BLASTX 7.6.2
Query= UN21542 /QuerySize=1471
(1470 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O15270|SPTC2_HUMAN Serine palmitoyltransferase 2 OS=Homo sapi... 416 2e-115
sp|P97363|SPTC2_MOUSE Serine palmitoyltransferase 2 OS=Mus muscu... 415 6e-115
sp|O54694|SPTC2_CRIGR Serine palmitoyltransferase 2 OS=Cricetulu... 413 2e-114
sp|Q54EX5|SPTC2_DICDI Serine palmitoyltransferase 2 OS=Dictyoste... 403 3e-111
sp|Q9NUV7|SPTC3_HUMAN Serine palmitoyltransferase 3 OS=Homo sapi... 394 1e-108
sp|Q8BG54|SPTC3_MOUSE Serine palmitoyltransferase 3 OS=Mus muscu... 368 6e-101
sp|Q09925|LCB2_SCHPO Serine palmitoyltransferase 2 OS=Schizosacc... 362 4e-099
sp|P40970|LCB2_YEAST Serine palmitoyltransferase 2 OS=Saccharomy... 350 2e-095
sp|P48241|LCB2_KLULA Serine palmitoyltransferase 2 OS=Kluyveromy... 332 6e-090
sp|B8J3V0|BIOF_DESDA 8-amino-7-oxononanoate synthase OS=Desulfov... 163 4e-039
sp|Q4ZMA9|BIOF_PSEU2 8-amino-7-oxononanoate synthase OS=Pseudomo... 161 1e-038
sp|Q88A97|BIOF_PSESM 8-amino-7-oxononanoate synthase OS=Pseudomo... 161 2e-038
sp|Q48CS2|BIOF_PSE14 8-amino-7-oxononanoate synthase OS=Pseudomo... 160 3e-038
sp|O59682|LCB1_SCHPO Serine palmitoyltransferase 1 OS=Schizosacc... 155 1e-036
sp|Q3MHG1|SPTC1_BOVIN Serine palmitoyltransferase 1 OS=Bos tauru... 155 1e-036
sp|A4SPR6|BIOF_AERS4 8-amino-7-oxononanoate synthase OS=Aeromona... 153 3e-036
sp|O15269|SPTC1_HUMAN Serine palmitoyltransferase 1 OS=Homo sapi... 152 7e-036
sp|Q60HD1|SPTC1_MACFA Serine palmitoyltransferase 1 OS=Macaca fa... 152 7e-036
sp|Q5R9T5|SPTC1_PONAB Serine palmitoyltransferase 1 OS=Pongo abe... 151 2e-035
sp|A0KIC7|BIOF_AERHH 8-amino-7-oxononanoate synthase OS=Aeromona... 146 4e-034
>sp|O15270|SPTC2_HUMAN Serine palmitoyltransferase 2 OS=Homo sapiens GN=SPTLC2
PE=1 SV=1
Length = 562
Score = 416 bits (1069), Expect = 2e-115
Identities = 199/352 (56%), Positives = 267/352 (75%)
Frame = -3
Query: 1453 CTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIP 1274
C + L+++ CS+R + G H ELEE VA+++G AA+ GMGFATNS+ IP
Sbjct: 188 CQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIP 247
Query: 1273 VLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPW 1094
L+GKG LI+SD LNH S+V GAR SGATIR+F+HN LE++LK+ I GQPRT RPW
Sbjct: 248 ALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPW 307
Query: 1093 KKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDT 914
KKI+++VEGIYSMEG I +LPE++++ KKYKAY+YLDEAHSIGA+G TGRGV E G+D
Sbjct: 308 KKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDP 367
Query: 913 ADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVIL 734
D+D+MMGTFTKSFG+ GGYI G K+LI YL+ H + +YATS+S P +QII+S+K I+
Sbjct: 368 EDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIM 427
Query: 733 GEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECL 554
G+DG++ G + + ++ EN+ +FR L++MGF + G+ DSPV+P+MLY PAKI AF RE L
Sbjct: 428 GQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREML 487
Query: 553 RENVAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIKY 398
+ N+ VVVVGFPATP++ +RAR C+SA+H++E L ALK I + GDL +KY
Sbjct: 488 KRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKY 539
>sp|P97363|SPTC2_MOUSE Serine palmitoyltransferase 2 OS=Mus musculus GN=Sptlc2
PE=2 SV=2
Length = 560
Score = 415 bits (1065), Expect = 6e-115
Identities = 198/352 (56%), Positives = 267/352 (75%)
Frame = -3
Query: 1453 CTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIP 1274
C E LK++ CS+R + G H ELE+ VA+++G AA+ GMGFATNS+ IP
Sbjct: 186 CQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIP 245
Query: 1273 VLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPW 1094
L+GKG LI+SD LNH S+V GAR SGATIR+F+HN LE++LK+ I GQPRT RPW
Sbjct: 246 ALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPW 305
Query: 1093 KKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDT 914
KKI+++VEGIYSMEG I +LPE++++ KKYKAY+YLDEAHSIGA+G +GRGV + G+D
Sbjct: 306 KKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDP 365
Query: 913 ADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVIL 734
D+D+MMGTFTKSFG+ GGYI G K+LI YL+ H + +YATS+S P +QII+S+K I+
Sbjct: 366 EDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIM 425
Query: 733 GEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECL 554
G+DG++ G + + ++ EN+ +FR L++MGF + G+ DSPV+P+MLY PAKI AF RE L
Sbjct: 426 GQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREML 485
Query: 553 RENVAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIKY 398
+ N+ VVVVGFPATP++ +RAR C+SA+H++E L ALK I + GDL +KY
Sbjct: 486 KRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKY 537
>sp|O54694|SPTC2_CRIGR Serine palmitoyltransferase 2 OS=Cricetulus griseus
GN=SPTLC2 PE=2 SV=1
Length = 560
Score = 413 bits (1061), Expect = 2e-114
Identities = 199/352 (56%), Positives = 266/352 (75%)
Frame = -3
Query: 1453 CTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIP 1274
C E LK++ CS+R + G H ELE+ VA+++G AA+ GMGFATNS+ IP
Sbjct: 186 CQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIP 245
Query: 1273 VLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPW 1094
L+GKG LI+SD LNH S+V GAR SGATIR+F+HN LE++LK+ I GQPRT RPW
Sbjct: 246 ALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPW 305
Query: 1093 KKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDT 914
KKI+++VEGIYSMEG I +LPE++++ KKYKAY+YLDEAHSIGA+G +GRGV + G+D
Sbjct: 306 KKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDP 365
Query: 913 ADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVIL 734
D+D+MMGTFTKSFG+ GGYI G K LI YL+ H + +YATS+S P +QII+S+K I+
Sbjct: 366 EDVDVMMGTFTKSFGASGGYIGGKKALIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIM 425
Query: 733 GEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECL 554
G+DG++ G + + ++ EN+ +FR L++MGF + G+ DSPV+P+MLY PAKI AF RE L
Sbjct: 426 GQDGTSLGKECVQQLAENTKYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREML 485
Query: 553 RENVAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIKY 398
+ NV VVVVGFPATP++ +RAR C+SA+H++E L ALK I + GDL +KY
Sbjct: 486 KRNVGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKY 537
>sp|Q54EX5|SPTC2_DICDI Serine palmitoyltransferase 2 OS=Dictyostelium discoideum
GN=sptB PE=1 SV=1
Length = 490
Score = 403 bits (1033), Expect = 3e-111
Identities = 188/349 (53%), Positives = 263/349 (75%)
Frame = -3
Query: 1444 RVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLI 1265
+VI+S+ K+ T S+ + G + +LE A++VGK AIV MGFATNS +P LI
Sbjct: 133 KVIDSIYKYGVYTGSTSAEVGLSEPQRDLENLTARFVGKEDAIVFEMGFATNSGTLPALI 192
Query: 1264 GKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKI 1085
GKGGLIISDSLNH S+ G + +G ++VF+HN HLE V++E I +GQPRTHRPW I
Sbjct: 193 GKGGLIISDSLNHASLATGCKNTGCKVKVFRHNDSKHLEEVIRESIIQGQPRTHRPWTMI 252
Query: 1084 IVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADI 905
++++EGIYSMEGE+ LPEI+++ KKYK Y+Y+DEAHSIGA+GKTGRG+ + G+D +I
Sbjct: 253 LIIIEGIYSMEGEVANLPEILAIKKKYKCYLYIDEAHSIGALGKTGRGIVDYYGIDPKEI 312
Query: 904 DIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGED 725
DI+MGT+TKSFG+ GGY+A K LI +L+ + +YA S+S A Q + +++VI+GED
Sbjct: 313 DILMGTYTKSFGAIGGYVASDKSLIDHLRQSSFSQVYANSMSPVCAVQALEALRVIMGED 372
Query: 724 GSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLREN 545
G++ GA+KL ++ +NSN+FR ++++MGF +LG+ DSPV+P+ML+NPAK+ AFSR CL ++
Sbjct: 373 GTDTGAKKLKQLHDNSNYFREKIREMGFVILGNKDSPVIPLMLFNPAKLSAFSRLCLEKH 432
Query: 544 VAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIKY 398
+AVVVVG+PATPL R R CISASH+ EDL AL+ I + GDL +K+
Sbjct: 433 IAVVVVGYPATPLTEPRTRFCISASHTIEDLDWALRQIDEIGDLITLKF 481
>sp|Q9NUV7|SPTC3_HUMAN Serine palmitoyltransferase 3 OS=Homo sapiens GN=SPTLC3
PE=1 SV=3
Length = 552
Score = 394 bits (1011), Expect = 1e-108
Identities = 186/344 (54%), Positives = 260/344 (75%)
Frame = -3
Query: 1429 LKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGL 1250
L+ + S+R + GT H ELE+ VAK++ AA+V GMGFATNS+ IP L+GKG L
Sbjct: 188 LEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCL 247
Query: 1249 IISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKIIVVVE 1070
I+SD LNHTS+V GAR SGATIR+F+HN LE++L++ + GQPRT R WKKI+++VE
Sbjct: 248 ILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWKKILILVE 307
Query: 1069 GIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADIDIMMG 890
G+YSMEG I LP+I+++ KKYKAY+Y+DEAHSIGA+G TGRGV E G+D ++D++MG
Sbjct: 308 GVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMG 367
Query: 889 TFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGEDGSNRG 710
TFTKSFG+ GGYIAG KDL+ YL+ H + +YA+S+S P A+QII S+K+I+G DG+ +G
Sbjct: 368 TFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQG 427
Query: 709 AQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRENVAVVV 530
Q++ ++ +N+ +FR LQ+MGF + G+ ++ V+P++LY P K+ AF+R L + + VVV
Sbjct: 428 LQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVV 487
Query: 529 VGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIKY 398
VGFPATPL ARAR C+SA+H+RE L L+ + + GDL +KY
Sbjct: 488 VGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKY 531
>sp|Q8BG54|SPTC3_MOUSE Serine palmitoyltransferase 3 OS=Mus musculus GN=Sptlc3
PE=2 SV=1
Length = 563
Score = 368 bits (944), Expect = 6e-101
Identities = 178/351 (50%), Positives = 253/351 (72%)
Frame = -3
Query: 1444 RVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLI 1265
RV ++L+K+ S+R + GT +H ELE+ +A+++ A + GMGFATN++ IPV +
Sbjct: 183 RVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFV 242
Query: 1264 GKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKI 1085
GKG LI+SD NHTS++ G+R SGA IR F+HN +LE++L+E I GQP T R WKKI
Sbjct: 243 GKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGTGRAWKKI 302
Query: 1084 IVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADI 905
++VVEG+YSMEG I L +IV++ KKYKAY+Y+DEAHSIG G TGRGV EL G+D DI
Sbjct: 303 LIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDI 362
Query: 904 DIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGED 725
D+ MGTFTKSF GGYI G K+++ YL+ + YATS+S A Q+I S+K+ +G +
Sbjct: 363 DVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYE 422
Query: 724 GSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLREN 545
G+ G +++ +++EN +FR L++MGF + G++ SPV+P++LY PAK+ AFSR L++
Sbjct: 423 GNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKK 482
Query: 544 VAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIKYFP 392
++VVVVGFPAT L RAR +S++H+RE L L+V+ + GDL +KYFP
Sbjct: 483 ISVVVVGFPATSLPEGRARFSMSSAHTREMLDTVLEVVDELGDLLNVKYFP 533
>sp|Q09925|LCB2_SCHPO Serine palmitoyltransferase 2 OS=Schizosaccharomyces pombe
GN=lcb2 PE=2 SV=1
Length = 603
Score = 362 bits (928), Expect = 4e-099
Identities = 174/356 (48%), Positives = 246/356 (69%)
Frame = -3
Query: 1453 CTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIP 1274
C +V E+++K+ STCSS GT +H E+EE A +VGKPAA+V GF+TN+ +
Sbjct: 207 CATKVEEAMQKYGLSTCSSNAICGTYGLHKEVEELTANFVGKPAALVFSQGFSTNATVFS 266
Query: 1273 VLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPW 1094
L+ G LIISD LNHTSI GAR SGA IRV++HN LERVL+E I++GQPRTHRP+
Sbjct: 267 TLMCPGSLIISDELNHTSIRFGARLSGANIRVYKHNDMTDLERVLREVISQGQPRTHRPY 326
Query: 1093 KKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDT 914
KI+VV+EG+YSMEG C LP++V + +YK Y+++DEAHSIGAIG G G+C+ G+ T
Sbjct: 327 SKILVVIEGLYSMEGNFCDLPKVVELKNRYKFYLFIDEAHSIGAIGPRGGGICDYFGIST 386
Query: 913 ADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVIL 734
+DI+MGTFTKSFG+ GGYI+ + ++I L+ P ++YA S+S QI SS I+
Sbjct: 387 DHVDILMGTFTKSFGAAGGYISATPNIINKLRVTNPGYVYAESMSPAVLAQIKSSFLEIM 446
Query: 733 GEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECL 554
++ G +++ R+ NS + R L+++GF + G++DSPV+P++LYNP KI AFS E L
Sbjct: 447 DNSPTSAGLERIERLAFNSRYIRLGLKRLGFIIFGNDDSPVVPLLLYNPGKINAFSHEML 506
Query: 553 RENVAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIKYFPAA 386
+ +AVVVVG+PA PLL +R R C SASH++ D+ L+ + G+ +K+ A
Sbjct: 507 KRGIAVVVVGYPACPLLTSRVRFCFSASHNKADMDYFLRACDEVGEKLQLKFSTGA 562
>sp|P40970|LCB2_YEAST Serine palmitoyltransferase 2 OS=Saccharomyces cerevisiae
GN=LCB2 PE=1 SV=1
Length = 561
Score = 350 bits (897), Expect = 2e-095
Identities = 170/351 (48%), Positives = 241/351 (68%)
Frame = -3
Query: 1453 CTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIP 1274
CT +ES+ K+S + R GTT +H + E+ VA+++GK A+V MG+ TN+ +
Sbjct: 175 CTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFN 234
Query: 1273 VLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPW 1094
+ K L+ISD LNHTSI G R SGA +R F+H LE++++EQI GQP+T+RPW
Sbjct: 235 AFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTNRPW 294
Query: 1093 KKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDT 914
KKI++ EG++SMEG +C LP++V + KKYK Y+++DEAHSIGA+G TGRGVCE+ GVD
Sbjct: 295 KKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDP 354
Query: 913 ADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVIL 734
D+DI+MGTFTKSFG+ GGYIA + +I L+ Y+ S+ P Q ISS++ I
Sbjct: 355 KDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTIS 414
Query: 733 GEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECL 554
GE +G ++L RI NS + R LQ++GF V G DSPV+P++LY P+K+PAFSR L
Sbjct: 415 GEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMML 474
Query: 553 RENVAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIK 401
+ +AVVVV +PATPL+ +R R C+SAS ++ED+ L+ +S+ GD +K
Sbjct: 475 QRRIAVVVVAYPATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLK 525
>sp|P48241|LCB2_KLULA Serine palmitoyltransferase 2 OS=Kluyveromyces lactis
GN=LCB2 PE=3 SV=2
Length = 562
Score = 332 bits (849), Expect = 6e-090
Identities = 165/351 (47%), Positives = 231/351 (65%)
Frame = -3
Query: 1453 CTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIP 1274
CT +E+ K+ + R GTT +H E+ VA++VGK AI+ MG+ TN+
Sbjct: 174 CTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFN 233
Query: 1273 VLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPW 1094
+ L+ISDSLNHTSI G R SGA ++ F+HN LE++++EQI +GQ +THRPW
Sbjct: 234 SFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPW 293
Query: 1093 KKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDT 914
KKII+ VEG+YSMEG + LP++V + KKYK Y+++DEAHSIGA+G +GRGVC+ G+
Sbjct: 294 KKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPC 353
Query: 913 ADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVIL 734
+DIDIMMGT TKSFG+ GGYIA K +I + Y P QI SS+K I
Sbjct: 354 SDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTIT 413
Query: 733 GEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECL 554
G+ G ++L RI N+ + R LQ++GF V G DSPV+P++LY P+K+PAFSR L
Sbjct: 414 GDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIPMLLYAPSKMPAFSRMML 473
Query: 553 RENVAVVVVGFPATPLLLARARICISASHSREDLIKALKVISKAGDLTGIK 401
+ +AVVVV +PATPL+ +R R C+SA+ ++ED+ L+ I++ GD +K
Sbjct: 474 QRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQHINEVGDKLFLK 524
>sp|B8J3V0|BIOF_DESDA 8-amino-7-oxononanoate synthase OS=Desulfovibrio
desulfuricans (strain ATCC 27774 / DSM 6949) GN=bioF PE=3 SV=1
Length = 384
Score = 163 bits (411), Expect = 4e-039
Identities = 97/329 (29%), Positives = 166/329 (50%), Gaps = 18/329 (5%)
Frame = -3
Query: 1438 IESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGK 1259
+ +L+KF SR+ G + H +LE +A + G +A+ G+ N +I L K
Sbjct: 60 VRALEKFGTGAGGSRLVTGNMTPHMQLESALAAFKGSESALAFTSGYTANMGVISALCHK 119
Query: 1258 GGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKIIV 1079
+I SD+LNH SI++G R + V+ HN L E+I + +PR + +
Sbjct: 120 DTVIFSDALNHASIIDGCRLARGRTVVYAHNDMDD----LLEKIRQLRPR------QGFI 169
Query: 1078 VVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADIDI 899
+ +G++SM+G++ +LPE+ + + Y + +D+AH+ G +G TGRG E G+ D+ +
Sbjct: 170 ITDGVFSMDGDLARLPELAHIARSYGLTLMVDDAHATGVLGATGRGTLEHFGLSHEDVPV 229
Query: 898 MMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGEDGS 719
+ GT +K+ S GG++ GS+ L + L+ ++ T+ S + + I I G
Sbjct: 230 VTGTLSKAIPSEGGFVCGSEILCELLRNTARPFIFTTAPSPAAVAAATAGIGHIAAHPGL 289
Query: 718 NRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRENVA 539
R R+++N +F L + G V G SP++PIM K + L V
Sbjct: 290 VR------RLQDNVAYFTGSLAEQGMHVPG--QSPIIPIMAGEEEKAVRAAEALLALGVF 341
Query: 538 VVVVGFPATPLLLARARICISASHSREDL 452
+ +P P AR R+ + ASH+R+DL
Sbjct: 342 APCIRYPTVPRGQARLRLTVMASHTRDDL 370
>sp|Q4ZMA9|BIOF_PSEU2 8-amino-7-oxononanoate synthase OS=Pseudomonas syringae
pv. syringae (strain B728a) GN=bioF PE=3 SV=1
Length = 396
Score = 161 bits (407), Expect = 1e-038
Identities = 92/326 (28%), Positives = 171/326 (52%), Gaps = 18/326 (5%)
Frame = -3
Query: 1402 SSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHT 1223
+S + G ++ H ELEE +A+ G+P A++ G+ N + L+G+G ++ D LNH
Sbjct: 73 ASHLVIGHSAPHHELEEALAELTGRPRALLFSNGYMANLGAVTALVGQGDTVLEDRLNHA 132
Query: 1222 SIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKIIVVVEGIYSMEGEI 1043
S+++ SGA + HN + LE L++ + + +VV +G++SM+G+I
Sbjct: 133 SLLDAGLLSGARFSRYLHNDVSSLEARLEKSVGD-----------TLVVTDGVFSMDGDI 181
Query: 1042 CQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADIDIMMGTFTKSFGSC 863
LP + K A++ +D+AH G +G G G+ E G+ D+ +++GT KSFG+
Sbjct: 182 ADLPALARSAKAKGAWLMVDDAHGFGPLGANGAGIVEHFGLSMDDVPVLVGTLGKSFGTS 241
Query: 862 GGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGEDGSNRGAQKLARIRE 683
G ++AGS++LI+ L ++Y TS A + S++++ E + L R+ +
Sbjct: 242 GAFVAGSEELIETLIQFARPYIYTTSQPPALACATLKSLQLLRTEHWRR---EHLTRLIQ 298
Query: 682 NSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRENVAVVVVGFPATPLL 503
FR +++G +++ D+ +P+ PIM+ + + S+ + V + P P
Sbjct: 299 Q---FRRGAEQIGLQLM-DSFTPIQPIMIGDAGRALHLSQLLRERGLLVTAIRPPTVPAG 354
Query: 502 LARARICISASHSREDLIKALKVISK 425
AR R+ +SA+HS D+ L + +
Sbjct: 355 SARLRVTLSAAHSEADVQLLLNTLEQ 380
>sp|Q88A97|BIOF_PSESM 8-amino-7-oxononanoate synthase OS=Pseudomonas syringae
pv. tomato GN=bioF PE=3 SV=1
Length = 396
Score = 161 bits (406), Expect = 2e-038
Identities = 90/326 (27%), Positives = 166/326 (50%), Gaps = 18/326 (5%)
Frame = -3
Query: 1402 SSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHT 1223
+S + G ++ H ELEE +A+ G+P A++ G+ N + L+G+G ++ D LNH
Sbjct: 73 ASHLVIGHSTPHHELEEALAELTGRPRALLFSNGYMANLGAVTALVGQGDTVLEDRLNHA 132
Query: 1222 SIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKIIVVVEGIYSMEGEI 1043
S+++ SGA + HN L L++ + + +VV +G++SM+G+I
Sbjct: 133 SLLDAGLLSGARFSRYLHNDAGSLNARLEKAVGD-----------TLVVTDGVFSMDGDI 181
Query: 1042 CQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADIDIMMGTFTKSFGSC 863
LP + K A++ +D+AH G +G G G+ E G+ D+ +++GT KSFG+
Sbjct: 182 ADLPALAQAAKAKGAWLMVDDAHGFGPLGANGAGIVEHFGLSMEDVPVLVGTLGKSFGTS 241
Query: 862 GGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGEDGSNRGAQKLARIRE 683
G ++AGS++LI+ L ++Y TS A + S++++ E L
Sbjct: 242 GAFVAGSEELIETLIQFARPYIYTTSQPPALACATLKSLQLLRSEHWRREHLASLI---- 297
Query: 682 NSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRENVAVVVVGFPATPLL 503
FR +++G +++ D+ +P+ PIM+ + + S+ + V + P P
Sbjct: 298 --GQFRRGAEQLGLQLM-DSFTPIQPIMIGDAGRALRLSQLLRERGLLVTAIRPPTVPAG 354
Query: 502 LARARICISASHSREDLIKALKVISK 425
AR R+ +SA+HS D+ L+ + +
Sbjct: 355 SARLRVTLSAAHSEADVQLLLEALEQ 380
>sp|Q48CS2|BIOF_PSE14 8-amino-7-oxononanoate synthase OS=Pseudomonas syringae
pv. phaseolicola (strain 1448A / Race 6) GN=bioF PE=3 SV=1
Length = 396
Score = 160 bits (403), Expect = 3e-038
Identities = 90/326 (27%), Positives = 171/326 (52%), Gaps = 18/326 (5%)
Frame = -3
Query: 1402 SSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGLIISDSLNHT 1223
+S + G ++ H ELEE +A+ G+P A++ G+ N + L+G+G ++ D LNH
Sbjct: 73 ASHLVIGHSTPHHELEEALAELTGRPRALLFSNGYMANLGAVTALVGQGDTVLEDRLNHA 132
Query: 1222 SIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKIIVVVEGIYSMEGEI 1043
S+++ SGA + HN L L++ + + +VV +G++SM+G+I
Sbjct: 133 SLLDAGLLSGARFSRYLHNDVTSLASHLEKSVGD-----------TLVVTDGVFSMDGDI 181
Query: 1042 CQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADIDIMMGTFTKSFGSC 863
LP + K A++ +D+AH G +G G G+ E G+ D+ +++GT KSFG+
Sbjct: 182 ADLPALAQAAKAKGAWLMVDDAHGFGPLGANGAGIVEHFGLSMEDVPVLVGTLGKSFGTS 241
Query: 862 GGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGEDGSNRGAQKLARIRE 683
G ++AGS++LI+ L ++Y TS A + S++++ E + LA + +
Sbjct: 242 GAFVAGSEELIETLIQFARPYIYTTSQPPALACATLKSLQLLRTEHWRR---EHLASLIQ 298
Query: 682 NSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRENVAVVVVGFPATPLL 503
FR +++G +++ D+ +P+ PI++ + + S+ + V + P P
Sbjct: 299 Q---FRQGAEQIGLQLM-DSFTPIQPILIGDAGRALRLSQLLRERGLLVTAIRPPTVPAG 354
Query: 502 LARARICISASHSREDLIKALKVISK 425
AR R+ +SA+HS+ D+ L+ + +
Sbjct: 355 SARLRVTLSAAHSKADVQLLLEALEQ 380
>sp|O59682|LCB1_SCHPO Serine palmitoyltransferase 1 OS=Schizosaccharomyces pombe
GN=lcb1 PE=2 SV=1
Length = 509
Score = 155 bits (390), Expect = 1e-036
Identities = 105/371 (28%), Positives = 183/371 (49%), Gaps = 26/371 (7%)
Frame = -3
Query: 1462 DEYCTPRVIESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSV 1283
+++ T + +L++ C GT H LE+ +A ++G AIV F T S
Sbjct: 143 NKHITECAVATLRECGLGACGPPGFYGTQDKHLRLEKDIASFIGVERAIVYAQSFQTISS 202
Query: 1282 IIPVLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTH 1103
+IP +G +++ D + +I G + S TIR F+HN LER+L+E + + + +
Sbjct: 203 VIPAFSKRGDILVVDEACNFAIQKGIQISRTTIRYFKHNNMKDLERILQE-LEDDFVKHN 261
Query: 1102 RPWKKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLG 923
RP + ++ EGI G++ L +IV++ KKYK + LDE S G G+TG+G+ E G
Sbjct: 262 RPLTRRFIITEGISENYGDMVDLTKIVALKKKYKYRLILDETWSFGTCGRTGKGLTEHFG 321
Query: 922 VDTADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIK 743
V D++I++G+ T S GG+ AGS+ ++++ + A++Y+ ++ A +I
Sbjct: 322 VPPTDVEIIIGSLTTSLAGGGGFCAGSELMVEHQRLSGMAYIYSAALPASLAVAAYEAIS 381
Query: 742 VILGEDGSNRGAQKLARIRENSNFFRAELQK-MGFEVLGDNDSPVMPIMLYNPAKIPAFS 566
++ S G L +R S F A+L + FE D +SP++ + + I
Sbjct: 382 IL-----SRDGGSMLNDLRSKSALFHAKLSRNKFFETSSDIESPIIHLR-FKDKDISHDK 435
Query: 565 RECLRENVAVVVVGFPATPLLLARA---------------RICISASHSREDLIKALKVI 431
+ L E + + + A L+ARA RICIS HS E++ K +I
Sbjct: 436 QVFLLEEIVELCI---AEGFLIARAKRVESLERVKVQPSLRICISTGHSAEEIEKLALLI 492
Query: 430 SKAGDLTGIKY 398
+ ++ K+
Sbjct: 493 KEKTEIVFDKH 503
>sp|Q3MHG1|SPTC1_BOVIN Serine palmitoyltransferase 1 OS=Bos taurus GN=SPTLC1
PE=2 SV=1
Length = 473
Score = 155 bits (390), Expect = 1e-036
Identities = 105/352 (29%), Positives = 170/352 (48%), Gaps = 21/352 (5%)
Frame = -3
Query: 1438 IESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGK 1259
+ SLKK+ TC R GT VH +LE+ +AK++ AI+ GFAT + IP +
Sbjct: 122 LASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKR 181
Query: 1258 GGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQ--PRTHRPWKKI 1085
G ++ D +I G + S + I+VF HN LER+LKEQ E Q PR R ++
Sbjct: 182 GDIVFVDKAACFAIQKGLQASRSDIKVFNHNDMDDLERLLKEQEIEDQKNPRKARVTRRF 241
Query: 1084 IVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADI 905
I +VEG+Y G +C LPE+V + KYKA ++L+E+ S G +G+ GRGV E G+ DI
Sbjct: 242 I-IVEGLYMNTGTVCPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHFGISIDDI 300
Query: 904 DIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGED 725
D++ S S GG+ G +I + + + ++ S+ A I ++ ++
Sbjct: 301 DLISANMENSLASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENP 360
Query: 724 GSNRGAQKLARIRENSNFFRAELQKM-GFEVLGDNDSPVMPIMLYNPA--------KIPA 572
G A ++E LQ + G +V+G++ SP + + L +
Sbjct: 361 GI------FAVLKEKCKRIHKALQGIPGLKVVGESISPALHLQLEETTGCRERDVKLLQE 414
Query: 571 FSRECLRENVAVVVVGF---PATPLLLARARICISASHSREDLIKALKVISK 425
+C+ +A+ + L R+ ++ + EDL KA IS+
Sbjct: 415 IVTQCMDRGIALTQARYLEKEEKYLPPPSIRVVVTVEQTEEDLEKAASTISE 466
>sp|A4SPR6|BIOF_AERS4 8-amino-7-oxononanoate synthase OS=Aeromonas salmonicida
(strain A449) GN=bioF PE=3 SV=1
Length = 398
Score = 153 bits (386), Expect = 3e-036
Identities = 94/335 (28%), Positives = 166/335 (49%), Gaps = 20/335 (5%)
Frame = -3
Query: 1435 ESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKG 1256
E + + + +S + G + H +LEE +A ++G A ++ GF+ N ++ L+GK
Sbjct: 69 EGIDCYGTGSGASPLVTGYSRAHQQLEETLADWLGVEAVLLFNCGFSANQAVLKALLGKD 128
Query: 1255 GLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKIIVV 1076
L+ D LNH S+ ++ F HN LER L+ + ++V
Sbjct: 129 HLLWQDRLNHASLQEMGSQLPCKMKRFGHNDMTALERQLEP-------------NRGLIV 175
Query: 1075 VEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADIDIM 896
EG++SM+G+ PE+ + + ++ +D+AH +G +G GRG GV A + I
Sbjct: 176 SEGVFSMDGDQGPWPELARLAAQSGNWLMIDDAHGLGVLGPEGRGTLAAQGVAPASVHIQ 235
Query: 895 MGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGEDGSN 716
MGTF K+ G G ++ GS++L+ YL ++Y+T + T A + SI+++ D S
Sbjct: 236 MGTFGKALGVAGAFVGGSRELVDYLVNFARHYVYSTHMPTAQACAVSKSIELVRAADESR 295
Query: 715 RGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRENVAV 536
LAR+ FR +G++ LG +D+P+ P+++ + + V V
Sbjct: 296 ---AHLARLITR---FRQGTAALGWQ-LGASDTPIQPLLVGESSAALQLAARLRDRGVWV 348
Query: 535 VVVGFPATPLLLARARICISASHSREDLIKALKVI 431
+ P P+ AR RI +SA+H +D+ + LK +
Sbjct: 349 SAIRPPTVPVGTARLRITLSAAHREQDVDRLLKAL 383
>sp|O15269|SPTC1_HUMAN Serine palmitoyltransferase 1 OS=Homo sapiens GN=SPTLC1
PE=1 SV=1
Length = 473
Score = 152 bits (383), Expect = 7e-036
Identities = 98/291 (33%), Positives = 153/291 (52%), Gaps = 14/291 (4%)
Frame = -3
Query: 1447 PRV----IESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVI 1280
PRV + SLKK+ TC R GT VH +LE+ +AK++ AI+ GFAT +
Sbjct: 115 PRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASA 174
Query: 1279 IPVLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQ--PRT 1106
IP +G ++ D +I G + S + I++F+HN A LER+LKEQ E Q PR
Sbjct: 175 IPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRK 234
Query: 1105 HRPWKKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELL 926
R ++ I VVEG+Y G IC LPE+V + KYKA ++L+E+ S G +G+ GRGV E
Sbjct: 235 ARVTRRFI-VVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHY 293
Query: 925 GVDTADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSI 746
G++ DID++ + S GG+ G +I + + + ++ S+ A I ++
Sbjct: 294 GINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEAL 353
Query: 745 KVILGEDGSNRGAQKLARIRENSNFFRAELQKM-GFEVLGDNDSPVMPIML 596
++ G A ++E LQ + G +V+G++ SP + L
Sbjct: 354 NIMEENPGI------FAVLKEKCGQIHKALQGISGLKVVGESLSPAFHLQL 398
>sp|Q60HD1|SPTC1_MACFA Serine palmitoyltransferase 1 OS=Macaca fascicularis
GN=SPTLC1 PE=2 SV=1
Length = 473
Score = 152 bits (383), Expect = 7e-036
Identities = 98/291 (33%), Positives = 153/291 (52%), Gaps = 14/291 (4%)
Frame = -3
Query: 1447 PRV----IESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVI 1280
PRV + SLKK+ TC R GT VH +LE+ +AK++ AI+ GFAT +
Sbjct: 115 PRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASA 174
Query: 1279 IPVLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQ--PRT 1106
IP +G ++ D +I G + S + I++F+HN A LER+LKEQ E Q PR
Sbjct: 175 IPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRK 234
Query: 1105 HRPWKKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELL 926
R ++ I VVEG+Y G IC LPE+V + KYKA ++L+E+ S G +G+ GRGV E
Sbjct: 235 ARVTRRFI-VVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHY 293
Query: 925 GVDTADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSI 746
G++ DID++ + S GG+ G +I + + + ++ S+ A I ++
Sbjct: 294 GINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEAL 353
Query: 745 KVILGEDGSNRGAQKLARIRENSNFFRAELQKM-GFEVLGDNDSPVMPIML 596
++ G A ++E LQ + G +V+G++ SP + L
Sbjct: 354 NIMEENPGI------FAVLKEKCRQIHKALQGISGLKVVGESLSPAFHLQL 398
>sp|Q5R9T5|SPTC1_PONAB Serine palmitoyltransferase 1 OS=Pongo abelii GN=SPTLC1
PE=2 SV=1
Length = 473
Score = 151 bits (380), Expect = 2e-035
Identities = 98/291 (33%), Positives = 152/291 (52%), Gaps = 14/291 (4%)
Frame = -3
Query: 1447 PRV----IESLKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVI 1280
PRV + SLKK+ TC R GT VH +LE+ +AK++ AI+ GFAT +
Sbjct: 115 PRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASA 174
Query: 1279 IPVLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQ--PRT 1106
IP +G ++ D +I G + S + I++F+HN A LER+LKEQ E Q PR
Sbjct: 175 IPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRK 234
Query: 1105 HRPWKKIIVVVEGIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELL 926
R ++ I VVEG+Y G IC LPE+V + KYKA ++L+E+ S G +G+ GRGV E
Sbjct: 235 ARVTRRFI-VVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHY 293
Query: 925 GVDTADIDIMMGTFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSI 746
G++ DID++ + S GG+ G +I + + + ++ S+ A I ++
Sbjct: 294 GINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEAL 353
Query: 745 KVILGEDGSNRGAQKLARIRENSNFFRAELQKM-GFEVLGDNDSPVMPIML 596
++ G A ++E LQ + G +V+G+ SP + L
Sbjct: 354 NIMEENPGI------FAVLKEKCRQIHKALQGISGLKVVGEPLSPAFHLQL 398
>sp|A0KIC7|BIOF_AERHH 8-amino-7-oxononanoate synthase OS=Aeromonas hydrophila
subsp. hydrophila (strain ATCC 7966 / NCIB 9240) GN=bioF PE=3 SV=1
Length = 398
Score = 146 bits (368), Expect = 4e-034
Identities = 87/333 (26%), Positives = 162/333 (48%), Gaps = 20/333 (6%)
Frame = -3
Query: 1429 LKKFSPSTCSSRVDAGTTSVHAELEECVAKYVGKPAAIVTGMGFATNSVIIPVLIGKGGL 1250
+ ++ +S + G + H +LEE +A ++G A ++ GF+ N ++ L+GK L
Sbjct: 71 IDRYGAGAGASPLVTGYSRAHQQLEETLADWLGVEAVLLFNCGFSANQAVLKALLGKDHL 130
Query: 1249 IISDSLNHTSIVNGARGSGATIRVFQHNTPAHLERVLKEQIAEGQPRTHRPWKKIIVVVE 1070
+ D LNH S+ ++ F HN LER L+ + ++V E
Sbjct: 131 LWQDKLNHASLQEMGSQLPCKMKRFGHNDMTALERQLEP-------------NRGLIVSE 177
Query: 1069 GIYSMEGEICQLPEIVSVCKKYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTADIDIMMG 890
G++SM+G+ E+ ++ + ++ +D+AH +G +G GRG GV A + I MG
Sbjct: 178 GVFSMDGDQGSWRELAALAAQSGNWLMIDDAHGLGVLGSEGRGTLAAQGVAPASVHIQMG 237
Query: 889 TFTKSFGSCGGYIAGSKDLIQYLKYHCPAHLYATSISTPSAQQIISSIKVILGEDGSNRG 710
TF K+ G G ++ GS++L+ YL ++Y+T + A + SI+++ D
Sbjct: 238 TFGKALGVAGAFVGGSRELVDYLVNFARHYVYSTHMPAAQACAVSQSIELVRAAD----- 292
Query: 709 AQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRENVAVVV 530
+ A + + FR Q +G++ LG +D+P+ P+++ + V
Sbjct: 293 -EARAHLGQLITRFRQGAQALGWQ-LGASDTPIQPLLVGESGAALQLAERLRECGVWAGA 350
Query: 529 VGFPATPLLLARARICISASHSREDLIKALKVI 431
+ P P+ AR RI +SA+H +D+ + L+ +
Sbjct: 351 IRPPTVPVGTARLRITLSAAHREQDVDRLLEAL 383
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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