BLASTX 7.6.2
Query= UN21248 /QuerySize=892
(891 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54Q31|PHB2_DICDI Prohibitin-2 OS=Dictyostelium discoideum GN... 230 1e-059
sp|P50085|PHB2_YEAST Prohibitin-2 OS=Saccharomyces cerevisiae GN... 218 4e-056
sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex protein 2 ... 217 1e-055
sp|O94550|PHB2_SCHPO Prohibitin-2 OS=Schizosaccharomyces pombe G... 216 2e-055
sp|Q99623|PHB2_HUMAN Prohibitin-2 OS=Homo sapiens GN=PHB2 PE=1 SV=2 206 2e-052
sp|O35129|PHB2_MOUSE Prohibitin-2 OS=Mus musculus GN=Phb2 PE=1 SV=1 206 2e-052
sp|Q5RB19|PHB2_PONAB Prohibitin-2 OS=Pongo abelii GN=PHB2 PE=2 SV=1 206 2e-052
sp|Q5XIH7|PHB2_RAT Prohibitin-2 OS=Rattus norvegicus GN=Phb2 PE=... 206 2e-052
sp|Q2HJ97|PHB2_BOVIN Prohibitin-2 OS=Bos taurus GN=PHB2 PE=2 SV=1 205 3e-052
sp|A9UMS3|PHB2_XENTR Prohibitin-2 OS=Xenopus tropicalis GN=phb2 ... 205 3e-052
sp|P24156|L2CC_DROME Protein l(2)37Cc OS=Drosophila melanogaster... 203 1e-051
sp|Q5ZMN3|PHB2_CHICK Prohibitin-2 OS=Gallus gallus GN=PHB2 PE=2 ... 202 4e-051
sp|Q9P7H3|PHB1_SCHPO Prohibitin-1 OS=Schizosaccharomyces pombe G... 197 1e-049
sp|P67778|PHB_MOUSE Prohibitin OS=Mus musculus GN=Phb PE=1 SV=1 197 1e-049
sp|P67779|PHB_RAT Prohibitin OS=Rattus norvegicus GN=Phb PE=1 SV=1 197 1e-049
sp|Q54GI9|PHB1_DICDI Prohibitin-1, mitochondrial OS=Dictyosteliu... 196 2e-049
sp|Q3T165|PHB_BOVIN Prohibitin OS=Bos taurus GN=PHB PE=2 SV=1 195 4e-049
sp|P35232|PHB_HUMAN Prohibitin OS=Homo sapiens GN=PHB PE=1 SV=1 195 4e-049
sp|P84173|PHB_CHICK Prohibitin OS=Gallus gallus GN=PHB PE=1 SV=1 193 2e-048
sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex protein 1 ... 190 1e-047
>sp|Q54Q31|PHB2_DICDI Prohibitin-2 OS=Dictyostelium discoideum GN=phbB PE=3
SV=1
Length = 293
Score = 230 bits (585), Expect = 1e-059
Identities = 129/244 (52%), Positives = 171/244 (70%), Gaps = 5/244 (2%)
Frame = +3
Query: 108 EMSFNKVPNVPGSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVY 287
+++FN +P +P + + +GG+G+ AL +SL NVEGGHRA++FNR GIK KVY
Sbjct: 7 QVNFNNIPKLP-KGSFGGGFGLLALGGVGLLAL-SSLVNVEGGHRAIVFNRFVGIKNKVY 64
Query: 288 PEGTHFMLPWFERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTL 467
EGTHF++PWFER IYDVRA+P + S TGS DLQMV + +RVL++P +LP IYRTL
Sbjct: 65 NEGTHFIVPWFERAEIYDVRAKPRSISSLTGSKDLQMVNITIRVLSKPKVSQLPAIYRTL 124
Query: 468 GENYSERVLPSIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSI 647
G++Y ERVLPSI++E LK++VAQ+NASQLITQRE VSR I K L +RA +F+I LDDVSI
Sbjct: 125 GKDYDERVLPSIVNEILKSIVAQFNASQLITQREQVSRLIFKRLVDRAKDFNIELDDVSI 184
Query: 648 TTLTFGKEFTAAIEANKSLLRR*TC*VHCGESRARQEKCS--HPCGGRS*SAQLIGQAIA 821
T L FG+E+ AAIEA K + ++ +A Q+K S G + SAQLI AI
Sbjct: 185 THLNFGREYAAAIEA-KQVAQQEAERARFLVEKALQDKRSIIVKAEGEAQSAQLINDAIK 243
Query: 822 NNQH 833
+ +
Sbjct: 244 QSPY 247
>sp|P50085|PHB2_YEAST Prohibitin-2 OS=Saccharomyces cerevisiae GN=PHB2 PE=1
SV=2
Length = 310
Score = 218 bits (555), Expect = 4e-056
Identities = 123/238 (51%), Positives = 167/238 (70%), Gaps = 6/238 (2%)
Frame = +3
Query: 123 KVPNVPGSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTH 302
+VP+ G A + L + ++GG G + N+L+NV+GGHRA++++R+ G+ +++ EGTH
Sbjct: 30 QVPSPRG--AFAGLGGLLLLGG-GALFINNALFNVDGGHRAIVYSRIHGVSSRIFNEGTH 86
Query: 303 FMLPWFERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYS 482
F+ PW + PIIYDVRA+P V S TG+ DLQMV + RVL+RP +LP IYRTLG++Y
Sbjct: 87 FIFPWLDTPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYD 146
Query: 483 ERVLPSIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTF 662
ERVLPSI++E LKAVVAQ+NASQLITQRE VSR IR+ L RAS F+I LDDVSIT +TF
Sbjct: 147 ERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRASKFNILLDDVSITYMTF 206
Query: 663 GKEFTAAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANNQ 830
EFT A+EA K + ++ +ARQEK G + SA+LIG+AI ++
Sbjct: 207 SPEFTNAVEA-KQIAQQDAQRAAFVVDKARQEKQGMVVRAQGEAKSAELIGEAIKKSR 263
>sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex protein 2
OS=Caenorhabditis elegans GN=phb-2 PE=1 SV=2
Length = 294
Score = 217 bits (551), Expect = 1e-055
Identities = 113/216 (52%), Positives = 151/216 (69%), Gaps = 3/216 (1%)
Frame = +3
Query: 186 GLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDVRARPYLV 365
G VY + S++ VE GHRA+MFNR+ G+ +Y EG HF +PWF+ PIIYD+RARP +
Sbjct: 30 GAAVYGVAQSMFTVEAGHRAIMFNRIGGLSTDLYKEGLHFRIPWFQYPIIYDIRARPNQI 89
Query: 366 ESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKAVVAQYNA 545
S TGS DLQMV +GLRVL+RP + L HIYRTLG+N+ ERVLPSI +E LK VVA++NA
Sbjct: 90 RSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYRTLGQNWEERVLPSICNEVLKGVVAKFNA 149
Query: 546 SQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEANKSLLRR*TC* 725
SQLITQR+ VS +RK L ERA +F+I LDDVS+T L F +++AA+EA K + +
Sbjct: 150 SQLITQRQQVSMLVRKTLIERALDFNIILDDVSLTELAFSPQYSAAVEA-KQVAAQEAQR 208
Query: 726 VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
RA+Q+K G + SA+L+G+A+ N+
Sbjct: 209 ATFYVERAKQQKQEKIVQAEGEAESAKLLGEAMKND 244
>sp|O94550|PHB2_SCHPO Prohibitin-2 OS=Schizosaccharomyces pombe GN=phb2 PE=2
SV=1
Length = 279
Score = 216 bits (549), Expect = 2e-055
Identities = 117/215 (54%), Positives = 151/215 (70%), Gaps = 3/215 (1%)
Frame = +3
Query: 186 GLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDVRARPYLV 365
GL +A+ SL+NV+GGHRA+ ++R+ GIK +YPEGTHF++PW E I YDVRA+P +
Sbjct: 26 GLAGFAVQTSLFNVDGGHRAIKYSRIGGIKNLIYPEGTHFLIPWIETAIDYDVRAKPRNI 85
Query: 366 ESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKAVVAQYNA 545
S TG+ DLQMV + RVL+RP LP IYRTLG +Y ERVLPSI++E LK+VVAQ+NA
Sbjct: 86 SSLTGTKDLQMVNINCRVLSRPDVHALPKIYRTLGGDYDERVLPSIVNEVLKSVVAQFNA 145
Query: 546 SQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEANKSLLRR*TC* 725
SQLITQRE VSR +R+ L +RA+ F+I LDDVS+T + F EFTAA+EA K + ++
Sbjct: 146 SQLITQRERVSRLVRENLMKRAARFNILLDDVSLTHVQFSPEFTAAVEA-KQIAQQDAQR 204
Query: 726 VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIAN 824
RAR EK G +AQLIG+AI N
Sbjct: 205 ATFYVDRARMEKQGFIVRAQGEGRAAQLIGEAIKN 239
>sp|Q99623|PHB2_HUMAN Prohibitin-2 OS=Homo sapiens GN=PHB2 PE=1 SV=2
Length = 299
Score = 206 bits (523), Expect = 2e-052
Identities = 109/232 (46%), Positives = 157/232 (67%), Gaps = 4/232 (1%)
Frame = +3
Query: 141 GSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGI-KEKVYPEGTHFMLPW 317
G + LK+ + G Y + S++ VEGGHRA+ FNR+ G+ ++ + EG HF +PW
Sbjct: 15 GPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPW 74
Query: 318 FERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLP 497
F+ PIIYD+RARP + S TGS DLQMV + LRVL+RP LP +Y+ LG +Y ERVLP
Sbjct: 75 FQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLP 134
Query: 498 SIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFT 677
SI++E LK+VVA++NASQLITQR VS IR+ LTERA +F + LDDV+IT L+F +E+T
Sbjct: 135 SIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYT 194
Query: 678 AAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
AA+EA K + ++ +A+QE+ G + +A+++G+A++ N
Sbjct: 195 AAVEA-KQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKN 245
>sp|O35129|PHB2_MOUSE Prohibitin-2 OS=Mus musculus GN=Phb2 PE=1 SV=1
Length = 299
Score = 206 bits (523), Expect = 2e-052
Identities = 109/232 (46%), Positives = 157/232 (67%), Gaps = 4/232 (1%)
Frame = +3
Query: 141 GSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGI-KEKVYPEGTHFMLPW 317
G + LK+ + G Y + S++ VEGGHRA+ FNR+ G+ ++ + EG HF +PW
Sbjct: 15 GPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPW 74
Query: 318 FERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLP 497
F+ PIIYD+RARP + S TGS DLQMV + LRVL+RP LP +Y+ LG +Y ERVLP
Sbjct: 75 FQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLP 134
Query: 498 SIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFT 677
SI++E LK+VVA++NASQLITQR VS IR+ LTERA +F + LDDV+IT L+F +E+T
Sbjct: 135 SIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYT 194
Query: 678 AAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
AA+EA K + ++ +A+QE+ G + +A+++G+A++ N
Sbjct: 195 AAVEA-KQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKN 245
>sp|Q5RB19|PHB2_PONAB Prohibitin-2 OS=Pongo abelii GN=PHB2 PE=2 SV=1
Length = 299
Score = 206 bits (523), Expect = 2e-052
Identities = 109/232 (46%), Positives = 157/232 (67%), Gaps = 4/232 (1%)
Frame = +3
Query: 141 GSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGI-KEKVYPEGTHFMLPW 317
G + LK+ + G Y + S++ VEGGHRA+ FNR+ G+ ++ + EG HF +PW
Sbjct: 15 GPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPW 74
Query: 318 FERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLP 497
F+ PIIYD+RARP + S TGS DLQMV + LRVL+RP LP +Y+ LG +Y ERVLP
Sbjct: 75 FQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLP 134
Query: 498 SIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFT 677
SI++E LK+VVA++NASQLITQR VS IR+ LTERA +F + LDDV+IT L+F +E+T
Sbjct: 135 SIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYT 194
Query: 678 AAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
AA+EA K + ++ +A+QE+ G + +A+++G+A++ N
Sbjct: 195 AAVEA-KQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKN 245
>sp|Q5XIH7|PHB2_RAT Prohibitin-2 OS=Rattus norvegicus GN=Phb2 PE=1 SV=1
Length = 299
Score = 206 bits (523), Expect = 2e-052
Identities = 109/232 (46%), Positives = 157/232 (67%), Gaps = 4/232 (1%)
Frame = +3
Query: 141 GSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGI-KEKVYPEGTHFMLPW 317
G + LK+ + G Y + S++ VEGGHRA+ FNR+ G+ ++ + EG HF +PW
Sbjct: 15 GPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPW 74
Query: 318 FERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLP 497
F+ PIIYD+RARP + S TGS DLQMV + LRVL+RP LP +Y+ LG +Y ERVLP
Sbjct: 75 FQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLP 134
Query: 498 SIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFT 677
SI++E LK+VVA++NASQLITQR VS IR+ LTERA +F + LDDV+IT L+F +E+T
Sbjct: 135 SIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYT 194
Query: 678 AAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
AA+EA K + ++ +A+QE+ G + +A+++G+A++ N
Sbjct: 195 AAVEA-KQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKN 245
>sp|Q2HJ97|PHB2_BOVIN Prohibitin-2 OS=Bos taurus GN=PHB2 PE=2 SV=1
Length = 299
Score = 205 bits (521), Expect = 3e-052
Identities = 109/232 (46%), Positives = 157/232 (67%), Gaps = 4/232 (1%)
Frame = +3
Query: 141 GSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGI-KEKVYPEGTHFMLPW 317
G + LK+ + G Y + S++ VEGGHRA+ FNR+ G+ ++ + EG HF +PW
Sbjct: 15 GPRGMGTALKLLLGAGAVAYGIRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPW 74
Query: 318 FERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLP 497
F+ PIIYD+RARP + S TGS DLQMV + LRVL+RP LP +Y+ LG +Y ERVLP
Sbjct: 75 FQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAMELPSMYQRLGLDYEERVLP 134
Query: 498 SIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFT 677
SI++E LK+VVA++NASQLITQR VS IR+ LTERA +F + LDDV+IT L+F +E+T
Sbjct: 135 SIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYT 194
Query: 678 AAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
AA+EA K + ++ +A+QE+ G + +A+++G+A++ N
Sbjct: 195 AAVEA-KQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAARMLGEALSKN 245
>sp|A9UMS3|PHB2_XENTR Prohibitin-2 OS=Xenopus tropicalis GN=phb2 PE=2 SV=1
Length = 301
Score = 205 bits (521), Expect = 3e-052
Identities = 109/232 (46%), Positives = 157/232 (67%), Gaps = 4/232 (1%)
Frame = +3
Query: 141 GSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGI-KEKVYPEGTHFMLPW 317
G + +K+ + G YA+ S++ VEGGHRA+ FNR+ G+ ++ + EG HF PW
Sbjct: 15 GPRGMGTAMKLLLGAGAVAYAVKESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRFPW 74
Query: 318 FERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLP 497
F+ PIIYD+RARP + S TGS DLQMV + LRVL+RP+ LP +Y+ LG +Y ERVLP
Sbjct: 75 FQYPIIYDIRARPRKISSPTGSKDLQMVNITLRVLSRPLASELPFMYQRLGLDYDERVLP 134
Query: 498 SIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFT 677
SI++E LK+VVA++NASQLITQR VS IR+ LTERA +F I LDDV+IT L+F +E+T
Sbjct: 135 SIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSIILDDVAITELSFSREYT 194
Query: 678 AAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
AA+E +K + ++ +A+Q++ G + +A++IG A++ N
Sbjct: 195 AAVE-SKQVAQQEAQRAQFLVEKAKQDQKQKIVQAEGEAAAAKMIGDALSKN 245
>sp|P24156|L2CC_DROME Protein l(2)37Cc OS=Drosophila melanogaster GN=l(2)37Cc
PE=1 SV=2
Length = 276
Score = 203 bits (516), Expect = 1e-051
Identities = 102/175 (58%), Positives = 132/175 (75%), Gaps = 4/175 (2%)
Frame = +3
Query: 165 LKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDV 344
L V+V+GG+ + ++LYNVEGGHRAV+F+R TGIKE V EGTHF +PW +RPII+D+
Sbjct: 14 LGVAVLGGV----VNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDI 69
Query: 345 RARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKA 524
R++P V TGS DLQ V + LR+L RP+ D+LP IY LG++Y ERVLPSI E LKA
Sbjct: 70 RSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKA 129
Query: 525 VVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIE 689
VVAQ++A +LITQRE VS+ + + LT RA F LDD+S+T LTFG+EFT A+E
Sbjct: 130 VVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVE 184
>sp|Q5ZMN3|PHB2_CHICK Prohibitin-2 OS=Gallus gallus GN=PHB2 PE=2 SV=1
Length = 301
Score = 202 bits (512), Expect = 4e-051
Identities = 109/232 (46%), Positives = 156/232 (67%), Gaps = 4/232 (1%)
Frame = +3
Query: 141 GSPALSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGI-KEKVYPEGTHFMLPW 317
G + LK+ + G Y + S++ VEGG RA+ FNR+ G+ ++ + EG HF +PW
Sbjct: 15 GPRGVGTALKLLLGAGALAYGVRESVFIVEGGQRAIFFNRIGGVQQDTILAEGLHFRIPW 74
Query: 318 FERPIIYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLP 497
F+ PIIYD+RARP + S TGS DLQMV + LRVLTRP LP +Y+ LG +Y ERVLP
Sbjct: 75 FQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLTRPNAAELPSMYQRLGLDYEERVLP 134
Query: 498 SIIHETLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFT 677
SI++E LK+VVA++NASQLITQR VS IR+ LTERA +F + LDDV+IT L+F +E+T
Sbjct: 135 SIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYT 194
Query: 678 AAIEANKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
AA+EA K + ++ +A+QE+ G + +A+++G+A++ N
Sbjct: 195 AAVEA-KQVAQQEAQRAQFLVEKAKQEQKQKIVQAEGEATAAKMLGEALSRN 245
>sp|Q9P7H3|PHB1_SCHPO Prohibitin-1 OS=Schizosaccharomyces pombe GN=phb1 PE=2
SV=1
Length = 282
Score = 197 bits (500), Expect = 1e-049
Identities = 98/179 (54%), Positives = 136/179 (75%)
Frame = +3
Query: 153 LSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPI 332
L + + ++ G+G L +S+Y+V GG RAV+F+RL+G++++V EGTHF++PW ++ I
Sbjct: 5 LERVARYAIPIGIGFTLLQSSIYDVPGGKRAVLFDRLSGVQKQVVQEGTHFLIPWLQKAI 64
Query: 333 IYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHE 512
+YDVR RP + +TTGS DLQMV + LRVL RP LP IY+ LG +Y ERVLPSI +E
Sbjct: 65 VYDVRTRPRNIATTTGSKDLQMVSLTLRVLHRPEVGMLPQIYQNLGLDYDERVLPSIGNE 124
Query: 513 TLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIE 689
LK+VVAQ++A++LITQRE VS +IR+ L +RA+ F I L+DVSIT +TFGKEFT A+E
Sbjct: 125 ILKSVVAQFDAAELITQREVVSAKIRQELVQRATEFGIRLEDVSITHMTFGKEFTKAVE 183
>sp|P67778|PHB_MOUSE Prohibitin OS=Mus musculus GN=Phb PE=1 SV=1
Length = 272
Score = 197 bits (499), Expect = 1e-049
Identities = 97/178 (54%), Positives = 134/178 (75%), Gaps = 4/178 (2%)
Frame = +3
Query: 165 LKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDV 344
L ++V GG+ + ++LYNV+ GHRAV+F+R G+++ V EGTHF++PW ++PII+D
Sbjct: 14 LALAVAGGV----VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDC 69
Query: 345 RARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKA 524
R+RP V TGS DLQ V + LR+L RP+ +LP IY ++GE+Y ERVLPSI E LK+
Sbjct: 70 RSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKS 129
Query: 525 VVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEANK 698
VVA+++A +LITQRE VSR++ LTERA+ F + LDDVS+T LTFGKEFT A+EA +
Sbjct: 130 VVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQ 187
>sp|P67779|PHB_RAT Prohibitin OS=Rattus norvegicus GN=Phb PE=1 SV=1
Length = 272
Score = 197 bits (499), Expect = 1e-049
Identities = 97/178 (54%), Positives = 134/178 (75%), Gaps = 4/178 (2%)
Frame = +3
Query: 165 LKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDV 344
L ++V GG+ + ++LYNV+ GHRAV+F+R G+++ V EGTHF++PW ++PII+D
Sbjct: 14 LALAVAGGV----VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDC 69
Query: 345 RARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKA 524
R+RP V TGS DLQ V + LR+L RP+ +LP IY ++GE+Y ERVLPSI E LK+
Sbjct: 70 RSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKS 129
Query: 525 VVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEANK 698
VVA+++A +LITQRE VSR++ LTERA+ F + LDDVS+T LTFGKEFT A+EA +
Sbjct: 130 VVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQ 187
>sp|Q54GI9|PHB1_DICDI Prohibitin-1, mitochondrial OS=Dictyostelium discoideum
GN=phbA PE=3 SV=1
Length = 271
Score = 196 bits (497), Expect = 2e-049
Identities = 106/227 (46%), Positives = 160/227 (70%), Gaps = 3/227 (1%)
Frame = +3
Query: 153 LSALLKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPI 332
L+ L+ +++ G G+ +S+Y V+GG RAV+F+R++G+KEK EGTHF++PW ++PI
Sbjct: 5 LNKLIPLALTVGTGLSLAQSSMYTVDGGQRAVIFDRISGVKEKSVGEGTHFIMPWLQKPI 64
Query: 333 IYDVRARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHE 512
I+D+R+ P ++S TGS DLQ V V +RVL RP + LP I+ LG +Y ER+LPS+ +E
Sbjct: 65 IFDIRSSPRNIKSDTGSKDLQTVSVTVRVLFRPDVEHLPSIFSKLGLDYDERILPSLGNE 124
Query: 513 TLKAVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEA 692
LK+VVAQY+A++LITQRE VS+EIR+ L +RA F++ LDDVSIT L+F ++FT AIE
Sbjct: 125 VLKSVVAQYDATELITQREVVSKEIRESLMKRAKEFNLLLDDVSITHLSFSQDFTNAIE- 183
Query: 693 NKSLLRR*TC*VHCGESRARQEKCSH--PCGGRS*SAQLIGQAIANN 827
+K + ++ + QEK ++ G + +A+LIGQA+ N+
Sbjct: 184 HKQVAQQEAERSKYIVMKNEQEKKANIIRAEGEAEAAKLIGQAMGNS 230
>sp|Q3T165|PHB_BOVIN Prohibitin OS=Bos taurus GN=PHB PE=2 SV=1
Length = 272
Score = 195 bits (495), Expect = 4e-049
Identities = 96/178 (53%), Positives = 134/178 (75%), Gaps = 4/178 (2%)
Frame = +3
Query: 165 LKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDV 344
L ++V GG+ + ++LYNV+ GHRAV+F+R G+++ V EGTHF++PW ++PII+D
Sbjct: 14 LALAVAGGV----VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDC 69
Query: 345 RARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKA 524
R+RP V TGS DLQ V + LR+L RP+ +LP I+ ++GE+Y ERVLPSI E LK+
Sbjct: 70 RSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKS 129
Query: 525 VVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEANK 698
VVA+++A +LITQRE VSR++ LTERA+ F + LDDVS+T LTFGKEFT A+EA +
Sbjct: 130 VVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQ 187
>sp|P35232|PHB_HUMAN Prohibitin OS=Homo sapiens GN=PHB PE=1 SV=1
Length = 272
Score = 195 bits (495), Expect = 4e-049
Identities = 96/178 (53%), Positives = 134/178 (75%), Gaps = 4/178 (2%)
Frame = +3
Query: 165 LKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDV 344
L ++V GG+ + ++LYNV+ GHRAV+F+R G+++ V EGTHF++PW ++PII+D
Sbjct: 14 LALAVAGGV----VNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDC 69
Query: 345 RARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKA 524
R+RP V TGS DLQ V + LR+L RP+ +LP I+ ++GE+Y ERVLPSI E LK+
Sbjct: 70 RSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKS 129
Query: 525 VVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEANK 698
VVA+++A +LITQRE VSR++ LTERA+ F + LDDVS+T LTFGKEFT A+EA +
Sbjct: 130 VVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQ 187
>sp|P84173|PHB_CHICK Prohibitin OS=Gallus gallus GN=PHB PE=1 SV=1
Length = 272
Score = 193 bits (488), Expect = 2e-048
Identities = 94/175 (53%), Positives = 133/175 (76%), Gaps = 4/175 (2%)
Frame = +3
Query: 165 LKVSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDV 344
L ++V GG+ + ++LYNV+ GHRAV+F+R G+++ V EGTHF++PW ++PII+D
Sbjct: 14 LGLAVAGGV----VNSALYNVDAGHRAVIFDRFRGVQDTVVGEGTHFLIPWVQKPIIFDC 69
Query: 345 RARPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKA 524
R+RP + TGS DLQ V + LR+L RP+ +LP I+ ++GE+Y ERVLPSI E LK+
Sbjct: 70 RSRPRNIPVITGSKDLQNVNITLRILFRPVTAQLPRIFTSIGEDYDERVLPSITTEILKS 129
Query: 525 VVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIE 689
VVA+++A +LITQRE VSR++ + LTERA+ F + LDDVS+T LTFGKEFT A+E
Sbjct: 130 VVARFDAGELITQRELVSRQVSEDLTERAATFGLILDDVSLTHLTFGKEFTEAVE 184
>sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex protein 1
OS=Caenorhabditis elegans GN=phb-1 PE=1 SV=1
Length = 275
Score = 190 bits (482), Expect = 1e-047
Identities = 92/173 (53%), Positives = 128/173 (73%), Gaps = 4/173 (2%)
Frame = +3
Query: 171 VSVIGGLGVYALTNSLYNVEGGHRAVMFNRLTGIKEKVYPEGTHFMLPWFERPIIYDVRA 350
+S+ GG+ +LYNV+GG RAV+F+R +G+K +V EGTHF++PW ++PII+D+R+
Sbjct: 19 LSIAGGIA----QTALYNVDGGQRAVIFDRFSGVKNEVVGEGTHFLIPWVQKPIIFDIRS 74
Query: 351 RPYLVESTTGSHDLQMVKVGLRVLTRPMGDRLPHIYRTLGENYSERVLPSIIHETLKAVV 530
P V + TGS DLQ V + LR+L RP DRLP+IY +G +Y+ERVLPSI +E LKAVV
Sbjct: 75 TPRAVTTITGSKDLQNVNITLRILHRPSPDRLPNIYLNIGLDYAERVLPSITNEVLKAVV 134
Query: 531 AQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIE 689
AQ++A ++ITQRE VS+ L ERA+ F + LDD++IT L FG+EFT A+E
Sbjct: 135 AQFDAHEMITQREVVSQRASVALRERAAQFGLLLDDIAITHLNFGREFTEAVE 187
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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