BLASTX 7.6.2
Query= UN21331 /QuerySize=1208
(1207 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 ... 393 2e-108
sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 ... 341 6e-093
sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 ... 324 1e-087
sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 ... 201 1e-050
sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 ... 199 4e-050
sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 ... 199 4e-050
sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 ... 197 1e-049
sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 ... 196 3e-049
sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 ... 196 4e-049
sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation ... 188 1e-046
sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2... 174 1e-042
sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 ... 172 5e-042
sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 ... 132 4e-030
sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 ... 132 6e-030
>sp|Q41969|IF2B_ARATH Eukaryotic translation initiation factor 2 subunit beta
OS=Arabidopsis thaliana GN=EMB1401 PE=2 SV=3
Length = 268
Score = 393 bits (1007), Expect = 2e-108
Identities = 206/271 (76%), Positives = 228/271 (84%), Gaps = 8/271 (2%)
Frame = +2
Query: 203 NEIKEVKDDQD-LAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAG 379
+EI E++++Q+ LAPFDP+KKKKKKKVVIQ+P+ED ESSQ EKSDSLP NDGLESSF G
Sbjct: 3 DEINEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSFTG 62
Query: 380 LKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDYIY 559
+KKKKKKP E SS LN ES+D EDLDE AND++E EGI L QQRYPWEGS+RDYIY
Sbjct: 63 MKKKKKKPTE-SSLLNNESVDAGEDLDEIANDEQEGEEGIVL---QQRYPWEGSERDYIY 118
Query: 560 DELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVM 739
DELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVM
Sbjct: 119 DELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVM 178
Query: 740 NFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRHLPWL--QSPDTIFSKENC 913
+LLAELGTSGSLDGQQRLVVKGRFAP+ + + R+ ++ L +SPDTI SKEN
Sbjct: 179 QYLLAELGTSGSLDGQQRLVVKGRFAPK-NFEGILRRYITDYVICLGCKSPDTILSKENR 237
Query: 914 FFFFRCEKCGFGRSVAQIKAGFVARVGRRKT 1006
FF RCEKCG RSVA IK GFVARV RRKT
Sbjct: 238 LFFLRCEKCGSQRSVAPIKTGFVARVSRRKT 268
Score = 387 bits (994), Expect = 8e-107
Identities = 205/270 (75%), Positives = 224/270 (82%), Gaps = 9/270 (3%)
Frame = +2
Query: 194 DENNEIKEVKDDQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSF 373
DE NEI+E + + LAPFDP+KKKKKKKVVIQ+P+ED ESSQ EKSDSLP NDGLESSF
Sbjct: 3 DEINEIRE--EQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSF 60
Query: 374 AGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDY 553
G+KKKKKKP E SS LN ES+D EDLDE AND++E EGI L QQRYPWEGS+RDY
Sbjct: 61 TGMKKKKKKPTE-SSLLNNESVDAGEDLDEIANDEQEGEEGIVL---QQRYPWEGSERDY 116
Query: 554 IYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDH 733
IYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDH
Sbjct: 117 IYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDH 176
Query: 734 VMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRHLPWL--QSPDTIFSKE 907
VM +LLAELGTSGSLDGQQRLVVKGRFAP+ + + R+ ++ L +SPDTI SKE
Sbjct: 177 VMQYLLAELGTSGSLDGQQRLVVKGRFAPK-NFEGILRRYITDYVICLGCKSPDTILSKE 235
Query: 908 NCFFFFRCEKCGFGRSVAQIKAGFVARVGR 997
N FF RCEKCG RSVA IK GFVARV R
Sbjct: 236 NRLFFLRCEKCGSQRSVAPIKTGFVARVSR 265
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 subunit beta
OS=Malus domestica PE=2 SV=2
Length = 271
Score = 341 bits (874), Expect = 6e-093
Identities = 190/275 (69%), Positives = 211/275 (76%), Gaps = 14/275 (5%)
Frame = +2
Query: 191 ADENNEIKEVKDD--QDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLE 364
AD+N EVKD+ D+APFDPTKKKKKK+VVIQD +D + EK+++ A++G E
Sbjct: 2 ADDNQ--NEVKDEVVADIAPFDPTKKKKKKEVVIQDTTDD-SVGKLAEKAEACTASEGQE 58
Query: 365 SSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSD 544
S+FAGLKKKKKKP+E +S LNEES D EDL+E +DEE EGI L+ YPWEGSD
Sbjct: 59 STFAGLKKKKKKPIE-TSILNEESGDAVEDLNERTGEDEE-GEGIVLETPS--YPWEGSD 114
Query: 545 RDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQ 724
RDY Y+ELL RVF ILRENNP+LAGDRRRTVMRPPQVLREGTKK VFVNFMDLCKTMHRQ
Sbjct: 115 RDYTYEELLDRVFTILRENNPDLAGDRRRTVMRPPQVLREGTKKAVFVNFMDLCKTMHRQ 174
Query: 725 PDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRHLP---WLQSPDTI 895
PDHVM FLLAELGTSGSLDGQQRLVVKGRFAP+ LR V QSPDTI
Sbjct: 175 PDHVMAFLLAELGTSGSLDGQQRLVVKGRFAPK--NFEGILRRYVNEYVICLGCQSPDTI 232
Query: 896 FSKENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
SKEN FF RCEKCG GRSVA KAGF+ARVGRR
Sbjct: 233 LSKENRLFFLRCEKCGSGRSVAPNKAGFMARVGRR 267
>sp|O24473|IF2B_WHEAT Eukaryotic translation initiation factor 2 subunit beta
OS=Triticum aestivum PE=1 SV=1
Length = 270
Score = 324 bits (829), Expect = 1e-087
Identities = 175/269 (65%), Positives = 205/269 (76%), Gaps = 10/269 (3%)
Frame = +2
Query: 206 EIKEVKDDQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLK 385
+++ ++ ++APFDPTKKKKKKKVVIQDP ++ + + EK++ L + E+SF GLK
Sbjct: 6 QMERKEEATEIAPFDPTKKKKKKKVVIQDPADEVDKLA--EKTEGLSVTESGEASFVGLK 63
Query: 386 KKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDYIYDE 565
KKKKK VE+ SL E D + LD+ +DE+ EGI L Q YPWEG+DRDY YDE
Sbjct: 64 KKKKKLVELDPSLVEAG-DGEDTLDDQVGEDEQ-GEGIVLGGATQ-YPWEGTDRDYKYDE 120
Query: 566 LLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNF 745
LLGRVFNILRENNP+LAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP+HVM F
Sbjct: 121 LLGRVFNILRENNPDLAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPEHVMMF 180
Query: 746 LLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRH---LPWLQSPDTIFSKENCF 916
LLAE+GTSGSLDGQQRLV+KGRFAP+ A LR + +SPDTI SKEN
Sbjct: 181 LLAEMGTSGSLDGQQRLVIKGRFAPK--NFEAILRRYINEYVICHGCKSPDTILSKENRL 238
Query: 917 FFFRCEKCGFGRSVAQIKAGFVARVGRRK 1003
FF RCE+CG RSVA IKAGFVA+VGRRK
Sbjct: 239 FFLRCEQCGSSRSVAPIKAGFVAQVGRRK 267
>sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2
OS=Mus musculus GN=Eif2s2 PE=1 SV=1
Length = 331
Score = 201 bits (510), Expect = 1e-050
Identities = 124/277 (44%), Positives = 169/277 (61%), Gaps = 19/277 (6%)
Frame = +2
Query: 194 DENNEIKEVKDD-QDLAPFDPTKKKKK-KKVVIQDPIEDCTESSQPEKSDSLPA--NDGL 361
+E++ K+ DD DL F+ KKKKK KK+ D E+ + + E PA D L
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEAIKDVKIESDAQEPAEPEDDL 117
Query: 362 ESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGS 541
+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W GS
Sbjct: 118 D-IMLGNKKKKKKNVKFPE--EDEILEKDEALED---EDSKKDDGISFSSQT---AWAGS 168
Query: 542 DRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMH 718
+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +H
Sbjct: 169 ERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLH 228
Query: 719 RQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRH---LPWLQSPD 889
RQP H++ FLLAELGTSGS+DG +LV+KGRF + ++ LR ++ +SPD
Sbjct: 229 RQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIEN--VLRRYIKEYVTCHTCRSPD 286
Query: 890 TIFSKENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
TI K+ +F +CE C SVA IK GF A G+R
Sbjct: 287 TILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 323
>sp|Q5E9D0|IF2B_BOVIN Eukaryotic translation initiation factor 2 subunit 2
OS=Bos taurus GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 199 bits (505), Expect = 4e-050
Identities = 123/276 (44%), Positives = 167/276 (60%), Gaps = 15/276 (5%)
Frame = +2
Query: 194 DENNEIKEVKDD-QDLAPFDPTKKKKK-KKVVIQDPIEDCTESSQPEKSDSLPANDGLE- 364
+E++ K+ DD DL F+ KKKKK KK+ D E+ + + E PA +
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKSKKIFDIDEAEEGIKDLKIESDVQEPAEPEEDL 117
Query: 365 SSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSD 544
G KKKKKK V+ +E L+ E L++ +D + +GI Q W GS+
Sbjct: 118 DIMLGNKKKKKKVVKFPD--EDEVLEKDEALED---EDSKKDDGISFSNQTGP-AWAGSE 171
Query: 545 RDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHR 721
RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +HR
Sbjct: 172 RDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLHR 231
Query: 722 QPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRH---LPWLQSPDT 892
QP H++ FLLAELGTSGS+DG +LV+KGRF + ++ LR ++ +SPDT
Sbjct: 232 QPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIEN--VLRRYIKEYVTCHTCRSPDT 289
Query: 893 IFSKENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
I K+ +F +CE C SVA IK GF A GRR
Sbjct: 290 ILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGRR 325
>sp|P41035|IF2B_RABIT Eukaryotic translation initiation factor 2 subunit 2
OS=Oryctolagus cuniculus GN=EIF2S2 PE=1 SV=1
Length = 333
Score = 199 bits (505), Expect = 4e-050
Identities = 124/277 (44%), Positives = 169/277 (61%), Gaps = 17/277 (6%)
Frame = +2
Query: 194 DENNEIKEVKDD-QDLAPFDPTKKKKK-KKVVIQDPIEDCTESSQPEKSDSLPA--NDGL 361
+E++ K+ DD DL F+ KKKKK KK+ D E+ + + E PA D L
Sbjct: 58 EEDSRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLKIENDVQEPAEPEDDL 117
Query: 362 ESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGS 541
+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W GS
Sbjct: 118 D-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDSKKDDGISFSNQTGP-AWAGS 170
Query: 542 DRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMH 718
+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +H
Sbjct: 171 ERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLLH 230
Query: 719 RQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRH---LPWLQSPD 889
RQP H++ FLLAELGTSGS+DG +LV+KGRF + ++ LR ++ +SPD
Sbjct: 231 RQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIEN--VLRRYIKEYVTCHTCRSPD 288
Query: 890 TIFSKENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
TI K+ +F +CE C SVA IK GF A G+R
Sbjct: 289 TILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|P20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2
OS=Homo sapiens GN=EIF2S2 PE=1 SV=2
Length = 333
Score = 197 bits (500), Expect = 1e-049
Identities = 123/278 (44%), Positives = 166/278 (59%), Gaps = 19/278 (6%)
Frame = +2
Query: 194 DENNEIKEVKDDQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDS-----LPANDG 358
+E+ K+ DD D F KKKKKK I D I++ E + K +S D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFD-IDEAEEGVKDLKIESDVQEPTEPEDD 116
Query: 359 LESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEG 538
L+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W G
Sbjct: 117 LD-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDNKKDDGISFSNQTGP-AWAG 169
Query: 539 SDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTM 715
S+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +
Sbjct: 170 SERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLL 229
Query: 716 HRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRH---LPWLQSP 886
HRQP H++ FLLAELGTSGS+DG +LV+KGRF + ++ LR ++ +SP
Sbjct: 230 HRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIEN--VLRRYIKEYVTCHTCRSP 287
Query: 887 DTIFSKENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
DTI K+ +F +CE C SVA IK GF A G+R
Sbjct: 288 DTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKR 325
>sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 subunit 2
OS=Drosophila melanogaster GN=eIF-2beta PE=1 SV=1
Length = 312
Score = 196 bits (497), Expect = 3e-049
Identities = 123/273 (45%), Positives = 159/273 (58%), Gaps = 34/273 (12%)
Frame = +2
Query: 221 KDDQDLAPFDPTKKKKKKKVVIQDPIE---------DCTESSQPEKSDSLPANDGLESSF 373
+D+ DL F KKKKKKK D IE D S +PE+ + N ++ S
Sbjct: 53 EDNLDLESFG-KKKKKKKKPFNMDEIEAAIPSFGGDDVAASEEPEEEE---INLDMDFSM 108
Query: 374 AGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDRDY 553
A KKK KK L+E D A+D D ED E + W GSDRDY
Sbjct: 109 AKKKKKSKK-----KELDELFADQADD------DKSEDKE----NDEDNSSTWFGSDRDY 153
Query: 554 IYDELLGRVFNILRENNPELAGDRR-RTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPD 730
YDELL RVF I+ + NP++A R+ + VMRPPQVLR GTKKT F NFMD+ KT+HR P
Sbjct: 154 TYDELLKRVFEIILDKNPDMAAGRKPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPK 213
Query: 731 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRH---LPWLQSPDTIFS 901
H+++FLLAELGTSGS+DG Q+L++KGRF P+ ++ LR ++ +SP+TI
Sbjct: 214 HLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIEN--VLRRYIKEYVTCHTCRSPETILQ 271
Query: 902 KENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
K+ FF +CE CG SVA IK+GF A G+R
Sbjct: 272 KDTRLFFLQCESCGSRCSVASIKSGFQAVTGKR 304
>sp|Q5R4T9|IF2B_PONAB Eukaryotic translation initiation factor 2 subunit 2
OS=Pongo abelii GN=EIF2S2 PE=2 SV=1
Length = 333
Score = 196 bits (496), Expect = 4e-049
Identities = 122/278 (43%), Positives = 165/278 (59%), Gaps = 19/278 (6%)
Frame = +2
Query: 194 DENNEIKEVKDDQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDS-----LPANDG 358
+E+ K+ DD D F KKKKKK I D I++ E + K +S D
Sbjct: 58 EEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFD-IDEAEEGVKDLKIESDVQEPTEPEDD 116
Query: 359 LESSFAGLKKKKKKPVEISSSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEG 538
L+ G KKKKKK V+ +E L+ E L++ +D + +GI Q W G
Sbjct: 117 LD-IMLGNKKKKKKNVKFPD--EDEILEKDEALED---EDNKKDDGISFSNQTGP-AWAG 169
Query: 539 SDRDYIYDELLGRVFNILRENNPEL-AGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTM 715
S+RDY Y+ELL RVFNI+RE NP++ AG++R+ VM+PPQV+R GTKKT FVNF D+CK +
Sbjct: 170 SERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTDICKLL 229
Query: 716 HRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRH---LPWLQSP 886
HRQP H++ FLLAELGTSGS+DG +LV+KGRF + ++ LR ++ +SP
Sbjct: 230 HRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIEN--VLRRYIKEYVTCHTCRSP 287
Query: 887 DTIFSKENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
DTI K+ +F +CE C S A IK GF A G+R
Sbjct: 288 DTILQKDTRLYFLQCETCHSRCSAASIKTGFQAVTGKR 325
>sp|P56329|IF2B_SCHPO Probable eukaryotic translation initiation factor 2
subunit beta OS=Schizosaccharomyces pombe GN=tif212 PE=1 SV=2
Length = 321
Score = 188 bits (475), Expect = 1e-046
Identities = 116/274 (42%), Positives = 151/274 (55%), Gaps = 35/274 (12%)
Frame = +2
Query: 206 EIKEVKDDQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPANDGLESSFAGLK 385
E+ E+KD F KKKKK K + +S E+++ + G E F+ +K
Sbjct: 72 EVDELKD-----MFSSMKKKKKSKK---------SSASAEEQTEDITTESG-ELDFSSMK 116
Query: 386 KKKKKPVEISSSLNEESL------DTAEDLDEHANDDEEDAEGIDLQQQQQRYPWEGSDR 547
KKKKK S E+ L D DL + D E E + W SDR
Sbjct: 117 KKKKKKKSADLSAFEKELEASSTGDATSDLSKQTFDSENMGE----------HAWLKSDR 166
Query: 548 DYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP 727
DY Y ELL R F +LR NNPELAG++R+ + PP V REG KKT+F N D+ K MHR
Sbjct: 167 DYYYPELLNRFFTLLRTNNPELAGEKRKYTIVPPSVHREG-KKTIFANISDISKRMHRSL 225
Query: 728 DHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRHL--PWLQSPDTIFS 901
DHV+ FL AELGTSGS+DG RL++KGRF + + R+ V ++ +SPDTI +
Sbjct: 226 DHVIQFLFAELGTSGSVDGSSRLIIKGRFQQK-QIENVLRRYIVEYVTCKTCKSPDTILT 284
Query: 902 KENCFFFFRCEKCGFGRSVAQIKAGFVARVGRRK 1003
KEN FF CE CG RSV IK G+ A++G+RK
Sbjct: 285 KENRIFFMTCEACGSVRSVQAIKTGYQAQIGKRK 318
>sp|A6NK07|IF2BL_HUMAN Eukaryotic translation initiation factor 2 subunit 2-like
protein OS=Homo sapiens PE=1 SV=1
Length = 327
Score = 174 bits (440), Expect = 1e-042
Identities = 92/186 (49%), Positives = 127/186 (68%), Gaps = 7/186 (3%)
Frame = +2
Query: 458 DEHANDDEEDAEGIDLQQQQQRYP-WEGSDRDYIYDELLGRVFNILRENNPEL-AGDRRR 631
++ A +DE++ + + Q P W GS+RDY Y+ELL RVFNI+RE NP++ AG++R+
Sbjct: 136 EDEALEDEDNKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRK 195
Query: 632 TVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGR 811
VM+PPQV+R GTKKT FVNF D+CK +HRQP H++ FLLAELGTSGS+DG +LV+KGR
Sbjct: 196 FVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGR 255
Query: 812 FAPRISKDTAALRH*VRH---LPWLQSPDTIFSKENCFFFFRCEKCGFGRSVAQIKAGFV 982
F + ++ LR ++ +SPDTI K+ +F +CE C SVA IK GF
Sbjct: 256 FQQKQIEN--VLRRYIKEYVTCHTCRSPDTILQKDMRLYFLQCETCHSRCSVAIIKIGFQ 313
Query: 983 ARVGRR 1000
A +G+R
Sbjct: 314 AVMGKR 319
>sp|Q54T27|IF2B_DICDI Eukaryotic translation initiation factor 2 subunit 2
OS=Dictyostelium discoideum GN=eif2s2 PE=3 SV=1
Length = 317
Score = 172 bits (435), Expect = 5e-042
Identities = 100/266 (37%), Positives = 156/266 (58%), Gaps = 15/266 (5%)
Frame = +2
Query: 209 IKEVKDDQDLAPFDPTKKKKKKKVVIQDPIEDCTESSQPEKSDSLPAND-GLESSFAGLK 385
+ + +D+Q+ K+KKKK ++ + +E+ EK ++ A+D +E+ F G K
Sbjct: 44 MSQQEDEQEQEDEKKEKRKKKKAALLASTEGENSEAI--EKLENEGAHDEDIEAEFMGEK 101
Query: 386 KKKKKPVEIS-SSLNEESLDTAEDLDEHANDDEEDAEGIDLQQQ-----QQRYPWEGSDR 547
KKKKK + S ++ + T E + +D E E Q PW G+DR
Sbjct: 102 KKKKKSSKSSTTTTTSTTTTTTEPTETEPTEDGESKEKTITTSDGDTFVQGTIPWAGTDR 161
Query: 548 DYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQP 727
DY Y EL R++++L+ NNP+L D++RT M+PPQV+REGTKKT++ NF ++C T++R+
Sbjct: 162 DYKYSELTYRIYHLLQANNPDLISDQKRT-MKPPQVMREGTKKTIWANFAEICGTLNRKV 220
Query: 728 DHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRHLPW---LQSPDTIF 898
+HV N++ AELGT+GS+DG QRLV++GRF + S+ +RH + +SP+T+
Sbjct: 221 EHVYNYVFAELGTNGSIDGNQRLVIRGRF--KTSQIEIVIRHYISEYVACRNCKSPNTVL 278
Query: 899 SKENCFFFFRCEKCGFGRSVAQIKAG 976
+ N +F C C RSVA IK G
Sbjct: 279 ERNNRLYFLCCNACNSKRSVAVIKKG 304
>sp|Q21230|IF2B_CAEEL Eukaryotic translation initiation factor 2 subunit 2
OS=Caenorhabditis elegans GN=K04G2.1 PE=3 SV=4
Length = 250
Score = 132 bits (332), Expect = 4e-030
Identities = 66/159 (41%), Positives = 103/159 (64%), Gaps = 5/159 (3%)
Frame = +2
Query: 533 EGSDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKT 712
+G+ DY Y+E L V+ ++++ NP+ AGD+++ ++ P+V R G+KKT F NF+++C+
Sbjct: 81 KGAWPDYTYEEALTLVYQVMKDKNPDFAGDKKKFAIKLPEVARAGSKKTAFSNFLEICRL 140
Query: 713 MHRQPDHVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRHLPW---LQS 883
M RQ HV+ FLLAELGT+GS+DG L+VKGR+ + + + LR ++ +S
Sbjct: 141 MKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQK--QFESVLRKYIKEYVMCHTCKS 198
Query: 884 PDTIFSKENCFFFFRCEKCGFGRSVAQIKAGFVARVGRR 1000
P+T +K+ FF +C CG SV IK+GF A VG+R
Sbjct: 199 PETQLTKDTRLFFLQCTNCGSRCSVTAIKSGFKAVVGKR 237
>sp|P09064|IF2B_YEAST Eukaryotic translation initiation factor 2 subunit beta
OS=Saccharomyces cerevisiae GN=SUI3 PE=1 SV=2
Length = 285
Score = 132 bits (331), Expect = 6e-030
Identities = 74/155 (47%), Positives = 100/155 (64%), Gaps = 8/155 (5%)
Frame = +2
Query: 557 YDELLGRVFNILRENNPELAGDRRRTVMR--PPQVLREGTKKTVFVNFMDLCKTMHRQPD 730
Y ELL R FNILR NNPELAGDR R PP LR+G KKT+F N D+ + +HR P+
Sbjct: 131 YSELLSRFFNILRTNNPELAGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPE 189
Query: 731 HVMNFLLAELGTSGSLDGQQRLVVKGRFAPRISKDTAALRH*VRHL--PWLQSPDTIFSK 904
H++ +L AELGTSGS+DGQ+RLV+KG+F + + R+ + ++ +S +T +
Sbjct: 190 HLIQYLFAELGTSGSVDGQKRLVIKGKFQSK-QMENVLRRYILEYVTCKTCKSINTELKR 248
Query: 905 E--NCFFFFRCEKCGFGRSVAQIKAGFVARVGRRK 1003
E N FF C+ CG RSV+ IK GF A VG+R+
Sbjct: 249 EQSNRLFFMVCKSCGSTRSVSSIKTGFQATVGKRR 283
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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