BLASTX 7.6.2
Query= UN21579 /QuerySize=1492
(1491 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O23653|AK2_ARATH Aspartokinase 2, chloroplastic OS=Arabidopsi... 815 2e-235
sp|Q9S702|AK3_ARATH Aspartokinase 3, chloroplastic OS=Arabidopsi... 748 4e-215
sp|Q9LYU8|AK1_ARATH Aspartokinase 1, chloroplastic OS=Arabidopsi... 681 6e-195
sp|Q57991|AK_METJA Probable aspartokinase OS=Methanocaldococcus ... 234 2e-060
sp|P08660|AK3_ECOLI Lysine-sensitive aspartokinase 3 OS=Escheric... 195 1e-048
sp|P00561|AK1H_ECOLI Bifunctional aspartokinase/homoserine dehyd... 167 3e-040
sp|P49080|AKH2_MAIZE Bifunctional aspartokinase/homoserine dehyd... 167 3e-040
sp|Q89AR4|AKH_BUCBP Bifunctional aspartokinase/homoserine dehydr... 166 5e-040
sp|P49079|AKH1_MAIZE Bifunctional aspartokinase/homoserine dehyd... 162 9e-039
sp|O81852|AKH2_ARATH Bifunctional aspartokinase/homoserine dehyd... 159 6e-038
sp|Q9SA18|AKH1_ARATH Bifunctional aspartokinase/homoserine dehyd... 159 8e-038
sp|P44505|AKH_HAEIN Bifunctional aspartokinase/homoserine dehydr... 158 2e-037
sp|P27725|AK1H_SERMA Bifunctional aspartokinase/homoserine dehyd... 156 5e-037
sp|Q8RQN1|AK_COREF Aspartokinase OS=Corynebacterium efficiens GN... 154 2e-036
sp|P26512|AK_CORGL Aspartokinase OS=Corynebacterium glutamicum G... 151 2e-035
sp|P41398|AK_CORFL Aspartokinase OS=Corynebacterium flavum GN=ly... 150 3e-035
sp|P37142|AKH_DAUCA Bifunctional aspartokinase/homoserine dehydr... 148 1e-034
sp|P0A4Z9|AK_MYCBO Aspartokinase OS=Mycobacterium bovis GN=ask P... 146 5e-034
sp|P0A4Z8|AK_MYCTU Aspartokinase OS=Mycobacterium tuberculosis G... 146 5e-034
sp|Q8K9U9|AKH_BUCAP Bifunctional aspartokinase/homoserine dehydr... 145 1e-033
>sp|O23653|AK2_ARATH Aspartokinase 2, chloroplastic OS=Arabidopsis thaliana
GN=AK2 PE=1 SV=2
Length = 544
Score = 815 bits (2104), Expect = 2e-235
Identities = 417/437 (95%), Positives = 428/437 (97%)
Frame = +3
Query: 36 LLPFPEERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGV 215
+L FP+ERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGV
Sbjct: 106 ILSFPDERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGV 165
Query: 216 ETTVIAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYD 395
ETTVI +HLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYD
Sbjct: 166 ETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYD 225
Query: 396 AFEIGFITTDDFTNADILEATYPAVSKTLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGR 575
AFEIGFITTDDFTNADILEATYPAVSKTL+ +WSK+ AVPVVTG+LGKGWRSCAITTLGR
Sbjct: 226 AFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKENAVPVVTGYLGKGWRSCAITTLGR 285
Query: 576 GGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQV 755
GGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIY GAQSVP LTFDEAAELAYFGAQV
Sbjct: 286 GGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYPGAQSVPYLTFDEAAELAYFGAQV 345
Query: 756 LHPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTR 935
LHPLSMRPARDGDIPVRVKNSYNP APGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTR
Sbjct: 346 LHPLSMRPARDGDIPVRVKNSYNPTAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTR 405
Query: 936 MLGQYGFLAKVFTTFEDLGISVDVVATSEVSISLTLDPAKLWGRELVQRANELDHVVEEL 1115
MLGQYGFLAKVFTTFEDLGISVDVVATSEVSISLTLDPAKLWGREL+QR NELD++VEEL
Sbjct: 406 MLGQYGFLAKVFTTFEDLGISVDVVATSEVSISLTLDPAKLWGRELIQRVNELDNLVEEL 465
Query: 1116 EKIAVVKLLQRRSIISLIGNVQKSSLILEKVFKVLRSNGVNVQMISQGASKVNISLIVND 1295
EKIAVVKLLQRRSIISLIGNVQKSSLILEKVF+V RSNGVNVQMISQGASKVNISLIVND
Sbjct: 466 EKIAVVKLLQRRSIISLIGNVQKSSLILEKVFQVFRSNGVNVQMISQGASKVNISLIVND 525
Query: 1296 EEAEQCVRALHSAFFET 1346
EEAEQCVRALHSAFFET
Sbjct: 526 EEAEQCVRALHSAFFET 542
>sp|Q9S702|AK3_ARATH Aspartokinase 3, chloroplastic OS=Arabidopsis thaliana
GN=AK3 PE=1 SV=1
Length = 559
Score = 748 bits (1929), Expect = 4e-215
Identities = 380/439 (86%), Positives = 411/439 (93%), Gaps = 2/439 (0%)
Frame = +3
Query: 36 LLPFPEERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGV 215
+L FP+E+PV+VLSAM KTTNKLL AGEKAV CGVTNV++IEELS+IKELH+RTAHELGV
Sbjct: 107 ILSFPDEKPVVVLSAMAKTTNKLLMAGEKAVCCGVTNVDTIEELSYIKELHIRTAHELGV 166
Query: 216 ETTVIAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYD 395
ET VIA+HLEGL QLLKG++MMKELTLR+RDYLVSFGECMSTRLF+AYLNKIGHKARQYD
Sbjct: 167 ETAVIAEHLEGLEQLLKGVAMMKELTLRSRDYLVSFGECMSTRLFAAYLNKIGHKARQYD 226
Query: 396 AFEIGFITTDDFTNADILEATYPAVSKTLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGR 575
AFEIG ITTDDFTNADILEATYPAVSK LL +WSK+ A+PVVTGFLGKGWRSCA+TTLGR
Sbjct: 227 AFEIGIITTDDFTNADILEATYPAVSKKLLGDWSKENALPVVTGFLGKGWRSCAVTTLGR 286
Query: 576 GGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQV 755
GGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIY GAQ VP LTFDEAAELAYFGAQV
Sbjct: 287 GGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYCGAQPVPHLTFDEAAELAYFGAQV 346
Query: 756 LHPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTR 935
LHPLSMRPAR+G+IPVRVKNSYNP APGTVITRSRDMSKAVLTSIVLKRNVTMLDI STR
Sbjct: 347 LHPLSMRPAREGNIPVRVKNSYNPTAPGTVITRSRDMSKAVLTSIVLKRNVTMLDITSTR 406
Query: 936 MLGQYGFLAKVFTTFEDLGISVDVVATSEVSISLTLDPAKLWGRELVQRANELDHVVEEL 1115
MLGQYGFLAKVF+TFE LGISVDVVATSEVSISLTLDP+K REL+Q +ELD VVEEL
Sbjct: 407 MLGQYGFLAKVFSTFEKLGISVDVVATSEVSISLTLDPSKFCSRELIQ--HELDQVVEEL 464
Query: 1116 EKIAVVKLLQRRSIISLIGNVQKSSLILEKVFKVLRSNGVNVQMISQGASKVNISLIVND 1295
EKIAVV LL+ RSIISLIGNVQ+SS ILEK F+VLR+NG+NVQMISQGASKVNISLIVND
Sbjct: 465 EKIAVVNLLRHRSIISLIGNVQRSSFILEKGFRVLRTNGINVQMISQGASKVNISLIVND 524
Query: 1296 EEAEQCVRALHSAFFETSS 1352
+EAE CV+ALHSAFFET +
Sbjct: 525 DEAEHCVKALHSAFFETDT 543
>sp|Q9LYU8|AK1_ARATH Aspartokinase 1, chloroplastic OS=Arabidopsis thaliana
GN=AK1 PE=1 SV=1
Length = 569
Score = 681 bits (1755), Expect = 6e-195
Identities = 347/437 (79%), Positives = 388/437 (88%), Gaps = 2/437 (0%)
Frame = +3
Query: 36 LLPFPEERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGV 215
+L FPEE PVIVLSAMGKTTN LL AGEKAV+CGV+N IEELS IKELH+RT EL +
Sbjct: 110 ILTFPEESPVIVLSAMGKTTNNLLLAGEKAVSCGVSNASEIEELSIIKELHIRTVKELNI 169
Query: 216 ETTVIAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYD 395
+ +VI +LE L QLLKGI+MMKELTLRTRDYLVSFGEC+STR+F+AYLN IG KARQYD
Sbjct: 170 DPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGECLSTRIFAAYLNTIGVKARQYD 229
Query: 396 AFEIGFITTDDFTNADILEATYPAVSKTLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGR 575
AFEIGFITTDDFTN DILEATYPAV+K L ++W D AVP+VTGFLGKGW++ A+TTLGR
Sbjct: 230 AFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAVPIVTGFLGKGWKTGAVTTLGR 289
Query: 576 GGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQV 755
GGSDLTATTIGKALGL+EIQVWKDVDGVLTCDP IY A VP LTFDEAAELAYFGAQV
Sbjct: 290 GGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTIYKRATPVPYLTFDEAAELAYFGAQV 349
Query: 756 LHPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTR 935
LHP SMRPAR+G+IPVRVKNSYNP APGT+IT++RDM+K++LTSIVLKRNVTMLDIASTR
Sbjct: 350 LHPQSMRPAREGEIPVRVKNSYNPKAPGTIITKTRDMTKSILTSIVLKRNVTMLDIASTR 409
Query: 936 MLGQYGFLAKVFTTFEDLGISVDVVATSEVSISLTLDPAKLWGRELVQRANELDHVVEEL 1115
MLGQ GFLAKVF+ FE+LGISVDVVATSEVSISLTLDP+KLW REL+Q+ ELDHVVEEL
Sbjct: 410 MLGQVGFLAKVFSIFEELGISVDVVATSEVSISLTLDPSKLWSRELIQQ--ELDHVVEEL 467
Query: 1116 EKIAVVKLLQRRSIISLIGNVQKSSLILEKVFKVLRSNGVNVQMISQGASKVNISLIVND 1295
EKIAVV LL+ R+IISLIGNVQ SSLILE+ F VL + GVNVQMISQGASKVNIS IVN+
Sbjct: 468 EKIAVVNLLKGRAIISLIGNVQHSSLILERAFHVLYTKGVNVQMISQGASKVNISFIVNE 527
Query: 1296 EEAEQCVRALHSAFFET 1346
EAE CV+ALH +FFE+
Sbjct: 528 AEAEGCVQALHKSFFES 544
>sp|Q57991|AK_METJA Probable aspartokinase OS=Methanocaldococcus jannaschii
GN=MJ0571 PE=1 SV=1
Length = 473
Score = 234 bits (595), Expect = 2e-060
Identities = 147/445 (33%), Positives = 255/445 (57%), Gaps = 23/445 (5%)
Frame = +3
Query: 63 VIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEE-LSFIKELHLRT------AHELGVET 221
V+V+SAM + TN L++ ++A+ V ++ + + + FI+E H + + E+ E
Sbjct: 36 VVVVSAMSEVTNALVEISQQAL--DVRDIAKVGDFIKFIREKHYKAIEEAIKSEEIKEEV 93
Query: 222 -TVIAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDA 398
+I +E L ++L G++ + ELT ++RDY++SFGE +S+ + S + +G K+ +
Sbjct: 94 KKIIDSRIEELEKVLIGVAYLGELTPKSRDYILSFGERLSSPILSGAIRDLGEKSIALEG 153
Query: 399 FEIGFITTDDFTNADILEATYPAVSKTLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGRG 578
E G IT ++F +A + LL K+ +PVVTGF+G ITTLGRG
Sbjct: 154 GEAGIITDNNFGSARVKRLEVKERLLPLL----KEGIIPVVTGFIGT-TEEGYITTLGRG 208
Query: 579 GSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQVL 758
GSD +A IG L I++W DV GV T DP + A+ +P L++ EA ELAYFGA+VL
Sbjct: 209 GSDYSAALIGYGLDADIIEIWTDVSGVYTTDPRLVPTARRIPKLSYIEAMELAYFGAKVL 268
Query: 759 HPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTRM 938
HP ++ PA + IP+ VKN++ P + GT+IT +MS +++ +I +NV +++I M
Sbjct: 269 HPRTIEPAMEKGIPILVKNTFEPESEGTLITNDMEMSDSIVKAISTIKNVALINIFGAGM 328
Query: 939 LGQYGFLAKVFTTFEDLGISVDVVA--TSEVSISLTLDPAKLWGRELVQRANELDHVVEE 1112
+G G A++F + ++V +++ +SE +ISL + + + L E ++
Sbjct: 329 VGVSGTAARIFKALGEEEVNVILISQGSSETNISLVVSEEDV-DKALKALKREFGDFGKK 387
Query: 1113 L----EKIAVVKLLQRRSIISLIG-NVQKSSLILEKVFKVLRSNGVNVQMISQGASKVNI 1277
I V + + +IS++G ++ + I K+F + +G N++MI+QG+S+VNI
Sbjct: 388 SFLNNNLIRDVSVDKDVCVISVVGAGMRGAKGIAGKIFTAVSESGANIKMIAQGSSEVNI 447
Query: 1278 SLIVNDEEAEQCVRALHSAFFETSS 1352
S ++++++ CVR LH F E ++
Sbjct: 448 SFVIDEKDLLNCVRKLHEKFIEKTN 472
>sp|P08660|AK3_ECOLI Lysine-sensitive aspartokinase 3 OS=Escherichia coli
(strain K12) GN=lysC PE=1 SV=2
Length = 449
Score = 195 bits (494), Expect = 1e-048
Identities = 146/430 (33%), Positives = 224/430 (52%), Gaps = 28/430 (6%)
Frame = +3
Query: 63 VIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGVETTVIAQHL 242
++VLSA TN L+ E G+ E E+L I+ + L +
Sbjct: 35 LVVLSASAGITNLLVALAE-----GLEPGERFEKLDAIRNIQFAILERLRYPNVI----R 85
Query: 243 EGLHQLLKGISMMKELTL-----RTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEI 407
E + +LL+ I+++ E D LVS GE MST LF L + +A+ +D ++
Sbjct: 86 EEIERLLENITVLAEAAALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKV 145
Query: 408 GFITTDDFTNA--DILEATYPAVSKTLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGRGG 581
T D F A DI A + L ++ + + GF+G + TTLGRGG
Sbjct: 146 -MRTNDRFGRAEPDIAALAELAALQLLPR---LNEGLVITQGFIGSENKG-RTTTLGRGG 200
Query: 582 SDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQVLH 761
SD TA + +AL + +W DV G+ T DP + S A+ + + F EAAE+A FGA+VLH
Sbjct: 201 SDYTAALLAEALHASRVDIWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLH 260
Query: 762 PLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTRML 941
P ++ PA DIPV V +S +P A GT++ + + + ++ L+RN T+L + S ML
Sbjct: 261 PATLLPAVRSDIPVFVGSSKDPRAGGTLVCNKTE-NPPLFRALALRRNQTLLTLHSLNML 319
Query: 942 GQYGFLAKVFTTFEDLGISVDVVATSEVSISLTLDPAKLWGRELVQRANELDHVVEELEK 1121
GFLA+VF ISVD++ TSEVS++LTLD G ++ EL
Sbjct: 320 HSRGFLAEVFGILARHNISVDLITTSEVSVALTLDTT---GSTSTGDTLLTQSLLMELSA 376
Query: 1122 IAVVKLLQRRSIISLIGN-VQKSSLILEKVFKVLRSNGVNVQMISQGASKVNISLIVNDE 1298
+ V++ + ++++LIGN + K+ + ++VF VL N++MI GAS N+ +V E
Sbjct: 377 LCRVEVEEGLALVALIGNDLSKACGVGKEVFGVLEP--FNIRMICYGASSHNLCFLVPGE 434
Query: 1299 EAEQCVRALH 1328
+AEQ V+ LH
Sbjct: 435 DAEQVVQKLH 444
>sp|P00561|AK1H_ECOLI Bifunctional aspartokinase/homoserine dehydrogenase 1
OS=Escherichia coli (strain K12) GN=thrA PE=1 SV=2
Length = 820
Score = 167 bits (421), Expect = 3e-040
Identities = 134/438 (30%), Positives = 210/438 (47%), Gaps = 23/438 (5%)
Frame = +3
Query: 69 VLSAMGKTTNKLLKAGEKAVT--CGVTNVESIEELSFIKELHLRTAHELGVE----TTVI 230
VLSA K TN L+ EK ++ + N+ E + F + L A + G T +
Sbjct: 36 VLSAPAKITNHLVAMIEKTISGQDALPNISDAERI-FAELLTGLAAAQPGFPLAQLKTFV 94
Query: 231 AQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEIG 410
Q + +L GIS++ + L+ GE MS + + L GH D E
Sbjct: 95 DQEFAQIKHVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVE-K 153
Query: 411 FITTDDF--TNADILEATYPAVSKTLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGRGGS 584
+ + + DI E+T + + D V ++ GF G + LGR GS
Sbjct: 154 LLAVGHYLESTVDIAESTRRIAASRI----PADHMV-LMAGFTA-GNEKGELVVLGRNGS 207
Query: 585 DLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQVLHP 764
D +A + L ++W DVDGV TCDP A+ + +++ EA EL+YFGA+VLHP
Sbjct: 208 DYSAAVLAACLRADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHP 267
Query: 765 LSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTRMLG 944
++ P IP +KN+ NP APGT+I SRD + + I N+ M ++ M G
Sbjct: 268 RTITPIAQFQIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKG 327
Query: 945 QYGFLAKVFTTFEDLGISVDVV--ATSEVSISLTLDPAK-LWGRELVQRANELDHVVEEL 1115
G A+VF ISV ++ ++SE SIS + + + +Q L+ L
Sbjct: 328 MVGMAARVFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLL 387
Query: 1116 EKIAVVKLLQRRSIISLIGNVQKSSL-ILEKVFKVLRSNGVNVQMISQGASKVNISLIVN 1292
E +AV +R +IIS++G+ ++ I K F L +N+ I+QG+S+ +IS++VN
Sbjct: 388 EPLAVT---ERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVN 444
Query: 1293 DEEAEQCVRALHSAFFET 1346
+++A VR H F T
Sbjct: 445 NDDATTGVRVTHQMLFNT 462
>sp|P49080|AKH2_MAIZE Bifunctional aspartokinase/homoserine dehydrogenase 2,
chloroplastic OS=Zea mays GN=AKHSDH2 PE=2 SV=1
Length = 917
Score = 167 bits (421), Expect = 3e-040
Identities = 126/447 (28%), Positives = 226/447 (50%), Gaps = 31/447 (6%)
Frame = +3
Query: 54 ERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGVETTVIA 233
ER +I++SAM K T+ + +KA + + ++ E + E H+ A +L ++ +A
Sbjct: 120 ERKLIIVSAMSKVTDMMYNLVQKAQSRDDSYAIALAE---VFEKHMTAAKDL-LDGEDLA 175
Query: 234 QHLEGLHQ-------LLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQY 392
+ L LH +L+ I + T D++V GE S ++ S + K G
Sbjct: 176 RFLSQLHSDVSNLRAMLRAIYIAGHATESFSDFVVGHGELWSAQMLSYAIKKSGAPCSWM 235
Query: 393 DAFEIGFITTDDFTNADILEATYPAVSKTLLNNWSKDKA-VPVVTGFLGKGWRSCAITTL 569
D E+ +T D Y K L +S+ A + V TGF+ + TTL
Sbjct: 236 DTREVLVVTPSGCNQVD---PDYLECEKRLQKWFSRQPAEIIVATGFIASTAGNIP-TTL 291
Query: 570 GRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGA 749
R GSD +A +G + R++ +W DVDGV + DP S A + L++ EA E++YFGA
Sbjct: 292 KRDGSDFSAAIVGSLVRARQVTIWTDVDGVFSADPRKVSEAVILSTLSYQEAWEMSYFGA 351
Query: 750 QVLHPLSMRPARDGDIPVRVKNSYNPNAPGTVITR-----SRDMSKAVLTSIVLKRNVTM 914
VLHP ++ P +IP+ ++N +N +APGT+I + + D+ A + S N+ +
Sbjct: 352 NVLHPRTIIPVMKDNIPIVIRNMFNLSAPGTMICKQPANENGDLD-ACVKSFATVDNLAL 410
Query: 915 LDIASTRMLGQYGFLAKVFTTFEDLGISVDVV--ATSEVSISLTLDPAKLWGRELVQRAN 1088
+++ T M G G + +F+ +D+G +V ++ A+SE S+ + ++ V A
Sbjct: 411 VNVEGTGMAGVPGTASAIFSAVKDVGANVIMISQASSEHSVCFAVPEKEV----AVVSAE 466
Query: 1089 ELDHVVEELE--KIAVVKLLQRRSIISLIG-NVQKSSLILEKVFKVLRSNGVNVQMISQG 1259
D E L +++ V+++ SI++ +G + + + +F L +NV+ I+QG
Sbjct: 467 LHDRFREALAAGRLSKVEVINGCSILAAVGLRMASTPGVSAILFDALAKANINVRAIAQG 526
Query: 1260 ASKVNISLIVNDEEAEQCVRALHSAFF 1340
S+ NI++++ ++ + +RA HS FF
Sbjct: 527 CSEYNITVVLKQQDCVRALRAAHSRFF 553
>sp|Q89AR4|AKH_BUCBP Bifunctional aspartokinase/homoserine dehydrogenase
OS=Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) GN=thrA
PE=3 SV=1
Length = 816
Score = 166 bits (419), Expect = 5e-040
Identities = 128/448 (28%), Positives = 226/448 (50%), Gaps = 24/448 (5%)
Frame = +3
Query: 54 ERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHEL-GVETTVI 230
E+ IVLSA G TTN L E A+ + N I + I++ L+ +++ VE ++
Sbjct: 31 EQIAIVLSAPGNTTNLL----EIAINQTINNKNIIPIVQKIEKNFLKLINDIYQVEQKLL 86
Query: 231 AQHLEG--------LHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKAR 386
+ ++ L LL+GI+++++ + R ++S GE +S + ++ L G+
Sbjct: 87 YEKIKNNIENKLLELKNLLQGINLLRQCPDKIRAKIISSGEYLSISIMNSILISRGYNTT 146
Query: 387 QYDAFEIGFITTDDFTNADILEATYPAVSKTLLNNWSKDKAVPVVTGFLGKGWRSCAITT 566
D + D + NA + +SK + + K ++ G + + T
Sbjct: 147 IIDPVKKLLTKEDTYLNATV----NIKISKFRILSMKIPKHHIILMPGFTAGNKQGELVT 202
Query: 567 LGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFG 746
LGR GSD +AT + L ++W DV+GV TCDP + S A+ + L++ EA EL+Y G
Sbjct: 203 LGRNGSDYSATILSVCLNSTMCEIWTDVNGVYTCDPKLVSDAKLLTSLSYREAIELSYLG 262
Query: 747 AQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIA 926
A++LHP ++ P + IP +KN++NP++ GT I+ + +K ++T + NV M I+
Sbjct: 263 AKILHPNTIYPIQKFKIPCTIKNTHNPSSIGTKISCNHVKNKNLITGVTYLENVHMFSIS 322
Query: 927 STRMLGQYGFLAKVFT--TFEDLGISVDVVATSEVSISL-TLDPAKLWGRELVQRANELD 1097
+ K+F+ + + I + + +S+ +IS L ++ +A L+
Sbjct: 323 CLYSKNIETIIPKIFSCMSLSKIWIILTIQTSSQNTISFCILKTMTNTALHVLHKALYLE 382
Query: 1098 HVVEELEKIAVVKLLQRRSIISLIGNVQKSSLILEKVFKVLRSNGVNVQMISQGASKVNI 1277
+ L+ I V K L S+IS ++ ++ I EKVF +L+ +N IS+GASK +I
Sbjct: 383 LKHKLLKPIKVEKKLTLISVIS--SDILNNTKITEKVFSILKHVNINTLAISKGASKNSI 440
Query: 1278 SLIVNDEEAEQCVRALHSAFFETSS*CT 1361
S++V ++ VRALH F + CT
Sbjct: 441 SIVVKHDDGILGVRALHKGIFNKN--CT 466
>sp|P49079|AKH1_MAIZE Bifunctional aspartokinase/homoserine dehydrogenase 1,
chloroplastic OS=Zea mays GN=AKHSDH1 PE=2 SV=1
Length = 920
Score = 162 bits (408), Expect = 9e-039
Identities = 126/450 (28%), Positives = 225/450 (50%), Gaps = 33/450 (7%)
Frame = +3
Query: 48 PEERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGVETTV 227
P ER ++V+SAM K T+ + KA + + + ++E + + H+ TA +L +
Sbjct: 121 PSERKLVVVSAMSKVTDMMYNLVNKAQSRDDSYIAVLDE---VFDKHMTTAKDL-LAGED 176
Query: 228 IAQHLEGLH-------QLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKAR 386
+A+ L LH +L+ I + T D++V GE S ++ S + K G
Sbjct: 177 LARFLSQLHADISNLKAMLRAIYIAGHATESFSDFVVGHGELWSAQMLSYAIQKSGTPCS 236
Query: 387 QYDAFEIGFITTDDFTNADILEATYPAVSKTLLNNWSKDKAVPVV-TGFLGKGWRSCAIT 563
D E+ + + A+ ++ Y K L +S+ A ++ TGF+ + T
Sbjct: 237 WMDTREVLVVNP---SGANQVDPDYLESEKRLEKWFSRCPAETIIATGFIASTPENIP-T 292
Query: 564 TLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYF 743
TL R GSD +A IG + R++ +W DVDGV + DP S A + L++ EA E++YF
Sbjct: 293 TLKRDGSDFSAAIIGSLVKARQVTIWTDVDGVFSADPRKVSEAVILSTLSYQEAWEMSYF 352
Query: 744 GAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTVI-----TRSRDMSKAVLTSIVLKRNV 908
GA VLHP ++ P +IP+ ++N +N +APGT+I + D+ V + + +
Sbjct: 353 GANVLHPRTIIPVMKYNIPIVIRNIFNTSAPGTMICQQPANENGDLEACVKAFATIDK-L 411
Query: 909 TMLDIASTRMLGQYGFLAKVFTTFEDLGISVDVV--ATSEVSISLTLDPAK---LWGREL 1073
++++ T M G G +F +D+G +V ++ A+SE S+ + P K L L
Sbjct: 412 ALVNVEGTGMAGVPGTANAIFGAVKDVGANVIMISQASSEHSVCFAV-PEKEVALVSAAL 470
Query: 1074 VQRANELDHVVEELEKIAVVKLLQRRSIISLIG-NVQKSSLILEKVFKVLRSNGVNVQMI 1250
R E +++ V+++ SI++ +G + + + +F L +NV+ I
Sbjct: 471 HARFRE----ALAAGRLSKVEVIHNCSILATVGLRMASTPGVSATLFDALAKANINVRAI 526
Query: 1251 SQGASKVNISLIVNDEEAEQCVRALHSAFF 1340
+QG S+ NI++++ E+ + +RA HS FF
Sbjct: 527 AQGCSEYNITIVLKQEDCVRALRAAHSRFF 556
>sp|O81852|AKH2_ARATH Bifunctional aspartokinase/homoserine dehydrogenase 2,
chloroplastic OS=Arabidopsis thaliana GN=AKHSDH2 PE=1 SV=1
Length = 916
Score = 159 bits (401), Expect = 6e-038
Identities = 117/447 (26%), Positives = 227/447 (50%), Gaps = 30/447 (6%)
Frame = +3
Query: 54 ERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHEL--GVETTV 227
ER ++V+SAM K T+ + KA + + + ++E + E H TA +L G +
Sbjct: 118 ERKLVVVSAMSKVTDMMYDLIRKAQSRDDSYLSALEA---VLEKHRLTARDLLDGDDLAS 174
Query: 228 IAQHL----EGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYD 395
HL L +L+ I + + D++ GE S ++ S + K G + + D
Sbjct: 175 FLSHLHNDISNLKAMLRAIYIAGHASESFSDFVAGHGELWSAQMLSYVVRKTGLECKWMD 234
Query: 396 AFEIGFI--TTDDFTNADILEATYPAVSKTLLNNW--SKDKAVPVVTGFLGKGWRSCAIT 563
++ + T+ + + D E S+ L+ W + + TGF+ ++ T
Sbjct: 235 TRDVLIVNPTSSNQVDPDFGE------SEKRLDKWFSLNPSKIIIATGFIASTPQNIP-T 287
Query: 564 TLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYF 743
TL R GSD +A +G L R++ +W DVDGV + DP + A + L++ EA E++YF
Sbjct: 288 TLKRDGSDFSAAIMGALLRARQVTIWTDVDGVYSADPRKVNEAVILQTLSYQEAWEMSYF 347
Query: 744 GAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLK-----RNV 908
GA VLHP ++ P +IP+ ++N +N +APGT+I + + + + +K N+
Sbjct: 348 GANVLHPRTIIPVMRYNIPIVIRNIFNLSAPGTIICQPPEDDYDLKLTTPVKGFATIDNL 407
Query: 909 TMLDIASTRMLGQYGFLAKVFTTFEDLGISVDVV--ATSEVSISLTLDPAKLWGRELVQR 1082
++++ T M G G + +F +D+G +V ++ A+SE S+ + ++ R
Sbjct: 408 ALINVEGTGMAGVPGTASDIFGCVKDVGANVIMISQASSEHSVCFAVPEKEVNAVSEALR 467
Query: 1083 ANELDHVVEELEKIAVVKLLQRRSIISLIGNVQKSSL-ILEKVFKVLRSNGVNVQMISQG 1259
+ + + + +++ ++++ SI++ +G S+ + +F L +NV+ ISQG
Sbjct: 468 SRFSEAL--QAGRLSQIEVIPNCSILAAVGQKMASTPGVSCTLFSALAKANINVRAISQG 525
Query: 1260 ASKVNISLIVNDEEAEQCVRALHSAFF 1340
S+ N+++++ E++ + +RA+HS FF
Sbjct: 526 CSEYNVTVVIKREDSVKALRAVHSRFF 552
>sp|Q9SA18|AKH1_ARATH Bifunctional aspartokinase/homoserine dehydrogenase 1,
chloroplastic OS=Arabidopsis thaliana GN=AKHSDH1 PE=1 SV=1
Length = 911
Score = 159 bits (400), Expect = 8e-038
Identities = 117/447 (26%), Positives = 219/447 (48%), Gaps = 30/447 (6%)
Frame = +3
Query: 54 ERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTA------HELGV 215
ER ++V+SAM K T+ + +A + + + LS + E H TA EL
Sbjct: 113 ERKLVVVSAMSKVTDMMYDLIHRAES---RDDSYLSALSGVLEKHRATAVDLLDGDELSS 169
Query: 216 ETTVIAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYD 395
+ + L +L+ I + T D++V GE S ++ +A + K G D
Sbjct: 170 FLARLNDDINNLKAMLRAIYIAGHATESFSDFVVGHGELWSAQMLAAVVRKSGLDCTWMD 229
Query: 396 AFEIGFI--TTDDFTNADILEATYPAVSKTLLNNWSKDKAVPVV--TGFLGKGWRSCAIT 563
A ++ + T+ + + D +E S+ L W + ++ TGF+ ++ T
Sbjct: 230 ARDVLVVIPTSSNQVDPDFVE------SEKRLEKWFTQNSAKIIIATGFIASTPQNIP-T 282
Query: 564 TLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYF 743
TL R GSD +A + ++ +W DVDGV + DP S A + L++ EA E++YF
Sbjct: 283 TLKRDGSDFSAAIMSALFRSHQLTIWTDVDGVYSADPRKVSEAVVLKTLSYQEAWEMSYF 342
Query: 744 GAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLK-----RNV 908
GA VLHP ++ P DIP+ ++N +N +APGT+I R D +K N+
Sbjct: 343 GANVLHPRTIIPVMKYDIPIVIRNIFNLSAPGTMICRQIDDEDGFKLDAPVKGFATIDNL 402
Query: 909 TMLDIASTRMLGQYGFLAKVFTTFEDLGISVDVV--ATSEVSISLTLDPAKLWGRELVQR 1082
++++ T M G G + +F+ +++G +V ++ A+SE S+ + ++ + + +
Sbjct: 403 ALVNVEGTGMAGVPGTASAIFSAVKEVGANVIMISQASSEHSVCFAVPEKEV--KAVSEA 460
Query: 1083 ANELDHVVEELEKIAVVKLLQRRSIISLIGNVQKSSL-ILEKVFKVLRSNGVNVQMISQG 1259
N +++ ++++ SI++ +G S+ + F L +N++ I+QG
Sbjct: 461 LNSRFRQALAGGRLSQIEIIPNCSILAAVGQKMASTPGVSATFFNALAKANINIRAIAQG 520
Query: 1260 ASKVNISLIVNDEEAEQCVRALHSAFF 1340
S+ NI+++V E+ + +RA+HS F+
Sbjct: 521 CSEFNITVVVKREDCIRALRAVHSRFY 547
>sp|P44505|AKH_HAEIN Bifunctional aspartokinase/homoserine dehydrogenase
OS=Haemophilus influenzae GN=thrA PE=3 SV=1
Length = 815
Score = 158 bits (397), Expect = 2e-037
Identities = 102/290 (35%), Positives = 161/290 (55%), Gaps = 13/290 (4%)
Frame = +3
Query: 489 NWSKDKAVPVVTGFLGKGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTC 668
N +KDK V ++ GF G + LGR GSD +A + LG ++W DVDGV TC
Sbjct: 178 NIAKDKVV-LMAGFTA-GNEKGELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTC 235
Query: 669 DPNIYSGAQSVPCLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTVI 848
DP + A+ +P L++ EA EL+YFGA+V+HP ++ P +IP +KN+ NP+APG++I
Sbjct: 236 DPRLVPDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGNPSAPGSII 295
Query: 849 TRSRDMSKAVLTSIVLKRNVTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDVV--ATSE 1022
+ + I N+ M +++ M G G ++VF+ GISV ++ ++SE
Sbjct: 296 DGNVKSESLQVKGITNLDNLAMFNVSGPGMQGMVGMASRVFSAMSGAGISVILITQSSSE 355
Query: 1023 VSISLTLDPAKLWGRELV---QRANELDHVVEELEKIAVVKLLQRRSIISLIGNVQKSSL 1193
SIS + + V + ANEL+ +LE I V+K L SIIS++G+ K +
Sbjct: 356 YSISFCVPVKSAEVAKTVLETEFANELNE--HQLEPIEVIKDL---SIISVVGDGMKQAK 410
Query: 1194 -ILEKVFKVLRSNGVNVQMISQGASKVNISLIVNDEEAEQCVRALHSAFF 1340
I + F L +++ I+QG+S+ +IS +V +A + V+A H A F
Sbjct: 411 GIAARFFSALAQANISIVAIAQGSSERSISAVVPQNKAIEAVKATHQALF 460
>sp|P27725|AK1H_SERMA Bifunctional aspartokinase/homoserine dehydrogenase 1
OS=Serratia marcescens GN=thrA PE=3 SV=1
Length = 819
Score = 156 bits (393), Expect = 5e-037
Identities = 126/439 (28%), Positives = 209/439 (47%), Gaps = 25/439 (5%)
Frame = +3
Query: 69 VLSAMGKTTNKLLKAGEKAVTCG--VTNVESIEELSFIKELHLRTAHEL-GVE----TTV 227
VLSA K TN L+ +K V + N+ E + +L A L G E V
Sbjct: 36 VLSAPAKITNHLVAMIDKTVAGQDILPNMSDAERI--FADLLSGLAQALPGFEYDRLKGV 93
Query: 228 IAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEI 407
+ Q L Q+L G+S++ + ++ GE +S + G+ + E
Sbjct: 94 VDQEFAQLKQVLHGVSLLGQCPDSVNAAIICRGEKLSIAIMEGVFRAKGYPVTVINPVE- 152
Query: 408 GFITTDDFTNADILEATYPAVSKTLLNNWSKDKA--VPVVTGFLGKGWRSCAITTLGRGG 581
LE+T TL + A + ++ GF G + LGR G
Sbjct: 153 -----KLLAQGHYLESTVDIAESTLRIAAAAIPADHIVLMAGFTA-GNDKGELVVLGRNG 206
Query: 582 SDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQVLH 761
SD +A + L ++W DVDGV TCDP A+ + +++ EA EL+YFGA+VLH
Sbjct: 207 SDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTVPDARLLKSMSYQEAMELSYFGAKVLH 266
Query: 762 PLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTRML 941
P ++ P IP +KN+ NP APGT+I + + + I N+ M++++ M
Sbjct: 267 PRTITPIAQFQIPCLIKNTSNPQAPGTLIGKDSTDADMPVKGITNLNNMAMINVSGPGMK 326
Query: 942 GQYGFLAKVFTTFEDLGISVDVV--ATSEVSISLTLDPAKLWGRELVQRANELDHVVEEL 1115
G G A+VF GISV ++ ++SE SIS + +L + +RA E + +E
Sbjct: 327 GMVGMAARVFAVMSRAGISVVLITQSSSEYSISFCVPQGEL---QRARRALEEEFYLELK 383
Query: 1116 EKIA-VVKLLQRRSIISLIGNVQKSSL-ILEKVFKVLRSNGVNVQMISQGASKVNISLIV 1289
+ + + +++R +IIS++G+ ++ I + F L +N+ I+QG+S+ +IS++V
Sbjct: 384 DGVLDPLDVMERLAIISVVGDGMRTLRGISARFFSALARANINIVAIAQGSSERSISVVV 443
Query: 1290 NDEEAEQCVRALHSAFFET 1346
+++ A VR H F T
Sbjct: 444 SNDSATTGVRVSHQMLFNT 462
>sp|Q8RQN1|AK_COREF Aspartokinase OS=Corynebacterium efficiens GN=lysC PE=3
SV=1
Length = 421
Score = 154 bits (387), Expect = 2e-036
Identities = 124/412 (30%), Positives = 211/412 (51%), Gaps = 26/412 (6%)
Frame = +3
Query: 135 GVTNVESIEELSFIKELHLRT---AHELGVETTVIAQHLEGLHQLLKGISMMKELTLRTR 305
G +++ES E + + E + T +++ V + + + L L ++ + R
Sbjct: 9 GGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLDLAAAVNPVP--PAREM 66
Query: 306 DYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLL 485
D L++ GE +S L + + +G +A+ + + G +TT+ NA I++ T V + L
Sbjct: 67 DMLLTAGERISNALVAMAIESLGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREAL- 125
Query: 486 NNWSKDKAVPVVTGFLGKGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLT 665
+ + +V GF G + +TTLGRGGSD TA + ALG +++ DVDGV T
Sbjct: 126 ----DEGKICIVAGFQGVNKETRDVTTLGRGGSDTTAVALAAALGADVCEIYSDVDGVYT 181
Query: 666 CDPNIYSGAQSVPCLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTV 845
DP I AQ + L+F+E ELA G+++L S+ AR ++P+RV++SY+ N PGT+
Sbjct: 182 ADPRIVPNAQKLERLSFEEMLELAAVGSKILVLRSVEYARAFNVPMRVRSSYS-NDPGTL 240
Query: 846 ITRSRD---MSKAVLTSIVLKRN---VTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDV 1007
I S + M +AVLT + ++ VT+L I + G AKVF D I++D+
Sbjct: 241 IAGSMEDIPMEEAVLTGVATDKSEAKVTVLGIPD-----KPGEAAKVFRALADAEINIDM 295
Query: 1008 VATSEVSI-SLTLDPAKLWGRELVQRANELDHVVEELEKIAVVKLLQRRSIISLIGNVQK 1184
V + S+ T D R RA EL +++ V + +SL+G K
Sbjct: 296 VLQNVSSVEDGTTDITFTCPRSDGPRAMELLKKMQQQGDWTNVLYDDQVGKVSLVGAGMK 355
Query: 1185 SSL-ILEKVFKVLRSNGVNVQMISQGASKVNISLIVNDEEAEQCVRALHSAF 1337
S + + + LR VNV++IS S++ IS+++ +++ ++ +ALH F
Sbjct: 356 SHPGVTAEFMEALRDVNVNVELIS--TSEIRISVLIREDDLDKSAKALHEKF 405
>sp|P26512|AK_CORGL Aspartokinase OS=Corynebacterium glutamicum GN=lysC PE=1
SV=2
Length = 421
Score = 151 bits (379), Expect = 2e-035
Identities = 121/412 (29%), Positives = 211/412 (51%), Gaps = 26/412 (6%)
Frame = +3
Query: 135 GVTNVESIEELSFIKELHLRT---AHELGVETTVIAQHLEGLHQLLKGISMMKELTLRTR 305
G +++ES E + + E + T +++ V + + + L +L ++ + R
Sbjct: 9 GGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVP--PAREM 66
Query: 306 DYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLL 485
D L++ GE +S L + + +G +A+ + + G +TT+ NA I++ T V + L
Sbjct: 67 DMLLTAGERISNALVAMAIESLGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREAL- 125
Query: 486 NNWSKDKAVPVVTGFLGKGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLT 665
+ + +V GF G + +TTLGRGGSD TA + AL +++ DVDGV T
Sbjct: 126 ----DEGKICIVAGFQGVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYT 181
Query: 666 CDPNIYSGAQSVPCLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTV 845
DP I AQ + L+F+E ELA G+++L S+ AR ++P+RV++SY+ N PGT+
Sbjct: 182 ADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYS-NDPGTL 240
Query: 846 ITRSRD---MSKAVLTSIVLKRN---VTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDV 1007
I S + + +AVLT + ++ VT+L I+ + G AKVF D I++D+
Sbjct: 241 IAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISD-----KPGEAAKVFRALADAEINIDM 295
Query: 1008 VATSEVSI-SLTLDPAKLWGRELVQRANELDHVVEELEKIAVVKLLQRRSIISLIGNVQK 1184
V + S+ T D R +RA E+ ++ V + +SL+G K
Sbjct: 296 VLQNVSSVEDGTTDITFTCPRSDGRRAMEILKKLQVQGNWTNVLYDDQVGKVSLVGAGMK 355
Query: 1185 SSL-ILEKVFKVLRSNGVNVQMISQGASKVNISLIVNDEEAEQCVRALHSAF 1337
S + + + LR VN+++IS S++ IS+++ +++ + RALH F
Sbjct: 356 SHPGVTAEFMEALRDVNVNIELIS--TSEIRISVLIREDDLDAAARALHEQF 405
>sp|P41398|AK_CORFL Aspartokinase OS=Corynebacterium flavum GN=lysC PE=1 SV=1
Length = 421
Score = 150 bits (378), Expect = 3e-035
Identities = 121/412 (29%), Positives = 211/412 (51%), Gaps = 26/412 (6%)
Frame = +3
Query: 135 GVTNVESIEELSFIKELHLRT---AHELGVETTVIAQHLEGLHQLLKGISMMKELTLRTR 305
G +++ES E + + E + T +++ V + + + L +L ++ + R
Sbjct: 9 GGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLELAAAVNPVP--PAREM 66
Query: 306 DYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLL 485
D L++ GE +S L + + +G +A+ + + G +TT+ NA I++ T V + L
Sbjct: 67 DMLLTAGERISNALVAMAIESLGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREAL- 125
Query: 486 NNWSKDKAVPVVTGFLGKGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLT 665
+ + +V GF G + +TTLGRGGSD TA + AL +++ DVDGV T
Sbjct: 126 ----DEGKICIVAGFQGVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYT 181
Query: 666 CDPNIYSGAQSVPCLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTV 845
DP I AQ + L+F+E ELA G+++L S+ AR ++P+RV++SY+ N PGT+
Sbjct: 182 ADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYS-NDPGTL 240
Query: 846 ITRSRD---MSKAVLTSIVLKRN---VTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDV 1007
I S + + +AVLT + ++ VT+L I+ + G AKVF D I++D+
Sbjct: 241 IAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISD-----KPGEAAKVFRALADAEINIDM 295
Query: 1008 VATSEVSI-SLTLDPAKLWGRELVQRANELDHVVEELEKIAVVKLLQRRSIISLIGNVQK 1184
V + S+ T D R +RA E+ ++ V + +SL+G K
Sbjct: 296 VLQNVSSVEDGTTDITFTCPRADGRRAMEILKKLQVQGNWTNVLYDDQVDKVSLVGAGMK 355
Query: 1185 SSL-ILEKVFKVLRSNGVNVQMISQGASKVNISLIVNDEEAEQCVRALHSAF 1337
S + + + LR VN+++IS S++ IS+++ +++ + RALH F
Sbjct: 356 SHPGVTAEFMEALRDVNVNIELIS--TSEIRISVLIREDDLDAAARALHEQF 405
>sp|P37142|AKH_DAUCA Bifunctional aspartokinase/homoserine dehydrogenase,
chloroplastic (Fragment) OS=Daucus carota PE=1 SV=1
Length = 921
Score = 148 bits (372), Expect = 1e-034
Identities = 123/450 (27%), Positives = 218/450 (48%), Gaps = 34/450 (7%)
Frame = +3
Query: 54 ERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEE-LSFIKELHLRTAHELGVE---- 218
ER ++V+SAM K T+ + KA + +S E L + E H TA +L E
Sbjct: 121 ERKLVVVSAMSKVTDMMYDLIYKA----QSRDDSYESALDAVMEKHKLTAFDLLDEDDLA 176
Query: 219 --TTVIAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQY 392
T + + L +L+ I + T D++V GE S +L S + K G
Sbjct: 177 RFLTRLQHDVITLKAMLRAIYIAGHATESFSDFVVGHGELWSAQLLSFVIRKNGGDCNWM 236
Query: 393 DAFEIGFITT--DDFTNADILEATYPAVSKTLLNNW--SKDKAVPVVTGFLGKGWRSCAI 560
D ++ + + + D LE S+ L W S V TGF+ ++
Sbjct: 237 DTRDVLVVNPAGSNQVDPDYLE------SEKRLEKWFSSNQCQTIVATGFIASTPQNIP- 289
Query: 561 TTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAY 740
TTL R GSD +A +G L ++ +W DV+GV + DP S A + L++ EA E++Y
Sbjct: 290 TTLKRDGSDFSAAIMGALLRAGQVTIWTDVNGVYSADPRKVSEAVVLKTLSYQEAWEMSY 349
Query: 741 FGAQVLHPLSMRPARDGDIPVRVKNSYNPNAPGTVITR-----SRDMSK--AVLTSIVLK 899
FGA VLHP ++ P DIP+ ++N +N +APGT+I R + D K + +
Sbjct: 350 FGANVLHPRTINPVMRYDIPIVIRNIFNLSAPGTMICRESVGETEDGLKLESHVKGFATI 409
Query: 900 RNVTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDVV--ATSEVSISLTLDPAKLWGREL 1073
N+ ++++ T M G G +F +D+G +V ++ A+SE SI + +++ + +
Sbjct: 410 DNLALINVEGTGMAGVPGTATAIFGAVKDVGANVIMISQASSEHSICFAVPESEV--KAV 467
Query: 1074 VQRANELDHVVEELEKIAVVKLLQRRSIISLIGNVQKSSL-ILEKVFKVLRSNGVNVQMI 1250
+ + +++ V SI++ +G S+ + +F L +NV+ I
Sbjct: 468 AKALEARFRQALDAGRLSQVANNPNCSILATVGQKMASTPGVSATLFNALAKANINVRAI 527
Query: 1251 SQGASKVNISLIVNDEEAEQCVRALHSAFF 1340
+QG ++ NI+++++ E+ + ++A+HS F+
Sbjct: 528 AQGCTEYNITVVLSREDCVRALKAVHSRFY 557
>sp|P0A4Z9|AK_MYCBO Aspartokinase OS=Mycobacterium bovis GN=ask PE=3 SV=1
Length = 421
Score = 146 bits (367), Expect = 5e-034
Identities = 115/358 (32%), Positives = 186/358 (51%), Gaps = 27/358 (7%)
Frame = +3
Query: 297 RTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSK 476
R D L++ GE +S L + + +G AR + + G ITT NA I++ T P +
Sbjct: 64 RELDMLLTAGERISNALVAMAIESLGAHARSFTGSQAGVITTGTHGNAKIIDVT-PGRLQ 122
Query: 477 TLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDG 656
T L ++ V +V GF G + +TTLGRGGSD TA + ALG +++ DVDG
Sbjct: 123 TAL----EEGRVVLVAGFQGVSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDG 178
Query: 657 VLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPNAP 836
+ + DP I A+ + +TF+E E+A GA+VL + AR +IPV V++SY+ + P
Sbjct: 179 IFSADPRIVRNARKLDTVTFEEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYS-DRP 237
Query: 837 GTVITRS-RD--MSKAVLTSIVLKRNVTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDV 1007
GTV+ S +D M +LT + R+ + I + G+ AKVF D +++D+
Sbjct: 238 GTVVVGSIKDVPMEDPILTGVAHDRSEAKVTIVGLPDIP--GYAAKVFRAVADADVNIDM 295
Query: 1008 VATSEVSI-----SLTLDPAKLWGRELVQRANELDHVVEELEKIAVVKLLQRRSI--ISL 1166
V + + +T ++ G V++ + L + +I +LL I +SL
Sbjct: 296 VLQNVSKVEDGKTDITFTCSRDVGPAAVEKLDSLRN------EIGFSQLLYDDHIGKVSL 349
Query: 1167 IGNVQKSSLILEKVF-KVLRSNGVNVQMISQGASKVNISLIVNDEEAEQCVRALHSAF 1337
IG +S + F + L + GVN+++IS S++ IS++ D E ++ V ALH AF
Sbjct: 350 IGAGMRSHPGVTATFCEALAAVGVNIELIS--TSEIRISVLCRDTELDKAVVALHEAF 405
>sp|P0A4Z8|AK_MYCTU Aspartokinase OS=Mycobacterium tuberculosis GN=ask PE=3
SV=1
Length = 421
Score = 146 bits (367), Expect = 5e-034
Identities = 115/358 (32%), Positives = 186/358 (51%), Gaps = 27/358 (7%)
Frame = +3
Query: 297 RTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSK 476
R D L++ GE +S L + + +G AR + + G ITT NA I++ T P +
Sbjct: 64 RELDMLLTAGERISNALVAMAIESLGAHARSFTGSQAGVITTGTHGNAKIIDVT-PGRLQ 122
Query: 477 TLLNNWSKDKAVPVVTGFLGKGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDG 656
T L ++ V +V GF G + +TTLGRGGSD TA + ALG +++ DVDG
Sbjct: 123 TAL----EEGRVVLVAGFQGVSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDG 178
Query: 657 VLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPNAP 836
+ + DP I A+ + +TF+E E+A GA+VL + AR +IPV V++SY+ + P
Sbjct: 179 IFSADPRIVRNARKLDTVTFEEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYS-DRP 237
Query: 837 GTVITRS-RD--MSKAVLTSIVLKRNVTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDV 1007
GTV+ S +D M +LT + R+ + I + G+ AKVF D +++D+
Sbjct: 238 GTVVVGSIKDVPMEDPILTGVAHDRSEAKVTIVGLPDIP--GYAAKVFRAVADADVNIDM 295
Query: 1008 VATSEVSI-----SLTLDPAKLWGRELVQRANELDHVVEELEKIAVVKLLQRRSI--ISL 1166
V + + +T ++ G V++ + L + +I +LL I +SL
Sbjct: 296 VLQNVSKVEDGKTDITFTCSRDVGPAAVEKLDSLRN------EIGFSQLLYDDHIGKVSL 349
Query: 1167 IGNVQKSSLILEKVF-KVLRSNGVNVQMISQGASKVNISLIVNDEEAEQCVRALHSAF 1337
IG +S + F + L + GVN+++IS S++ IS++ D E ++ V ALH AF
Sbjct: 350 IGAGMRSHPGVTATFCEALAAVGVNIELIS--TSEIRISVLCRDTELDKAVVALHEAF 405
>sp|Q8K9U9|AKH_BUCAP Bifunctional aspartokinase/homoserine dehydrogenase
OS=Buchnera aphidicola subsp. Schizaphis graminum GN=thrA PE=3 SV=1
Length = 814
Score = 145 bits (364), Expect = 1e-033
Identities = 116/440 (26%), Positives = 214/440 (48%), Gaps = 20/440 (4%)
Frame = +3
Query: 51 EERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKEL----HLRTAHELGVE 218
+E+ +VLSA K TN L E + V ++ + FI+ + ++
Sbjct: 30 KEQIAVVLSAPAKITNYLATIIENKIDDEVLKKINLAKNIFIELIQDIKRIQPLFPYENT 89
Query: 219 TTVIAQHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDA 398
+ I L +++ GI ++K+ + ++S GE +S + L H+ +
Sbjct: 90 KSTIEIEFNKLKKIINGILLIKQCPEGIKPIIISRGEILSVDIMKNILQSRNHEVTILNP 149
Query: 399 FEIGFITTDDFTNADILEATYP-AVSKTLLNNWSKD-KAVPVVTGFLGKGWRSCAITTLG 572
T+ + + L++T SK + + D K + ++ GF+ G + + LG
Sbjct: 150 ------VTNLLSIGNYLDSTIDIKESKKRIKKINIDQKNIILMAGFIA-GNKEGELVVLG 202
Query: 573 RGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYSGAQSVPCLTFDEAAELAYFGAQ 752
R GSD +A + L + ++W DVDGVLT DP I S + +++ EA EL+YFGA+
Sbjct: 203 RNGSDYSAAILASCLNAKCCEIWTDVDGVLTADPRIVSNTYLLDYISYQEAMELSYFGAK 262
Query: 753 VLHPLSMRPARDGDIPVRVKNSYNPNAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIAST 932
VLHP ++ P IP +KN+ N + GT I + + S L + N+ M +I+ +
Sbjct: 263 VLHPRTIEPISQFQIPCVIKNTNNTESKGTWIGKENNPSDNSLKGVTYLDNIIMFNISGS 322
Query: 933 RMLGQYGFLAKVFTTF--EDLGISVDVVATSEVSISL-TLDPAKLWGRELVQRANELDHV 1103
+ +A++FT E + I + + ++SE I+ T + + ++++ L+
Sbjct: 323 CLKDSGNTIARIFTILSRESMKIILIIQSSSENQINFCTFEKDIDYILLILKKEFTLEIK 382
Query: 1104 VEELEKIAVVKLLQRRSIISLIG-NVQKSSLILEKVFKVLRSNGVNVQMISQGASKVNIS 1280
L +VK L +I+S+IG N+ + + I K+F L S+ +NV I+ G+SK +IS
Sbjct: 383 EGLLNDFNIVKNL---TILSVIGSNISEKNNIASKIFSSLGSSKINVLAIAHGSSKHSIS 439
Query: 1281 LIVNDEEAEQCVRALHSAFF 1340
+++ E Q ++ +H+ F
Sbjct: 440 IVIKKENLLQGIQNIHNTLF 459
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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