BLASTX 7.6.2
Query= UN22046 /QuerySize=1294
(1293 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54PY7|M2OM_DICDI Probable mitochondrial 2-oxoglutarate/malat... 228 1e-058
sp|Q9CR62|M2OM_MOUSE Mitochondrial 2-oxoglutarate/malate carrier... 225 7e-058
sp|Q02978|M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate carrier... 223 2e-057
sp|P22292|M2OM_BOVIN Mitochondrial 2-oxoglutarate/malate carrier... 223 4e-057
sp|P97700|M2OM_RAT Mitochondrial 2-oxoglutarate/malate carrier p... 216 4e-055
sp|P0C582|M2OM_NEUCR Putative mitochondrial 2-oxoglutarate/malat... 205 1e-051
sp|Q9UBX3|DIC_HUMAN Mitochondrial dicarboxylate carrier OS=Homo ... 168 1e-040
sp|Q9QZD8|DIC_MOUSE Mitochondrial dicarboxylate carrier OS=Mus m... 158 1e-037
sp|Q6FTN2|DIC1_CANGA Mitochondrial dicarboxylate transporter OS=... 141 2e-032
sp|Q06143|DIC1_YEAST Mitochondrial dicarboxylate transporter OS=... 134 1e-030
sp|B0G143|UCPB_DICDI Mitochondrial substrate carrier family prot... 117 2e-025
sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 OS=Bos t... 109 8e-023
sp|Q9N2I9|UCP3_CANFA Mitochondrial uncoupling protein 3 OS=Canis... 106 4e-022
sp|P56499|UCP3_RAT Mitochondrial uncoupling protein 3 OS=Rattus ... 101 2e-020
sp|P32332|OAC1_YEAST Mitochondrial oxaloacetate transport protei... 99 8e-020
sp|P56501|UCP3_MOUSE Mitochondrial uncoupling protein 3 OS=Mus m... 96 7e-019
>sp|Q54PY7|M2OM_DICDI Probable mitochondrial 2-oxoglutarate/malate carrier
protein OS=Dictyostelium discoideum GN=ucpC PE=3 SV=1
Length = 318
Score = 228 bits (579), Expect = 1e-058
Identities = 122/284 (42%), Positives = 170/284 (59%), Gaps = 11/284 (3%)
Frame = +2
Query: 173 VKPFVNGGTSGMLATCVIQPIDMIKVRIQL-GQGSAASVTSTMLK-------NEGIGAFY 328
+K FV GG +GML++ PID +KVR+QL G+G+ LK EG Y
Sbjct: 25 LKQFVIGGLAGMLSSAFTHPIDSLKVRMQLQGEGTGVGPKRGALKMLVHINQTEGFFTLY 84
Query: 329 KGLSAGLLRQATYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPA 508
KGLSA LLRQATYTT R G + ++ K A D KPLP QK + G+ +GA GA VG+PA
Sbjct: 85 KGLSASLLRQATYTTTRFGLYDLI--KDIVAKDDKPLPFTQKIMVGMLSGAGGAIVGTPA 142
Query: 509 DLALIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLA 688
DL ++RMQAD LP RRNY N F ++RIS +EG+++LWKGC P ++RAM + G ++
Sbjct: 143 DLTMVRMQADGKLPFNLRRNYKNVFDGIFRISKEEGIISLWKGCSPNLIRAMFMTAGQVS 202
Query: 689 SYDQSAEYM-RDNLGLGETSTVVGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPY 865
SYDQ+ + M + T + AS + F AA + P D +KT+I G+ Y
Sbjct: 203 SYDQTKQLMLASGYFHDDIKTHLIASTTAAFVAAVATSPLDVIKTRIMNSPKTVTGELQY 262
Query: 866 TGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQI 997
G+ DC +TL++ G FY GF Y +R+ P ++T+IF+ Q+
Sbjct: 263 KGTFDCLSKTLRAEGFKAFYKGFNPYFMRLGPQTILTFIFVEQL 306
>sp|Q9CR62|M2OM_MOUSE Mitochondrial 2-oxoglutarate/malate carrier protein OS=Mus
musculus GN=Slc25a11 PE=1 SV=3
Length = 314
Score = 225 bits (572), Expect = 7e-058
Identities = 128/288 (44%), Positives = 177/288 (61%), Gaps = 11/288 (3%)
Frame = +2
Query: 182 FVNGGTSGMLATCVIQPIDMIKVRIQL-GQG-------SAASVTSTMLKNEGIGAFYKGL 337
F+ GG +GM AT +QP+D++K R+QL G+G ++ +++LK EG+ Y GL
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKGIYTGL 84
Query: 338 SAGLLRQATYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLA 517
SAGLLRQATYTT RLG + +L + + A DG P KAL G+TAGA GA VG+PA++A
Sbjct: 85 SAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKALIGMTAGATGAFVGTPAEVA 143
Query: 518 LIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLASYD 697
LIRM AD LP QRR Y N F+AL RI+ +EGV LW+GC PT+ RA+ +N LASY
Sbjct: 144 LIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYS 203
Query: 698 QSAEYMRDNLGLGETSTV-VGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPYTGS 874
QS +++ D+ + AS +SG A S+P D VKT+IQ M+ GK Y
Sbjct: 204 QSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNMRM-IDGKPEYKNG 262
Query: 875 LDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITKFQKTI 1018
LD ++ ++ G + GF Y R+ PH ++T+IFL Q+ K K +
Sbjct: 263 LDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310
>sp|Q02978|M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate carrier protein
OS=Homo sapiens GN=SLC25A11 PE=1 SV=3
Length = 314
Score = 223 bits (568), Expect = 2e-057
Identities = 127/288 (44%), Positives = 176/288 (61%), Gaps = 11/288 (3%)
Frame = +2
Query: 182 FVNGGTSGMLATCVIQPIDMIKVRIQL-GQG-------SAASVTSTMLKNEGIGAFYKGL 337
F+ GG +GM AT +QP+D++K R+QL G+G ++ +++LK EG+ Y GL
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGL 84
Query: 338 SAGLLRQATYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLA 517
SAGLLRQATYTT RLG + +L + + A DG P KA+ G+TAGA GA VG+PA++A
Sbjct: 85 SAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKAVIGMTAGATGAFVGTPAEVA 143
Query: 518 LIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLASYD 697
LIRM AD LP QRR Y N F+AL RI+ +EGVL LW+GC PT+ RA+ +N LASY
Sbjct: 144 LIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYS 203
Query: 698 QSAEYMRDNLGLGETSTV-VGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPYTGS 874
QS +++ D+ + AS +SG A S+P D KT+IQ M+ GK Y
Sbjct: 204 QSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRM-IDGKPEYKNG 262
Query: 875 LDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITKFQKTI 1018
LD + ++ G + GF Y R+ PH ++T+IFL Q+ K K +
Sbjct: 263 LDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310
>sp|P22292|M2OM_BOVIN Mitochondrial 2-oxoglutarate/malate carrier protein OS=Bos
taurus GN=SLC25A11 PE=1 SV=3
Length = 314
Score = 223 bits (566), Expect = 4e-057
Identities = 127/288 (44%), Positives = 176/288 (61%), Gaps = 11/288 (3%)
Frame = +2
Query: 182 FVNGGTSGMLATCVIQPIDMIKVRIQL-GQGSAASVTST-------MLKNEGIGAFYKGL 337
F+ GG +GM AT +QP+D++K R+QL G+G+ T +L+ EG+ Y GL
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALISILRAEGLRGIYTGL 84
Query: 338 SAGLLRQATYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLA 517
SAGLLRQATYTT RLG + +L + + A DG P KA+ G+TAGA GA VG+PA++A
Sbjct: 85 SAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKAVIGMTAGATGAFVGTPAEVA 143
Query: 518 LIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLASYD 697
LIRM AD LP+ QRR Y N F+AL+RI +EGV LW+GC PT+ RA+ +N LASY
Sbjct: 144 LIRMTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQLASYS 203
Query: 698 QSAEYMRDNLGLGETSTV-VGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPYTGS 874
QS +++ D+ + AS +SG A S+P D VKT+IQ M+ GK Y
Sbjct: 204 QSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNMRM-IDGKPEYKNG 262
Query: 875 LDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITKFQKTI 1018
LD ++ ++ G + GF Y R+ PH ++T+IFL Q+ K K +
Sbjct: 263 LDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310
>sp|P97700|M2OM_RAT Mitochondrial 2-oxoglutarate/malate carrier protein
OS=Rattus norvegicus GN=Slc25a11 PE=2 SV=3
Length = 314
Score = 216 bits (548), Expect = 4e-055
Identities = 125/288 (43%), Positives = 173/288 (60%), Gaps = 11/288 (3%)
Frame = +2
Query: 182 FVNGGTSGMLATCVIQPIDMIKVRIQL-GQG-------SAASVTSTMLKNEGIGAFYKGL 337
F+ GG +GM AT +QP+D++ R+QL G+G ++ +++LK EG+ Y GL
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVXNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGL 84
Query: 338 SAGLLRQATYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLA 517
SAGLLRQATYTT RLG + +L + + A DG P KAL G+TAGA GA VG PA++A
Sbjct: 85 SAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKALIGMTAGATGAFVGPPAEVA 143
Query: 518 LIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLASYD 697
LIRM AD LP QRR Y N F+AL RI+ +EGV LW+GC PT+ RA+ +N LASY
Sbjct: 144 LIRMTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYS 203
Query: 698 QSAEYMRDNLGLGETSTV-VGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPYTGS 874
QS +++ D+ + A +SG A S+P D VKT+IQ M+ K Y
Sbjct: 204 QSKQFLLDSGYFSDNILCHFCAIMISGLVTTAASMPVDIVKTRIQNMRM-IDEKPEYKNG 262
Query: 875 LDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITKFQKTI 1018
LD ++ ++ G + GF Y R+ PH ++T+IFL Q+ K K +
Sbjct: 263 LDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310
>sp|P0C582|M2OM_NEUCR Putative mitochondrial 2-oxoglutarate/malate carrier
protein OS=Neurospora crassa GN=NCU10732 PE=3 SV=1
Length = 331
Score = 205 bits (519), Expect = 1e-051
Identities = 111/233 (47%), Positives = 146/233 (62%), Gaps = 9/233 (3%)
Frame = +2
Query: 326 YKGLSAGLLRQATYTTARLGSF----KMLTAKASEANDGKPLPLYQKALCGLTAGAIGAC 493
Y GLSAGLLRQA YTTAR+G F L+A+A E G+ + ++A GL AG + A
Sbjct: 101 YTGLSAGLLRQAVYTTARIGCFDTFMSRLSARAKE--KGQSVGFKERASAGLAAGGLAAM 158
Query: 494 VGSPADLALIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALN 673
+G+PADLALIRMQ+D P+A+R+NY + AL I+ +EGV ALW G PTVVRAMALN
Sbjct: 159 IGNPADLALIRMQSDGLKPVAERKNYKSVIDALGGIARNEGVAALWAGAAPTVVRAMALN 218
Query: 674 MGMLASYDQSAEYMRDNLGLGETSTVVGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQG 853
G LA + ++ ++ + ASA++GF A+ SLPFDFVKT++QK G
Sbjct: 219 FGQLAFFSEAKAQLKARTQWSSKVQTLSASAIAGFFASFFSLPFDFVKTRLQKQTRGPDG 278
Query: 854 KYPYTGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWI---FLNQITK 1003
K PY G +DC + K G +FY GF Y VRIAPH M+T + +L +TK
Sbjct: 279 KLPYNGMVDCFAKVAKQEGVFRFYRGFGTYYVRIAPHAMVTLLVADYLGWLTK 331
Score = 55 bits (132), Expect = 8e-007
Identities = 29/42 (69%), Positives = 32/42 (76%), Gaps = 1/42 (2%)
Frame = +2
Query: 179 PFVNGGTSGMLATCVIQPIDMIKVRIQL-GQGSAASVTSTML 301
PF+NGG SGM+AT VIQPIDMIKVRIQL G+G A T L
Sbjct: 44 PFINGGLSGMVATTVIQPIDMIKVRIQLAGEGKAGGPKPTPL 85
>sp|Q9UBX3|DIC_HUMAN Mitochondrial dicarboxylate carrier OS=Homo sapiens
GN=SLC25A10 PE=1 SV=2
Length = 287
Score = 168 bits (424), Expect = 1e-040
Identities = 101/280 (36%), Positives = 147/280 (52%), Gaps = 22/280 (7%)
Frame = +2
Query: 191 GGTSGMLATCVIQPIDMIKVRIQLGQGSAASVTSTML---KNEGIGAFYKGLSAGLLRQA 361
GG + A C P+D++KV +Q Q +T L + +GI A Y GLSA L RQ
Sbjct: 13 GGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQM 72
Query: 362 TYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLALIRMQADN 541
TY+ R ++ + + ++ + G PLP ++K L G +G G VG+PADL +RMQ D
Sbjct: 73 TYSLTRFAIYETVRDRVAKGSQG-PLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDV 131
Query: 542 TLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLASYDQ------S 703
LP QRRNY +A LYR++ +EG+ L+ G R + +G L+ YDQ S
Sbjct: 132 KLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLS 191
Query: 704 AEYMRDNLGLGETSTVVGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPYTGSLDC 883
Y+ DN+ T AS ++G CA P D +KT++ K Y G C
Sbjct: 192 TGYLSDNI-----FTHFVASFIAGGCATFLCQPLDVLKTRLM------NSKGEYQGVFHC 240
Query: 884 AMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITK 1003
A++T K GPL FY G +R+ PH ++T++FL Q+ K
Sbjct: 241 AVETAKL-GPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRK 279
>sp|Q9QZD8|DIC_MOUSE Mitochondrial dicarboxylate carrier OS=Mus musculus
GN=Slc25a10 PE=2 SV=2
Length = 287
Score = 158 bits (397), Expect = 1e-037
Identities = 98/280 (35%), Positives = 144/280 (51%), Gaps = 22/280 (7%)
Frame = +2
Query: 191 GGTSGMLATCVIQPIDMIKVRIQLGQGSAASVTSTML---KNEGIGAFYKGLSAGLLRQA 361
GG + A C P+D++KV +Q Q +T L + +G A Y GLSA L RQ
Sbjct: 12 GGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQM 71
Query: 362 TYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLALIRMQADN 541
TY+ R ++ + ++ + G PLP Y K L G +G G VG+PADL +RMQ D
Sbjct: 72 TYSLTRFAIYETMRDYMTKDSQG-PLPFYNKVLLGGISGLTGGFVGTPADLVNVRMQNDM 130
Query: 542 TLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLASYDQ------S 703
LP +QRRNY++A LYR++ +E + L+ G R + +G L+ YDQ S
Sbjct: 131 KLPPSQRRNYSHALDGLYRVAREESLRKLFSGATMASSRGALVTVGQLSCYDQAKQLVLS 190
Query: 704 AEYMRDNLGLGETSTVVGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPYTGSLDC 883
Y+ DN+ T +S ++G CA P D +KT++ K Y G C
Sbjct: 191 TGYLSDNI-----FTHFVSSFIAGGCATFLCQPLDVLKTRLM------NSKGEYQGVFHC 239
Query: 884 AMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITK 1003
AM+T K GP F+ G +R+ PH ++T++FL Q+ K
Sbjct: 240 AMETAKL-GPQAFFKGLFPAGIRLIPHTVLTFMFLEQLRK 278
>sp|Q6FTN2|DIC1_CANGA Mitochondrial dicarboxylate transporter OS=Candida
glabrata GN=DIC1 PE=3 SV=1
Length = 295
Score = 141 bits (353), Expect = 2e-032
Identities = 92/288 (31%), Positives = 148/288 (51%), Gaps = 12/288 (4%)
Frame = +2
Query: 179 PFVNGGTSGMLATCVIQPIDMIKVRIQ---LGQGSAASVTSTMLKNEGIGAFYKGLSAGL 349
P+ GG +G+ A P+D+ KVR+Q + + + + ++LKNEGI Y GLSA L
Sbjct: 9 PWWYGGAAGIFAVMNTHPLDLTKVRLQAAPIPKPTIVQMLRSILKNEGIVGLYAGLSASL 68
Query: 350 LRQATYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLALIRM 529
LRQ TYTTAR G + L K K ++ + +GA+G G+ ADL IRM
Sbjct: 69 LRQCTYTTARFGMYDAL--KEHVIPRDKLTNMWYLLGASMVSGALGGLAGNFADLINIRM 126
Query: 530 QADNTLPLAQRRNYTNAFHALYRISADEGVLALW-KGCGPTVVRAMALNMGMLASYDQSA 706
Q D+ LPL +RRNY NA + +I EG +L+ G P +VR + + + +YD
Sbjct: 127 QNDSALPLDKRRNYKNAIDGMVKIYKAEGAKSLFLTGWKPNMVRGVLMTASQVVTYDMFK 186
Query: 707 EYM--RDNLGLGETSTVVGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGKYPYTGSLD 880
++ + N+ + ST + +S ++GF A P D +KT + M + + + S
Sbjct: 187 NFLVTKYNMDPKKNSTHLTSSLLAGFVATTVCSPADVIKTIV--MNAHKKPGHNHDSSFK 244
Query: 881 CAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITKFQKTIGM 1024
M+ + GP + G+ R+AP M+ + + Q+ K++ +GM
Sbjct: 245 ILMEAINKEGPSFMFRGWVPSFTRLAPFTMLIFFAMEQLKKYR--VGM 290
>sp|Q06143|DIC1_YEAST Mitochondrial dicarboxylate transporter OS=Saccharomyces
cerevisiae GN=DIC1 PE=1 SV=1
Length = 298
Score = 134 bits (337), Expect = 1e-030
Identities = 94/296 (31%), Positives = 145/296 (48%), Gaps = 24/296 (8%)
Frame = +2
Query: 167 NTVKPFVNGGTSGMLATCVIQPIDMIKVRIQ---LGQGSAASVTSTMLKNEGIGAFYKGL 337
N P+ GG +G+ AT V P+D+ KVR+Q + + + + ++L NEG+ Y GL
Sbjct: 12 NIKYPWWYGGAAGIFATMVTHPLDLAKVRLQAAPMPKPTLFRMLESILANEGVVGLYSGL 71
Query: 338 SAGLLRQATYTTARLGSFKML----TAKASEANDGKPLPLYQKALCGLTAGAIGACVGSP 505
SA +LRQ TYTT R G++ +L + N LP C + +GAIG G+
Sbjct: 72 SAAVLRQCTYTTVRFGAYDLLKENVIPREQLTNMAYLLP------CSMFSGAIGGLAGNF 125
Query: 506 ADLALIRMQADNTLPLAQRRNYTNAFHALYRISADEGVL-ALWKGCGPTVVRAMALNMGM 682
AD+ IRMQ D+ L A+RRNY NA +Y+I EG L L+ G P +VR + +
Sbjct: 126 ADVVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRYEGGLKTLFTGWKPNMVRGILMTASQ 185
Query: 683 LASYDQSAEYMRDNLGL--GETSTVVGASAVSGFCAAACSLPFDFVKTQIQKMQPDAQGK 856
+ +YD Y+ L + T + AS ++G A P D +KT+I D Q
Sbjct: 186 VVTYDVFKNYLVTKLDFDASKNYTHLTASLLAGLVATTVCSPADVMKTRIMNGSGDHQ-- 243
Query: 857 YPYTGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQITKFQKTIGM 1024
+L ++ GP + G+ R+ P M+ + + Q+ K + +GM
Sbjct: 244 ----PALKILADAVRKEGPSFMFRGWLPSFTRLGPFTMLIFFAIEQLKKHR--VGM 293
>sp|B0G143|UCPB_DICDI Mitochondrial substrate carrier family protein ucpB
OS=Dictyostelium discoideum GN=ucpB PE=3 SV=1
Length = 294
Score = 117 bits (292), Expect = 2e-025
Identities = 73/188 (38%), Positives = 102/188 (54%), Gaps = 14/188 (7%)
Frame = +2
Query: 182 FVNGGTSGMLATCVIQPIDMIKVRIQL-GQG------SAASVTSTMLKNEGIGAFYKGLS 340
F+ GG S M A V P+D++K R Q+ G+G + T ++KNEGI A YKGL+
Sbjct: 11 FLFGGLSCMGAAVVSNPVDVLKTRFQIHGEGIDSKSLGLVNGTIKIIKNEGISAMYKGLT 70
Query: 341 AGLLRQATYTTARLGSFKMLTAKASEANDGKPLPLYQKALCGLTAGAIGACVGSPADLAL 520
LLR+ATY+T R+G + ++ ++N GK L K G +GA+GAC+ SP DL
Sbjct: 71 PSLLREATYSTLRMGGYDVIKNYFIDSN-GK-TNLLSKVTSGALSGALGACITSPTDLIK 128
Query: 521 IRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGCGPTVVRAMALNMGMLASYDQ 700
+RMQA ++ Y + A I A EG+ LWKG GPT RA L + SYD
Sbjct: 129 VRMQAS-----SKGVKYDSISSAFKEIIAKEGIKGLWKGVGPTTQRAALLTASQIPSYDH 183
Query: 701 SAEYMRDN 724
+ D+
Sbjct: 184 IKHMILDH 191
>sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 OS=Bos taurus GN=UCP3
PE=2 SV=1
Length = 311
Score = 109 bits (270), Expect = 8e-023
Identities = 72/242 (29%), Positives = 110/242 (45%), Gaps = 15/242 (6%)
Frame = +2
Query: 293 TMLKNEGIGAFYKGLSAGLLRQATYTTARLGSF----KMLTAKASEANDGKPLPLYQKAL 460
TM++ EG + Y GL AGL RQ ++ + R+G + + T K S+ + + + L
Sbjct: 67 TMVRTEGPRSLYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS-----IITRIL 121
Query: 461 CGLTAGAIGACVGSPADLALIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGC 640
G T GA+ P D+ IR QA L R Y+ A I+ +EGV LWKG
Sbjct: 122 AGCTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGI 181
Query: 641 GPTVVRAMALNMGMLASYDQSAEYMRDNLGLGETSTVVGASAV-SGFCAAACSLPFDFVK 817
P + R +N G + +YD E + D L + SA +GFCA + P D VK
Sbjct: 182 LPNITRNAIVNCGEMVTYDIIKEKLLDYHLLTDNFPCHFVSAFGAGFCATLVASPVDVVK 241
Query: 818 TQIQKMQPDAQGKYPYTGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQI 997
T+ P Y DC ++ + GP FY GF +R+ ++ ++ Q+
Sbjct: 242 TRYMNSPPG-----QYHSPFDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQM 296
Query: 998 TK 1003
+
Sbjct: 297 KR 298
>sp|Q9N2I9|UCP3_CANFA Mitochondrial uncoupling protein 3 OS=Canis familiaris
GN=UCP3 PE=2 SV=1
Length = 311
Score = 106 bits (264), Expect = 4e-022
Identities = 71/242 (29%), Positives = 110/242 (45%), Gaps = 15/242 (6%)
Frame = +2
Query: 293 TMLKNEGIGAFYKGLSAGLLRQATYTTARLGSF----KMLTAKASEANDGKPLPLYQKAL 460
TM++ EG + Y GL AGL RQ ++ + R+G + + T K S+ + + + L
Sbjct: 67 TMVRTEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS-----ITTRIL 121
Query: 461 CGLTAGAIGACVGSPADLALIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGC 640
G T GA+ P D+ +R QA L R Y+ A I+ +EGV LWKG
Sbjct: 122 AGCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGT 181
Query: 641 GPTVVRAMALNMGMLASYDQSAEYMRDNLGLGETSTVVGASAV-SGFCAAACSLPFDFVK 817
P + R +N + +YD E + D L + SA +GFCA + P D VK
Sbjct: 182 LPNITRNAIVNCAEMVTYDIIKEKLLDYHLLTDNFPCHLISAFGAGFCATVVASPVDVVK 241
Query: 818 TQIQKMQPDAQGKYPYTGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQI 997
T+ P Y LDC ++ + GP FY GF +R+ ++ ++ Q+
Sbjct: 242 TRYMNSPPG-----QYCSPLDCMLKMVTQEGPTAFYKGFTPSFLRLGTWNVVMFVTYEQL 296
Query: 998 TK 1003
+
Sbjct: 297 KR 298
>sp|P56499|UCP3_RAT Mitochondrial uncoupling protein 3 OS=Rattus norvegicus
GN=Ucp3 PE=2 SV=1
Length = 308
Score = 101 bits (250), Expect = 2e-020
Identities = 69/242 (28%), Positives = 108/242 (44%), Gaps = 15/242 (6%)
Frame = +2
Query: 293 TMLKNEGIGAFYKGLSAGLLRQATYTTARLGSF----KMLTAKASEANDGKPLPLYQKAL 460
TM++ EG + Y GL AGL RQ ++ + R+G + + T K ++ + + + L
Sbjct: 64 TMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDHSS-----VAIRIL 118
Query: 461 CGLTAGAIGACVGSPADLALIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGC 640
G T GA+ P D+ +R QA L R Y A I+ +EGV LWKG
Sbjct: 119 AGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGT 178
Query: 641 GPTVVRAMALNMGMLASYDQSAEYMRDNLGLGETSTVVGASAV-SGFCAAACSLPFDFVK 817
P + R +N + +YD E + D+ + SA +GFCA + P D VK
Sbjct: 179 WPNITRNAIVNCAEMVTYDIIKEKLLDSHLFTDNFPCHFVSAFGAGFCATVVASPVDVVK 238
Query: 818 TQIQKMQPDAQGKYPYTGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQI 997
T+ P Y L C ++ + GP FY GF +R+ +M ++ Q+
Sbjct: 239 TRYMNAPPGR-----YRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQL 293
Query: 998 TK 1003
+
Sbjct: 294 KR 295
>sp|P32332|OAC1_YEAST Mitochondrial oxaloacetate transport protein
OS=Saccharomyces cerevisiae GN=OAC1 PE=1 SV=1
Length = 324
Score = 99 bits (244), Expect = 8e-020
Identities = 69/250 (27%), Positives = 119/250 (47%), Gaps = 12/250 (4%)
Frame = +2
Query: 290 STMLKNEGIGAFYKGLSAGLLRQATYTTARLGSFKMLTAKASEA--NDGKPLPLYQ---K 454
+ + KNEGI KGL+A + Q +RLG ++ + + ++ D +P +
Sbjct: 72 AVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHKVQSVGVN 131
Query: 455 ALCGLTAGAIGACVGSPADLALIRMQA-DNTLPLAQRRNYTNAFHALYRISADEGVLALW 631
G +G IGA +GSP L R+Q+ + + ++ +YT ++ L I EGV L+
Sbjct: 132 VFSGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKTEGVKGLF 191
Query: 632 KGCGPTVVRAMALNMGMLASYDQSAEYM-RDNLGLGETSTVVGASAVSGFCAAACSLPFD 808
+G ++R A + L Y+ + + +++L + + AS +SG A P+D
Sbjct: 192 RGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMKDGPALHLTASTISGLGVAVVMNPWD 251
Query: 809 FVKTQIQKMQPDAQGKYPYTGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFL 988
+ T+I + D Y G +DC ++T++ G Y GF RIAPH +M F+
Sbjct: 252 VILTRIYNQKGDL-----YKGPIDCLVKTVRIEGVTALYKGFAAQVFRIAPHTIMCLTFM 306
Query: 989 NQITKFQKTI 1018
Q K +I
Sbjct: 307 EQTMKLVYSI 316
>sp|P56501|UCP3_MOUSE Mitochondrial uncoupling protein 3 OS=Mus musculus GN=Ucp3
PE=2 SV=1
Length = 308
Score = 96 bits (236), Expect = 7e-019
Identities = 67/242 (27%), Positives = 107/242 (44%), Gaps = 15/242 (6%)
Frame = +2
Query: 293 TMLKNEGIGAFYKGLSAGLLRQATYTTARLGSF----KMLTAKASEANDGKPLPLYQKAL 460
TM++ EG + Y GL AGL RQ ++ + R+G + + T K ++ + + + L
Sbjct: 64 TMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGADHSS-----VAIRIL 118
Query: 461 CGLTAGAIGACVGSPADLALIRMQADNTLPLAQRRNYTNAFHALYRISADEGVLALWKGC 640
G T GA+ P D+ +R QA L R Y A I+ +EGV LWKG
Sbjct: 119 AGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGT 178
Query: 641 GPTVVRAMALNMGMLASYDQSAEYMRDNLGLGETSTVVGASAV-SGFCAAACSLPFDFVK 817
P + R +N + +YD E + ++ + SA +GFCA + P D VK
Sbjct: 179 WPNITRNAIVNCAEMVTYDIIKEKLLESHLFTDNFPCHFVSAFGAGFCATVVASPVDVVK 238
Query: 818 TQIQKMQPDAQGKYPYTGSLDCAMQTLKSGGPLKFYTGFPVYCVRIAPHVMMTWIFLNQI 997
T+ Y L C ++ + GP FY GF +R+ +M ++ Q+
Sbjct: 239 TRYMNAPLGR-----YRSPLHCMLKMVAQEGPTAFYKGFVPSFLRLGAWNVMMFVTYEQL 293
Query: 998 TK 1003
+
Sbjct: 294 KR 295
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,892,683,958
Number of Sequences: 518415
Number of Extensions: 92892683958
Number of Successful Extensions: 611291351
Number of sequences better than 0.0: 0
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