BLASTX 7.6.2
Query= UN20145 /QuerySize=876
(875 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabi... 215 4e-055
sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase D... 162 3e-039
sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase D... 154 7e-037
sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kin... 154 1e-036
sp|Q9ESL4|MLTK_MOUSE Mitogen-activated protein kinase kinase kin... 154 1e-036
sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase ki... 140 1e-032
sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dic... 137 1e-031
sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Ara... 135 6e-031
sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase dr... 130 2e-029
sp|P18161|PYK2_DICDI Dual specificity protein kinase pyk2 OS=Dic... 129 3e-029
sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/thre... 123 2e-027
sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/thre... 122 4e-027
sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase D... 116 2e-025
sp|Q6XHA7|ROCO9_DICDI Probable serine/threonine-protein kinase r... 109 3e-023
sp|Q8VDG6|M3KL4_MOUSE Mitogen-activated protein kinase kinase ki... 102 3e-021
sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase ki... 102 4e-021
sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase ki... 102 5e-021
sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase ki... 102 5e-021
sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kina... 102 5e-021
sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase ki... 100 2e-020
>sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabidopsis thaliana
GN=HT1 PE=1 SV=1
Length = 390
Score = 215 bits (546), Expect = 4e-055
Identities = 98/188 (52%), Positives = 132/188 (70%)
Frame = -2
Query: 871 CIKPMVLCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHERNFIHRDL 692
C KP V CI+TEY G++R +L K++ ++ ++ ++ ALD++RGM Y+H + IHRDL
Sbjct: 154 CKKPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDL 213
Query: 691 KSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFG 512
KS+NLL++ + +K+ADFG + +E Q GTYRWMAPEMI+ +PYT+KVDVYSFG
Sbjct: 214 KSNNLLLNDEMRVKVADFGTSCLETQCREAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFG 273
Query: 511 IVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCF 332
IVLWEL T LLPFQ MT VQAAFAV + RP +P C P L ++ RCW +P RP F
Sbjct: 274 IVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDF 333
Query: 331 AEIVNLLE 308
+ IV +LE
Sbjct: 334 SNIVAVLE 341
>sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DDB_G0267514
OS=Dictyostelium discoideum GN=DDB_G0267514 PE=3 SV=1
Length = 916
Score = 162 bits (409), Expect = 3e-039
Identities = 79/187 (42%), Positives = 118/187 (63%), Gaps = 1/187 (0%)
Frame = -2
Query: 871 CIKPMVLCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHERNFIHRDL 692
C P LC +TEY GGS+ L ++ + + ++L K A+ +A+GM Y+H IHRD+
Sbjct: 727 CTAPPNLCFITEYLPGGSLYDALHSKKIK-MNMQLYKKLAIQIAQGMNYLHLSGVIHRDI 785
Query: 691 KSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFG 512
KS NLL+ ++KI DFG+++++ ++ MT G+ WM+PE++ YT+KVDVY+FG
Sbjct: 786 KSLNLLLDEHMNVKICDFGLSKLKSKSTEMTKSIGSPIWMSPELLMGEDYTEKVDVYAFG 845
Query: 511 IVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCF 332
I+LWEL TG LP+ + +VQ A AV + +RP +P L ++ CW DP RP F
Sbjct: 846 IILWELGTGELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSF 905
Query: 331 AEIVNLL 311
EI+NLL
Sbjct: 906 TEILNLL 912
>sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DDB_G0272254
OS=Dictyostelium discoideum GN=DDB_G0272254 PE=3 SV=1
Length = 1331
Score = 154 bits (389), Expect = 7e-037
Identities = 80/186 (43%), Positives = 115/186 (61%), Gaps = 6/186 (3%)
Frame = -2
Query: 853 LCIVTEYAKGGSVRQFLTKR---QNRAVPL--KLAVKQALDVARGMAYVHERNFIHRDLK 689
+CIV E+ G++ + + + Q +++ L L + A D+ARGM ++H RN IHRDLK
Sbjct: 1143 MCIVMEFLPSGNLFELIHSKPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLK 1202
Query: 688 SDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGI 509
S NLL+ +IKIAD G+AR T+ MT GT W APE+++H Y QK DVYS+ I
Sbjct: 1203 SSNLLMDKHFNIKIADLGIARETSFTQTMT-TIGTVAWTAPEILRHESYNQKADVYSYAI 1261
Query: 508 VLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFA 329
VL+EL+TG P+Q + + A V ++G+RP +P +C P +++ CW DP RP F
Sbjct: 1262 VLYELLTGEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFE 1321
Query: 328 EIVNLL 311
EI N L
Sbjct: 1322 EITNYL 1327
>sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo
sapiens GN=MLTK PE=1 SV=2
Length = 800
Score = 154 bits (387), Expect = 1e-036
Identities = 80/214 (37%), Positives = 125/214 (58%), Gaps = 11/214 (5%)
Frame = -2
Query: 868 IKPMVLCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHER---NFIHR 698
++P IVTEYA GS+ ++ ++ + + + A DVA+GM Y+H IHR
Sbjct: 73 LEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHR 132
Query: 697 DLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYS 518
DLKS N++I+AD +KI DFG +R T M+ GT+ WMAPE+IQ P ++ D YS
Sbjct: 133 DLKSRNVVIAADGVLKICDFGASRFHNHTTHMS-LVGTFPWMAPEVIQSLPVSETCDTYS 191
Query: 517 FGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRP 338
+G+VLWE++T +PF+ + +Q A+ VV + R T+P C E++ +CW+AD + RP
Sbjct: 192 YGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRP 251
Query: 337 CFAEIVNLLEGAETEVMTTVR-------KARFRC 257
F +I+++LE + + KA +RC
Sbjct: 252 SFKQIISILESMSNDTSLPDKCNSFLHNKAEWRC 285
>sp|Q9ESL4|MLTK_MOUSE Mitogen-activated protein kinase kinase kinase MLT OS=Mus
musculus GN=Mltk PE=1 SV=1
Length = 802
Score = 154 bits (387), Expect = 1e-036
Identities = 76/195 (38%), Positives = 120/195 (61%), Gaps = 4/195 (2%)
Frame = -2
Query: 868 IKPMVLCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHER---NFIHR 698
++P IVTEYA GS+ ++ ++ + ++ + A DVA+GM Y+H IHR
Sbjct: 73 LEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHR 132
Query: 697 DLKSDNLLISADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYS 518
DLKS N++I+AD +KI DFG +R T M+ GT+ WMAPE+IQ P ++ D YS
Sbjct: 133 DLKSRNVVIAADGVLKICDFGASRFHNHTTHMS-LVGTFPWMAPEVIQSLPVSETCDTYS 191
Query: 517 FGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRP 338
+G+VLWE++T +PF+ + +Q A+ VV + R T+P C E++ +CW+AD + RP
Sbjct: 192 YGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRP 251
Query: 337 CFAEIVNLLEGAETE 293
F +I+++LE +
Sbjct: 252 SFKQIISILESMSND 266
>sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kinase
OS=Drosophila melanogaster GN=slpr PE=1 SV=1
Length = 1161
Score = 140 bits (352), Expect = 1e-032
Identities = 78/208 (37%), Positives = 112/208 (53%), Gaps = 16/208 (7%)
Frame = -2
Query: 853 LCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHER---NFIHRDLKSD 683
LC+V EYA+GGS+ + L + +P + V A+ +ARGM Y+H + IHRDLKS
Sbjct: 213 LCLVMEYARGGSLNRILAGK----IPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSS 268
Query: 682 NLLI--------SADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVD 527
N+LI +++KI DFG+AR T+ M+ GTY WM PE+I Y++ D
Sbjct: 269 NVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMS-AAGTYAWMPPEVISVSTYSKFSD 327
Query: 526 VYSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPE 347
V+S+G++LWELITG P++ + A+ V + +P C G +M CW DP
Sbjct: 328 VWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPH 387
Query: 346 VRPCFAEIVNLLEGAETEVMTTVRKARF 263
RP F EI+ LE T + F
Sbjct: 388 KRPGFKEILKQLESIACSKFTLTPQESF 415
>sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dictyostelium
discoideum GN=pyk3 PE=1 SV=1
Length = 1338
Score = 137 bits (344), Expect = 1e-031
Identities = 74/191 (38%), Positives = 112/191 (58%), Gaps = 10/191 (5%)
Frame = -2
Query: 871 CIKPMVLCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHERNFIHRDL 692
CI P CI TEY +GGS+ L ++ + PL + K D++ GM ++H +HRDL
Sbjct: 1119 CIDPP--CIFTEYLQGGSLYDVLHIQKIKLNPL-MMYKMIHDLSLGMEHLHSIQMLHRDL 1175
Query: 691 KSDNLLISADRSIKIADFGVARI---EVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVY 521
S N+L+ ++IKIADFG+A ++ G+T RW +PE+ + Y +KVDVY
Sbjct: 1176 TSKNILLDEFKNIKIADFGLATTLSDDMTLSGIT----NPRWRSPELTKGLVYNEKVDVY 1231
Query: 520 SFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVR 341
SFG+V++E+ TG +PF+ + +A RP +P DC L +++T+CW +DP R
Sbjct: 1232 SFGLVVYEIYTGKIPFEGLDGTASAAKAAFENYRPAIPPDCPVSLRKLITKCWASDPSQR 1291
Query: 340 PCFAEIVNLLE 308
P F EI+ LE
Sbjct: 1292 PSFTEILTELE 1302
>sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arabidopsis
thaliana GN=CTR1 PE=1 SV=1
Length = 821
Score = 135 bits (338), Expect = 6e-031
Identities = 76/188 (40%), Positives = 108/188 (57%), Gaps = 4/188 (2%)
Frame = -2
Query: 862 PMVLCIVTEYAKGGSVRQFLTKRQNR-AVPLKLAVKQALDVARGMAYVHERN--FIHRDL 692
P L IVTEY GS+ + L K R + + + A DVA+GM Y+H RN +HRDL
Sbjct: 618 PPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDL 677
Query: 691 KSDNLLISADRSIKIADFGVARIEVQT-EGMTPETGTYRWMAPEMIQHRPYTQKVDVYSF 515
KS NLL+ ++K+ DFG++R++ T GT WMAPE+++ P +K DVYSF
Sbjct: 678 KSPNLLVDKKYTVKVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSF 737
Query: 514 GIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPC 335
G++LWEL T P+ N+ Q AV + R +P + P + I+ CW +P RP
Sbjct: 738 GVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPS 797
Query: 334 FAEIVNLL 311
FA I++LL
Sbjct: 798 FATIMDLL 805
>sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drkC
OS=Dictyostelium discoideum GN=drkC PE=3 SV=1
Length = 749
Score = 130 bits (325), Expect = 2e-029
Identities = 77/192 (40%), Positives = 109/192 (56%), Gaps = 10/192 (5%)
Frame = -2
Query: 862 PMVLCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVH--ERNFIHRDLK 689
P + IV EY GS+ + L + ++ ALD+A+GM Y+H + IHRDLK
Sbjct: 559 PPEILIVMEYMPLGSLYRIL-HDPSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLK 617
Query: 688 SDNLLISADRSIKIADFGVA-----RIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDV 524
S NLL+ +KI+DFG++ ++ +T MTP GT W APE++++ PYT+K DV
Sbjct: 618 SHNLLVDEHYRVKISDFGLSTRFKKHLDKKT-AMTP-VGTPCWTAPEVLRNDPYTEKADV 675
Query: 523 YSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEV 344
+SF IVLWE++T P+Q M Q +V +RP VP ++T CW DP+
Sbjct: 676 FSFAIVLWEIVTREDPYQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQ 735
Query: 343 RPCFAEIVNLLE 308
RP F EIV LE
Sbjct: 736 RPSFQEIVKRLE 747
>sp|P18161|PYK2_DICDI Dual specificity protein kinase pyk2 OS=Dictyostelium
discoideum GN=splB PE=2 SV=2
Length = 1155
Score = 129 bits (323), Expect = 3e-029
Identities = 65/158 (41%), Positives = 99/158 (62%), Gaps = 4/158 (2%)
Frame = -2
Query: 769 LAVKQALDVARGMAYVHERNFIHRDLKSDNLLISADRSIKIADFGVARIEVQTEGMTPET 590
L +K A D+A G+ ++H +HRDL S N+L+ +IKI+DFG++R + + MT
Sbjct: 953 LVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTN 1012
Query: 589 G---TYRWMAPEMIQH-RPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGV 422
G RW PE+ ++ Y++KVDVY F +V+WE++TG +PF ++ QA+ V G+
Sbjct: 1013 GGICNPRWRPPELTKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQASAQVAYAGL 1072
Query: 421 RPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLE 308
RP +P C P L ++T+CW+ADP RP F IVN L+
Sbjct: 1073 RPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLK 1110
>sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0287001 OS=Dictyostelium discoideum GN=DDB_G0287001 PE=3
SV=1
Length = 650
Score = 123 bits (307), Expect = 2e-027
Identities = 66/179 (36%), Positives = 102/179 (56%), Gaps = 2/179 (1%)
Frame = -2
Query: 844 VTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHERNFIHRDLKSDNLLISA 665
V+E K GS+R L ++ + + + A D+A M ++H IHRDLKS N+LI+
Sbjct: 461 VSELVKSGSLRDLLLDKE-KPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITE 519
Query: 664 DRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITG 485
D + K+ DFG +R + MT GT +M+PE+ + Y + DVY+FGIVLWE+I
Sbjct: 520 DFTAKVIDFGTSRNVDLAKQMTLNLGTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIAR 579
Query: 484 LLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLE 308
P++N+ + +V +G RPT+P DC +++ CW P+ RP F EI + L+
Sbjct: 580 KEPYENINSWSIP-VLVAKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLK 637
>sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0286997 OS=Dictyostelium discoideum GN=DDB_G0286997 PE=3
SV=1
Length = 966
Score = 122 bits (305), Expect = 4e-027
Identities = 66/179 (36%), Positives = 102/179 (56%), Gaps = 2/179 (1%)
Frame = -2
Query: 844 VTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHERNFIHRDLKSDNLLISA 665
V+E K GS+R L ++ + + + A D+A M ++H IHRDLKS N+LI+
Sbjct: 777 VSELVKSGSLRDLLLDKE-KPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITE 835
Query: 664 DRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITG 485
D + K+ DFG +R + MT GT +M+PE+ + Y + DVY+FGIVLWE+I
Sbjct: 836 DFTAKVIDFGTSRNVDLAKHMTMNLGTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIAR 895
Query: 484 LLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLE 308
P++N+ + +V +G RPT+P DC +++ CW P+ RP F EI + L+
Sbjct: 896 KEPYENINSWSIP-VMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLK 953
>sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase DDB_G0282895
OS=Dictyostelium discoideum GN=DDB_G0282895 PE=3 SV=1
Length = 1634
Score = 116 bits (290), Expect = 2e-025
Identities = 61/180 (33%), Positives = 105/180 (58%), Gaps = 3/180 (1%)
Frame = -2
Query: 847 IVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHERNFIHRDLKSDNLLIS 668
IVTE G++ + + K N+ + L+ +K AL VA+G+AY+H +FIHRD+K+ N+L+
Sbjct: 1452 IVTELMHKGTLLEVINK--NKPLSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVD 1509
Query: 667 ADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT 488
+ + K+ DFG++R+ MT GT +W +PE + YT DVYS+G++L+EL T
Sbjct: 1510 KNNNAKVGDFGLSRVIDNNFNMTAVAGTPKWESPECLMGEAYTSASDVYSYGMMLFELAT 1569
Query: 487 GLLPF-QNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLL 311
G PF + + V+ A +V ++ ++P + + ++ C P+ RP +I+ L
Sbjct: 1570 GDEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL 1629
>sp|Q6XHA7|ROCO9_DICDI Probable serine/threonine-protein kinase roco9
OS=Dictyostelium discoideum GN=roco9 PE=3 SV=1
Length = 3365
Score = 109 bits (272), Expect = 3e-023
Identities = 62/202 (30%), Positives = 109/202 (53%), Gaps = 11/202 (5%)
Frame = -2
Query: 871 CIKPMVLCIVTEYAKGGSVRQFLTKRQNRAVPLKLAVKQALDVARGMAYVHER--NFIHR 698
C++P L I+TE+ GG++ ++ +N + +L +K A +A + +H+ + +HR
Sbjct: 3075 CLEP--LAIITEFQSGGNLYDYIHDLKN-PLDWQLRIKIAKGIAASLQTLHDSRPSVVHR 3131
Query: 697 DLKSDNLLISADRSI----KIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKV 530
DLKS N+L+S+ S+ + DF ++ + + W+APE+I + + K
Sbjct: 3132 DLKSPNILLSSKDSLTMECHLCDFSLSGFSTTVANRSVQNPV--WLAPEVINNELCSDKS 3189
Query: 529 DVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADP 350
DVY++G++L+EL++ F N+T + ++ GVRP++P LP ++ CW DP
Sbjct: 3190 DVYAYGVILFELLSRTRFFSNITFMSEVEGLITEGVRPSLPSHNLPEYDSLLNICWAQDP 3249
Query: 349 EVRPCFAEIVNLLEGAETEVMT 284
RP F EI LE E + T
Sbjct: 3250 TCRPSFIEITKKLEEIELILKT 3271
>sp|Q8VDG6|M3KL4_MOUSE Mitogen-activated protein kinase kinase kinase OS=Mus
musculus GN=Mlk4 PE=2 SV=2
Length = 1002
Score = 102 bits (254), Expect = 3e-021
Identities = 47/134 (35%), Positives = 81/134 (60%), Gaps = 1/134 (0%)
Frame = -2
Query: 664 DRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITG 485
++++KI DFG+AR +T M+ GTY WMAPE+I+ +++ D++S+G++LWEL+TG
Sbjct: 266 NKTLKITDFGLAREWHRTTRMS-AAGTYAWMAPEVIRSSLFSKGSDIWSYGVLLWELLTG 324
Query: 484 LLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLEG 305
+P++ + + A+ V + +P C ++M CW+ DP +RP FA I+ L
Sbjct: 325 EVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWEQDPHIRPSFALILQQLTA 384
Query: 304 AETEVMTTVRKARF 263
E V+T + + F
Sbjct: 385 IEEAVLTNMPQESF 398
>sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase kinase OS=Homo
sapiens GN=MLK4 PE=1 SV=1
Length = 1036
Score = 102 bits (253), Expect = 4e-021
Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = -2
Query: 664 DRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITG 485
++++KI DFG+AR +T M+ GTY WMAPE+I+ +++ D++S+G++LWEL+TG
Sbjct: 282 NKTLKITDFGLAREWHRTTKMS-TAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTG 340
Query: 484 LLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLEG 305
+P++ + + A+ V + +P C ++M CW DP +RP FA I+ L
Sbjct: 341 EVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTA 400
Query: 304 AETEVMTTVRKARF 263
E VMT + + F
Sbjct: 401 IEGAVMTEMPQESF 414
>sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo
sapiens GN=MAP3K11 PE=1 SV=1
Length = 847
Score = 102 bits (252), Expect = 5e-021
Identities = 49/133 (36%), Positives = 79/133 (59%), Gaps = 1/133 (0%)
Frame = -2
Query: 661 RSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGL 482
+++KI DFG+AR +T M+ GTY WMAPE+I+ +++ DV+SFG++LWEL+TG
Sbjct: 261 KTLKITDFGLAREWHKTTQMS-AAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGE 319
Query: 481 LPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLEGA 302
+P++ + + A+ V + +P C ++M CW DP RP FA I+ LE
Sbjct: 320 VPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEAL 379
Query: 301 ETEVMTTVRKARF 263
E +V+ + + F
Sbjct: 380 EAQVLREMPRDSF 392
>sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 OS=Mus
musculus GN=Map3k11 PE=1 SV=1
Length = 850
Score = 102 bits (252), Expect = 5e-021
Identities = 49/133 (36%), Positives = 79/133 (59%), Gaps = 1/133 (0%)
Frame = -2
Query: 661 RSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGL 482
+++KI DFG+AR +T M+ GTY WMAPE+I+ +++ DV+SFG++LWEL+TG
Sbjct: 262 KTLKITDFGLAREWHKTTQMS-AAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGE 320
Query: 481 LPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLEGA 302
+P++ + + A+ V + +P C ++M CW DP RP FA I+ LE
Sbjct: 321 VPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEAL 380
Query: 301 ETEVMTTVRKARF 263
E +V+ + + F
Sbjct: 381 EAQVLREMPRDSF 393
>sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase 11 OS=Rattus
norvegicus GN=Map3k11 PE=2 SV=1
Length = 850
Score = 102 bits (252), Expect = 5e-021
Identities = 49/133 (36%), Positives = 79/133 (59%), Gaps = 1/133 (0%)
Frame = -2
Query: 661 RSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGL 482
+++KI DFG+AR +T M+ GTY WMAPE+I+ +++ DV+SFG++LWEL+TG
Sbjct: 262 KTLKITDFGLAREWHKTTQMS-AAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGE 320
Query: 481 LPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLEGA 302
+P++ + + A+ V + +P C ++M CW DP RP FA I+ LE
Sbjct: 321 VPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEAL 380
Query: 301 ETEVMTTVRKARF 263
E +V+ + + F
Sbjct: 381 EAQVLREMPRDSF 393
>sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 OS=Homo
sapiens GN=MAP3K10 PE=1 SV=3
Length = 954
Score = 100 bits (248), Expect = 2e-020
Identities = 49/127 (38%), Positives = 74/127 (58%), Gaps = 1/127 (0%)
Frame = -2
Query: 667 ADRSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT 488
AD +KI DFG+AR +T M+ GTY WMAPE+I+ +++ DV+SFG++LWEL+T
Sbjct: 240 ADTVLKITDFGLAREWHKTTKMS-AAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLT 298
Query: 487 GLLPFQNMTAVQAAFAVVNRGVRPTVPGDCLPVLGEIMTRCWDADPEVRPCFAEIVNLLE 308
G +P++ + A+ A+ V + +P C ++ CWD DP RP F I+ LE
Sbjct: 299 GEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLE 358
Query: 307 GAETEVM 287
E +
Sbjct: 359 VIEQSAL 365
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,405,176,235
Number of Sequences: 518415
Number of Extensions: 82405176235
Number of Successful Extensions: 554174885
Number of sequences better than 0.0: 0
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