BLASTX 7.6.2
Query= UN19788 /QuerySize=865
(864 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BY50|SC11C_HUMAN Signal peptidase complex catalytic subunit... 211 8e-054
sp|Q5RC30|SC11C_PONAB Signal peptidase complex catalytic subunit... 211 8e-054
sp|Q9WTR7|SC11C_RAT Signal peptidase complex catalytic subunit S... 210 1e-053
sp|P13679|SC11C_CANFA Signal peptidase complex catalytic subunit... 210 2e-053
sp|Q9D8V7|SC11C_MOUSE Signal peptidase complex catalytic subunit... 210 2e-053
sp|P67810|SC11A_BOVIN Signal peptidase complex catalytic subunit... 205 4e-052
sp|P67811|SC11A_CANFA Signal peptidase complex catalytic subunit... 205 4e-052
sp|P67812|SC11A_HUMAN Signal peptidase complex catalytic subunit... 205 4e-052
sp|Q5R9C7|SC11A_PONAB Signal peptidase complex catalytic subunit... 205 4e-052
sp|Q9R0P6|SC11A_MOUSE Signal peptidase complex catalytic subunit... 203 2e-051
sp|P42667|SC11A_RAT Signal peptidase complex catalytic subunit S... 201 6e-051
sp|Q86JD4|SEC11_DICDI Signal peptidase complex catalytic subunit... 189 3e-047
sp|P0C7V7|SC11B_HUMAN Putative signal peptidase complex catalyti... 172 3e-042
>sp|Q9BY50|SC11C_HUMAN Signal peptidase complex catalytic subunit SEC11C OS=Homo
sapiens GN=SEC11C PE=1 SV=3
Length = 192
Score = 211 bits (535), Expect = 8e-054
Identities = 106/171 (61%), Positives = 131/171 (76%), Gaps = 2/171 (1%)
Frame = +3
Query: 123 IKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDILFL 302
+K + RQL Q ++ MIV+SAL+IWK L+ +TGSESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 303 -HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLLYAE 479
+ +DPIRAGEIVVF V+GRDIPIVHRVIKVHE+DN G++ LTKGDNN DDR LY E
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDN-GDIKFLTKGDNNEVDDRGLYKE 140
Query: 480 GQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
GQ WL + ++GRA GFLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|Q5RC30|SC11C_PONAB Signal peptidase complex catalytic subunit SEC11C
OS=Pongo abelii GN=SEC11C PE=2 SV=3
Length = 192
Score = 211 bits (535), Expect = 8e-054
Identities = 106/171 (61%), Positives = 131/171 (76%), Gaps = 2/171 (1%)
Frame = +3
Query: 123 IKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDILFL 302
+K + RQL Q ++ MIV+SAL+IWK L+ +TGSESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 303 -HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLLYAE 479
+ +DPIRAGEIVVF V+GRDIPIVHRVIKVHE+DN G++ LTKGDNN DDR LY E
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDN-GDIKFLTKGDNNEVDDRGLYKE 140
Query: 480 GQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
GQ WL + ++GRA GFLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|Q9WTR7|SC11C_RAT Signal peptidase complex catalytic subunit SEC11C OS=Rattus
norvegicus GN=Sec11c PE=2 SV=3
Length = 192
Score = 210 bits (533), Expect = 1e-053
Identities = 105/171 (61%), Positives = 131/171 (76%), Gaps = 2/171 (1%)
Frame = +3
Query: 123 IKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDILFL 302
++ + RQL Q ++ MIV+SAL+IWK L+ +TGSESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 303 -HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLLYAE 479
+ +DPIRAGEIVVF V+GRDIPIVHRVIKVHE+DN G++ LTKGDNN DDR LY E
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDN-GDIKFLTKGDNNEVDDRGLYKE 140
Query: 480 GQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
GQ WL + ++GRA GFLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALVAVMGAYVLLKRE 191
>sp|P13679|SC11C_CANFA Signal peptidase complex catalytic subunit SEC11C
OS=Canis familiaris GN=SEC11C PE=1 SV=3
Length = 192
Score = 210 bits (532), Expect = 2e-053
Identities = 105/171 (61%), Positives = 131/171 (76%), Gaps = 2/171 (1%)
Frame = +3
Query: 123 IKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDILFL 302
++ + RQL Q ++ MIV+SAL+IWK L+ +TGSESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 303 -HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLLYAE 479
+ +DPIRAGEIVVF V+GRDIPIVHRVIKVHE+DN G++ LTKGDNN DDR LY E
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDN-GDIKFLTKGDNNEVDDRGLYKE 140
Query: 480 GQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
GQ WL + ++GRA GFLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|Q9D8V7|SC11C_MOUSE Signal peptidase complex catalytic subunit SEC11C OS=Mus
musculus GN=Sec11c PE=2 SV=3
Length = 192
Score = 210 bits (532), Expect = 2e-053
Identities = 105/171 (61%), Positives = 131/171 (76%), Gaps = 2/171 (1%)
Frame = +3
Query: 123 IKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDILFL 302
++ + RQL Q ++ MIV+SAL+IWK L+ +TGSESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 303 -HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLLYAE 479
+ +DPIRAGEIVVF V+GRDIPIVHRVIKVHE+DN G++ LTKGDNN DDR LY E
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDN-GDIKFLTKGDNNEVDDRGLYKE 140
Query: 480 GQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
GQ WL + ++GRA GFLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|P67810|SC11A_BOVIN Signal peptidase complex catalytic subunit SEC11A OS=Bos
taurus GN=SEC11A PE=2 SV=1
Length = 179
Score = 205 bits (520), Expect = 4e-052
Identities = 99/174 (56%), Positives = 132/174 (75%), Gaps = 2/174 (1%)
Frame = +3
Query: 114 IDSIKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDI 293
+D ++ + RQL Q ++ GMIV+SAL+IWK LM +TGSESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 294 LFL-HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLL 470
LFL + +DPIR GEIVVF ++GR+IPIVHRV+K+HE+ N G + LTKGDNN DDR L
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQN-GHIKFLTKGDNNAVDDRGL 125
Query: 471 YAEGQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
Y +GQ WL + ++GRA GF+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|P67811|SC11A_CANFA Signal peptidase complex catalytic subunit SEC11A
OS=Canis familiaris GN=SEC11A PE=1 SV=1
Length = 179
Score = 205 bits (520), Expect = 4e-052
Identities = 99/174 (56%), Positives = 132/174 (75%), Gaps = 2/174 (1%)
Frame = +3
Query: 114 IDSIKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDI 293
+D ++ + RQL Q ++ GMIV+SAL+IWK LM +TGSESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 294 LFL-HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLL 470
LFL + +DPIR GEIVVF ++GR+IPIVHRV+K+HE+ N G + LTKGDNN DDR L
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQN-GHIKFLTKGDNNAVDDRGL 125
Query: 471 YAEGQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
Y +GQ WL + ++GRA GF+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|P67812|SC11A_HUMAN Signal peptidase complex catalytic subunit SEC11A OS=Homo
sapiens GN=SEC11A PE=1 SV=1
Length = 179
Score = 205 bits (520), Expect = 4e-052
Identities = 99/174 (56%), Positives = 132/174 (75%), Gaps = 2/174 (1%)
Frame = +3
Query: 114 IDSIKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDI 293
+D ++ + RQL Q ++ GMIV+SAL+IWK LM +TGSESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 294 LFL-HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLL 470
LFL + +DPIR GEIVVF ++GR+IPIVHRV+K+HE+ N G + LTKGDNN DDR L
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQN-GHIKFLTKGDNNAVDDRGL 125
Query: 471 YAEGQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
Y +GQ WL + ++GRA GF+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|Q5R9C7|SC11A_PONAB Signal peptidase complex catalytic subunit SEC11A
OS=Pongo abelii GN=SEC11A PE=2 SV=1
Length = 179
Score = 205 bits (520), Expect = 4e-052
Identities = 99/174 (56%), Positives = 132/174 (75%), Gaps = 2/174 (1%)
Frame = +3
Query: 114 IDSIKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDI 293
+D ++ + RQL Q ++ GMIV+SAL+IWK LM +TGSESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 294 LFL-HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLL 470
LFL + +DPIR GEIVVF ++GR+IPIVHRV+K+HE+ N G + LTKGDNN DDR L
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQN-GHIKFLTKGDNNAVDDRGL 125
Query: 471 YAEGQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
Y +GQ WL + ++GRA GF+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|Q9R0P6|SC11A_MOUSE Signal peptidase complex catalytic subunit SEC11A OS=Mus
musculus GN=Sec11a PE=2 SV=1
Length = 179
Score = 203 bits (515), Expect = 2e-051
Identities = 98/174 (56%), Positives = 132/174 (75%), Gaps = 2/174 (1%)
Frame = +3
Query: 114 IDSIKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDI 293
+D ++ + RQL Q ++ GMIV+SAL+IWK LM +TGSESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 294 LFL-HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLL 470
LFL + +DPIR GEIVVF ++GR+IPIVHRV+K+HE+ + G + LTKGDNN DDR L
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQD-GHIKFLTKGDNNAVDDRGL 125
Query: 471 YAEGQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
Y +GQ WL + ++GRA GF+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|P42667|SC11A_RAT Signal peptidase complex catalytic subunit SEC11A OS=Rattus
norvegicus GN=Sec11a PE=2 SV=1
Length = 179
Score = 201 bits (510), Expect = 6e-051
Identities = 97/174 (55%), Positives = 131/174 (75%), Gaps = 2/174 (1%)
Frame = +3
Query: 114 IDSIKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDI 293
+D ++ + RQL Q ++ GMIV+SAL+IWK LM +TGSESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMLITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 294 LFL-HMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLL 470
LFL + +DPIR GEIVVF ++GR+IPIVHRV+K+HE+ + G + LTKGDNN DDR L
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQD-GHIKFLTKGDNNAVDDRGL 125
Query: 471 YAEGQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
Y +GQ WL + ++GRA GF+PY+G VTI+M + P Y ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFSYAVLFLLGLFVLVHRE 179
>sp|Q86JD4|SEC11_DICDI Signal peptidase complex catalytic subunit sec11
OS=Dictyostelium discoideum GN=sec11 PE=3 SV=1
Length = 179
Score = 189 bits (478), Expect = 3e-047
Identities = 92/180 (51%), Positives = 130/180 (72%), Gaps = 1/180 (0%)
Frame = +3
Query: 93 MGYIGETIDSIKSIQIRQLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEP 272
M I I+ SI Q+ Q ++ G+IV +AL+IWK LM +GSESP+VVVLSGSM P
Sbjct: 1 MNDIISKINPFSSIPKHQIAQQIVNFGLIVATALMIWKGLMIFSGSESPIVVVLSGSMIP 60
Query: 273 GFKRGDILFLHMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNY 452
F RGD+L+L+M P R GEIVVF ++G++IPIVHR++++HE+++ G D+ TKGDNN
Sbjct: 61 AFFRGDLLYLNMEDGPFRVGEIVVFKIEGKEIPIVHRILQIHEKED-GLYDIRTKGDNNN 119
Query: 453 GDDRLLYAEGQQWLHRHHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
DD LY+ GQ+WL R HI+GRA GFLP VG VTI+M + P +K+ L+ L + V+++++
Sbjct: 120 VDDVGLYSPGQRWLSRDHIIGRAKGFLPSVGMVTIVMHDYPQLKFFLVFVLAVFVLSTRE 179
>sp|P0C7V7|SC11B_HUMAN Putative signal peptidase complex catalytic subunit
SEC11B OS=Homo sapiens GN=SEC11B PE=5 SV=1
Length = 166
Score = 172 bits (435), Expect = 3e-042
Identities = 88/164 (53%), Positives = 118/164 (71%), Gaps = 3/164 (1%)
Frame = +3
Query: 144 QLLTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDILFL-HMSKDP 320
+L Q ++ GMIV+SAL+IWK LM +TGSESP +V+LSGSMEP F RG +LFL + +DP
Sbjct: 5 RLYYQVLNFGMIVSSALMIWKGLMVITGSESP-IVLLSGSMEPAFHRGYLLFLTNRVEDP 63
Query: 321 IRAGEIVVFNVDGRDIPIVHRVIKVHERDNTGEVDVLTKGDNNYGDDRLLYAEGQQWLHR 500
IR GEI V ++GR IPIVHRV+K+HE+ N G + LTKGDNN DDR LY + Q WL +
Sbjct: 64 IRVGEIAVLRIEGRKIPIVHRVLKIHEKQN-GHIKFLTKGDNNAVDDRGLYKQDQHWLEK 122
Query: 501 HHIMGRAVGFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 632
++GRA GF+PY+G T +M + P KY ++ LGL V+ ++
Sbjct: 123 KDVVGRARGFVPYIGIGTSLMNDYPKHKYEVLFLLGLFVLVHRE 166
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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