BLASTX 7.6.2
Query= UN19465 /QuerySize=1355
(1354 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CQU8|IMP1L_MOUSE Mitochondrial inner membrane protease subu... 126 5e-028
sp|Q96LU5|IMP1L_HUMAN Mitochondrial inner membrane protease subu... 124 1e-027
sp|Q28I39|IMP1L_XENTR Mitochondrial inner membrane protease subu... 121 2e-026
sp|O74800|IMP1_SCHPO Mitochondrial inner membrane protease subun... 108 1e-022
sp|P46972|IMP2_YEAST Mitochondrial inner membrane protease subun... 87 3e-016
sp|Q2KI92|IMP2L_BOVIN Mitochondrial inner membrane protease subu... 86 4e-016
sp|Q6AZD4|IMP2L_DANRE Mitochondrial inner membrane protease subu... 86 7e-016
sp|Q96T52|IMP2L_HUMAN Mitochondrial inner membrane protease subu... 82 6e-015
sp|Q8BPT6|IMP2L_MOUSE Mitochondrial inner membrane protease subu... 82 8e-015
sp|Q5PQ63|IMP2L_XENLA Mitochondrial inner membrane protease subu... 77 2e-013
sp|Q9UST2|IMP2L_SCHPO Mitochondrial inner membrane protease subu... 67 4e-010
sp|P28627|IMP1_YEAST Mitochondrial inner membrane protease subun... 55 1e-006
>sp|Q9CQU8|IMP1L_MOUSE Mitochondrial inner membrane protease subunit 1 OS=Mus
musculus GN=Immp1l PE=2 SV=1
Length = 166
Score = 126 bits (315), Expect = 5e-028
Identities = 66/157 (42%), Positives = 90/157 (57%), Gaps = 5/157 (3%)
Frame = +1
Query: 625 RGTAKEAFEQVSIVAKFLCLIHVTDRYIISSTHVQGPSMLPTLNLTGDVILAEHLSHRFG 804
RG +AF ++ C+ H Y+ GPSM PT+ D++ AE+LS F
Sbjct: 3 RGVLGKAFRLAGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQ-NSDIVFAENLSRHFY 61
Query: 805 KIGLGDIVLVRSPTDPTRMVTKRILGLEGHR-LSFSADPLLGDSSVSVVVPKGHVWIQGD 981
I GDIV+ +SP+DP + KR++GLEG + LS S + S VP GHVW++GD
Sbjct: 62 GIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILSTSPSDVFKSRS---YVPTGHVWLEGD 118
Query: 982 NLYASTDSRNFGPVPYNLIEGKALLRVWPPRFFGSLR 1092
NL STDSR +GP+PY LI G+ ++WP FG LR
Sbjct: 119 NLQNSTDSRYYGPIPYGLIRGRIFFKIWPFSDFGFLR 155
>sp|Q96LU5|IMP1L_HUMAN Mitochondrial inner membrane protease subunit 1 OS=Homo
sapiens GN=IMMP1L PE=2 SV=1
Length = 166
Score = 124 bits (311), Expect = 1e-027
Identities = 65/157 (41%), Positives = 89/157 (56%), Gaps = 5/157 (3%)
Frame = +1
Query: 625 RGTAKEAFEQVSIVAKFLCLIHVTDRYIISSTHVQGPSMLPTLNLTGDVILAEHLSHRFG 804
RG + F V ++ C+ H Y+ GPSM PT+ D++ AE+LS F
Sbjct: 3 RGVLGKTFRLVGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQ-NSDIVFAENLSRHFY 61
Query: 805 KIGLGDIVLVRSPTDPTRMVTKRILGLEGHR-LSFSADPLLGDSSVSVVVPKGHVWIQGD 981
I GDIV+ +SP+DP + KR++GLEG + L+ S S VP GHVW++GD
Sbjct: 62 GIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILTTSPSDFFKSHS---YVPMGHVWLEGD 118
Query: 982 NLYASTDSRNFGPVPYNLIEGKALLRVWPPRFFGSLR 1092
NL STDSR +GP+PY LI G+ ++WP FG LR
Sbjct: 119 NLQNSTDSRCYGPIPYGLIRGRIFFKIWPLSDFGFLR 155
>sp|Q28I39|IMP1L_XENTR Mitochondrial inner membrane protease subunit 1
OS=Xenopus tropicalis GN=immp1l PE=2 SV=1
Length = 167
Score = 121 bits (302), Expect = 2e-026
Identities = 63/138 (45%), Positives = 84/138 (60%), Gaps = 3/138 (2%)
Frame = +1
Query: 679 CLIHVTDRYIISSTHVQGPSMLPTLNLTGDVILAEHLSHRFGKIGLGDIVLVRSPTDPTR 858
C+ H YI GPSM PT+ DV+L ++LS F I GDI++ +SP P+
Sbjct: 21 CIAHCAFEYIGEVVICSGPSMEPTIR-NYDVLLCDNLSRHFFSIHKGDIIVAKSPDKPSV 79
Query: 859 MVTKRILGLEGHRLSFSADPLLGDSSVSVVVPKGHVWIQGDNLYASTDSRNFGPVPYNLI 1038
+ KR++GLEG ++ S+ L VPKGHVW++GDNL STDSR++GPVPY LI
Sbjct: 80 NICKRVIGLEGDKVCMSSPSAL--LKRHTYVPKGHVWLEGDNLDNSTDSRSYGPVPYALI 137
Query: 1039 EGKALLRVWPPRFFGSLR 1092
G+ LRVWP FG L+
Sbjct: 138 RGRICLRVWPLESFGPLK 155
>sp|O74800|IMP1_SCHPO Mitochondrial inner membrane protease subunit 1
OS=Schizosaccharomyces pombe GN=imp1 PE=2 SV=1
Length = 157
Score = 108 bits (269), Expect = 1e-022
Identities = 54/136 (39%), Positives = 78/136 (57%), Gaps = 5/136 (3%)
Frame = +1
Query: 664 VAKFLCLIHVTDRYIISSTHVQGPSMLPTLNLTGDVILAEHLSHRFGK-IGLGDIVLVRS 840
V + +H Y+ GPSM+PTLN G+ +L + L RF + +GD+V+
Sbjct: 11 VVQIAAFVHQIHEYLFQVQMTSGPSMMPTLNSGGEFVLLDKLHGRFARSCSVGDVVVSAK 70
Query: 841 PTDPTRMVTKRILGLEGHRLSFSADPLLGDSSVSVVVPKGHVWIQGDNLYASTDSRNFGP 1020
P+D + V KRI+G+ G + DP S+ + +P GHVW+ GDN+ S DSRN+GP
Sbjct: 71 PSDSKQHVCKRIIGMPGD--TIYVDPT--SSNKKITIPLGHVWLAGDNIAHSLDSRNYGP 126
Query: 1021 VPYNLIEGKALLRVWP 1068
VP LI+ K + RVWP
Sbjct: 127 VPMGLIKAKVIARVWP 142
>sp|P46972|IMP2_YEAST Mitochondrial inner membrane protease subunit 2
OS=Saccharomyces cerevisiae GN=IMP2 PE=1 SV=1
Length = 177
Score = 87 bits (213), Expect = 3e-016
Identities = 48/159 (30%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 628 GTAKEAFEQVSIVAKFLCLIHVTDRYIISSTHVQGPSMLPTLNLTGDVILAEH-LSHRFG 804
G++K I ++ ++ + ++ V+G SM PTLN + + + L +FG
Sbjct: 5 GSSKRFLRNTLIAISWVPVLLTINNNVVHIAQVKGTSMQPTLNPQTETLATDWVLLWKFG 64
Query: 805 -----KIGLGDIVLVRSPTDPTRMVTKRILGLEGHRLSFSADPLLGDSSVSVVVPKGHVW 969
+ DI+L ++PT+P ++ KR+ GL + D V +P+GH+W
Sbjct: 65 VKNPSNLSRDDIILFKAPTNPRKVYCKRVKGLPFDTI----DTKFPYPKPQVNLPRGHIW 120
Query: 970 IQGDNLYASTDSRNFGPVPYNLIEGKALLRVWPPRFFGS 1086
++GDN + S DS FGP+ L+ GKA+ VWPP +G+
Sbjct: 121 VEGDNYFHSIDSNTFGPISSGLVIGKAITIVWPPSRWGT 159
>sp|Q2KI92|IMP2L_BOVIN Mitochondrial inner membrane protease subunit 2 OS=Bos
taurus GN=IMMP2L PE=2 SV=1
Length = 177
Score = 86 bits (212), Expect = 4e-016
Identities = 61/183 (33%), Positives = 93/183 (50%), Gaps = 22/183 (12%)
Frame = +1
Query: 601 WLRYLNQWRGTAKEAFEQVSIVAKFLCLIHVTDRYIISSTHVQGPSMLPTLNLTG----D 768
W+R ++ K F V + FL DR + V+G SM P+LN G D
Sbjct: 7 WVR--RYFKAFCKGFFVAVPVAVTFL------DR-VACVARVEGASMQPSLNPGGSQSSD 57
Query: 769 VILAEHLSHRFGKIGLGDIVLVRSPTDPTRMVTKRILGLEGHRLSFSADPLLGDSSVSVV 948
V+L H R ++ GDIV + SP +P + + KR++ LEG + +G + V
Sbjct: 58 VVLLNHWKVRNFEVQRGDIVSLVSPKNPEQKIIKRVIALEGDIVK-----TMGHKNRYVK 112
Query: 949 VPKGHVWIQGDNLYASTDSRNFGPVPYNLIEGKALLRVWPPRFFGSLR*RSQSGLFPFQL 1128
VP+GH+W++GD+ S DS +FGPV L+ A +WPP+ + L +S L P +L
Sbjct: 113 VPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPKRWQKL----ESVLPPERL 168
Query: 1129 FLQ 1137
+Q
Sbjct: 169 LVQ 171
>sp|Q6AZD4|IMP2L_DANRE Mitochondrial inner membrane protease subunit 2 OS=Danio
rerio GN=immp2l PE=2 SV=1
Length = 183
Score = 86 bits (210), Expect = 7e-016
Identities = 50/120 (41%), Positives = 68/120 (56%), Gaps = 9/120 (7%)
Frame = +1
Query: 724 VQGPSMLPTLNLTG----DVILAEHLSHRFGKIGLGDIVLVRSPTDPTRMVTKRILGLEG 891
V+G SM P+LN G DV+L S R + GDIV V SP +P + + KR++G+EG
Sbjct: 38 VEGASMQPSLNPDGESSPDVVLLNRWSVRNYHVQRGDIVSVLSPKNPQQKIIKRVIGIEG 97
Query: 892 HRLSFSADPLLGDSSVSVVVPKGHVWIQGDNLYASTDSRNFGPVPYNLIEGKALLRVWPP 1071
+ LG + V VP GH+WI+GD+ S DS FGPV L+ G+A +WPP
Sbjct: 98 DFIK-----TLGYKNRYVRVPDGHLWIEGDHHGHSFDSNAFGPVSLGLVHGRASHIIWPP 152
>sp|Q96T52|IMP2L_HUMAN Mitochondrial inner membrane protease subunit 2 OS=Homo
sapiens GN=IMMP2L PE=2 SV=1
Length = 175
Score = 82 bits (202), Expect = 6e-015
Identities = 46/120 (38%), Positives = 68/120 (56%), Gaps = 9/120 (7%)
Frame = +1
Query: 724 VQGPSMLPTLNLTG----DVILAEHLSHRFGKIGLGDIVLVRSPTDPTRMVTKRILGLEG 891
V+G SM P+LN G DV+L H R ++ GDIV + SP +P + + KR++ LEG
Sbjct: 39 VEGASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEG 98
Query: 892 HRLSFSADPLLGDSSVSVVVPKGHVWIQGDNLYASTDSRNFGPVPYNLIEGKALLRVWPP 1071
+ +G + V VP+GH+W++GD+ S DS +FGPV L+ A +WPP
Sbjct: 99 DIVR-----TIGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPP 153
>sp|Q8BPT6|IMP2L_MOUSE Mitochondrial inner membrane protease subunit 2 OS=Mus
musculus GN=Immp2l PE=2 SV=1
Length = 175
Score = 82 bits (201), Expect = 8e-015
Identities = 53/154 (34%), Positives = 79/154 (51%), Gaps = 16/154 (10%)
Frame = +1
Query: 622 WRGTAKEAFEQVSIVAKFLCLIHVTDRYIISSTHVQGPSMLPTLNLTG----DVILAEHL 789
++ K F V + FL DR + V+G SM P+LN G DV+L H
Sbjct: 12 FKAFCKGFFVAVPVAVTFL------DR-VACVARVEGSSMQPSLNPGGSQSSDVVLLNHW 64
Query: 790 SHRFGKIGLGDIVLVRSPTDPTRMVTKRILGLEGHRLSFSADPLLGDSSVSVVVPKGHVW 969
R ++ GDIV + SP +P + + KR++ LEG + +G + V VP+GH+W
Sbjct: 65 KVRNFEVQRGDIVSLVSPKNPEQKIIKRVIALEGDIVR-----TIGHKNRLVKVPRGHMW 119
Query: 970 IQGDNLYASTDSRNFGPVPYNLIEGKALLRVWPP 1071
++GD+ S DS +FGPV L+ A +WPP
Sbjct: 120 VEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPP 153
>sp|Q5PQ63|IMP2L_XENLA Mitochondrial inner membrane protease subunit 2
OS=Xenopus laevis GN=immp2l PE=2 SV=1
Length = 170
Score = 77 bits (189), Expect = 2e-013
Identities = 49/152 (32%), Positives = 76/152 (50%), Gaps = 12/152 (7%)
Frame = +1
Query: 658 SIVAKFLCLIHVTDRY---IISSTHVQGPSMLPTLNL----TGDVILAEHLSHRFGKIGL 816
+ ++ F + VT + + V+G SM P+LN D++L R +
Sbjct: 11 AFISGFFVAVPVTVTFLDRVACIARVEGVSMQPSLNPDARGESDIVLLNRWRARNYDVQR 70
Query: 817 GDIVLVRSPTDPTRMVTKRILGLEGHRLSFSADPLLGDSSVSVVVPKGHVWIQGDNLYAS 996
GDIV + SP +P + + KR++ LEG + LG + V VP+GHVW++GD+ S
Sbjct: 71 GDIVSLVSPKNPEQKIIKRVIALEGDIVK-----TLGHKNRYVKVPRGHVWVEGDHHGHS 125
Query: 997 TDSRNFGPVPYNLIEGKALLRVWPPRFFGSLR 1092
DS FGPV L+ A +WPP + L+
Sbjct: 126 FDSNAFGPVSLGLLHSHATHILWPPNRWQKLK 157
>sp|Q9UST2|IMP2L_SCHPO Mitochondrial inner membrane protease subunit 2
OS=Schizosaccharomyces pombe GN=SPBC336.13c PE=2 SV=1
Length = 180
Score = 67 bits (161), Expect = 4e-010
Identities = 33/84 (39%), Positives = 49/84 (58%), Gaps = 4/84 (4%)
Frame = +1
Query: 817 GDIVLVRSPTDPTRMVTKRILGLEGHRLSFSADPLLGDSSVSVVVPKGHVWIQGDNLYAS 996
GD+V++RSP +P ++ KR+LG+E + L V VP+GHVW++GD + S
Sbjct: 75 GDVVILRSPENPEELLVKRVLGVEYDIMKTRPPKKLS----LVPVPEGHVWVEGDEQFHS 130
Query: 997 TDSRNFGPVPYNLIEGKALLRVWP 1068
DS FGPV LI K + ++P
Sbjct: 131 IDSNKFGPVSTGLITAKVIAILFP 154
>sp|P28627|IMP1_YEAST Mitochondrial inner membrane protease subunit 1
OS=Saccharomyces cerevisiae GN=IMP1 PE=1 SV=3
Length = 190
Score = 55 bits (131), Expect = 1e-006
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
Frame = +1
Query: 658 SIVAKFLCLIHVTDRYIISSTHVQGPSMLPTLNLTGDVILAEHLSHRFGK---IGLGDIV 828
S + LC +H+ Y T +G SMLPTL+ T D + H+ F I +GD +
Sbjct: 14 SYAIRSLCFLHIIHMYAYEFTETRGESMLPTLSATNDYV---HVLKNFQNGRGIKMGDCI 70
Query: 829 LVRSPTDPTRMVTKRILGLEG 891
+ PTDP + KR+ G+ G
Sbjct: 71 VALKPTDPNHRICKRVTGMPG 91
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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