BLASTX 7.6.2
Query= UN22602 /QuerySize=1877
(1876 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O04294|IMA2_ARATH Importin subunit alpha-2 OS=Arabidopsis tha... 854 4e-247
sp|Q96321|IMA1_ARATH Importin subunit alpha-1 OS=Arabidopsis tha... 748 5e-215
sp|O22478|IMA_SOLLC Importin subunit alpha OS=Solanum lycopersic... 735 4e-211
sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryza sativa ... 730 1e-209
sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryza sativa ... 722 2e-207
sp|Q76P29|IMAB_DICDI Importin subunit alpha-B OS=Dictyostelium d... 547 1e-154
sp|O35345|IMA7_MOUSE Importin subunit alpha-7 OS=Mus musculus GN... 496 4e-139
sp|O60684|IMA7_HUMAN Importin subunit alpha-7 OS=Homo sapiens GN... 495 6e-139
sp|Q5RBV0|IMA7_PONAB Importin subunit alpha-7 OS=Pongo abelii GN... 495 6e-139
sp|Q0V7M0|IMA7_BOVIN Importin subunit alpha-7 OS=Bos taurus GN=K... 495 8e-139
sp|Q5R909|IMA1_PONAB Importin subunit alpha-1 OS=Pongo abelii GN... 485 5e-136
sp|P52294|IMA1_HUMAN Importin subunit alpha-1 OS=Homo sapiens GN... 485 6e-136
sp|A2VE08|IMA1_BOVIN Importin subunit alpha-1 OS=Bos taurus GN=K... 484 1e-135
sp|Q56R16|IMA5_RAT Importin subunit alpha-6 OS=Rattus norvegicus... 481 7e-135
sp|O35343|IMA4_MOUSE Importin subunit alpha-4 OS=Mus musculus GN... 427 2e-118
sp|P52293|IMA2_MOUSE Importin subunit alpha-2 OS=Mus musculus GN... 424 1e-117
sp|O00629|IMA4_HUMAN Importin subunit alpha-4 OS=Homo sapiens GN... 424 1e-117
sp|P52292|IMA2_HUMAN Importin subunit alpha-2 OS=Homo sapiens GN... 421 8e-117
sp|P52170|IMA1_XENLA Importin subunit alpha-1 OS=Xenopus laevis ... 410 2e-113
sp|P52171|IMA2_XENLA Importin subunit alpha-2 OS=Xenopus laevis ... 406 5e-112
>sp|O04294|IMA2_ARATH Importin subunit alpha-2 OS=Arabidopsis thaliana GN=KAP2
PE=1 SV=2
Length = 531
Score = 854 bits (2206), Expect = 4e-247
Identities = 429/531 (80%), Positives = 480/531 (90%), Gaps = 5/531 (0%)
Frame = +1
Query: 70 MSLRPSAKTEVRRNRYKVAVDAEEGRRRLEDHMVEIRKNKREENLQKKR-REAISSSSSS 246
MSLRPSAKTEVRRNRYKVAVDAEEGRRR ED++VEIRKNKREENLQKKR +++ S++
Sbjct: 1 MSLRPSAKTEVRRNRYKVAVDAEEGRRRREDNLVEIRKNKREENLQKKRFTSSMAFGSAT 60
Query: 247 SAPQEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVV 426
++ LSSA +L DNLP MV GIWSED+NSQLE T LLRKLLS+EQNPPIN+V+ SGVV
Sbjct: 61 GQTEQDLSSANQLKDNLPAMVAGIWSEDSNSQLEATNLLRKLLSIEQNPPINEVVQSGVV 120
Query: 427 PRLVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQ 606
PR+V FLSRDDFPKLQFEAAWALTNIASGTSENTNVI++SGA+P FI LL+S +E+VREQ
Sbjct: 121 PRVVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQ 180
Query: 607 AVWALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGKPQPSF 786
AVWALGNVAGDSPKCRDLVLS GAM PLLSQF+++TKLSMLRNATWTLSNFCRGKP P+F
Sbjct: 181 AVWALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGKPPPAF 240
Query: 787 EQTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSA 966
EQT PALPVL+RLV+S DEEVLTDACWALSYLSD+SN+KIQ VI+AGV+PRLI LL HS+
Sbjct: 241 EQTQPALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSS 300
Query: 967 PAVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAG 1146
P+VLIPALRTIGNIVTGDDLQTQ VLD Q LP LL+LL N YKKSIKKEACWTISNITAG
Sbjct: 301 PSVLIPALRTIGNIVTGDDLQTQMVLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAG 360
Query: 1147 SSKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPL 1326
++ QIQ VI+AGIIQSL+ VL +AEFEVKKEAAWGISNATSGGTHDQIKF+VSQGCIKPL
Sbjct: 361 NADQIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNATSGGTHDQIKFMVSQGCIKPL 420
Query: 1327 CDLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSH 1506
CDLLTCPD +++TVCLEALENILVVGEA K+LGHTG+DN +A MIDEAEGLEKIENLQSH
Sbjct: 421 CDLLTCPDLKVVTVCLEALENILVVGEAEKNLGHTGEDNLYAQMIDEAEGLEKIENLQSH 480
Query: 1507 DNNDIYQKAVKILETFWTEDDDDDEGANDENHAPQAGFQFGSANVAAPPSQ 1659
DNNDIY KAVKILETFWTED++++ NDENHAPQ+GFQFGS NV PP Q
Sbjct: 481 DNNDIYDKAVKILETFWTEDNEEE--GNDENHAPQSGFQFGSTNV--PPGQ 527
>sp|Q96321|IMA1_ARATH Importin subunit alpha-1 OS=Arabidopsis thaliana GN=KAP1
PE=2 SV=2
Length = 532
Score = 748 bits (1929), Expect = 5e-215
Identities = 362/531 (68%), Positives = 436/531 (82%), Gaps = 2/531 (0%)
Frame = +1
Query: 76 LRPSAKTEVRRNRYKVAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAP 255
LRP+AKTEVRRNRYKVAVDAEEGRRR ED+MVEIRK+KREE+L KKRRE + + P
Sbjct: 3 LRPNAKTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLMKKRREGM--QALQGFP 60
Query: 256 QEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRL 435
+S K +D+L +MV G+WS+D QLE+TT RKLLS+E++PPI +VI++GVVPR
Sbjct: 61 SASAASVDKKLDSLKDMVAGVWSDDPALQLESTTQFRKLLSIERSPPIEEVISAGVVPRF 120
Query: 436 VTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVW 615
V FL ++D+P +QFEAAWALTNIASGTS++T V++ A+P F+ LL SP+++VREQAVW
Sbjct: 121 VEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVW 180
Query: 616 ALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGKPQPSFEQT 795
ALGNVAGDSP+CRDLVL GA+LPLL+Q ++H KLSMLRNATWTLSNFCRGKPQP F+Q
Sbjct: 181 ALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFCRGKPQPHFDQV 240
Query: 796 SPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAV 975
PALP L+RL+ S DEEVLTDACWALSYLSD +N+KIQTVI AGV+P+L++LL H +P+V
Sbjct: 241 KPALPALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSV 300
Query: 976 LIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSK 1155
LIPALRT+GNIVTGDD+QTQ V++ LP L +LLT +KKSIKKEACWTISNITAG+
Sbjct: 301 LIPALRTVGNIVTGDDIQTQCVINSGALPCLANLLTQNHKKSIKKEACWTISNITAGNKD 360
Query: 1156 QIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDL 1335
QIQ V+EA +I L+ +L NAEF++KKEAAW ISNATSGG+HDQIK+LV QGCIKPLCDL
Sbjct: 361 QIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATSGGSHDQIKYLVEQGCIKPLCDL 420
Query: 1336 LTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNN 1515
L CPDPRI+TVCLE LENIL VGEA K+LGHTGD N +A +ID+AEGLEKIENLQSHDNN
Sbjct: 421 LVCPDPRIITVCLEGLENILKVGEAEKNLGHTGDMNYYAQLIDDAEGLEKIENLQSHDNN 480
Query: 1516 DIYQKAVKILETFWTEDDDDDEGANDENHAPQAGFQFGSANVAAPPSQFNF 1668
+IY+KAVKILET+W E++DD+ QAGFQFG P FNF
Sbjct: 481 EIYEKAVKILETYWLEEEDDETQQPPGVDGSQAGFQFGGNQAPVPSGGFNF 531
>sp|O22478|IMA_SOLLC Importin subunit alpha OS=Solanum lycopersicum PE=2 SV=2
Length = 527
Score = 735 bits (1895), Expect = 4e-211
Identities = 363/526 (69%), Positives = 434/526 (82%), Gaps = 7/526 (1%)
Frame = +1
Query: 73 SLRPSAKTEVRRNRYKVAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSA 252
SLRP+++TE RR+RYKVAVDAEEGRRR ED+MVEIRKNKREENL KKRRE + + +
Sbjct: 2 SLRPNSRTEARRSRYKVAVDAEEGRRRREDNMVEIRKNKREENLLKKRREGLLQAQQFPS 61
Query: 253 PQEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPR 432
+S K ++ LPE++ G+WS+D++ QLE TT RKLLS+E+NPPI +VI SGVVPR
Sbjct: 62 -TAAVSHLDKKLETLPELIAGVWSDDSSLQLECTTQFRKLLSIERNPPIEEVIQSGVVPR 120
Query: 433 LVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAV 612
V FL+RDD+P+LQFEAAWALTNIASGTSENT V++ G++P FI LL+SP+++VREQAV
Sbjct: 121 FVEFLARDDYPQLQFEAAWALTNIASGTSENTKVVIDYGSVPIFIRLLSSPSDDVREQAV 180
Query: 613 WALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGKPQPSFEQ 792
WALGN+AGDSPK RDLVL GA++ LL+QF++ KLSMLRNATWTLSNFCRGKPQP FEQ
Sbjct: 181 WALGNIAGDSPKYRDLVLGHGALVALLAQFNEQAKLSMLRNATWTLSNFCRGKPQPLFEQ 240
Query: 793 TSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPA 972
T ALP L RL+ S DEEVLTDACWALSYLSD +N+KIQ VI+AGV RL++LL HS+P+
Sbjct: 241 TKAALPTLGRLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCSRLVELLLHSSPS 300
Query: 973 VLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSS 1152
VLIPALRT+GNIVTGDD+QTQ ++DH LP L++LLT YKKSIKKEACWTISNITAG+
Sbjct: 301 VLIPALRTVGNIVTGDDIQTQVMIDHHALPCLVNLLTQNYKKSIKKEACWTISNITAGNR 360
Query: 1153 KQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCD 1332
QIQ VIEAGII L+ +L NAEFE+KKEAAW ISNATSGG HDQIKFLVSQGCIKPLCD
Sbjct: 361 NQIQIVIEAGIIAPLVYLLQNAEFEIKKEAAWAISNATSGGNHDQIKFLVSQGCIKPLCD 420
Query: 1333 LLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDN 1512
LL CPDPRI+TVCLE LENIL +GEA K LG+T N +A +IDEAEGLEKIENLQSHDN
Sbjct: 421 LLVCPDPRIVTVCLEGLENILKIGEADKDLGNTEGVNVYAQLIDEAEGLEKIENLQSHDN 480
Query: 1513 NDIYQKAVKILETFWTEDDDDDEGANDENHAPQAGFQFGSANVAAP 1650
+IY+KAVKILET+W E++D N++ F+FG A+++ P
Sbjct: 481 TEIYEKAVKILETYWLEEEDVPVSLNEDQ------FEFGGADISLP 520
>sp|Q71VM4|IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryza sativa subsp. japonica
GN=Os01g0253300 PE=1 SV=2
Length = 526
Score = 730 bits (1883), Expect = 1e-209
Identities = 364/524 (69%), Positives = 427/524 (81%), Gaps = 3/524 (0%)
Frame = +1
Query: 76 LRPSAKTEVRRNRYKVAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAP 255
LRPS + EVRRNRYKVAVDAEEGRRR ED+MVEIRK++REE+L KKRRE + + + P
Sbjct: 3 LRPSERVEVRRNRYKVAVDAEEGRRRREDNMVEIRKSRREESLLKKRREGL--QAQAPVP 60
Query: 256 QEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRL 435
+ K +++LP M+ G++S+D N QLE TT RKLLS+E++PPI +VI SGVVPR
Sbjct: 61 ASAATGVDKKLESLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRF 120
Query: 436 VTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVW 615
V FL+R+DFP+LQFEAAWALTNIASGTSENT V++ GA+P F+ LL S +++VREQAVW
Sbjct: 121 VQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVW 180
Query: 616 ALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGKPQPSFEQT 795
ALGNVAGDSPKCRDLVL+ GA+LPLL+Q ++HTKLSMLRNATWTLSNFCRGKPQPSFEQT
Sbjct: 181 ALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQT 240
Query: 796 SPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAV 975
PALP L RL+ S DEEVLTDACWALSYLSD +N+KIQ VI+AGV PRL++LL H +P+V
Sbjct: 241 RPALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSV 300
Query: 976 LIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSK 1155
LIPALRT+GNIVTGDD QTQ ++DHQ LP LL LLT KKSIKKEACWTISNITAG+
Sbjct: 301 LIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKD 360
Query: 1156 QIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDL 1335
QIQ VI AGII L+ +L AEF++KKEAAW ISNATSGG+HDQIK+LVS+GCIKPLCDL
Sbjct: 361 QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDL 420
Query: 1336 LTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNN 1515
L CPD RI+TVCLE LENIL VGE K+L GD N F+ MIDEAEGLEKIENLQSHDNN
Sbjct: 421 LICPDIRIVTVCLEGLENILKVGETDKTLA-AGDVNVFSQMIDEAEGLEKIENLQSHDNN 479
Query: 1516 DIYQKAVKILETFWTEDDDDDEGANDENHAPQAGFQFGSANVAA 1647
+IY+KAVKILE +W +++DD GA A F FG AA
Sbjct: 480 EIYEKAVKILEAYWMDEEDDTMGATTVAAPQGATFDFGQGGGAA 523
>sp|Q9SLX0|IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryza sativa subsp. japonica
GN=Os05g0155500 PE=1 SV=2
Length = 534
Score = 722 bits (1863), Expect = 2e-207
Identities = 357/531 (67%), Positives = 438/531 (82%), Gaps = 8/531 (1%)
Frame = +1
Query: 70 MSLRPSAKTEVRRNRYKVAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSS 249
MSLRPS + EVRR+RYKVAVDA+EGRRR ED+MVEIRK++REE+L KKRR+ + ++++++
Sbjct: 1 MSLRPSERAEVRRSRYKVAVDADEGRRRREDNMVEIRKSRREESLLKKRRDGLPAAAAAA 60
Query: 250 APQEGL----SSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIAS 417
A L S+ ++ ++ LP MV + S+D+ QLE TT RKLLS+E++PPI +VI +
Sbjct: 61 AAASPLLAHSSALQQKLEGLPAMVQAVQSDDSAVQLEATTQFRKLLSIERSPPIEEVINT 120
Query: 418 GVVPRLVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEV 597
GVVPR + FL R+D+P+LQFEAAWALTNIASGTS+NT V+V+SGA+P F+ LL+SP+E+V
Sbjct: 121 GVVPRFIAFLQREDYPQLQFEAAWALTNIASGTSDNTKVVVESGAVPIFVKLLSSPSEDV 180
Query: 598 REQAVWALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGKPQ 777
REQAVWALGNVAGDSPKCRDLVL+ G + PLL Q ++H KLSMLRNATWTLSNFCRGKPQ
Sbjct: 181 REQAVWALGNVAGDSPKCRDLVLASGGLYPLLQQLNEHAKLSMLRNATWTLSNFCRGKPQ 240
Query: 778 PSFEQTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLA 957
P+FEQ PAL L+RL+ S DEEVLTDACWALSYLSD +N+KIQ VI++GV PRL++LL
Sbjct: 241 PNFEQVKPALSALQRLIHSQDEEVLTDACWALSYLSDGTNDKIQAVIESGVFPRLVELLM 300
Query: 958 HSAPAVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNI 1137
H + +VLIPALRT+GNIVTGDD+QTQ V+DHQ LP LL+LLTN +KKSIKKEACWTISNI
Sbjct: 301 HPSASVLIPALRTVGNIVTGDDMQTQCVIDHQALPCLLNLLTNNHKKSIKKEACWTISNI 360
Query: 1138 TAGSSKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCI 1317
TAG+ +QIQ VI A II L+ +L AEF++KKEAAW ISNATSGGTHDQIK+LV+QGCI
Sbjct: 361 TAGNREQIQAVINANIIAPLVHLLQTAEFDIKKEAAWAISNATSGGTHDQIKYLVAQGCI 420
Query: 1318 KPLCDLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENL 1497
KPLCDLL CPDPRI+TVCLE LENIL VGEA K+LG GD N +A MID+AEGLEKIENL
Sbjct: 421 KPLCDLLVCPDPRIVTVCLEGLENILKVGEAEKNLG-AGDVNSYAQMIDDAEGLEKIENL 479
Query: 1498 QSHDNNDIYQKAVKILETFWTEDDDDDEGANDENHAPQAGFQFGSANVAAP 1650
QSHDN +IY+KAVK+LE++W E++DD + D Q GF FG+ P
Sbjct: 480 QSHDNTEIYEKAVKMLESYWLEEEDDAMPSGDN---AQNGFNFGNQQPNVP 527
>sp|Q76P29|IMAB_DICDI Importin subunit alpha-B OS=Dictyostelium discoideum
GN=DDB_G0272318 PE=3 SV=1
Length = 516
Score = 547 bits (1409), Expect = 1e-154
Identities = 292/501 (58%), Positives = 372/501 (74%), Gaps = 11/501 (2%)
Frame = +1
Query: 88 AKTEVRRNRYKVAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGL 267
+K E R+++YK ++D++E RR+ E+ + IRKNKREE+L KKR +A+ S+ P +
Sbjct: 4 SKQETRKSQYKKSIDSDESRRKREEASLSIRKNKREESLLKKRTQAVPGST----PVKVD 59
Query: 268 SSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRLVTFL 447
S + ++ LP +V I SE+ + L++TT RKLLS+E++PPI +VI +G+VPRLV FL
Sbjct: 60 SLINQRLEQLPSLVAEINSENPDLILKSTTAFRKLLSIEKSPPIEEVIKTGIVPRLVKFL 119
Query: 448 SRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVWALGN 627
DFP+LQFEAAWALTNIASGT E T V++++GAI F+ LL+SP+++VREQAVWALGN
Sbjct: 120 YMQDFPQLQFEAAWALTNIASGTPEQTRVVIENGAIQVFVLLLSSPHDDVREQAVWALGN 179
Query: 628 VAGDSPKCRDLVLSLGAMLPLLSQFHDHT--KLSMLRNATWTLSNFCRGKPQPSFEQTSP 801
+AGDS CRDLVLS A+ PLLS + K+SM+RNATWTLSNFCRGKPQP FE
Sbjct: 180 IAGDSHYCRDLVLSHNALPPLLSLLQNPAAIKVSMVRNATWTLSNFCRGKPQPPFEIVRA 239
Query: 802 ALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAVLI 981
+LPVL +L+ DEEVL DACWALSYLSD SNE+IQ VIDA V ++++LL H AV
Sbjct: 240 SLPVLAKLIYYQDEEVLIDACWALSYLSDGSNERIQEVIDAKVCRKMVELLGHPTIAVQT 299
Query: 982 PALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSKQI 1161
PALRTIGNIVTGDD QTQ VL Q L LL+LL +P K++I+KEACWTISNITAG QI
Sbjct: 300 PALRTIGNIVTGDDNQTQIVLSVQALSHLLNLLQSP-KRAIRKEACWTISNITAGDKNQI 358
Query: 1162 QGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDLLT 1341
Q VI+A II SL+ +L NAEFE++KEAAW ISNATS GT QI FLVSQGC+KPLCDLL
Sbjct: 359 QQVIDANIIPSLVYLLANAEFEIQKEAAWAISNATSCGTPQQIHFLVSQGCVKPLCDLLK 418
Query: 1342 CPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNNDI 1521
DPRI+ V LE +ENILV G+ K TG NP+ +I++A+GL KI +LQ H N D
Sbjct: 419 VSDPRIINVALEGIENILVAGK--KEAQVTG-VNPYKKIIEDADGLGKIYDLQHHMNKDT 475
Query: 1522 YQKAVKILETFWTEDDDDDEG 1584
++K +I+ T+ ED+ +DEG
Sbjct: 476 FEKVSRIISTY-LEDEQEDEG 495
>sp|O35345|IMA7_MOUSE Importin subunit alpha-7 OS=Mus musculus GN=Kpna6 PE=1
SV=2
Length = 536
Score = 496 bits (1275), Expect = 4e-139
Identities = 275/514 (53%), Positives = 353/514 (68%), Gaps = 9/514 (1%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRR-EAISSSSS---SSAP 255
K R YK A++ EE RRR E+ +++RK KRE+ L K+R E I+ ++ S
Sbjct: 9 KDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLM 68
Query: 256 QEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVI-ASGVVPR 432
+SS EMV ++S+D++ QL TT RKLLS E +PPI++VI GVV R
Sbjct: 69 DSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDR 128
Query: 433 LVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAV 612
V FL R++ LQFEAAWALTNIASGTS+ T +++++GA+P FI LL S E+V+EQAV
Sbjct: 129 FVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAV 188
Query: 613 WALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFE 789
WALGN+AGDS CRD VL+ + PLL+ T+L+M RNA W LSN CRGK P P F
Sbjct: 189 WALGNIAGDSSLCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFA 248
Query: 790 QTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAP 969
+ SP LPVL RL+ S+D ++L DACWALSYLSD NEKIQ VID+GV RL++LL H+
Sbjct: 249 KVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDY 308
Query: 970 AVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGS 1149
V PALR +GNIVTGDD+QTQ +L+ LP LLHLL++ K+SI+KEACWTISNITAG+
Sbjct: 309 KVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSS-KESIRKEACWTISNITAGN 367
Query: 1150 SKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLC 1329
QIQ VI+A I LI +L AEF +KEAAW I+NATSGGT +QI++LVS GCIKPLC
Sbjct: 368 RAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLC 427
Query: 1330 DLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHD 1509
DLLT D +I+ V L LENIL +GE +G NP+ +I+EA GL+KIE LQSH+
Sbjct: 428 DLLTVMDSKIVQVALNGLENILRLGEQESKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHE 486
Query: 1510 NNDIYQKAVKILETFWTEDDDDDEGANDENHAPQ 1611
N +IYQKA ++E ++ +DDD A + Q
Sbjct: 487 NQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQ 520
>sp|O60684|IMA7_HUMAN Importin subunit alpha-7 OS=Homo sapiens GN=KPNA6 PE=1
SV=1
Length = 536
Score = 495 bits (1273), Expect = 6e-139
Identities = 275/514 (53%), Positives = 353/514 (68%), Gaps = 9/514 (1%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRR-EAISSSSS---SSAP 255
K R YK A++ EE RRR E+ +++RK KRE+ L K+R E I+ ++ S
Sbjct: 9 KDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLM 68
Query: 256 QEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVI-ASGVVPR 432
+SS EMV ++S+D++ QL TT RKLLS E +PPI++VI VV R
Sbjct: 69 DSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDR 128
Query: 433 LVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAV 612
V FL R++ LQFEAAWALTNIASGTS+ T +++++GA+P FI LL S E+V+EQAV
Sbjct: 129 FVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAV 188
Query: 613 WALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFE 789
WALGN+AGDS CRD VL+ + PLL+ T+L+M RNA W LSN CRGK P P F
Sbjct: 189 WALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFA 248
Query: 790 QTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAP 969
+ SP LPVL RL+ S+D ++L DACWALSYLSD NEKIQ VID+GV RL++LL H+
Sbjct: 249 KVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDY 308
Query: 970 AVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGS 1149
V PALR +GNIVTGDD+QTQ +L+ LP LLHLL++P K+SI+KEACWTISNITAG+
Sbjct: 309 KVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSP-KESIRKEACWTISNITAGN 367
Query: 1150 SKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLC 1329
QIQ VI+A I LI +L AEF +KEAAW I+NATSGGT +QI++LVS GCIKPLC
Sbjct: 368 RAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLC 427
Query: 1330 DLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHD 1509
DLLT D +I+ V L LENIL +GE +G NP+ +I+EA GL+KIE LQSH+
Sbjct: 428 DLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHE 486
Query: 1510 NNDIYQKAVKILETFWTEDDDDDEGANDENHAPQ 1611
N +IYQKA ++E ++ +DDD A + Q
Sbjct: 487 NQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQ 520
>sp|Q5RBV0|IMA7_PONAB Importin subunit alpha-7 OS=Pongo abelii GN=KPNA6 PE=2
SV=1
Length = 536
Score = 495 bits (1273), Expect = 6e-139
Identities = 275/514 (53%), Positives = 353/514 (68%), Gaps = 9/514 (1%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRR-EAISSSSS---SSAP 255
K R YK A++ EE RRR E+ +++RK KRE+ L K+R E I+ ++ S
Sbjct: 9 KDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLM 68
Query: 256 QEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVI-ASGVVPR 432
+SS EMV ++S+D++ QL TT RKLLS E +PPI++VI VV R
Sbjct: 69 DSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDR 128
Query: 433 LVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAV 612
V FL R++ LQFEAAWALTNIASGTS+ T +++++GA+P FI LL S E+V+EQAV
Sbjct: 129 FVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAV 188
Query: 613 WALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFE 789
WALGN+AGDS CRD VL+ + PLL+ T+L+M RNA W LSN CRGK P P F
Sbjct: 189 WALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFA 248
Query: 790 QTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAP 969
+ SP LPVL RL+ S+D ++L DACWALSYLSD NEKIQ VID+GV RL++LL H+
Sbjct: 249 KVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDY 308
Query: 970 AVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGS 1149
V PALR +GNIVTGDD+QTQ +L+ LP LLHLL++P K+SI+KEACWTISNITAG+
Sbjct: 309 KVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSP-KESIRKEACWTISNITAGN 367
Query: 1150 SKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLC 1329
QIQ VI+A I LI +L AEF +KEAAW I+NATSGGT +QI++LVS GCIKPLC
Sbjct: 368 RAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLC 427
Query: 1330 DLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHD 1509
DLLT D +I+ V L LENIL +GE +G NP+ +I+EA GL+KIE LQSH+
Sbjct: 428 DLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHE 486
Query: 1510 NNDIYQKAVKILETFWTEDDDDDEGANDENHAPQ 1611
N +IYQKA ++E ++ +DDD A + Q
Sbjct: 487 NQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQ 520
>sp|Q0V7M0|IMA7_BOVIN Importin subunit alpha-7 OS=Bos taurus GN=KPNA6 PE=2 SV=1
Length = 536
Score = 495 bits (1272), Expect = 8e-139
Identities = 275/514 (53%), Positives = 352/514 (68%), Gaps = 9/514 (1%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRR-EAISSSSS---SSAP 255
K R YK A++ EE RRR E+ +++RK KRE+ L K+R E I+ ++ S
Sbjct: 9 KDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLM 68
Query: 256 QEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVI-ASGVVPR 432
+SS EMV ++S+D + QL TT RKLLS E +PPI++VI GVV R
Sbjct: 69 DSYVSSTTGESVITREMVEMLFSDDPDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDR 128
Query: 433 LVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAV 612
V FL R++ LQFEAAWALTNIASGTS+ T +++++GA+P FI LL S E+V+EQAV
Sbjct: 129 FVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAV 188
Query: 613 WALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFE 789
WALGN+AGDS CRD VL+ + PLL+ T+L+M RNA W LSN CRGK P P F
Sbjct: 189 WALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFA 248
Query: 790 QTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAP 969
+ SP LPVL RL+ S+D ++L DACWALSYLSD NEKIQ VID+GV RL++LL H+
Sbjct: 249 KVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDN 308
Query: 970 AVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGS 1149
V PALR +GNIVTGDD+QTQ +L+ LP LLHLL++ K+SI+KEACWTISNITAG+
Sbjct: 309 KVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSS-KESIRKEACWTISNITAGN 367
Query: 1150 SKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLC 1329
QIQ VI+A I LI +L AEF +KEAAW I+NATSGGT +QI++LVS GCIKPLC
Sbjct: 368 RAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLC 427
Query: 1330 DLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHD 1509
DLLT D +I+ V L LENIL +GE +G NP+ +I+EA GL+KIE LQSH+
Sbjct: 428 DLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSG-VNPYCGLIEEAYGLDKIEFLQSHE 486
Query: 1510 NNDIYQKAVKILETFWTEDDDDDEGANDENHAPQ 1611
N +IYQKA ++E ++ +DDD A + Q
Sbjct: 487 NQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQ 520
>sp|Q5R909|IMA1_PONAB Importin subunit alpha-1 OS=Pongo abelii GN=KPNA1 PE=2
SV=1
Length = 538
Score = 485 bits (1248), Expect = 5e-136
Identities = 271/534 (50%), Positives = 349/534 (65%), Gaps = 25/534 (4%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGL 267
K R YK +++ +E RRR E+ +++RK KREE L K+R A + +
Sbjct: 6 KENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDG 65
Query: 268 SSAKKLIDNL---------PEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIAS- 417
+ I+N+ +M+ I+S+ QL T RKLLS E NPPI++VI++
Sbjct: 66 GFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTP 125
Query: 418 GVVPRLVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEV 597
GVV R V FL R + LQFE+AW LTNIASG S T +++Q+GA+P FI LL+S E+V
Sbjct: 126 GVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDV 185
Query: 598 REQAVWALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-P 774
+EQAVWALGN+AGDS CRD VL + PLL F +L+M RNA W LSN CRGK P
Sbjct: 186 QEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
Query: 775 QPSFEQTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLL 954
P F + SP L VL L+ +D +VL DACWALSYLSD N+KIQ VIDAGV RL++LL
Sbjct: 246 PPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELL 305
Query: 955 AHSAPAVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISN 1134
H+ V+ PALR +GNIVTGDD+QTQ +L+ L LLHLL++P K+SIKKEACWTISN
Sbjct: 306 MHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACWTISN 364
Query: 1135 ITAGSSKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGC 1314
ITAG+ QIQ VI+A I +LI +L AEF +KEAAW I+NATSGG+ +QIK+LV GC
Sbjct: 365 ITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGC 424
Query: 1315 IKPLCDLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIEN 1494
IKPLCDLLT D +I+ V L LENIL +GE TG NP+ +I+EA GL+KIE
Sbjct: 425 IKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTG-INPYCALIEEAYGLDKIEF 483
Query: 1495 LQSHDNNDIYQKAVKILETFWTEDDDDDEGA-----NDENH------APQAGFQ 1623
LQSH+N +IYQKA ++E ++ +D+D A N + + AP GFQ
Sbjct: 484 LQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQ 537
>sp|P52294|IMA1_HUMAN Importin subunit alpha-1 OS=Homo sapiens GN=KPNA1 PE=1
SV=3
Length = 538
Score = 485 bits (1247), Expect = 6e-136
Identities = 271/534 (50%), Positives = 348/534 (65%), Gaps = 25/534 (4%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGL 267
K R YK +++ +E RRR E+ +++RK KREE L K+R A + +
Sbjct: 6 KENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDG 65
Query: 268 SSAKKLIDNL---------PEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIAS- 417
+ I N+ +M+ I+S+ QL T RKLLS E NPPI++VI++
Sbjct: 66 GFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTP 125
Query: 418 GVVPRLVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEV 597
GVV R V FL R + LQFE+AW LTNIASG S T +++Q+GA+P FI LL+S E+V
Sbjct: 126 GVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDV 185
Query: 598 REQAVWALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-P 774
+EQAVWALGN+AGDS CRD VL + PLL F +L+M RNA W LSN CRGK P
Sbjct: 186 QEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
Query: 775 QPSFEQTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLL 954
P F + SP L VL L+ +D +VL DACWALSYLSD N+KIQ VIDAGV RL++LL
Sbjct: 246 PPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELL 305
Query: 955 AHSAPAVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISN 1134
H+ V+ PALR +GNIVTGDD+QTQ +L+ L LLHLL++P K+SIKKEACWTISN
Sbjct: 306 MHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACWTISN 364
Query: 1135 ITAGSSKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGC 1314
ITAG+ QIQ VI+A I +LI +L AEF +KEAAW I+NATSGG+ +QIK+LV GC
Sbjct: 365 ITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGC 424
Query: 1315 IKPLCDLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIEN 1494
IKPLCDLLT D +I+ V L LENIL +GE TG NP+ +I+EA GL+KIE
Sbjct: 425 IKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTG-INPYCALIEEAYGLDKIEF 483
Query: 1495 LQSHDNNDIYQKAVKILETFWTEDDDDDEGA-----NDENH------APQAGFQ 1623
LQSH+N +IYQKA ++E ++ +D+D A N + + AP GFQ
Sbjct: 484 LQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQ 537
>sp|A2VE08|IMA1_BOVIN Importin subunit alpha-1 OS=Bos taurus GN=KPNA1 PE=2 SV=1
Length = 538
Score = 484 bits (1244), Expect = 1e-135
Identities = 270/534 (50%), Positives = 346/534 (64%), Gaps = 25/534 (4%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGL 267
K R YK +++ +E RRR E+ +++RK KREE L K+R A + +
Sbjct: 6 KENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDG 65
Query: 268 SSAKKLIDNL---------PEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIAS- 417
+ I+N+ +M+ I+S QL T RKLLS E NPPI++VI++
Sbjct: 66 GFHEAQINNMEMAPGGVITSDMIEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVISTP 125
Query: 418 GVVPRLVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEV 597
GVV R V FL R + LQFE+AW LTNIASG S T +++Q+GA+P FI LL+S E+V
Sbjct: 126 GVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDV 185
Query: 598 REQAVWALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-P 774
+EQAVWALGN+AGDS CRD VL + PLL F +L+M RNA W LSN CRGK P
Sbjct: 186 QEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
Query: 775 QPSFEQTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLL 954
P F + SP L VL L+ +D +VL DACWALSYLSD N+KIQ VIDAGV RL++LL
Sbjct: 246 PPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELL 305
Query: 955 AHSAPAVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISN 1134
H+ V+ PALR +GNIVTGDD+QTQ +L+ L LLHLL++P K+SIKKEACWTISN
Sbjct: 306 MHNDYKVVSPALRAVGNIVTGDDVQTQVILNCSALQSLLHLLSSP-KESIKKEACWTISN 364
Query: 1135 ITAGSSKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGC 1314
ITAG+ QIQ VI+A I +LI +L AEF +KEAAW I+NATSGG+ +QIK+LV GC
Sbjct: 365 ITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGC 424
Query: 1315 IKPLCDLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIEN 1494
IKPLCDLLT D +I+ V L LENIL +GE TG NP+ +I+EA GL+KIE
Sbjct: 425 IKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTG-INPYCALIEEAYGLDKIEF 483
Query: 1495 LQSHDNNDIYQKAVKILETFWTEDDDDDEGAN-----------DENHAPQAGFQ 1623
LQSH+N +IYQKA ++E ++ +D+D A + AP GFQ
Sbjct: 484 LQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQ 537
>sp|Q56R16|IMA5_RAT Importin subunit alpha-6 OS=Rattus norvegicus GN=Kpna5 PE=2
SV=1
Length = 536
Score = 481 bits (1238), Expect = 7e-135
Identities = 264/513 (51%), Positives = 344/513 (67%), Gaps = 28/513 (5%)
Frame = +1
Query: 91 KTEVRRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAI------------- 228
K R YK A++ +E RRR E+ +++RK KREE L K+R ++
Sbjct: 6 KDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPRNDDCMLESPIQ 65
Query: 229 --SSSSSSSAPQEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPIN 402
SS+ P+E + +A +M+ I+S + QL T RKLLS E NPPI+
Sbjct: 66 DPDVSSTVPIPEEDMITA--------DMIQMIFSNNAEQQLTATQKFRKLLSKEPNPPID 117
Query: 403 DVIAS-GVVPRLVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLT 579
VI GVV R V FL R++ LQFEAAWALTNIASGT +T V++++GA+P FI LLT
Sbjct: 118 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIRLLT 177
Query: 580 SPNEEVREQAVWALGNVAGDSPKCRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNF 759
S +E+V+EQAVWALGN+AGD+ +CRD VL+ + PLL + +L+ RNA W LSN
Sbjct: 178 SEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL 237
Query: 760 CRGK-PQPSFEQTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIP 936
CRGK P P+F + SP L VL RL+ S+D +VL D CWALSYLSD N+KIQ VID+GV
Sbjct: 238 CRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQVVIDSGVCR 297
Query: 937 RLIDLLAHSAPAVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEA 1116
RL++LL H+ V+ PALR +GNIVTGDD+QTQ +L+ LP LLHLL +P K+S++KEA
Sbjct: 298 RLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLGSP-KESVRKEA 356
Query: 1117 CWTISNITAGSSKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKF 1296
CWTISNITAG+ QIQ VI+ I LI VL AEF +KEAAW I+NATSGG +QI++
Sbjct: 357 CWTISNITAGNRMQIQAVIDGSIFPVLIEVLQKAEFRTRKEAAWAITNATSGGAPEQIRY 416
Query: 1297 LVSQGCIKPLCDLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEG 1476
LV+ GCIKPLCDLLT D +I+ V L LENIL +GE G NP+ +I+EA G
Sbjct: 417 LVTLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGERESKQNGVG-INPYCALIEEAYG 475
Query: 1477 LEKIENLQSHDNNDIYQKAVKILETFWTEDDDD 1575
L+KIE LQSH+N +IYQKA ++E ++ ++DD
Sbjct: 476 LDKIEFLQSHENQEIYQKAFDLIERYFGVEEDD 508
>sp|O35343|IMA4_MOUSE Importin subunit alpha-4 OS=Mus musculus GN=Kpna4 PE=2
SV=1
Length = 521
Score = 427 bits (1096), Expect = 2e-118
Identities = 236/520 (45%), Positives = 315/520 (60%), Gaps = 40/520 (7%)
Frame = +1
Query: 130 DAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGLSSAKKL-----IDN 294
D E RR+ + +VE+RKNKR+E+L K+R + PQE + + + N
Sbjct: 21 DLETMRRQRNEVVVELRKNKRDEHLLKRR----------NVPQEDICEDSDIDGDYRVQN 70
Query: 295 --LPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRLVTFLSRDDFPK 468
L +V S++ QL RKLLS ++NPPI+D+I SG++P LV L RDD P
Sbjct: 71 TSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPS 130
Query: 469 LQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVWALGNVAGDSPK 648
LQFEAAWALTNIASGTSE T +VQS A+P F+ LL SP++ V EQAVWALGN+ GD P+
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 649 CRDLVLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFEQTSPALPVLKRL 825
CRD V+SLG + PLLS ++ LRN TW + N CR K P P E LP L L
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVL 250
Query: 826 VESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAVLIPALRTIGN 1005
+ TD +L D WALSYL+D+ NE+IQ VID+G++P L+ LL+H V ALR +GN
Sbjct: 251 IHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGN 310
Query: 1006 IVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSKQIQGVIEAGI 1185
IVTG D QTQ VL+ L LLT+P K+ I KEA W +SNITAG+ +Q+Q VI+A +
Sbjct: 311 IVTGTDEQTQVVLNCDALSHFPALLTHP-KEKINKEAVWFLSNITAGNQQQVQAVIDANL 369
Query: 1186 IQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDLLTCPDPRILT 1365
+ +I +L +F +KEAAW ISN T G DQ+ +L+ Q I P C+LLT D +++
Sbjct: 370 VPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQ 429
Query: 1366 VCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNNDIYQKAVKIL 1545
V L+ L NIL + E A +I+E GLEKIE LQ+H+N DIY+ A +I+
Sbjct: 430 VVLDGLSNILKMAE--------DQAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEII 481
Query: 1546 ETFWTEDDDDDE-------------GANDENHAPQAGFQF 1626
+ F++ DD D++ G N + P GFQF
Sbjct: 482 DQFFSSDDIDEDPSLVPESVQGGTFGFNSSTNVPTEGFQF 521
>sp|P52293|IMA2_MOUSE Importin subunit alpha-2 OS=Mus musculus GN=Kpna2 PE=1
SV=2
Length = 529
Score = 424 bits (1089), Expect = 1e-117
Identities = 234/513 (45%), Positives = 332/513 (64%), Gaps = 13/513 (2%)
Frame = +1
Query: 103 RRNRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGLSSAK 279
R NR+K D+ E RRR + VE+RK K++E + K+R + ++S QE ++
Sbjct: 13 RLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 280 KLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRLVTFLSRDD 459
+ ++ ++V GI S + SQL+ T RKLLS E+ PPI+++I +G++P+ V+FL + D
Sbjct: 73 TVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTD 132
Query: 460 FPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVWALGNVAGD 639
+QFE+AWALTNIASGTSE T +V GAIP+FI LL SP+ + EQAVWALGN+AGD
Sbjct: 133 CSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGD 192
Query: 640 SPKCRDLVLSLGAMLPLLS--QFHDHTKLS--MLRNATWTLSNFCRGK-PQPSFEQTSPA 804
RDLV+ GA+ PLL+ D + L+ LRN TWTLSN CR K P P +
Sbjct: 193 GSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQI 252
Query: 805 LPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAVLIP 984
LP L RL+ D EVL D+CWA+SYL+D NE+I+ V+ GV+P+L+ LL + ++ P
Sbjct: 253 LPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTP 312
Query: 985 ALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSKQIQ 1164
ALR IGNIVTG D QTQ V+D L LLTNP K +I+KEA WT+SNITAG QIQ
Sbjct: 313 ALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNP-KTNIQKEATWTMSNITAGRQDQIQ 371
Query: 1165 GVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDLLTC 1344
V+ G++ L+GVL A+F+ +KEAAW I+N TSGGT +QI +LV G I+PL +LL+
Sbjct: 372 QVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSA 431
Query: 1345 PDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNNDIY 1524
D +I+ V L+A+ NI +A + LG T + MI+E GL+KIE LQ H+N +Y
Sbjct: 432 KDTKIIQVILDAISNIF---QAAEKLGET---EKLSIMIEECGGLDKIEALQRHENESVY 485
Query: 1525 QKAVKILETFWTEDDDDDEGANDENHAPQAGFQ 1623
+ ++ ++E +++ ++++D+ E + FQ
Sbjct: 486 KASLNLIEKYFSVEEEEDQNVVPETTSEGFAFQ 518
>sp|O00629|IMA4_HUMAN Importin subunit alpha-4 OS=Homo sapiens GN=KPNA4 PE=1
SV=1
Length = 521
Score = 424 bits (1089), Expect = 1e-117
Identities = 234/516 (45%), Positives = 313/516 (60%), Gaps = 32/516 (6%)
Frame = +1
Query: 130 DAEEGRRRLEDHMVEIRKNKREENLQKKR---REAISSSSSSSAPQEGLSSAKKLIDNLP 300
D E RR+ + +VE+RKNKR+E+L K+R E I S ++ +L
Sbjct: 21 DLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNT------SLE 74
Query: 301 EMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRLVTFLSRDDFPKLQFE 480
+V S++ QL RKLLS ++NPPI+D+I SG++P LV L RDD P LQFE
Sbjct: 75 AIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFE 134
Query: 481 AAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVWALGNVAGDSPKCRDL 660
AAWALTNIASGTSE T +VQS A+P F+ LL SP++ V EQAVWALGN+ GD P+CRD
Sbjct: 135 AAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY 194
Query: 661 VLSLGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFEQTSPALPVLKRLVEST 837
V+SLG + PLLS ++ LRN TW + N CR K P P E LP L L+ T
Sbjct: 195 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHT 254
Query: 838 DEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAVLIPALRTIGNIVTG 1017
D +L D WALSYL+D+ NE+IQ VID+G++P L+ LL+H V ALR +GNIVTG
Sbjct: 255 DVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTG 314
Query: 1018 DDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSKQIQGVIEAGIIQSL 1197
D QTQ VL+ L LLT+P K+ I KEA W +SNITAG+ +Q+Q VI+A ++ +
Sbjct: 315 TDEQTQVVLNCDALSHFPALLTHP-KEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMI 373
Query: 1198 IGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDLLTCPDPRILTVCLE 1377
I +L +F +KEAAW ISN T G DQ+ +L+ Q I P C+LLT D +++ V L+
Sbjct: 374 IHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLD 433
Query: 1378 ALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNNDIYQKAVKILETFW 1557
L NIL + E + +I+E GLEKIE LQ+H+N DIY+ A +I++ F+
Sbjct: 434 GLSNILKMAE--------DEAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFF 485
Query: 1558 TEDDDDDE-------------GANDENHAPQAGFQF 1626
+ DD D++ G N + P GFQF
Sbjct: 486 SSDDIDEDPSLVPEAIQGGTFGFNSSANVPTEGFQF 521
>sp|P52292|IMA2_HUMAN Importin subunit alpha-2 OS=Homo sapiens GN=KPNA2 PE=1
SV=1
Length = 529
Score = 421 bits (1082), Expect = 8e-117
Identities = 235/525 (44%), Positives = 334/525 (63%), Gaps = 14/525 (2%)
Frame = +1
Query: 70 MSLRPSAKTEVRR-NRYK-VAVDAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSS 243
MS +A T R +R+K D+ E RRR + VE+RK K+++ + K+R + +
Sbjct: 1 MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 244 SSAPQEGLSSAKKLIDNLPEMVIGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGV 423
+S QE ++ + ++ ++V GI S + +QL+ T RKLLS E+ PPI+++I +G+
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGL 120
Query: 424 VPRLVTFLSRDDFPKLQFEAAWALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVRE 603
+P+ V+FL R D +QFE+AWALTNIASGTSE T +V GAIP+FI LL SP+ + E
Sbjct: 121 IPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISE 180
Query: 604 QAVWALGNVAGDSPKCRDLVLSLGAMLPLLS--QFHDHTKLS--MLRNATWTLSNFCRGK 771
QAVWALGN+AGD RDLV+ GA+ PLL+ D + L+ LRN TWTLSN CR K
Sbjct: 181 QAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNK 240
Query: 772 -PQPSFEQTSPALPVLKRLVESTDEEVLTDACWALSYLSDSSNEKIQTVIDAGVIPRLID 948
P P + LP L RL+ D EVL D CWA+SYL+D NE+I V+ GV+P+L+
Sbjct: 241 NPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 949 LLAHSAPAVLIPALRTIGNIVTGDDLQTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTI 1128
LL S ++ PALR IGNIVTG D QTQ V+D L LLTNP K +I+KEA WT+
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 1129 SNITAGSSKQIQGVIEAGIIQSLIGVLHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQ 1308
SNITAG QIQ V+ G++ L+ VL A+F+ +KEA W ++N TSGGT +QI +LV
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 1309 GCIKPLCDLLTCPDPRILTVCLEALENILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKI 1488
G I+PL +LLT D +I+ V L+A+ NI +A + LG T + MI+E GL+KI
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIF---QAAEKLGET---EKLSIMIEECGGLDKI 473
Query: 1489 ENLQSHDNNDIYQKAVKILETFWTEDDDDDEGANDENHAPQAGFQ 1623
E LQ+H+N +Y+ ++ ++E +++ ++++D+ E + FQ
Sbjct: 474 EALQNHENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQ 518
>sp|P52170|IMA1_XENLA Importin subunit alpha-1 OS=Xenopus laevis GN=kpna1 PE=1
SV=2
Length = 522
Score = 410 bits (1053), Expect = 2e-113
Identities = 213/484 (44%), Positives = 310/484 (64%), Gaps = 8/484 (1%)
Frame = +1
Query: 130 DAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGLSSAKKLIDNLPEMV 309
D E RRR + VE+RK K++E + K+R + S + + S + +L E+V
Sbjct: 20 DTAELRRRRVEVSVELRKAKKDEQILKRRNVCLPEELILSPEKNAMQSVQVPPLSLEEIV 79
Query: 310 IGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRLVTFLSRDDFPKLQFEAAW 489
G+ S D ++L T RK+LS E+NPP+ND+I +G++P+LV FLSR D LQFEAAW
Sbjct: 80 QGMNSGDPENELRCTQAARKMLSRERNPPLNDIIEAGLIPKLVEFLSRHDNSTLQFEAAW 139
Query: 490 ALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVWALGNVAGDSPKCRDLVLS 669
ALTNIASGTS+ T +V GAIP+FI L++SP+ + EQAVWALGN+AGD P RD +++
Sbjct: 140 ALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRDALIN 199
Query: 670 LGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFEQTSPALPVLKRLVESTDEE 846
+ PLL+ + T L LRN TW LSN CR K P P LPVL +L+ D++
Sbjct: 200 CNVIPPLLALVNPQTPLGYLRNITWMLSNLCRNKNPYPPMSAVLQILPVLTQLMHHDDKD 259
Query: 847 VLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAVLIPALRTIGNIVTGDDL 1026
+L+D CWA+SYL+D SN++I V+ G++ RLI L+ +++ P+LRT+GNIVTG D
Sbjct: 260 ILSDTCWAMSYLTDGSNDRIDVVVKTGIVDRLIQLMYSPELSIVTPSLRTVGNIVTGTDK 319
Query: 1027 QTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSKQIQGVIEAGIIQSLIGV 1206
QTQ +D VL L LL + K SI+KEA W ISNI AG + QIQ +I G++ L+ +
Sbjct: 320 QTQAAIDAGVLSVLPQLLRH-QKPSIQKEAAWAISNIAAGPAPQIQQMITCGLLSPLVDL 378
Query: 1207 LHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDLLTCPDPRILTVCLEALE 1386
L+ +F+ +KEA W ++N TSGGT +Q+ LV G ++PL +LLT D + + V L+A+
Sbjct: 379 LNKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAIS 438
Query: 1387 NILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNNDIYQKAVKILETFWTED 1566
NI + E + G+ +++E GLEKIE LQ+HDN+ +Y A+ ++E +++ +
Sbjct: 439 NIFLAAEKL------GEQEKLCLLVEELGGLEKIEALQTHDNHMVYHAALALIEKYFSGE 492
Query: 1567 DDDD 1578
+ DD
Sbjct: 493 EADD 496
>sp|P52171|IMA2_XENLA Importin subunit alpha-2 OS=Xenopus laevis GN=kpna2 PE=1
SV=2
Length = 523
Score = 406 bits (1041), Expect = 5e-112
Identities = 213/487 (43%), Positives = 309/487 (63%), Gaps = 8/487 (1%)
Frame = +1
Query: 130 DAEEGRRRLEDHMVEIRKNKREENLQKKRREAISSSSSSSAPQEGLSSAKKLIDNLPEMV 309
D E RRR + VE+RK K++E + K+R S + + S + +L E+V
Sbjct: 20 DTAELRRRRVEVSVELRKAKKDEQILKRRNVCFPEELILSPEKNAMQSIQVPQLSLEEIV 79
Query: 310 IGIWSEDTNSQLETTTLLRKLLSLEQNPPINDVIASGVVPRLVTFLSRDDFPKLQFEAAW 489
G+ S D ++L +T RK+LS E+NPP+ND+I +G++P+LV FLS + LQFEAAW
Sbjct: 80 QGMNSGDNENELRSTQAARKMLSKERNPPLNDIIEAGLIPKLVEFLSYHNNSTLQFEAAW 139
Query: 490 ALTNIASGTSENTNVIVQSGAIPSFIHLLTSPNEEVREQAVWALGNVAGDSPKCRDLVLS 669
ALTNIASGTS+ T +V GAIP+FI L++SP+ + EQAVWALGN+AGD P RD ++S
Sbjct: 140 ALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRDALIS 199
Query: 670 LGAMLPLLSQFHDHTKLSMLRNATWTLSNFCRGK-PQPSFEQTSPALPVLKRLVESTDEE 846
+ PLL+ + T L LRN TWTLSN CR K P P LPVL +L+ D++
Sbjct: 200 CNVIPPLLTLVNPQTPLGYLRNITWTLSNLCRNKNPYPPMSAVLQILPVLTQLMLHEDKD 259
Query: 847 VLTDACWALSYLSDSSNEKIQTVIDAGVIPRLIDLLAHSAPAVLIPALRTIGNIVTGDDL 1026
+L+D CWA+SYL+D SN++I V+ G++ RLI L+ ++L P+LRT+GNIVTG D
Sbjct: 260 ILSDTCWAMSYLTDGSNDRIDVVVKTGLVERLIQLMYSPELSILTPSLRTVGNIVTGTDK 319
Query: 1027 QTQTVLDHQVLPRLLHLLTNPYKKSIKKEACWTISNITAGSSKQIQGVIEAGIIQSLIGV 1206
QTQ +D VL L LL + K SI+KEA W +SNI AG + QIQ +I G++ L+ +
Sbjct: 320 QTQAAIDAGVLSVLPQLLRH-QKPSIQKEAAWALSNIAAGPAPQIQQMITCGLLSPLVDL 378
Query: 1207 LHNAEFEVKKEAAWGISNATSGGTHDQIKFLVSQGCIKPLCDLLTCPDPRILTVCLEALE 1386
L +F+ +KEA W ++N TSGGT +Q+ LV G ++PL +LLT D + + V L+A+
Sbjct: 379 LKKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAIS 438
Query: 1387 NILVVGEAVKSLGHTGDDNPFATMIDEAEGLEKIENLQSHDNNDIYQKAVKILETFWTED 1566
NI + E + G+ +++E GLEKIE LQ+HDN +Y A+ ++E +++ +
Sbjct: 439 NIFLAAEKL------GEQEKLCLLVEELGGLEKIEALQTHDNRMVYHAALALIEKYFSGE 492
Query: 1567 DDDDEGA 1587
+ D+ A
Sbjct: 493 EADEMNA 499
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,892,683,958
Number of Sequences: 518415
Number of Extensions: 92892683958
Number of Successful Extensions: 611291351
Number of sequences better than 0.0: 0
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