BLASTX 7.6.2
Query= UN22533 /QuerySize=1356
(1355 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P00561|AK1H_ECOLI Bifunctional aspartokinase/homoserine dehyd... 183 3e-045
sp|P27725|AK1H_SERMA Bifunctional aspartokinase/homoserine dehyd... 183 3e-045
sp|P49079|AKH1_MAIZE Bifunctional aspartokinase/homoserine dehyd... 183 3e-045
sp|P49080|AKH2_MAIZE Bifunctional aspartokinase/homoserine dehyd... 182 7e-045
sp|P44505|AKH_HAEIN Bifunctional aspartokinase/homoserine dehydr... 179 4e-044
sp|Q89AR4|AKH_BUCBP Bifunctional aspartokinase/homoserine dehydr... 179 6e-044
sp|P37142|AKH_DAUCA Bifunctional aspartokinase/homoserine dehydr... 178 8e-044
sp|O81852|AKH2_ARATH Bifunctional aspartokinase/homoserine dehyd... 176 3e-043
sp|Q9SA18|AKH1_ARATH Bifunctional aspartokinase/homoserine dehyd... 175 9e-043
sp|Q8K9U9|AKH_BUCAP Bifunctional aspartokinase/homoserine dehydr... 173 3e-042
sp|P31116|DHOM_YEAST Homoserine dehydrogenase OS=Saccharomyces c... 172 8e-042
sp|P57290|AKH_BUCAI Bifunctional aspartokinase/homoserine dehydr... 170 3e-041
sp|P00562|AK2H_ECOLI Bifunctional aspartokinase/homoserine dehyd... 166 3e-040
sp|Q5B998|DHOM_EMENI Homoserine dehydrogenase OS=Emericella nidu... 160 2e-038
sp|O94671|DHOM_SCHPO Probable homoserine dehydrogenase OS=Schizo... 142 7e-033
>sp|P00561|AK1H_ECOLI Bifunctional aspartokinase/homoserine dehydrogenase 1
OS=Escherichia coli (strain K12) GN=thrA PE=1 SV=2
Length = 820
Score = 183 bits (464), Expect = 3e-045
Identities = 108/264 (40%), Positives = 159/264 (60%), Gaps = 7/264 (2%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL----VLDPRRIRHESTV 583
V+VDC++S + + G VV NKK TS++++Y +L R+ +++ V
Sbjct: 550 VIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNV 609
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLPVI ++ ++++GD + G LSG+L Y+ +L++G S A+ +GYTEPD
Sbjct: 610 GAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPD 669
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDLSGMDVARK LILAR G+ + + I+IE + P E V F+ N +++LD
Sbjct: 670 PRDDLSGMDVARKLLILARETGRELELADIEIEPVLPAEFN-AEGDVAAFMAN-LSQLDD 727
Query: 944 SIEERVKRASSNGCVLRYVCVIEGSSV-QVGIREVPKDSPLGRLRGSDNIVEIRSRCYKE 1120
RV +A G VLRYV I+ V +V I EV + PL +++ +N + S Y+
Sbjct: 728 LFAARVAKARDEGKVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQP 787
Query: 1121 QPLVIQGAGAGNDTTAAGVFADII 1192
PLV++G GAGND TAAGVFAD++
Sbjct: 788 LPLVLRGYGAGNDVTAAGVFADLL 811
>sp|P27725|AK1H_SERMA Bifunctional aspartokinase/homoserine dehydrogenase 1
OS=Serratia marcescens GN=thrA PE=3 SV=1
Length = 819
Score = 183 bits (464), Expect = 3e-045
Identities = 105/263 (39%), Positives = 157/263 (59%), Gaps = 6/263 (2%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL----VLDPRRIRHESTV 583
V+VDC++S + + + G VV NKK TS++ +Y +L R+ +++ V
Sbjct: 550 VIVDCTSSQAVADQYVDFLADGFHVVTPNKKANTSSMNYYQQLRAAAAGSHRKFLYDTNV 609
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLPVI ++ ++++GD + G LSG+L ++ +L++G LS A+ GYTEPD
Sbjct: 610 GAGLPVIENLQNLLNAGDELVRFSGILSGSLSFIFGKLDEGLSLSAATLQARANGYTEPD 669
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDLSGMDVARK LILAR G ++ + I++E + P VD FL + +LD+
Sbjct: 670 PRDDLSGMDVARKLLILAREAGYKLELSDIEVEPVLPPSF-DASGDVDTFLAR-LPELDK 727
Query: 944 SIEERVKRASSNGCVLRYVCVIEGSSVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYKEQ 1123
V A+ G VLRYV +I+ +V I V + PL +++ +N + SR Y+
Sbjct: 728 EFARNVANAAEQGKVLRYVGLIDEGRCKVRIEAVDGNDPLYKVKNGENALAFYSRYYQPL 787
Query: 1124 PLVIQGAGAGNDTTAAGVFADII 1192
PLV++G GAGND TAAGVFAD++
Sbjct: 788 PLVLRGYGAGNDVTAAGVFADLL 810
>sp|P49079|AKH1_MAIZE Bifunctional aspartokinase/homoserine dehydrogenase 1,
chloroplastic OS=Zea mays GN=AKHSDH1 PE=2 SV=1
Length = 920
Score = 183 bits (464), Expect = 3e-045
Identities = 108/265 (40%), Positives = 152/265 (57%), Gaps = 8/265 (3%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL-VLDPRRIRH---ESTV 583
V+VDC+A + + G V+ NKK + L+ Y KL L H E+TV
Sbjct: 648 VLVDCTADTSVASHYYDWLKKGIHVITPNKKANSGPLDRYLKLRTLQRASYTHYFYEATV 707
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLP+I+++ ++ +GD + I G SGTL Y+ + E R S VV AK GYTEPD
Sbjct: 708 GAGLPIISTLRGLLETGDKILRIEGIFSGTLSYIFNNFEGARTFSDVVAEAKKAGYTEPD 767
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDLSG DVARK +ILAR G + + I + SL PE ++ + D+++Q + D+
Sbjct: 768 PRDDLSGTDVARKVIILARESGLGLELSDIPVRSLVPEALK-SCTSADEYMQK-LPSFDE 825
Query: 944 SIEERVKRASSNGCVLRYVCVIE--GSSVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYK 1117
K A + G VLRYV V++ QV +R +D P +L GSDNI+ + YK
Sbjct: 826 DWARERKNAEAAGEVLRYVGVVDVVSKKGQVELRAYKRDHPFAQLSGSDNIIAFTTSRYK 885
Query: 1118 EQPLVIQGAGAGNDTTAAGVFADII 1192
+QPL+++G GAG + TA GVF DI+
Sbjct: 886 DQPLIVRGPGAGAEVTAGGVFCDIL 910
>sp|P49080|AKH2_MAIZE Bifunctional aspartokinase/homoserine dehydrogenase 2,
chloroplastic OS=Zea mays GN=AKHSDH2 PE=2 SV=1
Length = 917
Score = 182 bits (460), Expect = 7e-045
Identities = 107/265 (40%), Positives = 153/265 (57%), Gaps = 8/265 (3%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKLVLDPR----RIRHESTV 583
V+VDC+A + + G V+ NKK + L+ Y KL R +E+TV
Sbjct: 645 VLVDCTADTSVASHYYDWLKKGIHVITPNKKANSGPLDQYLKLRTMQRASYTHYFYEATV 704
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLP+I+++ ++ +GD + I G SGTL Y+ + E R S VV A+ GYTEPD
Sbjct: 705 GAGLPIISTLRGLLETGDKILRIEGIFSGTLSYIFNNFEGTRAFSDVVAEAREAGYTEPD 764
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDLSG DVARK ++LAR G R+ + I ++SL PE + + D+F+Q + D+
Sbjct: 765 PRDDLSGTDVARKVVVLARESGLRLELSDIPVKSLVPETL-ASCSSADEFMQK-LPSFDE 822
Query: 944 SIEERVKRASSNGCVLRYVCVIE--GSSVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYK 1117
+ A + G VLRYV ++ S QV +R +D P +L GSDNI+ + YK
Sbjct: 823 DWARQRSDAEAAGEVLRYVGALDAVNRSGQVELRRYRRDHPFAQLSGSDNIIAFTTSRYK 882
Query: 1118 EQPLVIQGAGAGNDTTAAGVFADII 1192
EQPL+++G GAG + TA GVF DI+
Sbjct: 883 EQPLIVRGPGAGAEVTAGGVFCDIL 907
>sp|P44505|AKH_HAEIN Bifunctional aspartokinase/homoserine dehydrogenase
OS=Haemophilus influenzae GN=thrA PE=3 SV=1
Length = 815
Score = 179 bits (454), Expect = 4e-044
Identities = 102/263 (38%), Positives = 159/263 (60%), Gaps = 6/263 (2%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKLVLDPRRIRH----ESTV 583
V VDC+++ + +A+ G VV NKK T L +Y++L + + +H E+ V
Sbjct: 550 VFVDCTSAESVAGLYARALKEGFHVVTPNKKANTRELVYYNELRQNAQASQHKFLYETNV 609
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLPVI ++ ++++GD + G LSG+L ++ +LE+G LS V A+ G+TEPD
Sbjct: 610 GAGLPVIENLQNLLAAGDELEYFEGILSGSLSFIFGKLEEGLSLSEVTALAREKGFTEPD 669
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDLSG DVARK LILAR G + + +++E + P+ G + D+F+ + +LD+
Sbjct: 670 PRDDLSGQDVARKLLILAREAGIELELSDVEVEGVLPKGFSDG-KSADEFMAM-LPQLDE 727
Query: 944 SIEERVKRASSNGCVLRYVCVIEGSSVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYKEQ 1123
+ RV A + G VLRYV I +V I V ++PL +++ +N + +R Y+
Sbjct: 728 EFKTRVATAKAEGKVLRYVGKISEGKCKVSIVAVDLNNPLYKVKDGENALAFYTRYYQPI 787
Query: 1124 PLVIQGAGAGNDTTAAGVFADII 1192
PL+++G GAGN TAAG+FADI+
Sbjct: 788 PLLLRGYGAGNAVTAAGIFADIL 810
>sp|Q89AR4|AKH_BUCBP Bifunctional aspartokinase/homoserine dehydrogenase
OS=Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) GN=thrA
PE=3 SV=1
Length = 816
Score = 179 bits (452), Expect = 6e-044
Identities = 99/264 (37%), Positives = 163/264 (61%), Gaps = 7/264 (2%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKLVL----DPRRIRHESTV 583
++VDC++ + ++ G +V NKK T+ ++Y+ + L + ++ +E+ V
Sbjct: 551 IIVDCTSDKNIANQYISFINCGFHIVTPNKKANTTNWKYYEDIRLAAQKEKKKFFYETNV 610
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLPVI ++ ++ +GD + G LSG+L ++ +LED LS + A++LG+TEP+
Sbjct: 611 GAGLPVIENLKNLLRTGDTLIHFKGILSGSLSFIFGKLEDNISLSEATKQAQSLGFTEPN 670
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
P+DDLSG+DVARK LILAR +G ++ + IKIE L P+E + DF+ + +LDQ
Sbjct: 671 PKDDLSGIDVARKLLILAREVGYKLELKDIKIEPLLPKEFN-NISNTTDFITK-LKELDQ 728
Query: 944 SIEERVKRASSNGCVLRYVCVI-EGSSVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYKE 1120
RVK+A G LR+V +I + + QV I EV + PL ++ +N + S+ Y+
Sbjct: 729 IFCNRVKKARKLGKRLRFVGIINQKGNCQVKIDEVDHNDPLYNIKNGENALAFYSKYYQP 788
Query: 1121 QPLVIQGAGAGNDTTAAGVFADII 1192
PLV++G GAGN+ TA+G+F+D++
Sbjct: 789 IPLVLRGYGAGNNVTASGIFSDVL 812
>sp|P37142|AKH_DAUCA Bifunctional aspartokinase/homoserine dehydrogenase,
chloroplastic (Fragment) OS=Daucus carota PE=1 SV=1
Length = 921
Score = 178 bits (451), Expect = 8e-044
Identities = 106/265 (40%), Positives = 156/265 (58%), Gaps = 8/265 (3%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL-VLDPRRIRH---ESTV 583
V+VDC+A SE + G V+ NKK + L+ Y KL L R H E+TV
Sbjct: 649 VIVDCTADSEVASHYHDWLCRGIHVITPNKKANSGPLDQYLKLRALQRRSYTHYFYEATV 708
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
AGLP+I ++ ++ +GD + I G SGTL Y+ + + P S VV AK GYTEPD
Sbjct: 709 VAGLPIITTLQGLLETGDKILRIEGIFSGTLSYIFNNFKSTTPFSEVVSEAKAAGYTEPD 768
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDL+G DVARK +ILAR G ++ + I ++SL PE +R G+ + ++FL + + D
Sbjct: 769 PRDDLAGTDVARKVIILARGSGLKLELSDIPVQSLVPEPLR-GIASAEEFLLQ-LPQFDS 826
Query: 944 SIEERVKRASSNGCVLRYVCVIEGSSVQ--VGIREVPKDSPLGRLRGSDNIVEIRSRCYK 1117
+ + + A + G VLRYV V++ + + V ++ K+ P +L GSDNI + Y
Sbjct: 827 DMTRKREDAENAGEVLRYVGVVDAVNQKGVVELKRYKKEHPFAQLSGSDNINAFTTERYN 886
Query: 1118 EQPLVIQGAGAGNDTTAAGVFADII 1192
+QP +I+G GAG + TA GVF+DI+
Sbjct: 887 KQPPIIRGPGAGAEVTAGGVFSDIL 911
>sp|O81852|AKH2_ARATH Bifunctional aspartokinase/homoserine dehydrogenase 2,
chloroplastic OS=Arabidopsis thaliana GN=AKHSDH2 PE=1 SV=1
Length = 916
Score = 176 bits (446), Expect = 3e-043
Identities = 105/265 (39%), Positives = 157/265 (59%), Gaps = 8/265 (3%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL-VLDPRRIRH---ESTV 583
VVVDC+A S + G V+ NKK + L+ Y KL L + H E+TV
Sbjct: 644 VVVDCTADSAIASRYYDWLRKGIHVITPNKKANSGPLDQYLKLRDLQRKSYTHYFYEATV 703
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLP+I+++ ++ +GD + I G SGTL Y+ + R S VV AK G+TEPD
Sbjct: 704 GAGLPIISTLRGLLETGDKILRIEGICSGTLSYLFNNFVGDRSFSEVVTEAKNAGFTEPD 763
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDLSG DVARK +ILAR G ++ + + I SL PE ++ G +V++F++ + + D
Sbjct: 764 PRDDLSGTDVARKVIILARESGLKLDLADLPIRSLVPEPLK-GCTSVEEFMEK-LPQYDG 821
Query: 944 SIEERVKRASSNGCVLRYVCVIEGSSVQ--VGIREVPKDSPLGRLRGSDNIVEIRSRCYK 1117
+ + A ++G VLRYV V++ + + V +R K+ P +L GSDNI+ + YK
Sbjct: 822 DLAKERLDAENSGEVLRYVGVVDAVNQKGTVELRRYKKEHPFAQLAGSDNIIAFTTTRYK 881
Query: 1118 EQPLVIQGAGAGNDTTAAGVFADII 1192
+ PL+++G GAG TA G+F+DI+
Sbjct: 882 DHPLIVRGPGAGAQVTAGGIFSDIL 906
>sp|Q9SA18|AKH1_ARATH Bifunctional aspartokinase/homoserine dehydrogenase 1,
chloroplastic OS=Arabidopsis thaliana GN=AKHSDH1 PE=1 SV=1
Length = 911
Score = 175 bits (442), Expect = 9e-043
Identities = 99/265 (37%), Positives = 160/265 (60%), Gaps = 8/265 (3%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL-VLDPRRIRH---ESTV 583
V+VDC+A ++ + G VV NKK + L+ Y K+ L + H E+TV
Sbjct: 639 VMVDCTADADIASCYYDWLLRGIHVVTPNKKANSGPLDQYLKIRDLQRKSYTHYFYEATV 698
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLP+I+++ ++ +GD + I G SGTL Y+ + R S VV AK G+TEPD
Sbjct: 699 GAGLPIISTLRGLLETGDKILRIEGIFSGTLSYLFNNFVGTRSFSEVVAEAKQAGFTEPD 758
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
PRDDLSG DVARK ILAR G ++ ++ + +++L P+ ++ + ++F++ + + D+
Sbjct: 759 PRDDLSGTDVARKVTILARESGLKLDLEGLPVQNLVPKPLQ-ACASAEEFMEK-LPQFDE 816
Query: 944 SIEERVKRASSNGCVLRYVCVIEGSSVQ--VGIREVPKDSPLGRLRGSDNIVEIRSRCYK 1117
+ ++ + A + G VLRYV V++ + V ++ KD P +L G+DNI+ ++ YK
Sbjct: 817 ELSKQREEAEAAGEVLRYVGVVDAVEKKGTVELKRYKKDHPFAQLSGADNIIAFTTKRYK 876
Query: 1118 EQPLVIQGAGAGNDTTAAGVFADII 1192
EQPL+++G GAG TA G+F+DI+
Sbjct: 877 EQPLIVRGPGAGAQVTAGGIFSDIL 901
>sp|Q8K9U9|AKH_BUCAP Bifunctional aspartokinase/homoserine dehydrogenase
OS=Buchnera aphidicola subsp. Schizaphis graminum GN=thrA PE=3 SV=1
Length = 814
Score = 173 bits (437), Expect = 3e-042
Identities = 98/264 (37%), Positives = 161/264 (60%), Gaps = 7/264 (2%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL----VLDPRRIRHESTV 583
V++DC++ + + + G ++ +NKK T +L++Y ++ + + ++ +E+ V
Sbjct: 549 VIIDCTSDYILSKQYISFIKKGFHIITSNKKANTDSLKYYSEIRTTALKENKKFLYETNV 608
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLPVI ++ + S+GD + S G LSG+L ++ +LE+G LS + AK LG+TEP+
Sbjct: 609 GAGLPVINTLQSLFSTGDCLISFKGILSGSLSFIFGKLEEGVLLSEATKEAKKLGFTEPN 668
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
P DDLSG+DVARK L+LAR +G I + I IE + PE + ++FL + +LD
Sbjct: 669 PFDDLSGIDVARKLLVLAREIGYSIELKDISIEPILPERFKK-YQNSEEFLFK-LKELDS 726
Query: 944 SIEERVKRASSNGCVLRYVCVIE-GSSVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYKE 1120
ERV +A G VLR++ IE V I E+ ++PL +++ +N + + Y+
Sbjct: 727 FFSERVNKARDIGNVLRFIGSIEKNGKCSVKIEEINSNNPLYKVKNGENALTFYTNYYQP 786
Query: 1121 QPLVIQGAGAGNDTTAAGVFADII 1192
PLV++G GAGND TA+GVF+D++
Sbjct: 787 IPLVLRGYGAGNDVTASGVFSDLL 810
>sp|P31116|DHOM_YEAST Homoserine dehydrogenase OS=Saccharomyces cerevisiae
GN=HOM6 PE=1 SV=1
Length = 359
Score = 172 bits (434), Expect = 8e-042
Identities = 106/282 (37%), Positives = 161/282 (57%), Gaps = 13/282 (4%)
Frame = +2
Query: 377 EAVAQLLGKSAGLVVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKLVLDP 556
+ +A L +++VD ++S+ K V+ G + NKK +S L + L +
Sbjct: 75 DLIAHLKTSPKPVILVDNTSSAYIAGFYTKFVENGISIATPNKKAFSSDLATWKALFSNK 134
Query: 557 RR---IRHESTVGAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGR----PL 715
+ HE+TVGAGLP+I+ + II +GD V I G SGTL Y+ +E +
Sbjct: 135 PTNGFVYHEATVGAGLPIISFLREIIQTGDEVEKIEGIFSGTLSYIFNEFSTSQANDVKF 194
Query: 716 SLVVRAAKTLGYTEPDPRDDLSGMDVARKGLILARLLGKRI-IMDSIKIESLYPEEMRPG 892
S VV+ AK LGYTEPDPRDDL+G+DVARK I+ R+ G + S ++SL P+ +
Sbjct: 195 SDVVKVAKKLGYTEPDPRDDLNGLDVARKVTIVGRISGVEVESPTSFPVQSLIPKPLE-S 253
Query: 893 VMTVDDFLQNGIAKLDQSIEERVKRASSNGCVLRYVCVIE--GSSVQVGIREVPKDSPLG 1066
V + D+FL+ ++ D+ + + K A++ VLR++ ++ SV VGI + P
Sbjct: 254 VKSADEFLEK-LSDYDKDLTQLKKEAATENKVLRFIGKVDVATKSVSVGIEKYDYSHPFA 312
Query: 1067 RLRGSDNIVEIRSRCYKEQPLVIQGAGAGNDTTAAGVFADII 1192
L+GSDN++ I+++ Y P+VIQGAGAG TAAGV D+I
Sbjct: 313 SLKGSDNVISIKTKRY-TNPVVIQGAGAGAAVTAAGVLGDVI 353
>sp|P57290|AKH_BUCAI Bifunctional aspartokinase/homoserine dehydrogenase
OS=Buchnera aphidicola subsp. Acyrthosiphon pisum GN=thrA PE=3 SV=1
Length = 816
Score = 170 bits (429), Expect = 3e-041
Identities = 105/264 (39%), Positives = 155/264 (58%), Gaps = 7/264 (2%)
Frame = +2
Query: 416 VVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHYDKL----VLDPRRIRHESTV 583
V+VDC++S E + +D VV +NKK TS +Y K+ ++ +E+ V
Sbjct: 551 VIVDCTSSQLLSEQYVNFIDNNFHVVTSNKKANTSEWNYYKKIRKSVAQTGKKFLYETNV 610
Query: 584 GAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEPD 763
GAGLPVI ++ + SGD + G LSG+L ++ LE+G LS R AK LG+TEP+
Sbjct: 611 GAGLPVIETLQNLFKSGDNLICFKGILSGSLSFIFGRLEEGILLSQATREAKELGFTEPN 670
Query: 764 PRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLDQ 943
P DDLSG+DVARK LILAR G I + IKIE L P + T D FL + +LD
Sbjct: 671 PCDDLSGIDVARKLLILARESGYNIELKDIKIEPLLPNNFKIYEDT-DKFLLK-LKELDV 728
Query: 944 SIEERVKRASSNGCVLRYVCVIEGS-SVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYKE 1120
++K+A + G VLR+V IE + + EV ++PL +++ +N + + Y+
Sbjct: 729 YFSNKIKQALNVGNVLRFVATIEQKRQFFIKLEEVNINNPLYKVKNGENALAFYTNYYQP 788
Query: 1121 QPLVIQGAGAGNDTTAAGVFADII 1192
PLV++G GAGN+ TA+GVF+D++
Sbjct: 789 IPLVLRGYGAGNNVTASGVFSDLL 812
>sp|P00562|AK2H_ECOLI Bifunctional aspartokinase/homoserine dehydrogenase 2
OS=Escherichia coli (strain K12) GN=metL PE=1 SV=3
Length = 810
Score = 166 bits (420), Expect = 3e-040
Identities = 103/264 (39%), Positives = 147/264 (55%), Gaps = 8/264 (3%)
Frame = +2
Query: 413 LVVVDCSASSETVEILMKAVDFGCCVVLANKKPLTSTLEHY----DKLVLDPRRIRHEST 580
LVV+D +AS + + + G V+ ANK S Y D R + +T
Sbjct: 543 LVVLDVTASQQLADQYLDFASHGFHVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNAT 602
Query: 581 VGAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDGRPLSLVVRAAKTLGYTEP 760
VGAGLP+ ++ +I SGD + SI G SGTL ++ + + P + +V A G TEP
Sbjct: 603 VGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEP 662
Query: 761 DPRDDLSGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMRPGVMTVDDFLQNGIAKLD 940
DPRDDLSG DV RK +ILAR G I D +++ESL P G ++D F +NG +L+
Sbjct: 663 DPRDDLSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEGG--SIDHFFENG-DELN 719
Query: 941 QSIEERVKRASSNGCVLRYVCVIEGS-SVQVGIREVPKDSPLGRLRGSDNIVEIRSRCYK 1117
+ + +R++ A G VLRYV + + +VG+ V +D PL L DN+ I SR Y+
Sbjct: 720 EQMVQRLEAAREMGLVLRYVARFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYR 779
Query: 1118 EQPLVIQGAGAGNDTTAAGVFADI 1189
+ PLVI+G GAG D TA + +DI
Sbjct: 780 DNPLVIRGPGAGRDVTAGAIQSDI 803
>sp|Q5B998|DHOM_EMENI Homoserine dehydrogenase OS=Emericella nidulans GN=AN2882
PE=1 SV=1
Length = 368
Score = 160 bits (404), Expect = 2e-038
Identities = 96/220 (43%), Positives = 131/220 (59%), Gaps = 10/220 (4%)
Frame = +2
Query: 563 IRHESTVGAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSEL-----EDGRPLSLVV 727
+ HESTVGAGLPVI+++ ++++GD V I G SGTL ++ + S VV
Sbjct: 143 VYHESTVGAGLPVISTLKDLVNTGDEVTRIEGVFSGTLSFLFNTFAPASGSSSAKWSEVV 202
Query: 728 RAAKTLGYTEPDPRDDLSGMDVARKGLILARLLGKRI-IMDSIKIESLYPEEMRPGVMTV 904
AK LGYTEPDPRDDL+GMDVARK ILAR+ G + DS IESL P E+ +
Sbjct: 203 SQAKELGYTEPDPRDDLNGMDVARKLTILARIAGLDVQSPDSFPIESLIPAELTSLPSSA 262
Query: 905 DDFLQ--NGIAKLDQSIEERVKRASSNGCVLRYVCVIE--GSSVQVGIREVPKDSPLGRL 1072
D Q + + D + + A G V+RYV ++ V+VG+++ KDS + L
Sbjct: 263 DGIAQFMARLPEFDSQMAAIKEGAEKAGKVVRYVGSVDVAKKEVRVGLQQFDKDSAIAGL 322
Query: 1073 RGSDNIVEIRSRCYKEQPLVIQGAGAGNDTTAAGVFADII 1192
+GSDNI+ +R Y PL++QGAGAG D TA GV AD++
Sbjct: 323 KGSDNIISFYTRRYGSNPLIVQGAGAGGDVTAMGVTADLL 362
>sp|O94671|DHOM_SCHPO Probable homoserine dehydrogenase OS=Schizosaccharomyces
pombe GN=SPBC776.03 PE=1 SV=1
Length = 376
Score = 142 bits (357), Expect = 7e-033
Identities = 83/218 (38%), Positives = 123/218 (56%), Gaps = 10/218 (4%)
Frame = +2
Query: 563 IRHESTVGAGLPVIASMNRIISSGDPVHSIVGSLSGTLGYVMSELEDG-----RPLSLVV 727
+ HE++VGAGLP+I+++ +I++GD + I G SGTL Y+ + S +V
Sbjct: 147 LMHEASVGAGLPIISTLKELIATGDEIIKIEGIFSGTLSYIFNVWSPNGKKGTASFSDIV 206
Query: 728 RAAKTLGYTEPDPRDDLSGMDVARKGLILARLLGKRI-IMDSIKIESLYPEEMRPGVMTV 904
+ AK GYTEPDPRDDL+GMDVARK IL+R+ G + S ++SL PE ++ V
Sbjct: 207 KIAKQNGYTEPDPRDDLNGMDVARKVTILSRIAGVHVESASSFPVKSLIPEPLKSAV-NA 265
Query: 905 DDFLQNGIAKLDQSIEERVKRASSNGCVLRYV--CVIEGSSVQVGIREVPKDSPLGRLRG 1078
++FL G+ D + A G V+R+V + + V + + P L+
Sbjct: 266 EEFLA-GLPNFDSEFASMREEAEKEGKVVRFVGEADVANKTTLVKLEKYDASHPFANLQS 324
Query: 1079 SDNIVEIRSRCYKEQPLVIQGAGAGNDTTAAGVFADII 1192
SDNI+ ++ Y +PLV+ GAGAG TAAGV D+I
Sbjct: 325 SDNIISFTTKRYHTRPLVVIGAGAGAAVTAAGVLGDMI 362
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,892,683,958
Number of Sequences: 518415
Number of Extensions: 92892683958
Number of Successful Extensions: 611291351
Number of sequences better than 0.0: 0
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