BLASTX 7.6.2
Query= UN21781 /QuerySize=1104
(1103 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member ... 229 4e-059
sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member ... 228 7e-059
sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 ... 218 5e-056
sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member ... 218 7e-056
sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member ... 216 2e-055
sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member ... 213 2e-054
sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 ... 210 1e-053
sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member ... 209 4e-053
sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR famil... 191 9e-048
sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member ... 159 5e-038
sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger G... 120 2e-026
sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 116 3e-025
sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 116 3e-025
sp|O54438|FABG_PSEAE 3-oxoacyl-[acyl-carrier-protein] reductase ... 109 6e-023
sp|Q56318|Y019_THEMA Uncharacterized oxidoreductase TM_0019 OS=T... 104 1e-021
sp|P40398|YHXD_BACSU Uncharacterized oxidoreductase yhxD OS=Baci... 104 2e-021
sp|P16542|DHK1_STRVN Granaticin polyketide synthase putative ket... 92 8e-018
sp|Q92EK7|Y452_LISIN Uncharacterized oxidoreductase Lin0452 OS=L... 91 1e-017
sp|P25145|Y432_LISMO Uncharacterized oxidoreductase Lmo0432 OS=L... 89 4e-017
sp|Q9LTV6|DECR2_ARATH Peroxisomal 2,4-dienoyl-CoA reductase OS=A... 70 2e-011
>sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo
sapiens GN=DHRS4 PE=1 SV=2
Length = 260
Score = 229 bits (582), Expect = 4e-059
Identities = 123/249 (49%), Positives = 164/249 (65%), Gaps = 3/249 (1%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVA+VTAST GIGF I RL +GA VVVSSRKQ+NVD+AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ LV ++ +G IDI+V NAAVNP I+ E DK ++NVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMT 131
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRVNA 729
+ + P +EK G SV+ ++SIAAF P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 730 VAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGETLV 909
+APG++ T F+ + + E + +E + RLG +D A +FL S+DASYITGET+V
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVV 251
Query: 910 VAGGMPSRL 936
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member 4 OS=Pongo
abelii GN=DHRS4 PE=2 SV=2
Length = 260
Score = 228 bits (580), Expect = 7e-059
Identities = 122/249 (48%), Positives = 164/249 (65%), Gaps = 3/249 (1%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVA+VTAST GIGF I RL +GA VVVSSRKQ+NVD+AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ LV ++ +G IDI+V NAAVNP ++ E DK ++NVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 131
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRVNA 729
+ + P +EK G SV+ ++SIAAF P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 730 VAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGETLV 909
+APG++ T F+ + + E + +E + RLG +D A +FL S+DASYITGET+V
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVV 251
Query: 910 VAGGMPSRL 936
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 OS=Sus scrofa
GN=DHRS4 PE=1 SV=1
Length = 260
Score = 218 bits (555), Expect = 5e-056
Identities = 117/251 (46%), Positives = 160/251 (63%), Gaps = 3/251 (1%)
Frame = +1
Query: 193 KRLQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIV 372
K L+ KVA+VTAST GIG I RL +GA VVVSSRKQ NVD V L+ +G+ G V
Sbjct: 10 KPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTV 69
Query: 373 CHVSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSIL 552
CHV A+ R+ LV + +G +DI+V NAAVNP I+ E DK+ VNVK+++L
Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVL 129
Query: 553 LLQDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRV 723
+ + + P +EK G SV+ ++S+ A+ P Y V+KTALLGLTK LA E+ P + RV
Sbjct: 130 MTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRV 189
Query: 724 NAVAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGET 903
N +APG++ T+F+ + + + +E + RLG +D A +FL S+DASYITGET
Sbjct: 190 NCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGET 249
Query: 904 LVVAGGMPSRL 936
+VV GG SRL
Sbjct: 250 VVVGGGTASRL 260
>sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2 OS=Homo
sapiens GN=DHRS2 PE=1 SV=3
Length = 258
Score = 218 bits (554), Expect = 7e-056
Identities = 114/242 (47%), Positives = 155/242 (64%), Gaps = 2/242 (0%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L +VA+VT ST GIGF I RL +GA VV+SSRKQ+NVD A+ KL+ +G+ GIVCH
Sbjct: 12 LANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCH 71
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ LV K ++ G +D +VC+A VNP L T E DK+ VNVKS LLL
Sbjct: 72 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 131
Query: 559 QDMAPHLE-KGSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRVNAV 732
+ P++E + +VI ++SIAA+ P V +Y V+KTALLGLT+ LA E+ P D RVN V
Sbjct: 132 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCV 191
Query: 733 APGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGETLVV 912
PG++ T F+ N + + +E L R+G ++D A +FL S DASY+ GE + V
Sbjct: 192 VPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAV 251
Query: 913 AG 918
AG
Sbjct: 252 AG 253
>sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member 4
OS=Oryctolagus cuniculus GN=DHRS4 PE=1 SV=1
Length = 260
Score = 216 bits (550), Expect = 2e-055
Identities = 119/249 (47%), Positives = 159/249 (63%), Gaps = 3/249 (1%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVAIVTAST GIG I RL +GA VV+SSRKQ+NVD AV L+A+G+ G VCH
Sbjct: 12 LANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCH 71
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ LV + +G IDI+V NAAVNP ++ E DK+ ++NVK+ L+
Sbjct: 72 VGKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMT 131
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEM-GPDTRVNA 729
+ + P +EK G SV+ + SIAAF P Y V+KTAL+GLTK LA E+ + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNC 191
Query: 730 VAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGETLV 909
+APG++ T F+ + + +K + RLG ++ A +FL S+DASYITGET+V
Sbjct: 192 LAPGLIKTSFSKALWEDKAQEENIIQKLRIRRLGKPEECAGIVSFLCSEDASYITGETVV 251
Query: 910 VAGGMPSRL 936
VAGG PSRL
Sbjct: 252 VAGGAPSRL 260
>sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member 4 OS=Mus
musculus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 213 bits (542), Expect = 2e-054
Identities = 116/249 (46%), Positives = 158/249 (63%), Gaps = 3/249 (1%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVA+VTAST GIGF I RL +GA VVVSSRKQ+NVD AV L+ +G+ GIVCH
Sbjct: 12 LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCH 71
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ L+ ++R+ IDI+V NAAVNP ++ E DK+ +NV ++ +++
Sbjct: 72 VGKAEDREKLITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMI 131
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRVNA 729
+ + P +EK G SV+ + S+A F Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 730 VAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGETLV 909
+APG++ T F+S + +E + RLG +D A +FL S+DASYI GET+V
Sbjct: 192 LAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSEDASYINGETVV 251
Query: 910 VAGGMPSRL 936
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 OS=Rattus
norvegicus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 210 bits (534), Expect = 1e-053
Identities = 113/249 (45%), Positives = 158/249 (63%), Gaps = 3/249 (1%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVA+VTAST GIG I RL +GA VV+SSRKQ+NVD AV L+ +G+ G+VCH
Sbjct: 12 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCH 71
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ LV ++ + IDI+V NAAVNP ++ E +K+ +NV +S +++
Sbjct: 72 VGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMI 131
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRVNA 729
+ + P +EK G SV+ ++S+A F Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 730 VAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGETLV 909
+APG++ THF+S + + +E + RLG +D +FL S+DASYI GET+V
Sbjct: 192 LAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVV 251
Query: 910 VAGGMPSRL 936
V GG PSRL
Sbjct: 252 VGGGTPSRL 260
>sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 OS=Bos taurus
GN=DHRS4 PE=2 SV=1
Length = 260
Score = 209 bits (530), Expect = 4e-053
Identities = 113/249 (45%), Positives = 160/249 (64%), Gaps = 3/249 (1%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVA+VTAST GIGF I RL +GA VVVSSRKQ+NVD AV LK +G+ G VCH
Sbjct: 12 LDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCH 71
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ LV ++ +G +DI++ NAAV+P ++ E DK+ +VNVK++ LL
Sbjct: 72 VGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLT 131
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMG-PDTRVNA 729
+ + P + K G S++ ++SIAA+ P Y V+KTALLGLTK LA E+ + RVN
Sbjct: 132 KAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVRVNC 191
Query: 730 VAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGETLV 909
+APG++ T F+ + + + + + + R+G ++ A +FL S+DASYITGET+V
Sbjct: 192 LAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSEDASYITGETVV 251
Query: 910 VAGGMPSRL 936
VAGG S L
Sbjct: 252 VAGGSLSHL 260
>sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR family member 4-like
2 OS=Homo sapiens GN=DHRS4L1 PE=5 SV=1
Length = 281
Score = 191 bits (484), Expect = 9e-048
Identities = 108/252 (42%), Positives = 157/252 (62%), Gaps = 6/252 (2%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVA+VTAST IGF + +RL +GA VVVS RKQ+NVD+AV L+ +G+ G VCH
Sbjct: 30 LTNKVALVTASTDWIGFAVAQRLAQDGAHVVVSRRKQQNVDQAVATLQGEGLSMTGTVCH 89
Query: 379 VSNAQHRQILVQKTIQRYGKIDIV---VCNAAVNPSTDPILSTKEPALDKLWEVNVKSSI 549
V + + LV ++ +G IDI+ + N+ +L T E A D+ ++N K+
Sbjct: 90 VGKMKDWERLVATAMKLHGVIDILSLSITNSKRGLFWFTLLQTAEEAWDRNLDINGKALA 149
Query: 550 LLLQDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTR 720
L+++ + P +EK G SV F+ S+AAF+P + Y V+KTALLGL K LA E+ P + R
Sbjct: 150 LMIKAVVPEMEKRGGGSVGFLASVAAFRPLPGFSPYNVSKTALLGLNKTLAIELAPRNIR 209
Query: 721 VNAVAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITGE 900
VN +APG++ T F+ + + E + +E + RLG +D +FL S+DASY+TGE
Sbjct: 210 VNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDSLGIVSFLCSEDASYLTGE 269
Query: 901 TLVVAGGMPSRL 936
T++V GG PSRL
Sbjct: 270 TVMVGGGTPSRL 281
>sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member 4-like 2
OS=Homo sapiens GN=DHRS4L2 PE=2 SV=1
Length = 230
Score = 159 bits (400), Expect = 5e-038
Identities = 87/181 (48%), Positives = 117/181 (64%), Gaps = 3/181 (1%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L KVA+VTAST GIGF I RL + A VVVSSRKQ+NVD+AV L+ +G+ G VCH
Sbjct: 28 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 87
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V A+ R+ LV ++ +G IDI+V NAAVNP ++ E DK ++NVK+ L+
Sbjct: 88 VGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 147
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRVNA 729
+ + P +EK G SV+ ++SIAAF P + Y V+KTALLGL LA E+ P + RVN
Sbjct: 148 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNC 207
Query: 730 V 732
+
Sbjct: 208 L 208
>sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger GN=TR2 PE=2
SV=1
Length = 260
Score = 120 bits (300), Expect = 2e-026
Identities = 85/250 (34%), Positives = 136/250 (54%), Gaps = 12/250 (4%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L+G A+VT ++GIG+GIVE L GASV SR Q+ +DE + + +++G + VC
Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNVEASVCD 66
Query: 379 VSNAQHRQILVQKTIQR--YGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSIL 552
+S+ R+ + KT+ +GK++I+V NA + + T E + +N +++
Sbjct: 67 LSSRSEREEFM-KTVSNHFHGKLNILVNNAGIVIYKEAKDYTMED-YSHIMSINFEAAYH 124
Query: 553 LLQDMAPHLE--KGSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGPDT-RV 723
L P L+ + +V+FI+SI+ A+YG TK A+ LT+ LA E D RV
Sbjct: 125 LSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWAKDNIRV 184
Query: 724 NAVAPGVVPTHFASFITRNSEVRRANEEKTL----LNRLGTTDDMAAATAFLASDDASYI 891
N V PGV+ T ++ E ++ N +K + L R+G ++AA AFL ASY+
Sbjct: 185 NGVGPGVIATSMVEMTIQDPE-QKENLDKLIDRCALRRMGEPKELAAVVAFLCFPAASYV 243
Query: 892 TGETLVVAGG 921
TG+ + V GG
Sbjct: 244 TGQIIYVDGG 253
>sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
O157:H7 GN=hdhA PE=3 SV=1
Length = 255
Score = 116 bits (290), Expect = 3e-025
Identities = 85/249 (34%), Positives = 127/249 (51%), Gaps = 14/249 (5%)
Frame = +1
Query: 196 RLQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVC 375
RL GK AI+T + GIG I GASVVVS + V++++ G AF C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 376 HVSNAQHRQILVQKTIQRYGKIDIVVCNA---AVNPSTDPILSTKEPALDKLWEVNVKSS 546
+++ Q L I + GK+DI+V NA P P+ + + +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFR-----RAYELNVFSF 122
Query: 547 ILLLQDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMG-PDT 717
L Q +AP +EK G ++ ITS+AA + Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 718 RVNAVAPGVVPTH-FASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYIT 894
RVN +APG + T S IT E+ + + T + RLG D+A A FL S AS+++
Sbjct: 183 RVNGIAPGAILTDALKSVIT--PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240
Query: 895 GETLVVAGG 921
G+ L V+GG
Sbjct: 241 GQILTVSGG 249
>sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
(strain K12) GN=hdhA PE=1 SV=1
Length = 255
Score = 116 bits (290), Expect = 3e-025
Identities = 85/249 (34%), Positives = 127/249 (51%), Gaps = 14/249 (5%)
Frame = +1
Query: 196 RLQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVC 375
RL GK AI+T + GIG I GASVVVS + V++++ G AF C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 376 HVSNAQHRQILVQKTIQRYGKIDIVVCNA---AVNPSTDPILSTKEPALDKLWEVNVKSS 546
+++ Q L I + GK+DI+V NA P P+ + + +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFR-----RAYELNVFSF 122
Query: 547 ILLLQDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMG-PDT 717
L Q +AP +EK G ++ ITS+AA + Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 718 RVNAVAPGVVPTH-FASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYIT 894
RVN +APG + T S IT E+ + + T + RLG D+A A FL S AS+++
Sbjct: 183 RVNGIAPGAILTDALKSVIT--PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240
Query: 895 GETLVVAGG 921
G+ L V+GG
Sbjct: 241 GQILTVSGG 249
>sp|O54438|FABG_PSEAE 3-oxoacyl-[acyl-carrier-protein] reductase OS=Pseudomonas
aeruginosa GN=fabG PE=3 SV=1
Length = 247
Score = 109 bits (270), Expect = 6e-023
Identities = 84/249 (33%), Positives = 124/249 (49%), Gaps = 14/249 (5%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
LQGKVA+VT +++GIG I LG GA V+ ++ ++ E LKA G++ G+V
Sbjct: 3 LQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLD 62
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
VS+ + ++ Q G+ IVV NA + + ++ K+ + N+ S L
Sbjct: 63 VSSDESVAATLEHIQQHLGQPLIVVNNAGIT-RDNLLVRMKDDEWFDVVNTNLNSLYRLS 121
Query: 559 QDMAPHLEKG--SSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGPDT-RVNA 729
+ + + K +I I S+ Y K L G T+ALA E+G VNA
Sbjct: 122 KAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNA 181
Query: 730 VAPGVVPTHFASFITRNSEVRRANEEKTL----LNRLGTTDDMAAATAFLASDDASYITG 897
VAPG + T +TR E+ A E L L RLG +++A FLASD A+Y+TG
Sbjct: 182 VAPGFIDTD----MTR--ELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTG 235
Query: 898 ETLVVAGGM 924
T+ V GGM
Sbjct: 236 ATVPVNGGM 244
>sp|Q56318|Y019_THEMA Uncharacterized oxidoreductase TM_0019 OS=Thermotoga
maritima GN=TM_0019 PE=3 SV=2
Length = 256
Score = 104 bits (258), Expect = 1e-021
Identities = 76/252 (30%), Positives = 126/252 (50%), Gaps = 7/252 (2%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
L+GKVA+VT QGIG I + G VV++ + E E L+ +G+D +
Sbjct: 2 LEGKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEAGVEREEMLRERGLDVTFVKTD 61
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V++ + +V+KT++ YG +D++V NAAV S I +++ VN+ +
Sbjct: 62 VADENSVKNMVRKTVEIYGGVDVLVNNAAV-MSVKSIFERPLEEWERVIRVNLTGPYICS 120
Query: 559 QDMAPHLEK--GSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMGP-DTRVNA 729
+ A + K G +I I S AFQ + T Y +K L+ LT +LA + RV +
Sbjct: 121 RYCAEEMIKRGGGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLAVSLSRYHIRVVS 180
Query: 730 VAPGVVPTH--FASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDD-ASYITGE 900
++PG + T + + ++R + E+ R+G D+A FLA D+ A +ITG
Sbjct: 181 ISPGWIETSEWKKKSLRKKPDLRPIDHEQHPAGRVGNPLDIAHLCVFLADDEKAGFITGT 240
Query: 901 TLVVAGGMPSRL 936
+V GGM ++
Sbjct: 241 NFIVDGGMTVKM 252
>sp|P40398|YHXD_BACSU Uncharacterized oxidoreductase yhxD OS=Bacillus subtilis
GN=yhxD PE=3 SV=2
Length = 299
Score = 104 bits (257), Expect = 2e-021
Identities = 73/251 (29%), Positives = 121/251 (48%), Gaps = 6/251 (2%)
Frame = +1
Query: 196 RLQGKVAIVTASTQGIGFGIVERLGLEGASVVVS--SRKQRNVDEAVEKLKAQGIDAFGI 369
+L G+ A+VT GIG EGA V ++ +Q + +E E ++A+G A I
Sbjct: 48 KLTGRKALVTGGDSGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLI 107
Query: 370 VCHVSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSI 549
+S+ Q LV+++ G +D++ A + + I + K +EVNV S
Sbjct: 108 PGDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVFSLY 167
Query: 550 LLLQDMAPHLEKGSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEM-GPDTRVN 726
+++ P+L +G+S+I TS+ + P Y TK A++G T L ++ RVN
Sbjct: 168 WVVKAALPYLPEGASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIRVN 227
Query: 727 AVAPGVVPTHF---ASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASDDASYITG 897
+VAPG + T T N LNR G ++A FLAS+++SY+T
Sbjct: 228 SVAPGPIWTPLQISGGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVFLASENSSYVTS 287
Query: 898 ETLVVAGGMPS 930
+ + GG+P+
Sbjct: 288 QVYGITGGIPT 298
>sp|P16542|DHK1_STRVN Granaticin polyketide synthase putative ketoacyl reductase
1 OS=Streptomyces violaceoruber GN=gra-orf5 PE=3 SV=1
Length = 272
Score = 92 bits (226), Expect = 8e-018
Identities = 68/211 (32%), Positives = 106/211 (50%), Gaps = 15/211 (7%)
Frame = +1
Query: 211 VAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCHVSNA 390
VA+VT +T GIG I RL GA + +R + + + V++L+ +G D G VC V++
Sbjct: 19 VALVTGATSGIGLAIARRLAALGARTFLCARDEERLAQTVKELRGEGFDVDGTVCDVADP 78
Query: 391 QHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLW----EVNVKSSILLL 558
+ V +QRYG +DI+V NA + +T E A D+LW N+ S L+
Sbjct: 79 AQIRAYVAAAVQRYGTVDILVNNAGRSGGG----ATAEIA-DELWLDVITTNLTSVFLMT 133
Query: 559 QDM----APHLEKGSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKALAAEMG-PDTRV 723
+++ +K +I I S Q V Y +K ++GLTKAL E+ V
Sbjct: 134 KEVLNAGGMLAKKRGRIINIASTGGKQGVVHAVPYSASKHGVVGLTKALGLELARTGITV 193
Query: 724 NAVAPGVVPTHFASFITRN-SEVRRANEEKT 813
NAV PG V T A + + + + + +EE+T
Sbjct: 194 NAVCPGFVETPMAERVREHYAGIWQVSEEET 224
>sp|Q92EK7|Y452_LISIN Uncharacterized oxidoreductase Lin0452 OS=Listeria innocua
GN=lin0452 PE=3 SV=1
Length = 248
Score = 91 bits (224), Expect = 1e-017
Identities = 62/232 (26%), Positives = 117/232 (50%), Gaps = 11/232 (4%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
++ KV I+T ++ GIG L +GA +V+++R+ +++ V+ +KA +A
Sbjct: 3 IKNKVIIITGASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQTIKASSGEAIFAKTD 62
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V+ + + LV+ I+RYGK+D + NA + P++ P+ + KE +++ ++N+K + +
Sbjct: 63 VTKREDNKKLVELAIERYGKVDAIFLNAGIMPNS-PLSALKEDEWEQMIDINIKGVLNGI 121
Query: 559 QDMAPHL--EKGSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKAL---AAEMGPDTRV 723
+ P +K +I +S+A + A+YG TK A+ L + L +A+ G + R
Sbjct: 122 AAVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNIRT 181
Query: 724 NAVAPGVVPTHFASFIT-RNSEVRRANEEKTLLNRLGTTDDMAAATAFLASD 876
+ P + T IT + +E N L + G T D A+ A D
Sbjct: 182 ATIYPAAINTELLETITDKETEQGMTN----LYKQYGVTPDRIASIVAYAID 229
>sp|P25145|Y432_LISMO Uncharacterized oxidoreductase Lmo0432 OS=Listeria
monocytogenes GN=lmo0432 PE=3 SV=2
Length = 248
Score = 89 bits (220), Expect = 4e-017
Identities = 60/231 (25%), Positives = 115/231 (49%), Gaps = 9/231 (3%)
Frame = +1
Query: 199 LQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQGIDAFGIVCH 378
++ KV I+T ++ GIG L +GA +V+++R+ +++ V+ +KA +A
Sbjct: 3 IKNKVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQTIKANSGEAIFAKTD 62
Query: 379 VSNAQHRQILVQKTIQRYGKIDIVVCNAAVNPSTDPILSTKEPALDKLWEVNVKSSILLL 558
V+ + + LV+ I+RYGK+D + NA + P++ P+ + KE +++ ++N+K + +
Sbjct: 63 VTKREDNKKLVELAIERYGKVDAIFLNAGIMPNS-PLSALKEDEWEQMIDINIKGVLNGI 121
Query: 559 QDMAPHL--EKGSSVIFITSIAAFQPQVPTAMYGVTKTALLGLTKAL---AAEMGPDTRV 723
+ P +K +I +S+A + A+YG TK A+ L + L +A+ G + R
Sbjct: 122 AAVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNIRT 181
Query: 724 NAVAPGVVPTHFASFITRNSEVRRANEEKTLLNRLGTTDDMAAATAFLASD 876
+ P + T IT + +L + G T D A+ A D
Sbjct: 182 VTIYPAAINTELLETIT---DKETEQGMTSLYKQYGITPDRIASIVAYAID 229
>sp|Q9LTV6|DECR2_ARATH Peroxisomal 2,4-dienoyl-CoA reductase OS=Arabidopsis
thaliana GN=At3g12800 PE=2 SV=1
Length = 298
Score = 70 bits (171), Expect = 2e-011
Identities = 36/100 (36%), Positives = 60/100 (60%)
Frame = +1
Query: 172 MEKKKVPKRLQGKVAIVTASTQGIGFGIVERLGLEGASVVVSSRKQRNVDEAVEKLKAQG 351
M+ P ++G+VA++T GIGF I + G GAS+ + R+++ +D+AV L++ G
Sbjct: 1 MDSPFKPDVVRGQVALITGGGSGIGFEISSQFGKHGASIAIMGRRKQVLDDAVSALRSLG 60
Query: 352 IDAFGIVCHVSNAQHRQILVQKTIQRYGKIDIVVCNAAVN 471
I A G+ V + + +V+ T Q +GK+DI+V AA N
Sbjct: 61 IQAIGLEGDVRKQEDARRVVEATFQHFGKLDILVNAAAGN 100
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,891,173,716
Number of Sequences: 518415
Number of Extensions: 89891173716
Number of Successful Extensions: 595657870
Number of sequences better than 0.0: 0
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