BLASTX 7.6.2
Query= UN21495 /QuerySize=1944
(1943 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q42806|KPYC_SOYBN Pyruvate kinase, cytosolic isozyme OS=Glyci... 872 2e-252
sp|P22200|KPYC_SOLTU Pyruvate kinase, cytosolic isozyme OS=Solan... 864 7e-250
sp|Q42954|KPYC_TOBAC Pyruvate kinase, cytosolic isozyme OS=Nicot... 765 3e-220
sp|O65595|KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme... 751 5e-216
sp|O44006|KPYK_EIMTE Pyruvate kinase OS=Eimeria tenella GN=PYK P... 438 9e-122
sp|Q92122|KPYK_XENLA Pyruvate kinase muscle isozyme OS=Xenopus l... 411 9e-114
sp|P11980|KPYM_RAT Pyruvate kinase isozymes M1/M2 OS=Rattus norv... 402 7e-111
sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapi... 401 2e-110
sp|Q12669|KPYK_ASPNG Pyruvate kinase OS=Aspergillus niger GN=pki... 400 2e-110
sp|P52480|KPYM_MOUSE Pyruvate kinase isozymes M1/M2 OS=Mus muscu... 399 4e-110
sp|P11979|KPYM_FELCA Pyruvate kinase isozyme M1 OS=Felis catus G... 399 5e-110
sp|P00548|KPYK_CHICK Pyruvate kinase muscle isozyme OS=Gallus ga... 397 2e-109
sp|Q5NVN0|KPYM_PONAB Pyruvate kinase isozyme M1 OS=Pongo abelii ... 397 2e-109
sp|P22360|KPYK_EMENI Pyruvate kinase OS=Emericella nidulans GN=p... 396 3e-109
sp|P11974|KPYM_RABIT Pyruvate kinase isozymes M1/M2 OS=Oryctolag... 395 9e-109
sp|Q29536|KPYR_CANFA Pyruvate kinase isozyme R (Fragment) OS=Can... 387 1e-106
sp|P30613|KPYR_HUMAN Pyruvate kinase isozymes R/L OS=Homo sapien... 382 4e-105
sp|O94122|KPYK_AGABI Pyruvate kinase OS=Agaricus bisporus GN=pki... 381 1e-104
sp|P53657|KPYR_MOUSE Pyruvate kinase isozymes R/L OS=Mus musculu... 378 1e-103
sp|P12928|KPYR_RAT Pyruvate kinase isozymes R/L OS=Rattus norveg... 377 2e-103
>sp|Q42806|KPYC_SOYBN Pyruvate kinase, cytosolic isozyme OS=Glycine max PE=2
SV=1
Length = 511
Score = 872 bits (2251), Expect = 2e-252
Identities = 435/511 (85%), Positives = 474/511 (92%), Gaps = 1/511 (0%)
Frame = +3
Query: 210 MSNVDIEGILK-ELPNDGRIPKTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHE 386
M+N+DIEGILK + P DGR+PKTKIVCTLGPASRSV M EKLLRAGMNVARFNFSHG+H+
Sbjct: 1 MANIDIEGILKQQQPYDGRVPKTKIVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHD 60
Query: 387 YHQGTLDNLRTAMQNTGILAAVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTDYDVLG 566
YHQ TL+NL+TAM NTGIL AV+LDTKGPEIRTG LKDG PIQLKEGQE+TITTDYD+ G
Sbjct: 61 YHQETLNNLKTAMHNTGILCAVMLDTKGPEIRTGFLKDGKPIQLKEGQEVTITTDYDIKG 120
Query: 567 DETTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVN 746
D ISMSYKKLP+ +KPGNTILC+DG+I+L VLSCDP++GTVRCRCENTA LGERKNVN
Sbjct: 121 DPEMISMSYKKLPVHLKPGNTILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVN 180
Query: 747 LPGVVVDLPTLTDKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMS 926
LPGVVVDLPTLT+KD EDI+GWGVPN IDMIALSF RKGSDLVNVRKVLG HAK+I LMS
Sbjct: 181 LPGVVVDLPTLTEKDKEDILGWGVPNKIDMIALSFVRKGSDLVNVRKVLGPHAKNIQLMS 240
Query: 927 KVENQEGVVNFDEILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQ 1106
KVENQEGV+NFDEILRETDAFMVARGDLGMEIP+EKIFLAQK+MIYKCNL GKPVVTATQ
Sbjct: 241 KVENQEGVLNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQ 300
Query: 1107 MLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSL 1286
MLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPE+AVK+MA+ICIEAESSL
Sbjct: 301 MLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMARICIEAESSL 360
Query: 1287 DYNTIFKERIRATPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVP 1466
DY IFKE IR+TP+PMSPLESLASSAVR ANK+ AKLI+VLTRGGSTAKLVAKYRPAVP
Sbjct: 361 DYGAIFKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVP 420
Query: 1467 ILSVAVPTMTTDSFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKS 1646
ILSV VP ++TDSFDW+CSDE+PARHSLIYRGLIP+L EGSAKATD ESTEVI+EAALKS
Sbjct: 421 ILSVVVPVLSTDSFDWTCSDETPARHSLIYRGLIPILGEGSAKATDAESTEVILEAALKS 480
Query: 1647 AVQRGLCNHGDAVVALHRIGVASVIKICVVK 1739
A +R LC GDAVVALHRIG ASVIKIC+VK
Sbjct: 481 ATERALCKPGDAVVALHRIGAASVIKICIVK 511
>sp|P22200|KPYC_SOLTU Pyruvate kinase, cytosolic isozyme OS=Solanum tuberosum
PE=2 SV=1
Length = 510
Score = 864 bits (2230), Expect = 7e-250
Identities = 433/510 (84%), Positives = 470/510 (92%)
Frame = +3
Query: 210 MSNVDIEGILKELPNDGRIPKTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEY 389
M+N+DI GI+K+LPNDGRIPKTKIVCTLGP+SR+VPM+EKLLRAGMNVARFNFSHG+HEY
Sbjct: 1 MANIDIAGIMKDLPNDGRIPKTKIVCTLGPSSRTVPMLEKLLRAGMNVARFNFSHGTHEY 60
Query: 390 HQGTLDNLRTAMQNTGILAAVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTDYDVLGD 569
HQ TLDNL+ AMQNT IL AV+LDTKGPEIRTG L DG PIQLKEGQEIT++TDY + G+
Sbjct: 61 HQETLDNLKIAMQNTQILCAVMLDTKGPEIRTGFLTDGKPIQLKEGQEITVSTDYTIKGN 120
Query: 570 ETTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNL 749
E ISMSYKKL +D+KPGNTILCADG+I+L VLSCDP SGTVRCRCENTA LGERKNVNL
Sbjct: 121 EEMISMSYKKLVMDLKPGNTILCADGTITLTVLSCDPPSGTVRCRCENTATLGERKNVNL 180
Query: 750 PGVVVDLPTLTDKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSK 929
PGVVVDLPTLT+KD EDI+ WGVPN+IDMIALSF RKGSDLVNVRKVLG HAK I LMSK
Sbjct: 181 PGVVVDLPTLTEKDKEDILEWGVPNNIDMIALSFVRKGSDLVNVRKVLGPHAKRIQLMSK 240
Query: 930 VENQEGVVNFDEILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQM 1109
VENQEGV+NFDEILRETD+FMVARGDLGMEIP+EKIFLAQK+MIYKCNLAGK VVTATQM
Sbjct: 241 VENQEGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLAGKAVVTATQM 300
Query: 1110 LESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLD 1289
LESMIKSP PTRAEATDVANAVLDGTDCVMLSGESAAGAYPE+AVK+M++ICIEAESSLD
Sbjct: 301 LESMIKSPAPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMSRICIEAESSLD 360
Query: 1290 YNTIFKERIRATPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPI 1469
IFKE IR TP+PMSPLESLASSAVR ANK+ AKLI+VLTRGGSTAKLVAKYRPAVPI
Sbjct: 361 NEAIFKEMIRCTPLPMSPLESLASSAVRTANKARAKLIVVLTRGGSTAKLVAKYRPAVPI 420
Query: 1470 LSVAVPTMTTDSFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSA 1649
LSV VP +TTDSFDWS SDE+PARHSL+YRGLIP+L EGSAKATD ESTEVI+EAALKSA
Sbjct: 421 LSVVVPVLTTDSFDWSISDETPARHSLVYRGLIPLLGEGSAKATDSESTEVILEAALKSA 480
Query: 1650 VQRGLCNHGDAVVALHRIGVASVIKICVVK 1739
V RGLC GDAVVALHRIG ASVIKICVVK
Sbjct: 481 VTRGLCKPGDAVVALHRIGSASVIKICVVK 510
>sp|Q42954|KPYC_TOBAC Pyruvate kinase, cytosolic isozyme OS=Nicotiana tabacum
PE=2 SV=1
Length = 508
Score = 765 bits (1974), Expect = 3e-220
Identities = 382/491 (77%), Positives = 429/491 (87%)
Frame = +3
Query: 267 PKTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTGILA 446
PKTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSH+YHQ T+DNLR AM++TGIL
Sbjct: 18 PKTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHDYHQETIDNLRQAMESTGILC 77
Query: 447 AVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTDYDVLGDETTISMSYKKLPLDVKPGN 626
AV+LDTKGPEIRTG LKD P+QLK+GQEITI+TDY + GDE+ I MSYKKL DVKP +
Sbjct: 78 AVMLDTKGPEIRTGFLKDAKPVQLKQGQEITISTDYSIKGDESMICMSYKKLAEDVKPQS 137
Query: 627 TILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLTDKDIEDIM 806
ILCADG I+ VLSCD E+G RCRCENTA+LGERKNVNLPGV+VDLPTLTDKD +DI+
Sbjct: 138 VILCADGQITFTVLSCDKENGLDRCRCENTAVLGERKNVNLPGVIVDLPTLTDKDKDDIL 197
Query: 807 GWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFDEILRETDA 986
WGVPN IDMIALSF RKGSDLV VRK+LG HAK+I+LMSKVENQEGV NFD+IL +DA
Sbjct: 198 NWGVPNHIDMIALSFVRKGSDLVEVRKLLGEHAKNILLMSKVENQEGVANFDDILLNSDA 257
Query: 987 FMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 1166
FMVARGDLGMEIPIEKIFLAQK+MIYKCN+ GKPVVTATQMLESMIKSPRPTRAEATDVA
Sbjct: 258 FMVARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVA 317
Query: 1167 NAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRATPVPMSPL 1346
NAVLDGTDCVMLSGE+AAGAYP++AV MAKICIEAES++DY +FK + PVPMSPL
Sbjct: 318 NAVLDGTDCVMLSGETAAGAYPDLAVGTMAKICIEAESTIDYPDVFKRIMSNAPVPMSPL 377
Query: 1347 ESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTDSFDWSCSD 1526
ESLASSAVR AN + A LI+VLTRGGSTAKLVAKYRP +PILSV VP + TDSFDW+CSD
Sbjct: 378 ESLASSAVRTANSAKAALILVLTRGGSTAKLVAKYRPGMPILSVVVPEIKTDSFDWTCSD 437
Query: 1527 ESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDAVVALHRIG 1706
ESPARHSLI+RGL+P+L GSA+A+ ESTE ++ AL+ A +GLC GD+VVALHR+G
Sbjct: 438 ESPARHSLIFRGLVPVLHAGSARASHEESTEEALDFALQHAKTKGLCKQGDSVVALHRVG 497
Query: 1707 VASVIKICVVK 1739
ASVIKI VK
Sbjct: 498 TASVIKIVTVK 508
>sp|O65595|KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme OS=Arabidopsis
thaliana GN=At4g26390 PE=2 SV=1
Length = 497
Score = 751 bits (1938), Expect = 5e-216
Identities = 380/491 (77%), Positives = 425/491 (86%)
Frame = +3
Query: 267 PKTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTGILA 446
PKTKIVCTLGPASRSVPM+EKLL AGM+VARFNFSHGS+EYHQ TLDNLR AM NTG+L
Sbjct: 7 PKTKIVCTLGPASRSVPMVEKLLMAGMSVARFNFSHGSYEYHQETLDNLRQAMLNTGMLC 66
Query: 447 AVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTDYDVLGDETTISMSYKKLPLDVKPGN 626
AV+LDTKGPEIRTG LKDG PIQLK+GQEITI+TDYD+ GDE TI MSYKKL DV PG
Sbjct: 67 AVMLDTKGPEIRTGFLKDGKPIQLKQGQEITISTDYDLKGDEKTICMSYKKLAQDVNPGM 126
Query: 627 TILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLTDKDIEDIM 806
ILCADG+ISL VLSCD E GTVRCRCENT+MLGERKNVNLPGVVVDLPTLT+KD +DI+
Sbjct: 127 VILCADGTISLKVLSCDKEKGTVRCRCENTSMLGERKNVNLPGVVVDLPTLTEKDKQDIL 186
Query: 807 GWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFDEILRETDA 986
WGVPN IDMIALSF RKGSDLV VRK+LG HAK+I+LMSKVENQEGV NFD+IL +DA
Sbjct: 187 EWGVPNQIDMIALSFVRKGSDLVQVRKLLGKHAKTILLMSKVENQEGVANFDDILINSDA 246
Query: 987 FMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 1166
FM+ARGDLGMEIPIEKIFLAQK+MIYKCN GKPVVTATQMLESMIKSPRPTRAEATDVA
Sbjct: 247 FMIARGDLGMEIPIEKIFLAQKVMIYKCNFMGKPVVTATQMLESMIKSPRPTRAEATDVA 306
Query: 1167 NAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRATPVPMSPL 1346
NAVLDGTDCVMLSGE+AAGAYPE+AV+ MAKIC+EAES+LDY IFK + VPMSP+
Sbjct: 307 NAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDIFKRIMLHAAVPMSPM 366
Query: 1347 ESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTDSFDWSCSD 1526
ESLASSAVR A S A L++VLTRGGSTA+LVAKYRP +PILSV VP +T+DSFDW+CS+
Sbjct: 367 ESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVVVPEITSDSFDWACSN 426
Query: 1527 ESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDAVVALHRIG 1706
E+PARHSLIYRGL+P+L GSA+A+ ESTE +E A + ++ LC GD+VVAL R G
Sbjct: 427 EAPARHSLIYRGLVPVLYAGSARASIDESTEETLEFASEYGKKKQLCKTGDSVVALFRTG 486
Query: 1707 VASVIKICVVK 1739
A VIKI VK
Sbjct: 487 NAIVIKILTVK 497
>sp|O44006|KPYK_EIMTE Pyruvate kinase OS=Eimeria tenella GN=PYK PE=2 SV=1
Length = 531
Score = 438 bits (1125), Expect = 9e-122
Identities = 220/410 (53%), Positives = 294/410 (71%), Gaps = 3/410 (0%)
Frame = +3
Query: 270 KTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAM-QNTGILA 446
+TKIVCT+GP+ V + +L+ AGMNV R NFSHG HE H + NL+ A+ Q G
Sbjct: 57 RTKIVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGKRV 116
Query: 447 AVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTDYDVLGDETTISMSYKKLPLDVKPGN 626
A++LDTKGPEIRTG L+ PI+L G + I TDY +G+++ I+ SY+KLP VKPGN
Sbjct: 117 ALLLDTKGPEIRTGMLEGDKPIELHAGDMLKIVTDYSFVGNKSCIACSYEKLPSSVKPGN 176
Query: 627 TILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLTDKDIEDIM 806
TIL ADGS+S+ V+ C + V R N A++G +KN+NLPGV VDLP + +KD DI+
Sbjct: 177 TILIADGSLSVEVVECGKD--YVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGEKDKNDIL 234
Query: 807 GWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFDEILRETDA 986
+G+P + IA SF + D+ +R +LG+ ++I ++ K+EN EG++NFDEIL+E D
Sbjct: 235 NFGIPMGCNFIAASFVQSADDVRYIRSILGTKGRNIKIIPKIENVEGLLNFDEILQEADG 294
Query: 987 FMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 1166
M+ARGDLGMEIP EK+FLAQK+MI KCN+AGKPV+TATQMLESM K+PRPTRAEA DVA
Sbjct: 295 IMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMTKNPRPTRAEAADVA 354
Query: 1167 NAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRATPVPMSPL 1346
NAVLDGTDCVMLSGE+A G++P AV VM+++C EAE +DY +F+ +AT P+
Sbjct: 355 NAVLDGTDCVMLSGETANGSFPVQAVTVMSRVCFEAEGCIDYQQVFRATCQATMTPIDTQ 414
Query: 1347 ESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMT 1496
E++A +AV A +A LI+ LT G TA+L+AKYRP PIL+++ T
Sbjct: 415 EAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILALSASEET 464
>sp|Q92122|KPYK_XENLA Pyruvate kinase muscle isozyme OS=Xenopus laevis GN=pkm
PE=2 SV=1
Length = 527
Score = 411 bits (1056), Expect = 9e-114
Identities = 228/484 (47%), Positives = 305/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTGI---- 440
T I+CT+GPASRSV M+++++++GMN+AR NFSHG+HEYH GT+ N+R A ++
Sbjct: 41 TGIICTIGPASRSVEMLKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESLASNPIH 100
Query: 441 --LAAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
AV LDTKGPEIRTG +K ++LK+G + IT D + DE + + YK L
Sbjct: 101 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATMRITLDDAFQENCDENVLWVDYKNL 160
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
VKPG+ I DG ISL V P+ EN MLG +K VNLPG VDLP ++
Sbjct: 161 TKVVKPGSKIYVDDGLISLLVKEIGPDFCVT--EIENGGMLGSKKGVNLPGAAVDLPAVS 218
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
KDI+D+ +GV +DM+ SF RK +D+ VR+VLG K+I ++SK+EN EGV FD
Sbjct: 219 SKDIQDLQ-FGVEQDVDMVFASFIRKAADVHEVREVLGEKGKNIKIISKIENHEGVRRFD 277
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CN AGKPV+ ATQMLESMIK PRPT
Sbjct: 278 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 337
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + +F+E R
Sbjct: 338 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQLFEELRRV 397
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
+P+ P E+ A AV A+ K + IIVLT+ G +A L+++YRP PI+SV T
Sbjct: 398 SPLTRDPTEATAVGAVEASFKCSSGAIIVLTKSGRSAHLLSRYRPRAPIISVTRNGQT-- 455
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + +YRG+ P+L + E + + A+ RG GD
Sbjct: 456 -----------ARQAHLYRGIFPVLYREAVHEAWAEDVDSRVNFAMDIGKARGFFKSGDV 504
Query: 1683 VVAL 1694
V+ L
Sbjct: 505 VIVL 508
>sp|P11980|KPYM_RAT Pyruvate kinase isozymes M1/M2 OS=Rattus norvegicus GN=Pkm2
PE=1 SV=3
Length = 531
Score = 402 bits (1031), Expect = 7e-111
Identities = 227/484 (46%), Positives = 307/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTG---IL 443
T I+CT+GPASRSV M+++++++GMNVAR NFSHG+HEYH T+ N+R A ++ IL
Sbjct: 45 TGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPIL 104
Query: 444 ---AAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
AV LDTKGPEIRTG +K ++LK+G + IT D Y DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V+ G+ I DG ISL V + + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVEVGSKIYVDDGLISLQVK--EKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVS 222
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
+KDI+D+ +GV +DM+ SF RK +D+ VRKVLG K+I ++SK+EN EGV FD
Sbjct: 223 EKDIQDLK-FGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFD 281
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CN AGKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + +F+E RA
Sbjct: 342 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARA 401
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
+ PLE++A +V A+ K A +IVLT G +A VA+YRP PI++V T
Sbjct: 402 SSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQT-- 459
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + +YRG+ P+L + + E ++ + A+ RG GD
Sbjct: 460 -----------ARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDV 508
Query: 1683 VVAL 1694
V+ L
Sbjct: 509 VIVL 512
>sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapiens GN=PKM2
PE=1 SV=4
Length = 531
Score = 401 bits (1028), Expect = 2e-110
Identities = 228/484 (47%), Positives = 305/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTG---IL 443
T I+CT+GPASRSV +++++++GMNVAR NFSHG+HEYH T+ N+RTA ++ IL
Sbjct: 45 TGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPIL 104
Query: 444 ---AAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
AV LDTKGPEIRTG +K ++LK+G + IT D Y DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V+ G+ I DG ISL V + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVEVGSKIYVDDGLISLQVK--QKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVS 222
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
+KDI+D+ +GV +DM+ SF RK SD+ VRKVLG K+I ++SK+EN EGV FD
Sbjct: 223 EKDIQDLK-FGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFD 281
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CN AGKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + +F+E R
Sbjct: 342 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRL 401
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
P+ P E+ A AV A+ K + IIVLT+ G +A VA+YRP PI++V T
Sbjct: 402 APITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQT-- 459
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + +YRG+ P+L + + E ++ + A+ RG GD
Sbjct: 460 -----------ARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDV 508
Query: 1683 VVAL 1694
V+ L
Sbjct: 509 VIVL 512
>sp|Q12669|KPYK_ASPNG Pyruvate kinase OS=Aspergillus niger GN=pkiA PE=3 SV=1
Length = 526
Score = 400 bits (1027), Expect = 2e-110
Identities = 207/406 (50%), Positives = 274/406 (67%), Gaps = 5/406 (1%)
Frame = +3
Query: 270 KTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQ-NTGILA 446
+T I+ T+GP + SV I L AG+NV R NFSHGS++YHQ +DN R A + G
Sbjct: 34 RTSIIGTIGPKTNSVEKINSLRTAGLNVVRMNFSHGSYQYHQSVIDNAREAAKTQVGRPL 93
Query: 447 AVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTD--YDVLGDETTISMSYKKLPLDVKP 620
A+ LDTKGPEIRTG+ D I +K+G E+ ITTD Y D+ + + YK + + P
Sbjct: 94 AIALDTKGPEIRTGNTPDDKDIPIKQGHELNITTDEQYATASDDKNMYLDYKNITKVISP 153
Query: 621 GNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLTDKDIED 800
G I DG +S VL + T+R RC N + RK VNLPG VDLP L++KDI D
Sbjct: 154 GKLIYVDDGILSFEVLEV-VDDKTIRVRCLNNGNISSRKGVNLPGTDVDLPALSEKDIAD 212
Query: 801 IMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFDEILRET 980
+ +GV N +DM+ SF R+GSD+ ++R+VLG K I +++K+ENQ+GV NFDEIL ET
Sbjct: 213 LK-FGVRNKVDMVFASFIRRGSDIRHIREVLGEEGKEIQIIAKIENQQGVNNFDEILEET 271
Query: 981 DAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATD 1160
D MVARGDLG+EIP K+F+AQK+MI KCN+ GKPV+ ATQMLESM +PRPTRAE +D
Sbjct: 272 DGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSD 331
Query: 1161 VANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRATPVPMS 1340
VANAVLDG DCVMLSGE+A G YP AVK+M++ C+ AE ++ + +F E P P
Sbjct: 332 VANAVLDGADCVMLSGETAKGNYPNEAVKMMSETCLLAEVAIPHFNVFDELRNLAPRPTD 391
Query: 1341 PLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSV 1478
+ES+A +AV A+ + +A I+VLT G TA+ ++KYRP PI+ V
Sbjct: 392 TVESIAMAAVSASLELNAGAIVVLTTSGKTARYLSKYRPVCPIVMV 437
>sp|P52480|KPYM_MOUSE Pyruvate kinase isozymes M1/M2 OS=Mus musculus GN=Pkm2
PE=1 SV=4
Length = 531
Score = 399 bits (1025), Expect = 4e-110
Identities = 227/484 (46%), Positives = 306/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTG---IL 443
T I+CT+GPASRSV M+++++++GMNVAR NFSHG+HEYH T+ N+R A ++ IL
Sbjct: 45 TGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPIL 104
Query: 444 ---AAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
AV LDTKGPEIRTG +K ++LK+G + IT D Y DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V+ G+ I DG ISL V + + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVEVGSKIYVDDGLISLQVK--EKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVS 222
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
+KDI+D+ +GV +DM+ SF RK +D+ VRKVLG K+I ++SK+EN EGV FD
Sbjct: 223 EKDIQDLK-FGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFD 281
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CN AGKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + +F+E R
Sbjct: 342 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRL 401
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
P+ P E+ A AV A+ K + IIVLT+ G +A VA+YRP PI++V T
Sbjct: 402 APITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQT-- 459
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + +YRG+ P+L + + E ++ + A+ RG GD
Sbjct: 460 -----------ARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAMDVGKARGFFKKGDV 508
Query: 1683 VVAL 1694
V+ L
Sbjct: 509 VIVL 512
>sp|P11979|KPYM_FELCA Pyruvate kinase isozyme M1 OS=Felis catus GN=PKM2 PE=1
SV=2
Length = 531
Score = 399 bits (1024), Expect = 5e-110
Identities = 220/484 (45%), Positives = 305/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTGI---- 440
T I+CT+GPASRSV ++++++++GMNVAR NFSHG+HEYH T+ N+R A ++
Sbjct: 45 TGIICTIGPASRSVEILKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPIR 104
Query: 441 --LAAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
AV LDTKGPEIRTG +K ++LK+G + IT D Y DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNI 164
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V+ G+ + DG ISL V + + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVEVGSKVYVDDGLISLLVK--EKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVS 222
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
+KDI+D+ +GV +DM+ SF RK SD+ VRKVLG K+I ++SK+EN EGV FD
Sbjct: 223 EKDIQDLK-FGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFD 281
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CN AGKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + +F+E +R
Sbjct: 342 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRG 401
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
+ +E++A +V A+ K A +IVLT G +A VA+YRP PI++V
Sbjct: 402 SSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT------- 454
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
+ AR + +YRG+ P++ + + E ++ + A+ RG HGD
Sbjct: 455 ------RNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKHGDV 508
Query: 1683 VVAL 1694
V+ L
Sbjct: 509 VIVL 512
>sp|P00548|KPYK_CHICK Pyruvate kinase muscle isozyme OS=Gallus gallus GN=PKM2
PE=2 SV=2
Length = 530
Score = 397 bits (1019), Expect = 2e-109
Identities = 219/484 (45%), Positives = 306/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQN------T 434
T I+CT+GPASRSV +++++++GMNVAR NFSHG+HEYH+GT+ N+R A ++ T
Sbjct: 44 TGIICTIGPASRSVDKLKEMIKSGMNVARLNFSHGTHEYHEGTIKNVREATESFASDPIT 103
Query: 435 GILAAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTDYDVLG--DETTISMSYKKL 602
A+ LDTKGPEIRTG +K ++LK+G + +T D + DE + + YK L
Sbjct: 104 YRPVAIALDTKGPEIRTGLIKGSGTAEVELKKGAALKVTLDNAFMENCDENVLWVDYKNL 163
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
+ G+ I DG ISL V + V EN MLG +K VNLPG VDLP ++
Sbjct: 164 IKVIDVGSKIYVDDGLISLLVK--EKGKDFVMTEVENGGMLGSKKGVNLPGAAVDLPAVS 221
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
+KDI+D+ +GV ++DM+ SF RK +D+ VRKVLG K I ++SK+EN EGV FD
Sbjct: 222 EKDIQDLK-FGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKHIKIISKIENHEGVRRFD 280
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EI+ +D MVARGDLG+EIP EK+FLAQK+MI +CN AGKP++ ATQMLESMIK PRPT
Sbjct: 281 EIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPT 340
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + F+E +R
Sbjct: 341 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAMFHRQQFEEILRH 400
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
+ P +++A+ AV A+ K A +IV+T G +A LV++YRP PI++V
Sbjct: 401 SVHHREPADAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVT------- 453
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
++ AR + +YRG+ P+L + A E ++ + + RG GD
Sbjct: 454 ------RNDQTARQAHLYRGVFPVLCKQPAHDAWAEDVDLRVNLGMNVGKARGFFKTGDL 507
Query: 1683 VVAL 1694
V+ L
Sbjct: 508 VIVL 511
>sp|Q5NVN0|KPYM_PONAB Pyruvate kinase isozyme M1 OS=Pongo abelii GN=PKM2 PE=2
SV=3
Length = 531
Score = 397 bits (1018), Expect = 2e-109
Identities = 225/484 (46%), Positives = 305/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTG---IL 443
T I+CT+GPASRSV +++++++GMNVAR NFSHG+HEYH T+ N+RTA ++ IL
Sbjct: 45 TGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPIL 104
Query: 444 ---AAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
AV LDTKGPEIRTG +K ++LK+G + IT D Y DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V+ G+ I DG ISL V + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVEVGSKIYVDDGLISLQVK--QKGADFLLTEVENGGSLGSKKGVNLPGAAVDLPAVS 222
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
+KDI+D+ +GV +DM+ SF RK SD+ VRKVLG K+I ++SK+EN EGV FD
Sbjct: 223 EKDIQDLK-FGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFD 281
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CN AGKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE + VANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + +F+E +RA
Sbjct: 342 RAEGSGVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRA 401
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
+ +E++A +V A+ K A +IVLT G +A VA+YRP PI++V T
Sbjct: 402 SSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQT-- 459
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + +YRG+ P+L + + E ++ + A+ RG GD
Sbjct: 460 -----------ARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDV 508
Query: 1683 VVAL 1694
V+ L
Sbjct: 509 VIVL 512
>sp|P22360|KPYK_EMENI Pyruvate kinase OS=Emericella nidulans GN=pkiA PE=3 SV=2
Length = 526
Score = 396 bits (1017), Expect = 3e-109
Identities = 205/407 (50%), Positives = 275/407 (67%), Gaps = 5/407 (1%)
Frame = +3
Query: 270 KTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTA-MQNTGILA 446
+T I+CT+GP + SV I L RAG+NV R NFSHGS+EYHQ +D+ R A Q G
Sbjct: 34 RTSIICTIGPKTNSVEKINALRRAGLNVVRMNFSHGSYEYHQSVIDHAREAEKQQAGRPV 93
Query: 447 AVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTD--YDVLGDETTISMSYKKLPLDVKP 620
A+ LDTKGPEIRTG+ I +K G E+ I+TD Y D+ + + YK + +
Sbjct: 94 AIALDTKGPEIRTGNTVGDKDIPIKAGHEMNISTDEQYATASDDQNMYVDYKNITKVISA 153
Query: 621 GNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLTDKDIED 800
G I DG +S VL + T+R RC N + RK VNLPG VDLP L++KDI D
Sbjct: 154 GKLIYVDDGILSFEVLEV-VDDKTLRVRCLNNGNISSRKGVNLPGTDVDLPALSEKDISD 212
Query: 801 IMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFDEILRET 980
+ +GV N +DM+ SF R+GSD+ ++R+VLG + I +++K+ENQ+GV NFDEIL ET
Sbjct: 213 LK-FGVKNKVDMVFASFIRRGSDIRHIREVLGEEGREIQIIAKIENQQGVNNFDEILEET 271
Query: 981 DAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATD 1160
D MVARGDLG+EIP K+F+AQK+MI KCN+ GKPV+ ATQMLESM +PRPTRAE +D
Sbjct: 272 DGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSD 331
Query: 1161 VANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRATPVPMS 1340
VANAVLDG DCVMLSGE+A G YP AV +M++ C+ AE ++ + +F E P P
Sbjct: 332 VANAVLDGADCVMLSGETAKGNYPCEAVTMMSETCLLAEVAIPHFNVFDELRNLAPRPTD 391
Query: 1341 PLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVA 1481
+ES+A +AV A+ + +A I+VLT G+TA++++KYRP PI+ V+
Sbjct: 392 TVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMVS 438
>sp|P11974|KPYM_RABIT Pyruvate kinase isozymes M1/M2 OS=Oryctolagus cuniculus
GN=PKM2 PE=1 SV=4
Length = 531
Score = 395 bits (1013), Expect = 9e-109
Identities = 220/484 (45%), Positives = 305/484 (63%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTG---IL 443
T I+CT+GPASRSV +++++++GMNVAR NFSHG+HEYH T+ N+RTA ++ IL
Sbjct: 45 TGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPIL 104
Query: 444 ---AAVVLDTKGPEIRTGSLKDGN--PIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
AV LDTKGPEIRTG +K ++LK+G + IT D Y DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V G+ + DG ISL V P+ + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVDVGSKVYVDDGLISLQVKQKGPD--FLVTEVENGGFLGSKKGVNLPGAAVDLPAVS 222
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
+KDI+D+ +GV +DM+ SF RK +D+ VRK+LG K+I ++SK+EN EGV FD
Sbjct: 223 EKDIQDLK-FGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFD 281
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK++I +CN AGKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G YP AV++ I EAE+++ + +F+E R+
Sbjct: 342 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARS 401
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
+ +E++A +V A+ K A +IVLT G +A VA+YRP PI++V
Sbjct: 402 SSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT------- 454
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
+ AR + +YRG+ P++ + + E ++ + A+ RG GD
Sbjct: 455 ------RNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDV 508
Query: 1683 VVAL 1694
V+ L
Sbjct: 509 VIVL 512
>sp|Q29536|KPYR_CANFA Pyruvate kinase isozyme R (Fragment) OS=Canis familiaris
GN=PKLR PE=2 SV=1
Length = 519
Score = 387 bits (994), Expect = 1e-106
Identities = 215/484 (44%), Positives = 303/484 (62%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNTGIL--- 443
T I+ T+GPAS SV ++++++AGMN+AR NFSHGSHEYH ++ N+R A+++
Sbjct: 33 TSIIATIGPASHSVERLKEMIKAGMNIARLNFSHGSHEYHAQSIANIREAVESFATSPLG 92
Query: 444 ---AAVVLDTKGPEIRTGSLKDG--NPIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
A+ LDTKGPEIRTG LK G ++L +G + +T D + LGD T+ + Y +
Sbjct: 93 YRPVAIALDTKGPEIRTGVLKGGPETEVELVKGSWVLVTVDPAFRTLGDAHTVWVDYPNI 152
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V G I DG ISL V D + + + EN +LG RK VNLPG VDLP L+
Sbjct: 153 VKVVPVGGRIFIDDGLISLQVKKIDRKG--LETQVENGGLLGSRKGVNLPGAEVDLPGLS 210
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
++D +D+ +GV +++D++ SF RK SD+ +R LG ++I ++SK+EN EGV FD
Sbjct: 211 EQDAQDLR-FGVEHNVDIVFASFVRKASDVAAIRAALGPEGRTIKIISKIENHEGVKKFD 269
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CNLAGKPVV ATQMLESMI PRPT
Sbjct: 270 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPT 329
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G +P AVK+ +I EAE+++ + +F+E RA
Sbjct: 330 RAETSDVANAVLDGADCIMLSGETAKGKFPVEAVKMQHRIAREAEAAVYHRQLFEELRRA 389
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
P+ P E A + V AA K A IIVLT+ G +A+L+++YRP +++V
Sbjct: 390 APLSRDPTEVTAIATVEAAFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVT------- 442
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + + RG+ P+L +A + + ++ ++S RG GD
Sbjct: 443 ------RSAQAARQAHLCRGVFPLLYSEPPEAIWADDVDRRVQFGIESGKLRGFLRVGDL 496
Query: 1683 VVAL 1694
V+ +
Sbjct: 497 VIVV 500
>sp|P30613|KPYR_HUMAN Pyruvate kinase isozymes R/L OS=Homo sapiens GN=PKLR PE=1
SV=2
Length = 574
Score = 382 bits (981), Expect = 4e-105
Identities = 216/484 (44%), Positives = 300/484 (61%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQN------T 434
T I+ T+GPASRSV ++++++AGMN+AR NFSHGSHEYH ++ N+R A+++ +
Sbjct: 88 TSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLS 147
Query: 435 GILAAVVLDTKGPEIRTGSLKDG--NPIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
A+ LDTKGPEIRTG L+ G + ++L +G ++ +T D + G+ T+ + Y +
Sbjct: 148 YRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNI 207
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V G I DG ISL V PE + + EN +LG RK VNLPG VDLP L+
Sbjct: 208 VRVVPVGGRIYIDDGLISLVVQKIGPEG--LVTQVENGGVLGSRKGVNLPGAQVDLPGLS 265
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
++D+ D+ +GV + +D++ SF RK SD+ VR LG I ++SK+EN EGV FD
Sbjct: 266 EQDVRDLR-FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFD 324
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CNLAGKPVV ATQMLESMI PRPT
Sbjct: 325 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPT 384
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G +P AVK+ I EAE+++ + +F+E RA
Sbjct: 385 RAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRA 444
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
P+ P E A AV AA K A IIVLT G +A+L+++YRP +++V
Sbjct: 445 APLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVT------- 497
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + RG+ P+L +A + + ++ ++S RG GD
Sbjct: 498 ------RSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDL 551
Query: 1683 VVAL 1694
V+ +
Sbjct: 552 VIVV 555
>sp|O94122|KPYK_AGABI Pyruvate kinase OS=Agaricus bisporus GN=pkiA PE=2 SV=1
Length = 532
Score = 381 bits (978), Expect = 1e-104
Identities = 199/407 (48%), Positives = 269/407 (66%), Gaps = 7/407 (1%)
Frame = +3
Query: 270 KTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQNT--GIL 443
KT I+ T+GP +V + + AG+N+ R NFSHG+HEYHQ +DN R ++N G
Sbjct: 34 KTAIIATIGPKINTVEKLTDVRLAGVNIVRMNFSHGTHEYHQSVIDNTRQMIKNDPHGRP 93
Query: 444 AAVVLDTKGPEIRTGSLKDGNPIQLKEGQEITITTD--YDVLGDETTISMSYKKLPLDVK 617
A+ LDTKGPEIRTG +DGN +K G E +TTD Y + D + + Y L
Sbjct: 94 VAIALDTKGPEIRTGQTRDGNDYPIKAGDEFIVTTDPKYSDICDNKVLFVDYANLASVTA 153
Query: 618 PGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLTDKDIE 797
PG I DG ISL +LS D + R N L RK VNLP VDLP L++KD +
Sbjct: 154 PGKLIYIDDGIISLLILSID--GMNLHVRALNNGTLSSRKGVNLPKTDVDLPPLSEKDKD 211
Query: 798 DIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFDEILRE 977
D+ +G+ N +DMI SF R+G D+ +R+VLG SI ++ K+EN++GV NFDEIL+E
Sbjct: 212 DLR-FGIRNGVDMIFASFIRRGEDVRQIREVLGPDGASIKIIVKIENEQGVANFDEILKE 270
Query: 978 TDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEAT 1157
D MVARGDLG+EIP ++FLAQK+MI KCN+ GKPV+ ATQMLESM +PRPTRAE +
Sbjct: 271 ADGVMVARGDLGIEIPASQVFLAQKMMIAKCNIVGKPVIVATQMLESMTYNPRPTRAEVS 330
Query: 1158 DVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRATPVPM 1337
DVANAVLDG+DCVMLSGE+A G+YP +V +MA+ C+ AE+++ Y ++ + P
Sbjct: 331 DVANAVLDGSDCVMLSGETAKGSYPVQSVLMMAETCLLAETAICYPPLYDDLRAVQARPT 390
Query: 1338 SPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSV 1478
E++A +AV AA + AK ++VL+ G TA+LV+KYRP +PI++V
Sbjct: 391 ETAETVAIAAVAAAAEQDAKALLVLSTSGETARLVSKYRPKIPIITV 437
>sp|P53657|KPYR_MOUSE Pyruvate kinase isozymes R/L OS=Mus musculus GN=Pklr PE=2
SV=1
Length = 574
Score = 378 bits (969), Expect = 1e-103
Identities = 215/484 (44%), Positives = 301/484 (62%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQN--TGILA 446
T I+ T+GPASRSV ++++++AGMN+AR NFSHGSHEYH ++ N+R A ++ T L+
Sbjct: 88 TSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLS 147
Query: 447 ----AVVLDTKGPEIRTGSLKDG--NPIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
A+ LDTKGPEIRTG L+ G + +++ +G ++ +T D + GD T+ + Y +
Sbjct: 148 YRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNI 207
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V G I DG ISL V PE + E+ LG RK VNLP VDLP L+
Sbjct: 208 TQVVAVGGRIYIDDGLISLVVRKIGPEG--LVTEVEHGGFLGNRKGVNLPNAEVDLPGLS 265
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
++D+ D+ +GV + +D+I SF RK SD+V VR LG + I ++SK+EN EGV FD
Sbjct: 266 EQDLLDLR-FGVEHYVDIIFASFVRKASDVVAVRDALGPEGRGIKIISKIENHEGVKKFD 324
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D M+ARGDLG+EIP EK+FLAQK+MI +CNLAGKPVV ATQMLESMI RPT
Sbjct: 325 EILEVSDGIMMARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPT 384
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G++P AVK+ I EAE+++ + +F+E RA
Sbjct: 385 RAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQLFEELRRA 444
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
P+ P E A AV A+ K A IIVLT+ G +A+L+++YRP +++V
Sbjct: 445 APLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVT------- 497
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + RG+ P+L +A + + ++ ++S RG GD
Sbjct: 498 ------RSAQAARQVHLSRGVFPLLYREPPEAVWADDVDRRVQFGIESGKLRGFLRVGDL 551
Query: 1683 VVAL 1694
V+ +
Sbjct: 552 VIVV 555
>sp|P12928|KPYR_RAT Pyruvate kinase isozymes R/L OS=Rattus norvegicus GN=Pklr
PE=2 SV=2
Length = 574
Score = 377 bits (967), Expect = 2e-103
Identities = 214/484 (44%), Positives = 303/484 (62%), Gaps = 26/484 (5%)
Frame = +3
Query: 273 TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQGTLDNLRTAMQN--TGILA 446
T I+ T+GPASRSV ++++++AGMN+AR NFSHGSHEYH ++ N+R A ++ T L+
Sbjct: 88 TSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLS 147
Query: 447 ----AVVLDTKGPEIRTGSLKDG--NPIQLKEGQEITITTD--YDVLGDETTISMSYKKL 602
A+ LDTKGPEIRTG L+ G + +++ +G ++ +T D + GD T+ + Y +
Sbjct: 148 YRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNI 207
Query: 603 PLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENTAMLGERKNVNLPGVVVDLPTLT 782
V G I DG ISL V PE + E+ +LG RK VNLP VDLP L+
Sbjct: 208 TRVVAVGGRIYIDDGLISLVVQKIGPEG--LVTEVEHGGILGSRKGVNLPNTEVDLPGLS 265
Query: 783 DKDIEDIMGWGVPNSIDMIALSFFRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVVNFD 962
++D+ D+ +GV +++D+I SF RK SD++ VR LG ++I ++SK+EN EGV FD
Sbjct: 266 EQDLLDLR-FGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFD 324
Query: 963 EILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPT 1142
EIL +D MVARGDLG+EIP EK+FLAQK+MI +CNLAGKPVV ATQMLESMI RPT
Sbjct: 325 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPT 384
Query: 1143 RAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKERIRA 1322
RAE +DVANAVLDG DC+MLSGE+A G++P AV + I EAE+++ + +F+E RA
Sbjct: 385 RAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRA 444
Query: 1323 TPVPMSPLESLASSAVRAANKSHAKLIIVLTRGGSTAKLVAKYRPAVPILSVAVPTMTTD 1502
P+ P E A AV A+ K A IIVLT+ G +A+L+++YRP +++V
Sbjct: 445 APLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVT------- 497
Query: 1503 SFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDIESTEVIIEAALKSAVQRGLCNHGDA 1682
AR + RG+ P+L +A + + ++ ++S RG GD
Sbjct: 498 ------RSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDL 551
Query: 1683 VVAL 1694
V+ +
Sbjct: 552 VIVV 555
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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