BLASTX 7.6.2
Query= UN22016 /QuerySize=1587
(1586 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O23894|PRS6A_BRACM 26S protease regulatory subunit 6A homolog... 826 1e-238
sp|Q9SEI2|PS6AA_ARATH 26S protease regulatory subunit 6A homolog... 826 1e-238
sp|P54776|PRS6A_SOLLC 26S protease regulatory subunit 6A homolog... 784 5e-226
sp|P46465|PRS6A_ORYSJ 26S protease regulatory subunit 6A homolog... 773 9e-223
sp|O04019|PS6AB_ARATH 26S protease regulatory subunit 6A homolog... 773 1e-222
sp|Q63569|PRS6A_RAT 26S protease regulatory subunit 6A OS=Rattus... 649 2e-185
sp|P17980|PRS6A_HUMAN 26S protease regulatory subunit 6A OS=Homo... 649 2e-185
sp|O88685|PRS6A_MOUSE 26S protease regulatory subunit 6A OS=Mus ... 646 1e-184
sp|O42586|PR6AB_XENLA 26S protease regulatory subunit 6A-B OS=Xe... 639 2e-182
sp|P33297|PRS6A_YEAST 26S protease regulatory subunit 6A OS=Sacc... 584 6e-166
sp|O42587|PR6AA_XENLA 26S protease regulatory subunit 6A-A OS=Xe... 580 9e-165
sp|O14126|PRS6A_SCHPO 26S protease regulatory subunit 6A OS=Schi... 577 1e-163
sp|Q54PN7|PRS6A_DICDI 26S protease regulatory subunit 6A homolog... 532 5e-150
sp|Q8SR13|PRS6A_ENCCU 26S protease regulatory subunit 6A OS=Ence... 433 2e-120
sp|Q58576|PSMR_METJA Proteasome-activating nucleotidase OS=Metha... 352 4e-096
sp|Q8TX03|PSMR_METKA Proteasome-activating nucleotidase OS=Metha... 340 2e-092
sp|A3CV35|PSMR_METMJ Proteasome-activating nucleotidase OS=Metha... 331 9e-090
sp|P48601|PRS4_DROME 26S protease regulatory subunit 4 OS=Drosop... 329 4e-089
sp|P62191|PRS4_HUMAN 26S protease regulatory subunit 4 OS=Homo s... 329 4e-089
sp|P62192|PRS4_MOUSE 26S protease regulatory subunit 4 OS=Mus mu... 329 4e-089
>sp|O23894|PRS6A_BRACM 26S protease regulatory subunit 6A homolog OS=Brassica
campestris GN=TBP1 PE=2 SV=1
Length = 424
Score = 826 bits (2132), Expect = 1e-238
Identities = 421/424 (99%), Positives = 422/424 (99%)
Frame = +2
Query: 71 MATPMVEDTSSFEEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKEN 250
MATPMVEDTSSFEEDQLASMSTEDIVRATRLL+NEIRILKEDAQRTNLECDSYKEKIKEN
Sbjct: 1 MATPMVEDTSSFEEDQLASMSTEDIVRATRLLENEIRILKEDAQRTNLECDSYKEKIKEN 60
Query: 251 QEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLP 430
QEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLP
Sbjct: 61 QEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLP 120
Query: 431 VVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQI 610
VVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQI
Sbjct: 121 VVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQI 180
Query: 611 QELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQ 790
QELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQ
Sbjct: 181 QELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQ 240
Query: 791 LVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLN 970
LVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLN
Sbjct: 241 LVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLN 300
Query: 971 QLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNV 1150
QLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNV
Sbjct: 301 QLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNV 360
Query: 1151 HPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASL 1330
HPDVNFEELARSTDDFNGAQLKAVCVEAGMLA RDATEVNHEDFNEGIIQVQAKKKASL
Sbjct: 361 HPDVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASL 420
Query: 1331 NYYA 1342
NYYA
Sbjct: 421 NYYA 424
>sp|Q9SEI2|PS6AA_ARATH 26S protease regulatory subunit 6A homolog A
OS=Arabidopsis thaliana GN=RPT5A PE=2 SV=1
Length = 424
Score = 826 bits (2132), Expect = 1e-238
Identities = 421/424 (99%)
Frame = +2
Query: 71 MATPMVEDTSSFEEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKEN 250
MATPMVEDTSSFEEDQLASMSTEDI RATRLLDNEIRILKEDAQRTNLECDSYKEKIKEN
Sbjct: 1 MATPMVEDTSSFEEDQLASMSTEDITRATRLLDNEIRILKEDAQRTNLECDSYKEKIKEN 60
Query: 251 QEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLP 430
QEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLP
Sbjct: 61 QEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLP 120
Query: 431 VVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQI 610
VVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQI
Sbjct: 121 VVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQI 180
Query: 611 QELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQ 790
QELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQ
Sbjct: 181 QELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQ 240
Query: 791 LVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLN 970
LVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLN
Sbjct: 241 LVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLN 300
Query: 971 QLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNV 1150
QLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNV
Sbjct: 301 QLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNV 360
Query: 1151 HPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASL 1330
HPDVNFEELARSTDDFNGAQLKAVCVEAGMLA RDATEVNHEDFNEGIIQVQAKKKASL
Sbjct: 361 HPDVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASL 420
Query: 1331 NYYA 1342
NYYA
Sbjct: 421 NYYA 424
>sp|P54776|PRS6A_SOLLC 26S protease regulatory subunit 6A homolog OS=Solanum
lycopersicum GN=TBP1 PE=2 SV=1
Length = 423
Score = 784 bits (2023), Expect = 5e-226
Identities = 398/423 (94%), Positives = 415/423 (98%), Gaps = 1/423 (0%)
Frame = +2
Query: 74 ATPMVEDTSSFEEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQ 253
ATPM ED S+FE+DQL +MSTEDI+RA+RLLDNEIRI+KE+ QRTNLE DS+KEKIKENQ
Sbjct: 2 ATPMAED-SNFEDDQLHAMSTEDIIRASRLLDNEIRIIKEELQRTNLELDSFKEKIKENQ 60
Query: 254 EKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPV 433
EKIKLNKQLPYLVGNIVEILEMNPE++AEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPV
Sbjct: 61 EKIKLNKQLPYLVGNIVEILEMNPEEEAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPV 120
Query: 434 VGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQ 613
VGLVDPD+LKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDY+DIGGLEKQIQ
Sbjct: 121 VGLVDPDNLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYHDIGGLEKQIQ 180
Query: 614 ELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQL 793
ELVEAIVLPMTH+ERF+KLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQL
Sbjct: 181 ELVEAIVLPMTHQERFQKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQL 240
Query: 794 VQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQ 973
VQMFIGDGAKLVRDAFQLAKEK+PCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQ
Sbjct: 241 VQMFIGDGAKLVRDAFQLAKEKSPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQ 300
Query: 974 LDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVH 1153
LDGFSSD+RIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNV+
Sbjct: 301 LDGFSSDDRIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVN 360
Query: 1154 PDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASLN 1333
PDVNFEELARSTDDFNGAQLKAVCVEAGMLA RDATEV HEDFNEGIIQVQAKKKASLN
Sbjct: 361 PDVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVTHEDFNEGIIQVQAKKKASLN 420
Query: 1334 YYA 1342
YYA
Sbjct: 421 YYA 423
>sp|P46465|PRS6A_ORYSJ 26S protease regulatory subunit 6A homolog OS=Oryza
sativa subsp. japonica GN=TBP1 PE=2 SV=2
Length = 429
Score = 773 bits (1995), Expect = 9e-223
Identities = 389/412 (94%), Positives = 405/412 (98%)
Frame = +2
Query: 107 EEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPY 286
++DQLASMSTEDIVRATRLLDNE R+LK++ QRTNLE +SYKEKIKENQEKIKLNKQLPY
Sbjct: 18 DDDQLASMSTEDIVRATRLLDNETRVLKDELQRTNLEVESYKEKIKENQEKIKLNKQLPY 77
Query: 287 LVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKP 466
LVGNIVEILEMNPED+AEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPV+GLVDP+ LKP
Sbjct: 78 LVGNIVEILEMNPEDEAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVIGLVDPEKLKP 137
Query: 467 GDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMT 646
GDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMT
Sbjct: 138 GDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMT 197
Query: 647 HKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKL 826
HK+RF+KLG+RPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKL
Sbjct: 198 HKDRFQKLGIRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKL 257
Query: 827 VRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIK 1006
VRDAFQLAKEK+PCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIK
Sbjct: 258 VRDAFQLAKEKSPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIK 317
Query: 1007 VIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARS 1186
VIAATNRADILDPALMRSGRLDRKIEFPHP+EEARARILQIHSRKMNV+PDVNFEELARS
Sbjct: 318 VIAATNRADILDPALMRSGRLDRKIEFPHPSEEARARILQIHSRKMNVNPDVNFEELARS 377
Query: 1187 TDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASLNYYA 1342
TDDFNGAQLKAVCVEAGMLA RDATEV HEDFNEGIIQVQAKKK+SLNYYA
Sbjct: 378 TDDFNGAQLKAVCVEAGMLALRRDATEVTHEDFNEGIIQVQAKKKSSLNYYA 429
>sp|O04019|PS6AB_ARATH 26S protease regulatory subunit 6A homolog B
OS=Arabidopsis thaliana GN=RPT5B PE=1 SV=3
Length = 423
Score = 773 bits (1994), Expect = 1e-222
Identities = 396/423 (93%), Positives = 410/423 (96%), Gaps = 1/423 (0%)
Frame = +2
Query: 74 ATPMVEDTSSFEEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQ 253
AT M EDT SFE DQLASM+T+DI RA+RLL NEIRILKE++QRTNL+ +S KEKIKENQ
Sbjct: 2 ATAMAEDT-SFEGDQLASMTTDDIGRASRLLANEIRILKEESQRTNLDLESVKEKIKENQ 60
Query: 254 EKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPV 433
EKIKLNKQLPYLVGNIVEILEM+PEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPV
Sbjct: 61 EKIKLNKQLPYLVGNIVEILEMSPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPV 120
Query: 434 VGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQ 613
VGLVDPD+LKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQ
Sbjct: 121 VGLVDPDTLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQ 180
Query: 614 ELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQL 793
ELVEAIVLPMTHKE+FEKLG+RPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQL
Sbjct: 181 ELVEAIVLPMTHKEQFEKLGIRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQL 240
Query: 794 VQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQ 973
VQMFIGDGAKLVRDAF LAKEK+PCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQ
Sbjct: 241 VQMFIGDGAKLVRDAFLLAKEKSPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQ 300
Query: 974 LDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVH 1153
LDGFSSD+RIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEAR RILQIHSRKMNV+
Sbjct: 301 LDGFSSDDRIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARGRILQIHSRKMNVN 360
Query: 1154 PDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASLN 1333
DVNFEELARSTDDFNGAQLKAVCVEAGMLA RDATEVNHEDFNEGIIQVQAKKKASLN
Sbjct: 361 ADVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASLN 420
Query: 1334 YYA 1342
YYA
Sbjct: 421 YYA 423
>sp|Q63569|PRS6A_RAT 26S protease regulatory subunit 6A OS=Rattus norvegicus
GN=Psmc3 PE=2 SV=1
Length = 439
Score = 649 bits (1674), Expect = 2e-185
Identities = 325/425 (76%), Positives = 372/425 (87%), Gaps = 1/425 (0%)
Frame = +2
Query: 68 EMATPMVEDTSSFEEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKE 247
+MAT E +++ MSTE+IV+ TRLLD+EI+I+K + R E + K+KIKE
Sbjct: 16 KMATVWDEAEQDGIGEEVLKMSTEEIVQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKE 75
Query: 248 NQEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFL 427
N EKIK+NK LPYLV N++E+L+++P +D EEDGANIDLDSQRKGKC V+KTSTRQT FL
Sbjct: 76 NSEKIKVNKTLPYLVSNVIELLDVDP-NDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFL 134
Query: 428 PVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQ 607
PV+GLVD + LKPGDLVGVNKDSYLIL+TLP+EYDSRVKAMEVDE+PTE Y+DIGGL+KQ
Sbjct: 135 PVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQ 194
Query: 608 IQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGP 787
IQELVEAIVLPM HKE+FE LG++PPKGVL+YGPPGTGKTL+ARACAAQT ATFLKLAGP
Sbjct: 195 IQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGP 254
Query: 788 QLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELL 967
QLVQMFIGDGAKLVRDAF LAKEKAP IIFIDE+DAIGTKRFDSE +GDREVQRTMLELL
Sbjct: 255 QLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELL 314
Query: 968 NQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMN 1147
NQLDGF + ++KVIAATNR DILDPAL+RSGRLDRKIEFP P EEARARI+QIHSRKMN
Sbjct: 315 NQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMN 374
Query: 1148 VHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKAS 1327
V PDVN+EELAR TDDFNGAQ KAVCVEAGM+A R ATE+ HED+ EGI++VQAKKKA+
Sbjct: 375 VSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKAN 434
Query: 1328 LNYYA 1342
L YYA
Sbjct: 435 LQYYA 439
>sp|P17980|PRS6A_HUMAN 26S protease regulatory subunit 6A OS=Homo sapiens
GN=PSMC3 PE=1 SV=3
Length = 439
Score = 649 bits (1673), Expect = 2e-185
Identities = 324/425 (76%), Positives = 372/425 (87%), Gaps = 1/425 (0%)
Frame = +2
Query: 68 EMATPMVEDTSSFEEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKE 247
+MAT E +++ MSTE+I++ TRLLD+EI+I+K + R E + K+KIKE
Sbjct: 16 KMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKE 75
Query: 248 NQEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFL 427
N EKIK+NK LPYLV N++E+L+++P +D EEDGANIDLDSQRKGKC V+KTSTRQT FL
Sbjct: 76 NSEKIKVNKTLPYLVSNVIELLDVDP-NDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFL 134
Query: 428 PVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQ 607
PV+GLVD + LKPGDLVGVNKDSYLIL+TLP+EYDSRVKAMEVDE+PTE Y+DIGGL+KQ
Sbjct: 135 PVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQ 194
Query: 608 IQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGP 787
IQELVEAIVLPM HKE+FE LG++PPKGVL+YGPPGTGKTL+ARACAAQT ATFLKLAGP
Sbjct: 195 IQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGP 254
Query: 788 QLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELL 967
QLVQMFIGDGAKLVRDAF LAKEKAP IIFIDE+DAIGTKRFDSE +GDREVQRTMLELL
Sbjct: 255 QLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELL 314
Query: 968 NQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMN 1147
NQLDGF + ++KVIAATNR DILDPAL+RSGRLDRKIEFP P EEARARI+QIHSRKMN
Sbjct: 315 NQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMN 374
Query: 1148 VHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKAS 1327
V PDVN+EELAR TDDFNGAQ KAVCVEAGM+A R ATE+ HED+ EGI++VQAKKKA+
Sbjct: 375 VSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKAN 434
Query: 1328 LNYYA 1342
L YYA
Sbjct: 435 LQYYA 439
>sp|O88685|PRS6A_MOUSE 26S protease regulatory subunit 6A OS=Mus musculus
GN=Psmc3 PE=2 SV=1
Length = 442
Score = 646 bits (1666), Expect = 1e-184
Identities = 324/425 (76%), Positives = 371/425 (87%), Gaps = 1/425 (0%)
Frame = +2
Query: 68 EMATPMVEDTSSFEEDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKE 247
+MAT E +++ MSTE+IV+ TRLLD+EI+I+K + R E + K+KIKE
Sbjct: 19 KMATVWDEAEQDGIGEEVLKMSTEEIVQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKE 78
Query: 248 NQEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFL 427
N EKIK+NK LPYLV N++E+L+++P +D EEDGANIDLDSQRKGKC V+KTSTRQT FL
Sbjct: 79 NSEKIKVNKTLPYLVSNVIELLDVDP-NDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFL 137
Query: 428 PVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQ 607
PV+GLVD + LKPGDLVGVNKDSYLIL+TLP++YDSRVKAMEVDE+PTE Y+DIGGL+KQ
Sbjct: 138 PVIGLVDAEKLKPGDLVGVNKDSYLILETLPTDYDSRVKAMEVDERPTEQYSDIGGLDKQ 197
Query: 608 IQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGP 787
IQELVEAIVLPM HKE+FE LG++PPKGVL+YGPPGTGKTL+ARACAAQT ATFLKLAGP
Sbjct: 198 IQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGP 257
Query: 788 QLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELL 967
QLVQMFIGDGAKLVRDAF LAKEKAP IIFIDE+DAIGTKRFDSE +GDREVQRTMLELL
Sbjct: 258 QLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELL 317
Query: 968 NQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMN 1147
NQLDGF + ++KVIAATNR DILDPAL+RSGRLDRKIEFP P EEARARI+QIHSRKMN
Sbjct: 318 NQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMN 377
Query: 1148 VHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKAS 1327
V PDVN+EELAR TDDFNGAQ KAVCVEAGM+A R ATE+ HED EGI++VQAKKKA+
Sbjct: 378 VSPDVNYEELARCTDDFNGAQSKAVCVEAGMIALRRGATELTHEDHMEGILEVQAKKKAN 437
Query: 1328 LNYYA 1342
L YYA
Sbjct: 438 LQYYA 442
>sp|O42586|PR6AB_XENLA 26S protease regulatory subunit 6A-B OS=Xenopus laevis
GN=psmc3-b PE=2 SV=1
Length = 404
Score = 639 bits (1648), Expect = 2e-182
Identities = 316/404 (78%), Positives = 361/404 (89%), Gaps = 1/404 (0%)
Frame = +2
Query: 131 STEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYLVGNIVEI 310
STE+I++ TRLLD+EI+I+K + R E + ++KIKEN EKIK+NK LPYLV N++E+
Sbjct: 2 STEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMRDKIKENSEKIKVNKTLPYLVSNVIEL 61
Query: 311 LEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNK 490
L+++P +D EEDGANIDLDSQRKGKC V+KTSTRQT FLPV+GLVD + LKPGDLVGVNK
Sbjct: 62 LDVDP-NDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNK 120
Query: 491 DSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKL 670
DSYLIL+TLP+EYDSRVKAMEVDE+PTE Y+DIGGL+KQIQELVEAIVLPM HKE+FE L
Sbjct: 121 DSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENL 180
Query: 671 GVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLA 850
G++PPKGVL+YGPPGTGKTL+ARACAAQT ATFLKLAGPQLVQMFIGDGAKLVRDAF LA
Sbjct: 181 GIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFSLA 240
Query: 851 KEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRA 1030
KEKAP IIFIDE+DAIG KRFDSE +GDREVQRTMLELLNQLDGF ++KVIAATNR
Sbjct: 241 KEKAPSIIFIDELDAIGNKRFDSEKAGDREVQRTMLELLNQLDGFQPTTQVKVIAATNRV 300
Query: 1031 DILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARSTDDFNGAQ 1210
DILDPAL+RSGRLDRKIEFP P EEARARI+QIHSRKMNV PDVN+EELAR TDDFNGAQ
Sbjct: 301 DILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQ 360
Query: 1211 LKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASLNYYA 1342
KAVCVEAG++A R ATE+ HED+ EGI++VQAKKKA+L YYA
Sbjct: 361 CKAVCVEAGIIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 404
>sp|P33297|PRS6A_YEAST 26S protease regulatory subunit 6A OS=Saccharomyces
cerevisiae GN=RPT5 PE=1 SV=3
Length = 434
Score = 584 bits (1505), Expect = 6e-166
Identities = 289/416 (69%), Positives = 352/416 (84%), Gaps = 5/416 (1%)
Frame = +2
Query: 110 EDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYL 289
+ ++ ++ST+++ +LLDNEIRI + + QR + E + EKIK+N+EKIK N+QLPYL
Sbjct: 19 DQEILNLSTQELQTRAKLLDNEIRIFRSELQRLSHENNVMLEKIKDNKEKIKNNRQLPYL 78
Query: 290 VGNIVEILEMNPEDDAEE-----DGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPD 454
V N+VE+++MN +D E G N++LD+ GK V+KTS+RQT+FLP+VGLVDPD
Sbjct: 79 VANVVEVMDMNEIEDKENSESTTQGGNVNLDNTAVGKAAVVKTSSRQTVFLPMVGLVDPD 138
Query: 455 SLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIV 634
LKP DLVGVNKDSYLILDTLPSE+DSRVKAMEVDEKPTE Y+D+GGL+KQI+ELVEAIV
Sbjct: 139 KLKPNDLVGVNKDSYLILDTLPSEFDSRVKAMEVDEKPTETYSDVGGLDKQIEELVEAIV 198
Query: 635 LPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGD 814
LPM ++F+ +G+R PKG L+YGPPGTGKTL+ARACAAQTNATFLKLA PQLVQM+IG+
Sbjct: 199 LPMKRADKFKDMGIRAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAAPQLVQMYIGE 258
Query: 815 GAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSD 994
GAKLVRDAF LAKEKAP IIFIDE+DAIGTKRFDSE SGDREVQRTMLELLNQLDGFSSD
Sbjct: 259 GAKLVRDAFALAKEKAPTIIFIDELDAIGTKRFDSEKSGDREVQRTMLELLNQLDGFSSD 318
Query: 995 ERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEE 1174
+R+KV+AATNR D+LDPAL+RSGRLDRKIEFP P+E++RA+ILQIHSRKM D+N++E
Sbjct: 319 DRVKVLAATNRVDVLDPALLRSGRLDRKIEFPLPSEDSRAQILQIHSRKMTTDDDINWQE 378
Query: 1175 LARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASLNYYA 1342
LARSTD+FNGAQLKAV VEAGM+A + V HEDF EGI +VQA+K S+++YA
Sbjct: 379 LARSTDEFNGAQLKAVTVEAGMIALRNGQSSVKHEDFVEGISEVQARKSKSVSFYA 434
>sp|O42587|PR6AA_XENLA 26S protease regulatory subunit 6A-A OS=Xenopus laevis
GN=psmc3-a PE=2 SV=1
Length = 405
Score = 580 bits (1495), Expect = 9e-165
Identities = 291/385 (75%), Positives = 334/385 (86%), Gaps = 1/385 (0%)
Frame = +2
Query: 113 DQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYLV 292
+++ MSTE+I++ TRLLD+EI+I+K + R E + ++KIKEN EKIK+NK LPYLV
Sbjct: 15 EEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMRDKIKENSEKIKVNKTLPYLV 74
Query: 293 GNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPGD 472
N++E+L+++P +D EEDGANIDLDSQRKGKC V+KTSTRQT FLPV+GLVD + LKPGD
Sbjct: 75 SNVIELLDVDP-NDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGD 133
Query: 473 LVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHK 652
LVGVNKDSYLIL+TLP+EYDSRVKAMEVDE+PTE Y+DIGGL+KQIQELVEAIVLPM HK
Sbjct: 134 LVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHK 193
Query: 653 ERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVR 832
E+FE LG++PPKGVL+YGPPGTGKTL+ARACAAQT ATFLKLAGPQLVQMFIGDGAKLVR
Sbjct: 194 EKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVR 253
Query: 833 DAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVI 1012
DAF LAKEKAP IIFIDE+DAIGTKRFDSE +GDREVQRTMLELLNQLDGF + ++KVI
Sbjct: 254 DAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNMQVKVI 313
Query: 1013 AATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARSTD 1192
AATNR DILDPAL+RSGRLDRKIEFP P EEARARI+QIHSRKMNV PDVN+EELAR
Sbjct: 314 AATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCPT 373
Query: 1193 DFNGAQLKAVCVEAGMLAFCRDATE 1267
K VEAGM+A R ATE
Sbjct: 374 ISMALSAKQFGVEAGMIALRRGATE 398
>sp|O14126|PRS6A_SCHPO 26S protease regulatory subunit 6A OS=Schizosaccharomyces
pombe GN=tbp1 PE=2 SV=1
Length = 438
Score = 577 bits (1485), Expect = 1e-163
Identities = 283/411 (68%), Positives = 345/411 (83%)
Frame = +2
Query: 110 EDQLASMSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYL 289
E ++ + +++ TRLL+N+I+++K + QR E + EKIKENQEKI NK LPYL
Sbjct: 28 EQEILAAGIDELNSRTRLLENDIKVMKSEFQRLTHEKSTMLEKIKENQEKISNNKMLPYL 87
Query: 290 VGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPG 469
VGN+VEIL+M P++ ++ AN + ++ R GK V+KTSTRQTIFLP++GLV+P+ L PG
Sbjct: 88 VGNVVEILDMQPDEVDVQESANQNSEATRVGKSAVIKTSTRQTIFLPLIGLVEPEELHPG 147
Query: 470 DLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTH 649
DL+GVNKDSYLI+D LPSEYDSRVKAMEVDEKPTE Y+DIGGL KQI+EL EAIVLPM
Sbjct: 148 DLIGVNKDSYLIIDKLPSEYDSRVKAMEVDEKPTERYSDIGGLSKQIEELFEAIVLPMQQ 207
Query: 650 KERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLV 829
++F KLGV+PPKG L++GPPGTGKTL+ARACAAQ+NATFLKLA PQLVQMFIGDGAKLV
Sbjct: 208 ADKFRKLGVKPPKGCLMFGPPGTGKTLLARACAAQSNATFLKLAAPQLVQMFIGDGAKLV 267
Query: 830 RDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKV 1009
RDAF LAKEK+P IIFIDE+DAIGTKRFDSE +GDREVQRTMLELLNQLDGFSSD+R+KV
Sbjct: 268 RDAFALAKEKSPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSSDDRVKV 327
Query: 1010 IAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARST 1189
IAATNR D LDPAL+RSGRLDRK+EFP P EEAR IL+IHSRKM + D+N+EELARST
Sbjct: 328 IAATNRVDTLDPALLRSGRLDRKLEFPLPNEEARVGILRIHSRKMAIDDDINWEELARST 387
Query: 1190 DDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASLNYYA 1342
D++NGA LK+VCVEAGM+A + T++NHE F +GI++VQ +K +L Y+A
Sbjct: 388 DEYNGAMLKSVCVEAGMIALRQGDTKINHEHFMDGILEVQMRKSKTLQYFA 438
>sp|Q54PN7|PRS6A_DICDI 26S protease regulatory subunit 6A homolog
OS=Dictyostelium discoideum GN=psmC3 PE=1 SV=1
Length = 421
Score = 532 bits (1368), Expect = 5e-150
Identities = 263/320 (82%), Positives = 290/320 (90%)
Frame = +2
Query: 383 KCVVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDE 562
KCVV+K STRQTIFL G+VD D L+PGDLVG+NKDSY+ILDTLP EYDSRVKAME+DE
Sbjct: 102 KCVVVKASTRQTIFLAYPGIVDVDKLRPGDLVGINKDSYIILDTLPPEYDSRVKAMEIDE 161
Query: 563 KPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARA 742
KPTE+Y+DIGGL+KQIQELVEA+VLPMTHKERFE +G++PPKGVL+YGPPGTGKTL+ARA
Sbjct: 162 KPTEEYSDIGGLDKQIQELVEAVVLPMTHKERFESIGIKPPKGVLMYGPPGTGKTLLARA 221
Query: 743 CAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSE 922
CAAQTN+T+LKLAGPQLVQMFIGDGAKLVRDAF LAKEK P IIFIDE+DAIGTKRFDSE
Sbjct: 222 CAAQTNSTYLKLAGPQLVQMFIGDGAKLVRDAFALAKEKGPTIIFIDELDAIGTKRFDSE 281
Query: 923 VSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTE 1102
VSGDREVQRTMLELLNQLDGFSSD IKVIAATNR DILDPAL+RSGRLDRKIEFP P E
Sbjct: 282 VSGDREVQRTMLELLNQLDGFSSDANIKVIAATNRIDILDPALLRSGRLDRKIEFPLPNE 341
Query: 1103 EARARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHED 1282
EARA ILQIHSRKMNV DVNF+ELARS++DFNGAQLKAVCVEAGM+A R TE+ H D
Sbjct: 342 EARAHILQIHSRKMNVSADVNFDELARSSEDFNGAQLKAVCVEAGMIALRRGGTELIHND 401
Query: 1283 FNEGIIQVQAKKKASLNYYA 1342
F EG ++V AKKK +L YYA
Sbjct: 402 FVEGCVEVMAKKKKTLEYYA 421
>sp|Q8SR13|PRS6A_ENCCU 26S protease regulatory subunit 6A OS=Encephalitozoon
cuniculi GN=RPT5 PE=1 SV=1
Length = 401
Score = 433 bits (1112), Expect = 2e-120
Identities = 215/318 (67%), Positives = 260/318 (81%), Gaps = 2/318 (0%)
Frame = +2
Query: 392 VLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAM--EVDEK 565
V+ STR + +LP+ GL+ L+PGDLV ++KD+ ++ + LP +YD +V M + D K
Sbjct: 83 VVNASTRMSSYLPITGLIPNSELRPGDLVALHKDTNIVFEKLPPDYDMKVGGMVLKSDAK 142
Query: 566 PTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARAC 745
P E Y DIGGLE+QI+EL EAIVL +TH ERFEKL ++PPKGVL+YGPPGTGKTLMARAC
Sbjct: 143 PDETYEDIGGLERQIEELNEAIVLSLTHPERFEKLNIKPPKGVLMYGPPGTGKTLMARAC 202
Query: 746 AAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEV 925
A++TNATFLKLAGPQLVQM+IGDGA+LVRDAF LAKE+ P IIFIDEIDAIG KR DS+
Sbjct: 203 ASKTNATFLKLAGPQLVQMYIGDGARLVRDAFALAKERKPTIIFIDEIDAIGAKRSDSDQ 262
Query: 926 SGDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEE 1105
+GDREVQRTMLELLNQLDGFSS E +K+IAATNR DILDPAL+RSGRLDRKIEFP P
Sbjct: 263 TGDREVQRTMLELLNQLDGFSSSEEVKIIAATNRVDILDPALLRSGRLDRKIEFPLPNTL 322
Query: 1106 ARARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDF 1285
R RILQIH+RKM+V DVNF+ELARST+ FNGAQ KAVCVEAGM A ++ TE++ DF
Sbjct: 323 GRKRILQIHARKMSVRDDVNFDELARSTEGFNGAQCKAVCVEAGMAALRKEKTEISQNDF 382
Query: 1286 NEGIIQVQAKKKASLNYY 1339
+GI +V ++KK+ L Y+
Sbjct: 383 MDGIQEVLSRKKSKLLYF 400
>sp|Q58576|PSMR_METJA Proteasome-activating nucleotidase OS=Methanocaldococcus
jannaschii GN=pan PE=1 SV=1
Length = 430
Score = 352 bits (903), Expect = 4e-096
Identities = 191/414 (46%), Positives = 264/414 (63%), Gaps = 14/414 (3%)
Frame = +2
Query: 128 MSTEDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYLVGNIVE 307
+STE + + + E + KE +NL+ D KE+++E +L ++ L E
Sbjct: 7 ISTE-LKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLELEKKE 65
Query: 308 ILEMNPEDDAEEDGANIDLDSQR-------------KGKCVVLKTSTRQTIFLPVVGLVD 448
+ N + E + +LD R + VV+K+ST + + V V+
Sbjct: 66 LERENLQLMKENEILRRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNVSHFVN 125
Query: 449 PDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEA 628
PD L PG V +N+ + ++D LP D R KAMEVDE+P Y DIGGLEKQ+QE+ E
Sbjct: 126 PDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAMEVDERPNVRYEDIGGLEKQMQEIREV 185
Query: 629 IVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFI 808
+ LP+ H E FEK+G+ PPKG+LLYGPPGTGKTL+A+A A +TNATF+++ G +LV+ FI
Sbjct: 186 VELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSELVKKFI 245
Query: 809 GDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFS 988
G+GA LV+D F+LAKEKAP IIFIDEIDAI KR D+ GDREVQRT+++LL ++DGF
Sbjct: 246 GEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAEMDGFD 305
Query: 989 SDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNF 1168
+ +K+I ATNR DILDPA++R GR DR IE P P E+ R IL+IH+RKMN+ DVN
Sbjct: 306 ARGDVKIIGATNRPDILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLAEDVNL 365
Query: 1169 EELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKKASL 1330
EE+A+ T+ GA+LKA+C EAGM A V +DF + + ++ KKK +
Sbjct: 366 EEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVTMDDFRKAVEKIMEKKKVKV 419
>sp|Q8TX03|PSMR_METKA Proteasome-activating nucleotidase OS=Methanopyrus
kandleri GN=pan PE=3 SV=1
Length = 436
Score = 340 bits (871), Expect = 2e-092
Identities = 191/398 (47%), Positives = 258/398 (64%), Gaps = 13/398 (3%)
Frame = +2
Query: 137 EDIVRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQL---PYLVGNIVE 307
E++ R R + ++RI E +R LE KE E EK +L ++L ++ +
Sbjct: 38 EELERKLRAHEEKLRI--EARRRKTLE----KELEMERDEKAELREELRRKEVMIEKLRS 91
Query: 308 ILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVN 487
L+ + LD R V++K+ST V VD + L+PG V +N
Sbjct: 92 DLQRMKKPPLIVGTVEEILDDGR----VIVKSSTGPKFVSNVSPTVDRNELEPGANVALN 147
Query: 488 KDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEK 667
+ S ++D LPSE DSRV AMEVDE P Y+DIGGL++QI+E+ E + P+ E FEK
Sbjct: 148 QQSMAVVDVLPSEKDSRVLAMEVDESPDVSYDDIGGLDEQIREIREVVEKPLKEPELFEK 207
Query: 668 LGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQL 847
+GV PPKGVLLYGPPGTGKTL+A+A A +ATF++LA P+LVQ FIG+GA+LVR+ F+L
Sbjct: 208 VGVEPPKGVLLYGPPGTGKTLLAKAVANHADATFIRLAAPELVQKFIGEGARLVRELFEL 267
Query: 848 AKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVIAATNR 1027
A+EKAP IIFIDEIDAIG +R SGDREVQRT+ +LL ++DGF + IKVIAATNR
Sbjct: 268 AREKAPSIIFIDEIDAIGARRMRDATSGDREVQRTLTQLLAEMDGFDPLDDIKVIAATNR 327
Query: 1028 ADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARSTDDFNGA 1207
DILDPAL+R GR DR I+ P P EE R I +IH+R MN+ DV+ ++LA+ T+ +GA
Sbjct: 328 KDILDPALLRPGRFDRHIKIPLPDEEGRYEIFKIHTRDMNLAEDVDLQKLAKITEGASGA 387
Query: 1208 QLKAVCVEAGMLAFCRDATEVNHEDFNEGIIQVQAKKK 1321
+KA+C EAGM+A D V +DF + + +V KK+
Sbjct: 388 DIKAICTEAGMMAIREDRDIVTMDDFLKAVDRVMGKKE 425
>sp|A3CV35|PSMR_METMJ Proteasome-activating nucleotidase OS=Methanoculleus
marisnigri (strain ATCC 35101 / DSM 1498 / JR1) GN=pan PE=3 SV=1
Length = 412
Score = 331 bits (848), Expect = 9e-090
Identities = 164/303 (54%), Positives = 219/303 (72%)
Frame = +2
Query: 389 VVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKP 568
V++++S + L+DPD LKPG +N+ S I+D LP+ YD+++ ME+ E P
Sbjct: 89 VIVRSSAGPRFLVRTSQLIDPDLLKPGVRCTLNQQSLAIVDVLPTSYDAQIYGMELVESP 148
Query: 569 TEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACA 748
E Y +IGGLE QI+E+ EA+ LP+T + FEK+G+ PPKGVLLYGPPGTGKTL+ARA A
Sbjct: 149 EETYENIGGLEPQIEEIREAVELPLTKPQLFEKVGISPPKGVLLYGPPGTGKTLLARAVA 208
Query: 749 AQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVS 928
QTNA FL++ G +LVQ +IG+GA+LVR+ F LAK++AP IIFIDEIDAIG R DS S
Sbjct: 209 HQTNAHFLRVVGSELVQKYIGEGARLVRELFDLAKQRAPSIIFIDEIDAIGAHRNDSTTS 268
Query: 929 GDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEA 1108
GDREVQRT+++LL ++DGF + +K++AATNR DILD AL+R GR DR IE P P +
Sbjct: 269 GDREVQRTLMQLLAEMDGFDNRGDVKIVAATNRIDILDRALLRPGRFDRMIEIPLPDHQG 328
Query: 1109 RARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFN 1288
R IL+IH++ MN+ DVN E++R T+ NGA L+A+C+EAGM A + VN EDF
Sbjct: 329 RLAILKIHTQYMNIGEDVNLSEVSRLTEGKNGADLRAICMEAGMFAIRMERDAVNSEDFM 388
Query: 1289 EGI 1297
+ I
Sbjct: 389 KAI 391
>sp|P48601|PRS4_DROME 26S protease regulatory subunit 4 OS=Drosophila
melanogaster GN=Pros26.4 PE=1 SV=2
Length = 439
Score = 329 bits (843), Expect = 4e-089
Identities = 158/310 (50%), Positives = 222/310 (71%)
Frame = +2
Query: 392 VLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPT 571
++ TS ++ ++ VD D L+PG V +N + ++ L + D V M++++ P
Sbjct: 121 IVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLEKAPQ 180
Query: 572 EDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAA 751
E Y DIGGL+ QIQE+ E++ LP+TH E +E++G++PPKGV+LYGPPGTGKTL+A+A A
Sbjct: 181 ETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVAN 240
Query: 752 QTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSG 931
QT+ATFL++ G +L+Q ++GDG KLVR+ F++A+E AP I+FIDEIDA+GTKR+DS G
Sbjct: 241 QTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGG 300
Query: 932 DREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEAR 1111
+RE+QRTMLELLNQLDGF S +KVI ATNR + LDPAL+R GR+DRKIEFP P E+ +
Sbjct: 301 EREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTK 360
Query: 1112 ARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNE 1291
RI IH+ +M + DVN EL + DD +GA +KA+C EAG++A +V +EDF +
Sbjct: 361 RRIFTIHTSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKK 420
Query: 1292 GIIQVQAKKK 1321
V +KK
Sbjct: 421 SKESVLYRKK 430
>sp|P62191|PRS4_HUMAN 26S protease regulatory subunit 4 OS=Homo sapiens GN=PSMC1
PE=1 SV=1
Length = 440
Score = 329 bits (843), Expect = 4e-089
Identities = 159/310 (51%), Positives = 223/310 (71%)
Frame = +2
Query: 392 VLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPT 571
++ TS ++ ++ VD D L+PG V +N + ++ L + D V M+V++ P
Sbjct: 122 IVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQ 181
Query: 572 EDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAA 751
E Y DIGGL+ QIQE+ E++ LP+TH E +E++G++PPKGV+LYGPPGTGKTL+A+A A
Sbjct: 182 ETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVAN 241
Query: 752 QTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSG 931
QT+ATFL++ G +L+Q ++GDG KLVR+ F++A+E AP I+FIDEIDAIGTKR+DS G
Sbjct: 242 QTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGG 301
Query: 932 DREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEAR 1111
+RE+QRTMLELLNQLDGF S +KVI ATNR + LDPAL+R GR+DRKIEFP P E+ +
Sbjct: 302 EREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTK 361
Query: 1112 ARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNE 1291
RI QIH+ +M + DV ++L + DD +GA +KA+C EAG++A +V +EDF +
Sbjct: 362 KRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKK 421
Query: 1292 GIIQVQAKKK 1321
V KK+
Sbjct: 422 SKENVLYKKQ 431
>sp|P62192|PRS4_MOUSE 26S protease regulatory subunit 4 OS=Mus musculus GN=Psmc1
PE=1 SV=1
Length = 440
Score = 329 bits (843), Expect = 4e-089
Identities = 159/310 (51%), Positives = 223/310 (71%)
Frame = +2
Query: 392 VLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPT 571
++ TS ++ ++ VD D L+PG V +N + ++ L + D V M+V++ P
Sbjct: 122 IVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQ 181
Query: 572 EDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAA 751
E Y DIGGL+ QIQE+ E++ LP+TH E +E++G++PPKGV+LYGPPGTGKTL+A+A A
Sbjct: 182 ETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVAN 241
Query: 752 QTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSG 931
QT+ATFL++ G +L+Q ++GDG KLVR+ F++A+E AP I+FIDEIDAIGTKR+DS G
Sbjct: 242 QTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGG 301
Query: 932 DREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEAR 1111
+RE+QRTMLELLNQLDGF S +KVI ATNR + LDPAL+R GR+DRKIEFP P E+ +
Sbjct: 302 EREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTK 361
Query: 1112 ARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLAFCRDATEVNHEDFNE 1291
RI QIH+ +M + DV ++L + DD +GA +KA+C EAG++A +V +EDF +
Sbjct: 362 KRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKK 421
Query: 1292 GIIQVQAKKK 1321
V KK+
Sbjct: 422 SKENVLYKKQ 431
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,892,683,958
Number of Sequences: 518415
Number of Extensions: 92892683958
Number of Successful Extensions: 611291351
Number of sequences better than 0.0: 0
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