BLASTX 7.6.2
Query= UN19898 /QuerySize=1475
(1474 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P52901|ODPA1_ARATH Pyruvate dehydrogenase E1 component subuni... 740 8e-213
sp|P52902|ODPA_PEA Pyruvate dehydrogenase E1 component subunit a... 670 1e-191
sp|Q8H1Y0|ODPA2_ARATH Pyruvate dehydrogenase E1 component subuni... 661 6e-189
sp|P52903|ODPA_SOLTU Pyruvate dehydrogenase E1 component subunit... 649 2e-185
sp|Q54C70|ODPA_DICDI Pyruvate dehydrogenase E1 component subunit... 403 2e-111
sp|P16387|ODPA_YEAST Pyruvate dehydrogenase E1 component subunit... 374 9e-103
sp|O13366|ODPA_KLULA Pyruvate dehydrogenase E1 component subunit... 369 3e-101
sp|Q10489|ODPA_SCHPO Pyruvate dehydrogenase E1 component subunit... 367 1e-100
sp|P52900|ODPA_SMIMA Pyruvate dehydrogenase E1 component subunit... 361 8e-099
sp|A7MB35|ODPA_BOVIN Pyruvate dehydrogenase E1 component subunit... 361 1e-098
sp|P52899|ODPA_CAEEL Probable pyruvate dehydrogenase E1 componen... 359 3e-098
sp|P29804|ODPA_PIG Pyruvate dehydrogenase E1 component subunit a... 359 4e-098
sp|P26284|ODPA_RAT Pyruvate dehydrogenase E1 component subunit a... 359 5e-098
sp|P08559|ODPA_HUMAN Pyruvate dehydrogenase E1 component subunit... 358 6e-098
sp|P29803|ODPAT_HUMAN Pyruvate dehydrogenase E1 component subuni... 356 2e-097
sp|P35486|ODPA_MOUSE Pyruvate dehydrogenase E1 component subunit... 356 2e-097
sp|A5A6L0|ODPA_PANTR Pyruvate dehydrogenase E1 component subunit... 356 4e-097
sp|Q5R490|ODPA_PONAB Pyruvate dehydrogenase E1 component subunit... 356 4e-097
sp|P35487|ODPAT_MOUSE Pyruvate dehydrogenase E1 component subuni... 351 8e-096
sp|P26267|ODPA_ASCSU Pyruvate dehydrogenase E1 component subunit... 339 4e-092
>sp|P52901|ODPA1_ARATH Pyruvate dehydrogenase E1 component subunit alpha-1,
mitochondrial OS=Arabidopsis thaliana GN=At1g59900 PE=1 SV=2
Length = 389
Score = 740 bits (1909), Expect = 8e-213
Identities = 361/385 (93%), Positives = 376/385 (97%)
Frame = +3
Query: 51 RLTSRSTLISHPLSAAFNRFISTDTTPITIETSLPFTAHLCDPPSRSVESSTQELLSFFR 230
RL+SRS +I+ P SAAF+R ISTDTTPITIETSLPFTAHLCDPPSRSVESS+QELL FFR
Sbjct: 5 RLSSRSNIITRPFSAAFSRLISTDTTPITIETSLPFTAHLCDPPSRSVESSSQELLDFFR 64
Query: 231 TMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLG 410
TMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLG
Sbjct: 65 TMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLG 124
Query: 411 RGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGIVGAQVPLGCGIAFAQKYG 590
RGGSL+EVF+ELMGR+ GCS+GKGGSMHFYKK+SSFYGGHGIVGAQVPLGCGIAFAQKY
Sbjct: 125 RGGSLHEVFSELMGRQAGCSKGKGGSMHFYKKESSFYGGHGIVGAQVPLGCGIAFAQKYN 184
Query: 591 KEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNHYGMGTAEWRAAKSPSYYK 770
KEEAVTFA+YGDGAANQGQLFEALNISALWDLP+ILVCENNHYGMGTAEWRAAKSPSYYK
Sbjct: 185 KEEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMGTAEWRAAKSPSYYK 244
Query: 771 RGDYVPGLKVDGMDAFAVKQACKFAKEHALKNGPIILEMDTYRYHGHSMSDPGSTYRTRD 950
RGDYVPGLKVDGMDAFAVKQACKFAK+HAL+ GPIILEMDTYRYHGHSMSDPGSTYRTRD
Sbjct: 245 RGDYVPGLKVDGMDAFAVKQACKFAKQHALEKGPIILEMDTYRYHGHSMSDPGSTYRTRD 304
Query: 951 EISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSELF 1130
EISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSELF
Sbjct: 305 EISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSELF 364
Query: 1131 TNVYVKGFGTESFGADRKEVKAALP 1205
TNVYVKGFGTESFG DRKEVKA+LP
Sbjct: 365 TNVYVKGFGTESFGPDRKEVKASLP 389
>sp|P52902|ODPA_PEA Pyruvate dehydrogenase E1 component subunit alpha,
mitochondrial OS=Pisum sativum PE=2 SV=1
Length = 397
Score = 670 bits (1727), Expect = 1e-191
Identities = 329/397 (82%), Positives = 360/397 (90%), Gaps = 7/397 (1%)
Frame = +3
Query: 36 MALSRRLTSRSTL----ISHPLSAAF--NRFISTDTT-PITIETSLPFTAHLCDPPSRSV 194
MALSR +S S+ + +P SAAF NR IS+DTT +TIETSLPFTAH CDPPSRSV
Sbjct: 1 MALSRLSSSSSSSNGSNLFNPFSAAFTLNRPISSDTTATLTIETSLPFTAHNCDPPSRSV 60
Query: 195 ESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAI 374
+S ELLSFFRTMALMRRMEIAADSLYKA LIRGFCHLYDGQEAVA+GMEA TKKD I
Sbjct: 61 TTSPSELLSFFRTMALMRRMEIAADSLYKANLIRGFCHLYDGQEAVAVGMEAGTTKKDCI 120
Query: 375 ITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGIVGAQVP 554
ITAYRDHC FLGRGG+L V+AELMGRRDGCS+GKGGSMHFYKKDS FYGGHGIVGAQVP
Sbjct: 121 ITAYRDHCTFLGRGGTLLRVYAELMGRRDGCSKGKGGSMHFYKKDSGFYGGHGIVGAQVP 180
Query: 555 LGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNHYGMGTA 734
LGCG+AF QKY K+E+VTFA+YGDGAANQGQLFEALNISALWDLP+ILVCENNHYGMGTA
Sbjct: 181 LGCGLAFGQKYLKDESVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMGTA 240
Query: 735 EWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALKNGPIILEMDTYRYHGHS 914
WR+AKSP+Y+KRGDYVPGLKVDGMDA AVKQACKFAKEHALKNGPIILEMDTYRYHGHS
Sbjct: 241 TWRSAKSPAYFKRGDYVPGLKVDGMDALAVKQACKFAKEHALKNGPIILEMDTYRYHGHS 300
Query: 915 MSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKA 1094
MSDPGSTYRTRDEISGVRQERDPIER++KL+LSHD+ATEKELKD EKE+RKEVD+AIAKA
Sbjct: 301 MSDPGSTYRTRDEISGVRQERDPIERVRKLLLSHDIATEKELKDTEKEVRKEVDEAIAKA 360
Query: 1095 KDCPMPEPSELFTNVYVKGFGTESFGADRKEVKAALP 1205
KD PMP+PS+LF+NVYVKG+G E+FG DRKEV+ LP
Sbjct: 361 KDSPMPDPSDLFSNVYVKGYGVEAFGVDRKEVRVTLP 397
>sp|Q8H1Y0|ODPA2_ARATH Pyruvate dehydrogenase E1 component subunit alpha-2,
mitochondrial OS=Arabidopsis thaliana GN=IAR4 PE=1 SV=2
Length = 393
Score = 661 bits (1703), Expect = 6e-189
Identities = 317/394 (80%), Positives = 360/394 (91%), Gaps = 5/394 (1%)
Frame = +3
Query: 36 MALSRRLTSRSTLISHP----LSAAFNRFISTDTTPITIETSLPFTAHLCDPPSRSVESS 203
MALS RL+SRS P L ++ R +STD++PITIET++PFT+HLC+ PSRSVE+S
Sbjct: 1 MALS-RLSSRSNTFLKPAITALPSSIRRHVSTDSSPITIETAVPFTSHLCESPSRSVETS 59
Query: 204 TQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAIITA 383
++E+L+FFR MA MRRMEIAADSLYKAKLIRGFCHLYDGQEA+A+GMEAAITKKDAIIT+
Sbjct: 60 SEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEALAVGMEAAITKKDAIITS 119
Query: 384 YRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGIVGAQVPLGC 563
YRDHC F+GRGG L + F+ELMGR+ GCS GKGGSMHFYKKD+SFYGGHGIVGAQ+PLGC
Sbjct: 120 YRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYKKDASFYGGHGIVGAQIPLGC 179
Query: 564 GIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNHYGMGTAEWR 743
G+AFAQKY K+EAVTFA+YGDGAANQGQLFEALNISALWDLP+ILVCENNHYGMGTA WR
Sbjct: 180 GLAFAQKYNKDEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMGTATWR 239
Query: 744 AAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALKNGPIILEMDTYRYHGHSMSD 923
+AKSP+Y+KRGDYVPGLKVDGMDA AVKQACKFAKEHALKNGPIILEMDTYRYHGHSMSD
Sbjct: 240 SAKSPAYFKRGDYVPGLKVDGMDALAVKQACKFAKEHALKNGPIILEMDTYRYHGHSMSD 299
Query: 924 PGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKAKDC 1103
PGSTYRTRDEISGVRQ RDPIER++KL+L+HD+ATEKELKDMEKEIRKEVDDA+A+AK+
Sbjct: 300 PGSTYRTRDEISGVRQVRDPIERVRKLLLTHDIATEKELKDMEKEIRKEVDDAVAQAKES 359
Query: 1104 PMPEPSELFTNVYVKGFGTESFGADRKEVKAALP 1205
P+P+ SELFTN+YVK G ESFGADRKE+K LP
Sbjct: 360 PIPDASELFTNMYVKDCGVESFGADRKELKVTLP 393
>sp|P52903|ODPA_SOLTU Pyruvate dehydrogenase E1 component subunit alpha,
mitochondrial OS=Solanum tuberosum PE=1 SV=1
Length = 391
Score = 649 bits (1673), Expect = 2e-185
Identities = 320/394 (81%), Positives = 353/394 (89%), Gaps = 7/394 (1%)
Frame = +3
Query: 36 MALSRRLTSRS-TLISHPLSAAF---NRFISTDTTPITIETSLPFTAHLCDPPSRSVESS 203
MALS TSR+ I PLSAA R S T IT+ETSLPFT+H DPPSRSVE+S
Sbjct: 1 MALS---TSRAINHIMKPLSAAVCATRRLSSDSTATITVETSLPFTSHNIDPPSRSVETS 57
Query: 204 TQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAITKKDAIITA 383
+EL++FF+ M MRRMEIAADSLYKAKLIRGFCHLYDGQEAVA+GMEAAITKKD IITA
Sbjct: 58 PKELMTFFKDMTEMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAVGMEAAITKKDCIITA 117
Query: 384 YRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGIVGAQVPLGC 563
YRDHCIFLGRGG+L E FAELMGRRDGCSRGKGGSMHFYKK+S FYGGHGIVGAQVPLG
Sbjct: 118 YRDHCIFLGRGGTLVEAFAELMGRRDGCSRGKGGSMHFYKKESGFYGGHGIVGAQVPLGI 177
Query: 564 GIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNHYGMGTAEWR 743
G+AFAQKY KE+ VTFAMYGDGAANQGQLFEALN++ALWDLP+ILVCENNHYGMGTAEWR
Sbjct: 178 GLAFAQKYKKEDYVTFAMYGDGAANQGQLFEALNMAALWDLPAILVCENNHYGMGTAEWR 237
Query: 744 AAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALKNGPIILEMDTYRYHGHSMSD 923
AAKSP+YYKRGDYVPGL+VDGMD FAVKQAC FAK+HALKNGPIILEMDTYRYHGHSMSD
Sbjct: 238 AAKSPAYYKRGDYVPGLRVDGMDVFAVKQACTFAKQHALKNGPIILEMDTYRYHGHSMSD 297
Query: 924 PGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVDDAIAKAKDC 1103
PGSTYRTRDEISGVRQERDP+ERI+ L+L+H++ATE ELKD+EKE RK VD+AIAKAK+
Sbjct: 298 PGSTYRTRDEISGVRQERDPVERIRSLILAHNIATEAELKDIEKENRKVVDEAIAKAKES 357
Query: 1104 PMPEPSELFTNVYVKGFGTESFGADRKEVKAALP 1205
PMP+PSELFTNVYVKGFG E++GADRKE++A LP
Sbjct: 358 PMPDPSELFTNVYVKGFGVEAYGADRKELRATLP 391
>sp|Q54C70|ODPA_DICDI Pyruvate dehydrogenase E1 component subunit alpha,
mitochondrial OS=Dictyostelium discoideum GN=pdhA PE=1 SV=1
Length = 377
Score = 403 bits (1035), Expect = 2e-111
Identities = 200/329 (60%), Positives = 245/329 (74%), Gaps = 3/329 (0%)
Frame = +3
Query: 165 HLCDPPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGM 344
+LCD PS S ++ EL+SFF M+ RR+E D LYK KLIRGFCHLY GQEAV G+
Sbjct: 36 YLCDGPSDSTVTNKDELISFFTEMSRFRRLETVCDGLYKKKLIRGFCHLYTGQEAVCAGL 95
Query: 345 EAAITKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYG 524
E+AITK D IITAYRDH L RG + E+FAEL+ + GCS+GKGGSMH + K +FYG
Sbjct: 96 ESAITKDDHIITAYRDHTYMLSRGATPEEIFAELLMKETGCSKGKGGSMHMFTK--NFYG 153
Query: 525 GHGIVGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVC 704
G+GIVGAQ PLG GIAFAQKY K V AMYGDGAANQGQLFEA N+++LW LP I +C
Sbjct: 154 GNGIVGAQCPLGAGIAFAQKYNKTGNVCLAMYGDGAANQGQLFEAFNMASLWKLPVIFIC 213
Query: 705 ENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHA-LKNGPIIL 881
ENN YGMGT++ R+ +Y RG YV GLKVDGMD FAVK+A K+A E NGPIIL
Sbjct: 214 ENNKYGMGTSQKRSTAGHDFYTRGHYVAGLKVDGMDVFAVKEAGKYAAEWCRAGNGPIIL 273
Query: 882 EMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEI 1061
EMDTYRY GHSMSDPG TYRTR+E++ VRQ RDPIE I++++L + +ATE +L +E+ +
Sbjct: 274 EMDTYRYVGHSMSDPGITYRTREEVNHVRQTRDPIENIRQIILDNKIATEDQLAAIEETV 333
Query: 1062 RKEVDDAIAKAKDCPMPEPSELFTNVYVK 1148
R E++ A KA P+P+ ELFTNVY++
Sbjct: 334 RDEMEKASEKAIAAPLPQARELFTNVYLQ 362
>sp|P16387|ODPA_YEAST Pyruvate dehydrogenase E1 component subunit alpha,
mitochondrial OS=Saccharomyces cerevisiae GN=PDA1 PE=1 SV=2
Length = 420
Score = 374 bits (960), Expect = 9e-103
Identities = 192/348 (55%), Positives = 245/348 (70%), Gaps = 8/348 (2%)
Frame = +3
Query: 135 TIETSLP---FTAHLCDPPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFC 305
T++ LP F +++ +PP S E+S LL ++ M ++RRME+A D+LYKAK IRGFC
Sbjct: 52 TVQIELPESSFESYMLEPPDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFC 111
Query: 306 HLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGG 485
HL GQEA+A+G+E AITK D+IIT+YR H RG S+ V AELMGRR G S GKGG
Sbjct: 112 HLSVGQEAIAVGIENAITKLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGG 171
Query: 486 SMHFYKKDSSFYGGHGIVGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALN 665
SMH Y FYGG+GIVGAQVPLG G+AFA +Y E+A +F +YGDGA+NQGQ+FE+ N
Sbjct: 172 SMHLYA--PGFYGGNGIVGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFN 229
Query: 666 ISALWDLPSILVCENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFA 845
++ LW+LP + CENN YGMGTA R++ Y+KRG Y+PGLKV+GMD AV QA KFA
Sbjct: 230 MAKLWNLPVVFCCENNKYGMGTAASRSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFA 289
Query: 846 KEHALK-NGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDL 1022
K+ L GP++LE +TYRY GHSMSDPG+TYRTRDEI +R + DPI +K ++ +
Sbjct: 290 KDWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGI 349
Query: 1023 ATEKELKDMEKEIRKEVDDAIAKAKDCPMPEP--SELFTNVYVKGFGT 1160
ATE E+K +K RK VD+ + A P PE S LF +VYVKG T
Sbjct: 350 ATEAEVKAYDKSARKYVDEQVELADAAPPPEAKLSILFEDVYVKGTET 397
>sp|O13366|ODPA_KLULA Pyruvate dehydrogenase E1 component subunit alpha,
mitochondrial OS=Kluyveromyces lactis GN=PDA1 PE=3 SV=2
Length = 412
Score = 369 bits (947), Expect = 3e-101
Identities = 190/343 (55%), Positives = 242/343 (70%), Gaps = 7/343 (2%)
Frame = +3
Query: 141 ETSLPFTAHLCDPPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDG 320
ETS F +L D P S +++ LL ++ M ++RRME+A D+LYKAK IRGFCH G
Sbjct: 51 ETS--FEGYLLDVPELSYQTTKSNLLQMYKDMIIVRRMEMACDALYKAKKIRGFCHSSVG 108
Query: 321 QEAVAIGMEAAITKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFY 500
QEA+A+G+E AITK+D +IT+YR H RG ++ V AELMGRR G S GKGGSMH Y
Sbjct: 109 QEAIAVGIENAITKRDTVITSYRCHGFTYMRGAAVQAVLAELMGRRTGVSFGKGGSMHLY 168
Query: 501 KKDSSFYGGHGIVGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALW 680
FYGG+GIVGAQVPLG G+AFA +Y E+A +FA+YGDGA+NQGQ+FE+ N++ LW
Sbjct: 169 A--PGFYGGNGIVGAQVPLGAGLAFAHQYKHEDACSFALYGDGASNQGQVFESFNMAKLW 226
Query: 681 DLPSILVCENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHAL 860
+LP++ CENN YGMGTA R++ Y+KRG Y+PGLKV+GMD AV QA KFAK+ +
Sbjct: 227 NLPAVFCCENNKYGMGTAAARSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWTV 286
Query: 861 K-NGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKE 1037
NGPI+LE +TYRY GHSMSDPG+TYRTRDEI +R + DPI +K +L +ATE E
Sbjct: 287 SGNGPIVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLLELGIATEDE 346
Query: 1038 LKDMEKEIRKEVDDAIAKAKDCPMPEP--SELFTNVYVKGFGT 1160
+K +K RK VD+ + A P PE S LF +VYV G T
Sbjct: 347 IKAYDKAARKYVDEQVELADAAPAPEAKMSILFEDVYVPGSET 389
>sp|Q10489|ODPA_SCHPO Pyruvate dehydrogenase E1 component subunit alpha,
mitochondrial OS=Schizosaccharomyces pombe GN=pda1 PE=1 SV=1
Length = 409
Score = 367 bits (941), Expect = 1e-100
Identities = 185/344 (53%), Positives = 244/344 (70%), Gaps = 6/344 (1%)
Frame = +3
Query: 129 PITIETSLPFTAHLCDPPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCH 308
P+ ++ S+ F + D PS +E + ELL + M +RR+E+A D+LYKAK IRGFCH
Sbjct: 51 PVKLDDSV-FEGYKIDVPSTEIEVTKGELLGLYEKMVTIRRLELACDALYKAKKIRGFCH 109
Query: 309 LYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGS 488
L GQEAVA G+E AIT D+IIT+YR H RG S+ + ELMGR+ G S+GKGGS
Sbjct: 110 LSIGQEAVAAGIEGAITLDDSIITSYRCHGFAYTRGLSIRSIIGELMGRQCGASKGKGGS 169
Query: 489 MHFYKKDSSFYGGHGIVGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNI 668
MH + K +FYGG+GIVGAQ+PLG GI FAQKY ++ TFA+YGDGA+NQGQ FEA N+
Sbjct: 170 MHIFAK--NFYGGNGIVGAQIPLGAGIGFAQKYLEKPTTTFALYGDGASNQGQAFEAFNM 227
Query: 669 SALWDLPSILVCENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAK 848
+ LW LP I CENN YGMGT+ R++ +YKRG Y+PGL V+GMD AV QA KFAK
Sbjct: 228 AKLWGLPVIFACENNKYGMGTSAERSSAMTEFYKRGQYIPGLLVNGMDVLAVLQASKFAK 287
Query: 849 EHALKNG-PIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLA 1025
++ ++N P+++E TYRY GHSMSDPG+TYR+R+E+ VR RDPIE +KK ++ +A
Sbjct: 288 KYTVENSQPLLMEFVTYRYGGHSMSDPGTTYRSREEVQKVRAARDPIEGLKKHIMEWGVA 347
Query: 1026 TEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSE--LFTNVYVKG 1151
ELK++EK IR VD+ + A++ P P+P E LF++VYV G
Sbjct: 348 NANELKNIEKRIRGMVDEEVRIAEESPFPDPIEESLFSDVYVAG 391
>sp|P52900|ODPA_SMIMA Pyruvate dehydrogenase E1 component subunit alpha,
mitochondrial (Fragment) OS=Sminthopsis macroura GN=PDHA PE=2 SV=1
Length = 363
Score = 361 bits (926), Expect = 8e-099
Identities = 179/336 (53%), Positives = 240/336 (71%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP+ +V + +E L +++ M +RRME+ AD LYK K+IRGFCHLYDGQEA +G+EA I
Sbjct: 23 PPTTAV-LTREEGLKYYKIMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCMGLEAGI 81
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG + E+ AEL GRR GC++GKGGSMH Y K +FYGG+GI
Sbjct: 82 NPTDHVITAYRAHGFTYTRGLPVREILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGI 139
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY +++ + +YGDGAANQGQ+FEA N++ALW LP I +CENN
Sbjct: 140 VGAQVPLGVGIALACKYNEKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNR 199
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PG+ VDGMD V++A KFA + GP+++E+ T
Sbjct: 200 YGMGTSVERAAASTDYYKRGDFIPGIMVDGMDVLCVREATKFAAAYCRSGKGPMLMELQT 259
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR + DPI +K +++++LA+ +ELK+++ E+RKE+
Sbjct: 260 YRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNNNLASIEELKEIDVEVRKEI 319
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y + E GA++
Sbjct: 320 EDAAQFATADPEPPLEELGYHIYSRDPPFEVRGANQ 355
>sp|A7MB35|ODPA_BOVIN Pyruvate dehydrogenase E1 component subunit alpha, somatic
form, mitochondrial OS=Bos taurus GN=PDHA1 PE=2 SV=1
Length = 390
Score = 361 bits (925), Expect = 1e-098
Identities = 182/336 (54%), Positives = 237/336 (70%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + ++ L ++R M +RRME+ AD LYK K+IRGFCHL DGQEA +G+EA I
Sbjct: 50 PPVTTV-LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGI 108
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG S+ E+ AEL GRR GC++GKGGSMH Y K +FYGG+GI
Sbjct: 109 NPTDHLITAYRAHGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGI 166
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY ++ V +YGDGAANQGQ+FEA N++ALW LP I +CENN
Sbjct: 167 VGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNR 226
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PGL+VDGMD V++A KFA + GPI++E+ T
Sbjct: 227 YGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQT 286
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR + DPI +K +++ +LA+ +ELK+++ E+RKE+
Sbjct: 287 YRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEI 346
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y E GA++
Sbjct: 347 EDAAQFATADPEPPLEELGYHIYCNDPPFEVRGANQ 382
>sp|P52899|ODPA_CAEEL Probable pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial OS=Caenorhabditis elegans GN=T05H10.6 PE=3 SV=1
Length = 397
Score = 359 bits (921), Expect = 3e-098
Identities = 185/342 (54%), Positives = 242/342 (70%), Gaps = 5/342 (1%)
Frame = +3
Query: 123 TTPITIETSLPFTAHLCD-PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRG 299
+T ++ T P H D P+ SV + ++ L ++R M ++RRME AA +LYK K IRG
Sbjct: 25 STEVSFHTK-PCKLHKLDNGPNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRG 83
Query: 300 FCHLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGK 479
FCHLY GQEA A+GM+AA+T+ DA+ITAYR H G ++ EV AEL GR G GK
Sbjct: 84 FCHLYSGQEACAVGMKAAMTEGDAVITAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGK 143
Query: 480 GGSMHFYKKDSSFYGGHGIVGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEA 659
GGSMH Y K +FYGG+GIVGAQ PLG G+A A KY +++ V +YGDGAANQGQLFEA
Sbjct: 144 GGSMHMYTK--NFYGGNGIVGAQQPLGAGVALAMKYREQKNVCVTLYGDGAANQGQLFEA 201
Query: 660 LNISALWDLPSILVCENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACK 839
N++ LWDLP + VCENN +GMGT R++ S YY RGDYVPG+ VDGMD AV++A K
Sbjct: 202 TNMAKLWDLPVLFVCENNGFGMGTTAERSSASTEYYTRGDYVPGIWVDGMDILAVREATK 261
Query: 840 FAKEHA-LKNGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSH 1016
+AKE+ GP+++EM TYRYHGHSMSDPG++YRTR+EI VR+ RDPI K +++
Sbjct: 262 WAKEYCDSGKGPLMMEMATYRYHGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITS 321
Query: 1017 DLATEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSELFTNVY 1142
LATE+ELK ++KE+RKEVD+A+ A + P L+ ++Y
Sbjct: 322 SLATEEELKAIDKEVRKEVDEALKIATSDGVLPPEALYADIY 363
>sp|P29804|ODPA_PIG Pyruvate dehydrogenase E1 component subunit alpha, somatic
form, mitochondrial (Fragment) OS=Sus scrofa GN=PDHA1 PE=1 SV=1
Length = 389
Score = 359 bits (920), Expect = 4e-098
Identities = 180/336 (53%), Positives = 236/336 (70%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + ++ L ++R M +RRME+ AD LYK K+IRGFCHL DGQEA +G+EA I
Sbjct: 49 PPVTTV-LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGI 107
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG S+ E+ AEL GRR GC +GKGGSMH Y K +FYGG+GI
Sbjct: 108 NPTDHLITAYRAHGFTFTRGLSVREILAELTGRRGGCGKGKGGSMHMYAK--NFYGGNGI 165
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY ++ V +YGDGAANQGQ+FEA N++ALW LP + +CENN
Sbjct: 166 VGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFICENNR 225
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PGL+VDGMD V++A +FA + GPI++E+ T
Sbjct: 226 YGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQT 285
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR + DPI +K +++ +LA+ +ELK+++ E+RKE+
Sbjct: 286 YRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEI 345
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y E GA++
Sbjct: 346 EDAAQFATADPEPPLEELGYHIYCNDPPFEVRGANQ 381
>sp|P26284|ODPA_RAT Pyruvate dehydrogenase E1 component subunit alpha, somatic
form, mitochondrial OS=Rattus norvegicus GN=Pdha1 PE=1 SV=2
Length = 390
Score = 359 bits (919), Expect = 5e-098
Identities = 180/336 (53%), Positives = 236/336 (70%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + ++ L ++R M +RRME+ AD LYK K+IRGFCHL DGQEA +G+EA I
Sbjct: 50 PPVTTV-LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGI 108
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG ++ + AEL GRR GC++GKGGSMH Y K +FYGG+GI
Sbjct: 109 NPTDHLITAYRAHGFTFNRGHAVRAILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGI 166
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY ++ V +YGDGAANQGQ+FEA N++ALW LP I +CENN
Sbjct: 167 VGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNR 226
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PGL+VDGMD V++A KFA + GPI++E+ T
Sbjct: 227 YGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQT 286
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR + DPI +K +++ +LA+ +ELK+++ E+RKE+
Sbjct: 287 YRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEI 346
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y E GA++
Sbjct: 347 EDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQ 382
>sp|P08559|ODPA_HUMAN Pyruvate dehydrogenase E1 component subunit alpha, somatic
form, mitochondrial OS=Homo sapiens GN=PDHA1 PE=1 SV=3
Length = 390
Score = 358 bits (918), Expect = 6e-098
Identities = 180/336 (53%), Positives = 237/336 (70%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + ++ L ++R M +RRME+ AD LYK K+IRGFCHL DGQEA +G+EA I
Sbjct: 50 PPVTTV-LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGI 108
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG S+ E+ AEL GR+ GC++GKGGSMH Y K +FYGG+GI
Sbjct: 109 NPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGI 166
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY ++ V +YGDGAANQGQ+FEA N++ALW LP I +CENN
Sbjct: 167 VGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNR 226
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PGL+VDGMD V++A +FA + GPI++E+ T
Sbjct: 227 YGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQT 286
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR + DPI +K +++ +LA+ +ELK+++ E+RKE+
Sbjct: 287 YRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEI 346
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y E GA++
Sbjct: 347 EDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQ 382
>sp|P29803|ODPAT_HUMAN Pyruvate dehydrogenase E1 component subunit alpha,
testis-specific form, mitochondrial OS=Homo sapiens GN=PDHA2 PE=1 SV=1
Length = 388
Score = 356 bits (913), Expect = 2e-097
Identities = 180/335 (53%), Positives = 231/335 (68%), Gaps = 4/335 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + E L ++R M +RRME+ AD LYK K IRGFCHL DGQEA +G+EA I
Sbjct: 48 PPVTTV-LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGI 106
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +IT+YR H + RG S+ + AEL GRR GC++GKGGSMH Y K +FYGG+GI
Sbjct: 107 NPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGI 164
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQ PLG GIA A KY + + +YGDGAANQGQ+ EA N++ALW LP + +CENN
Sbjct: 165 VGAQGPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNL 224
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA SP YYKRG+++PGLKVDGMD V++A KFA + GPI++E+ T
Sbjct: 225 YGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQT 284
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR +RDPI ++ +++ LAT +ELK++ E+RKE+
Sbjct: 285 YRYHGHSMSDPGVSYRTREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEI 344
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGAD 1178
DDA A P P EL ++Y E GA+
Sbjct: 345 DDAAQFATTDPEPHLEELGHHIYSSDSSFEVRGAN 379
>sp|P35486|ODPA_MOUSE Pyruvate dehydrogenase E1 component subunit alpha, somatic
form, mitochondrial OS=Mus musculus GN=Pdha1 PE=1 SV=1
Length = 390
Score = 356 bits (913), Expect = 2e-097
Identities = 180/336 (53%), Positives = 235/336 (69%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + ++ L ++R M +RRME+ AD LYK K+IRGFCHL DGQEA +G+EA I
Sbjct: 50 PPVTTV-LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGI 108
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG + + AEL GRR GC++GKGGSMH Y K +FYGG+GI
Sbjct: 109 NPTDHLITAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGI 166
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY ++ V +YGDGAANQGQ+FEA N++ALW LP I +CENN
Sbjct: 167 VGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNR 226
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PGL+VDGMD V++A KFA + GPI++E+ T
Sbjct: 227 YGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQT 286
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR + DPI +K +++ +LA+ +ELK+++ E+RKE+
Sbjct: 287 YRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEI 346
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y E GA++
Sbjct: 347 EDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQ 382
>sp|A5A6L0|ODPA_PANTR Pyruvate dehydrogenase E1 component subunit alpha, somatic
form, mitochondrial OS=Pan troglodytes GN=PDHA1 PE=2 SV=1
Length = 390
Score = 356 bits (911), Expect = 4e-097
Identities = 179/336 (53%), Positives = 236/336 (70%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + ++ L ++R M +RRME+ AD LYK K+IRGFCHL DGQEA +G+EA I
Sbjct: 50 PPVTTV-LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGI 108
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG S+ E+ AEL GR+ GC++GKGGSMH Y K +FYGG+GI
Sbjct: 109 NPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGI 166
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY ++ V +YGDGAANQGQ+FEA N++ALW LP I +CENN
Sbjct: 167 VGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNR 226
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PGL+VDGMD V++A +FA + GPI++E+ T
Sbjct: 227 YGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQT 286
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMS PG +YRTR+EI VR + DPI +K +++ +LA+ +ELK+++ E+RKE+
Sbjct: 287 YRYHGHSMSGPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEI 346
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y E GA++
Sbjct: 347 EDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQ 382
>sp|Q5R490|ODPA_PONAB Pyruvate dehydrogenase E1 component subunit alpha, somatic
form, mitochondrial OS=Pongo abelii GN=PDHA1 PE=2 SV=1
Length = 390
Score = 356 bits (911), Expect = 4e-097
Identities = 179/336 (53%), Positives = 236/336 (70%), Gaps = 4/336 (1%)
Frame = +3
Query: 177 PPSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAI 356
PP +V + ++ L ++R M +RRME+ AD LYK K+IRGFCHL DGQEA +G+EA I
Sbjct: 50 PPVTTV-LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGI 108
Query: 357 TKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGI 536
D +ITAYR H RG S+ E+ AEL GR+ GC++GKGGSMH Y K +FYGG+GI
Sbjct: 109 NPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGI 166
Query: 537 VGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNH 716
VGAQVPLG GIA A KY ++ V +YGDGAANQGQ+F A N++ALW LP I +CENN
Sbjct: 167 VGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFGAYNMAALWKLPCIFICENNR 226
Query: 717 YGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDT 893
YGMGT+ RAA S YYKRGD++PGL+VDGMD V++A +FA + GPI++E+ T
Sbjct: 227 YGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQT 286
Query: 894 YRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEV 1073
YRYHGHSMSDPG +YRTR+EI VR + DPI +K +++ +LA+ +ELK+++ E+RKE+
Sbjct: 287 YRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEI 346
Query: 1074 DDAIAKAKDCPMPEPSELFTNVYVKGFGTESFGADR 1181
+DA A P P EL ++Y E GA++
Sbjct: 347 EDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQ 382
>sp|P35487|ODPAT_MOUSE Pyruvate dehydrogenase E1 component subunit alpha,
testis-specific form, mitochondrial OS=Mus musculus GN=Pdha2 PE=2 SV=1
Length = 391
Score = 351 bits (900), Expect = 8e-096
Identities = 169/322 (52%), Positives = 229/322 (71%), Gaps = 3/322 (0%)
Frame = +3
Query: 180 PSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRGFCHLYDGQEAVAIGMEAAIT 359
P S + E L ++RTM ++RRME+ AD LYK K IRGFCHL DGQEA +G+EA I
Sbjct: 51 PPTSTVLTRAEALKYYRTMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGIN 110
Query: 360 KKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGKGGSMHFYKKDSSFYGGHGIV 539
D +IT+YR H RG S+ + AEL GR+ GC++GKGGSMH Y K +FYGG+GIV
Sbjct: 111 PTDHVITSYRAHGFCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYGK--NFYGGNGIV 168
Query: 540 GAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEALNISALWDLPSILVCENNHY 719
GAQVPLG G+AFA KY K V A+YGDGAANQGQ+FEA N+SALW LP + +CENN Y
Sbjct: 169 GAQVPLGAGVAFACKYLKNGQVCLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNLY 228
Query: 720 GMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACKFAKEHALK-NGPIILEMDTY 896
GMGT+ R+A S Y+K+G +PGL+V+GMD V++A KFA +H GPI++E+ TY
Sbjct: 229 GMGTSNERSAASTDYHKKGFIIPGLRVNGMDILCVREATKFAADHCRSGKGPIVMELQTY 288
Query: 897 RYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRKEVD 1076
RYHGHSMSDPG +YR+R+E+ VR + DPI +++ ++S++L+ +ELK+++ +++KEV+
Sbjct: 289 RYHGHSMSDPGISYRSREEVHNVRSKSDPIMLLRERIISNNLSNIEELKEIDADVKKEVE 348
Query: 1077 DAIAKAKDCPMPEPSELFTNVY 1142
DA A P P ++ +Y
Sbjct: 349 DAAQFATTDPEPAVEDIANYLY 370
>sp|P26267|ODPA_ASCSU Pyruvate dehydrogenase E1 component subunit alpha type I,
mitochondrial OS=Ascaris suum PE=1 SV=1
Length = 396
Score = 339 bits (868), Expect = 4e-092
Identities = 175/342 (51%), Positives = 231/342 (67%), Gaps = 5/342 (1%)
Frame = +3
Query: 123 TTPITIETSLPFTAHLCDP-PSRSVESSTQELLSFFRTMALMRRMEIAADSLYKAKLIRG 299
+T T +T PF H D P +V + ++ + ++ M +RRME AA +LYK K +RG
Sbjct: 27 STEATFQTK-PFKLHKLDSGPDINVHVTKEDAVHYYTQMLTIRRMESAAGNLYKEKKVRG 85
Query: 300 FCHLYDGQEAVAIGMEAAITKKDAIITAYRDHCIFLGRGGSLYEVFAELMGRRDGCSRGK 479
FCHLY GQEA A+G +AA+ DA +TAYR H G S+ +V EL GR G GK
Sbjct: 86 FCHLYSGQEACAVGTKAAMDAGDAAVTAYRCHGWTYLSGSSVAKVLCELTGRITGNVYGK 145
Query: 480 GGSMHFYKKDSSFYGGHGIVGAQVPLGCGIAFAQKYGKEEAVTFAMYGDGAANQGQLFEA 659
GGSMH Y +FYGG+GIVGAQ PLG GIAFA KY KE+ V M+GDGA NQGQLFE+
Sbjct: 146 GGSMHMY--GENFYGGNGIVGAQQPLGTGIAFAMKYRKEKNVCITMFGDGATNQGQLFES 203
Query: 660 LNISALWDLPSILVCENNHYGMGTAEWRAAKSPSYYKRGDYVPGLKVDGMDAFAVKQACK 839
+N++ LWDLP + VCENN YGMGTA R++ S YY RGDYVPG+ VDGMD AV+QA +
Sbjct: 204 MNMAKLWDLPVLYVCENNGYGMGTAAARSSASTDYYTRGDYVPGIWVDGMDVLAVRQAVR 263
Query: 840 FAKEHA-LKNGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSH 1016
+AKE GP+++EM TYRY GHSMSDPG++YRTR+E+ VR+ RDPI K +++
Sbjct: 264 WAKEWCNAGKGPLMIEMATYRYSGHSMSDPGTSYRTREEVQEVRKTRDPITGFKDKIVTA 323
Query: 1017 DLATEKELKDMEKEIRKEVDDAIAKAKDCPMPEPSELFTNVY 1142
L TE E+K+++K++RKE+D A+ +A + T++Y
Sbjct: 324 GLVTEDEIKEIDKQVRKEIDAAVKQAHTDKESPVELMLTDIY 365
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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