SS V++LT SNF +V+ S+ + LVEF+APWCGHC+
Sbjct: 1 MALLVLGLVSCAFFLEVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR 60
Query: 258 LTPTWEKVATVLKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGK-PPVDYQGARDA 434
LTP W+K AT LK V V A+DAD H S YG+QGFPTIK+F K P DYQG R
Sbjct: 61 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG 120
Query: 435 KSIANFAYKQIKALLSDRLEGKSKPTGGSNEKKSEPSAS---VELNSANFDELVIKSNDL 605
++I + A ++ L+ DRL G+S + +S+ S+ +EL +FD+ V+ S D+
Sbjct: 121 EAIVDAALSALRQLVKDRLGGQSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV 180
Query: 606 WIVEFFAPWCGHCKKLAPEWKRAAKNL----KGKVKLGHVNCDVEQSIMSRFKVQGFPTI 773
W+VEF+APWCGHCK L PEW AA + KGKVKL V+ V Q + SR+ ++GFPTI
Sbjct: 181 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI 240
Query: 774 MVFGVDKSSPYAYDGARSASAIESFATELVESSAGPVEVTELTGPDVMEKKCGSAAICFV 953
+F + SP YDG R+ S I S A +L +A P E+ E+ D+ ++ C +C V
Sbjct: 241 KIFQKGE-SPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIISEDIAKRTCEEHQLCVV 299
Query: 954 SFLPDILDSKAEGRNKYLDMLLSVAEKFKRHPYSFVWVAAVTQPDLEKKVNVGGYGYPAM 1133
S LP ILD+ A GRN YL++LL +A+K+K+ + ++W A Q +LE + +GG+GYPAM
Sbjct: 300 SVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAM 359
Query: 1134 VAMNVKKAVYAPLKSAFELQHLLEFVKDAGAGGKGNVPMNG--TPEIVETKAWDGKDGEV 1307
A+N +K +A LK +F Q + EF+++ G P+ G P IVE + WDG+DGE+
Sbjct: 360 AAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGEL 419
Query: 1308 IEEDEFSLEELMGGDDNVGTKDEL 1379
ED+ L ++ D++G KDEL
Sbjct: 420 PVEDDIDLSDV--ELDDLG-KDEL 440
>sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 OS=Homo sapiens GN=PDIA6
PE=1 SV=1
Length = 440
Score = 368 bits (943), Expect = 9e-101
Identities = 193/444 (43%), Positives = 274/444 (61%), Gaps = 14/444 (3%)
Frame = +3
Query: 78 LTLLTLLSLLLGFLNLTNALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKA 257
+ LL L + F N LY SS V++LT SNF +V+ S+ + LVEF+APWCGHC+
Sbjct: 1 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQR 60
Query: 258 LTPTWEKVATVLKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGK-PPVDYQGARDA 434
LTP W+K AT LK V V A+DAD H S YG+QGFPTIK+F K P DYQG R
Sbjct: 61 LTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTG 120
Query: 435 KSIANFAYKQIKALLSDRLEGKSKPTGGSNEKKSEPSAS---VELNSANFDELVIKSNDL 605
++I + A ++ L+ DRL G+S + +S+ S+ +EL +FD+ V+ S D+
Sbjct: 121 EAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV 180
Query: 606 WIVEFFAPWCGHCKKLAPEWKRAAKNL----KGKVKLGHVNCDVEQSIMSRFKVQGFPTI 773
W+VEF+APWCGHCK L PEW AA + KGKVKL V+ V Q + SR+ ++GFPTI
Sbjct: 181 WMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTI 240
Query: 774 MVFGVDKSSPYAYDGARSASAIESFATELVESSAGPVEVTELTGPDVMEKKCGSAAICFV 953
+F + SP YDG R+ S I S A +L +A P E+ E+ D+ ++ C +C V
Sbjct: 241 KIFQKGE-SPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVV 299
Query: 954 SFLPDILDSKAEGRNKYLDMLLSVAEKFKRHPYSFVWVAAVTQPDLEKKVNVGGYGYPAM 1133
+ LP ILD+ A GRN YL++LL +A+K+K+ + ++W A Q +LE + +GG+GYPAM
Sbjct: 300 AVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAM 359
Query: 1134 VAMNVKKAVYAPLKSAFELQHLLEFVKDAGAGGKGNVPMNG--TPEIVETKAWDGKDGEV 1307
A+N +K +A LK +F Q + EF+++ G P+ G P IVE + WDG+DGE+
Sbjct: 360 AAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGEL 419
Query: 1308 IEEDEFSLEELMGGDDNVGTKDEL 1379
ED+ L ++ D++G KDEL
Sbjct: 420 PVEDDIDLSDV--ELDDLG-KDEL 440
>sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 OS=Mus musculus GN=Pdia6
PE=1 SV=3
Length = 440
Score = 363 bits (931), Expect = 2e-099
Identities = 187/428 (43%), Positives = 265/428 (61%), Gaps = 16/428 (3%)
Frame = +3
Query: 102 LLLGFLNLT-----NALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTP 266
L+LG ++ T + LY SS V++LT SNF +V+ S+G+ LVEF+APWCGHC+ LTP
Sbjct: 4 LVLGLVSCTFFLAVSGLYSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTP 63
Query: 267 TWEKVATVLKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGK-PPVDYQGARDAKSI 443
W+K AT LK V V A++AD HQS YG+QGFPTIK+F K P DYQG R ++I
Sbjct: 64 EWKKAATALKDVVKVGAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAI 123
Query: 444 ANFAYKQIKALLSDRLEGKSKPTGGSNEKKSEPSAS---VELNSANFDELVIKSNDLWIV 614
+ A ++ L+ DRL G+S + + + S+ VEL FD+ V+ S D+W+V
Sbjct: 124 VDAALSALRQLVKDRLGGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMV 183
Query: 615 EFFAPWCGHCKKLAPEWKRAA----KNLKGKVKLGHVNCDVEQSIMSRFKVQGFPTIMVF 782
EF+APWCGHCK L PEW AA + KGKVKL V+ V Q + SR+ ++GFPTI +F
Sbjct: 184 EFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIF 243
Query: 783 GVDKSSPYAYDGARSASAIESFATELVESSAGPVEVTELTGPDVMEKKCGSAAICFVSFL 962
+ SP YDG R+ S I S A +L +A P E+ E+ D+ +K C +C V+ L
Sbjct: 244 QKGE-SPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVL 302
Query: 963 PDILDSKAEGRNKYLDMLLSVAEKFKRHPYSFVWVAAVTQPDLEKKVNVGGYGYPAMVAM 1142
P ILD+ A GRN YL++LL +A+K+K+ + ++W A Q +LE + +GG+GYPAM A+
Sbjct: 303 PHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAI 362
Query: 1143 NVKKAVYAPLKSAFELQHLLEFVKDAGAGGKGNVPMNG--TPEIVETKAWDGKDGEVIEE 1316
N +K +A LK +F Q + EF+++ G P+ G P I + WDGKDGE+ E
Sbjct: 363 NARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPTITPREPWDGKDGELPVE 422
Query: 1317 DEFSLEEL 1340
D+ L ++
Sbjct: 423 DDIDLSDV 430
>sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 OS=Rattus norvegicus
GN=Pdia6 PE=1 SV=2
Length = 440
Score = 361 bits (926), Expect = 8e-099
Identities = 186/428 (43%), Positives = 265/428 (61%), Gaps = 16/428 (3%)
Frame = +3
Query: 102 LLLGFLNLT-----NALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTP 266
L+LG ++ T +ALY SS V++LT SNF +V+ S+ + LVEF+APWCGHC+ LTP
Sbjct: 4 LVLGLVSCTFFLAVSALYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTP 63
Query: 267 TWEKVATVLKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGK-PPVDYQGARDAKSI 443
W+K A+ LK V V A++AD HQS YG+QGFPTIK+F K P DYQG R ++I
Sbjct: 64 EWKKAASALKDVVKVGAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAI 123
Query: 444 ANFAYKQIKALLSDRLEGKSKPTGGSNEKKSEPSAS---VELNSANFDELVIKSNDLWIV 614
+ A ++ L+ DRL G+S + + + S+ VEL FD+ V+ S D+W+V
Sbjct: 124 VDAALSALRQLVKDRLGGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMV 183
Query: 615 EFFAPWCGHCKKLAPEWKRAA----KNLKGKVKLGHVNCDVEQSIMSRFKVQGFPTIMVF 782
EF+APWCGHCK L PEW AA + KGKVKL V+ V Q + SR+ ++GFPTI +F
Sbjct: 184 EFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIF 243
Query: 783 GVDKSSPYAYDGARSASAIESFATELVESSAGPVEVTELTGPDVMEKKCGSAAICFVSFL 962
+ SP YDG R+ S I S A +L +A P E+ E+ D+ +K C +C V+ L
Sbjct: 244 QKGE-SPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVL 302
Query: 963 PDILDSKAEGRNKYLDMLLSVAEKFKRHPYSFVWVAAVTQPDLEKKVNVGGYGYPAMVAM 1142
P ILD+ A GRN YL++LL +A+K+K+ + ++W A Q +LE + +GG+GYPAM A+
Sbjct: 303 PHILDTGATGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAI 362
Query: 1143 NVKKAVYAPLKSAFELQHLLEFVKDAGAGGKGNVPMNG--TPEIVETKAWDGKDGEVIEE 1316
N +K +A LK +F Q + EF+++ G P+ G P I + WDGKDGE+ E
Sbjct: 363 NARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPNITPREPWDGKDGELPVE 422
Query: 1317 DEFSLEEL 1340
D+ L ++
Sbjct: 423 DDIDLSDV 430
>sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 OS=Caenorhabditis
elegans GN=tag-320 PE=2 SV=1
Length = 440
Score = 247 bits (630), Expect = 2e-064
Identities = 130/311 (41%), Positives = 182/311 (58%), Gaps = 8/311 (2%)
Frame = +3
Query: 432 AKSIANFAYKQIKALLSDRLEGKSKPTGGSNEKKSEPSAS----VELNSANFDELVIKSN 599
A S+ A K + A L + G S GS K S VEL ANF++LV+ S
Sbjct: 123 ADSVLAEAKKAVSARLGGKSSGSSSSGSGSGSGKRGGGGSGNEVVELTDANFEDLVLNSK 182
Query: 600 DLWIVEFFAPWCGHCKKLAPEWKRAAKNLKGKVKLGHVNCDVEQSIMSRFKVQGFPTIMV 779
D+W+VEFFAPWCGHCK L P+WK AA LKGKV+LG ++ V + ++F ++GFPTI
Sbjct: 183 DIWLVEFFAPWCGHCKSLEPQWKAAASELKGKVRLGALDATVHTVVANKFAIRGFPTIKY 242
Query: 780 F--GVDKSSPYAYDGARSASAIESFATELVESSAGPVEVTELTGPDVMEKKCGSAAICFV 953
F G D S YDG R +S I ++A+ + + EV E V+E C +C
Sbjct: 243 FAPGSDVSDAQDYDGGRQSSDIVAWASARAQENMPAPEVFEGINQQVVEDACKEKQLCIF 302
Query: 954 SFLPDILDSKAEGRNKYLDMLLSVAEKFKRHPYSFVWVAAVTQPDLEKKVNVGGYGYPAM 1133
+FLP ILD ++E RN YL ML +EKFK++ + ++WV QP LE+ VGG+GYPAM
Sbjct: 303 AFLPHILDCQSECRNNYLAMLKEQSEKFKKNLWGWIWVEGAAQPALEESFEVGGFGYPAM 362
Query: 1134 VAMNVKKAVYAPLKSAFELQHLLEFVKDA--GAGGKGNVPMNGTPEIVETKAWDGKDGEV 1307
A+N +K YA LK +F + EF++D G G ++ +G P+I +T+ WDGKDG +
Sbjct: 363 TALNFRKNKYAVLKGSFGKDGIHEFLRDLSYGKGRTSSLRGDGFPKIQKTEKWDGKDGAL 422
Query: 1308 IEEDEFSLEEL 1340
ED+ L ++
Sbjct: 423 PAEDDIDLSDI 433
Score = 138 bits (347), Expect = 1e-031
Identities = 69/148 (46%), Positives = 96/148 (64%), Gaps = 3/148 (2%)
Frame = +3
Query: 87 LTLLSLLLGFLNLTN--ALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKAL 260
+ L+ LLL L +T+ +Y VV+LT +NF+SKV+NS+ + +VEF+APWCGHCK+L
Sbjct: 1 MALIKLLLASLAITSVCGMYSKKDDVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSL 60
Query: 261 TPTWEKVATVLKGVATVAALDADAHQSAAQDYGIQGFPTIKVF-VPGKPPVDYQGARDAK 437
P ++K A+ LKGVA V A+D HQS Y +QGFPT+K+F K P DY G R A+
Sbjct: 61 VPEYKKAASALKGVAKVGAVDMTQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQ 120
Query: 438 SIANFAYKQIKALLSDRLEGKSKPTGGS 521
+IA+ + K +S RL GKS + S
Sbjct: 121 AIADSVLAEAKKAVSARLGGKSSGSSSS 148
Score = 120 bits (299), Expect = 4e-026
Identities = 54/96 (56%), Positives = 67/96 (69%)
Frame = +3
Query: 552 VELNSANFDELVIKSNDLWIVEFFAPWCGHCKKLAPEWKRAAKNLKGKVKLGHVNCDVEQ 731
VEL ANF VI S+D+WIVEF+APWCGHCK L PE+K+AA LKG K+G V+ Q
Sbjct: 27 VELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALKGVAKVGAVDMTQHQ 86
Query: 732 SIMSRFKVQGFPTIMVFGVDKSSPYAYDGARSASAI 839
S+ + VQGFPT+ +FG DK P Y+G R+A AI
Sbjct: 87 SVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQAI 122
Score = 111 bits (275), Expect = 3e-023
Identities = 54/108 (50%), Positives = 67/108 (62%), Gaps = 3/108 (2%)
Frame = +3
Query: 141 GSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTPTWEKVATVLKGVATVAAL 320
GS + VV+LT +NF+ VLNS + LVEFFAPWCGHCK+L P W+ A+ LKG + AL
Sbjct: 161 GSGNEVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCKSLEPQWKAAASELKGKVRLGAL 220
Query: 321 DADAHQSAAQDYGIQGFPTIKVFVPG---KPPVDYQGARDAKSIANFA 455
DA H A + I+GFPTIK F PG DY G R + I +A
Sbjct: 221 DATVHTVVANKFAIRGFPTIKYFAPGSDVSDAQDYDGGRQSSDIVAWA 268
>sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 OS=Mesocricetus auratus
GN=PDIA6 PE=1 SV=1
Length = 439
Score = 203 bits (515), Expect = 4e-051
Identities = 96/200 (48%), Positives = 128/200 (64%), Gaps = 4/200 (2%)
Frame = +3
Query: 114 FLNLTNALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTPTWEKVATVL 293
F + LY SS V++LT SNF +V+ SN + LVEF+APWCGHC+ LTP W+K AT L
Sbjct: 13 FFLAASGLYSSSDDVIELTPSNFNREVIQSNSLWLVEFYAPWCGHCQRLTPEWKKAATAL 72
Query: 294 KGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGK-PPVDYQGARDAKSIANFAYKQIK 470
K V V A+DAD HQS YG+QGFPTIK+F K P DYQG R ++I + A ++
Sbjct: 73 KDVVKVGAVDADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALR 132
Query: 471 ALLSDRLEGKSKPTGGSNEKKSEPSAS---VELNSANFDELVIKSNDLWIVEFFAPWCGH 641
L+ DRL G+S + + + S+ +EL FD+ V+ S+D+W+VEF+APWCGH
Sbjct: 133 QLVKDRLSGRSGGYSSGKQGRGDSSSKKDVIELTDDTFDKNVLDSDDVWMVEFYAPWCGH 192
Query: 642 CKKLAPEWKRAAKNLKGKVK 701
CK L PEW AA +K + K
Sbjct: 193 CKNLEPEWATAATEVKEQTK 212
Score = 120 bits (299), Expect = 4e-026
Identities = 52/96 (54%), Positives = 70/96 (72%)
Frame = +3
Query: 552 VELNSANFDELVIKSNDLWIVEFFAPWCGHCKKLAPEWKRAAKNLKGKVKLGHVNCDVEQ 731
+EL +NF+ VI+SN LW+VEF+APWCGHC++L PEWK+AA LK VK+G V+ D Q
Sbjct: 28 IELTPSNFNREVIQSNSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHQ 87
Query: 732 SIMSRFKVQGFPTIMVFGVDKSSPYAYDGARSASAI 839
S+ ++ VQGFPTI +FG +K+ P Y G R+ AI
Sbjct: 88 SLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAI 123
>sp|Q869Z0|Y5025_DICDI Putative protein disulfide-isomerase DDB_G0275025
OS=Dictyostelium discoideum GN=DDB_G0275025 PE=1 SV=1
Length = 409
Score = 112 bits (279), Expect = 9e-024
Identities = 50/118 (42%), Positives = 74/118 (62%), Gaps = 5/118 (4%)
Frame = +3
Query: 534 SEPSASVELNSANFDELVIKSNDLWIVEFFAPWCGHCKKLAPEWKRAAKNLKGKVKLGHV 713
++ S + L NF + V+ S W+VEF+APWCGHCK L PE+++ + NLKG VK+G +
Sbjct: 24 TDNSNVINLTKKNFQQQVLNSQQNWMVEFYAPWCGHCKSLKPEYEKVSNNLKGLVKIGAI 83
Query: 714 NCDVEQSIMSRFKVQGFPTIMVFGVD-----KSSPYAYDGARSASAIESFATELVESS 872
NCD E+ + ++++QGFPT+ F + K P Y GARSAS I F+ + S+
Sbjct: 84 NCDEEKELCGQYQIQGFPTLKFFSTNPKTGKKGQPEDYQGARSASEIAKFSLAKLPSN 141
Score = 107 bits (267), Expect = 2e-022
Identities = 55/120 (45%), Positives = 73/120 (60%), Gaps = 6/120 (5%)
Frame = +3
Query: 126 TNALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTPTWEKVATVLKGVA 305
T Y +S V+ LT NF+ +VLNS +VEF+APWCGHCK+L P +EKV+ LKG+
Sbjct: 19 TFGFYTDNSNVINLTKKNFQQQVLNSQQNWMVEFYAPWCGHCKSLKPEYEKVSNNLKGLV 78
Query: 306 TVAALDADAHQSAAQDYGIQGFPTIKVF----VPGK--PPVDYQGARDAKSIANFAYKQI 467
+ A++ D + Y IQGFPT+K F GK P DYQGAR A IA F+ ++
Sbjct: 79 KIGAINCDEEKELCGQYQIQGFPTLKFFSTNPKTGKKGQPEDYQGARSASEIAKFSLAKL 138
>sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 OS=Mus musculus GN=Pdia3
PE=1 SV=2
Length = 505
Score = 106 bits (263), Expect = 6e-022
Identities = 56/126 (44%), Positives = 78/126 (61%), Gaps = 3/126 (2%)
Frame = +3
Query: 96 LSLLLGF-LNLTNALYGSSSPVVQLTASNFKSKV--LNSNGVVLVEFFAPWCGHCKALTP 266
L+LL G L L +A ++S V++LT NF+S+V S G++LVEFFAPWCGHCK L P
Sbjct: 6 LALLPGVALLLASARLAAASDVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAP 65
Query: 267 TWEKVATVLKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGKPPVDYQGARDAKSIA 446
+E AT LKG+ +A +D A+ + YG+ G+PT+K+F G+ Y G R A I
Sbjct: 66 EYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIV 125
Query: 447 NFAYKQ 464
+ KQ
Sbjct: 126 SHLKKQ 131
>sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 OS=Bos taurus GN=PDIA3
PE=2 SV=1
Length = 505
Score = 105 bits (261), Expect = 1e-021
Identities = 55/129 (42%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
Frame = +3
Query: 87 LTLLSLLLGF-LNLTNALYGSSSPVVQLTASNFKSKVLN--SNGVVLVEFFAPWCGHCKA 257
L L+L G L L A ++S V++LT NF+S++ + S+G++LVEFFAPWCGHCK
Sbjct: 3 LRRLALFPGLALLLAAARLAAASDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKK 62
Query: 258 LTPTWEKVATVLKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGKPPVDYQGARDAK 437
L P +E AT LKG+ +A +D A+ + YG+ G+PT+K+F G+ Y G R A
Sbjct: 63 LAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTAD 122
Query: 438 SIANFAYKQ 464
I + KQ
Sbjct: 123 GIVSHLKKQ 131
>sp|Q4VIT4|PDIA3_CERAE Protein disulfide-isomerase A3 OS=Cercopithecus aethiops
GN=PDIA3 PE=2 SV=1
Length = 505
Score = 104 bits (257), Expect = 3e-021
Identities = 52/118 (44%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 117 LNLTNALYGSSSPVVQLTASNFKSKV--LNSNGVVLVEFFAPWCGHCKALTPTWEKVATV 290
L L A ++S V++LT NF+S+V S G++LVEFFAPWCGHCK L P +E AT
Sbjct: 14 LLLAAARLAAASDVLELTDDNFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATR 73
Query: 291 LKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGKPPVDYQGARDAKSIANFAYKQ 464
LKG+ +A +D A+ + YG+ G+PT+K+F G+ Y G R A I + KQ
Sbjct: 74 LKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131
>sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 OS=Homo sapiens GN=PDIA3
PE=1 SV=4
Length = 505
Score = 103 bits (256), Expect = 4e-021
Identities = 51/118 (43%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
Frame = +3
Query: 117 LNLTNALYGSSSPVVQLTASNFKSKV--LNSNGVVLVEFFAPWCGHCKALTPTWEKVATV 290
L L A ++S V++LT NF+S++ S G++LVEFFAPWCGHCK L P +E AT
Sbjct: 14 LLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATR 73
Query: 291 LKGVATVAALDADAHQSAAQDYGIQGFPTIKVFVPGKPPVDYQGARDAKSIANFAYKQ 464
LKG+ +A +D A+ + YG+ G+PT+K+F G+ Y G R A I + KQ
Sbjct: 74 LKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131
>sp|Q8JG64|PDIA3_CHICK Protein disulfide-isomerase A3 OS=Gallus gallus GN=PDIA3
PE=2 SV=1
Length = 505
Score = 103 bits (255), Expect = 5e-021
Identities = 48/111 (43%), Positives = 68/111 (61%)
Frame = +3
Query: 132 ALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTPTWEKVATVLKGVATV 311
AL +S VV+L+ ++F+S + G+VLVEFFAPWCGHCK L P +E AT LKG+ +
Sbjct: 19 ALSAGASDVVELSDADFESGLAERPGLVLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPL 78
Query: 312 AALDADAHQSAAQDYGIQGFPTIKVFVPGKPPVDYQGARDAKSIANFAYKQ 464
+D A+ + YG+ G+PT+K+F G+ Y G R A I + KQ
Sbjct: 79 VKVDCTANSNTCNKYGVSGYPTLKIFRDGEESGTYDGPRTADGIVSHLKKQ 129
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,908,948,754
Number of Sequences: 518415
Number of Extensions: 78908948754
Number of Successful Extensions: 532487479
Number of sequences better than 0.0: 0
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