BLASTX 7.6.2
Query= UN21059 /QuerySize=1339
(1338 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99J62|RFC4_MOUSE Replication factor C subunit 4 OS=Mus muscu... 357 1e-097
sp|P35249|RFC4_HUMAN Replication factor C subunit 4 OS=Homo sapi... 357 1e-097
sp|Q54MD4|RFC4_DICDI Probable replication factor C subunit 4 OS=... 342 6e-093
sp|P40348|RFC2_YEAST Replication factor C subunit 2 OS=Saccharom... 313 3e-084
sp|Q09843|RFC2_SCHPO Replication factor C subunit 2 OS=Schizosac... 309 4e-083
sp|P53016|RFC4_CAEEL Replication factor C subunit 4 OS=Caenorhab... 230 3e-059
sp|Q5UQ72|RFCS4_MIMIV Putative replication factor C small subuni... 198 1e-049
sp|O28219|RFCS_ARCFU Replication factor C small subunit OS=Archa... 159 4e-038
sp|Q5JHP2|RFCS_PYRKO Replication factor C small subunit OS=Pyroc... 147 3e-034
sp|P0C7N7|RFC2_PHANO Replication factor C subunit 2 OS=Phaeospha... 142 6e-033
sp|A4WGV2|RFCS1_PYRAR Replication factor C small subunit 1 OS=Py... 142 8e-033
sp|Q8U4J3|RFCS_PYRFU Replication factor C small subunit OS=Pyroc... 140 2e-032
sp|O57852|RFCS_PYRHO Replication factor C small subunit OS=Pyroc... 139 4e-032
sp|Q8ZYK4|RFCS1_PYRAE Replication factor C small subunit 1 OS=Py... 139 5e-032
sp|A3DNV9|RFCS_STAMF Replication factor C small subunit OS=Staph... 139 7e-032
sp|A3MS28|RFCS_PYRCJ Replication factor C small subunit OS=Pyrob... 138 9e-032
sp|Q9YBS7|RFCS_AERPE Replication factor C small subunit OS=Aerop... 138 1e-031
sp|A1RSA2|RFCS1_PYRIL Replication factor C small subunit 1 OS=Py... 138 2e-031
sp|P40937|RFC5_HUMAN Replication factor C subunit 5 OS=Homo sapi... 125 1e-027
>sp|Q99J62|RFC4_MOUSE Replication factor C subunit 4 OS=Mus musculus GN=Rfc4
PE=1 SV=1
Length = 364
Score = 357 bits (916), Expect = 1e-097
Identities = 181/326 (55%), Positives = 239/326 (73%), Gaps = 3/326 (0%)
Frame = +1
Query: 100 PWVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQLFGP 279
PWVEKYRPK V +VA Q+EVV VL +LE A+ P++LFYGPPGTGKT+T LA A +LFGP
Sbjct: 39 PWVEKYRPKCVDEVAFQDEVVAVLRKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGP 98
Query: 280 ELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSSNRQGGYPCPSFKIIILDEADSMTE 459
EL++ RVLELNASD+RGI VVR K+K+FA + V S +R G PCP FKI+ILDEADSMT
Sbjct: 99 ELFRLRVLELNASDERGIQVVREKVKNFAQLTV-SGSRSDGKPCPPFKIVILDEADSMTS 157
Query: 460 DAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNE 639
AQ ALRRTME SK TRF ICNY+SRIIEPL SRC+KFRFKPLS+++ R+L I +
Sbjct: 158 AAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQERLLDIAEK 217
Query: 640 EGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLL-NVSGVVPLEVVKRF 816
E + +G E ++ L IS+GDLR+AIT+LQS RL G S D++ +++GV+P +
Sbjct: 218 ENVKIGNEEIAYLVKISEGDLRKAITFLQSATRLTGGKEVSEDVITDIAGVIPAATIDGI 277
Query: 817 FTACRSGDFDIANKEVDNIVAEGYPASQIINQLFDIVVEAGDDITDNQKAKICKCLAETD 996
FTAC SG FD V N++ EG+ A+Q++NQL D ++E ++++D K+ I + LAE D
Sbjct: 278 FTACHSGSFDKLEAVVKNLIDEGHAATQLVNQLHDAIIE-NENLSDKHKSIITEKLAEVD 336
Query: 997 KRLVDGADEYLQLLDVASNTITALSE 1074
K L DGADE+LQL+ + + + L++
Sbjct: 337 KCLADGADEHLQLMSLCATVMQQLTQ 362
>sp|P35249|RFC4_HUMAN Replication factor C subunit 4 OS=Homo sapiens GN=RFC4
PE=1 SV=2
Length = 363
Score = 357 bits (915), Expect = 1e-097
Identities = 183/326 (56%), Positives = 240/326 (73%), Gaps = 4/326 (1%)
Frame = +1
Query: 100 PWVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQLFGP 279
PWVEKYRPK V +VA QEEVV VL +LE A+ P++LFYGPPGTGKT+T LA A +LFGP
Sbjct: 39 PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGP 98
Query: 280 ELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSSNRQGGYPCPSFKIIILDEADSMTE 459
EL++ RVLELNASD+RGI VVR K+K+FA + V S +R G PCP FKI+ILDEADSMT
Sbjct: 99 ELFRLRVLELNASDERGIQVVREKVKNFAQLTV-SGSRSDGKPCPPFKIVILDEADSMTS 157
Query: 460 DAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNE 639
AQ ALRRTME SK TRF ICNY+SRIIEPL SRC+KFRFKPLS+++ R+L I +
Sbjct: 158 AAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKK 217
Query: 640 EGLNLGGEALSTLSIISQGDLRRAITYLQSGARLF-GSTITSTDLLNVSGVVPLEVVKRF 816
E + + E ++ L +S+GDLR+AIT+LQS RL G IT + +++GV+P E +
Sbjct: 218 ENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGV 277
Query: 817 FTACRSGDFDIANKEVDNIVAEGYPASQIINQLFDIVVEAGDDITDNQKAKICKCLAETD 996
F AC+SG FD V +++ EG+ A+Q++NQL D+VVE ++++D QK+ I + LAE D
Sbjct: 278 FAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVE--NNLSDKQKSIITEKLAEVD 335
Query: 997 KRLVDGADEYLQLLDVASNTITALSE 1074
K L DGADE+LQL+ + + + LS+
Sbjct: 336 KCLADGADEHLQLISLCATVMQQLSQ 361
>sp|Q54MD4|RFC4_DICDI Probable replication factor C subunit 4 OS=Dictyostelium
discoideum GN=rfc4 PE=3 SV=1
Length = 347
Score = 342 bits (875), Expect = 6e-093
Identities = 168/328 (51%), Positives = 226/328 (68%), Gaps = 1/328 (0%)
Frame = +1
Query: 88 QSSQPWVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQ 267
+ ++PWV KYRPK V DV++QE+V+ L +L T N PH+LFYGPPGTGKT+T LAIA
Sbjct: 7 KDTEPWVAKYRPKTVDDVSYQEDVISALKKSLNTGNLPHLLFYGPPGTGKTSTILAIAMD 66
Query: 268 LFGPELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSSNRQGGYPCPSFKIIILDEAD 447
++GPEL K RVLELNASD+RGI VVRTKIK+FA AV + P +FK+IILDEAD
Sbjct: 67 IYGPELMKQRVLELNASDERGIEVVRTKIKNFAGYAVNKTTTGTSNPGATFKLIILDEAD 126
Query: 448 SMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILH 627
SMT DAQ ALRRT+ET SK TRF +CNYISRII+PLASRCAKFRFKPL R+
Sbjct: 127 SMTTDAQAALRRTIETTSKTTRFCLLCNYISRIIDPLASRCAKFRFKPLDTVATIERLKF 186
Query: 628 ICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLNVSGVVPLEVV 807
I +EG+ + ++S GD+R+AITYLQS R F + I+ + N++G +P +++
Sbjct: 187 ISQQEGIKCEESVYQAIQVVSNGDMRKAITYLQSAFRFFANKISEDVIYNIAGSLPPQLI 246
Query: 808 KRFFTACRSGDFDIANKEVDNIVAEGYPASQIINQLFDIVVEAGDDITDNQKAKICKCLA 987
K+ C+ FD V +I+A+GYP SQ+I+QLFD V+ D+ +QK+ I +
Sbjct: 247 KQLVDCCKKNSFDRLQSMVQSIIAQGYPVSQVISQLFDYVLTT-KDLNQSQKSHITMKIG 305
Query: 988 ETDKRLVDGADEYLQLLDVASNTITALS 1071
D+ L+DG++E+LQL D++S + L+
Sbjct: 306 NVDRNLIDGSEEFLQLFDLSSYIMKQLN 333
>sp|P40348|RFC2_YEAST Replication factor C subunit 2 OS=Saccharomyces cerevisiae
GN=RFC2 PE=1 SV=1
Length = 353
Score = 313 bits (800), Expect = 3e-084
Identities = 165/325 (50%), Positives = 220/325 (67%), Gaps = 8/325 (2%)
Frame = +1
Query: 91 SSQPWVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQL 270
+ QPWVEKYRPK + +V Q+ V VL TL++AN PHMLFYGPPGTGKT+T LA+ +L
Sbjct: 23 AQQPWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPHMLFYGPPGTGKTSTILALTKEL 82
Query: 271 FGPELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSSNRQG--GYPCPSFKIIILDEA 444
+GP+L KSR+LELNASD+RGI++VR K+K+FA + V ++ YPCP +KIIILDEA
Sbjct: 83 YGPDLMKSRILELNASDERGISIVREKVKNFARLTVSKPSKHDLENYPCPPYKIIILDEA 142
Query: 445 DSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRIL 624
DSMT DAQ+ALRRTMETYS VTRF ICNY++RII+PLASRC+KFRFK L +R+
Sbjct: 143 DSMTADAQSALRRTMETYSGVTRFCLICNYVTRIIDPLASRCSKFRFKALDASNAIDRLR 202
Query: 625 HICNEEGLNLGGEALSTLSIISQGDLRRAITYLQS---GARLF--GSTITSTDLLNVSGV 789
I +E + L + IS GDLRR IT LQS GA+ G ITST + ++GV
Sbjct: 203 FISEQENVKCDDGVLERILDISAGDLRRGITLLQSASKGAQYLGDGKNITSTQVEELAGV 262
Query: 790 VPLEVVKRFFTACRSGDFDIANKEVDNIVAEGYPASQIINQLFDIVVEAGDDITDNQKAK 969
VP +++ +SGDFD K V+ + G+ A+ ++NQL + + D+ N K +
Sbjct: 263 VPHDILIEIVEKVKSGDFDEIKKYVNTFMKSGWSAASVVNQLHEYYI-TNDNFDTNFKNQ 321
Query: 970 ICKCLAETDKRLVDGADEYLQLLDV 1044
I L TD RL +G +E++QLL++
Sbjct: 322 ISWLLFTTDSRLNNGTNEHIQLLNL 346
>sp|Q09843|RFC2_SCHPO Replication factor C subunit 2 OS=Schizosaccharomyces
pombe GN=rfc2 PE=1 SV=1
Length = 340
Score = 309 bits (790), Expect = 4e-083
Identities = 161/323 (49%), Positives = 224/323 (69%), Gaps = 4/323 (1%)
Frame = +1
Query: 88 QSSQPWVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQ 267
+ S PWVE YRPK + V+ QE V+VL TL + N PHMLFYG PGTGKT+T LA++ +
Sbjct: 16 KKSIPWVELYRPKTLDQVSSQESTVQVLKKTLLSNNLPHMLFYGSPGTGKTSTILALSRE 75
Query: 268 LFGPELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSSNRQGGYPCPSFKIIILDEAD 447
LFGP+L KSRVLELNASD+RGI+++R K+K FA V +N+ GYPCP FKIIILDEAD
Sbjct: 76 LFGPQLMKSRVLELNASDERGISIIREKVKSFAKTTV--TNKVDGYPCPPFKIIILDEAD 133
Query: 448 SMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILH 627
SMT+DAQ ALRRTME+Y+++TRF ICNY++RII+PL+SRC+K+RFKPL E M R+
Sbjct: 134 SMTQDAQAALRRTMESYARITRFCLICNYMTRIIDPLSSRCSKYRFKPLDNENMVKRLEF 193
Query: 628 ICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLF-GSTITSTDLLNVSGVVPLEV 804
I ++ +++ ++ L S GD+R+AIT+LQS A L G+ IT + + ++G VP +
Sbjct: 194 IAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLHQGTPITISSVEELAGAVPYNI 253
Query: 805 VKRFFTACRSGDFDIANKEVDNIVAEGYPASQIINQLFDIVVEAGDDITDNQKAKICKCL 984
++ + + ++ AEGY I++QL D++++ + ++ K KI L
Sbjct: 254 IRSLLDTAYTKNVSNIETLSRDVAAEGYSTGIILSQLHDVLLKE-ETLSSPVKYKIFMKL 312
Query: 985 AETDKRLVDGADEYLQLLDVASN 1053
+E DKRL DGADE LQLLD+ S+
Sbjct: 313 SEVDKRLNDGADETLQLLDLLSS 335
>sp|P53016|RFC4_CAEEL Replication factor C subunit 4 OS=Caenorhabditis elegans
GN=rfc-4 PE=1 SV=1
Length = 334
Score = 230 bits (584), Expect = 3e-059
Identities = 134/319 (42%), Positives = 187/319 (58%), Gaps = 17/319 (5%)
Frame = +1
Query: 103 WVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQLFGPE 282
W EKYRPK + D+A+Q+EVV +L L+ + PH+LFYGPPGTGKT+ ALA QLF
Sbjct: 17 WTEKYRPKTLDDIAYQDEVVTMLKGALQGRDLPHLLFYGPPGTGKTSAALAFCRQLFPKN 76
Query: 283 LYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSSNRQGGYPCPSFKIIILDEADSMTED 462
++ RVL+LNASD+RGI VVR KI+ F+ ++G S+R+ KIIILDE D+MT +
Sbjct: 77 IFHDRVLDLNASDERGIAVVRQKIQSFSKSSLGHSHRE---DVLKLKIIILDEVDAMTRE 133
Query: 463 AQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHICNEE 642
AQ A+RR +E +SK TRF ICNY+SR+I P+ SRCAKFRFK L E+ R+ IC+ E
Sbjct: 134 AQAAMRRVIEDFSKTTRFILICNYVSRLIPPVVSRCAKFRFKSLPAEIQVQRLRTICDAE 193
Query: 643 GLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLNVSGVVPLEVVKRFFT 822
G + + L + S+GDLRRA+ LQS A + S + + G ++
Sbjct: 194 GTPMSDDELKQVMEYSEGDLRRAVCTLQSLAPILKSGDDNARNCYLRGSSDSLLIS---N 250
Query: 823 ACRSGDFDIANKEVDNIVA------EGYPASQIINQLFDIVVEAGDDITDNQKAKICKCL 984
C+S I +V I+A + I + F +++ D I D + K +
Sbjct: 251 VCKS----ILTADVPQIIALTKDITKSCTGVAFIRRCFQQLMDE-DVINDENIGVMGKLV 305
Query: 985 AETDKRLVDGADEYLQLLD 1041
A +KR++DG D LLD
Sbjct: 306 ATCEKRILDGCDLENNLLD 324
>sp|Q5UQ72|RFCS4_MIMIV Putative replication factor C small subunit L510
OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R510 PE=3 SV=1
Length = 363
Score = 198 bits (502), Expect = 1e-049
Identities = 100/212 (47%), Positives = 141/212 (66%), Gaps = 1/212 (0%)
Frame = +1
Query: 94 SQPWVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQLF 273
S PW+EKYRPK+++D+ + ++ + N+ + H LFYGPPGTGKT+ LA+ ++F
Sbjct: 6 SVPWIEKYRPKKLEDITQSQNLLDLFKNSTKKGEMTHFLFYGPPGTGKTSAILAMGREIF 65
Query: 274 GPELYKSRVLELNASDDRGINVVRTKIKDFAAVAVGSSNRQGGYPCPSFKIIILDEADSM 453
E +++RV+E NASDDRGIN VR KI + A V + G PS+KIIILDEADSM
Sbjct: 66 -KEHFQNRVIEFNASDDRGINAVREKITNEAKKYVAEIKLEDGTIIPSYKIIILDEADSM 124
Query: 454 TEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLSEEVMSNRILHIC 633
T++AQ+ALR +E YS TRF FICNYI++I + + SRC+ FK LS+E M ++ I
Sbjct: 125 TDEAQDALRVIIEQYSTATRFCFICNYITKITDAIKSRCSSVYFKKLSDECMVEKLNDIS 184
Query: 634 NEEGLNLGGEALSTLSIISQGDLRRAITYLQS 729
+E + L L T+ +S GD+R+AI LQ+
Sbjct: 185 LKESMELPKNILHTIIDVSNGDMRKAIMLLQN 216
>sp|O28219|RFCS_ARCFU Replication factor C small subunit OS=Archaeoglobus
fulgidus GN=rfcS PE=1 SV=1
Length = 319
Score = 159 bits (402), Expect = 4e-038
Identities = 92/214 (42%), Positives = 124/214 (57%), Gaps = 7/214 (3%)
Frame = +1
Query: 397 GGYPCPSFKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAK 576
GG P FKII LDEAD++T DAQ ALRRTME YSK RF CNY+SRIIEP+ SRCA
Sbjct: 99 GGAP---FKIIFLDEADALTADAQAALRRTMEMYSKSCRFILSCNYVSRIIEPIQSRCAV 155
Query: 577 FRFKPLSEEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTI 756
FRFKP+ +E M R+L IC +EG+ + + L L IS GD R+AI LQ GA G +
Sbjct: 156 FRFKPVPKEAMKKRLLEICEKEGVKITEDGLEALIYISGGDFRKAINALQ-GAAAIGEVV 214
Query: 757 TSTDLLNVSGVVPLEVVKRFFTACRSGDFDIANKEVDNIVAE-GYPASQIINQLFDIVVE 933
+ + ++ E + G+F A + +D ++ E G I+ QLF ++
Sbjct: 215 DADTIYQITATARPEEMTELIQTALKGNFMEARELLDRLMVEYGMSGEDIVAQLFREIIS 274
Query: 934 AGDDITDNQKAKICKCLAETDKRLVDGADEYLQL 1035
I D+ K ++ L E D RL +GA+E +QL
Sbjct: 275 M--PIKDSLKVQLIDKLGEVDFRLTEGANERIQL 306
>sp|Q5JHP2|RFCS_PYRKO Replication factor C small subunit OS=Pyrococcus
kodakaraensis GN=rfcS PE=1 SV=1
Length = 866
Score = 147 bits (369), Expect = 3e-034
Identities = 86/208 (41%), Positives = 126/208 (60%), Gaps = 4/208 (1%)
Frame = +1
Query: 415 SFKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPL 594
SFKII LDEAD++T+DAQ ALRRTME +S RF CNY S+IIEP+ SRCA FRF+PL
Sbjct: 650 SFKIIFLDEADALTQDAQQALRRTMEMFSNNVRFILSCNYSSKIIEPIQSRCAIFRFRPL 709
Query: 595 SEEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLL 774
+E ++ RI +I EGL L E L + +++GDLRRAI LQ+ A L + IT ++
Sbjct: 710 RDEDIAKRIRYIAENEGLELTEEGLQAILYVAEGDLRRAINVLQAAAAL-DTKITDENVF 768
Query: 775 NVSGVVPLEVVKRFFTACRSGDFDIANKEV-DNIVAEGYPASQIINQLFDIVVEAGDDIT 951
V+ E V+ T G+F A +++ D ++ +G ++ Q+ V I
Sbjct: 769 LVASRARPEDVREMMTLALEGNFLKAREKLRDILLRQGLSGEDVLIQMHKEVFNL--PIP 826
Query: 952 DNQKAKICKCLAETDKRLVDGADEYLQL 1035
+++K + + E + RLV+GA+E +QL
Sbjct: 827 EDKKVALADKIGEYNFRLVEGANEMIQL 854
>sp|P0C7N7|RFC2_PHANO Replication factor C subunit 2 OS=Phaeosphaeria nodorum
GN=RFC2 PE=3 SV=1
Length = 411
Score = 142 bits (357), Expect = 6e-033
Identities = 70/120 (58%), Positives = 89/120 (74%)
Frame = +1
Query: 403 YPCPSFKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFR 582
Y CP FKII+LDEADSMT+DAQ+ALRRTMETYS++TRF +CNY++RII+PLASRC+KFR
Sbjct: 153 YSCPPFKIIVLDEADSMTQDAQSALRRTMETYSRMTRFCLVCNYVTRIIDPLASRCSKFR 212
Query: 583 FKPLSEEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITS 762
FK L + R+ I E + L L ++ GDLR+AIT+LQS ARL G+T T+
Sbjct: 213 FKSLDQGNAVRRVDDIAKLEDVKLDAGVSEELVRVADGDLRKAITFLQSAARLVGATQTA 272
Score = 138 bits (346), Expect = 1e-031
Identities = 61/90 (67%), Positives = 78/90 (86%)
Frame = +1
Query: 97 QPWVEKYRPKQVKDVAHQEEVVRVLTNTLETANCPHMLFYGPPGTGKTTTALAIAHQLFG 276
QPWVEKYRPK + +V Q+ +++L+ TL+++N PHMLFYGPPGTGKT+T LA+A QL+G
Sbjct: 33 QPWVEKYRPKTLSEVTAQDNTIQILSRTLQSSNLPHMLFYGPPGTGKTSTILALAKQLYG 92
Query: 277 PELYKSRVLELNASDDRGINVVRTKIKDFA 366
PEL KSRVLELNASD+RGI++VR K+KDFA
Sbjct: 93 PELMKSRVLELNASDERGISIVRQKVKDFA 122
>sp|A4WGV2|RFCS1_PYRAR Replication factor C small subunit 1 OS=Pyrobaculum
arsenaticum (strain DSM 13514 / JCM 11321) GN=rfcS1 PE=3 SV=1
Length = 329
Score = 142 bits (356), Expect = 8e-033
Identities = 82/212 (38%), Positives = 122/212 (57%), Gaps = 4/212 (1%)
Frame = +1
Query: 418 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLS 597
FK++ILDEAD+MT DAQ ALRR ME Y++ TRF + NY+SRII+P+ SRCA FRF P+
Sbjct: 102 FKLVILDEADNMTSDAQQALRRIMEMYAQNTRFILLANYVSRIIDPIISRCAVFRFSPMP 161
Query: 598 EEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLN 777
+M+ R+ HI EG+ L +A+ + +S+GD+R+AI LQ A +
Sbjct: 162 RSLMAERLRHIAKSEGIELRDDAIDLIYEVSEGDMRKAINLLQVAAATSKVVDANAVASA 221
Query: 778 VSGVVPLEVVKRFFTACRSGDFDIANKEVDNIV-AEGYPASQIINQLFDIVVEAGDDITD 954
+ + P +VV+ F +GD A +++ ++ +G I ++ + D
Sbjct: 222 TTMIRPADVVE-LFNLAFNGDVTKAREKLRELMYVKGIAGIDFIRAFQRELIRM--PLDD 278
Query: 955 NQKAKICKCLAETDKRLVDGADEYLQLLDVAS 1050
KA+I + LAE D RL G+DE LQLL + S
Sbjct: 279 EVKAEIAELLAEVDYRLTQGSDEELQLLYLLS 310
>sp|Q8U4J3|RFCS_PYRFU Replication factor C small subunit OS=Pyrococcus furiosus
GN=rfcS PE=1 SV=1
Length = 852
Score = 140 bits (352), Expect = 2e-032
Identities = 83/208 (39%), Positives = 122/208 (58%), Gaps = 4/208 (1%)
Frame = +1
Query: 415 SFKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPL 594
SFKII LDEAD++T+DAQ ALRRTME +S RF CNY S+IIEP+ SRCA FRF+PL
Sbjct: 635 SFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPL 694
Query: 595 SEEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLL 774
+E ++ R+ +I EGL L E L + I++GD+RRAI LQ+ A L IT ++
Sbjct: 695 RDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAAL-DKKITDENVF 753
Query: 775 NVSGVVPLEVVKRFFTACRSGDFDIANKEVDNI-VAEGYPASQIINQLFDIVVEAGDDIT 951
V+ E ++ G+F A +++ I + +G ++ Q+ V I
Sbjct: 754 MVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGEDVLVQMHKEVFNL--PIE 811
Query: 952 DNQKAKICKCLAETDKRLVDGADEYLQL 1035
+ +K + + E + RLV+GA+E +QL
Sbjct: 812 EPKKVLLADKIGEYNFRLVEGANEIIQL 839
>sp|O57852|RFCS_PYRHO Replication factor C small subunit OS=Pyrococcus
horikoshii GN=rfcS PE=3 SV=1
Length = 855
Score = 139 bits (350), Expect = 4e-032
Identities = 83/208 (39%), Positives = 121/208 (58%), Gaps = 4/208 (1%)
Frame = +1
Query: 415 SFKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPL 594
SFKII LDEAD++T+DAQ ALRRTME +S RF CNY S+IIEP+ SRCA FRF+PL
Sbjct: 637 SFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPL 696
Query: 595 SEEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLL 774
+E ++ R+ +I EGL L E L + I++GD+RRAI LQ+ A L IT ++
Sbjct: 697 RDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAAL-DKKITDENVF 755
Query: 775 NVSGVVPLEVVKRFFTACRSGDFDIANKEVDNI-VAEGYPASQIINQLFDIVVEAGDDIT 951
V+ E ++ G+F A +++ I + +G ++ Q+ V I
Sbjct: 756 MVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGEDVLIQMHKEVFNL--PID 813
Query: 952 DNQKAKICKCLAETDKRLVDGADEYLQL 1035
+ K + + E + RLV+GA+E +QL
Sbjct: 814 EPTKVYLADKIGEYNFRLVEGANEMIQL 841
>sp|Q8ZYK4|RFCS1_PYRAE Replication factor C small subunit 1 OS=Pyrobaculum
aerophilum GN=rfcS1 PE=3 SV=1
Length = 329
Score = 139 bits (349), Expect = 5e-032
Identities = 81/207 (39%), Positives = 122/207 (58%), Gaps = 4/207 (1%)
Frame = +1
Query: 418 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLS 597
FK++ILDEAD+MT DAQ ALRR ME Y++ TRF + NY+SRII+P+ SRCA FRF P+
Sbjct: 102 FKLVILDEADNMTSDAQQALRRIMEIYAQNTRFILLANYVSRIIDPIISRCAVFRFSPMP 161
Query: 598 EEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLN 777
+M+ R+ I EG+ L +A++ + +S+GD+R+AI LQ A +
Sbjct: 162 RSLMAERLKFIAKNEGVELREDAINMIYELSEGDMRKAINLLQVAAATNKVVDANAVASA 221
Query: 778 VSGVVPLEVVKRFFTACRSGDFDIANKEVDNIV-AEGYPASQIINQLFDIVVEAGDDITD 954
V P ++++ F A SGDF A +++ ++ +G + I ++ I D
Sbjct: 222 AIAVRPADIIELFNLAI-SGDFVKAREKLRELMYLKGIAGADFIRAFQRELIRM--PIDD 278
Query: 955 NQKAKICKCLAETDKRLVDGADEYLQL 1035
+ KA+I + LA+ D RL GADE +QL
Sbjct: 279 DIKAEIAELLADVDYRLTQGADEEIQL 305
>sp|A3DNV9|RFCS_STAMF Replication factor C small subunit OS=Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1) GN=rfcS PE=3 SV=1
Length = 329
Score = 139 bits (348), Expect = 7e-032
Identities = 80/207 (38%), Positives = 118/207 (57%), Gaps = 3/207 (1%)
Frame = +1
Query: 418 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLS 597
FKI++LDEAD+MT DAQ ALRR ME Y+ TRF I NY S+IIEP+ SRCA FRF PL
Sbjct: 109 FKIVLLDEADNMTADAQQALRRLMEMYTATTRFILIANYPSKIIEPIQSRCAVFRFAPLK 168
Query: 598 EEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLN 777
+E + +R+ I +E + + EAL + +S+GD+RRAI LQ+ A L +T +
Sbjct: 169 KEDVISRLKWIAEQEKVEIDEEALEAIHDLSEGDMRRAINILQAAAAL--GKVTVDSVYK 226
Query: 778 VSGVVPLEVVKRFFTACRSGDFDIANKEVDNIVAE-GYPASQIINQLFDIVVEAGDDITD 954
V G+ +++ +G+F+ A +++ ++ G +I Q+ + I D
Sbjct: 227 VVGLAHPREIRQMIQLALAGNFNDAREKLRELMINYGLSGVDVIKQVHREIFSTDIKIPD 286
Query: 955 NQKAKICKCLAETDKRLVDGADEYLQL 1035
K I E RLV+GAD+ +QL
Sbjct: 287 EFKIIIADLAGEIQFRLVEGADDEIQL 313
>sp|A3MS28|RFCS_PYRCJ Replication factor C small subunit OS=Pyrobaculum
calidifontis (strain JCM 11548 / VA1) GN=rfcS PE=3 SV=1
Length = 326
Score = 138 bits (347), Expect = 9e-032
Identities = 77/208 (37%), Positives = 119/208 (57%), Gaps = 4/208 (1%)
Frame = +1
Query: 418 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLS 597
FK++ILDEAD+MT DAQ ALRR ME Y++ TRF + NY+SRII+P+ SRCA FRF P+
Sbjct: 102 FKLVILDEADNMTSDAQQALRRIMEIYAQNTRFILLANYVSRIIDPIISRCAVFRFSPMP 161
Query: 598 EEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLN 777
+M+ R+ I EG+ L +A+ + IS+GD+R+AI LQ A + + + + +
Sbjct: 162 RHLMAERLREIARSEGVELKDDAIDLIYEISEGDMRKAINLLQVAAAV-SKVVDANAVAS 220
Query: 778 VSGVVPLEVVKRFFTACRSGDFDIANKEVDNIV-AEGYPASQIINQLFDIVVEAGDDITD 954
+ V V F GD A ++ ++ +G +I ++ + D
Sbjct: 221 AAAAVRPSDVLELFNLAMGGDLAKARDKLRELMYIKGVAGVDLIRVFQRELIRM--QLDD 278
Query: 955 NQKAKICKCLAETDKRLVDGADEYLQLL 1038
+ KA++ + L+E D RL GADE +QL+
Sbjct: 279 DVKAEVAELLSEVDYRLTQGADEEIQLM 306
>sp|Q9YBS7|RFCS_AERPE Replication factor C small subunit OS=Aeropyrum pernix
GN=rfcS PE=3 SV=3
Length = 325
Score = 138 bits (346), Expect = 1e-031
Identities = 80/207 (38%), Positives = 116/207 (56%), Gaps = 3/207 (1%)
Frame = +1
Query: 418 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLS 597
FKI++LDEAD+MT DAQ ALRR ME YS VTRF I NY S+II+P+ SRCA FRF+PLS
Sbjct: 105 FKIVLLDEADNMTSDAQQALRRLMELYSSVTRFILIANYPSKIIDPIQSRCAFFRFQPLS 164
Query: 598 EEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLN 777
++ + R+ +I EG++ EAL + IS+GD+R+AI LQ+ + L +T +
Sbjct: 165 KQDVIERLRYIAENEGVDYEEEALDAIYEISEGDMRKAINVLQAASYL--GKVTVDAVYR 222
Query: 778 VSGVVPLEVVKRFFTACRSGDFDIANKEVDNIVAE-GYPASQIINQLFDIVVEAGDDITD 954
V G+ V+ GDF A + I+ E G + Q+ + + +
Sbjct: 223 VVGMAKPREVREMLATALKGDFTAARSLLRKIMIEYGMSGEDVARQIHRELFSTELKMPE 282
Query: 955 NQKAKICKCLAETDKRLVDGADEYLQL 1035
+ L E RLV+G+D+ +QL
Sbjct: 283 ELRVLAADYLGEVHYRLVEGSDDDIQL 309
>sp|A1RSA2|RFCS1_PYRIL Replication factor C small subunit 1 OS=Pyrobaculum
islandicum (strain DSM 4184 / JCM 9189) GN=rfcS1 PE=3 SV=1
Length = 329
Score = 138 bits (345), Expect = 2e-031
Identities = 77/207 (37%), Positives = 120/207 (57%), Gaps = 4/207 (1%)
Frame = +1
Query: 418 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLS 597
FK++ILDEAD+MT DAQ ALRR ME Y++ TRF + NY+SRII+P+ SRCA FRF P+
Sbjct: 102 FKLVILDEADNMTSDAQQALRRIMEIYAQNTRFILLANYVSRIIDPIISRCAVFRFSPMP 161
Query: 598 EEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLN 777
+M+ R+ +I EG+ + +A+ + +S+GD+R+AI LQ A +
Sbjct: 162 RHLMAERLKYIAKSEGVEVKEDAIDLIYELSEGDMRKAINILQVAAATNKIVDRNVVAAA 221
Query: 778 VSGVVPLEVVKRFFTACRSGDFDIANKEVDNIV-AEGYPASQIINQLFDIVVEAGDDITD 954
+ + P ++V+ F SGD+ A +++ ++ +G I ++ D D
Sbjct: 222 AAAIRPTDIVE-LFNLALSGDYLKAREKMRELMYVKGVAGVDFIRAFQRELIRMSLD--D 278
Query: 955 NQKAKICKCLAETDKRLVDGADEYLQL 1035
KA++ + LA+ D RL GADE +QL
Sbjct: 279 ETKAEVAELLADVDYRLTQGADEEIQL 305
>sp|P40937|RFC5_HUMAN Replication factor C subunit 5 OS=Homo sapiens GN=RFC5
PE=1 SV=1
Length = 340
Score = 125 bits (312), Expect = 1e-027
Identities = 72/207 (34%), Positives = 115/207 (55%), Gaps = 4/207 (1%)
Frame = +1
Query: 418 FKIIILDEADSMTEDAQNALRRTMETYSKVTRFFFICNYISRIIEPLASRCAKFRFKPLS 597
FK++ILDEAD+MT+DAQNALRR +E +++ TRF ICNY+S+II L SRC +FRF PL+
Sbjct: 119 FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLT 178
Query: 598 EEVMSNRILHICNEEGLNLGGEALSTLSIISQGDLRRAITYLQSGARLFGSTITSTDLLN 777
E+M R+ H+ EE +++ + + L +S GD+RRA+ LQS FG +T +
Sbjct: 179 PELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGK-VTEETVYT 237
Query: 778 VSGVVPLEVVKRFFTACRSGDFDIANKEVDNI-VAEGYPASQIINQLFDIVVEAGDDITD 954
+G + + DF A + + + +G I+ ++ V D
Sbjct: 238 CTGHPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRV--DFPS 295
Query: 955 NQKAKICKCLAETDKRLVDGADEYLQL 1035
+ + + +A+ + RL G +E +QL
Sbjct: 296 SVRIHLLTKMADIEYRLSVGTNEKIQL 322
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,924,390,942
Number of Sequences: 518415
Number of Extensions: 86924390942
Number of Successful Extensions: 587655121
Number of sequences better than 0.0: 0
|
