BLASTX 7.6.2
Query= UN19478 /QuerySize=1410
(1409 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2HJ41|PRP18_BOVIN Pre-mRNA-splicing factor 18 OS=Bos taurus ... 182 8e-045
sp|Q99633|PRP18_HUMAN Pre-mRNA-splicing factor 18 OS=Homo sapien... 182 8e-045
sp|Q8BM39|PRP18_MOUSE Pre-mRNA-splicing factor 18 OS=Mus musculu... 182 8e-045
sp|Q5RE03|PRP18_PONAB Pre-mRNA-splicing factor 18 OS=Pongo abeli... 182 8e-045
sp|Q9JKB8|PRP18_RAT Pre-mRNA-splicing factor 18 OS=Rattus norveg... 181 2e-044
sp|Q6GMH0|PRP18_DANRE Pre-mRNA-splicing factor 18 OS=Danio rerio... 175 1e-042
sp|Q5EAV6|PRP18_XENLA Pre-mRNA-splicing factor 18 OS=Xenopus lae... 171 1e-041
sp|O94406|PRP18_SCHPO Pre-mRNA-splicing factor 18 OS=Schizosacch... 102 6e-021
sp|P33411|PRP18_YEAST Pre-mRNA-splicing factor 18 OS=Saccharomyc... 75 1e-012
>sp|Q2HJ41|PRP18_BOVIN Pre-mRNA-splicing factor 18 OS=Bos taurus GN=PRPF18 PE=2
SV=1
Length = 342
Score = 182 bits (460), Expect = 8e-045
Identities = 95/200 (47%), Positives = 135/200 (67%), Gaps = 2/200 (1%)
Frame = -1
Query: 806 GREEGERRDDDDELSGGGGESSDVDADKDLKRLKSNFEDLCDEDKILVFYKKLLIEWKQE 627
G+E GE D ++L E++ ++ + L +D D D I F K LL W +E
Sbjct: 145 GQEPGE-EDTQNDLK-VHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKE 202
Query: 626 LDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRKKGLPSDIRQALMVMVKHCIKRDY 447
L+A E+ +R+ +GK N AT KQ YL PLF RK+ LP+DI++++ ++K ++R+Y
Sbjct: 203 LNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREY 262
Query: 446 LAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHTNSVAHIMNDETTRKYLQSVKRLM 267
+ A D Y+++AIGNAPWPIGVTMVGIH R+ REKI + VAH++NDET RKY+Q +KRLM
Sbjct: 263 VKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLM 322
Query: 266 TFCQRRYPTMPSKAVEFNSL 207
T CQ+ +PT PSK VE+N+L
Sbjct: 323 TICQKHFPTDPSKCVEYNAL 342
>sp|Q99633|PRP18_HUMAN Pre-mRNA-splicing factor 18 OS=Homo sapiens GN=PRPF18
PE=1 SV=1
Length = 342
Score = 182 bits (460), Expect = 8e-045
Identities = 95/200 (47%), Positives = 135/200 (67%), Gaps = 2/200 (1%)
Frame = -1
Query: 806 GREEGERRDDDDELSGGGGESSDVDADKDLKRLKSNFEDLCDEDKILVFYKKLLIEWKQE 627
G+E GE D ++L E++ ++ + L +D D D I F K LL W +E
Sbjct: 145 GQEPGE-EDTQNDLK-VHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKE 202
Query: 626 LDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRKKGLPSDIRQALMVMVKHCIKRDY 447
L+A E+ +R+ +GK N AT KQ YL PLF RK+ LP+DI++++ ++K ++R+Y
Sbjct: 203 LNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREY 262
Query: 446 LAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHTNSVAHIMNDETTRKYLQSVKRLM 267
+ A D Y+++AIGNAPWPIGVTMVGIH R+ REKI + VAH++NDET RKY+Q +KRLM
Sbjct: 263 VKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLM 322
Query: 266 TFCQRRYPTMPSKAVEFNSL 207
T CQ+ +PT PSK VE+N+L
Sbjct: 323 TICQKHFPTDPSKCVEYNAL 342
>sp|Q8BM39|PRP18_MOUSE Pre-mRNA-splicing factor 18 OS=Mus musculus GN=Prpf18
PE=1 SV=1
Length = 342
Score = 182 bits (460), Expect = 8e-045
Identities = 95/200 (47%), Positives = 135/200 (67%), Gaps = 2/200 (1%)
Frame = -1
Query: 806 GREEGERRDDDDELSGGGGESSDVDADKDLKRLKSNFEDLCDEDKILVFYKKLLIEWKQE 627
G+E GE D ++L E++ ++ + L +D D D I F K LL W +E
Sbjct: 145 GQEPGE-EDTQNDLK-VHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKE 202
Query: 626 LDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRKKGLPSDIRQALMVMVKHCIKRDY 447
L+A E+ +R+ +GK N AT KQ YL PLF RK+ LP+DI++++ ++K ++R+Y
Sbjct: 203 LNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREY 262
Query: 446 LAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHTNSVAHIMNDETTRKYLQSVKRLM 267
+ A D Y+++AIGNAPWPIGVTMVGIH R+ REKI + VAH++NDET RKY+Q +KRLM
Sbjct: 263 VKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLM 322
Query: 266 TFCQRRYPTMPSKAVEFNSL 207
T CQ+ +PT PSK VE+N+L
Sbjct: 323 TICQKHFPTDPSKCVEYNAL 342
>sp|Q5RE03|PRP18_PONAB Pre-mRNA-splicing factor 18 OS=Pongo abelii GN=PRPF18
PE=2 SV=1
Length = 342
Score = 182 bits (460), Expect = 8e-045
Identities = 95/200 (47%), Positives = 135/200 (67%), Gaps = 2/200 (1%)
Frame = -1
Query: 806 GREEGERRDDDDELSGGGGESSDVDADKDLKRLKSNFEDLCDEDKILVFYKKLLIEWKQE 627
G+E GE D ++L E++ ++ + L +D D D I F K LL W +E
Sbjct: 145 GQEPGE-EDTQNDLK-VHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKE 202
Query: 626 LDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRKKGLPSDIRQALMVMVKHCIKRDY 447
L+A E+ +R+ +GK N AT KQ YL PLF RK+ LP+DI++++ ++K ++R+Y
Sbjct: 203 LNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREY 262
Query: 446 LAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHTNSVAHIMNDETTRKYLQSVKRLM 267
+ A D Y+++AIGNAPWPIGVTMVGIH R+ REKI + VAH++NDET RKY+Q +KRLM
Sbjct: 263 VKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLM 322
Query: 266 TFCQRRYPTMPSKAVEFNSL 207
T CQ+ +PT PSK VE+N+L
Sbjct: 323 TICQKHFPTDPSKCVEYNAL 342
>sp|Q9JKB8|PRP18_RAT Pre-mRNA-splicing factor 18 OS=Rattus norvegicus GN=Prpf18
PE=2 SV=1
Length = 342
Score = 181 bits (457), Expect = 2e-044
Identities = 94/200 (47%), Positives = 135/200 (67%), Gaps = 2/200 (1%)
Frame = -1
Query: 806 GREEGERRDDDDELSGGGGESSDVDADKDLKRLKSNFEDLCDEDKILVFYKKLLIEWKQE 627
G+E GE D ++L E++ ++ + L +D D D I F K LL W +E
Sbjct: 145 GQEPGE-EDTQNDLK-VHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKE 202
Query: 626 LDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRKKGLPSDIRQALMVMVKHCIKRDY 447
L++ E+ +R+ +GK N AT KQ YL PLF RK+ LP+DI++++ ++K ++R+Y
Sbjct: 203 LNSREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREY 262
Query: 446 LAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHTNSVAHIMNDETTRKYLQSVKRLM 267
+ A D Y+++AIGNAPWPIGVTMVGIH R+ REKI + VAH++NDET RKY+Q +KRLM
Sbjct: 263 VKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLM 322
Query: 266 TFCQRRYPTMPSKAVEFNSL 207
T CQ+ +PT PSK VE+N+L
Sbjct: 323 TICQKHFPTDPSKCVEYNAL 342
>sp|Q6GMH0|PRP18_DANRE Pre-mRNA-splicing factor 18 OS=Danio rerio GN=prpf18 PE=2
SV=1
Length = 342
Score = 175 bits (442), Expect = 1e-042
Identities = 91/200 (45%), Positives = 131/200 (65%), Gaps = 1/200 (0%)
Frame = -1
Query: 806 GREEGERRDDDDELSGGGGESSDVDADKDLKRLKSNFEDLCDEDKILVFYKKLLIEWKQE 627
G EG D +L E++ ++ + L N D+ D D I + LL W ++
Sbjct: 144 GGAEGAELDTQHDLK-VHEENTTIEELEALGASLGNGNDVRDMDIINKVLRFLLGVWAKD 202
Query: 626 LDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRKKGLPSDIRQALMVMVKHCIKRDY 447
L++ E+ +R+ +GK AT KQ YL PLF RKK LP+DI++++ ++K ++R+Y
Sbjct: 203 LNSREDHIKRSVQGKLASATQKQTESYLEPLFRKLRKKNLPADIKESITDIIKFMLEREY 262
Query: 446 LAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHTNSVAHIMNDETTRKYLQSVKRLM 267
+ A D Y+++AIGNAPWPIGVTMVGIH R+ REKI + VAH++NDET RKY+Q +KRLM
Sbjct: 263 VKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLM 322
Query: 266 TFCQRRYPTMPSKAVEFNSL 207
T CQ+ +PT PSK VE+N+L
Sbjct: 323 TICQKHFPTDPSKCVEYNAL 342
>sp|Q5EAV6|PRP18_XENLA Pre-mRNA-splicing factor 18 OS=Xenopus laevis GN=prpf18
PE=2 SV=1
Length = 342
Score = 171 bits (433), Expect = 1e-041
Identities = 85/163 (52%), Positives = 115/163 (70%)
Frame = -1
Query: 695 EDLCDEDKILVFYKKLLIEWKQELDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRK 516
+D D D I K LL W +EL+A E+ +R+ GK AT KQ YL PLF RK
Sbjct: 180 DDNKDMDTINKVLKFLLGVWAKELNAREDYVKRSVHGKLASATQKQTESYLKPLFRKLRK 239
Query: 515 KGLPSDIRQALMVMVKHCIKRDYLAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHT 336
K LP+DI++++ ++K ++R+Y+ A D Y+++AIGNAPWPIGVTMVGIH R+ REKI +
Sbjct: 240 KNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFS 299
Query: 335 NSVAHIMNDETTRKYLQSVKRLMTFCQRRYPTMPSKAVEFNSL 207
VAH++NDET RKY+Q +KRLMT CQ+ + T PSK VE+N+L
Sbjct: 300 KHVAHVLNDETQRKYIQGLKRLMTICQKYFSTDPSKCVEYNAL 342
>sp|O94406|PRP18_SCHPO Pre-mRNA-splicing factor 18 OS=Schizosaccharomyces pombe
GN=prp18 PE=2 SV=1
Length = 343
Score = 102 bits (254), Expect = 6e-021
Identities = 51/147 (34%), Positives = 85/147 (57%)
Frame = -1
Query: 674 KILVFYKKLLIEWKQELDAVENTERRTAKGKKNVATFKQCARYLTPLFNLCRKKGLPSDI 495
+++ F + + W L + +++ + + F+Q + L L L + L DI
Sbjct: 193 QVVAFLQHGIRIWDNFLSSKSINSFESSESQMQLKIFRQAKQDLDVLIQLIVDEALNDDI 252
Query: 494 RQALMVMVKHCIKRDYLAAMDHYIKLAIGNAPWPIGVTMVGIHERSAREKIHTNSVAHIM 315
+++ + C K +++ A D Y++L IGNAPWPIGVTMVGIHERSA +++ N ++I+
Sbjct: 253 FKSIAEICYRCQKHEFVKANDMYLRLTIGNAPWPIGVTMVGIHERSAHQRLQANPSSNIL 312
Query: 314 NDETTRKYLQSVKRLMTFCQRRYPTMP 234
DE RK LQ++KR +TF +R +P
Sbjct: 313 KDEKKRKCLQALKRFITFQERESSNLP 339
>sp|P33411|PRP18_YEAST Pre-mRNA-splicing factor 18 OS=Saccharomyces cerevisiae
GN=PRP18 PE=1 SV=3
Length = 251
Score = 75 bits (183), Expect = 1e-012
Identities = 44/104 (42%), Positives = 62/104 (59%), Gaps = 2/104 (1%)
Frame = -1
Query: 566 FKQCARYLTPLFNLCRKKGLPSDIRQALMVMVKHCIK-RDYLAAMDHYIKLAIGNAPWPI 390
F + L PL R+ L D+ +L ++ H + ++ A+ Y+KL+IGN WPI
Sbjct: 136 FLDTKKALFPLLLQLRRNQLAPDLLISLATVLYHLQQPKEINLAVQSYMKLSIGNVAWPI 195
Query: 389 GVTMVGIHERSAREKIH-TNSVAHIMNDETTRKYLQSVKRLMTF 261
GVT VGIH RSA KI + A+IM DE TR ++ S+KRL+TF
Sbjct: 196 GVTSVGIHARSAHSKIQGGRNAANIMIDERTRLWITSIKRLITF 239
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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