BLASTX 7.6.2
Query= UN19580 /QuerySize=1817
(1816 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9SU63|AL2B4_ARATH Aldehyde dehydrogenase family 2 member B4,... 986 6e-287
sp|Q8S528|AL2B7_ARATH Aldehyde dehydrogenase family 2 member B7,... 839 2e-242
sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial OS=B... 611 7e-174
sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial OS=H... 611 9e-174
sp|Q5RF00|ALDH2_PONAB Aldehyde dehydrogenase, mitochondrial OS=P... 609 4e-173
sp|Q2XQV4|ALDH2_PIG Aldehyde dehydrogenase, mitochondrial OS=Sus... 606 2e-172
sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial OS=M... 605 5e-172
sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial OS=Rat... 605 5e-172
sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial OS=M... 604 7e-172
sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial OS=E... 597 1e-169
sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 OS=Gallus gallus G... 580 2e-164
sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo sapiens GN... 576 2e-163
sp|P15437|AL1A1_HORSE Retinal dehydrogenase 1 OS=Equus caballus ... 575 6e-163
sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 OS=Homo sapiens GN... 574 7e-163
sp|Q66HF8|AL1B1_RAT Aldehyde dehydrogenase X, mitochondrial OS=R... 573 2e-162
sp|P48644|AL1A1_BOVIN Retinal dehydrogenase 1 OS=Bos taurus GN=A... 572 3e-162
sp|P51977|AL1A1_SHEEP Retinal dehydrogenase 1 OS=Ovis aries GN=A... 572 3e-162
sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 OS=Mus musculus GN... 572 4e-162
sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 OS=Rattus norvegicus... 572 5e-162
sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 OS=Oryctolagus cun... 570 2e-161
>sp|Q9SU63|AL2B4_ARATH Aldehyde dehydrogenase family 2 member B4, mitochondrial
OS=Arabidopsis thaliana GN=ALDH2B4 PE=1 SV=1
Length = 538
Score = 986 bits (2549), Expect = 6e-287
Identities = 488/539 (90%), Positives = 516/539 (95%), Gaps = 3/539 (0%)
Frame = +1
Query: 58 AARRVSSLLSRSFPASSPFLFRSQGRNCCNGSSRVGRRFGTSS-AAEDIITPSVQVSYTQ 234
AARRVSSLLSRSF ASSP LFRSQGRNC NG + RRFGTSS AAE+II PSVQVS+TQ
Sbjct: 2 AARRVSSLLSRSFSASSPLLFRSQGRNCYNGG--ILRRFGTSSAAAEEIINPSVQVSHTQ 59
Query: 235 LLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINRAVKAARKAFDGGPWPKMTAY 414
LLI+GNFVD+ASGKTFPTLDPRTGEVIA+VAEGDAEDINRAVKAAR AFD GPWPKM+AY
Sbjct: 60 LLINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVKAARTAFDEGPWPKMSAY 119
Query: 415 ERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTAEIPMLARLFRYYAGWADKIHGL 594
ERSR++LRFADLVEKHSEELA+LETWDNG+ YQQ+ TAEIPM ARLFRYYAGWADKIHGL
Sbjct: 120 ERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWADKIHGL 179
Query: 595 TVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTAF 774
T+PADGNY V TLHEPIGVAGQI+PWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTAF
Sbjct: 180 TIPADGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTAF 239
Query: 775 YVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKLAFTGSTDTGKVVLGLAANSNL 954
Y GKLFLEAGLPPGVLNIVSGFG TAGA+LASHMDVDKLAFTGSTDTGKV+LGLAANSNL
Sbjct: 240 YAGKLFLEAGLPPGVLNIVSGFGATAGAALASHMDVDKLAFTGSTDTGKVILGLAANSNL 299
Query: 955 KPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQCCCAGSRTYVHEKVYDEFVEKA 1134
KPVTLELGGKSPFIVFEDADI+KAVELAHFALFFNQGQCCCAGSRT+VHEKVYDEFVEK+
Sbjct: 300 KPVTLELGGKSPFIVFEDADIDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYDEFVEKS 359
Query: 1135 KARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGVESNATLECGGDQIGNKGYFIQ 1314
KARALKRVVGDPF+KGIEQGPQID KQFEKVM+YI+SG+ESNATLECGGDQIG+KGYFIQ
Sbjct: 360 KARALKRVVGDPFRKGIEQGPQIDLKQFEKVMKYIKSGIESNATLECGGDQIGDKGYFIQ 419
Query: 1315 PTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRANETRYGLAAGVFTKSLDTANRV 1494
PTVFSNVKDDMLIAQDEIFGPVQSILKF DVDEVI+RANET+YGLAAGVFTK+LDTANRV
Sbjct: 420 PTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRANETKYGLAAGVFTKNLDTANRV 479
Query: 1495 SRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQVNAVVTPLNNPAWI 1671
SRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQ+ AVVT LN PAWI
Sbjct: 480 SRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQIKAVVTALNKPAWI 538
>sp|Q8S528|AL2B7_ARATH Aldehyde dehydrogenase family 2 member B7, mitochondrial
OS=Arabidopsis thaliana GN=ALDH2B7 PE=2 SV=2
Length = 534
Score = 839 bits (2165), Expect = 2e-242
Identities = 404/534 (75%), Positives = 471/534 (88%), Gaps = 5/534 (0%)
Frame = +1
Query: 70 VSSLLSRSFPASSPFLFRSQGRNCCNGSSRVGRRFGTSSAAEDIITPSVQVSYTQLLIDG 249
VSSLLSRSF +SS +F +G N G+ R ++A E+ ITP V+V +TQLLI G
Sbjct: 6 VSSLLSRSFMSSSRSIFSLRGMN--RGAQRYS---NLAAAVENTITPPVKVEHTQLLIGG 60
Query: 250 NFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINRAVKAARKAFDGGPWPKMTAYERSRI 429
FVDA SGKTFPTLDPR GEVIA V+EGDAED+NRAV AARKAFD GPWPKMTAYERS+I
Sbjct: 61 RFVDAVSGKTFPTLDPRNGEVIAQVSEGDAEDVNRAVAAARKAFDEGPWPKMTAYERSKI 120
Query: 430 MLRFADLVEKHSEELAALETWDNGETYQQAKTAEIPMLARLFRYYAGWADKIHGLTVPAD 609
+ RFADL+EKH++E+AALETWDNG+ Y+Q+ E+PMLAR+FRYYAGWADKIHG+T+P D
Sbjct: 121 LFRFADLIEKHNDEIAALETWDNGKPYEQSAQIEVPMLARVFRYYAGWADKIHGMTMPGD 180
Query: 610 GNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTAFYVGKL 789
G +HVQTLHEPIGVAGQI+PWNFPLLM +WK+GPALACGNT+VLKTAEQTPL+A VGKL
Sbjct: 181 GPHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGKL 240
Query: 790 FLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKLAFTGSTDTGKVVLGLAANSNLKPVTL 969
EAGLP GV+NIVSGFG TAGA++ASHMDVDK+AFTGSTD GK++L LA+ SNLK VTL
Sbjct: 241 LHEAGLPDGVVNIVSGFGATAGAAIASHMDVDKVAFTGSTDVGKIILELASKSNLKAVTL 300
Query: 970 ELGGKSPFIVFEDADINKAVELAHFALFFNQGQCCCAGSRTYVHEKVYDEFVEKAKARAL 1149
ELGGKSPFIV EDAD+++AVELAHFALFFNQGQCCCAGSRT+VHE+VYDEFVEKAKARAL
Sbjct: 301 ELGGKSPFIVCEDADVDQAVELAHFALFFNQGQCCCAGSRTFVHERVYDEFVEKAKARAL 360
Query: 1150 KRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGVESNATLECGGDQIGNKGYFIQPTVFS 1329
KR VGDPFK GIEQGPQ+DS+QF K+++YI+ GVE+ ATL+ GGD++G+KGY+IQPTVFS
Sbjct: 361 KRNVGDPFKSGIEQGPQVDSEQFNKILKYIKHGVEAGATLQAGGDRLGSKGYYIQPTVFS 420
Query: 1330 NVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRANETRYGLAAGVFTKSLDTANRVSRALK 1509
+VKDDMLIA DEIFGPVQ+ILKF+D+DEVI RAN +RYGLAAGVFT++LDTA+R+ RAL+
Sbjct: 421 DVKDDMLIATDEIFGPVQTILKFKDLDEVIARANNSRYGLAAGVFTQNLDTAHRLMRALR 480
Query: 1510 AGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQVNAVVTPLNNPAWI 1671
GTVW+NCFDV DA+IPFGGYKMSG GREKGIYSLNNYLQV AVVT L NPAW+
Sbjct: 481 VGTVWINCFDVLDASIPFGGYKMSGIGREKGIYSLNNYLQVKAVVTSLKNPAWL 534
>sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial OS=Bos taurus
GN=ALDH2 PE=1 SV=2
Length = 520
Score = 611 bits (1574), Expect = 7e-174
Identities = 302/498 (60%), Positives = 373/498 (74%), Gaps = 4/498 (0%)
Frame = +1
Query: 157 RVGRRFGTSSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAE 330
R GRR S+A + + TP+ Q V Y Q+ I+ + DA S KTFPT++P TG+VI +VAE
Sbjct: 15 RQGRRL-LSAATQAVPTPNQQPEVLYNQIFINNEWHDAVSKKTFPTVNPSTGDVICHVAE 73
Query: 331 GDAEDINRAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGET 507
GD D++RAVKAAR AF G PW +M A ER R++ R ADL+E+ LAALET DNG+
Sbjct: 74 GDKADVDRAVKAARAAFQLGSPWRRMDASERGRLLNRLADLIERDRTYLAALETLDNGKP 133
Query: 508 YQQAKTAEIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLL 687
Y + ++ M+ + RYYAGWADK HG T+P DG+Y T HEP+GV GQI+PWNFPLL
Sbjct: 134 YIISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDYFSYTRHEPVGVCGQIIPWNFPLL 193
Query: 688 MFAWKVGPALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLA 867
M AWK+GPALA GN +V+K AEQTPLTA YV L EAG PPGV+N++ GFGPTAGA++A
Sbjct: 194 MQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIA 253
Query: 868 SHMDVDKLAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFA 1047
SH DVDK+AFTGST+ G ++ A SNLK VTLELGGKSP I+ DAD++ AVE AHFA
Sbjct: 254 SHEDVDKVAFTGSTEVGHLIQVAAGKSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFA 313
Query: 1048 LFFNQGQCCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKV 1227
LFFNQGQCCCAGSRT+V E +Y EFVE++ ARA RVVG+PF EQGPQ+D QF+KV
Sbjct: 314 LFFNQGQCCCAGSRTFVQEDIYAEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKV 373
Query: 1228 MRYIRSGVESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDV 1407
+ YI+SG E A L CGG ++GYFIQPTVF +V+D M IA++EIFGPV ILKF+ +
Sbjct: 374 LGYIKSGKEEGAKLLCGGGAAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKSM 433
Query: 1408 DEVIRRANETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGN 1587
+EV+ RAN ++YGLAA VFTK LD AN +S+AL+AGTVWVNC+DVF A PFGGYK+SG+
Sbjct: 434 EEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGS 493
Query: 1588 GREKGIYSLNNYLQVNAV 1641
GRE G Y L Y +V V
Sbjct: 494 GRELGEYGLQAYTEVKTV 511
>sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens
GN=ALDH2 PE=1 SV=2
Length = 517
Score = 611 bits (1573), Expect = 9e-174
Identities = 300/498 (60%), Positives = 373/498 (74%), Gaps = 3/498 (0%)
Frame = +1
Query: 157 RVGRRFGTSSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAE 330
R+GRR +++A + + P+ Q V Q+ I+ + DA S KTFPT++P TGEVI VAE
Sbjct: 11 RLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAE 70
Query: 331 GDAEDINRAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGET 507
GD ED+++AVKAAR AF G PW +M A R R++ R ADL+E+ LAALET DNG+
Sbjct: 71 GDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKP 130
Query: 508 YQQAKTAEIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLL 687
Y + ++ M+ + RYYAGWADK HG T+P DG++ T HEP+GV GQI+PWNFPLL
Sbjct: 131 YVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLL 190
Query: 688 MFAWKVGPALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLA 867
M AWK+GPALA GN +V+K AEQTPLTA YV L EAG PPGV+NIV GFGPTAGA++A
Sbjct: 191 MQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIA 250
Query: 868 SHMDVDKLAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFA 1047
SH DVDK+AFTGST+ G+V+ A +SNLK VTLELGGKSP I+ DAD++ AVE AHFA
Sbjct: 251 SHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFA 310
Query: 1048 LFFNQGQCCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKV 1227
LFFNQGQCCCAGSRT+V E +YDEFVE++ ARA RVVG+PF EQGPQ+D QF+K+
Sbjct: 311 LFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKI 370
Query: 1228 MRYIRSGVESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDV 1407
+ YI +G + A L CGG ++GYFIQPTVF +V+D M IA++EIFGPV ILKF+ +
Sbjct: 371 LGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTI 430
Query: 1408 DEVIRRANETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGN 1587
+EV+ RAN + YGLAA VFTK LD AN +S+AL+AGTVWVNC+DVF A PFGGYKMSG+
Sbjct: 431 EEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGS 490
Query: 1588 GREKGIYSLNNYLQVNAV 1641
GRE G Y L Y +V V
Sbjct: 491 GRELGEYGLQAYTEVKTV 508
>sp|Q5RF00|ALDH2_PONAB Aldehyde dehydrogenase, mitochondrial OS=Pongo abelii
GN=ALDH2 PE=2 SV=1
Length = 517
Score = 609 bits (1568), Expect = 4e-173
Identities = 299/498 (60%), Positives = 373/498 (74%), Gaps = 3/498 (0%)
Frame = +1
Query: 157 RVGRRFGTSSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAE 330
R+GRR +++A + + P+ Q V Q+ I+ + DA S KTFPT++P TGEVI VAE
Sbjct: 11 RLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAE 70
Query: 331 GDAEDINRAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGET 507
GD ED+++AVKAAR AF G PW +M A R R++ R ADL+E+ LAALET DNG+
Sbjct: 71 GDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKP 130
Query: 508 YQQAKTAEIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLL 687
Y + ++ M+ + RYYAGWADK HG T+P DG++ T HEP+GV GQI+PWNFPLL
Sbjct: 131 YVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLL 190
Query: 688 MFAWKVGPALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLA 867
M AWK+GPALA GN +V+K AEQTPLTA YV L EAG PPGV+NIV GFGPTAGA++A
Sbjct: 191 MQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIA 250
Query: 868 SHMDVDKLAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFA 1047
SH DVDK+AFTGST+ G+V+ A +SNLK VTLELGGKSP I+ DAD++ AVE AHFA
Sbjct: 251 SHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFA 310
Query: 1048 LFFNQGQCCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKV 1227
LFFNQGQCCCAGSRT+V E +YDEFVE++ ARA RVVG+PF EQGPQ+D QF+K+
Sbjct: 311 LFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKI 370
Query: 1228 MRYIRSGVESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDV 1407
+ YI +G + A L CGG ++GYFIQPTVF +V+D M IA++EIFGPV ILKF+ +
Sbjct: 371 LGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTI 430
Query: 1408 DEVIRRANETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGN 1587
+EV+ RAN + YGLAA VFTK LD AN +S+AL+AGTVWVNC++VF A PFGGYKMSG+
Sbjct: 431 EEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYNVFGAQSPFGGYKMSGS 490
Query: 1588 GREKGIYSLNNYLQVNAV 1641
GRE G Y L Y +V V
Sbjct: 491 GRELGEYGLQAYTEVKTV 508
>sp|Q2XQV4|ALDH2_PIG Aldehyde dehydrogenase, mitochondrial OS=Sus scrofa
GN=ALDH2 PE=2 SV=1
Length = 521
Score = 606 bits (1562), Expect = 2e-172
Identities = 297/498 (59%), Positives = 373/498 (74%), Gaps = 3/498 (0%)
Frame = +1
Query: 157 RVGRRFGTSSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAE 330
R GRR +++ + + P+ Q + Y Q+ I+ + DA S KTFPT++P TG+VI +VAE
Sbjct: 15 RQGRRLLSAAPTQAVPAPNQQPEIFYNQIFINNEWHDAISKKTFPTVNPSTGDVICHVAE 74
Query: 331 GDAEDINRAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGET 507
GD ED++RAV+AAR AF G PW ++ A +R R++ R ADL+E+ LAALET DNG+
Sbjct: 75 GDKEDVDRAVEAARAAFQLGSPWRRLDASDRGRLLNRLADLIERDRTYLAALETLDNGKP 134
Query: 508 YQQAKTAEIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLL 687
Y + ++ M+ + RYYAGWADK HG T+P DG+Y T HEP+GV GQI+PWNFPLL
Sbjct: 135 YVISYLVDLDMVLKCLRYYAGWADKYHGKTLPIDGDYFSYTRHEPVGVCGQIIPWNFPLL 194
Query: 688 MFAWKVGPALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLA 867
M AWK+GPALA GN +V+K +EQTPLTA YV L EAG PPGV+NIV G+GPTAGA++A
Sbjct: 195 MQAWKLGPALATGNVVVMKVSEQTPLTALYVANLIKEAGFPPGVVNIVPGYGPTAGAAIA 254
Query: 868 SHMDVDKLAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFA 1047
SH DVDK+AFTGST+ G ++ A SNLK VTLELGGKSP I+ DAD++ AVE AHFA
Sbjct: 255 SHEDVDKVAFTGSTEVGHLIQVAAGKSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFA 314
Query: 1048 LFFNQGQCCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKV 1227
LFFNQGQCCCAGSRT+V E +Y EFVE++ ARA RVVG+PF EQGPQID QF+K+
Sbjct: 315 LFFNQGQCCCAGSRTFVQEDIYAEFVERSVARARSRVVGNPFDSRTEQGPQIDETQFKKI 374
Query: 1228 MRYIRSGVESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDV 1407
+ YI+SG E A L CGG ++GYFIQPTVF +V+D M IA++EIFGPV ILKF+ +
Sbjct: 375 LGYIKSGKEEGAKLLCGGGAAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTI 434
Query: 1408 DEVIRRANETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGN 1587
+EVI RAN ++YGLAA VFTK LD AN +S+AL+AGTVWVNC+DVF A PFGGYK+SG+
Sbjct: 435 EEVIGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGS 494
Query: 1588 GREKGIYSLNNYLQVNAV 1641
GRE G Y L Y +V V
Sbjct: 495 GRELGEYGLQAYTEVKTV 512
>sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial OS=Mesocricetus
auratus GN=ALDH2 PE=1 SV=1
Length = 500
Score = 605 bits (1558), Expect = 5e-172
Identities = 296/491 (60%), Positives = 368/491 (74%), Gaps = 3/491 (0%)
Frame = +1
Query: 178 TSSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDIN 351
+++A + P+ Q V Q+ I+ + DA S KTFPT++P TGEVI VAEG ED++
Sbjct: 1 SAAATSAVPAPNQQPEVFCNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGSKEDVD 60
Query: 352 RAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTA 528
+AVKAAR AF G PW +M A +R R++ R ADL+E+ LAALET DNG+ Y +
Sbjct: 61 KAVKAARAAFQLGSPWRRMDASDRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLV 120
Query: 529 EIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVG 708
++ M+ + RYYAGWADK HG T+P DG++ T HEP+GV GQI+PWNFPLLM AWK+G
Sbjct: 121 DLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLG 180
Query: 709 PALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDK 888
PALA GN +V+K AEQTPLTA YV L EAG PPGV+NIV GFGPTAGA++ASH DVDK
Sbjct: 181 PALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDK 240
Query: 889 LAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQ 1068
+AFTGST+ G ++ A +SNLK VTLELGGKSP I+ DAD++ AVE AHFALFFNQGQ
Sbjct: 241 VAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQ 300
Query: 1069 CCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSG 1248
CCCAGSRT+V E VYDEFVE++ ARA RVVG+PF EQGPQ+D QF+K++ YI+SG
Sbjct: 301 CCCAGSRTFVQEDVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYIKSG 360
Query: 1249 VESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRA 1428
+ A L CGG ++GYFIQPTVF +VKD M IA++EIFGPV ILKF+ ++EV+ RA
Sbjct: 361 QQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRA 420
Query: 1429 NETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIY 1608
N ++YGLAA VFTK LD AN +S+AL+AGTVW+NC+DVF A PFGGYKMSG+GRE G Y
Sbjct: 421 NNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEY 480
Query: 1609 SLNNYLQVNAV 1641
L Y +V V
Sbjct: 481 GLQAYTEVKTV 491
>sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial OS=Rattus norvegicus
GN=Aldh2 PE=1 SV=1
Length = 519
Score = 605 bits (1558), Expect = 5e-172
Identities = 296/494 (59%), Positives = 370/494 (74%), Gaps = 3/494 (0%)
Frame = +1
Query: 169 RFGTSSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAE 342
R +++A + P+ Q V Q+ I+ + DA S KTFPT++P TGEVI VAEG+ E
Sbjct: 17 RLLSAAATSAVPAPNQQPEVFCNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGNKE 76
Query: 343 DINRAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQA 519
D+++AVKAA+ AF G PW +M A +R R++ R ADL+E+ LAALET DNG+ Y +
Sbjct: 77 DVDKAVKAAQAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVIS 136
Query: 520 KTAEIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAW 699
++ M+ + RYYAGWADK HG T+P DG++ T HEP+GV GQI+PWNFPLLM AW
Sbjct: 137 YLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAW 196
Query: 700 KVGPALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMD 879
K+GPALA GN +V+K AEQTPLTA YV L EAG PPGV+NIV GFGPTAGA++ASH D
Sbjct: 197 KLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHED 256
Query: 880 VDKLAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFN 1059
VDK+AFTGST+ G ++ A +SNLK VTLELGGKSP I+ DAD++ AVE AHFALFFN
Sbjct: 257 VDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFN 316
Query: 1060 QGQCCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYI 1239
QGQCCCAGSRT+V E VYDEFVE++ ARA RVVG+PF EQGPQ+D QF+K++ YI
Sbjct: 317 QGQCCCAGSRTFVQEDVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYI 376
Query: 1240 RSGVESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVI 1419
+SG + A L CGG ++GYFIQPTVF +VKD M IA++EIFGPV ILKF+ ++EV+
Sbjct: 377 KSGQQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVV 436
Query: 1420 RRANETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREK 1599
RAN ++YGLAA VFTK LD AN +S+AL+AGTVW+NC+DVF A PFGGYKMSG+GRE
Sbjct: 437 GRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGREL 496
Query: 1600 GIYSLNNYLQVNAV 1641
G Y L Y +V V
Sbjct: 497 GEYGLQAYTEVKTV 510
>sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial OS=Mus musculus
GN=Aldh2 PE=1 SV=1
Length = 519
Score = 604 bits (1557), Expect = 7e-172
Identities = 296/494 (59%), Positives = 370/494 (74%), Gaps = 3/494 (0%)
Frame = +1
Query: 169 RFGTSSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAE 342
R +++A + P+ Q V Q+ I+ + DA S KTFPT++P TGEVI VAEG+ E
Sbjct: 17 RLLSAAATSAVPAPNHQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGNKE 76
Query: 343 DINRAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQA 519
D+++AVKAAR AF G PW +M A +R R++ R ADL+E+ LAALET DNG+ Y +
Sbjct: 77 DVDKAVKAARAAFQLGSPWRRMDASDRGRLLYRLADLIERDRTYLAALETLDNGKPYVIS 136
Query: 520 KTAEIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAW 699
++ M+ + RYYAGWADK HG T+P DG++ T HEP+GV GQI+PWNFPLLM AW
Sbjct: 137 YLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAW 196
Query: 700 KVGPALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMD 879
K+GPALA GN +V+K AEQTPLTA YV L EAG PPGV+NIV GFGPTAGA++ASH
Sbjct: 197 KLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEG 256
Query: 880 VDKLAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFN 1059
VDK+AFTGST+ G ++ A +SNLK VTLELGGKSP I+ DAD++ AVE AHFALFFN
Sbjct: 257 VDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFN 316
Query: 1060 QGQCCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYI 1239
QGQCCCAGSRT+V E VYDEFVE++ ARA RVVG+PF EQGPQ+D QF+K++ YI
Sbjct: 317 QGQCCCAGSRTFVQENVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYI 376
Query: 1240 RSGVESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVI 1419
+SG + A L CGG ++GYFIQPTVF +VKD M IA++EIFGPV ILKF+ ++EV+
Sbjct: 377 KSGQQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVV 436
Query: 1420 RRANETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREK 1599
RAN+++YGLAA VFTK LD AN +S+AL+AGTVW+NC+DVF A PFGGYKMSG+GRE
Sbjct: 437 GRANDSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGREL 496
Query: 1600 GIYSLNNYLQVNAV 1641
G Y L Y +V V
Sbjct: 497 GEYGLQAYTEVKTV 510
>sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial OS=Equus caballus
GN=ALDH2 PE=1 SV=1
Length = 500
Score = 597 bits (1537), Expect = 1e-169
Identities = 296/490 (60%), Positives = 364/490 (74%), Gaps = 3/490 (0%)
Frame = +1
Query: 181 SSAAEDIITPSVQ--VSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINR 354
++A + + P+ Q V Y Q+ I+ + DA S KTFPT++P TGEVI VA GD ED++R
Sbjct: 2 AAATQAVPAPNQQPEVFYNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAAGDKEDVDR 61
Query: 355 AVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTAE 531
AVKAAR AF G PW +M A +R R++ R ADL+E+ LAALET DNG+ Y + +
Sbjct: 62 AVKAARAAFQLGSPWRRMDASDRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVD 121
Query: 532 IPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGP 711
+ M+ + RYYAGWADK HG T+P DG++ T HEP+GV GQI+PWNFPLLM A K+GP
Sbjct: 122 LDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAAKLGP 181
Query: 712 ALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKL 891
ALA GN +V+K AEQTPLTA YV L EAG PPGV+N+V GFGPTAGA++ASH DVDK+
Sbjct: 182 ALATGNVVVMKVAEQTPLTALYVANLTKEAGFPPGVVNVVPGFGPTAGAAIASHEDVDKV 241
Query: 892 AFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQC 1071
AFTGST+ G ++ A SNLK VTLELGGKSP I+ DAD++ AVE AHFALFFNQGQC
Sbjct: 242 AFTGSTEVGHLIQVAAGRSNLKKVTLELGGKSPNIIVSDADMDWAVEQAHFALFFNQGQC 301
Query: 1072 CCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGV 1251
C AGSRT+V E VY EFVE++ ARA RVVG+PF EQGPQ+D QF KV+ YI+SG
Sbjct: 302 CGAGSRTFVQEDVYAEFVERSVARAKSRVVGNPFDSQTEQGPQVDETQFNKVLGYIKSGK 361
Query: 1252 ESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRAN 1431
E A L CGG ++GYFIQPTVF +V+D M IA++EIFGPV ILKF+ ++EV+ RAN
Sbjct: 362 EEGAKLLCGGGAAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRAN 421
Query: 1432 ETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYS 1611
++YGLAA VFTK LD AN +S+AL+AGTVW+NC+DVF A PFGGYKMSGNGRE G Y
Sbjct: 422 NSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGNGRELGEYG 481
Query: 1612 LNNYLQVNAV 1641
L Y +V V
Sbjct: 482 LQAYTEVKTV 491
>sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 OS=Gallus gallus GN=ALDH1A1 PE=2
SV=1
Length = 509
Score = 580 bits (1493), Expect = 2e-164
Identities = 276/477 (57%), Positives = 348/477 (72%), Gaps = 1/477 (0%)
Frame = +1
Query: 214 VQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINRAVKAARKAFD-GG 390
+++ YT++ I+ + D+ SGK F +P E I VAEGD DI++AVKAARKAF+ G
Sbjct: 24 LKIKYTKIFINNEWHDSVSGKKFEVFNPANEEKICEVAEGDKADIDKAVKAARKAFELGS 83
Query: 391 PWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTAEIPMLARLFRYYAG 570
PW M A ER R++ + ADLVE+ LA +E D G+ + A ++ + RY AG
Sbjct: 84 PWRTMDASERGRLLNKLADLVERDRLTLATMEAIDGGKLFSTAYLMDLGACIKTIRYCAG 143
Query: 571 WADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGPALACGNTIVLKTA 750
WADKIHG TVP DGN+ T HEP+GV GQI+PWNFPL+MF WK+ PAL CGNT+V+K A
Sbjct: 144 WADKIHGRTVPMDGNFFTFTRHEPVGVCGQIIPWNFPLVMFIWKIAPALCCGNTVVVKPA 203
Query: 751 EQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKLAFTGSTDTGKVVL 930
EQTPL+A Y+G L EAG PPGV+NIV GFGPTAGA+++ HMD+DK++FTGST+ GK++
Sbjct: 204 EQTPLSALYMGSLIKEAGFPPGVVNIVPGFGPTAGAAISHHMDIDKVSFTGSTEVGKLIK 263
Query: 931 GLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQCCCAGSRTYVHEKV 1110
A +NLK VTLELGGKSP I+F DAD+++A E AH LF++QGQCC AGSR +V E +
Sbjct: 264 EAAGKTNLKRVTLELGGKSPNIIFADADLDEAAEFAHIGLFYHQGQCCIAGSRIFVEEPI 323
Query: 1111 YDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGVESNATLECGGDQI 1290
YDEFV ++ RA K +GDP G++QGPQID +QF+K++ I SG + A LECGG
Sbjct: 324 YDEFVRRSIERAKKYTLGDPLLPGVQQGPQIDKEQFQKILDLIESGKKEGAKLECGGGPW 383
Query: 1291 GNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRANETRYGLAAGVFTK 1470
GNKGYFIQPTVFSNV DDM IA++EIFGPVQ I+KF+ +DEVI+RAN T YGLAA VFTK
Sbjct: 384 GNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKTIDEVIKRANNTTYGLAAAVFTK 443
Query: 1471 SLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQVNAV 1641
+D A + AL+AGTVWVNC+ F A PFGG+KMSGNGRE G Y L Y +V V
Sbjct: 444 DIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMSGNGRELGEYGLQEYTEVKTV 500
>sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo sapiens GN=ALDH1A2 PE=1
SV=3
Length = 518
Score = 576 bits (1484), Expect = 2e-163
Identities = 271/484 (55%), Positives = 357/484 (73%), Gaps = 1/484 (0%)
Frame = +1
Query: 205 TPSVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINRAVKAARKAFD 384
TP++++ YT++ I+ + ++ SG+ FP +P TGE + V E D DI++AV+AAR AF
Sbjct: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFS 89
Query: 385 -GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTAEIPMLARLFRY 561
G W +M A ER R++ + ADLVE+ LA +E+ + G+ + QA ++ + + FRY
Sbjct: 90 LGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRY 149
Query: 562 YAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGPALACGNTIVL 741
YAGWADKIHG+T+P DG+Y T HEPIGV GQI+PWNFPLLMFAWK+ PAL CGNT+V+
Sbjct: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVI 209
Query: 742 KTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKLAFTGSTDTGK 921
K AEQTPL+A Y+G L EAG PPGV+NI+ G+GPTAGA++ASH+ +DK+AFTGST+ GK
Sbjct: 210 KPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269
Query: 922 VVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQCCCAGSRTYVH 1101
++ A SNLK VTLELGGKSP I+F DAD++ AVE AH +FFNQGQCC AGSR +V
Sbjct: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329
Query: 1102 EKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGVESNATLECGG 1281
E +Y+EFV ++ RA +RVVG PF EQGPQID KQ+ K++ I+SGV A LECGG
Sbjct: 330 ESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389
Query: 1282 DQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRANETRYGLAAGV 1461
+G KG+FI+PTVFSNV DDM IA++EIFGPVQ IL+F+ +DEVI RAN + +GL A V
Sbjct: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449
Query: 1462 FTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQVNAV 1641
FT ++ A VS A++AGTVW+NC++ +A PFGG+KMSGNGRE G + L Y +V V
Sbjct: 450 FTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509
Query: 1642 VTPL 1653
+
Sbjct: 510 TVKI 513
>sp|P15437|AL1A1_HORSE Retinal dehydrogenase 1 OS=Equus caballus GN=ALDH1A1 PE=1
SV=1
Length = 500
Score = 575 bits (1480), Expect = 6e-163
Identities = 276/496 (55%), Positives = 357/496 (71%), Gaps = 3/496 (0%)
Frame = +1
Query: 178 TSSAAED--IITPSVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDIN 351
+SS D ++ ++ YT++ I+ + D+ SGK FP +P T E + V EGD ED+N
Sbjct: 1 SSSGTPDLPVLLTDLKFQYTKIFINNEWHDSVSGKKFPVFNPATEEKLCEVEEGDKEDVN 60
Query: 352 RAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTA 528
+AV AAR+AF G PW M A ER R++ + ADLVE+ LA +E+ + G+ + A
Sbjct: 61 KAVAAARQAFQIGSPWRTMDASERGRLLYKLADLVERDRLILATMESMNGGKLFSNAYLM 120
Query: 529 EIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVG 708
++ + RY AGWADKI G T+P+DGN+ T HEP+GV GQI+PWNFPLLMF WK+
Sbjct: 121 DLGGCLKTLRYCAGWADKIQGRTIPSDGNFFTYTRHEPVGVCGQILPWNFPLLMFLWKIA 180
Query: 709 PALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDK 888
PAL+CGNT+V+K AEQTPL+A +V L EAG PPGV+NIV G+GPTAGA+++SHMD+DK
Sbjct: 181 PALSCGNTVVVKPAEQTPLSALHVATLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDK 240
Query: 889 LAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQ 1068
+AFTGST+ GK++ A SNLK VTLELGGKSPFIVF DAD+ A+E+ H ALF++QGQ
Sbjct: 241 VAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPFIVFADADLETALEVTHQALFYHQGQ 300
Query: 1069 CCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSG 1248
CC A SR +V E +YDEFV ++ RA K V+G+P G+ QGPQID +Q++K++ I SG
Sbjct: 301 CCVAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYDKILDLIESG 360
Query: 1249 VESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRA 1428
+ A LECGG GNKGYFIQPTVFSNV D+M IA++EIFGPVQ I+KF+ +D+VI+RA
Sbjct: 361 KKEGAKLECGGGPWGNKGYFIQPTVFSNVSDEMRIAKEEIFGPVQQIMKFKSLDDVIKRA 420
Query: 1429 NETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIY 1608
N T YGL AG FTK LD A VS AL+AGTVWVNC+ V A PFGG+KMSGNGRE G Y
Sbjct: 421 NNTTYGLFAGSFTKDLDKAITVSAALQAGTVWVNCYGVVSAQCPFGGFKMSGNGREMGEY 480
Query: 1609 SLNNYLQVNAVVTPLN 1656
+ Y +V V ++
Sbjct: 481 GFHEYTEVKTVTVKIS 496
>sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 OS=Homo sapiens GN=ALDH1A1 PE=1
SV=2
Length = 501
Score = 574 bits (1479), Expect = 7e-163
Identities = 272/496 (54%), Positives = 358/496 (72%), Gaps = 3/496 (0%)
Frame = +1
Query: 178 TSSAAED--IITPSVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDIN 351
+SS D ++ +++ YT++ I+ + D+ SGK FP +P T E + V EGD ED++
Sbjct: 2 SSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVD 61
Query: 352 RAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTA 528
+AVKAAR+AF G PW M A ER R++ + ADL+E+ LA +E+ + G+ Y A
Sbjct: 62 KAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLN 121
Query: 529 EIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVG 708
++ + RY AGWADKI G T+P DGN+ T HEPIGV GQI+PWNFPL+M WK+G
Sbjct: 122 DLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIG 181
Query: 709 PALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDK 888
PAL+CGNT+V+K AEQTPLTA +V L EAG PPGV+NIV G+GPTAGA+++SHMD+DK
Sbjct: 182 PALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDK 241
Query: 889 LAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQ 1068
+AFTGST+ GK++ A SNLK VTLELGGKSP IV DAD++ AVE AH +F++QGQ
Sbjct: 242 VAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQ 301
Query: 1069 CCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSG 1248
CC A SR +V E +YDEFV ++ RA K ++G+P G+ QGPQID +Q++K++ I SG
Sbjct: 302 CCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESG 361
Query: 1249 VESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRA 1428
+ A LECGG GNKGYF+QPTVFSNV D+M IA++EIFGPVQ I+KF+ +D+VI+RA
Sbjct: 362 KKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRA 421
Query: 1429 NETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIY 1608
N T YGL+AGVFTK +D A +S AL+AGTVWVNC+ V A PFGG+KMSGNGRE G Y
Sbjct: 422 NNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEY 481
Query: 1609 SLNNYLQVNAVVTPLN 1656
+ Y +V V ++
Sbjct: 482 GFHEYTEVKTVTVKIS 497
>sp|Q66HF8|AL1B1_RAT Aldehyde dehydrogenase X, mitochondrial OS=Rattus
norvegicus GN=Aldh1b1 PE=1 SV=1
Length = 519
Score = 573 bits (1475), Expect = 2e-162
Identities = 276/491 (56%), Positives = 365/491 (74%), Gaps = 2/491 (0%)
Frame = +1
Query: 172 FGTSSAAEDIITPSVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDIN 351
+ T++A + I P+ ++ Y QL I+ + DA S KTFPT++P TGEVI +VAEGD D++
Sbjct: 21 YSTAAALPNPI-PNPEIRYNQLFINNEWHDAVSKKTFPTVNPTTGEVIGHVAEGDRADVD 79
Query: 352 RAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTA 528
AV+AAR+AF G PW +M A ER R++ R ADLVE+ LA+LET DNG+ +Q++
Sbjct: 80 LAVRAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYVL 139
Query: 529 EIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVG 708
++ + +++RY AGWADK HG T+P DG + T HEP+GV GQI+PWNFPL+M WK+
Sbjct: 140 DLDEVIKVYRYLAGWADKWHGKTIPMDGEHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLA 199
Query: 709 PALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDK 888
PALA GNT+V+K AEQTPL+A Y+ L EAG PPGV+NI++G+GPTAGA++A HMDVDK
Sbjct: 200 PALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDK 259
Query: 889 LAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQ 1068
+AFTGST+ G ++ A +SNLK VTLELGGKSP IV DAD++ AV+ H ALFFN GQ
Sbjct: 260 VAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMDHAVDQCHEALFFNMGQ 319
Query: 1069 CCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSG 1248
CCCAGSRT+V E +Y EF+E+ +A KR VG+PF+ +QGPQ+D +QFEK++ YIR G
Sbjct: 320 CCCAGSRTFVEESIYHEFLERTVEKAKKRKVGNPFELDTQQGPQVDKEQFEKILGYIRLG 379
Query: 1249 VESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRA 1428
+ A L CGG++ G +G+FI+PTVF NV+DDM IA++EIFGPVQ + KF+ ++EVI+RA
Sbjct: 380 QKEGAKLLCGGERFGERGFFIKPTVFGNVQDDMRIAREEIFGPVQPLFKFKKIEEVIQRA 439
Query: 1429 NETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIY 1608
N TRYGLAA VFT+ LD A S+AL+AGTVWVN +++ PFGG+K SGNGRE G
Sbjct: 440 NNTRYGLAAAVFTRDLDKALYFSQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGED 499
Query: 1609 SLNNYLQVNAV 1641
L Y +V V
Sbjct: 500 GLKAYTEVKTV 510
>sp|P48644|AL1A1_BOVIN Retinal dehydrogenase 1 OS=Bos taurus GN=ALDH1A1 PE=2
SV=3
Length = 501
Score = 572 bits (1474), Expect = 3e-162
Identities = 275/496 (55%), Positives = 358/496 (72%), Gaps = 3/496 (0%)
Frame = +1
Query: 178 TSSAAEDIITP--SVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDIN 351
+SSA D+ P ++Q YT++ I+ + + SGK FP +P T E + V EGD ED++
Sbjct: 2 SSSAMPDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVD 61
Query: 352 RAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTA 528
+AVKAAR+AF G PW M A ER R++ + ADL+E+ LA +E + G+ + A
Sbjct: 62 KAVKAARQAFQIGSPWRTMDASERGRLLNKLADLIERDHLLLATMEAMNGGKLFSNAYLM 121
Query: 529 EIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVG 708
++ + RY AGWADKI G T+P DGN+ T EP+GV GQI+PWNFPLLMF WK+G
Sbjct: 122 DLGGCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIG 181
Query: 709 PALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDK 888
PAL+CGNT+V+K AEQTPLTA ++G L EAG PPGV+NIV G+GPTAGA+++SHMDVDK
Sbjct: 182 PALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDK 241
Query: 889 LAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQ 1068
+AFTGST+ GK++ A SNLK V+LELGGKSP IVF DAD++ AVE AH +F++QGQ
Sbjct: 242 VAFTGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQ 301
Query: 1069 CCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSG 1248
CC A SR +V E +YDEFV ++ RA K V+G+P G+ QGPQID +Q+EK++ I SG
Sbjct: 302 CCIAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESG 361
Query: 1249 VESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRA 1428
+ A LECGG GNKGYFIQPTVFS+V DDM IA++EIFGPVQ I+KF+ +D+VI+RA
Sbjct: 362 KKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRA 421
Query: 1429 NETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIY 1608
N T YGL+AG+FT +D A VS AL++GTVWVNC+ V A PFGG+KMSGNGRE G Y
Sbjct: 422 NNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEY 481
Query: 1609 SLNNYLQVNAVVTPLN 1656
+ Y +V V ++
Sbjct: 482 GFHEYTEVKTVTIKIS 497
>sp|P51977|AL1A1_SHEEP Retinal dehydrogenase 1 OS=Ovis aries GN=ALDH1A1 PE=1
SV=2
Length = 501
Score = 572 bits (1474), Expect = 3e-162
Identities = 275/496 (55%), Positives = 358/496 (72%), Gaps = 3/496 (0%)
Frame = +1
Query: 178 TSSAAEDIITP--SVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDIN 351
+SSA D+ P ++Q YT++ I+ + + SGK FP +P T E + V EGD ED++
Sbjct: 2 SSSAMPDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVD 61
Query: 352 RAVKAARKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTA 528
+AVKAAR+AF G PW M A ER R++ + ADL+E+ LA +E + G+ + A
Sbjct: 62 KAVKAARQAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLM 121
Query: 529 EIPMLARLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVG 708
++ + RY AGWADKI G T+P DGN+ T EP+GV GQI+PWNFPLLMF WK+G
Sbjct: 122 DLGGCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIG 181
Query: 709 PALACGNTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDK 888
PAL+CGNT+V+K AEQTPLTA ++G L EAG PPGV+NIV G+GPTAGA+++SHMDVDK
Sbjct: 182 PALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDK 241
Query: 889 LAFTGSTDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQ 1068
+AFTGST+ GK++ A SNLK V+LELGGKSP IVF DAD++ AVE AH +F++QGQ
Sbjct: 242 VAFTGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQ 301
Query: 1069 CCCAGSRTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSG 1248
CC A SR +V E +YDEFV ++ RA K V+G+P G+ QGPQID +Q+EK++ I SG
Sbjct: 302 CCIAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESG 361
Query: 1249 VESNATLECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRA 1428
+ A LECGG GNKGYFIQPTVFS+V DDM IA++EIFGPVQ I+KF+ +D+VI+RA
Sbjct: 362 KKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRA 421
Query: 1429 NETRYGLAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIY 1608
N T YGL+AG+FT +D A VS AL++GTVWVNC+ V A PFGG+KMSGNGRE G Y
Sbjct: 422 NNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEY 481
Query: 1609 SLNNYLQVNAVVTPLN 1656
+ Y +V V ++
Sbjct: 482 GFHEYTEVKTVTIKIS 497
>sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 OS=Mus musculus GN=Aldh1a2 PE=1
SV=2
Length = 518
Score = 572 bits (1473), Expect = 4e-162
Identities = 269/484 (55%), Positives = 356/484 (73%), Gaps = 1/484 (0%)
Frame = +1
Query: 205 TPSVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINRAVKAARKAFD 384
TP++++ YT++ I+ + ++ SG+ FP +P TGE + V E D DI++AV+AAR AF
Sbjct: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFS 89
Query: 385 -GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTAEIPMLARLFRY 561
G W +M A ER R++ + ADLVE+ LA +E+ + G+ + QA ++ + + RY
Sbjct: 90 LGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRY 149
Query: 562 YAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGPALACGNTIVL 741
YAGWADKIHG+T+P DG+Y T HEPIGV GQI+PWNFPLLMF WK+ PAL CGNT+V+
Sbjct: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVI 209
Query: 742 KTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKLAFTGSTDTGK 921
K AEQTPL+A Y+G L EAG PPGV+NI+ G+GPTAGA++ASH+ +DK+AFTGST+ GK
Sbjct: 210 KPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269
Query: 922 VVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQCCCAGSRTYVH 1101
++ A SNLK VTLELGGKSP I+F DAD++ AVE AH +FFNQGQCC AGSR +V
Sbjct: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329
Query: 1102 EKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGVESNATLECGG 1281
E +Y+EFV+++ RA +R+VG PF EQGPQID KQ+ KV+ I+SGV A LECGG
Sbjct: 330 ESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGG 389
Query: 1282 DQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRANETRYGLAAGV 1461
+G KG+FI+PTVFSNV DDM IA++EIFGPVQ IL+F+ +DEVI RAN + +GL A V
Sbjct: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449
Query: 1462 FTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQVNAV 1641
FT ++ A VS A++AGTVW+NC++ +A PFGG+KMSGNGRE G + L Y +V V
Sbjct: 450 FTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509
Query: 1642 VTPL 1653
+
Sbjct: 510 TVKI 513
>sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 OS=Rattus norvegicus GN=Aldh1a2
PE=1 SV=2
Length = 518
Score = 572 bits (1472), Expect = 5e-162
Identities = 268/484 (55%), Positives = 356/484 (73%), Gaps = 1/484 (0%)
Frame = +1
Query: 205 TPSVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINRAVKAARKAFD 384
TP++++ YT++ I+ + ++ SG+ FP +P TGE + V E D DI++AV+AAR AF
Sbjct: 30 TPNLEIKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFS 89
Query: 385 -GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTAEIPMLARLFRY 561
G W +M A ER R++ + ADLVE+ LA +E+ + G+ + QA ++ + + RY
Sbjct: 90 LGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRY 149
Query: 562 YAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGPALACGNTIVL 741
YAGWADKIHG+T+P DG+Y T HEPIGV GQI+PWNFPLLMF WK+ PAL CGNT+V+
Sbjct: 150 YAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVI 209
Query: 742 KTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKLAFTGSTDTGK 921
K AEQTPL+A Y+G L EAG PPGV+NI+ G+GPTAGA++ASH+ +DK+AFTGST+ GK
Sbjct: 210 KPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGK 269
Query: 922 VVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQCCCAGSRTYVH 1101
++ A SNLK VTLELGGKSP I+F DAD++ AVE AH +FFNQGQCC AGSR +V
Sbjct: 270 LIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVE 329
Query: 1102 EKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGVESNATLECGG 1281
E +Y+EFV+++ RA +R+VG PF EQGPQID KQ+ K++ I+SGV A LECGG
Sbjct: 330 ESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389
Query: 1282 DQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRANETRYGLAAGV 1461
+G KG+FI+PTVFSNV DDM IA++EIFGPVQ IL+F+ +DEVI RAN + +GL A V
Sbjct: 390 KGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAV 449
Query: 1462 FTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQVNAV 1641
FT ++ A VS A++AGTVW+NC++ +A PFGG+KMSGNGRE G + L Y +V V
Sbjct: 450 FTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTV 509
Query: 1642 VTPL 1653
+
Sbjct: 510 TVKI 513
>sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 OS=Oryctolagus cuniculus
GN=ALDH1A1 PE=2 SV=1
Length = 496
Score = 570 bits (1467), Expect = 2e-161
Identities = 272/490 (55%), Positives = 357/490 (72%), Gaps = 3/490 (0%)
Frame = +1
Query: 196 DIITP--SVQVSYTQLLIDGNFVDAASGKTFPTLDPRTGEVIANVAEGDAEDINRAVKAA 369
D+ TP ++++ YT++ I+ + D+ SGK FP L+P T E I + EGD D+++AVKAA
Sbjct: 3 DLPTPLTNLKIQYTKIFINNEWHDSVSGKKFPVLNPATEEQICLIEEGDKADVDKAVKAA 62
Query: 370 RKAFD-GGPWPKMTAYERSRIMLRFADLVEKHSEELAALETWDNGETYQQAKTAEIPMLA 546
R+AF G PW M A ER R++ + ADL+E+ LA +E+ + G+ + A ++
Sbjct: 63 RQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESLNAGKLFPNAYLMDLGGCI 122
Query: 547 RLFRYYAGWADKIHGLTVPADGNYHVQTLHEPIGVAGQIVPWNFPLLMFAWKVGPALACG 726
+ RY AGWADKI G T+P DG++ T HEP+GV GQI+PWNFPL+M WK+GPAL+CG
Sbjct: 123 KTLRYCAGWADKIQGRTMPMDGDFFCYTRHEPVGVCGQIIPWNFPLVMLIWKIGPALSCG 182
Query: 727 NTIVLKTAEQTPLTAFYVGKLFLEAGLPPGVLNIVSGFGPTAGASLASHMDVDKLAFTGS 906
NT+++K AEQTPLTA +V L EAG PPGV+NIV G+GPTAGA+++SHMD+DK+AFTGS
Sbjct: 183 NTVIVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGS 242
Query: 907 TDTGKVVLGLAANSNLKPVTLELGGKSPFIVFEDADINKAVELAHFALFFNQGQCCCAGS 1086
T+ GK++ A SNLK VTLELGGKSP IVF DAD++ AVE AH +F++QGQCC A S
Sbjct: 243 TEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAAS 302
Query: 1087 RTYVHEKVYDEFVEKAKARALKRVVGDPFKKGIEQGPQIDSKQFEKVMRYIRSGVESNAT 1266
R +V E +YDEFV ++ RA K V+G+P + QGPQID +Q+ K++ I SG + A
Sbjct: 303 RLFVEESIYDEFVRRSVERAKKYVLGNPLAPEVNQGPQIDKEQYNKILDLIESGKKEGAK 362
Query: 1267 LECGGDQIGNKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFRDVDEVIRRANETRYG 1446
LECGG GNKGYFIQPTVFSNV D+M IA++EIFGPVQ I+KF+ +D+VI+RAN T YG
Sbjct: 363 LECGGGPWGNKGYFIQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTTYG 422
Query: 1447 LAAGVFTKSLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYL 1626
L+AG+FTK LD A VS AL+AGTVWVNC+ V A +PFGG+KMSGNGRE G Y L Y
Sbjct: 423 LSAGIFTKDLDKAVTVSSALQAGTVWVNCYSVVSAQVPFGGFKMSGNGRELGEYGLQQYT 482
Query: 1627 QVNAVVTPLN 1656
+V V ++
Sbjct: 483 EVKTVTVKIS 492
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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