BLASTX 7.6.2
Query= UN21350 /QuerySize=1365
(1364 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q1PSI9|IDND_VITVI L-idonate 5-dehydrogenase OS=Vitis vinifera... 580 9e-165
sp|P27867|DHSO_RAT Sorbitol dehydrogenase OS=Rattus norvegicus G... 327 1e-088
sp|Q64442|DHSO_MOUSE Sorbitol dehydrogenase OS=Mus musculus GN=S... 325 4e-088
sp|Q58D31|DHSO_BOVIN Sorbitol dehydrogenase OS=Bos taurus GN=SOR... 324 2e-087
sp|P07846|DHSO_SHEEP Sorbitol dehydrogenase OS=Ovis aries GN=SOR... 320 1e-086
sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase OS=Homo sapiens GN=S... 319 4e-086
sp|Q4R639|DHSO_MACFA Sorbitol dehydrogenase OS=Macaca fascicular... 318 7e-086
sp|Q5R5F3|DHSO_PONAB Sorbitol dehydrogenase OS=Pongo abelii GN=S... 317 1e-085
sp|Q06004|DHSO_BACSU Sorbitol dehydrogenase OS=Bacillus subtilis... 278 8e-074
sp|A1CFY8|XYL2_ASPCL Probable D-xylulose reductase A OS=Aspergil... 272 4e-072
sp|Q86ZV0|XYL2_ASPOR D-xylulose reductase A OS=Aspergillus oryza... 270 2e-071
sp|Q0CWQ2|XYL2_ASPTN Probable D-xylulose reductase A OS=Aspergil... 268 1e-070
sp|A2QY54|XYL2_ASPNC Probable D-xylulose reductase A OS=Aspergil... 267 1e-070
sp|Q5GN51|XYL2_ASPNG D-xylulose reductase A OS=Aspergillus niger... 267 1e-070
sp|Q02912|DHSO_BOMMO Sorbitol dehydrogenase OS=Bombyx mori GN=SD... 266 3e-070
sp|Q5ARL6|XYL2_EMENI Probable D-xylulose reductase A OS=Emericel... 265 5e-070
sp|C5FTT1|XYL2_NANOT Probable D-xylulose reductase A OS=Nannizzi... 265 5e-070
sp|P35497|DHSO1_YEAST Sorbitol dehydrogenase 1 OS=Saccharomyces ... 265 9e-070
sp|Q07786|DHSO2_YEAST Sorbitol dehydrogenase 2 OS=Saccharomyces ... 262 4e-069
sp|A1D9C9|XYL2_NEOFI Probable D-xylulose reductase A OS=Neosarto... 262 4e-069
>sp|Q1PSI9|IDND_VITVI L-idonate 5-dehydrogenase OS=Vitis vinifera
GN=GSVIVT00012394001 PE=1 SV=2
Length = 366
Score = 580 bits (1494), Expect = 9e-165
Identities = 279/365 (76%), Positives = 323/365 (88%), Gaps = 2/365 (0%)
Frame = -3
Query: 1239 MGKGGMSQG--EGSKVEEENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDV 1066
MGKGG S+ G + EENMAAWL+G+ TLKIQP+ LPSLGP+DV+VR+KAVGICGSDV
Sbjct: 1 MGKGGNSEDAVSGKEHGEENMAAWLLGIKTLKIQPYILPSLGPYDVKVRIKAVGICGSDV 60
Query: 1065 HYLKTMRCADFIVKEPMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEG 886
H+ KTMRCA+FIVK+PMVIGHECAGIIEEVG VK+LV GDRVALEPGISC RC+LC+ G
Sbjct: 61 HHFKTMRCANFIVKKPMVIGHECAGIIEEVGSEVKNLVAGDRVALEPGISCNRCSLCRNG 120
Query: 885 RYNLCPEMKFFATPPVHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAE 706
+YNLC EMKFF +PP +GSLANQVVHP++LCFKLP+NVSLEEGAMCEPLSVG+HACRRA
Sbjct: 121 QYNLCREMKFFGSPPTNGSLANQVVHPSNLCFKLPDNVSLEEGAMCEPLSVGIHACRRAN 180
Query: 705 VGPETNVLVMGAGPIGLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLE 526
VGPETNVL+MG+GPIGLVTMLAARAFG PRIV+VDVDD RL++AK LGAD I++V+T+++
Sbjct: 181 VGPETNVLIMGSGPIGLVTMLAARAFGAPRIVLVDVDDQRLAIAKDLGADDIIRVSTNIQ 240
Query: 525 DVGFEVEQIKKAIGSNVDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPA 346
D+ EV +I+ + + VDV+FDC GFNKTMSTAL ATR GGKVCLVG+ MTVPLTPA
Sbjct: 241 DLDEEVAKIQSTMVTGVDVSFDCVGFNKTMSTALNATRAGGKVCLVGLAQSEMTVPLTPA 300
Query: 345 AAREVDVVGVFRYKNTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAI 166
AAREVD+VG+FRY+NTWPLCLEFL SGKIDVKPLITHRF F QK+VE+AFETSARG NAI
Sbjct: 301 AAREVDIVGIFRYRNTWPLCLEFLRSGKIDVKPLITHRFTFSQKDVEEAFETSARGGNAI 360
Query: 165 KVMFN 151
KVMFN
Sbjct: 361 KVMFN 365
>sp|P27867|DHSO_RAT Sorbitol dehydrogenase OS=Rattus norvegicus GN=Sord PE=1
SV=4
Length = 357
Score = 327 bits (838), Expect = 1e-088
Identities = 167/346 (48%), Positives = 235/346 (67%), Gaps = 7/346 (2%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPMV 1012
EN++ + G ++++ +P+P LGP+DV ++M +VGICGSDVHY + R DF+VK+PMV
Sbjct: 8 ENLSLVVHGPGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMV 67
Query: 1011 IGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVHG 832
+GHE AG + +VG VKHL GDRVA+EPG+ CK GRYNL P + F ATPP G
Sbjct: 68 LGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRYNLTPSIFFCATPPDDG 127
Query: 831 SLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLV 652
+L H AD C+KLP++V+ EEGA+ EPLSVG++ACRR V VLV GAGPIG+V
Sbjct: 128 NLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPIGIV 187
Query: 651 TMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSL-EDVGFEVEQIKKAIGSNV 475
T+L A+A G ++V++D+ +RL+ AK++GAD ++V D+ +VE + +GS
Sbjct: 188 TLLVAKAMGASQVVVIDLSASRLAKAKEVGADFTIQVAKETPHDIAKKVESV---LGSKP 244
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKNTW 295
+VT +C G ++ T + AT GG + +VGMG ++ +PL AA REVD+ GVFRY NTW
Sbjct: 245 EVTIECTGAESSVQTGIYATHSGGTLVVVGMGPEMINLPLVHAAVREVDIKGVFRYCNTW 304
Query: 294 PLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
P+ + L S ++VKPL+THRF +K VE AFET+ +G +KVM
Sbjct: 305 PMAVSMLASKTLNVKPLVTHRFP-LEKAVE-AFETAKKGL-GLKVM 347
>sp|Q64442|DHSO_MOUSE Sorbitol dehydrogenase OS=Mus musculus GN=Sord PE=1 SV=3
Length = 357
Score = 325 bits (833), Expect = 4e-088
Identities = 166/346 (47%), Positives = 237/346 (68%), Gaps = 7/346 (2%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPMV 1012
EN++ + G ++++ +P+P LGP+DV ++M +VGICGSDVHY + R DF+VK+PMV
Sbjct: 8 ENLSLVVHGPGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMV 67
Query: 1011 IGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVHG 832
+GHE AG + +VGE VKHL GDRVA+EPG+ CK GRYNL P + F ATPP G
Sbjct: 68 LGHEAAGTVTKVGELVKHLKPGDRVAIEPGVPREVDEYCKIGRYNLTPTIFFCATPPDDG 127
Query: 831 SLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLV 652
+L H AD C+KLP++V+ EEGA+ EPLSVG++ACRR V VLV GAGP+G+V
Sbjct: 128 NLCRFYKHNADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPVGMV 187
Query: 651 TMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKV-TTSLEDVGFEVEQIKKAIGSNV 475
T+L A+A G ++V+ D+ +RL+ AK++GAD ++V + +++ +VE + +GS
Sbjct: 188 TLLVAKAMGAAQVVVTDLSASRLTKAKEVGADFTIQVGKETPQEIASKVESL---LGSKP 244
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKNTW 295
+VT +C G ++ T + AT GG + +VGMG ++ +PL AA REVD+ GVFRY NTW
Sbjct: 245 EVTIECTGAESSVQTGIYATHSGGTLVIVGMGAEMVNLPLVHAAIREVDIKGVFRYCNTW 304
Query: 294 PLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
P+ + L S ++VKPL+THRF +K VE AFET+ +G +KVM
Sbjct: 305 PMAISMLASKTLNVKPLVTHRFP-LEKAVE-AFETAKKGV-GLKVM 347
>sp|Q58D31|DHSO_BOVIN Sorbitol dehydrogenase OS=Bos taurus GN=SORD PE=2 SV=3
Length = 356
Score = 324 bits (828), Expect = 2e-087
Identities = 166/346 (47%), Positives = 236/346 (68%), Gaps = 7/346 (2%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPMV 1012
EN++ + G L+++ +P+P GP++V ++M +VGICGSDVHY + R DF+VK+PMV
Sbjct: 7 ENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMV 66
Query: 1011 IGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVHG 832
+GHE +G + +VG V+HL GDRVA+EPG CK GRYNL P + F ATPP G
Sbjct: 67 LGHEASGTVVKVGSLVRHLQPGDRVAIEPGAPRETDEFCKIGRYNLSPTIFFCATPPDDG 126
Query: 831 SLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLV 652
+L H A+ C+KLP+NV+ EEGA+ EPLSVG+HACRRA V VLV GAGPIGLV
Sbjct: 127 NLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLV 186
Query: 651 TMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTT-SLEDVGFEVEQIKKAIGSNV 475
++LAA+A G ++V+ D+ +RLS AK++GAD I++++ S +++ +VE + +GS
Sbjct: 187 SLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILQISNESPQEIAKKVEGL---LGSKP 243
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKNTW 295
+VT +C G ++ + AT GG + LVG+G + +VPL AA REVD+ GVFRY NTW
Sbjct: 244 EVTIECTGVETSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTW 303
Query: 294 PLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
P+ + L S ++VKPL+THRF ++ +AFETS +G +KVM
Sbjct: 304 PMAISMLASKSVNVKPLVTHRFPL--EKALEAFETSKKGL-GLKVM 346
>sp|P07846|DHSO_SHEEP Sorbitol dehydrogenase OS=Ovis aries GN=SORD PE=1 SV=1
Length = 354
Score = 320 bits (820), Expect = 1e-086
Identities = 167/350 (47%), Positives = 236/350 (67%), Gaps = 8/350 (2%)
Frame = -3
Query: 1203 KVEEENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVK 1024
K EN++ + G L+++ +P+P GP++V ++M +VGICGSDVHY + R DF+VK
Sbjct: 2 KPAAENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQG-RIGDFVVK 60
Query: 1023 EPMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATP 844
+PMV+GHE +G + +VG V+HL GDRVA++PG CK GRYNL P + F ATP
Sbjct: 61 KPMVLGHEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATP 120
Query: 843 PVHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGP 664
P G+L H A+ C+KLP+NV+ EEGA+ EPLSVG+HACRRA V VLV GAGP
Sbjct: 121 PDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGP 180
Query: 663 IGLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTT-SLEDVGFEVEQIKKAI 487
IGLV +LAA+A G ++V+ D+ +RLS AK++GAD I++++ S E++ +VE + +
Sbjct: 181 IGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGL---L 237
Query: 486 GSNVDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY 307
GS +VT +C G ++ + AT GG + LVG+G + +VPL AA REVD+ GVFRY
Sbjct: 238 GSKPEVTIECTGVETSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRY 297
Query: 306 KNTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
NTWP+ + L S ++VKPL+THRF ++ +AFETS +G +KVM
Sbjct: 298 CNTWPMAISMLASKSVNVKPLVTHRFPL--EKALEAFETSKKGL-GLKVM 344
>sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase OS=Homo sapiens GN=SORD PE=1 SV=4
Length = 357
Score = 319 bits (816), Expect = 4e-086
Identities = 163/344 (47%), Positives = 227/344 (65%), Gaps = 5/344 (1%)
Frame = -3
Query: 1188 NMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPMVI 1009
N++ + G L+++ +P+P GP++V +RM +VGICGSDVHY + R +FIVK+PMV+
Sbjct: 9 NLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVL 68
Query: 1008 GHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVHGS 829
GHE +G +E+VG VKHL GDRVA+EPG CK GRYNL P + F ATPP G+
Sbjct: 69 GHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN 128
Query: 828 LANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLVT 649
L H A C+KLP+NV+ EEGA+ EPLSVG+HACRR V VLV GAGPIG+VT
Sbjct: 129 LCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVT 188
Query: 648 MLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGSNVDV 469
+L A+A G ++V+ D+ RLS AK++GAD ++++ S E +++ +G +V
Sbjct: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQI--SKESPQEIARKVEGQLGCKPEV 246
Query: 468 TFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKNTWPL 289
T +C G ++ + ATR GG + LVG+G + TVPL AA REVD+ GVFRY NTWP+
Sbjct: 247 TIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPV 306
Query: 288 CLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
+ L S ++VKPL+THRF ++ +AFET +G +K+M
Sbjct: 307 AISMLASKSVNVKPLVTHRFPL--EKALEAFETFKKGL-GLKIM 347
>sp|Q4R639|DHSO_MACFA Sorbitol dehydrogenase OS=Macaca fascicularis GN=SORD PE=2
SV=3
Length = 357
Score = 318 bits (814), Expect = 7e-086
Identities = 161/346 (46%), Positives = 233/346 (67%), Gaps = 7/346 (2%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPMV 1012
+N++ + G L+++ +P+P GP++V +RM +VGICGSDVHY + R +FIVK+PMV
Sbjct: 8 KNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEEGRIGNFIVKKPMV 67
Query: 1011 IGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVHG 832
+GHE +G +E+VG VKHL GDRVA+EPG+ CK GRYNL P + F ATPP G
Sbjct: 68 LGHEASGTVEKVGSLVKHLKPGDRVAIEPGVPRENDEFCKSGRYNLSPSIFFCATPPDDG 127
Query: 831 SLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLV 652
+L H A C+KLP+NV+ EEGA+ EPLSVG+HACRR V VLV GAGPIG+V
Sbjct: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHRVLVCGAGPIGVV 187
Query: 651 TMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVT-TSLEDVGFEVEQIKKAIGSNV 475
++L A+A G ++V+ D+ RLS AK++GAD +++++ S +++ +VE + +G
Sbjct: 188 SLLVAKAMGAAQVVVTDLSAPRLSKAKEIGADLVLQISKESPQEIAGKVEGL---LGCKP 244
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKNTW 295
+VT +C G ++ + ATR GG + LVG+G + T+PL AA REVD+ GVFRY NTW
Sbjct: 245 EVTIECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTIPLLHAAVREVDIKGVFRYCNTW 304
Query: 294 PLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
P+ + L S +++KPL+THRF ++ +AFET +G +K+M
Sbjct: 305 PVAISMLASKSVNIKPLVTHRFPL--EKALEAFETFKKGL-GLKIM 347
>sp|Q5R5F3|DHSO_PONAB Sorbitol dehydrogenase OS=Pongo abelii GN=SORD PE=2 SV=1
Length = 357
Score = 317 bits (812), Expect = 1e-085
Identities = 164/345 (47%), Positives = 230/345 (66%), Gaps = 7/345 (2%)
Frame = -3
Query: 1188 NMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPMVI 1009
N++ + G L+++ +P+P GP++V +RM +VGICGSDVHY + R +FIVK+PMV+
Sbjct: 9 NLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEDGRIGNFIVKKPMVL 68
Query: 1008 GHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVHGS 829
GHE +G +E+VG VKHL GDRVA+EPG CK GRYNL P + F ATPP G+
Sbjct: 69 GHEASGTVEKVGSLVKHLKPGDRVAIEPGAPRENDEFCKIGRYNLSPSIFFCATPPDDGN 128
Query: 828 LANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLVT 649
L H A C+KLP+NV+ EEGAM EPLSVG+HACRR V VLV GAGPIG+VT
Sbjct: 129 LCRFYKHNAAFCYKLPDNVTFEEGAMIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVT 188
Query: 648 MLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVT-TSLEDVGFEVEQIKKAIGSNVD 472
+L A+A G ++V+ D+ RLS AK++GAD +++++ S +++ +VE + +G +
Sbjct: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGL---LGCKPE 245
Query: 471 VTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKNTWP 292
VT +C G ++ + AT GG + LVG+G + T+PL AA REVD+ GVFRY NTWP
Sbjct: 246 VTIECTGAGASIQAGIYATHSGGTLVLVGLGSEMTTIPLLHAAIREVDIKGVFRYCNTWP 305
Query: 291 LCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
+ + L S ++VKPLITHRF ++ +AFET +G +K+M
Sbjct: 306 VAISMLASKSVNVKPLITHRFPL--EKALEAFETFKKGL-GLKIM 347
>sp|Q06004|DHSO_BACSU Sorbitol dehydrogenase OS=Bacillus subtilis GN=gutB PE=1
SV=3
Length = 353
Score = 278 bits (710), Expect = 8e-074
Identities = 140/350 (40%), Positives = 218/350 (62%), Gaps = 8/350 (2%)
Frame = -3
Query: 1200 VEEENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKE 1021
V + AA + +KI+ P+P + +V +++ AVGICGSD+HY R +++V++
Sbjct: 5 VPQNMKAAVMHNTREIKIETLPVPDINHDEVLIKVMAVGICGSDLHYYTNGRIGNYVVEK 64
Query: 1020 PMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPP 841
P ++GHECAG I VG V VGDRVA+EPG++C RC CKEGRYNLCP+++F ATPP
Sbjct: 65 PFILGHECAGEIAAVGSSVDQFKVGDRVAVEPGVTCGRCEACKEGRYNLCPDVQFLATPP 124
Query: 840 VHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPI 661
V G+ + D F +P+++S EE A+ EP SVG+HA R ++ P + + +MG GP+
Sbjct: 125 VDGAFVQYIKMRQDFVFLIPDSLSYEEAALIEPFSVGIHAAARTKLQPGSTIAIMGMGPV 184
Query: 660 GLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGS 481
GL+ + AA+AFG I++ D++ RL AK++GA I+ + +D E++ I G
Sbjct: 185 GLMAVAAAKAFGAGTIIVTDLEPLRLEAAKKMGATHIINIRE--QDALEEIKTITNDRG- 241
Query: 480 NVDVTFDCAGFNKTMSTALAATRCGGKVCLVGM-GHGIMTVPLTPAAAREVDVVGVFRYK 304
VDV ++ AG + +ALA+ R GGK+ +VG+ + + + A E+D+ G+FRY
Sbjct: 242 -VDVAWETAGNPAALQSALASVRRGGKLAIVGLPSQNEIPLNVPFIADNEIDIYGIFRYA 300
Query: 303 NTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSN-AIKVM 157
NT+P +EFL SG +D K L+T ++ ++ +DA E + + N +KVM
Sbjct: 301 NTYPKGIEFLASGIVDTKHLVTDQYSL--EQTQDAMERALQFKNECLKVM 348
>sp|A1CFY8|XYL2_ASPCL Probable D-xylulose reductase A OS=Aspergillus clavatus
GN=xdhA PE=3 SV=2
Length = 358
Score = 272 bits (695), Expect = 4e-072
Identities = 143/345 (41%), Positives = 201/345 (58%), Gaps = 4/345 (1%)
Frame = -3
Query: 1206 SKVEEENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFI 1030
S +N++ L G++ +K + P+P L PHDV V +K GICGSDVHY + F+
Sbjct: 4 SSTTPQNLSFVLEGIHQVKFEDRPIPELRDPHDVIVNVKYTGICGSDVHYWEHGAIGHFV 63
Query: 1029 VKEPMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFA 850
VK+PMV+GHE +G++ +VG V L VGDRVA+EPG+ C RC CK G+YNLC +M F A
Sbjct: 64 VKDPMVLGHESSGVVAKVGSAVTSLKVGDRVAMEPGVPCRRCEPCKAGKYNLCEKMAFAA 123
Query: 849 TPPVHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGA 670
TPP G+LA P D C+KLPEN+SL+EGA+ EPL V VH R+A + P +V+V GA
Sbjct: 124 TPPYDGTLAKYYPLPEDFCYKLPENISLQEGALMEPLGVAVHITRQASIKPGESVVVFGA 183
Query: 669 GPIGLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKA 490
GP+GL+ ARAFG +I+ VD+ RL AK+ A I + + + +
Sbjct: 184 GPVGLLCCAVARAFGASKIIAVDIQKTRLDFAKKYAATAIFEPAKVSAVANADQMREEND 243
Query: 489 IGSNVDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFR 310
+G DV D +G ++ T + R GG GMG + P+ A +E+ + G FR
Sbjct: 244 LGPGADVVIDASGAEPSVHTGIHVLRPGGTYVQGGMGRNEINFPIMAACTKELTIKGSFR 303
Query: 309 Y-KNTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARG 178
Y + L ++ + SGK++VK LIT F +E E AF+ G
Sbjct: 304 YGSGDYKLAVDLVASGKVNVKDLITGVVEF--QEAEQAFKEVKAG 346
>sp|Q86ZV0|XYL2_ASPOR D-xylulose reductase A OS=Aspergillus oryzae GN=xdhA PE=3
SV=2
Length = 358
Score = 270 bits (690), Expect = 2e-071
Identities = 145/342 (42%), Positives = 205/342 (59%), Gaps = 8/342 (2%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPM 1015
+N++ L G++ +K + P+P L HDV V ++ GICGSDVHY + F+VK+PM
Sbjct: 9 QNLSFVLEGIHKVKFEDRPIPQLRDAHDVLVDVRFTGICGSDVHYWEHGSIGQFVVKDPM 68
Query: 1014 VIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVH 835
V+GHE +G+I +VG V L VGD VA+EPGI C RC CKEG+YNLC +M F ATPP
Sbjct: 69 VLGHESSGVISKVGSAVTTLKVGDHVAMEPGIPCRRCEPCKEGKYNLCEKMAFAATPPYD 128
Query: 834 GSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGL 655
G+LA V P D C+KLPEN++L+E A+ EPLSV VH ++A V P +V+V GAGP+GL
Sbjct: 129 GTLAKYYVLPEDFCYKLPENINLQEAAVMEPLSVAVHIVKQANVAPGQSVVVFGAGPVGL 188
Query: 654 VTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVT--TSLEDVGFEVEQIKKAIGS 481
+ ARAFG P+++ VD+ RL AK+ A I + + ++LE+ V + +G
Sbjct: 189 LCCAVARAFGSPKVIAVDIQKGRLEFAKKYAATAIFEPSKVSALENAERIVNE--NDLGR 246
Query: 480 NVDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY-K 304
D+ D +G ++ T + R GG GMG +T P+ A +E++V G FRY
Sbjct: 247 GADIVIDASGAEPSVHTGIHVLRPGGTYVQGGMGRNEITFPIMAACTKELNVRGSFRYGS 306
Query: 303 NTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARG 178
+ L + + SGK+ VK LIT F ++ E AF G
Sbjct: 307 GDYKLAVNLVASGKVSVKELITGVVSF--EDAEQAFHEVKAG 346
>sp|Q0CWQ2|XYL2_ASPTN Probable D-xylulose reductase A OS=Aspergillus terreus
(strain NIH 2624 / FGSC A1156) GN=xdhA PE=3 SV=1
Length = 353
Score = 268 bits (683), Expect = 1e-070
Identities = 146/349 (41%), Positives = 200/349 (57%), Gaps = 5/349 (1%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPM 1015
+N++ L G++ +K + P+P L PH V V ++ GICGSDVHY + F+VK+PM
Sbjct: 4 QNLSFVLQGIHQVKFEDRPIPELKDPHGVIVNVRFTGICGSDVHYWEHGSIGQFVVKDPM 63
Query: 1014 VIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVH 835
V+GHE +G+I +VG V L VGDRVA+EPGI C RC CK G+YNLC EM F ATPP
Sbjct: 64 VLGHESSGVITKVGSAVTTLKVGDRVAMEPGIPCRRCEPCKAGKYNLCYEMAFAATPPYD 123
Query: 834 GSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGL 655
G+LA P D C+KLPE ++L+EGA+ EPL V VH R+A V P +V+V GAGP+GL
Sbjct: 124 GTLAKYYALPEDFCYKLPEQITLQEGALMEPLGVAVHIVRQAAVTPGQSVVVFGAGPVGL 183
Query: 654 VTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGSNV 475
+ ARAFG +IV VD+ RL AK A I + + +G
Sbjct: 184 LCCAVARAFGASKIVAVDIQKPRLEFAKNYAATAIFEPAKVAAQENAARLIAENDLGPGA 243
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY-KNT 298
DV D +G ++ T + R GG GMG M P+ A +E++V G FRY
Sbjct: 244 DVAIDASGAEPSVHTGIHVLRTGGTYVQGGMGRSEMNFPIMAACTKELNVKGSFRYGSGD 303
Query: 297 WPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVMFN 151
+ L +E + SG+++VK LIT F +E E AF+ + IK + +
Sbjct: 304 YKLAVELVASGRVNVKELITGVVKF--EEAEQAFK-EVKAGKGIKTLIS 349
>sp|A2QY54|XYL2_ASPNC Probable D-xylulose reductase A OS=Aspergillus niger
(strain CBS 513.88 / FGSC A1513) GN=xdhA PE=3 SV=1
Length = 358
Score = 267 bits (682), Expect = 1e-070
Identities = 140/347 (40%), Positives = 206/347 (59%), Gaps = 5/347 (1%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPM 1015
+N++ L G++ +K + P+P + PHDV V ++ GICGSDVHY + FIVK+PM
Sbjct: 9 QNLSFVLEGIHRVKFEDRPIPEINNPHDVLVNVRFTGICGSDVHYWEHGSIGQFIVKDPM 68
Query: 1014 VIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVH 835
V+GHE +G++ +VG V L VGD VA+EPGI C RC CK G+YNLC +M F ATPP
Sbjct: 69 VLGHESSGVVSKVGSAVTSLKVGDCVAMEPGIPCRRCEPCKAGKYNLCVKMAFAATPPYD 128
Query: 834 GSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGL 655
G+LA V P D C+KLPE+++L+EGA+ EPLSV VH ++A + P +V+V GAGP+GL
Sbjct: 129 GTLAKYYVLPEDFCYKLPESITLQEGAIMEPLSVAVHIVKQAGINPGQSVVVFGAGPVGL 188
Query: 654 VTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGSNV 475
+ A+A+G +++ VD+ RL AK+ A + + + + +GS
Sbjct: 189 LCCAVAKAYGASKVIAVDIQKGRLDFAKKYAATATFEPAKAAALENAQRIITENDLGSGA 248
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY-KNT 298
DV D +G ++ T + R GG GMG +T P+ A +E++V G FRY
Sbjct: 249 DVAIDASGAEPSVHTGIHVLRAGGTYVQGGMGRSEITFPIMAACTKELNVKGSFRYGSGD 308
Query: 297 WPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
+ L + +++GK++VK LIT F ++ E AFE R IK +
Sbjct: 309 YKLAVSLVSAGKVNVKELITGVVKF--EDAERAFE-EVRAGKGIKTL 352
>sp|Q5GN51|XYL2_ASPNG D-xylulose reductase A OS=Aspergillus niger GN=xdhA PE=3
SV=1
Length = 358
Score = 267 bits (682), Expect = 1e-070
Identities = 140/347 (40%), Positives = 206/347 (59%), Gaps = 5/347 (1%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPM 1015
+N++ L G++ +K + P+P + PHDV V ++ GICGSDVHY + FIVK+PM
Sbjct: 9 QNLSFVLEGIHRVKFEDRPIPEINNPHDVLVNVRFTGICGSDVHYWEHGSIGQFIVKDPM 68
Query: 1014 VIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVH 835
V+GHE +G++ +VG V L VGD VA+EPGI C RC CK G+YNLC +M F ATPP
Sbjct: 69 VLGHESSGVVSKVGSAVTSLKVGDCVAMEPGIPCRRCEPCKAGKYNLCVKMAFAATPPYD 128
Query: 834 GSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGL 655
G+LA V P D C+KLPE+++L+EGA+ EPLSV VH ++A + P +V+V GAGP+GL
Sbjct: 129 GTLAKYYVLPEDFCYKLPESITLQEGAIMEPLSVAVHIVKQAGINPGQSVVVFGAGPVGL 188
Query: 654 VTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGSNV 475
+ A+A+G +++ VD+ RL AK+ A + + + + +GS
Sbjct: 189 LCCAVAKAYGASKVIAVDIQKGRLDFAKKYAATATFEPAKAAALENAQRIITENDLGSGA 248
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY-KNT 298
DV D +G ++ T + R GG GMG +T P+ A +E++V G FRY
Sbjct: 249 DVAIDASGAEPSVHTGIHVLRAGGTYVQGGMGRSEITFPIMAACTKELNVKGSFRYGSGD 308
Query: 297 WPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
+ L + +++GK++VK LIT F ++ E AFE R IK +
Sbjct: 309 YKLAVSLVSAGKVNVKELITGVVKF--EDAERAFE-EVRAGKGIKTL 352
>sp|Q02912|DHSO_BOMMO Sorbitol dehydrogenase OS=Bombyx mori GN=SDH PE=2 SV=1
Length = 348
Score = 266 bits (679), Expect = 3e-070
Identities = 137/345 (39%), Positives = 210/345 (60%), Gaps = 4/345 (1%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSLGPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPMV 1012
EN AA L G N ++I+ P+P + +V +++ VGICGSDV T C ++ +P+V
Sbjct: 3 ENYAAVLHGANDVRIEKIPVPEINDDEVLIKIDCVGICGSDVKLYSTGTCGADVIDKPIV 62
Query: 1011 IGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVHG 832
IGHE AG + +VG+ V L VGDRVA+EP C C LCK G+YNLC E ++ ++ G
Sbjct: 63 IGHEGAGTVVKVGDKVSSLRVGDRVAIEPTQPCRSCELCKRGKYNLCVEPRYCSSMGAPG 122
Query: 831 SLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLV 652
+L H AD C KLP+N+++EEGA +PL++ +HAC RA++ + ++++GAGPIG++
Sbjct: 123 NLCRYYKHVADFCHKLPDNLTMEEGAAVQPLAIVIHACNRAKITLGSKIVILGAGPIGIL 182
Query: 651 TMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGSNVD 472
++A+A G +I++ DV +RL A +LGAD ++ V D VE+I K +G D
Sbjct: 183 CAMSAKAMGASKIILTDVVQSRLDAALELGADNVLLVRREYTDEEV-VEKIVKLLGDRPD 241
Query: 471 VTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKNTWP 292
V+ D G+ AL T+ G V +VG+ + +PL+ A REVDVVG FR NT+
Sbjct: 242 VSIDACGYGSAQRVALLVTKTAGLVLVVGIADKTVELPLSQALLREVDVVGSFRIMNTYQ 301
Query: 291 LCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARGSNAIKVM 157
L ++SG I + ITHRF + ++A + + G+ A+K++
Sbjct: 302 PALAAVSSGAIPLDKFITHRFPL--NKTKEALDLAKSGA-AMKIL 343
>sp|Q5ARL6|XYL2_EMENI Probable D-xylulose reductase A OS=Emericella nidulans
GN=xdhA PE=3 SV=1
Length = 359
Score = 265 bits (677), Expect = 5e-070
Identities = 142/340 (41%), Positives = 196/340 (57%), Gaps = 4/340 (1%)
Frame = -3
Query: 1191 ENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKEPM 1015
+N++ L G++ +K + P+P L PHDV V +K GICGSDVHY F+VKEPM
Sbjct: 9 QNLSFVLEGIHRVKFEDRPIPKLKSPHDVIVNVKYTGICGSDVHYWDHGAIGQFVVKEPM 68
Query: 1014 VIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPPVH 835
V+GHE +GI+ ++G V L VGD VA+EPGI C RC CK G+YNLC +M F ATPP
Sbjct: 69 VLGHESSGIVTQIGSAVTSLKVGDHVAMEPGIPCRRCEPCKAGKYNLCEKMAFAATPPYD 128
Query: 834 GSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGL 655
G+LA P D C+KLPE++SL EGA+ EPL V VH R+A V P V+V GAGP+GL
Sbjct: 129 GTLAKYYTLPEDFCYKLPESISLPEGALMEPLGVAVHIVRQANVTPGQTVVVFGAGPVGL 188
Query: 654 VTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGSNV 475
+ A+AFG RI+ VD+ RL AK+ A + + + + +G
Sbjct: 189 LCCAVAKAFGAIRIIAVDIQKPRLDFAKKFAATATFEPSKAPATENATRMIAENDLGRGA 248
Query: 474 DVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY-KNT 298
DV D +G ++ T + R GG GMG M P+ A +E+++ G FRY
Sbjct: 249 DVAIDASGVEPSVHTGIHVLRPGGTYVQGGMGRSEMNFPIMAACTKELNIKGSFRYGSGD 308
Query: 297 WPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARG 178
+ L ++ + SG+I+VK LIT F ++ E AF+ G
Sbjct: 309 YKLAVQLVASGQINVKELITGIVKF--EDAEQAFKDVKTG 346
>sp|C5FTT1|XYL2_NANOT Probable D-xylulose reductase A OS=Nannizzia otae (strain
CBS 113480) GN=xdhA PE=3 SV=1
Length = 356
Score = 265 bits (677), Expect = 5e-070
Identities = 143/342 (41%), Positives = 199/342 (58%), Gaps = 4/342 (1%)
Frame = -3
Query: 1197 EEENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKE 1021
E +N++ L G+ +K + P+P L HDV V ++ GICGSDVHY F++ E
Sbjct: 5 EPKNLSFVLEGIKKVKFEDRPVPVLKDAHDVLVNVRYTGICGSDVHYWDHGSIGPFVLTE 64
Query: 1020 PMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPP 841
PMV+GHE +G++ E+G VK L VGDRVALEPGI C RC CK G+YNLC +M F ATPP
Sbjct: 65 PMVLGHESSGVVTEIGPAVKSLKVGDRVALEPGICCRRCEPCKSGKYNLCVDMVFAATPP 124
Query: 840 VHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPI 661
G+LA V P D C+KLP + L++GA+ EPL V VH R+AEV P V+V GAGP+
Sbjct: 125 YDGTLAKYYVLPEDFCYKLPSAMDLKDGALMEPLGVAVHITRQAEVKPGDTVVVFGAGPV 184
Query: 660 GLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEVEQIKKAIGS 481
GL+ A+RAFG +I+ VD+ RL AK+ A G+ + E + +G
Sbjct: 185 GLLCCAASRAFGAIKIISVDIQPERLDFAKKYAATGVFLPEKASAVENAERLRSGHGLGR 244
Query: 480 NVDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKN 301
DV D +G +++ T + R GG GMG ++ P+ A +E+++ G FRY +
Sbjct: 245 GADVVIDASGAEQSVHTGIYVARPGGTYVQGGMGRDEISFPIMAACTKELNMKGSFRYNS 304
Query: 300 -TWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARG 178
+ L LE + SG++ VK L+T F + E AFE G
Sbjct: 305 GDYKLALELVGSGRLSVKELVTKVVAF--TDAEQAFEEVKAG 344
>sp|P35497|DHSO1_YEAST Sorbitol dehydrogenase 1 OS=Saccharomyces cerevisiae
GN=SOR1 PE=1 SV=1
Length = 357
Score = 265 bits (675), Expect = 9e-070
Identities = 143/352 (40%), Positives = 211/352 (59%), Gaps = 7/352 (1%)
Frame = -3
Query: 1197 EEENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKE 1021
+ N A L + + I+ P+P++ PH V++ +KA GICGSD+HY ++ +I+K
Sbjct: 3 QNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKA 62
Query: 1020 PMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPP 841
PMV+GHE +G + EVG+ V + VGDRVA+EPG+ + KEGRYNLCP M F ATPP
Sbjct: 63 PMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPHMAFAATPP 122
Query: 840 VHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPI 661
+ G+L + P D KLPE VS EEGA EPLSVGVH+ + A V T V+V GAGP+
Sbjct: 123 IDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPV 182
Query: 660 GLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEV-EQIKKAIG 484
GL+T ARAFG ++ VDV DN+L AK GA + D ++ + ++K +G
Sbjct: 183 GLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLG 242
Query: 483 SN-VDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY 307
N DV F+C+G + + A+ T+ GG + VGMG P+ + +E+ ++G FRY
Sbjct: 243 GNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRY 302
Query: 306 K-NTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETS-ARGSNAIKVM 157
+ + + +GK++VKPLITH+F F ++ A++ + A G +K +
Sbjct: 303 SFGDYRDAVNLVATGKVNVKPLITHKFKF--EDAAKAYDYNIAHGGEVVKTI 352
>sp|Q07786|DHSO2_YEAST Sorbitol dehydrogenase 2 OS=Saccharomyces cerevisiae
GN=SOR2 PE=1 SV=1
Length = 357
Score = 262 bits (669), Expect = 4e-069
Identities = 142/352 (40%), Positives = 210/352 (59%), Gaps = 7/352 (1%)
Frame = -3
Query: 1197 EEENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFIVKE 1021
+ N A L + + I+ P+P++ PH V++ +KA GICGSD+HY ++ +I+K
Sbjct: 3 QNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKA 62
Query: 1020 PMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFATPP 841
PMV+GHE +G + EVG+ V + VGDRVA+EPG+ + KEG YNLCP M F ATPP
Sbjct: 63 PMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPP 122
Query: 840 VHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPI 661
+ G+L + P D KLPE VS EEGA EPLSVGVH+ + A V T V+V GAGP+
Sbjct: 123 IDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPV 182
Query: 660 GLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVKVTTSLEDVGFEV-EQIKKAIG 484
GL+T ARAFG ++ VDV DN+L AK GA + D ++ + ++K +G
Sbjct: 183 GLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLG 242
Query: 483 SN-VDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRY 307
N DV F+C+G + + A+ T+ GG + VGMG P+ + +E+ ++G FRY
Sbjct: 243 GNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRY 302
Query: 306 K-NTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETS-ARGSNAIKVM 157
+ + + +GK++VKPLITH+F F ++ A++ + A G +K +
Sbjct: 303 SFGDYRDAVNLVATGKVNVKPLITHKFKF--EDAAKAYDYNIAHGGEVVKTI 352
>sp|A1D9C9|XYL2_NEOFI Probable D-xylulose reductase A OS=Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) GN=xdhA PE=3
SV=1
Length = 358
Score = 262 bits (669), Expect = 4e-069
Identities = 145/348 (41%), Positives = 202/348 (58%), Gaps = 10/348 (2%)
Frame = -3
Query: 1206 SKVEEENMAAWLVGLNTLKIQPFPLPSL-GPHDVRVRMKAVGICGSDVHYLKTMRCADFI 1030
S +N++ L G++ +K + P+P L PHDV V +K GICGSDVHY + F+
Sbjct: 4 STATAQNLSFVLEGIHQVKFEDRPIPELKDPHDVLVNVKFTGICGSDVHYWEHGSIGQFV 63
Query: 1029 VKEPMVIGHECAGIIEEVGEGVKHLVVGDRVALEPGISCWRCNLCKEGRYNLCPEMKFFA 850
VK+PMV+GHE +G+I +VG V L VGDRVA+EPGI C RC CK G+YNLC +M F A
Sbjct: 64 VKDPMVLGHESSGVISKVGSAVTGLKVGDRVAMEPGIPCRRCEPCKAGKYNLCEKMAFAA 123
Query: 849 TPPVHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGA 670
TPP G+LA V P D C+KLP+N+SL+EGA+ EPL V VH R+A V P +V+V GA
Sbjct: 124 TPPYDGTLAKFYVLPEDFCYKLPDNISLQEGALMEPLGVAVHIVRQASVTPGQSVIVFGA 183
Query: 669 GPIGLVTMLAARAFGVPRIVIVDVDDNRLSVAKQLGADGIVK-VTTSLEDVGFEVEQIKK 493
GP+GL+ A+AFG +I+ VD+ RL AK+ A + S D ++++K
Sbjct: 184 GPVGLLCCAVAKAFGAAKIIAVDIQKPRLDFAKRYAATSTFEPAKVSAVD---NADRLRK 240
Query: 492 A--IGSNVDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVG 319
+G DV D +G ++ T + R GG GMG + P+ A +E+ G
Sbjct: 241 ENNLGVGADVVIDASGAEPSVHTGIHVLRPGGTYVQGGMGRSEIMFPIMAACTKELTFKG 300
Query: 318 VFRY-KNTWPLCLEFLTSGKIDVKPLITHRFGFFQKEVEDAFETSARG 178
FRY + L + + SG+++VK LIT F + E AF+ G
Sbjct: 301 SFRYGSGDYKLAVGLVASGRVNVKDLITGVVEF--HDAEQAFKEVKAG 346
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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