BLASTX 7.6.2
Query= UN22659 /QuerySize=956
(955 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q2TBG8|UCHL3_BOVIN Ubiquitin carboxyl-terminal hydrolase isoz... 221 7e-057
sp|P15374|UCHL3_HUMAN Ubiquitin carboxyl-terminal hydrolase isoz... 220 2e-056
sp|Q06AB3|UCHL3_PIG Ubiquitin carboxyl-terminal hydrolase isozym... 218 4e-056
sp|Q9JKB1|UCHL3_MOUSE Ubiquitin carboxyl-terminal hydrolase isoz... 218 6e-056
sp|Q91Y78|UCHL3_RAT Ubiquitin carboxyl-terminal hydrolase isozym... 216 2e-055
sp|P58321|UCHL4_MOUSE Ubiquitin carboxyl-terminal hydrolase isoz... 208 8e-053
sp|Q54T48|UCHL_DICDI Probable ubiquitin carboxyl-terminal hydrol... 204 9e-052
sp|P09936|UCHL1_HUMAN Ubiquitin carboxyl-terminal hydrolase isoz... 188 5e-047
sp|Q60HC8|UCHL1_MACFA Ubiquitin carboxyl-terminal hydrolase isoz... 186 2e-046
sp|Q9R0P9|UCHL1_MOUSE Ubiquitin carboxyl-terminal hydrolase isoz... 185 4e-046
sp|Q6SEG5|UCHL1_PIG Ubiquitin carboxyl-terminal hydrolase isozym... 185 4e-046
sp|Q00981|UCHL1_RAT Ubiquitin carboxyl-terminal hydrolase isozym... 185 4e-046
sp|Q9GM50|UCHL1_HORSE Ubiquitin carboxyl-terminal hydrolase isoz... 185 5e-046
sp|P35122|UCHL_DROME Ubiquitin carboxyl-terminal hydrolase OS=Dr... 175 4e-043
sp|O01391|UCHL_APLCA Ubiquitin carboxyl-terminal hydrolase OS=Ap... 169 4e-041
sp|P23356|UCHL1_BOVIN Ubiquitin carboxyl-terminal hydrolase isoz... 145 6e-034
sp|Q10171|UBLH1_SCHPO Probable ubiquitin carboxyl-terminal hydro... 108 6e-023
>sp|Q2TBG8|UCHL3_BOVIN Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Bos
taurus GN=UCHL3 PE=2 SV=1
Length = 230
Score = 221 bits (562), Expect = 7e-057
Identities = 116/226 (51%), Positives = 154/226 (68%), Gaps = 6/226 (2%)
Frame = -2
Query: 852 KRWLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKS 673
+RWLPLEANP+V NQF+ LGL P+ + DV+G+D ELL MVP+PV AVL L+P+T+K
Sbjct: 4 QRWLPLEANPEVTNQFLKQLGLHPN-WQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKY 62
Query: 672 EEERIEQDKEIKEKVH--SDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKF 499
E R E++++IK + + VYFMKQT+ NACGTIGL+HAI N ++ GS L KF
Sbjct: 63 EVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKF 122
Query: 498 FKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPA---SEDVNTHFICLACVNGELYE 328
+ +A MSP ER R+LEN I H + G+T A E V+ HFI L V+G LYE
Sbjct: 123 LEESASMSPEERARYLENYDAIRVTHETSAHEGQTEAPNIDEKVDLHFIALVHVDGHLYE 182
Query: 327 LDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
LDGRK P++HG +S TLL+DA +V KK +E++PD L FN +A+S
Sbjct: 183 LDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALS 228
>sp|P15374|UCHL3_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Homo
sapiens GN=UCHL3 PE=1 SV=1
Length = 230
Score = 220 bits (558), Expect = 2e-056
Identities = 115/226 (50%), Positives = 153/226 (67%), Gaps = 6/226 (2%)
Frame = -2
Query: 852 KRWLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKS 673
+RWLPLEANP+V NQF+ LGL P+ + DV+G+D ELL MVP+PV AVL L+P+T+K
Sbjct: 4 QRWLPLEANPEVTNQFLKQLGLHPN-WQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKY 62
Query: 672 EEERIEQDKEIKEKVH--SDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKF 499
E R E++++IK + + VYFMKQT+ NACGTIGL+HAI N ++ GS L KF
Sbjct: 63 EVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKF 122
Query: 498 FKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPA---SEDVNTHFICLACVNGELYE 328
+ + MSP ER R+LEN I H + G+T A E V+ HFI L V+G LYE
Sbjct: 123 LEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYE 182
Query: 327 LDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
LDGRK P++HG +S TLL+DA +V KK +E++PD L FN +A+S
Sbjct: 183 LDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALS 228
>sp|Q06AB3|UCHL3_PIG Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Sus
scrofa GN=UCHL3 PE=2 SV=1
Length = 230
Score = 218 bits (555), Expect = 4e-056
Identities = 115/226 (50%), Positives = 155/226 (68%), Gaps = 6/226 (2%)
Frame = -2
Query: 852 KRWLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKS 673
+RWLPLEANP+V NQF+ LGL P+ + DV+G+D ELL MVP+PV AVL L+P+T+K
Sbjct: 4 QRWLPLEANPEVTNQFLKQLGLHPN-WQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKY 62
Query: 672 EEERIEQDKEIKEKVH--SDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKF 499
E R E++++IK + + VYFMKQT+ NACGTIGL+HAI N +++ GS L KF
Sbjct: 63 EVFRTEEEEKIKSQGQDVTPSVYFMKQTISNACGTIGLIHAIANNKNKMHFESGSTLKKF 122
Query: 498 FKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPA---SEDVNTHFICLACVNGELYE 328
+ +A MSP ER R+LE+ I H + G+T A E V+ HFI L V+G LYE
Sbjct: 123 LEESASMSPDERARYLESYDAIPVTHETSAHEGQTEAPNIDEKVDLHFIALVHVDGHLYE 182
Query: 327 LDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
LDGRK P++HG +S TLL+DA +V KK +E++PD L FN +A+S
Sbjct: 183 LDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALS 228
>sp|Q9JKB1|UCHL3_MOUSE Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Mus
musculus GN=Uchl3 PE=1 SV=2
Length = 230
Score = 218 bits (554), Expect = 6e-056
Identities = 114/226 (50%), Positives = 153/226 (67%), Gaps = 6/226 (2%)
Frame = -2
Query: 852 KRWLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKS 673
+RWLPLEANP+V NQF+ LGL P+ + DV+G++ ELL MVP+PV AVL L+P+T+K
Sbjct: 4 QRWLPLEANPEVTNQFLKQLGLHPN-WQFVDVYGMEPELLSMVPRPVCAVLLLFPITEKY 62
Query: 672 EEERIEQDKEIKEKVH--SDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKF 499
E R E++++IK + + VYFMKQT+ NACGTIGL+HAI N ++ GS L KF
Sbjct: 63 EVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKF 122
Query: 498 FKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPA---SEDVNTHFICLACVNGELYE 328
+ + MSP ER +FLEN I H + G+T A E V+ HFI L V+G LYE
Sbjct: 123 LEESVSMSPEERAKFLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYE 182
Query: 327 LDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
LDGRK P++HG +S TLL+DA +V KK +E++PD L FN +A+S
Sbjct: 183 LDGRKPFPINHGKTSDETLLEDAIEVCKKFMERDPDELRFNAIALS 228
>sp|Q91Y78|UCHL3_RAT Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Rattus
norvegicus GN=Uchl3 PE=1 SV=1
Length = 230
Score = 216 bits (549), Expect = 2e-055
Identities = 114/226 (50%), Positives = 152/226 (67%), Gaps = 6/226 (2%)
Frame = -2
Query: 852 KRWLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKS 673
+RWLPLEANP+V NQF+ LGL P+ + DV+G++ ELL MVP+PV AVL L+P+T+K
Sbjct: 4 QRWLPLEANPEVTNQFLKQLGLHPN-WQFVDVYGMEPELLSMVPRPVCAVLLLFPITEKY 62
Query: 672 EEERIEQDKEIKEKVH--SDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKF 499
E R E++++IK + + VYFMKQT+ NACGTIGL+HAI N ++ GS L KF
Sbjct: 63 EVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSALKKF 122
Query: 498 FKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPA---SEDVNTHFICLACVNGELYE 328
+ + MSP ER R LEN I H + G+T A E V+ HFI L V+G LYE
Sbjct: 123 LEESVAMSPEERARHLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYE 182
Query: 327 LDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
LDGRK P++HG +S TLL+DA +V KK +E++PD L FN +A+S
Sbjct: 183 LDGRKPFPINHGKTSDETLLEDAIEVCKKFMERDPDELRFNAIALS 228
>sp|P58321|UCHL4_MOUSE Ubiquitin carboxyl-terminal hydrolase isozyme L4 OS=Mus
musculus GN=Uchl4 PE=1 SV=1
Length = 233
Score = 208 bits (527), Expect = 8e-053
Identities = 110/229 (48%), Positives = 151/229 (65%), Gaps = 9/229 (3%)
Frame = -2
Query: 852 KRWLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKS 673
+RWLPLEANP+V NQF+ LGL P+ + DV+G++ ELL ++P+PV AVL L+P+T+K
Sbjct: 4 QRWLPLEANPEVTNQFLKQLGLHPN-WQFVDVYGMESELLSIIPRPVCAVLLLFPITEKY 62
Query: 672 EEERIEQDKEIKEKVH--SDKVYFMKQTVGNAC---GTIGLLHAIGNISSEIKLSEGSFL 508
E R E++++IK + + VYFMKQT+ NAC GTIGL+HAI N ++ GS L
Sbjct: 63 EVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGTIGLIHAIANNKDKVHFESGSTL 122
Query: 507 DKFFKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPA---SEDVNTHFICLACVNGE 337
KF + + MSP ER ++LEN I H + G+T A E V+ HFI L V+G
Sbjct: 123 KKFLEESVSMSPEERAKYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGH 182
Query: 336 LYELDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
LYELDG K P++HG +S TLL+D KV KK +E++PD L FN +A+S
Sbjct: 183 LYELDGWKPFPINHGKTSDETLLEDVIKVCKKFMERDPDELRFNAIALS 231
>sp|Q54T48|UCHL_DICDI Probable ubiquitin carboxyl-terminal hydrolase
OS=Dictyostelium discoideum GN=uch1 PE=3 SV=1
Length = 255
Score = 204 bits (518), Expect = 9e-052
Identities = 103/228 (45%), Positives = 153/228 (67%), Gaps = 6/228 (2%)
Frame = -2
Query: 852 KRWLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKS 673
K W+PLEANP+V+ FM LG++ D C D++G+D+ LLEMVP P +AV+ L+P+T +
Sbjct: 12 KNWIPLEANPEVLTTFMQSLGVSKDWEFC-DIYGIDEGLLEMVPSPCVAVILLFPITNEY 70
Query: 672 EEERIEQDKEIKEK--VHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKF 499
E++R + +KEI+EK V SDKVYFMKQ +GNACGTIG++H++ N ++ I+ +E F +F
Sbjct: 71 EDKRYKLEKEIEEKGQVLSDKVYFMKQYIGNACGTIGVIHSVLNNANVIEFNENGFFKQF 130
Query: 498 FKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGET---PASEDVNTHFICLACVNGELYE 328
T +S ER L +S+IE +H + G++ E V HF+ V+G LYE
Sbjct: 131 LDKTTSLSTEERAISLLKNSEIEKSHEISALQGQSNVPQEDEPVVLHFVSFVHVDGHLYE 190
Query: 327 LDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISKR 184
LDGRK ++HG SS TLLKD A V++K+I+++P + FN+M + K+
Sbjct: 191 LDGRKPFAINHGESSAETLLKDTANVLQKMIDEDPKEIRFNLMGLVKK 238
>sp|P09936|UCHL1_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo
sapiens GN=UCHL1 PE=1 SV=2
Length = 223
Score = 188 bits (477), Expect = 5e-047
Identities = 98/218 (44%), Positives = 138/218 (63%), Gaps = 1/218 (0%)
Frame = -2
Query: 840 PLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEEER 661
P+E NP+++N+ + LG+A + DV GL++E L VP P A+L L+PLT + E R
Sbjct: 5 PMEINPEMLNKVLSRLGVA-GQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFR 63
Query: 660 IEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFKTTAK 481
+Q +E+K + S KVYFMKQT+GN+CGTIGL+HA+ N ++ +GS L +F T K
Sbjct: 64 KKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEK 123
Query: 480 MSPMERGRFLENDSQIEDAHSAAVTAGETPASEDVNTHFICLACVNGELYELDGRKAGPV 301
MSP +R + E + I+ AH A G+ + VN HFI V+G LYELDGR PV
Sbjct: 124 MSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPV 183
Query: 300 SHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISK 187
+HGASS TLLKDAAKV ++ E+ + F+ +A+ K
Sbjct: 184 NHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCK 221
>sp|Q60HC8|UCHL1_MACFA Ubiquitin carboxyl-terminal hydrolase isozyme L1
OS=Macaca fascicularis GN=UCHL1 PE=2 SV=1
Length = 223
Score = 186 bits (472), Expect = 2e-046
Identities = 96/218 (44%), Positives = 138/218 (63%), Gaps = 1/218 (0%)
Frame = -2
Query: 840 PLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEEER 661
P+E NP+++N+ + LG+A + DV GL+++ L VP P A+L L+PLT + E R
Sbjct: 5 PMEINPEMLNKVLSRLGVA-GQWRFVDVLGLEEDSLGSVPAPACALLLLFPLTAQHENFR 63
Query: 660 IEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFKTTAK 481
+Q +E+K + S KVYFMKQT+GN+CGTIGL+HA+ N ++ +GS L +F T K
Sbjct: 64 KKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEK 123
Query: 480 MSPMERGRFLENDSQIEDAHSAAVTAGETPASEDVNTHFICLACVNGELYELDGRKAGPV 301
MSP +R + E + I+ AH A G+ + VN HFI V+G LYELDGR PV
Sbjct: 124 MSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPV 183
Query: 300 SHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISK 187
+HGASS TLL+DAAKV ++ E+ + F+ +A+ K
Sbjct: 184 NHGASSEGTLLQDAAKVCREFTEREQGEVRFSAVALCK 221
>sp|Q9R0P9|UCHL1_MOUSE Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Mus
musculus GN=Uchl1 PE=1 SV=1
Length = 223
Score = 185 bits (469), Expect = 4e-046
Identities = 94/218 (43%), Positives = 139/218 (63%), Gaps = 1/218 (0%)
Frame = -2
Query: 840 PLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEEER 661
P+E NP+++N+ + LG+A + DV GL++E L VP P A+L L+PLT + E R
Sbjct: 5 PMEINPEMLNKVLAKLGVA-GQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFR 63
Query: 660 IEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFKTTAK 481
+Q +E+K + S KVYFMKQT+GN+CGTIGL+HA+ N +++ +GS L +F T K
Sbjct: 64 KKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEK 123
Query: 480 MSPMERGRFLENDSQIEDAHSAAVTAGETPASEDVNTHFICLACVNGELYELDGRKAGPV 301
+SP +R + E + I+ AH + G+ + VN HFI V+G LYELDGR PV
Sbjct: 124 LSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPV 183
Query: 300 SHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISK 187
+HGASS +LL+DAAKV ++ E+ + F+ +A+ K
Sbjct: 184 NHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCK 221
>sp|Q6SEG5|UCHL1_PIG Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Sus
scrofa GN=UCHL1 PE=2 SV=1
Length = 223
Score = 185 bits (469), Expect = 4e-046
Identities = 95/218 (43%), Positives = 138/218 (63%), Gaps = 1/218 (0%)
Frame = -2
Query: 840 PLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEEER 661
P+E NP+++N+ + LG+A DV GL++E L VP P A+L L+PLT + E R
Sbjct: 5 PMEINPEMLNKVLTRLGVA-GHWRFADVLGLEEESLGSVPAPACALLLLFPLTAQHENFR 63
Query: 660 IEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFKTTAK 481
+Q +E+K + S KVYFMKQT+GN+CGTIGL+HA+ N +++ +GS L +F T K
Sbjct: 64 KKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEK 123
Query: 480 MSPMERGRFLENDSQIEDAHSAAVTAGETPASEDVNTHFICLACVNGELYELDGRKAGPV 301
+SP +R + E + I+ AH A G+ + VN HFI V+G LYELDGR PV
Sbjct: 124 LSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPV 183
Query: 300 SHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISK 187
+HGASS +LL+DAAKV ++ E+ + F+ +A+ K
Sbjct: 184 NHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCK 221
>sp|Q00981|UCHL1_RAT Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Rattus
norvegicus GN=Uchl1 PE=1 SV=2
Length = 223
Score = 185 bits (469), Expect = 4e-046
Identities = 94/218 (43%), Positives = 139/218 (63%), Gaps = 1/218 (0%)
Frame = -2
Query: 840 PLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEEER 661
P+E NP+++N+ + LG+A + DV GL++E L VP P A+L L+PLT + E R
Sbjct: 5 PMEINPEMLNKVLAKLGVA-GQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFR 63
Query: 660 IEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFKTTAK 481
+Q +E+K + S KVYFMKQT+GN+CGTIGL+HA+ N +++ +GS L +F T K
Sbjct: 64 KKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEK 123
Query: 480 MSPMERGRFLENDSQIEDAHSAAVTAGETPASEDVNTHFICLACVNGELYELDGRKAGPV 301
+SP +R + E + I+ AH + G+ + VN HFI V+G LYELDGR PV
Sbjct: 124 LSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPV 183
Query: 300 SHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISK 187
+HGASS +LL+DAAKV ++ E+ + F+ +A+ K
Sbjct: 184 NHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCK 221
>sp|Q9GM50|UCHL1_HORSE Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Equus
caballus GN=UCHL1 PE=2 SV=2
Length = 223
Score = 185 bits (468), Expect = 5e-046
Identities = 95/218 (43%), Positives = 138/218 (63%), Gaps = 1/218 (0%)
Frame = -2
Query: 840 PLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEEER 661
P+E NP+++N+ + LG+A + DV GL++E L VP P A+L L+PLT + E R
Sbjct: 5 PMEINPEMLNKVLARLGVA-GQWRFVDVLGLEEETLGSVPAPACALLLLFPLTAQHENFR 63
Query: 660 IEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFKTTAK 481
+Q +E+K + S KVYFMKQT+GN+CGTIGL+HA+ N +++ +GS L +F T K
Sbjct: 64 KKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEK 123
Query: 480 MSPMERGRFLENDSQIEDAHSAAVTAGETPASEDVNTHFICLACVNGELYELDGRKAGPV 301
+SP +R + E + I+ AH A G+ + VN HFI V+G LYELDGR PV
Sbjct: 124 LSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPV 183
Query: 300 SHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISK 187
+HGASS LL+DAAKV ++ E+ + F+ +A+ K
Sbjct: 184 NHGASSEDLLLQDAAKVCREFTEREQGEVRFSAVALCK 221
>sp|P35122|UCHL_DROME Ubiquitin carboxyl-terminal hydrolase OS=Drosophila
melanogaster GN=Uch PE=2 SV=2
Length = 227
Score = 175 bits (443), Expect = 4e-043
Identities = 91/223 (40%), Positives = 140/223 (62%), Gaps = 7/223 (3%)
Frame = -2
Query: 846 WLPLEANPDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEE 667
W PLE+NP+V+ +++ LG++P DV GL+D+ LE +P+PV A + L+P ++ E+
Sbjct: 4 WTPLESNPEVLTKYIHKLGVSP-AWSVTDVIGLEDDTLEWIPRPVKAFILLFPCSETYEK 62
Query: 666 ERIEQDKEIK--EKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFK 493
R E+ IK E+ H + +++M+Q NACGT+ L+H++ N + E+ + G D F +
Sbjct: 63 HRAEEHDRIKEVEEQHPEDLFYMRQFTHNACGTVALIHSVAN-NKEVDIDRGVLKD-FLE 120
Query: 492 TTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPAS--EDVNTHFICLACVNGELYELDG 319
TA +SP ERGR LE D + H A G+T A+ E V HFI L G LYELDG
Sbjct: 121 KTASLSPEERGRALEKDEKFTADHEALAQEGQTNAANHEKVIHHFIALVNKEGTLYELDG 180
Query: 318 RKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
RK+ P+ HG +S T +KDAAKV K+ + ++P+ + F V+A++
Sbjct: 181 RKSFPIKHGPTSEETFVKDAAKVCKEFMARDPNEVRFTVLALT 223
>sp|O01391|UCHL_APLCA Ubiquitin carboxyl-terminal hydrolase OS=Aplysia
californica GN=UCH PE=2 SV=1
Length = 214
Score = 169 bits (426), Expect = 4e-041
Identities = 88/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = -2
Query: 858 SAKRWLPLEANPDVMNQFMWGLGLAPDEVECN--DVFGLDDELLEMVPKPVLAVLFLYPL 685
S +RW+PLE+NP V+N+++ LG+ + N DVFGLD ELL MVP+P A++ L+P
Sbjct: 3 SEQRWIPLESNPKVLNKYVHNLGM---DAGWNFVDVFGLDPELLAMVPRPAAALVLLFPD 59
Query: 684 TKKSEEERIEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLD 505
K++ + I + + + D +Y+ KQT+GNACGT+ ++HA+ N + I
Sbjct: 60 DKETVNQLIGE----YQSDYPDSLYYTKQTIGNACGTVAIVHALANNENVIPFDAAKHFK 115
Query: 504 KFFKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPA---SEDVNTHFICLACVNGEL 334
F + T ++P ER + LE D+ + AH G+T A E V +HF+ L NG L
Sbjct: 116 TFLEKTKPLNPEERAKHLEQDNLMGAAHGDCAQEGDTQAPSQDEHVKSHFVALVHCNGTL 175
Query: 333 YELDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPD 220
YELDGRK PV HG +S T L+DAA+V+KK + ++P+
Sbjct: 176 YELDGRKEAPVVHGTTSADTFLEDAAEVVKKFMARDPE 213
>sp|P23356|UCHL1_BOVIN Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Bos
taurus GN=UCHL1 PE=1 SV=2
Length = 252
Score = 145 bits (364), Expect = 6e-034
Identities = 72/167 (43%), Positives = 104/167 (62%)
Frame = -2
Query: 687 LTKKSEEERIEQDKEIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFL 508
L + E R +Q +E+K + S KVYFMKQT+GN+CGTIGL+HA+ N +++ +GS L
Sbjct: 84 LVSQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVL 143
Query: 507 DKFFKTTAKMSPMERGRFLENDSQIEDAHSAAVTAGETPASEDVNTHFICLACVNGELYE 328
+F T K+SP +R + E + I+ AH A G+ + VN HFI V+G LYE
Sbjct: 144 KQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYE 203
Query: 327 LDGRKAGPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAISK 187
LDGR PV+HG SS +LL+DAAKV ++ E+ + F+ +A+ K
Sbjct: 204 LDGRMPFPVNHGTSSEDSLLQDAAKVCREFTEREQGEVRFSAVALCK 250
>sp|Q10171|UBLH1_SCHPO Probable ubiquitin carboxyl-terminal hydrolase 1
OS=Schizosaccharomyces pombe GN=uch1 PE=2 SV=1
Length = 222
Score = 108 bits (269), Expect = 6e-023
Identities = 78/220 (35%), Positives = 119/220 (54%), Gaps = 16/220 (7%)
Frame = -2
Query: 825 PDVMNQFMWGLGLAPDEVECNDVFGLDDELLEMVPKPVLAVLFLYPLTKKSEEERIEQDK 646
P+V+ ++ +G+ + D+F L +E+ E +P+PV A+LF++P S + I +
Sbjct: 9 PEVLEPYLQKIGV--QDASVFDLFSL-EEIPEYIPRPVHALLFVFP---SSGTKTIYKGS 62
Query: 645 EIKEKVHSDKVYFMKQTVGNACGTIGLLHAIGNISSEIKLSEGSFLDKFFKTTAKMSPME 466
I K SDKV + QT+ NACGTIGLLHA+ N K++E F+ +T S E
Sbjct: 63 RILPK-DSDKVLWYPQTIPNACGTIGLLHAVSNGELRRKVNENDFIKSLIRTAEGSSIEE 121
Query: 465 RGRFLENDSQIEDAHSA-AVTAGETPAS-EDVNT--HFICL----ACVNGELYELDGRKA 310
R + +E+ ++E H+A A E S EDV T HFIC + + YELDGR+
Sbjct: 122 RAKLIEDSKELEALHAAFAGPPLEVEGSEEDVETDLHFICFVKGKSKDDNHFYELDGRQE 181
Query: 309 GPVSHGASSPATLLKDAAKVIKKIIEKNPDTLNFNVMAIS 190
GPV H L + VIK I+ + D+ F+++AI+
Sbjct: 182 GPVQHSEIESDLLNAEVLSVIKNYIQ-SIDSPFFSLVAIT 220
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,819,846,109
Number of Sequences: 518415
Number of Extensions: 95819846109
Number of Successful Extensions: 619733697
Number of sequences better than 0.0: 0
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