BLASTX 7.6.2
Query= UN19718 /QuerySize=1289
(1288 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6TGY8|TTC35_DANRE Tetratricopeptide repeat protein 35 OS=Dan... 186 5e-046
sp|Q6INS3|TC35A_XENLA Tetratricopeptide repeat protein 35-A OS=X... 182 7e-045
sp|Q8AVU9|TC35B_XENLA Tetratricopeptide repeat protein 35-B OS=X... 179 3e-044
sp|Q5M7J9|TTC35_XENTR Tetratricopeptide repeat protein 35 OS=Xen... 179 5e-044
sp|Q5R882|TTC35_PONAB Tetratricopeptide repeat protein 35 OS=Pon... 177 2e-043
sp|Q9CRD2|TTC35_MOUSE Tetratricopeptide repeat protein 35 OS=Mus... 176 3e-043
sp|B0BNG0|TTC35_RAT Tetratricopeptide repeat protein 35 OS=Rattu... 176 5e-043
sp|Q15006|TTC35_HUMAN Tetratricopeptide repeat protein 35 OS=Hom... 175 9e-043
sp|Q5E993|TTC35_BOVIN Tetratricopeptide repeat protein 35 OS=Bos... 174 1e-042
sp|O60110|OCA3_SCHPO TPR repeat protein oca3 OS=Schizosaccharomy... 113 4e-024
>sp|Q6TGY8|TTC35_DANRE Tetratricopeptide repeat protein 35 OS=Danio rerio
GN=ttc35 PE=2 SV=1
Length = 297
Score = 186 bits (470), Expect = 5e-046
Identities = 104/278 (37%), Positives = 165/278 (59%), Gaps = 11/278 (3%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE ++ G ++N+ S LG D W +YEQV IAA+DC ++ +C++ L+
Sbjct: 23 REENYRNSEQIVDVGEELINE--HASKLGDDIWIIYEQVMIAALDCSRDDLAWSCLQELK 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP+S RV +L + +EA +++A K Y +L+D+P + KRK+ + +AQGK S A
Sbjct: 81 RQFPDSHRVKRLAGMRLEALERYDDANKLYDSILQDDPTNTAARKRKICILRAQGKSSEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW EL+E+Y++ Y +AAFC EEL+++ P LY YA++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELSELYINEHDYAKAAFCLEELMMTNPHNHLYCEQYAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKDMAAPGLQ 873
T GGLENL ARKY+A + L ++ RALFG+ + S IA + K KD
Sbjct: 201 TQGGLENLELARKYFAQALKL-NNRNMRALFGLYMSASHIAASPKVSAKVKKDNVK--YA 257
Query: 874 SLAATALEKEY------KQKSPAKLNLLTSALRSLKMS 969
+ AA + + Y K+++ + + L SL+++
Sbjct: 258 AWAAAQISRAYQMAGRGKKENKCSVKAVEEMLESLQIT 295
>sp|Q6INS3|TC35A_XENLA Tetratricopeptide repeat protein 35-A OS=Xenopus laevis
GN=ttc35-a PE=2 SV=1
Length = 297
Score = 182 bits (460), Expect = 7e-045
Identities = 101/252 (40%), Positives = 154/252 (61%), Gaps = 5/252 (1%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE V++ G ++N+ S LG D W +YEQV IAA+DC ++ +C++ L+
Sbjct: 23 REENYRNSEHVIEVGEELINE--HASKLGDDIWIIYEQVMIAALDCGRDDIAMSCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L L EA +++A + Y +L+D+P + KRK+A+ KAQG+ S A
Sbjct: 81 RQFPGSHRVKRLTGLRFEAMERYDDALQIYDRILQDDPTNTAARKRKIAIRKAQGRNSEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EELIL+ P Y+ +A++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINELDYAKAAFCLEELILTNPHNHFYYQQFAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKDMAAPGLQ 873
T GGLENL +RKY++ + L + RALFG+ + IA + K KD
Sbjct: 201 TQGGLENLELSRKYFSQALKL-NNHNMRALFGLYISSVHIASNPKASAKMKKDNVK--YA 257
Query: 874 SLAATALEKEYK 909
+ AA+ ++K Y+
Sbjct: 258 TWAASQIKKAYQ 269
>sp|Q8AVU9|TC35B_XENLA Tetratricopeptide repeat protein 35-B OS=Xenopus laevis
GN=ttc35-b PE=2 SV=1
Length = 297
Score = 179 bits (454), Expect = 3e-044
Identities = 96/233 (41%), Positives = 144/233 (61%), Gaps = 3/233 (1%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE ++ G ++N+ S LG D W +YEQV IAA+DC ++ +C++ L+
Sbjct: 23 REDNYRNSEQIVDVGEELINE--HASKLGDDVWIIYEQVMIAALDCGRDDIAMSCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L L EA +++A + Y +L+D+P + KRK+A+ KAQG+ + A
Sbjct: 81 RQFPGSHRVKRLTGLRFEAMERYDDALQIYDRILQDDPTNTATRKRKIAIRKAQGRNAEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EELIL+ P Y+ +A++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINELDYAKAAFCLEELILTNPHNHFYYQQFAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKD 852
T GGLENL +RKY++ + L S RALFG+ + IA + K KD
Sbjct: 201 TQGGLENLELSRKYFSQALKL-NNHSMRALFGLYMSSVHIASNPKASAKMKKD 252
>sp|Q5M7J9|TTC35_XENTR Tetratricopeptide repeat protein 35 OS=Xenopus tropicalis
GN=ttc35 PE=2 SV=1
Length = 297
Score = 179 bits (453), Expect = 5e-044
Identities = 96/233 (41%), Positives = 145/233 (62%), Gaps = 3/233 (1%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE V++ G ++N+ S LG D W +YEQV IAA+DC ++ +C++ L+
Sbjct: 23 REENYRNSEHVIEVGEELINE--HASKLGDDIWIIYEQVMIAALDCGRDDIAMSCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L L EA +++A + Y +L+D+P + KRK+A+ KAQG+ + A
Sbjct: 81 RQFPGSHRVKRLTGLRFEAMERYDDALQIYDRILQDDPTNTAARKRKIAIRKAQGRNAEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EELIL+ P Y+ +A++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINELDYAKAAFCLEELILTNPHNHFYYQQFAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKD 852
T GGLENL +RKY++ + L + RALFG+ + IA + K KD
Sbjct: 201 TQGGLENLELSRKYFSQALKL-NNHNMRALFGLYISSVHIASNPKASAKMKKD 252
>sp|Q5R882|TTC35_PONAB Tetratricopeptide repeat protein 35 OS=Pongo abelii
GN=TTC35 PE=2 SV=1
Length = 297
Score = 177 bits (448), Expect = 2e-043
Identities = 104/278 (37%), Positives = 164/278 (58%), Gaps = 11/278 (3%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE +++ G ++N+ G S LG D W +YEQV IAA+D ++ C++ L+
Sbjct: 23 REENSRNSEQIVEVGEELINEYG--SKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L + EA +++A + Y +L+++P + KRK+A+ KAQGK A
Sbjct: 81 RQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EEL+++ P LY YA++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKDMAAPGLQ 873
T GGLENL +RKY+A + L ++ RALFG+ + S IA + K KD
Sbjct: 201 TQGGLENLELSRKYFAQALKL-NNRNMRALFGLYMSASHIASNPKASAKTKKDNMK--YA 257
Query: 874 SLAATALEKEY------KQKSPAKLNLLTSALRSLKMS 969
S AA+ + + Y K+++ L + L +L+++
Sbjct: 258 SWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQIT 295
>sp|Q9CRD2|TTC35_MOUSE Tetratricopeptide repeat protein 35 OS=Mus musculus
GN=Ttc35 PE=2 SV=1
Length = 297
Score = 176 bits (446), Expect = 3e-043
Identities = 104/278 (37%), Positives = 162/278 (58%), Gaps = 11/278 (3%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE +++ G ++ND S LG D W +YEQV IAA+D ++ C++ L+
Sbjct: 23 REENSRNSEQIMEVGEELIND--YASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L + EA +++A + Y +L+++P + KRK+A+ KAQGK A
Sbjct: 81 RQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKTVEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EEL+++ P LY YA++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKDMAAPGLQ 873
T GGLENL +RKY+A + L ++ RALFG+ + S IA + K KD
Sbjct: 201 TQGGLENLELSRKYFAQALKL-NNRNMRALFGLYMSASHIASNPKASAKMKKDNIK--YA 257
Query: 874 SLAATALEKEY------KQKSPAKLNLLTSALRSLKMS 969
S AA + + Y K+++ L + L +L+++
Sbjct: 258 SWAANQINRAYQFAGRSKKETKYSLKAVEDMLETLQIT 295
>sp|B0BNG0|TTC35_RAT Tetratricopeptide repeat protein 35 OS=Rattus norvegicus
GN=Ttc35 PE=2 SV=1
Length = 297
Score = 176 bits (444), Expect = 5e-043
Identities = 103/278 (37%), Positives = 162/278 (58%), Gaps = 11/278 (3%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE +++ G ++ND S LG D W +YEQV IAA+D ++ C++ L+
Sbjct: 23 REENSRNSEQIMEVGEELIND--YASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L + EA +++A + Y +L+++P + KRK+A+ KAQGK A
Sbjct: 81 RQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EEL+++ P LY YA++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKDMAAPGLQ 873
T GGLENL +RKY+A + L ++ RALFG+ + S IA + K KD
Sbjct: 201 TQGGLENLELSRKYFAQALKL-NNRNMRALFGLYMSASHIASNPKASAKMKKDNIR--YA 257
Query: 874 SLAATALEKEY------KQKSPAKLNLLTSALRSLKMS 969
AA + + Y K+++ + L + L +L+++
Sbjct: 258 GWAANQINRAYQFAGRSKKETKSSLKAVEDMLETLQIT 295
>sp|Q15006|TTC35_HUMAN Tetratricopeptide repeat protein 35 OS=Homo sapiens
GN=TTC35 PE=1 SV=1
Length = 297
Score = 175 bits (442), Expect = 9e-043
Identities = 103/278 (37%), Positives = 163/278 (58%), Gaps = 11/278 (3%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE +++ G ++N+ S LG D W +YEQV IAA+D ++ C++ L+
Sbjct: 23 REENSRNSEQIVEVGEELINE--YASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L + EA +++A + Y +L+++P + KRK+A+ KAQGK A
Sbjct: 81 RQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EEL+++ P LY YA++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKDMAAPGLQ 873
T GGLENL +RKY+A + L ++ RALFG+ + S IA + K KD
Sbjct: 201 TQGGLENLELSRKYFAQALKL-NNRNMRALFGLYMSASHIASNPKASAKTKKDNMK--YA 257
Query: 874 SLAATALEKEY------KQKSPAKLNLLTSALRSLKMS 969
S AA+ + + Y K+++ L + L +L+++
Sbjct: 258 SWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQIT 295
>sp|Q5E993|TTC35_BOVIN Tetratricopeptide repeat protein 35 OS=Bos taurus
GN=TTC35 PE=2 SV=1
Length = 297
Score = 174 bits (440), Expect = 1e-042
Identities = 103/278 (37%), Positives = 163/278 (58%), Gaps = 11/278 (3%)
Frame = +1
Query: 154 RKLKVRRSEMVLKHGLSILNDPGKRSALGPDEWTLYEQVAIAAMDCQSLAVSQNCIKVLQ 333
R+ R SE +++ G ++++ S LG D W +YEQV IAA+D ++ C++ L+
Sbjct: 23 REENSRNSEQIVEVGEELISE--YASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELR 80
Query: 334 KKFPESKRVGKLEALLIEAKGMWEEAEKAYSILLEDNPLDQVIHKRKVAMAKAQGKPSLA 513
++FP S RV +L + EA +++A + Y +L+++P + KRK+A+ KAQGK A
Sbjct: 81 RQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEA 140
Query: 514 IEHLNKYLEVFMADHDAWRELAEIYVSLQMYKQAAFCYEELILSQPTLPLYHLAYADILY 693
I LN+YLE F+ D +AW ELAE+Y++ Y +AAFC EEL+++ P LY YA++ Y
Sbjct: 141 IRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPYNHLYCQQYAEVKY 200
Query: 694 TIGGLENLIAARKYYAATIDLTGGKSTRALFGICLCGSAIAQLSRGRNKEDKDMAAPGLQ 873
T GGLENL +RKY+A + L ++ RALFG+ + S IA + K KD
Sbjct: 201 TQGGLENLELSRKYFAQALKL-NNRNMRALFGLYMSASHIASNPKASAKTKKDNMK--YA 257
Query: 874 SLAATALEKEY------KQKSPAKLNLLTSALRSLKMS 969
S AA+ + K Y K+++ L + L +L+++
Sbjct: 258 SWAASQINKAYQFAGRSKKETKYSLKAVEDMLETLQIT 295
>sp|O60110|OCA3_SCHPO TPR repeat protein oca3 OS=Schizosaccharomyces pombe
GN=oca3 PE=4 SV=3
Length = 282
Score = 113 bits (281), Expect = 4e-024
Identities = 62/195 (31%), Positives = 106/195 (54%), Gaps = 3/195 (1%)
Frame = +1
Query: 250 WTLYEQVAIAAMDCQSLAVSQNCIKVLQKKFPESKRVGKLEALLIEAKGMWEEAEKAYSI 429
W +Y++V IAA+ +++ C L +F +S RV L + +EA ++A Y+
Sbjct: 37 WDVYQKVFIAALTTGETVLAKKCWNRLNDRFHKSPRVEGLYGMFLEATASEKDAMSYYNS 96
Query: 430 LLEDNPLDQVIHKRKVAMAKAQGKPSLAIEHLNKYLEVFMADHDAWRELAEIYVSLQMYK 609
L ++P VI+KRK+A+ ++ G+ I+ L YL+ F D +AW ELA+IYVS++ ++
Sbjct: 97 KLSEDPTHTVIYKRKLALLRSMGQTKECIQGLINYLDTFYNDLEAWAELADIYVSVEAFE 156
Query: 610 QAAFCYEELILSQPTLPLYHLAYADILYTI--GGLENLIAARKYYAATIDLTGGKSTRAL 783
A FCYEE++L QP P D+ + + N + K+Y ++++ +
Sbjct: 157 SAIFCYEEMVLLQPFEPRLFARLGDLYFVLAQSNATNYWFSLKHYCRSVEIC-EEYFHGW 215
Query: 784 FGICLCGSAIAQLSR 828
FGI C + +LSR
Sbjct: 216 FGISKCCQQLLELSR 230
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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