BLASTX 7.6.2
Query= UN21258 /QuerySize=1524
(1523 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|A7MCT6|EKI2_MOUSE Ethanolamine kinase 2 OS=Mus musculus GN=Et... 174 2e-042
sp|Q869T9|EKIA_DICDI Probable ethanolamine kinase A OS=Dictyoste... 166 4e-040
sp|Q9NVF9|EKI2_HUMAN Ethanolamine kinase 2 OS=Homo sapiens GN=ET... 166 6e-040
sp|O54804|CHKA_MOUSE Choline kinase alpha OS=Mus musculus GN=Chk... 159 6e-038
sp|P54352|EAS_DROME Ethanolamine kinase OS=Drosophila melanogast... 143 6e-033
sp|A7SK27|EKI_NEMVE Probable ethanolamine kinase OS=Nematostella... 133 5e-030
sp|Q9HBU6|EKI1_HUMAN Ethanolamine kinase 1 OS=Homo sapiens GN=ET... 112 6e-024
sp|Q9D4V0|EKI1_MOUSE Ethanolamine kinase 1 (Fragment) OS=Mus mus... 112 6e-024
sp|P35790|CHKA_HUMAN Choline kinase alpha OS=Homo sapiens GN=CHK... 111 1e-023
sp|Q01134|CHKA_RAT Choline kinase alpha OS=Rattus norvegicus GN=... 111 1e-023
sp|Q10276|KICH_SCHPO Putative choline kinase OS=Schizosaccharomy... 84 3e-015
sp|Q554D8|EKIB_DICDI Probable ethanolamine kinase B OS=Dictyoste... 80 3e-014
sp|Q9Y259|CHKB_HUMAN Choline/ethanolamine kinase OS=Homo sapiens... 73 4e-012
sp|O55229|CHKB_MOUSE Choline/ethanolamine kinase OS=Mus musculus... 70 3e-011
sp|O54783|CHKB_RAT Choline/ethanolamine kinase OS=Rattus norvegi... 69 8e-011
sp|P46560|KICB3_CAEEL Putative choline kinase B3 OS=Caenorhabdit... 58 1e-007
sp|P46558|KICB1_CAEEL Choline kinase B1 OS=Caenorhabditis elegan... 55 1e-006
>sp|A7MCT6|EKI2_MOUSE Ethanolamine kinase 2 OS=Mus musculus GN=Etnk2 PE=2 SV=1
Length = 385
Score = 174 bits (439), Expect = 2e-042
Identities = 94/279 (33%), Positives = 151/279 (54%), Gaps = 11/279 (3%)
Frame = +1
Query: 481 EDALHRRVLVRIYGDGVDLFFNRDDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTL 660
E+ + VLVR+YG+ +L +R++E++ F+ + HG PKL F +G E++ L
Sbjct: 101 EEDMRDCVLVRVYGERTELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYVQGVAL 160
Query: 661 SAGDLRVTETSDLIAAKLREFHKLDMPG--PKNVLLWERLRTWLKEAKNLCSPT-EIDEF 831
+R + LIA ++ + H + G PK LW ++ + K+ SP+ D
Sbjct: 161 GPEHIREPQLFRLIALEMAKIHTIHANGSLPKPT-LWHKMHRYFTLVKDEISPSLSADVP 219
Query: 832 RLEAMDGEINLLEERLTREDQEIGFCHNDLQYGNVMIDEETNAITIIDYEYSSFNPIAYD 1011
++E ++ E+ L+E L++ D + FCHNDL N++ D + + IDYEY+ +N A+D
Sbjct: 220 KVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGRVCFIDYEYAGYNYQAFD 279
Query: 1012 IANHFCEMAANYHSDTPHVLDYTLYPGEEERRRFISTYL-GSTGNAPSQEEKDRLMTDAE 1188
I NHF E A +V+DY+ YP E + +++ YL G A S E +RL
Sbjct: 280 IGNHFNEFAG------VNVVDYSRYPARETQVQWLRYYLEAQKGTAASPREVERLYAQVN 333
Query: 1189 RYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYW 1305
++ LA+H FW LW +I +TI FD+ YA RF QY+
Sbjct: 334 KFALASHFFWALWALIQNQYSTISFDFLRYAVIRFNQYF 372
>sp|Q869T9|EKIA_DICDI Probable ethanolamine kinase A OS=Dictyostelium discoideum
GN=etnkA PE=3 SV=1
Length = 349
Score = 166 bits (420), Expect = 4e-040
Identities = 93/307 (30%), Positives = 162/307 (52%), Gaps = 14/307 (4%)
Frame = +1
Query: 400 ESLEVVPLKGAMTNEVYQINWPTLNGGEDALHRRVLVRIYGDGVDLFFNRDDEIKTFECM 579
E L + L G +TN +Y + N + + V++R+YG + +R +E+
Sbjct: 42 EDLTIQKLNGGITNVLYLVE--DKNIEQKYRYLPVVIRLYGYKSEEIIDRKNELIIQTEA 99
Query: 580 SHHGYGPKLLGRFSDGRLEEFIHARTLSAGDLRVTETSDLIAAKLREFHKLDMPGPKNVL 759
+G G K G F +G + FI L+ D+ IA ++ ++H ++MP KN
Sbjct: 100 DQNGLGAKFYGLFDNGCIYGFIKGEPLAYEDISKPTMQTCIAKEIAQWHSIEMPTRKNPS 159
Query: 760 LWERLRTWLKEAKNLCSPTEIDEF----RLEAMDGEINLLEERLTREDQEIGFCHNDLQY 927
LW ++ W A ++ E +E+ ++ M E +LE+RL + + I FCHNDL
Sbjct: 160 LWPTIKKWAALAPDVYPVPEKNEYYQSINVKKMIEEGKMLEQRLAQLNSPIVFCHNDLLS 219
Query: 928 GNVMIDEETNAITIIDYEYSSFNPIAYDIANHFCEMAANYHSDTPHVLDYTLYPGEEERR 1107
GN++ D N + ID+EY+++N ++ NHF E A DY+LYP +E +
Sbjct: 220 GNIIYDPSQNCASFIDFEYANYNFRGLELGNHFNEYAG-------FGPDYSLYPNKESQI 272
Query: 1108 RFISTYLGST-GNAPSQEEKDRLMTDAERYTLANHIFWGLWGIISGHVNTIEFDYKEYAR 1284
F++ Y S P+Q+E ++L ++ +++LA+H++WG W I+ + I+FDY EY +
Sbjct: 273 HFLTDYHRSLFKTEPTQDELEKLYIESNQFSLASHLYWGFWAIVQAMNSQIDFDYLEYGK 332
Query: 1285 QRFEQYW 1305
RF++Y+
Sbjct: 333 ARFDRYY 339
>sp|Q9NVF9|EKI2_HUMAN Ethanolamine kinase 2 OS=Homo sapiens GN=ETNK2 PE=2 SV=3
Length = 386
Score = 166 bits (418), Expect = 6e-040
Identities = 91/279 (32%), Positives = 148/279 (53%), Gaps = 11/279 (3%)
Frame = +1
Query: 481 EDALHRRVLVRIYGDGVDLFFNRDDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTL 660
E+ + VLVR+YG+ +L +R++E++ F+ + H PKL F +G E++ L
Sbjct: 102 EEDMQDCVLVRVYGERTELLVDRENEVRNFQLLRAHSCAPKLYCTFQNGLCYEYMQGVAL 161
Query: 661 SAGDLRVTETSDLIAAKLREFHKLDMPG--PKNVLLWERLRTWLKEAKNLCSPT-EIDEF 831
+R LIA ++ + H + G PK + LW ++ + KN +P+ D
Sbjct: 162 EPEHIREPRLFRLIALEMAKIHTIHANGSLPKPI-LWHKMHNYFTLVKNEINPSLSADVP 220
Query: 832 RLEAMDGEINLLEERLTREDQEIGFCHNDLQYGNVMIDEETNAITIIDYEYSSFNPIAYD 1011
++E ++ E+ L+E L++ + + FCHNDL N++ D + IDYEY+ +N A+D
Sbjct: 221 KVEVLERELAWLKEHLSQLESPVVFCHNDLLCKNIIYDSIKGHVRFIDYEYAGYNYQAFD 280
Query: 1012 IANHFCEMAANYHSDTPHVLDYTLYPGEEERRRFISTYL-GSTGNAPSQEEKDRLMTDAE 1188
I NHF E A + +DY LYP E + +++ YL G A + E RL
Sbjct: 281 IGNHFNEFAG------VNEVDYCLYPARETQLQWLHYYLQAQKGMAVTPREVQRLYVQVN 334
Query: 1189 RYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYW 1305
++ LA+H FW LW +I +TI+FD+ YA RF QY+
Sbjct: 335 KFALASHFFWALWALIQNQYSTIDFDFLRYAVIRFNQYF 373
>sp|O54804|CHKA_MOUSE Choline kinase alpha OS=Mus musculus GN=Chka PE=1 SV=2
Length = 453
Score = 159 bits (401), Expect = 6e-038
Identities = 111/359 (30%), Positives = 176/359 (49%), Gaps = 41/359 (11%)
Frame = +1
Query: 364 LGSTWGDVVEDLESLEVVPLKGAMTNEVYQINWPTLNGGEDALHRRVLVRIYG------- 522
L W + ED + V+ +G ++N ++Q + P R+VL+R+YG
Sbjct: 95 LPGAWRGLREDQFHISVI--RGGLSNMLFQCSLPDSIASVGDEPRKVLLRLYGAILKMRS 152
Query: 523 ---DGVDLFFNRDD---------EIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLSA 666
+G + N ++ E F ++ GPKL G F GRLE+FI +R L
Sbjct: 153 CNKEGSEQAQNENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDT 212
Query: 667 GDLRVTETSDLIAAKLREFHKLDMPGPKN-VLLWERLRTWLKEAKNLCSPTEIDEFRLEA 843
+LR+ + S IA K+ FH + MP K L+ + +L + L E +L
Sbjct: 213 EELRLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLNQVLRLKFSREARVQQLHK 272
Query: 844 -----MDGEINLLEERLTREDQEIGFCHNDLQYGNVMI-----DEETNAITIIDYEYSSF 993
+ E+ L L + FCHND Q GN+++ + E + +ID+EYSS+
Sbjct: 273 ILSYNLPLELENLRSLLQYTRSPVVFCHNDCQEGNILLLEGQENSERRKLMLIDFEYSSY 332
Query: 994 NPIAYDIANHFCEMAANY-HSDTPHV-LDYTLYPGEEERRRFISTYLGSTGN---APSQE 1158
N +DI NHFCE +Y + P + YP +++ FIS+YL + N + S E
Sbjct: 333 NYRGFDIGNHFCEWMYDYTYEKYPFFRANIQKYPSRKQQLHFISSYLTTFQNDFESLSSE 392
Query: 1159 E----KDRLMTDAERYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRKQML 1323
E K+ ++ + R+ LA+H WGLW I+ +++IEF Y EYA+ RFE Y+ +K+ L
Sbjct: 393 EQFATKEDMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMEYAQARFEAYFDQKRKL 451
>sp|P54352|EAS_DROME Ethanolamine kinase OS=Drosophila melanogaster GN=eas PE=1
SV=2
Length = 518
Score = 143 bits (358), Expect = 6e-033
Identities = 88/285 (30%), Positives = 139/285 (48%), Gaps = 20/285 (7%)
Frame = +1
Query: 502 VLVRIYGDGVDLFFNRDDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLSAGDLRV 681
VLVRIYG+ DL +R E + F + +G P L F +G + E++ TL+ +
Sbjct: 227 VLVRIYGNKTDLLIDRKAETQNFLLLHTYGLAPSLYATFKNGLVYEYVPGTTLNTDSVLC 286
Query: 682 TETSDLIAAKLREFH-KLDMPGPKNV-----LLWERLRTWLKEAKNLCSPTEIDE----- 828
E L+A ++ E H K+ G + ++W++ +++L S E +
Sbjct: 287 PEIWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLVPERFSDAEKHKRVKET 346
Query: 829 -FRLEAMDGEINLLEERLTREDQEIGFCHNDLQYGNVMIDEETNAITIIDYEYSSFNPIA 1005
+ + E N L E L D I F HNDL GNV+ + N + IDYEY+ +N A
Sbjct: 347 FLPIGRLREEFNKLYEYLEALDSPIVFSHNDLLLGNVIYTQSLNTVNFIDYEYADYNFQA 406
Query: 1006 YDIANHFCEMAANYHSDTPHVLDYTLYPGEEERRRFISTYLGS--TGNAPSQEEKDRLMT 1179
+DI NHF EM +DY+ YP E + +++ YL + +E + L
Sbjct: 407 FDIGNHFAEMCG------VDEVDYSRYPKREFQLQWLRVYLEEYLQRSNIQNDEVELLYV 460
Query: 1180 DAERYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRK 1314
++ LA+HIFW +W ++ +TI+FDY YA R+ +Y RK
Sbjct: 461 QVNQFALASHIFWTVWSLLQAEHSTIDFDYVGYAFLRYNEYLARK 505
>sp|A7SK27|EKI_NEMVE Probable ethanolamine kinase OS=Nematostella vectensis
GN=etnk PE=3 SV=1
Length = 349
Score = 133 bits (333), Expect = 5e-030
Identities = 63/165 (38%), Positives = 100/165 (60%), Gaps = 13/165 (7%)
Frame = +1
Query: 853 EINLLEERLTREDQEIGFCHNDLQYGNVMIDEETNAITIIDYEYSSFNPIAYDIANHFCE 1032
E+ LL+ +L + + I F HNDL N++ +++ +++ ID+EY++ NPIAYDIANHFCE
Sbjct: 186 EVKLLKSKLDKLESAIVFAHNDLLCKNIIYNKDKDSVCTIDFEYANPNPIAYDIANHFCE 245
Query: 1033 MAANYHSDTPHVLDYTLYPGEEERRRFISTYL-------GSTGNAPSQEEKDRLMTDAER 1191
A +DY+LYP ++ + +F+ +YL G PS E ++L +
Sbjct: 246 YAG------VDEVDYSLYPQKDHQVKFLESYLKRAMELQGEKDVNPSSREIEKLYVHVNQ 299
Query: 1192 YTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRKQMLL 1326
+ LA H FWG+WG++ H + I+FD+ EYA R +Y+LRK+ L
Sbjct: 300 FALAAHFFWGVWGLVQAHYSEIDFDFLEYAITRLNEYYLRKEKFL 344
>sp|Q9HBU6|EKI1_HUMAN Ethanolamine kinase 1 OS=Homo sapiens GN=ETNK1 PE=1 SV=1
Length = 452
Score = 112 bits (280), Expect = 6e-024
Identities = 60/165 (36%), Positives = 92/165 (55%), Gaps = 12/165 (7%)
Frame = +1
Query: 838 EAMDGEINLLEERLTREDQEIGFCHNDLQYGNVMIDEETNAITIIDYEYSSFNPIAYDIA 1017
+ + E+ ++E L+ + CHNDL N++ +E+ + IDYEYS +N +AYDI
Sbjct: 284 QILQEEMTWMKEILSNLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIG 343
Query: 1018 NHFCEMAANYHSDTPHVLDYTLYPGEEERRRFISTYLGS------TGNAPSQEEKDRLMT 1179
NHF E A SD +DY+LYP E + +++ YL + G +++E + L
Sbjct: 344 NHFNEFAG--VSD----VDYSLYPDRELQSQWLRAYLEAYKEFKGFGTEVTEKEVEILFI 397
Query: 1180 DAERYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRK 1314
++ LA+H FWGLW +I +TIEFD+ YA RF QY+ K
Sbjct: 398 QVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAIVRFNQYFKMK 442
>sp|Q9D4V0|EKI1_MOUSE Ethanolamine kinase 1 (Fragment) OS=Mus musculus GN=Etnk1
PE=2 SV=1
Length = 412
Score = 112 bits (280), Expect = 6e-024
Identities = 60/165 (36%), Positives = 93/165 (56%), Gaps = 12/165 (7%)
Frame = +1
Query: 838 EAMDGEINLLEERLTREDQEIGFCHNDLQYGNVMIDEETNAITIIDYEYSSFNPIAYDIA 1017
+ + E+ ++E L+ + CHNDL N++ +E+ + IDYEYS +N +AYDI
Sbjct: 244 QLLQEEMTWMKELLSSLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIG 303
Query: 1018 NHFCEMAANYHSDTPHVLDYTLYPGEEERRRFISTYLGS------TGNAPSQEEKDRLMT 1179
NHF E A SD +DY+LYP E + + + +YL + G+ +++E + L
Sbjct: 304 NHFNEFAG--VSD----VDYSLYPDRELQGQCVRSYLEAYKEYKGFGSDVTEKEVETLFI 357
Query: 1180 DAERYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRK 1314
++ LA+H FWGLW +I +TIEFD+ YA RF QY+ K
Sbjct: 358 QVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAVVRFNQYFKMK 402
Score = 55 bits (130), Expect = 2e-006
Identities = 36/108 (33%), Positives = 52/108 (48%), Gaps = 10/108 (9%)
Frame = +1
Query: 484 DALHRRVLVRIYGDGVDLFFNRDDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLS 663
D + VLVRIYG+ +L +RD+E+K+F + HG P+L F++G EFI L
Sbjct: 118 DTMEDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGELLD 177
Query: 664 AGDLRVTETSDLIAAKLREFHKLDMPG---PKNVLLWERLRTWLKEAK 798
+ LIA +L + H + PK+ L WLK K
Sbjct: 178 PQHVCNPAIFRLIARQLAKIHAIHAHNGWIPKSNL-------WLKMGK 218
>sp|P35790|CHKA_HUMAN Choline kinase alpha OS=Homo sapiens GN=CHKA PE=1 SV=3
Length = 457
Score = 111 bits (277), Expect = 1e-023
Identities = 59/171 (34%), Positives = 95/171 (55%), Gaps = 14/171 (8%)
Frame = +1
Query: 853 EINLLEERLTREDQEIGFCHNDLQYGNVMI-----DEETNAITIIDYEYSSFNPIAYDIA 1017
E+ L L + FCHND Q GN+++ + E + +ID+EYSS+N +DI
Sbjct: 285 ELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIG 344
Query: 1018 NHFCEMAANYHSDTPHVLDYTL--YPGEEERRRFISTYLGSTGN---APSQEE----KDR 1170
NHFCE +Y + + YP ++++ FIS+YL + N S EE K+
Sbjct: 345 NHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEE 404
Query: 1171 LMTDAERYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRKQML 1323
++ + R+ LA+H WGLW I+ +++IEF Y +YA+ RF+ Y+ +K+ L
Sbjct: 405 MLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKL 455
>sp|Q01134|CHKA_RAT Choline kinase alpha OS=Rattus norvegicus GN=Chka PE=2 SV=2
Length = 453
Score = 111 bits (277), Expect = 1e-023
Identities = 61/171 (35%), Positives = 96/171 (56%), Gaps = 14/171 (8%)
Frame = +1
Query: 853 EINLLEERLTREDQEIGFCHNDLQYGNVMI-----DEETNAITIIDYEYSSFNPIAYDIA 1017
E+ L L + FCHND Q GN+++ + E + +ID+EYSS+N +DI
Sbjct: 281 ELENLRSLLQYTRSPVVFCHNDCQEGNILLLEGQENSEKQKLMLIDFEYSSYNYRGFDIG 340
Query: 1018 NHFCEMAANY-HSDTPHV-LDYTLYPGEEERRRFISTYLGSTGN---APSQEE----KDR 1170
NHFCE +Y + P + YP +++ FIS+YL + N + S EE K+
Sbjct: 341 NHFCEWMYDYTYEKYPFFRANIQKYPTRKQQLHFISSYLTTFQNDFESLSSEEQSATKED 400
Query: 1171 LMTDAERYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRKQML 1323
++ + R+ LA+H WGLW I+ +++IEF Y EYA+ RF+ Y+ +K+ L
Sbjct: 401 MLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMEYAQARFDAYFDQKRKL 451
>sp|Q10276|KICH_SCHPO Putative choline kinase OS=Schizosaccharomyces pombe
GN=SPAC13G7.12c PE=2 SV=1
Length = 456
Score = 84 bits (205), Expect = 3e-015
Identities = 53/169 (31%), Positives = 86/169 (50%), Gaps = 16/169 (9%)
Frame = +1
Query: 325 CSSPDDLKR-----VLQTLG-STWGDVVEDL-ESLEVVPLKGAMTNEVYQINWPTLNGGE 483
C+ PD + R ++ L S+W + L L + + GA+TN VY + P E
Sbjct: 29 CNDPDPIFRHKVLVIIHKLAISSWNRIPLTLCNKLHIKRISGALTNAVYYVAPP-----E 83
Query: 484 DALHRRVLVRIYGDGVDLFFNRDDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLS 663
++L+RIYG V+LF NR E++ + ++ H GP L+G FS+GR E+++ + TL+
Sbjct: 84 GYHAPKLLLRIYGPHVELFINRQVELENLKRLARHNIGPYLIGEFSNGRFEQYMESTTLT 143
Query: 664 AGDLRVTETSDLIAAKLREFHKLDMPGPKNVL----LWERLRTWLKEAK 798
+R + S + +L E H + P VL W+ WL +AK
Sbjct: 144 CKTIRDPKLSIYVGRRLCELHNFILLHPHEVLEMPAAWKNCLVWLPKAK 192
>sp|Q554D8|EKIB_DICDI Probable ethanolamine kinase B OS=Dictyostelium discoideum
GN=etnkB PE=3 SV=1
Length = 447
Score = 80 bits (197), Expect = 3e-014
Identities = 50/146 (34%), Positives = 80/146 (54%), Gaps = 18/146 (12%)
Frame = +1
Query: 760 LWERLRTWL--------KEAK-NLCSPTEIDEFRLEAMDGEINLLEERLTREDQEIGFCH 912
L++ L +W+ KE+K ++ S ++ ++ EAM ++ +EE + E+ I FCH
Sbjct: 221 LFKNLNSWINNAMTLTSKESKGSMISKINLNRYKEEAM-SLMSFIEEHYSGEEY-INFCH 278
Query: 913 NDLQYGNVMIDEETNAITIIDYEYSSFNPIAYDIANHFCEMAANYHSDTPHVLDYTLYPG 1092
NDL N++ ++E + ID+EYS +N YDI N FCE + LDYT YP
Sbjct: 279 NDLIPRNMIYNKEKGQVKFIDFEYSGYNFRGYDIGNFFCEFSG-------LDLDYTKYPS 331
Query: 1093 EEERRRFISTYLGSTGNAPSQEEKDR 1170
E ++RFI YL S N + ++K +
Sbjct: 332 IEIQKRFIKNYLISINNCKNIQQKQK 357
Score = 60 bits (144), Expect = 4e-008
Identities = 27/60 (45%), Positives = 39/60 (65%)
Frame = +1
Query: 1147 PSQEEKDRLMTDAERYTLANHIFWGLWGIISGHVNTIEFDYKEYARQRFEQYWLRKQMLL 1326
PS+EE L ++ TL +H+ WG WGII ++I+FDY +YA +RF+QY L K +L
Sbjct: 385 PSKEEIHNLYIESNHLTLGSHLMWGFWGIIQHFSSSIDFDYIDYAIKRFKQYDLVKNKVL 444
>sp|Q9Y259|CHKB_HUMAN Choline/ethanolamine kinase OS=Homo sapiens GN=CHKB PE=1
SV=3
Length = 395
Score = 73 bits (178), Expect = 4e-012
Identities = 37/88 (42%), Positives = 53/88 (60%), Gaps = 6/88 (6%)
Frame = +1
Query: 1078 TLYPGEEERRRFISTYLGST--GNAPSQEE----KDRLMTDAERYTLANHIFWGLWGIIS 1239
T YP +E++ FI YL G SQEE ++ L+ + RY LA+H FWGLW I+
Sbjct: 301 TDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQ 360
Query: 1240 GHVNTIEFDYKEYARQRFEQYWLRKQML 1323
++TIEF Y +YA+ RF+ Y+ +K L
Sbjct: 361 ASMSTIEFGYLDYAQSRFQFYFQQKGQL 388
>sp|O55229|CHKB_MOUSE Choline/ethanolamine kinase OS=Mus musculus GN=Chkb PE=1
SV=3
Length = 394
Score = 70 bits (171), Expect = 3e-011
Identities = 36/88 (40%), Positives = 52/88 (59%), Gaps = 6/88 (6%)
Frame = +1
Query: 1078 TLYPGEEERRRFISTYLGST--GNAPSQEE----KDRLMTDAERYTLANHIFWGLWGIIS 1239
T YP E++ FI YL G S+EE ++ L+ + RY+LA+H FWGLW +
Sbjct: 301 TDYPTREQQLHFIRHYLAEVQKGEILSEEEQKKREEELLLEISRYSLASHFFWGLWSTLQ 360
Query: 1240 GHVNTIEFDYKEYARQRFEQYWLRKQML 1323
++TIEF Y EYA+ RF+ Y+ +K L
Sbjct: 361 ASMSTIEFGYLEYAQSRFQFYFQQKGQL 388
>sp|O54783|CHKB_RAT Choline/ethanolamine kinase OS=Rattus norvegicus GN=Chkb
PE=1 SV=3
Length = 394
Score = 69 bits (167), Expect = 8e-011
Identities = 35/86 (40%), Positives = 50/86 (58%), Gaps = 6/86 (6%)
Frame = +1
Query: 1084 YPGEEERRRFISTYLGST--GNAPSQEEKDR----LMTDAERYTLANHIFWGLWGIISGH 1245
YP E++ FI YL G S+EE+ + L+ + RY LA+H FWGLW +
Sbjct: 303 YPTREQQLLFIRHYLAEVQKGEVLSEEEQKKQEEDLLIEISRYALASHFFWGLWSTLQAS 362
Query: 1246 VNTIEFDYKEYARQRFEQYWLRKQML 1323
++TIEF Y EYA+ RF+ Y+ +K L
Sbjct: 363 MSTIEFGYLEYAQSRFQFYFQQKGQL 388
>sp|P46560|KICB3_CAEEL Putative choline kinase B3 OS=Caenorhabditis elegans
GN=ckb-3 PE=2 SV=2
Length = 368
Score = 58 bits (139), Expect = 1e-007
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Frame = +1
Query: 505 LVRIYGDGVDLFFNRDDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLSAGDLRVT 684
++RI+ +G F D +I F S G GPKL G F +GR+EEF+ + TL D+ T
Sbjct: 68 VLRIHREGQSQF---DTDIVNFAIFSERGLGPKLYGFFEEGRMEEFLPSVTLKLNDVLNT 124
Query: 685 ETSDLIAAKLREFHKLDMPGPKNVLLWERLRTWLKEAKNL 804
E S I A ++H +++P K+ ++ +R L + + L
Sbjct: 125 EISRKIGAAFPKYHAINVPVSKSRRCFQIMRESLHDYQAL 164
>sp|P46558|KICB1_CAEEL Choline kinase B1 OS=Caenorhabditis elegans GN=ckb-1 PE=2
SV=2
Length = 371
Score = 55 bits (131), Expect = 1e-006
Identities = 34/100 (34%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Frame = +1
Query: 505 LVRIYGDGVDLFFNRDDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLSAGDLRVT 684
L+RI+ G F + F S G GPKL G F GR+EEF+ +RTL + +
Sbjct: 68 LLRIHRQGPSHVFM---DTVNFAIFSERGLGPKLYGFFDGGRMEEFLPSRTLDSDCILDP 124
Query: 685 ETSDLIAAKLREFHKLDMPGPKNVLLWERLRTWLKEAKNL 804
E S + A ++H +D+P K ++ +R LKE ++L
Sbjct: 125 EISRRVGAVYPKYHAIDVPVSKKRRCFQVMRESLKEYQDL 164
Score = 54 bits (127), Expect = 4e-006
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Frame = +1
Query: 871 ERLTRE--DQEIGFCHNDLQYGNVMIDEETNAITIIDYEYSSFNPIAYDIANHFCEMAAN 1044
E+ T E + + FCHNDL N++ T + +ID+E+ S+N +D+A H E AA+
Sbjct: 198 EKWTNELFEDTVVFCHNDLASSNILELNSTKELVLIDWEFGSYNCRGFDLAMHLAETAAD 257
Query: 1045 YHSDTP 1062
+ TP
Sbjct: 258 FRDSTP 263
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
|
