BLASTX 7.6.2
Query= UN21692 /QuerySize=1280
(1279 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5ZLS7|GLYR1_CHICK Putative oxidoreductase GLYR1 OS=Gallus ga... 231 1e-059
sp|A4FUF0|GLYR1_BOVIN Putative oxidoreductase GLYR1 OS=Bos tauru... 230 2e-059
sp|Q5RKH0|GLYR1_RAT Putative oxidoreductase GLYR1 OS=Rattus norv... 230 3e-059
sp|Q49A26|GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=Homo sapi... 228 1e-058
sp|Q562D5|GLYR1_XENTR Putative oxidoreductase GLYR1 OS=Xenopus t... 227 1e-058
sp|Q5R7T2|GLYR1_PONAB Putative oxidoreductase GLYR1 OS=Pongo abe... 225 9e-058
sp|Q922P9|GLYR1_MOUSE Putative oxidoreductase GLYR1 OS=Mus muscu... 218 1e-055
sp|Q5RKN4|GLYR1_DANRE Putative oxidoreductase GLYR1 OS=Danio rer... 217 1e-055
sp|Q175F8|GLYR1_AEDAE Putative oxidoreductase GLYR1 homolog OS=A... 206 4e-052
sp|Q7Q161|GLYR1_ANOGA Putative oxidoreductase GLYR1 homolog OS=A... 198 9e-050
sp|P0ABQ3|GARR_ECOL6 2-hydroxy-3-oxopropionate reductase OS=Esch... 138 1e-031
sp|P0ABQ2|GARR_ECOLI 2-hydroxy-3-oxopropionate reductase OS=Esch... 138 1e-031
sp|P31937|3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenase, mitoch... 119 5e-026
sp|Q5R5E7|3HIDH_PONAB 3-hydroxyisobutyrate dehydrogenase, mitoch... 119 5e-026
sp|Q99L13|3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenase, mitoch... 118 1e-025
sp|Q2HJD7|3HIDH_BOVIN 3-hydroxyisobutyrate dehydrogenase, mitoch... 117 2e-025
sp|P29266|3HIDH_RAT 3-hydroxyisobutyrate dehydrogenase, mitochon... 117 3e-025
>sp|Q5ZLS7|GLYR1_CHICK Putative oxidoreductase GLYR1 OS=Gallus gallus GN=GLYR1
PE=2 SV=1
Length = 553
Score = 231 bits (587), Expect = 1e-059
Identities = 130/303 (42%), Positives = 188/303 (62%), Gaps = 7/303 (2%)
Frame = -3
Query: 1100 SSLQPTPSTKDELGSVS-----IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLI 936
+S+Q ST GS++ IGFLG+G+MGS + NL+K G V+VWNRT KCD I
Sbjct: 249 TSIQAADSTAVN-GSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFI 307
Query: 935 GLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAAS 756
GA+ +P EV +TCD+TFA ++DP++A D+ G +G + GI GK YVD+STVDA +
Sbjct: 308 QEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADT 367
Query: 755 SMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYL 579
+++ I G FLEAPVSG+++ + DG L+ L A Y + +L
Sbjct: 368 VTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFL 427
Query: 578 GDVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGP 399
G+VGN A M L+VNM+ GS MA+ AEG+ L+Q G L+++++QG + + K
Sbjct: 428 GEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQ 487
Query: 398 SMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
++++ + F LK+ QKD+RLA+ L +SV+ TP+AAAANE+YK AK+ SD D SAV
Sbjct: 488 NILQGNFKPDFYLKYIQKDLRLAIALGDSVNHPTPMAAAANEVYKRAKALDQSDNDMSAV 547
Query: 218 IEA 210
A
Sbjct: 548 YRA 550
>sp|A4FUF0|GLYR1_BOVIN Putative oxidoreductase GLYR1 OS=Bos taurus GN=GLYR1 PE=2
SV=1
Length = 553
Score = 230 bits (585), Expect = 2e-059
Identities = 130/303 (42%), Positives = 188/303 (62%), Gaps = 7/303 (2%)
Frame = -3
Query: 1100 SSLQPTPSTKDELGSVS-----IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLI 936
+S+Q ST GSV+ IGFLG+G+MGS + NL+K G V+VWNRT KCD I
Sbjct: 249 TSIQAADSTAVN-GSVTPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFI 307
Query: 935 GLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAAS 756
GA+ +P EV +TCD+TFA ++DP++A D+ G +G + GI GK YVD+STVDA +
Sbjct: 308 QEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADT 367
Query: 755 SMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYL 579
+++ I G FLEAPVSG+++ + DG L+ L A Y + +L
Sbjct: 368 VTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFL 427
Query: 578 GDVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGP 399
G+VGN A M L+VNM+ GS MA+ AEG+ L+Q G L+++++QG + + K
Sbjct: 428 GEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQ 487
Query: 398 SMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
++++ + F LK+ QKD+RLA+ L ++V+ TP+AAAANE+YK AK+ SD D SAV
Sbjct: 488 NILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAV 547
Query: 218 IEA 210
A
Sbjct: 548 YRA 550
>sp|Q5RKH0|GLYR1_RAT Putative oxidoreductase GLYR1 OS=Rattus norvegicus GN=Glyr1
PE=2 SV=1
Length = 552
Score = 230 bits (584), Expect = 3e-059
Identities = 129/303 (42%), Positives = 188/303 (62%), Gaps = 7/303 (2%)
Frame = -3
Query: 1100 SSLQPTPSTKDELGSVS-----IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLI 936
+S+Q ST GS++ IGFLG+G+MGS + NL+K G V+VWNRT KCD I
Sbjct: 248 TSIQAADSTAVN-GSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFI 306
Query: 935 GLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAAS 756
GA+ +P EV +TCD+TFA ++DP++A D+ G +G + GI GK YVD+STVDA +
Sbjct: 307 QEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADT 366
Query: 755 SMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYL 579
+++ I G FLEAPVSG+++ + DG L+ L A Y + +L
Sbjct: 367 VTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFL 426
Query: 578 GDVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGP 399
G+VGN A M L+VNM+ GS MA+ AEG+ L+Q G L+++++QG + + K
Sbjct: 427 GEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQ 486
Query: 398 SMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
++++ + F LK+ QKD+RLA+ L ++V+ TP+AAAANE+YK AK+ SD D SAV
Sbjct: 487 NILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAV 546
Query: 218 IEA 210
A
Sbjct: 547 YRA 549
>sp|Q49A26|GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=Homo sapiens GN=GLYR1
PE=1 SV=3
Length = 553
Score = 228 bits (579), Expect = 1e-058
Identities = 128/303 (42%), Positives = 187/303 (61%), Gaps = 7/303 (2%)
Frame = -3
Query: 1100 SSLQPTPSTKDELGSVS-----IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLI 936
+S+Q ST GS++ IGFLG+G+MGS + NL+K G V+VWNRT KCD I
Sbjct: 249 TSIQAADSTAVN-GSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFI 307
Query: 935 GLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAAS 756
GA+ +P EV +TCD+TFA ++DP++A D+ G +G + GI GK YVD+STVDA +
Sbjct: 308 QEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADT 367
Query: 755 SMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYL 579
+++ I G FLEAPVSG+++ + DG L+ L A Y + +L
Sbjct: 368 VTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFL 427
Query: 578 GDVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGP 399
G+VGN A M L+VNM+ GS MA+ AEG+ L+ G L+++++QG + + K
Sbjct: 428 GEVGNAAKMMLIVNMVQGSFMATIAEGLTLAHVTGQSQQTLLDILNQGQLASIFLDQKCQ 487
Query: 398 SMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
++++ + F LK+ QKD+RLA+ L ++V+ TP+AAAANE+YK AK+ SD D SAV
Sbjct: 488 NILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAV 547
Query: 218 IEA 210
A
Sbjct: 548 YRA 550
>sp|Q562D5|GLYR1_XENTR Putative oxidoreductase GLYR1 OS=Xenopus tropicalis
GN=glyr1 PE=2 SV=1
Length = 534
Score = 227 bits (578), Expect = 1e-058
Identities = 123/281 (43%), Positives = 176/281 (62%), Gaps = 1/281 (0%)
Frame = -3
Query: 1049 IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLTFA 870
IGFLG+G+MGS + NL+K G V+VWNRT KCD I GA +P EV +TCD+TFA
Sbjct: 251 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAHMGRTPAEVVSTCDITFA 310
Query: 869 MLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPVSG 690
+ADP++A D+ G +G + GI GK YVD+STVD + +++ I G FLEAPVSG
Sbjct: 311 CVADPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDPETVAELAQVIVSRGGRFLEAPVSG 370
Query: 689 SKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSMMA 513
+++ + DG L+ L A Y + +LG+VGN A M L++NM+ GS MA
Sbjct: 371 NQQLSNDGMLVILAAGDQGVYEDCSSCFLAMGKTSFFLGEVGNAARMMLILNMVQGSFMA 430
Query: 512 SFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGPSMIKSVYPTAFPLKHQQKDMRL 333
+ AEG+ L+Q G L+++++QG + + K ++++ + F LK+ QKD+RL
Sbjct: 431 TIAEGMTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRL 490
Query: 332 ALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAVIEA 210
A+ L +SV+ TP+AAAANE+YK AK+ SD D SAV A
Sbjct: 491 AIALGDSVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRA 531
>sp|Q5R7T2|GLYR1_PONAB Putative oxidoreductase GLYR1 OS=Pongo abelii GN=GLYR1
PE=2 SV=2
Length = 553
Score = 225 bits (571), Expect = 9e-058
Identities = 127/303 (41%), Positives = 187/303 (61%), Gaps = 7/303 (2%)
Frame = -3
Query: 1100 SSLQPTPSTKDELGSVS-----IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLI 936
+S+Q ST GS++ IGFLG+G+MGS + NL+K G V+VW+RT KCD I
Sbjct: 249 TSIQAADSTAVN-GSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWDRTAEKCDLFI 307
Query: 935 GLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAAS 756
GA+ +P EV +TCD+TFA ++DP++A D+ G +G + GI K YVD+STVDA +
Sbjct: 308 QEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPRKCYVDMSTVDADT 367
Query: 755 SMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYL 579
+++ I G FLEAPVSG+++ + DG L+ L A Y + +L
Sbjct: 368 VTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFL 427
Query: 578 GDVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGP 399
G+VGN A M L+VNM+ GS MA+ AEG+ L+Q G L+++++QG + + K
Sbjct: 428 GEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQ 487
Query: 398 SMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
++++ + F LK+ QKD+RLA+ L ++V+ TP+AAAANE+YK AK+ SD D SAV
Sbjct: 488 NILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAV 547
Query: 218 IEA 210
A
Sbjct: 548 YRA 550
>sp|Q922P9|GLYR1_MOUSE Putative oxidoreductase GLYR1 OS=Mus musculus GN=Glyr1
PE=2 SV=1
Length = 546
Score = 218 bits (553), Expect = 1e-055
Identities = 126/303 (41%), Positives = 185/303 (61%), Gaps = 13/303 (4%)
Frame = -3
Query: 1100 SSLQPTPSTKDELGSVS-----IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLI 936
+S+Q ST GS++ IGFLG+G+MGS + NL+K G V+VWNRT K
Sbjct: 248 TSIQAADSTAVN-GSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEK----- 301
Query: 935 GLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAAS 756
GA+ +P EV +TCD+TFA ++DP++A D+ G +G + GI GK YVD+STVDA +
Sbjct: 302 -EGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADT 360
Query: 755 SMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYL 579
+++ I G FLEAPVSG+++ + DG L+ L A Y + +L
Sbjct: 361 VTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFL 420
Query: 578 GDVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGP 399
G+VGN A M L+VNM+ GS MA+ AEG+ L+Q G L+++++QG + + K
Sbjct: 421 GEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQ 480
Query: 398 SMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
++++ + F LK+ QKD+RLA+ L ++V+ TP+AAAANE+YK AK+ SD D SAV
Sbjct: 481 NILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAV 540
Query: 218 IEA 210
A
Sbjct: 541 YRA 543
>sp|Q5RKN4|GLYR1_DANRE Putative oxidoreductase GLYR1 OS=Danio rerio GN=glyr1
PE=2 SV=1
Length = 462
Score = 217 bits (552), Expect = 1e-055
Identities = 123/304 (40%), Positives = 184/304 (60%), Gaps = 8/304 (2%)
Frame = -3
Query: 1100 SSLQPTPSTKDELGSVS-----IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLI 936
+S+Q ST GS++ IGFLG+G+MGS + NL+K G V+VWNRT KCD I
Sbjct: 157 TSIQAADSTAIN-GSITPTDKRIGFLGLGLMGSGVVSNLLKMGHVVTVWNRTAEKCDLFI 215
Query: 935 GLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAAS 756
GA+ +P EV + CD+TF+ ++DP++A D+ G +G + GI GK YV++STVD +
Sbjct: 216 QEGARLGRTPAEVVSMCDITFSCVSDPKAARDLVLGPSGVLQGIRPGKCYVEMSTVDPET 275
Query: 755 SMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTA-VISYYTKKLLLT*TSWEVKIYL 579
+S+ I G FLEAPVSGS++ + DG L+ + A S Y + ++
Sbjct: 276 ITELSQVITSRGGRFLEAPVSGSQQLSNDGMLVIVAAGDRSVYEDCSSCFQAMGKTSFFI 335
Query: 578 -GDVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKG 402
G+ GN A M L++NM+ GS MA+ AEG+ L+Q G ++++ QG + + K
Sbjct: 336 AGEAGNAARMMLILNMVQGSFMATIAEGLTLAQATGQSQQTFLDILCQGQMASTFVDQKC 395
Query: 401 PSMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSA 222
++++ + + LKH QKD+RLA+ + +SV+ TP+AAAANE+YK AK+ SD D SA
Sbjct: 396 QNILQGNFKPDYYLKHIQKDLRLAISMGDSVNHPTPMAAAANEVYKRAKALDQSDNDMSA 455
Query: 221 VIEA 210
V A
Sbjct: 456 VYRA 459
>sp|Q175F8|GLYR1_AEDAE Putative oxidoreductase GLYR1 homolog OS=Aedes aegypti
GN=AAEL006684 PE=3 SV=1
Length = 559
Score = 206 bits (522), Expect = 4e-052
Identities = 129/330 (39%), Positives = 185/330 (56%), Gaps = 18/330 (5%)
Frame = -3
Query: 1175 PVRFRPKPVS-----PFFSKPMFPLSYRVYSSLQPTPSTKDELGSVSIGFLGMGIMGSPM 1011
PVR R PVS P ++P P + S S + ++ GFLG+GIMG M
Sbjct: 231 PVR-RNVPVSHLLNRPTVARPATP-EIDMTSVSNALQSRNIQASNLKFGFLGLGIMGCGM 288
Query: 1010 AQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLTFAMLADPESAIDVAC 831
+NL+ +G V VWNRT +KC GA+ +P +V D+TF+ +ADP+ A ++
Sbjct: 289 VKNLLNSGHSVVVWNRTATKCRKFQEAGAEVADTPSDVIEMTDVTFSCVADPQVAKELVF 348
Query: 830 GKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPVSGSKKPAEDGQLIFL 651
G G +S GKGYV+++ VD +S I++QI G +LEA + GSK AE+G LI L
Sbjct: 349 GNCGVMSANLVGKGYVEMTGVDPETSHDIAEQIIAKGGRYLEAQIQGSKNQAEEGTLIIL 408
Query: 650 TAVISYYTKKLLL--T*TSWEV----KIYLGDVGNGAAMKLVVNMIMGSMMASFAEGILL 489
A ++LL T +E Y+GDVGN M LV+ MI G M+A AEG+ L
Sbjct: 409 AA-----GERLLFEECQTCFEAISRNSFYMGDVGNATKMNLVLQMISGVMLAGIAEGLAL 463
Query: 488 SQKVGLDPNVLVEVVSQGAINAPMYSLKGPSMIKSVYPTAFPLKHQQKDMRLALGLAESV 309
+ + GL ++EV+ ++++ + KG ++IK +P LKH QKD++LAL +AE +
Sbjct: 464 ADRAGLQQKDVLEVLELTSMSSELVMQKGNAIIKGEFPPQQALKHMQKDLKLALNMAEGL 523
Query: 308 SQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
Q PI AA+NE+YK AK G D SAV
Sbjct: 524 EQPLPITAASNEVYKHAKRLGYGSHDSSAV 553
>sp|Q7Q161|GLYR1_ANOGA Putative oxidoreductase GLYR1 homolog OS=Anopheles
gambiae GN=AGAP009949 PE=3 SV=5
Length = 566
Score = 198 bits (502), Expect = 9e-050
Identities = 111/283 (39%), Positives = 166/283 (58%), Gaps = 7/283 (2%)
Frame = -3
Query: 1055 VSIGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLT 876
+ GFLG+G+MG + +NLIK+G V VWNR+ KC +GA+ +P +V D+T
Sbjct: 281 LKFGFLGLGVMGCGIVKNLIKSGHSVVVWNRSAHKCRKFQEVGAEVADTPSDVVEMTDVT 340
Query: 875 FAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPV 696
++ ++DP+ A D+ G G +S +GKGYV+++ VD +S I++ I G +LEA +
Sbjct: 341 YSCVSDPQVAKDMVFGNCGVMSANLAGKGYVEMTGVDPETSNDINEAIISKGGRYLEAQI 400
Query: 695 SGSKKPAEDGQLIFLTAVISYYTKKLLLT*TSWEV----KIYLGDVGNGAAMKLVVNMIM 528
GSK AE+G LI L + ++ + +E YLGDVGN M L++ MI
Sbjct: 401 QGSKNQAEEGTLIILASGDRLLFEECQ---SCFEAISRNSFYLGDVGNATKMNLILQMIS 457
Query: 527 GSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGPSMIKSVYPTAFPLKHQQ 348
G +A AE + L+ + GL ++EV+ +++ M KG ++IK +PT LKH Q
Sbjct: 458 GITLAGVAEAMALADRAGLQQKDVLEVLELTNMSSEMMLQKGNAIIKGEFPTHHALKHMQ 517
Query: 347 KDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
KD++LAL LA+ + QS PI AA+NE+YK AK G D SAV
Sbjct: 518 KDLKLALSLADGLEQSLPITAASNEVYKHAKRLGYGSHDASAV 560
>sp|P0ABQ3|GARR_ECOL6 2-hydroxy-3-oxopropionate reductase OS=Escherichia coli O6
GN=garR PE=3 SV=1
Length = 294
Score = 138 bits (346), Expect = 1e-031
Identities = 80/280 (28%), Positives = 144/280 (51%), Gaps = 1/280 (0%)
Frame = -3
Query: 1055 VSIGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLT 876
+ +GF+G+GIMG PM++NL+KAG + V +R +I GA+ S+ + + CD+
Sbjct: 1 MKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVI 60
Query: 875 FAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPV 696
ML + +VA G+NG + G G +D+S++ +S IS+ +K G L+APV
Sbjct: 61 ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPV 120
Query: 695 SGSKKPAEDGQL-IFLTAVISYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSM 519
SG + A DG L + + + + K L ++ G++G G KL +I+
Sbjct: 121 SGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALN 180
Query: 518 MASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGPSMIKSVYPTAFPLKHQQKDM 339
+A+ +E + L+ K G++P+++ + + G + + K P ++ + F + KD+
Sbjct: 181 IAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDL 240
Query: 338 RLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
AL + V P+ AA E+ + ++ GL D SA+
Sbjct: 241 ANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSAL 280
>sp|P0ABQ2|GARR_ECOLI 2-hydroxy-3-oxopropionate reductase OS=Escherichia coli
(strain K12) GN=garR PE=1 SV=1
Length = 294
Score = 138 bits (346), Expect = 1e-031
Identities = 80/280 (28%), Positives = 144/280 (51%), Gaps = 1/280 (0%)
Frame = -3
Query: 1055 VSIGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLT 876
+ +GF+G+GIMG PM++NL+KAG + V +R +I GA+ S+ + + CD+
Sbjct: 1 MKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVI 60
Query: 875 FAMLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPV 696
ML + +VA G+NG + G G +D+S++ +S IS+ +K G L+APV
Sbjct: 61 ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPV 120
Query: 695 SGSKKPAEDGQL-IFLTAVISYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSM 519
SG + A DG L + + + + K L ++ G++G G KL +I+
Sbjct: 121 SGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALN 180
Query: 518 MASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGPSMIKSVYPTAFPLKHQQKDM 339
+A+ +E + L+ K G++P+++ + + G + + K P ++ + F + KD+
Sbjct: 181 IAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDL 240
Query: 338 RLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 219
AL + V P+ AA E+ + ++ GL D SA+
Sbjct: 241 ANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSAL 280
>sp|P31937|3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo
sapiens GN=HIBADH PE=1 SV=2
Length = 336
Score = 119 bits (297), Expect = 5e-026
Identities = 68/208 (32%), Positives = 111/208 (53%), Gaps = 3/208 (1%)
Frame = -3
Query: 1049 IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLTFA 870
+GF+G+G MG+PMA+NL+K G + +++ C G + SSP +V D
Sbjct: 42 VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIIT 101
Query: 869 MLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPVSG 690
ML +AI+ G NG + + G +D ST+D A S ++K+++ GA+F++APVSG
Sbjct: 102 MLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSG 161
Query: 689 SKKPAEDGQLIFLTAVI--SYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSMM 516
A G L F+ + + + LL V +Y G VG G A K+ NM++ M
Sbjct: 162 GVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNV-VYCGAVGTGQAAKICNNMLLAISM 220
Query: 515 ASFAEGILLSQKVGLDPNVLVEVVSQGA 432
AE + L ++GLDP +L ++++ +
Sbjct: 221 IGTAEAMNLGIRLGLDPKLLAKILNMSS 248
>sp|Q5R5E7|3HIDH_PONAB 3-hydroxyisobutyrate dehydrogenase, mitochondrial
OS=Pongo abelii GN=HIBADH PE=2 SV=1
Length = 336
Score = 119 bits (297), Expect = 5e-026
Identities = 68/208 (32%), Positives = 111/208 (53%), Gaps = 3/208 (1%)
Frame = -3
Query: 1049 IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLTFA 870
+GF+G+G MG+PMA+NL+K G + +++ C G + SSP +V D
Sbjct: 42 VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIIT 101
Query: 869 MLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPVSG 690
ML +AI+ G NG + + G +D ST+D A S ++K+++ GA+F++APVSG
Sbjct: 102 MLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSG 161
Query: 689 SKKPAEDGQLIFLTAVI--SYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSMM 516
A G L F+ + + + LL V +Y G VG G A K+ NM++ M
Sbjct: 162 GVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNV-VYCGAVGTGQAAKICNNMLLAISM 220
Query: 515 ASFAEGILLSQKVGLDPNVLVEVVSQGA 432
AE + L ++GLDP +L ++++ +
Sbjct: 221 IGTAEAMNLGIRLGLDPKLLAKILNMSS 248
>sp|Q99L13|3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Mus
musculus GN=Hibadh PE=2 SV=1
Length = 335
Score = 118 bits (294), Expect = 1e-025
Identities = 67/208 (32%), Positives = 111/208 (53%), Gaps = 3/208 (1%)
Frame = -3
Query: 1049 IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLTFA 870
+GF+G+G MG+PMA+NL+K G + +++ C G + SSP EV D
Sbjct: 41 VGFIGLGNMGNPMAKNLMKHGYPLILYDVFPDVCKEFKEAGEQVASSPAEVAEKADRIIT 100
Query: 869 MLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPVSG 690
ML +A++V G NG + + G +D ST+D + S ++K+++ GA+F++APVSG
Sbjct: 101 MLPSSMNAVEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKMGAVFMDAPVSG 160
Query: 689 SKKPAEDGQLIFLTAVI--SYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSMM 516
A G L F+ + + + LL V +Y G VG G + K+ NM++ M
Sbjct: 161 GVGAARSGNLTFMVGGVEDEFAAAQELLECMGSNV-VYCGAVGTGQSAKICNNMLLAISM 219
Query: 515 ASFAEGILLSQKVGLDPNVLVEVVSQGA 432
AE + L + GLDP +L ++++ +
Sbjct: 220 IGTAEAMNLGIRSGLDPKLLAKILNMSS 247
>sp|Q2HJD7|3HIDH_BOVIN 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Bos
taurus GN=HIBADH PE=2 SV=1
Length = 336
Score = 117 bits (293), Expect = 2e-025
Identities = 66/208 (31%), Positives = 111/208 (53%), Gaps = 3/208 (1%)
Frame = -3
Query: 1049 IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLTFA 870
+GF+G+G MG+PMA+NL+K G + +++ C + G + SSP +V D
Sbjct: 42 VGFIGVGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFLDAGEQVVSSPADVAEKADRIIT 101
Query: 869 MLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPVSG 690
ML +AI+ G NG + + G +D ST+D S ++K+++ GA+F++APVSG
Sbjct: 102 MLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPMVSKELAKEVEKMGAVFMDAPVSG 161
Query: 689 SKKPAEDGQLIFLTAVI--SYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSMM 516
A G L F+ + + + LL V +Y G VG G A K+ N+++ M
Sbjct: 162 GVGAARSGNLTFMVGGVEEEFAAAQELLGCMGSNV-VYCGAVGTGQAAKICNNLLLAISM 220
Query: 515 ASFAEGILLSQKVGLDPNVLVEVVSQGA 432
AE + L ++GLDP +L ++++ +
Sbjct: 221 IGTAEAMNLGIRLGLDPKLLAKILNMSS 248
>sp|P29266|3HIDH_RAT 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Rattus
norvegicus GN=Hibadh PE=1 SV=3
Length = 335
Score = 117 bits (291), Expect = 3e-025
Identities = 67/208 (32%), Positives = 112/208 (53%), Gaps = 3/208 (1%)
Frame = -3
Query: 1049 IGFLGMGIMGSPMAQNLIKAGCDVSVWNRTKSKCDPLIGLGAKYKSSPEEVTATCDLTFA 870
+GF+G+G MG+PMA+NLIK G + +++ C G + SSP +V D
Sbjct: 41 VGFIGLGNMGNPMAKNLIKHGYPLILYDVFPDVCKEFKEAGEQVASSPADVAEKADRIIT 100
Query: 869 MLADPESAIDVACGKNGAVSGISSGKGYVDVSTVDAASSMLISKQIKDTGALFLEAPVSG 690
ML ++I+V G NG + + G +D ST+D + S ++K+++ GA+F++APVSG
Sbjct: 101 MLPSSMNSIEVYSGANGILKKVKKGSLLIDSSTIDPSVSKELAKEVEKMGAVFMDAPVSG 160
Query: 689 SKKPAEDGQLIFLTAVI--SYYTKKLLLT*TSWEVKIYLGDVGNGAAMKLVVNMIMGSMM 516
A G L F+ + + + LL V +Y G VG+G + K+ NM++ M
Sbjct: 161 GVGAARSGNLTFMVGGVENEFAAAQELLGCMGSNV-LYCGAVGSGQSAKICNNMLLAISM 219
Query: 515 ASFAEGILLSQKVGLDPNVLVEVVSQGA 432
AE + L + GLDP +L ++++ +
Sbjct: 220 IGTAEAMNLGIRSGLDPKLLAKILNMSS 247
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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