BLASTX 7.6.2
Query= UN19618 /QuerySize=968
(967 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NPD3|EXOS4_HUMAN Exosome complex exonuclease RRP41 OS=Homo ... 219 3e-056
sp|C5A2B9|ECX1_THEGJ Probable exosome complex exonuclease 1 OS=T... 206 2e-052
sp|B6YSI2|ECX1_THEON Probable exosome complex exonuclease 1 OS=T... 206 3e-052
sp|Q8U0L9|ECX1_PYRFU Probable exosome complex exonuclease 1 OS=P... 205 4e-052
sp|O59223|ECX1_PYRHO Probable exosome complex exonuclease 1 OS=P... 203 2e-051
sp|Q5JIR6|ECX1_PYRKO Probable exosome complex exonuclease 1 OS=P... 203 2e-051
sp|Q8TYC1|ECX1_METKA Probable exosome complex exonuclease 1 OS=M... 203 3e-051
sp|Q9V119|ECX1_PYRAB Probable exosome complex exonuclease 1 OS=P... 202 3e-051
sp|O26779|ECX1_METTH Probable exosome complex exonuclease 1 OS=M... 200 2e-050
sp|Q97BZ5|ECX1_THEVO Probable exosome complex exonuclease 1 OS=T... 196 2e-049
sp|Q4JB27|ECX1_SULAC Probable exosome complex exonuclease 1 OS=S... 193 2e-048
sp|Q9HIP2|ECX1_THEAC Probable exosome complex exonuclease 1 OS=T... 193 3e-048
sp|Q975G8|ECX1_SULTO Probable exosome complex exonuclease 1 OS=S... 192 5e-048
sp|A0RXU1|ECX1_CENSY Probable exosome complex exonuclease 1 OS=C... 190 2e-047
sp|Q9UXC2|ECX1_SULSO Probable exosome complex exonuclease 1 OS=S... 190 2e-047
sp|A2BKC0|ECX1_HYPBU Probable exosome complex exonuclease 1 OS=H... 184 7e-046
sp|Q8PTT8|ECX1_METMA Probable exosome complex exonuclease 1 OS=M... 184 9e-046
sp|O29757|ECX1_ARCFU Probable exosome complex exonuclease 1 OS=A... 181 1e-044
sp|Q9YC03|ECX1_AERPE Probable exosome complex exonuclease 1 OS=A... 170 1e-041
>sp|Q9NPD3|EXOS4_HUMAN Exosome complex exonuclease RRP41 OS=Homo sapiens
GN=EXOSC4 PE=1 SV=3
Length = 245
Score = 219 bits (557), Expect = 3e-056
Identities = 113/235 (48%), Positives = 167/235 (71%), Gaps = 3/235 (1%)
Frame = -2
Query: 864 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQ-NKS 688
+E ++ +G R+DGRR E+R+I A +GV ++ADGSA E GNTK +A VYGP EI+ +++
Sbjct: 4 LELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRA 63
Query: 687 QQKNGHALVLCEYSMAHFSTGDR-RRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDI 511
+ ALV C+YS A FSTG+R RR DR+S E+ L +RQT EA ILT+L P SQIDI
Sbjct: 64 RALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQIDI 123
Query: 510 FLQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGA 334
++QVLQA GGT +AC+NAATLA+ DAGIPMRD +CSAG+++ T L DL++VE++AGG
Sbjct: 124 YVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAAGGP 183
Query: 333 DVTVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQENTKQ 169
+ + +LP ++ LL+MDA+L + E V A++ + + + V++++ ++
Sbjct: 184 QLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVRE 238
>sp|C5A2B9|ECX1_THEGJ Probable exosome complex exonuclease 1 OS=Thermococcus
gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) GN=TGAM_2036 PE=3
SV=1
Length = 249
Score = 206 bits (523), Expect = 2e-052
Identities = 110/229 (48%), Positives = 153/229 (66%), Gaps = 1/229 (0%)
Frame = -2
Query: 864 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 685
++ ++ G R+DGRR E+R+I EVGV+ ADGSA E G K++AAVYGPREI K
Sbjct: 8 LKLIDENGRRIDGRRKYELRKIHMEVGVLKNADGSAYIEWGKNKILAAVYGPREIHPKHL 67
Query: 684 QKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFL 505
Q+ A++ Y+MA FS +R++ DRRS E+S VIR +E ++ E+ P + +D+F+
Sbjct: 68 QRPDTAVLRVRYNMAPFSVEERKKPGPDRRSVEISKVIRGALEPALILEMFPRTVVDVFI 127
Query: 504 QVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADV 328
+VLQA GTR A I AA+LALADAG+PMRDL +C+AG ++ +LDLN ED+ G ADV
Sbjct: 128 EVLQADAGTRVAGITAASLALADAGVPMRDLVAACAAGKIDGEIVLDLNKDEDNYGEADV 187
Query: 327 TVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
V I+P + +TLLQMD L E F LA +G KA+ ++ RE L+E
Sbjct: 188 PVAIMPLKNDITLLQMDGYLTKEEFIEAVKLAIKGAKAVYQKQREALKE 236
>sp|B6YSI2|ECX1_THEON Probable exosome complex exonuclease 1 OS=Thermococcus
onnurineus (strain NA1) GN=TON_0030 PE=3 SV=1
Length = 249
Score = 206 bits (522), Expect = 3e-052
Identities = 111/229 (48%), Positives = 151/229 (65%), Gaps = 1/229 (0%)
Frame = -2
Query: 864 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 685
++ ++ G R+DGR+ E+R I EVGV+ ADGSA E G K++AAVYGPREI K
Sbjct: 8 LKLIDENGRRIDGRKKYELRPIKMEVGVLKNADGSAYVEWGKNKILAAVYGPREIHPKHL 67
Query: 684 QKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFL 505
Q+ A++ Y+MA FS +R++ DRRS E+S VIR +E ++ E+ P + IDIF+
Sbjct: 68 QRPDRAILRVRYNMAPFSVEERKKPGPDRRSVEISKVIRGALEPALILEMFPRTAIDIFI 127
Query: 504 QVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADV 328
+VLQA GTR A I AA+LALADAGIPMRDL +C+AG + +LDLN ED+ G ADV
Sbjct: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADV 187
Query: 327 TVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
V I+P + +TLLQMD L + F LA +G KA+ ++ RE L+E
Sbjct: 188 PVAIMPLKNDITLLQMDGYLTRDEFIEAVRLAIKGAKAVYQKQREALKE 236
>sp|Q8U0L9|ECX1_PYRFU Probable exosome complex exonuclease 1 OS=Pyrococcus
furiosus GN=PF1568 PE=3 SV=1
Length = 250
Score = 205 bits (521), Expect = 4e-052
Identities = 112/229 (48%), Positives = 151/229 (65%), Gaps = 1/229 (0%)
Frame = -2
Query: 864 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 685
++ ++ G RLDGR+ E+R I +VGV+ A+GSA E G K+IAAVYGPREI K
Sbjct: 8 LKLIDENGRRLDGRKKYELRPIKMKVGVLKNANGSAYIEWGKNKIIAAVYGPREIHPKHL 67
Query: 684 QKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFL 505
Q+ A++ Y+MA FS +R++ DRRS E+S VIR +E ++ E+ P + ID+F+
Sbjct: 68 QRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIRGALEPALILEMFPRTAIDVFI 127
Query: 504 QVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADV 328
+VLQA GTR A I AA+LALADAGIPMRDL +CSAG + +LDLN ED+ G ADV
Sbjct: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACSAGKIEGEIVLDLNKEEDNYGEADV 187
Query: 327 TVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
V I+P + +TLLQMD L E F LA +G KA+ ++ RE L+E
Sbjct: 188 PVAIMPIKNDITLLQMDGYLTKEEFIEAVKLAIKGAKAVYQKQREALKE 236
>sp|O59223|ECX1_PYRHO Probable exosome complex exonuclease 1 OS=Pyrococcus
horikoshii GN=PH1549 PE=3 SV=1
Length = 249
Score = 203 bits (516), Expect = 2e-051
Identities = 108/229 (47%), Positives = 152/229 (66%), Gaps = 1/229 (0%)
Frame = -2
Query: 864 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 685
++ ++ G R+DGR+ E+R I +VGV+ A+GSA E G K+IAAVYGPRE+ +K
Sbjct: 8 LKLIDENGRRIDGRKKYELRPIKMKVGVLKNANGSAYIEWGRNKIIAAVYGPRELHSKHL 67
Query: 684 QKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFL 505
Q+ A++ Y+MA FS +R++ DRRS E+S VI+ +E ++ E+ P + ID+F+
Sbjct: 68 QRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTSIDVFI 127
Query: 504 QVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADV 328
+VLQA GTR A I AA+LALADAGIPMRDL +C+AG + +LDLN ED+ G ADV
Sbjct: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADV 187
Query: 327 TVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
V I+P + +TLLQMD L E F LA +G KA+ ++ RE L+E
Sbjct: 188 PVAIMPLKNDITLLQMDGYLTKEEFIEAVRLAIKGAKAVYQKQREALKE 236
>sp|Q5JIR6|ECX1_PYRKO Probable exosome complex exonuclease 1 OS=Pyrococcus
kodakaraensis GN=TK1634 PE=3 SV=1
Length = 249
Score = 203 bits (516), Expect = 2e-051
Identities = 109/229 (47%), Positives = 151/229 (65%), Gaps = 1/229 (0%)
Frame = -2
Query: 864 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 685
++ ++ G R+DGR+ E+R I EVGV+ ADGSA E G KV+AAVYGPREI K
Sbjct: 8 LKLIDENGKRIDGRKKYELRPIKMEVGVLKNADGSAYVEWGKNKVLAAVYGPREIHPKHL 67
Query: 684 QKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFL 505
Q+ A++ Y+MA FS +R++ DRRS E+S VIR +E +L + P + ID+F+
Sbjct: 68 QRPDRAILRVRYNMAPFSVEERKKPGPDRRSVEISKVIRGALEPALLLHMFPRTAIDVFI 127
Query: 504 QVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADV 328
++LQA GTR A I AA+LALADAGIPM+DL +C+AG ++ +LDLN ED+ G ADV
Sbjct: 128 EILQADAGTRVAGITAASLALADAGIPMKDLVAACAAGKIDGEIVLDLNKEEDNYGEADV 187
Query: 327 TVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
V I+P + +TLLQMD L + F LA +G KA+ ++ RE L+E
Sbjct: 188 PVAIMPLKNDITLLQMDGYLTKDEFLEAVRLAIKGAKAVYQKQREALKE 236
>sp|Q8TYC1|ECX1_METKA Probable exosome complex exonuclease 1 OS=Methanopyrus
kandleri GN=MK0381 PE=3 SV=1
Length = 239
Score = 203 bits (514), Expect = 3e-051
Identities = 106/226 (46%), Positives = 150/226 (66%), Gaps = 1/226 (0%)
Frame = -2
Query: 855 VNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQQKN 676
++ +GLRLDGR+ +EMR + + GV+ +ADGSA E+G K++AAVYGPRE+ + +QK
Sbjct: 9 ISEDGLRLDGRKPDEMRPLKIQAGVLKRADGSAYLELGANKIVAAVYGPRELHPRHKQKP 68
Query: 675 GHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFLQVL 496
A+V Y+MA FS +R+R DRRS E+S + ++ +E I TE P + IDIF++VL
Sbjct: 69 DRAVVRFRYNMAPFSVDERKRPGPDRRSIEISKLSKEALEPAIFTEYYPRTAIDIFVEVL 128
Query: 495 QA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADVTVG 319
QA GTR A I+AA++ALADAGI MRDL +C+AG + +LD Y ED G ADV +
Sbjct: 129 QADAGTRCAGISAASVALADAGIEMRDLVAACAAGKVEGKVVLDPMYYEDGYGEADVPLA 188
Query: 318 ILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
++PK K+TLLQMD + F+ LA +GCK + + R L+E
Sbjct: 189 MMPKEGKITLLQMDGDMTPGEFKQAVKLAKKGCKIVYKEQRRALKE 234
>sp|Q9V119|ECX1_PYRAB Probable exosome complex exonuclease 1 OS=Pyrococcus
abyssi GN=PYRAB06100 PE=1 SV=1
Length = 249
Score = 202 bits (513), Expect = 3e-051
Identities = 108/229 (47%), Positives = 151/229 (65%), Gaps = 1/229 (0%)
Frame = -2
Query: 864 MEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQ 685
++ ++ G R+DGR+ E+R I EVGV+ A+GSA E G K+IAAVYGPRE+ K
Sbjct: 8 LKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHL 67
Query: 684 QKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFL 505
Q+ A++ Y+MA FS +R++ DRRS E+S VI+ +E ++ E+ P + ID+F+
Sbjct: 68 QRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFI 127
Query: 504 QVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADV 328
+VLQA GTR A I AA+LALADAGIPMRDL +C+AG + +LDLN ED+ G ADV
Sbjct: 128 EVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADV 187
Query: 327 TVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
V I+P + +TLLQMD L + F LA +G KA+ ++ RE L+E
Sbjct: 188 PVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKE 236
>sp|O26779|ECX1_METTH Probable exosome complex exonuclease 1 OS=Methanobacterium
thermoautotrophicum GN=MTH_683 PE=1 SV=1
Length = 240
Score = 200 bits (506), Expect = 2e-050
Identities = 103/221 (46%), Positives = 144/221 (65%), Gaps = 1/221 (0%)
Frame = -2
Query: 840 LRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQQKNGHALV 661
+R DGR F+E+R + E G++ +ADGS+ E G K++ AVYGPRE Q + Q+ A++
Sbjct: 16 VREDGRAFDELRPLKIEAGILERADGSSYLEFGGNKILVAVYGPREAQIRKLQRPDRAVI 75
Query: 660 LCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFLQVLQA-GG 484
C Y+MA FS +R+R DRRS E+S + + + ++ E P S ID+F++VL+A GG
Sbjct: 76 RCRYNMAPFSVEERKRPGPDRRSVEISKITAEALRPALILEKFPRSVIDVFIEVLEAEGG 135
Query: 483 TRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADVTVGILPKL 304
TR A I AA++ALADAGIPMRD+ V+C+AG + +LDL+ ED G ADV V ILP+
Sbjct: 136 TRCAGITAASVALADAGIPMRDMVVACAAGKVGDQVVLDLSEEEDKEGQADVPVAILPRT 195
Query: 303 DKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
++TLLQ D L E FE LA EGC I E +E L++
Sbjct: 196 REITLLQSDGNLTPEEFERALDLAVEGCLRIHEVQKEALRK 236
>sp|Q97BZ5|ECX1_THEVO Probable exosome complex exonuclease 1 OS=Thermoplasma
volcanium (strain ATCC 51530 / DSM 4299 / IFO 15438 / JCM 9571 / GSS1)
GN=TV0310 PE=3 SV=1
Length = 248
Score = 196 bits (497), Expect = 2e-049
Identities = 102/233 (43%), Positives = 149/233 (63%), Gaps = 1/233 (0%)
Frame = -2
Query: 867 RMEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKS 688
+++ +N + LRLDGR FNE+R I E GV+++ADGSA E G K+I VYGP+E K
Sbjct: 8 KIKLINEDNLRLDGRSFNELRPIKIEAGVLNRADGSAYIEWGGNKIIVGVYGPKEAYPKH 67
Query: 687 QQKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIF 508
Q HA+V Y+MA FS +R+R DRR+ E+S VI + + + I+ E P ++ID++
Sbjct: 68 SQDIDHAVVKARYNMAAFSVDERKRPGPDRRTMEISKVISEALSSSIMIEQFPRAEIDVY 127
Query: 507 LQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGAD 331
++VLQA GTR A + AAT+ALADAGIPMRD+ V C+AG ++ +LDL+ ED+ G AD
Sbjct: 128 IEVLQADAGTRIAGLTAATVALADAGIPMRDMVVGCTAGKVDGHIVLDLSKEEDNFGEAD 187
Query: 330 VTVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQENTK 172
+ + I+PK ++ LLQMD + + F ++ E K I++ R L K
Sbjct: 188 IPMAIMPKTGEIVLLQMDGDVTEDEFYEATSMIIEATKKISQIQRNALLNKYK 240
>sp|Q4JB27|ECX1_SULAC Probable exosome complex exonuclease 1 OS=Sulfolobus
acidocaldarius GN=Saci_0610 PE=3 SV=1
Length = 243
Score = 193 bits (490), Expect = 2e-048
Identities = 108/239 (45%), Positives = 149/239 (62%), Gaps = 3/239 (1%)
Frame = -2
Query: 870 QRMEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNK 691
Q+ + + GLR DGR+ +E+R I E+GV+ ADGSA+FEMGNTKVIAAVYGP+E+ +
Sbjct: 5 QKPKLILENGLRTDGRKLDELRPIKIELGVLKNADGSAIFEMGNTKVIAAVYGPKEMHPR 64
Query: 690 SQQKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDI 511
A + Y M FST +R+ RR ELS VIR+ +E+ IL L P + IDI
Sbjct: 65 HLALPDKASLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESTILLNLFPRTVIDI 124
Query: 510 FLQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGA 334
F++VLQA GTR + AA++ALADAGIPMRDL + G + + +LDLN ED G A
Sbjct: 125 FMEVLQADAGTRLVALMAASMALADAGIPMRDLIAGVAVGKADGSLVLDLNEQEDMWGEA 184
Query: 333 DVTVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQENTKQLEYR 157
D+ + +LP L +V LLQ++ + + F F LA +G +I +E L+ K LEY+
Sbjct: 185 DMPIAVLPSLGQVVLLQLNGFMTPDEFRRAFELAQKGISSIYALQKEALK--NKYLEYK 241
>sp|Q9HIP2|ECX1_THEAC Probable exosome complex exonuclease 1 OS=Thermoplasma
acidophilum GN=Ta1293 PE=3 SV=1
Length = 248
Score = 193 bits (488), Expect = 3e-048
Identities = 98/233 (42%), Positives = 147/233 (63%), Gaps = 1/233 (0%)
Frame = -2
Query: 867 RMEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKS 688
+++ +N + LRLDGR FNE+R I + GV+++ADGSA E G K++ VYGP+E K
Sbjct: 8 KIKLINEDNLRLDGRSFNELRPIKIQAGVLNRADGSAYIEWGGNKIMVGVYGPKEAYPKH 67
Query: 687 QQKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIF 508
Q HA+V Y+MA FS +R+R DRR+ E+S VI + + + I+ E P ++ID++
Sbjct: 68 SQDIDHAIVKARYNMAAFSVDERKRPGPDRRTMEISKVISEALSSSIMIEQFPRAEIDVY 127
Query: 507 LQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGAD 331
++VLQA GTR A + AAT+ALADAG+PMRD+ V C+AG ++ +LDL+ ED+ G AD
Sbjct: 128 IEVLQADAGTRIAGLTAATVALADAGVPMRDMVVGCTAGKVDGHMVLDLSKEEDNYGEAD 187
Query: 330 VTVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQENTK 172
+ + I+PK + L+QMD + + + E K I++ RE L K
Sbjct: 188 IPIAIMPKTGDIVLMQMDGDVTEDELYQAMDMIFEATKRISQIQREALLNKYK 240
>sp|Q975G8|ECX1_SULTO Probable exosome complex exonuclease 1 OS=Sulfolobus
tokodaii GN=ST0443 PE=3 SV=1
Length = 247
Score = 192 bits (486), Expect = 5e-048
Identities = 104/237 (43%), Positives = 147/237 (62%), Gaps = 1/237 (0%)
Frame = -2
Query: 870 QRMEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNK 691
Q+ + GLRLDGR+ +EMR I E+GV+ ADGSA+FEMGNTKVIAAVYGP+E+ +
Sbjct: 9 QKPRLILDNGLRLDGRKPDEMRPIKIELGVLKNADGSAIFEMGNTKVIAAVYGPKEMHPR 68
Query: 690 SQQKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDI 511
A++ Y M FST +R+ RR ELS VIR+ +E+ IL EL P + ID+
Sbjct: 69 HLALPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESTILVELFPRTVIDV 128
Query: 510 FLQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGA 334
F++VLQA GTR + AA++ALADAGIPMRDL + G + +LDLN ED G A
Sbjct: 129 FMEVLQADAGTRLVSLMAASMALADAGIPMRDLIAGVAVGKADGVLVLDLNEPEDMWGEA 188
Query: 333 DVTVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQENTKQLE 163
D+ V ++P L +V LLQ++ + + F +A +G + I +E ++ +L+
Sbjct: 189 DMPVAMMPSLKQVALLQLNGNMTPQEFRQALEMAQKGIETIYNLEKEAIRSKYAELK 245
>sp|A0RXU1|ECX1_CENSY Probable exosome complex exonuclease 1 OS=Cenarchaeum
symbiosum GN=CENSYa_1536 PE=3 SV=1
Length = 243
Score = 190 bits (481), Expect = 2e-047
Identities = 90/226 (39%), Positives = 148/226 (65%), Gaps = 1/226 (0%)
Frame = -2
Query: 855 VNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQQKN 676
++ G+R DGR+ +E R++ GV++ A+GSA E G+ K++A ++GPR++ K +
Sbjct: 11 LDENGIRCDGRKISETRRVEITAGVLNNANGSAYIEFGDNKILAGIFGPRDVHPKHMVRT 70
Query: 675 GHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFLQVL 496
++ C Y M+ FS +R++ RR E+S VI++ +E ++ E P + +D+F++VL
Sbjct: 71 ETGILRCRYHMSPFSVSERKKPAPSRREIEISKVIKEALEPSLMLEQFPRTAVDVFIEVL 130
Query: 495 QA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADVTVG 319
QA GG+R A + AA++ALADAGIPMRD+ +C+AG + T +LD+N ED AG AD+ VG
Sbjct: 131 QADGGSRCAALAAASVALADAGIPMRDMVSACAAGKVADTIVLDVNNEEDQAGQADMPVG 190
Query: 318 ILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
+P LD+VTL+Q+D L + + A+A +GCK + E ++ L +
Sbjct: 191 YMPNLDQVTLIQLDGVLTPDEYSRCAAMAIDGCKQVYEVQKKALSD 236
>sp|Q9UXC2|ECX1_SULSO Probable exosome complex exonuclease 1 OS=Sulfolobus
solfataricus GN=SSO0735 PE=1 SV=1
Length = 248
Score = 190 bits (480), Expect = 2e-047
Identities = 102/239 (42%), Positives = 149/239 (62%), Gaps = 3/239 (1%)
Frame = -2
Query: 870 QRMEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNK 691
+R + + +G R DGR+ +E+R I E+GV+ ADGSA+FEMGNTK IAAVYGP+E+ +
Sbjct: 8 ERPKLILDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPR 67
Query: 690 SQQKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDI 511
A++ Y M FST +R+ RR ELS VIR+ +E+ +L EL P + ID+
Sbjct: 68 HLSLPDRAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVELFPRTAIDV 127
Query: 510 FLQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGA 334
F ++LQA G+R + AA+LALADAGIPMRDL + G + +LDLN ED G A
Sbjct: 128 FTEILQADAGSRLVSLMAASLALADAGIPMRDLIAGVAVGKADGVIILDLNETEDMWGEA 187
Query: 333 DVTVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQENTKQLEYR 157
D+ + ++P L++VTL Q++ + + F F LA +G I RE L+ +K +E++
Sbjct: 188 DMPIAMMPSLNQVTLFQLNGSMTPDEFRQAFDLAVKGINIIYNLEREALK--SKYVEFK 244
>sp|A2BKC0|ECX1_HYPBU Probable exosome complex exonuclease 1 OS=Hyperthermus
butylicus (strain DSM 5456 / JCM 9403) GN=Hbut_0571 PE=3 SV=1
Length = 255
Score = 184 bits (467), Expect = 7e-046
Identities = 100/221 (45%), Positives = 142/221 (64%), Gaps = 1/221 (0%)
Frame = -2
Query: 840 LRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQQKNGHALV 661
+R DGR ++R I EVGV+S ADGSA+ E G T+VIAAVYGPRE + A++
Sbjct: 24 IRHDGRLPEQLRPIRMEVGVLSNADGSALVEYGGTRVIAAVYGPREAHPRHVALPDRAII 83
Query: 660 LCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFLQVLQA-GG 484
C Y MA FST +R+ RR ELS VIR+ +EA +++EL P + ID++++VLQ+ GG
Sbjct: 84 RCRYHMAPFSTAERKTPAPTRREVELSKVIREALEAVVISELYPRTAIDVYMEVLQSDGG 143
Query: 483 TRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADVTVGILPKL 304
TR+A I AA+LALADAGI MRDL + G ++ +LD++ +ED+ AD+ V + P L
Sbjct: 144 TRTAAITAASLALADAGIAMRDLVAGVAVGKVDGVLVLDIDEIEDNYAEADMPVAMAPSL 203
Query: 303 DKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
DKV LLQ++ L + F LA +G + I +E L++
Sbjct: 204 DKVLLLQLNGVLTHDEFVKALELARKGIQVIYNLQKEALRK 244
>sp|Q8PTT8|ECX1_METMA Probable exosome complex exonuclease 1 OS=Methanosarcina
mazei GN=MM_2623 PE=3 SV=1
Length = 493
Score = 184 bits (466), Expect = 9e-046
Identities = 101/231 (43%), Positives = 145/231 (62%), Gaps = 2/231 (0%)
Frame = -2
Query: 870 QRMEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNK 691
+ + + +GLRLDGRR +E+R + EVGV+S+ADGS E G K++ V+GPRE +
Sbjct: 6 ENLTLITDDGLRLDGRRADEIRPMKIEVGVLSRADGSCYLEWGRNKILVGVFGPREAHPR 65
Query: 690 SQQKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDI 511
Q+ A++ Y+MA FS DR R RRS E+S V R+ E I+ EL P + IDI
Sbjct: 66 RSQRADSAVIRYRYNMASFSVEDRARPGPSRRSIEISKVSREAFEPVIMAELFPKTAIDI 125
Query: 510 FLQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGA 334
F++VLQA GTR+A INA+++ALADAGIPM+ L SC+ G ++ +LDLN ED+ G A
Sbjct: 126 FVEVLQADAGTRTAAINASSIALADAGIPMKGLITSCAFGKVDGKIVLDLNKEEDNYGEA 185
Query: 333 DVTVGILPKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQE 181
D V + + ++TL+QMD L + + L +GCK I E + VL++
Sbjct: 186 DFPVA-MTQDGEITLIQMDGNLTPDEIKQGLELVKKGCKEILEIQQAVLRK 235
>sp|O29757|ECX1_ARCFU Probable exosome complex exonuclease 1 OS=Archaeoglobus
fulgidus GN=AF_0493 PE=1 SV=1
Length = 258
Score = 181 bits (457), Expect = 1e-044
Identities = 99/232 (42%), Positives = 144/232 (62%), Gaps = 4/232 (1%)
Frame = -2
Query: 870 QRMEYVNPEGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNK 691
++ E + +GLRLDGR+F+E+R I E V+ +ADGS EMG KVIAAV+GPRE+ +
Sbjct: 6 EKPEKLIVDGLRLDGRKFDELRPIKIEASVLKRADGSCYLEMGKNKVIAAVFGPREVHPR 65
Query: 690 SQQKNGHALVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDI 511
Q A++ Y+MA FS +R+R DRRS E+S V ++ EA I+ EL P S IDI
Sbjct: 66 HLQDPSKAIIRYRYNMAPFSVEERKRPGPDRRSIEISKVSKEAFEAVIMKELFPRSAIDI 125
Query: 510 FLQVLQA-GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGA 334
F++VLQA G+R+AC+NAA++AL DAG+PM+ + S + G + +LD ED+ G A
Sbjct: 126 FVEVLQADAGSRTACLNAASVALVDAGVPMKGMITSVAVGKADGQLVLDPMKEEDNFGEA 185
Query: 333 DVTVGIL---PKLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVL 187
D+ L K++ + LLQMD ++ + + LA +G I E RE +
Sbjct: 186 DMPFAFLIRNGKIESIALLQMDGRMTRDEVKQAIELAKKGALQIYEMQREAI 237
>sp|Q9YC03|ECX1_AERPE Probable exosome complex exonuclease 1 OS=Aeropyrum pernix
GN=APE_1447 PE=3 SV=1
Length = 246
Score = 170 bits (430), Expect = 1e-041
Identities = 92/224 (41%), Positives = 136/224 (60%), Gaps = 1/224 (0%)
Frame = -2
Query: 846 EGLRLDGRRFNEMRQIVAEVGVVSKADGSAVFEMGNTKVIAAVYGPREIQNKSQQKNGHA 667
+G R DGR ++R + +VG++ ADGSA+ E G T+V+AAVYGPRE + A
Sbjct: 14 DGRRHDGRLPEDLRPVRMQVGILHNADGSALVEFGRTRVLAAVYGPREPHQRFYVLPDRA 73
Query: 666 LVLCEYSMAHFSTGDRRRQKNDRRSTELSLVIRQTMEACILTELLPHSQIDIFLQVLQA- 490
+ Y MA FST +R+ RR ELS V+R+ +E +L E P + ID+FL+VLQA
Sbjct: 74 ALRVRYHMAPFSTDERKSPAPSRREIELSKVVREALEPVVLAEEFPRTVIDVFLEVLQAD 133
Query: 489 GGTRSACINAATLALADAGIPMRDLAVSCSAGYLNSTPLLDLNYVEDSAGGADVTVGILP 310
GGTR+A + AA+LALADAGIPMR L + G + ++D++ +ED G AD+ V P
Sbjct: 134 GGTRTAAVTAASLALADAGIPMRALVGGVAVGKIQGVLVVDVDELEDMYGEADMPVAAAP 193
Query: 309 KLDKVTLLQMDAKLPMETFETVFALASEGCKAIAERVREVLQEN 178
+ ++TLLQ++ L E F T A+A + E +E ++++
Sbjct: 194 DIGEITLLQLNGVLTGEEFRTALAMALRAIDRVVEMEKEAIRKS 237
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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