BLASTX 7.6.2
Query= UN20064 /QuerySize=943
(942 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VDL1|U483_DROME UPF0483 protein CG5412 OS=Drosophila melano... 91 1e-017
sp|Q29BR3|U483_DROPS UPF0483 protein GA18864 OS=Drosophila pseud... 84 1e-015
sp|P36591|DYR_SCHPO Dihydrofolate reductase OS=Schizosaccharomyc... 75 6e-013
sp|A4II73|OVCA2_XENTR Ovarian cancer-associated gene 2 protein h... 74 2e-012
sp|Q3SZ07|OVCA2_BOVIN Ovarian cancer-associated gene 2 protein h... 67 2e-010
sp|Q9D7E3|OVCA2_MOUSE Ovarian cancer-associated gene 2 protein h... 65 5e-010
sp|Q61YZ4|U483_CAEBR UPF0483 protein CBG03338 OS=Caenorhabditis ... 65 8e-010
sp|Q7QBJ0|U483_ANOGA UPF0483 protein AGAP003155 OS=Anopheles gam... 64 2e-009
sp|Q99369|FSH3_YEAST Family of serine hydrolases 3 OS=Saccharomy... 63 2e-009
sp|Q8WZ82|OVCA2_HUMAN Ovarian cancer-associated gene 2 protein O... 63 2e-009
sp|Q18169|U483_CAEEL UPF0483 protein C25G4.2 OS=Caenorhabditis e... 60 2e-008
sp|O13897|YF36_SCHPO Uncharacterized hydrolase C22A12.06c OS=Sch... 60 2e-008
sp|Q503Y4|OVCA2_DANRE Ovarian cancer-associated gene 2 protein h... 59 3e-008
sp|Q05015|FSH2_YEAST Family of serine hydrolases 2 OS=Saccharomy... 59 4e-008
>sp|Q9VDL1|U483_DROME UPF0483 protein CG5412 OS=Drosophila melanogaster
GN=CG5412 PE=2 SV=1
Length = 279
Score = 91 bits (223), Expect = 1e-017
Identities = 74/231 (32%), Positives = 110/231 (47%), Gaps = 24/231 (10%)
Frame = -1
Query: 828 IVRKPRFLCLHGFRTSGEIMKIQLHKWPKSVIDRLDLVFLDAPFPCQG-KSDVEGIFDPP 652
I K R LCLHG+R +GE K +L + K + VF+ AP + +S E + P
Sbjct: 27 ITEKVRVLCLHGYRQNGEAFKNKLGSFRKFANKYAEFVFITAPHVAKALESAAEPV--PE 84
Query: 651 YYEWFQFNKEFNEY--TN-------FEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLP 499
W+ NK+ + TN F++ L +E++ GPF GL+GFSQGA G +
Sbjct: 85 QRSWWA-NKDDGSFKGTNKGGPAFGFQESLRCVEEAWRTQGPFQGLLGFSQGACFVGLIC 143
Query: 498 GLQARGIALQKVPKIK--FIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDFL--KP 331
GL A +K+ I+ F ++ G + V AY + P+LH G+TD + K
Sbjct: 144 GL-----AKKKLTSIRPEFAVLASG-FLSGSLVHMSAYEEAISIPTLHIYGQTDEIIPKE 197
Query: 330 YGTELIDSFKNPVVVNHPKGHTVPRLDEKSLEKVTAFIDTI-EHLLMEELK 181
L FKN V+ H GH P ++ + F D + E+L EEL+
Sbjct: 198 MSESLAARFKNAEVLEHSGGHYFPATAQQKQTFINFFQDRLQEYLEHEELQ 248
>sp|Q29BR3|U483_DROPS UPF0483 protein GA18864 OS=Drosophila pseudoobscura
pseudoobscura GN=GA18864 PE=3 SV=1
Length = 289
Score = 84 bits (206), Expect = 1e-015
Identities = 67/237 (28%), Positives = 107/237 (45%), Gaps = 22/237 (9%)
Frame = -1
Query: 828 IVRKPRFLCLHGFRTSGEIMKIQLHKWPKSVIDRLDLVFLDAPFPCQGKSDVEGIFDP-P 652
I K R LCLHG+R G+ K +L + K + VF+ AP + +E +P P
Sbjct: 27 ITEKVRVLCLHGYRQDGDAFKNKLGSFRKFTSKYAEFVFISAPHIA---APLESAAEPVP 83
Query: 651 YYEWFQFNKEFNEY--TN-------FEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLP 499
+ NK+ + TN F+ L +E++ GPF GL+GFSQGA G +
Sbjct: 84 EQRSWWANKDDGTFKGTNKGGPAFGFQDSLRLVEEAWKTQGPFQGLLGFSQGACFVGLIC 143
Query: 498 GLQARGIALQKVPKIK-FIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDFL--KPY 328
GL A +K+ I+ ++ + V AY + P+LH G +D + K
Sbjct: 144 GL-----AKKKLTSIRPEFAVLSSGFVSGSLVHMSAYEEPVSIPTLHIYGSSDEIIPKDM 198
Query: 327 GTELIDSFKNPVVVNHPKGHTVPRLDEKSLEKVTAFIDTIEHLLMEELKIDEEATTN 157
L FKN V+ H GH P ++ + F D ++ L E L++ + ++ +
Sbjct: 199 SALLASHFKNVEVLEHGGGHYFPATAQQKQTYINFFQDRLQEYL-EHLELQQSSSVS 254
>sp|P36591|DYR_SCHPO Dihydrofolate reductase OS=Schizosaccharomyces pombe
GN=dfr1 PE=2 SV=2
Length = 461
Score = 75 bits (183), Expect = 6e-013
Identities = 48/137 (35%), Positives = 73/137 (53%), Gaps = 8/137 (5%)
Frame = -1
Query: 648 YEWFQFNKEFNEYTNFEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQARG---I 478
+ WF+ N Y ++++ LE I + + GPFDGLIGFSQGA + L + G
Sbjct: 73 FGWFEVEDFKNTYGSWDESLECINQYMQEKGPFDGLIGFSQGAGIGAMLAQMLQPGQPPN 132
Query: 477 ALQKVPKIKFIIIIGGAMFKSTKVAKD-AYSSTMDTPSLHFLGETDFLKPY--GTELIDS 307
+ P KF++ +GG F++ K D Y+ + TPSLH G +D L P +L++
Sbjct: 133 PYVQHPPFKFVVFVGG--FRAEKPEFDHFYNPKLTTPSLHIAGTSDTLVPLARSKQLVER 190
Query: 306 FKNPVVVNHPKGHTVPR 256
+N V+ HP H VP+
Sbjct: 191 CENAHVLLHPGQHIVPQ 207
>sp|A4II73|OVCA2_XENTR Ovarian cancer-associated gene 2 protein homolog
OS=Xenopus tropicalis GN=ovca2 PE=2 SV=2
Length = 230
Score = 74 bits (179), Expect = 2e-012
Identities = 48/137 (35%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Frame = -1
Query: 663 FDPPYYEWFQFNKEFNEYTNFEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQAR 484
F P F +E + E L+ + + +LGPFDG++GFSQGA L + L+ +
Sbjct: 80 FSNPEQNSFDAMEESKTCSGLEAPLDTVAKAFSELGPFDGILGFSQGAALVAIICALKQQ 139
Query: 483 GIALQKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETD--FLKPYGTELID 310
G F I++ G ST AK Y + PSLH +GETD EL+
Sbjct: 140 G---DPRFHFDFAILVAGFKSLSTDHAKH-YQQPITVPSLHVIGETDRVISAAMSQELVS 195
Query: 309 SFKNPVVVNHPKGHTVP 259
F+NPV++ H GH VP
Sbjct: 196 HFENPVILMHSGGHYVP 212
>sp|Q3SZ07|OVCA2_BOVIN Ovarian cancer-associated gene 2 protein homolog OS=Bos
taurus GN=OVCA2 PE=2 SV=1
Length = 227
Score = 67 bits (162), Expect = 2e-010
Identities = 44/149 (29%), Positives = 70/149 (46%), Gaps = 5/149 (3%)
Frame = -1
Query: 696 PCQGKSDVEG-IFDPPYYEWFQFNKEFNEYTNFEKCLEYIEDSVIKLGPFDGLIGFSQGA 520
PC + +G F + F +E E+ LE + ++ KLGPFDG++GFSQGA
Sbjct: 63 PCPPEEQPQGWWFSEQEADVFLALEEPTACRGLEEALETVAQALNKLGPFDGILGFSQGA 122
Query: 519 ILSGGLPGLQARGIALQKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDF 340
L+ + L G + P +F+I++ G + + + + PSLH G+TD
Sbjct: 123 ALAALVCALGQGGD--PRFPLPRFVILVSGFCPRGLGLMEPIMQGPLSLPSLHVFGDTDG 180
Query: 339 LKP--YGTELIDSFKNPVVVNHPKGHTVP 259
+ P +L F V + H GH +P
Sbjct: 181 VIPSQESMQLCSRFDGAVTLTHSGGHFIP 209
>sp|Q9D7E3|OVCA2_MOUSE Ovarian cancer-associated gene 2 protein homolog OS=Mus
musculus GN=Ovca2 PE=2 SV=1
Length = 225
Score = 65 bits (158), Expect = 5e-010
Identities = 47/149 (31%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Frame = -1
Query: 696 PCQGKSDVEG-IFDPPYYEWFQFNKEFNEYTNFEKCLEYIEDSVIKLGPFDGLIGFSQGA 520
PC + G F + F +E ++ LE + ++ LGPFDGL+GFSQGA
Sbjct: 63 PCSPEEQPRGWWFSEEEADVFSALEESTVCRGLQEALETVARALDTLGPFDGLLGFSQGA 122
Query: 519 ILSGGLPGLQARGIALQKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDF 340
L+ + L G + P +FII++ G F + + S M PSLH G+TD
Sbjct: 123 ALAAYVCALGQAGD--PRFPLPRFIILVSG--FCPRGLKEPILQSPMSLPSLHVFGDTDR 178
Query: 339 LKP--YGTELIDSFKNPVVVNHPKGHTVP 259
+ P +L F V + H GH +P
Sbjct: 179 VIPSQESMQLASRFLGAVTLTHSGGHFIP 207
>sp|Q61YZ4|U483_CAEBR UPF0483 protein CBG03338 OS=Caenorhabditis briggsae
GN=CBG03338 PE=3 SV=1
Length = 220
Score = 65 bits (156), Expect = 8e-010
Identities = 47/138 (34%), Positives = 72/138 (52%), Gaps = 12/138 (8%)
Frame = -1
Query: 621 FNEYTNFEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQARGIALQKVPKIKFII 442
F+E N +++IED+ GPFDGL+GFSQGA + L + + K+P I+F I
Sbjct: 82 FDESVN--AVVKFIEDN----GPFDGLLGFSQGASMVHLL--IAKAQLGEIKLPGIRFAI 133
Query: 441 IIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDFL--KPYGTELIDSF-KNPVVVNHPKG 271
G + S+K D PS+H G++D + +P +L D F P+ + H G
Sbjct: 134 FFSGFLSLSSKHDTLTSLRIKDFPSMHVFGDSDEIVARPKSEKLADQFDMEPIRIAHEGG 193
Query: 270 HTVPRLDEKSLEKVTAFI 217
H VP + K E++T F+
Sbjct: 194 HLVPSM-SKHKERITQFL 210
>sp|Q7QBJ0|U483_ANOGA UPF0483 protein AGAP003155 OS=Anopheles gambiae
GN=AGAP003155 PE=3 SV=3
Length = 266
Score = 64 bits (153), Expect = 2e-009
Identities = 47/126 (37%), Positives = 64/126 (50%), Gaps = 9/126 (7%)
Frame = -1
Query: 546 GLIGFSQGAILSGGLPGLQARGIALQKVPKIKFIIIIGGAMFKS-TKVAKDAYSSTMDTP 370
GL+GFSQGA G L L ARG+ K +F ++ G F+S + V + Y + + P
Sbjct: 109 GLLGFSQGACFVGLLCDLSARGMTTMKP---QFAVVASG--FRSGSLVHLNYYENKVQIP 163
Query: 369 SLHFLGETD--FLKPYGTELIDSFKNPVVVNHPKGHTVPRLDEKSLEKVTAFIDTI-EHL 199
SLH GETD K L ++F +P VV HP GH P V F D + +HL
Sbjct: 164 SLHIFGETDEIITKDMSEALAETFLDPEVVTHPGGHYFPAQASLKETYVDFFRDQLQQHL 223
Query: 198 LMEELK 181
+EL+
Sbjct: 224 EAKELQ 229
>sp|Q99369|FSH3_YEAST Family of serine hydrolases 3 OS=Saccharomyces cerevisiae
GN=FSH3 PE=1 SV=1
Length = 266
Score = 63 bits (152), Expect = 2e-009
Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
Frame = -1
Query: 648 YEWFQFNKE-FNEYTNFEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQARGIAL 472
Y WF N E FN + +K Y+ + V++ GPFDG+IGFSQGA L G L R + L
Sbjct: 77 YGWFFRNPESFNSFQIDQKVFNYLRNYVLENGPFDGVIGFSQGAGLGGYLVTDFNRILNL 136
Query: 471 --QKVPKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETD 343
++ P +KF I G + K+ Y + PSLH GE D
Sbjct: 137 TDEQQPALKFFISFSGFKLEDQSYQKE-YHRIIQVPSLHVRGELD 180
>sp|Q8WZ82|OVCA2_HUMAN Ovarian cancer-associated gene 2 protein OS=Homo sapiens
GN=OVCA2 PE=1 SV=1
Length = 227
Score = 63 bits (152), Expect = 2e-009
Identities = 36/116 (31%), Positives = 58/116 (50%), Gaps = 4/116 (3%)
Frame = -1
Query: 600 EKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQARGIALQKVPKIKFIIIIGGAMF 421
E+ L + ++ +LGPFDGL+GFSQGA L+ + L G + P +FI+++ G
Sbjct: 96 EESLGMVAQALNRLGPFDGLLGFSQGAALAALVCALGQAGD--PRFPLPRFILLVSGFCP 153
Query: 420 KSTKVAKDAYSSTMDTPSLHFLGETDFLKP--YGTELIDSFKNPVVVNHPKGHTVP 259
+ + + PSLH G+TD + P +L F + + H GH +P
Sbjct: 154 RGIGFKESILQRPLSLPSLHVFGDTDKVIPSQESVQLASQFPGAITLTHSGGHFIP 209
>sp|Q18169|U483_CAEEL UPF0483 protein C25G4.2 OS=Caenorhabditis elegans
GN=C25G4.2 PE=2 SV=1
Length = 221
Score = 60 bits (145), Expect = 2e-008
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 6/132 (4%)
Frame = -1
Query: 603 FEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQARGIALQKVPKIKFIIIIGGAM 424
FE+ + + + + GPFDGL+GFSQGA + L + + K+P I+F I G +
Sbjct: 82 FEESVAAVVKFIEENGPFDGLLGFSQGASMVHLL--IAKAQLGEIKLPGIRFAIFFSGFL 139
Query: 423 FKSTKVAKDAYSSTMDTPSLHFLGETDFL--KPYGTELIDSFK-NPVVVNHPKGHTVPRL 253
S+K + PS+H G+ D + +P ++ D F P+ + H GH VP +
Sbjct: 140 SLSSKHDSLTLLRIKEFPSMHVFGDADEIVARPKSEKMADMFDVEPLRIAHDGGHVVPSM 199
Query: 252 DEKSLEKVTAFI 217
K EK+ F+
Sbjct: 200 -SKHKEKIAGFM 210
>sp|O13897|YF36_SCHPO Uncharacterized hydrolase C22A12.06c
OS=Schizosaccharomyces pombe GN=SPAC22A12.06c PE=2 SV=1
Length = 429
Score = 60 bits (145), Expect = 2e-008
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 17/153 (11%)
Frame = -1
Query: 642 WFQFNKEFNEYTNFE--KCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQARGIALQ 469
W++ N E+ + E K EY+ + + GPFDG++GFSQG L+ L L + +
Sbjct: 78 WWRIN-EYADTKQLEPTKAFEYLASYIKEHGPFDGILGFSQGTNLAANLAAL----VTIP 132
Query: 468 KV------PKIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDFL--KPYGTELI 313
K P +F + G F+ + +++ +D P+LH LG+ D + T L+
Sbjct: 133 KYQEYFSQPPFRFALFFSG-YFRPLLMDGAVHATKLDLPTLHLLGKYDTVLSTETSTTLV 191
Query: 312 DSFKNPVVVNHPKGHTVPRLDEKSLEKVTAFID 214
+ K+ V+ HP H +P +E FID
Sbjct: 192 RACKDAQVLFHPAAHQIP-APHAYVEPAADFID 223
>sp|Q503Y4|OVCA2_DANRE Ovarian cancer-associated gene 2 protein homolog OS=Danio
rerio GN=ovca2 PE=2 SV=1
Length = 227
Score = 59 bits (142), Expect = 3e-008
Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 4/129 (3%)
Frame = -1
Query: 639 FQFNKEFNEYTNFEKCLEYIEDSVIKLGPFDGLIGFSQGAILSGGLPGLQARGIALQKVP 460
F ++ E+ +E ++ ++ LGPF G++GFSQGA L L LQ + L+
Sbjct: 84 FNAKQDCESSLGLEESIEAVKAALKDLGPFSGILGFSQGAALVAMLCALQEQ--KLEPDF 141
Query: 459 KIKFIIIIGGAMFKSTKVAKDAYSSTMDTPSLHFLGETDFLKP--YGTELIDSFKNPVVV 286
+F I++ G + + + PSLH G+ D + P +L+ +F V+
Sbjct: 142 NFRFAILVAGFRSACLEHQRFYEGPVITIPSLHVFGQDDRVIPEEMSRDLLPAFDGAQVL 201
Query: 285 NHPKGHTVP 259
HP GH VP
Sbjct: 202 LHPGGHFVP 210
>sp|Q05015|FSH2_YEAST Family of serine hydrolases 2 OS=Saccharomyces cerevisiae
GN=FSH2 PE=1 SV=1
Length = 223
Score = 59 bits (141), Expect = 4e-008
Identities = 47/171 (27%), Positives = 78/171 (45%), Gaps = 19/171 (11%)
Frame = -1
Query: 747 PKSVIDRLDLVFLDAPFPCQGKSDVEGIFDPPYYEWFQFNKEFNEYTNFEKCLEYIEDSV 568
P V D L V DAP G + G+ W + + Y + ++Y+ + V
Sbjct: 47 PADVPDFLGEVIADAP----GDGENTGVL-----AWLENDPSTGGYFIPQTTIDYLHNYV 97
Query: 567 IKLGPFDGLIGFSQGAILSGGLP----GLQARGIALQKVPKIKFIIIIGGAMFKSTKVAK 400
++ GPF G++GFSQGA ++G L GL G+ ++ P ++F + + G F+ + +
Sbjct: 98 LENGPFAGIVGFSQGAGVAGYLATDFNGL--LGLTTEEQPPLEFFMAVSGFRFQPQQYQE 155
Query: 399 DAYSSTMDTPSLHFLGETDFL----KPYGTELIDSFKNPVVVNHPKGHTVP 259
+ PSLH GE D + K G + + ++ H GH VP
Sbjct: 156 QYDLHPISVPSLHVQGELDTITEPAKVQGLYNSCTEDSRTLLMHSGGHFVP 206
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,872,592,117
Number of Sequences: 518415
Number of Extensions: 81872592117
Number of Successful Extensions: 541474699
Number of sequences better than 0.0: 0
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