BLASTX 7.6.2
Query= UN20084 /QuerySize=1300
(1299 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Ratt... 106 4e-022
sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Ga... 105 8e-022
sp|O15460|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 OS=Ho... 104 2e-021
sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mu... 103 4e-021
sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mu... 102 5e-021
sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Ga... 102 9e-021
sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Ho... 100 4e-020
sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Po... 100 4e-020
sp|Q10576|P4HA1_CAEEL Prolyl 4-hydroxylase subunit alpha-1 OS=Ca... 99 6e-020
sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bo... 98 1e-019
>sp|P54001|P4HA1_RAT Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 106 bits (264), Expect = 4e-022
Identities = 62/151 (41%), Positives = 84/151 (55%), Gaps = 5/151 (3%)
Frame = +1
Query: 436 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 615
+PR + +H+ +++ E E + LAKP + ++TV D +TG ++ R S +L D V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPV 393
Query: 616 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 783
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATW 453
Query: 784 LMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
L Y+SDV GG TVFP G V GTA+
Sbjct: 454 LFYMSDVSAGGATVFPEV-GASVWPKKGTAV 483
>sp|Q5ZLK5|P4HA2_CHICK Prolyl 4-hydroxylase subunit alpha-2 OS=Gallus gallus
GN=P4HA2 PE=2 SV=1
Length = 534
Score = 105 bits (261), Expect = 8e-022
Identities = 59/151 (39%), Positives = 91/151 (60%), Gaps = 4/151 (2%)
Frame = +1
Query: 433 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 609
W+ P V Y++ +++EE E + LAKP + ++TV D KTG + R S ++L+ D
Sbjct: 334 WDSPHIVRYYDVMSDEEIEKIKQLAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 393
Query: 610 HVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLDEFNT--KNGGQRIATV 783
VV ++ QR+ T + V+ E LQV +Y +G +YEPH+D+ F++ K+ G R+AT
Sbjct: 394 PVVAKVNQRMQQITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSTLKSEGNRLATF 453
Query: 784 LMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
L Y+SDV+ GG TVFP G + GTA+
Sbjct: 454 LNYMSDVEAGGATVFPDF-GAAIWPKKGTAV 483
>sp|O15460|P4HA2_HUMAN Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens
GN=P4HA2 PE=1 SV=1
Length = 535
Score = 104 bits (257), Expect = 2e-021
Identities = 59/153 (38%), Positives = 88/153 (57%), Gaps = 6/153 (3%)
Frame = +1
Query: 433 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 609
W+ P V Y++ +++EE E + +AKP + ++TV D KTG + R S ++L+ D
Sbjct: 333 WDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392
Query: 610 HVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYF----LDEFNTKNGGQRIA 777
VV R+ +R+ T + V+ E LQV +Y VG +YEPH+D+ D F G R+A
Sbjct: 393 PVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVA 452
Query: 778 TVLMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
T L Y+SDV+ GG TVFP G + GTA+
Sbjct: 453 TFLNYMSDVEAGGATVFPDL-GAAIWPKKGTAV 484
>sp|Q60716|P4HA2_MOUSE Prolyl 4-hydroxylase subunit alpha-2 OS=Mus musculus
GN=P4ha2 PE=2 SV=1
Length = 537
Score = 103 bits (255), Expect = 4e-021
Identities = 58/153 (37%), Positives = 88/153 (57%), Gaps = 6/153 (3%)
Frame = +1
Query: 433 WE-PRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHD 609
W+ P V Y++ +++EE E + +AKP + ++TV D KTG + R S ++L+ D
Sbjct: 335 WDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 394
Query: 610 HVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIA 777
VV R+ +R+ T + V+ E LQV +Y +G +YEPH+D+ D F G R+A
Sbjct: 395 PVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVA 454
Query: 778 TVLMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
T L Y+SDV+ GG TVFP G + GTA+
Sbjct: 455 TFLNYMSDVEAGGATVFPDL-GAAIWPKKGTAV 486
>sp|Q60715|P4HA1_MOUSE Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus
GN=P4ha1 PE=2 SV=2
Length = 534
Score = 102 bits (254), Expect = 5e-021
Identities = 60/151 (39%), Positives = 82/151 (54%), Gaps = 5/151 (3%)
Frame = +1
Query: 436 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 615
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L D V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPV 393
Query: 616 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 783
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATW 453
Query: 784 LMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
L Y+SDV GG TVFP G V GTA+
Sbjct: 454 LFYMSDVSAGGATVFPEV-GASVWPKKGTAV 483
>sp|P16924|P4HA1_CHICK Prolyl 4-hydroxylase subunit alpha-1 OS=Gallus gallus
GN=P4HA1 PE=1 SV=1
Length = 516
Score = 102 bits (252), Expect = 9e-021
Identities = 62/151 (41%), Positives = 82/151 (54%), Gaps = 5/151 (3%)
Frame = +1
Query: 436 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 615
+PR V + + +++EE E + LAKP + ++TV D +TG + R S +L V
Sbjct: 316 KPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPV 375
Query: 616 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 783
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 376 VSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATW 435
Query: 784 LMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
L Y+SDV GG TVFP G V GTA+
Sbjct: 436 LFYMSDVSAGGATVFPEV-GASVWPKKGTAV 465
Score = 54 bits (128), Expect = 2e-006
Identities = 23/47 (48%), Positives = 29/47 (61%)
Frame = +2
Query: 893 GLSVLPKKRDALLFWNMRPDASLDPSSLHGGCPVVKGNKWSSTKWFH 1033
G SV PKK A+ ++N+ P D S+ H CPV+ GNKW S KW H
Sbjct: 454 GASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLH 500
>sp|P13674|P4HA1_HUMAN Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens
GN=P4HA1 PE=1 SV=2
Length = 534
Score = 100 bits (247), Expect = 4e-020
Identities = 59/151 (39%), Positives = 82/151 (54%), Gaps = 5/151 (3%)
Frame = +1
Query: 436 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 615
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 616 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 783
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 784 LMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
L Y+SDV GG TVFP G V GTA+
Sbjct: 454 LFYMSDVSAGGATVFPEV-GASVWPKKGTAV 483
>sp|Q5RAG8|P4HA1_PONAB Prolyl 4-hydroxylase subunit alpha-1 OS=Pongo abelii
GN=P4HA1 PE=2 SV=1
Length = 534
Score = 100 bits (247), Expect = 4e-020
Identities = 59/151 (39%), Positives = 82/151 (54%), Gaps = 5/151 (3%)
Frame = +1
Query: 436 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 615
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 616 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 783
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 784 LMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
L Y+SDV GG TVFP G V GTA+
Sbjct: 454 LFYMSDVSAGGATVFPEV-GASVWPKKGTAV 483
>sp|Q10576|P4HA1_CAEEL Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabditis
elegans GN=dpy-18 PE=1 SV=2
Length = 559
Score = 99 bits (245), Expect = 6e-020
Identities = 54/149 (36%), Positives = 83/149 (55%), Gaps = 4/149 (2%)
Frame = +1
Query: 418 VEVISWEPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLK 597
VE+ + P AV++ + ++++E + LAKP + ++TV D TG + R S +LK
Sbjct: 321 VEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLK 380
Query: 598 RGHDHVVERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLDE----FNTKNGG 765
VVE + +RI T + +E E LQ+ +Y +G Y+PH+D+ E F + G
Sbjct: 381 EWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTG 440
Query: 766 QRIATVLMYLSDVDDGGETVFPAAKGTLV 852
RIATVL Y+S GG TVF AK T++
Sbjct: 441 NRIATVLFYMSQPSHGGGTVFTEAKSTIL 469
>sp|Q1RMU3|P4HA1_BOVIN Prolyl 4-hydroxylase subunit alpha-1 OS=Bos taurus
GN=P4HA1 PE=1 SV=1
Length = 534
Score = 98 bits (243), Expect = 1e-019
Identities = 59/151 (39%), Positives = 82/151 (54%), Gaps = 5/151 (3%)
Frame = +1
Query: 436 EPRAVVYHNFLTNEECEHLISLAKPNMVKSTVVDEKTGGSKDSRVRTSSGTFLKRGHDHV 615
+PR + +H+ +++ E E + LAKP + ++T+ + TG + R S +L + V
Sbjct: 334 KPRIIRFHDIISDAEIEVVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPV 393
Query: 616 VERIEQRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFL----DEFNTKNGGQRIATV 783
V RI RI D T + V E LQV +Y VG +YEPH+D+ D F G RIAT
Sbjct: 394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATW 453
Query: 784 LMYLSDVDDGGETVFPAAKGTLVQSHGGTAL 876
L Y+SDV GG TVFP G V GTA+
Sbjct: 454 LFYMSDVLAGGATVFPEV-GASVWPKKGTAV 483
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,405,176,235
Number of Sequences: 518415
Number of Extensions: 82405176235
Number of Successful Extensions: 554174885
Number of sequences better than 0.0: 0
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