BLASTX 7.6.2
Query= UN22667 /QuerySize=1647
(1646 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53780|METC_ARATH Cystathionine beta-lyase, chloroplastic OS=... 483 2e-135
sp|O94350|CBL_SCHPO Cystathionine beta-lyase OS=Schizosaccharomy... 186 5e-046
sp|O05394|MCCB_BACSU Cystathionine gamma-lyase OS=Bacillus subti... 178 2e-043
sp|O31632|METC_BACSU Cystathionine beta-lyase metC OS=Bacillus s... 175 1e-042
sp|Q83A83|METC_COXBU Cystathionine beta-lyase OS=Coxiella burnet... 168 1e-040
sp|P0C2T9|METC_LACLC Cystathionine beta-lyase OS=Lactococcus lac... 168 1e-040
sp|P0A4K2|METC_LACLA Cystathionine beta-lyase OS=Lactococcus lac... 168 2e-040
sp|A2RM21|METC_LACLM Cystathionine beta-lyase OS=Lactococcus lac... 168 2e-040
sp|Q55DV9|CGL_DICDI Cystathionine gamma-lyase OS=Dictyostelium d... 166 4e-040
sp|O31631|METB_BACSU Cystathionine gamma-synthase OS=Bacillus su... 166 4e-040
sp|P56069|METB_HELPY Cystathionine gamma-synthase OS=Helicobacte... 162 8e-039
sp|P24601|METB_HERAU Probable cystathionine gamma-synthase (Frag... 160 4e-038
sp|P44502|METB_HAEIN Cystathionine gamma-synthase OS=Haemophilus... 158 2e-037
sp|Q9ZMW7|METB_HELPJ Cystathionine gamma-synthase OS=Helicobacte... 158 2e-037
sp|P66876|METB_MYCBO Cystathionine gamma-synthase OS=Mycobacteri... 157 3e-037
sp|P66875|METB_MYCTU Cystathionine gamma-synthase OS=Mycobacteri... 157 3e-037
>sp|P53780|METC_ARATH Cystathionine beta-lyase, chloroplastic OS=Arabidopsis
thaliana GN=At3g57050 PE=1 SV=1
Length = 464
Score = 483 bits (1242), Expect = 2e-135
Identities = 246/303 (81%), Positives = 271/303 (89%), Gaps = 4/303 (1%)
Frame = -2
Query: 1516 SSLSLHSSLVPSFADLHDRGLVSKNSPTTVSVTKFPTWEKKKKKQISNRNLFKLSCVMEK 1337
SSLSLHSS VPSFADL DRGL+SKNSPT+VS++K PTWE KKQISNRN FKL+CVMEK
Sbjct: 3 SSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWE---KKQISNRNSFKLNCVMEK 59
Query: 1336 SIDGNTHSVVDTTQDCLNAVNVREEASVATLLMNLDNKFDPFDAMSTPLYQTATFKQPSA 1157
S+DG THS V+ T D LN +N++EEASV+TLL+NLDNKFDPFDAMSTPLYQTATFKQPSA
Sbjct: 60 SVDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSA 119
Query: 1156 IENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALAAVTHLLKSGDELVAGDD 977
IENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAAL+AVTHL+K+G+E+VAGDD
Sbjct: 120 IENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDD 179
Query: 976 LYGGSDRLLSNVVPRSGVVVNE*H-N*FRGVAAAIGPRTKLVWLESPTNPRQQISDIRKI 800
+YGGSDRLLS VVPRSGVVV + VAAAIGP+TKLVWLESPTNPRQQISDIRKI
Sbjct: 180 VYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKI 239
Query: 799 AEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDLMGGCAFCKRRKIG 620
+EMAHAQGAL+LVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSD+M G K K+
Sbjct: 240 SEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLA 299
Query: 619 KGI 611
K +
Sbjct: 300 KEV 302
Score = 332 bits (850), Expect = 6e-090
Identities = 165/177 (93%), Positives = 172/177 (97%)
Frame = -3
Query: 654 AGVLSVKGEKLAKELYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLF 475
AGVL+VKGEKLAKE+YFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYL
Sbjct: 288 AGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLS 347
Query: 474 THPRVKQVYHAGLPDHPGHHLHFFQAKGAGSVFSFITGSVALFKHLVETTKYFSIAVSFG 295
+HPRVK+VY+AGLPDHPGHHLHF QAKGAGSVFSFITGSVAL KHLVETTKYFSIAVSFG
Sbjct: 348 SHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFG 407
Query: 294 SVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDADDLISDLDIAFRTGPI 124
SVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIED DDLISDLDIAF+T P+
Sbjct: 408 SVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL 464
>sp|O94350|CBL_SCHPO Cystathionine beta-lyase OS=Schizosaccharomyces pombe
GN=str3 PE=2 SV=4
Length = 390
Score = 186 bits (471), Expect = 5e-046
Identities = 107/219 (48%), Positives = 140/219 (63%), Gaps = 3/219 (1%)
Frame = -2
Query: 1258 SVATLLMNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKL 1079
SV T L++++ D + A S P+YQ+ATFKQP G +DYTRSGNPTR L+ LAKL
Sbjct: 8 SVDTELVHVEGNEDQYHASSVPIYQSATFKQPCLEHMGKFDYTRSGNPTRSVLQVHLAKL 67
Query: 1078 DKADRAFCFTSGMAALAAVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVV-NE*HN 902
KA AF ++GM+AL + KS +VAG DLYGGSDRLLS + G V N +
Sbjct: 68 MKAKHAFVTSNGMSALDMILRCCKSNSHVVAGHDLYGGSDRLLSFNQRQYGFKVDNVDTS 127
Query: 901 *FRGVAAAIGPRTKLVWLESPTNPRQQISDIRKIAEM--AHAQGALLLVDNSIMSPVLSR 728
AA+ P T LV +ESPTNPR I DIR I ++ + A+ ALL++DN+++SPVL
Sbjct: 128 DLAAFEAALRPDTNLVLIESPTNPRISICDIRAIVKITRSKAKDALLVMDNTMLSPVLCN 187
Query: 727 PLELGADIVMHSATKFIAGHSDLMGGCAFCKRRKIGKGI 611
PL+ G DIV SATK+++GH DLMGG K +I K +
Sbjct: 188 PLDFGYDIVYESATKYLSGHHDLMGGVIATKSDEIAKSV 226
Score = 164 bits (413), Expect = 3e-039
Identities = 88/171 (51%), Positives = 121/171 (70%), Gaps = 3/171 (1%)
Frame = -3
Query: 651 GVLSVKGEKLAKELYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLFT 472
GV++ K +++AK ++F N+ G+ +APF+C+L LRGIKTM LR+E+ Q+NA +IA +L
Sbjct: 213 GVIATKSDEIAKSVFFNINAMGAAMAPFECFLLLRGIKTMGLRVERAQQNAIEIAKFL-- 270
Query: 471 HPRVKQVYHAGL-PDHPGHHLHFFQAKGAGSVFSFITGSVALFKHLVETTKYFSIAVSFG 295
+ QV GL PD + + A+G G+V S TG V + K +V TTK F I+VSFG
Sbjct: 271 KSKGLQVNFPGLDPDAKSTAIFYSFARGPGAVMSVFTGDVEVSKTIVNTTKLFEISVSFG 330
Query: 294 SVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDADDLISDLDIA 142
+V SLISMP +MSHASI EVR+ARGL+EDL+RI GIE+ DDL +DL+ A
Sbjct: 331 AVNSLISMPAYMSHASIKKEVRDARGLSEDLIRICVGIENVDDLKADLENA 381
>sp|O05394|MCCB_BACSU Cystathionine gamma-lyase OS=Bacillus subtilis GN=mccB
PE=1 SV=1
Length = 379
Score = 178 bits (449), Expect = 2e-043
Identities = 87/198 (43%), Positives = 135/198 (68%), Gaps = 1/198 (0%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+S P+YQ +T+KQP A ++ Y+Y+R+ NPTR ALE+L+ +L+ + + F+SGMAA+
Sbjct: 20 AVSVPIYQVSTYKQPKAGQHTGYEYSRTANPTRTALEALVTELESGEAGYAFSSGMAAIT 79
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVNE*HN*FR-GVAAAIGPRTKLVW 851
AV L SGD +V DD+YGG+ R+++ V+ R G+ R V AI P TK ++
Sbjct: 80 AVMMLFNSGDHVVLTDDVYGGTYRVMTKVLNRLGIESTFVDTSSREEVEKAIRPNTKAIY 139
Query: 850 LESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFIAG 671
+E+PTNP +I+D+ +A++A G LL+VDN+ +P +PL LGADIV+HSATK++ G
Sbjct: 140 IETPTNPLLKITDLTLMADIAKKAGVLLIVDNTFNTPYFQQPLTLGADIVLHSATKYLGG 199
Query: 670 HSDLMGGCAFCKRRKIGK 617
HSD++GG +++G+
Sbjct: 200 HSDVVGGLVVTASKELGE 217
Score = 156 bits (392), Expect = 7e-037
Identities = 80/167 (47%), Positives = 109/167 (65%)
Frame = -3
Query: 651 GVLSVKGEKLAKELYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLFT 472
G++ ++L +EL+F+QNS G L P D WL +RGIKT+ LR+E +NARKIA +L
Sbjct: 206 GLVVTASKELGEELHFVQNSTGGVLGPQDSWLLMRGIKTLGLRMEAIDQNARKIASFLEN 265
Query: 471 HPRVKQVYHAGLPDHPGHHLHFFQAKGAGSVFSFITGSVALFKHLVETTKYFSIAVSFGS 292
HP V+ +Y+ G +HPGH L Q G G + SF GS + K F+IA S G+
Sbjct: 266 HPAVQTLYYPGSSNHPGHELAKTQGAGFGGMISFDIGSEERVDAFLGNLKLFTIAESLGA 325
Query: 291 VKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDADDLISDL 151
V+SLIS+P M+HASIP E R G+T+ L+RIS GIEDA+DL+ D+
Sbjct: 326 VESLISVPARMTHASIPRERRLELGITDGLIRISVGIEDAEDLLEDI 372
>sp|O31632|METC_BACSU Cystathionine beta-lyase metC OS=Bacillus subtilis GN=metC
PE=1 SV=1
Length = 390
Score = 175 bits (442), Expect = 1e-042
Identities = 88/198 (44%), Positives = 130/198 (65%), Gaps = 1/198 (0%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+S P+ +TF Q S E G YDY+RSG PTR ALE +A L+ R F F+SGMAA++
Sbjct: 25 AVSVPIQHASTFHQSSFEEFGAYDYSRSGTPTRTALEETIAALEGGTRGFAFSSGMAAIS 84
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVNE*HN*FRG-VAAAIGPRTKLVW 851
LL GD ++ +D+YGG+ R+++ V+ R G+ R VA +I P TK+++
Sbjct: 85 TAFLLLSQGDHVLVTEDVYGGTFRMVTEVLTRFGIEHTFVDMTDRNEVARSIKPNTKVIY 144
Query: 850 LESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFIAG 671
+E+P+NP I+DI+ + ++A G L +DN+ M+P L RPL+LG DIV+HSATKF++G
Sbjct: 145 METPSNPTLGITDIKAVVQLAKENGCLTFLDNTFMTPALQRPLDLGVDIVLHSATKFLSG 204
Query: 670 HSDLMGGCAFCKRRKIGK 617
HSD++ G A K ++GK
Sbjct: 205 HSDVLSGLAAVKDEELGK 222
Score = 163 bits (410), Expect = 6e-039
Identities = 82/173 (47%), Positives = 115/173 (66%)
Frame = -3
Query: 654 AGVLSVKGEKLAKELYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLF 475
+G+ +VK E+L K+LY LQN+ G+ L DCWL LRG+KT+ +R+EK + A+++A +
Sbjct: 210 SGLAAVKDEELGKQLYKLQNAFGAVLGVQDCWLVLRGLKTLQVRLEKASQTAQRLAEFFQ 269
Query: 474 THPRVKQVYHAGLPDHPGHHLHFFQAKGAGSVFSFITGSVALFKHLVETTKYFSIAVSFG 295
HP VK+VY+ GL DHPG H Q+ GAG+V SF S K LVE AVS G
Sbjct: 270 KHPAVKRVYYPGLADHPGAETHKSQSTGAGAVLSFELESKEAVKKLVENVSLPVFAVSLG 329
Query: 294 SVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDADDLISDLDIAFR 136
+V+S++S P MSHA++P E RE RG+T+ L+R+S G+E ADDL D + A +
Sbjct: 330 AVESILSYPATMSHAAMPKEEREKRGITDGLLRLSVGVEHADDLEHDFEQALK 382
>sp|Q83A83|METC_COXBU Cystathionine beta-lyase OS=Coxiella burnetii GN=metC PE=1
SV=1
Length = 387
Score = 168 bits (425), Expect = 1e-040
Identities = 92/219 (42%), Positives = 134/219 (61%), Gaps = 13/219 (5%)
Frame = -2
Query: 1276 NVREEASVATLLMNLDNKFDPF-DAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDAL 1100
N +++ + T +++ K DP A+ TP+Y +T+ Q S + Y+Y+RS NPTR A
Sbjct: 4 NNNKKSHIDTRVIHAGQKPDPLTGAVMTPIYTASTYAQKSPGVHQGYEYSRSQNPTRFAY 63
Query: 1099 ESLLAKLDKADRAFCFTSGMAALAAVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVV 920
E +A L+ F F SGMAA A + LL+ GD +V DD+YGGS RL NV RS +
Sbjct: 64 ERCVADLESGQHGFAFASGMAATATILELLQPGDHVVVMDDVYGGSYRLFENVRKRSAGL 123
Query: 919 -------VNE*HN*FRGVAAAIGPRTKLVWLESPTNPRQQISDIRKIAEMAHAQGALLLV 761
+E V A+ +TK++W+ESP+NPR +I D+ KIAE+A + + +
Sbjct: 124 SFSFVDFTDE-----NKVREAVTAKTKMLWVESPSNPRLKIVDLAKIAEIAKEKNIIAVA 178
Query: 760 DNSIMSPVLSRPLELGADIVMHSATKFIAGHSDLMGGCA 644
DN+ +P++ RPLELG DIV HSATK++ GHSD++GG A
Sbjct: 179 DNTFATPIIQRPLELGFDIVTHSATKYLNGHSDIIGGVA 217
>sp|P0C2T9|METC_LACLC Cystathionine beta-lyase OS=Lactococcus lactis subsp.
cremoris GN=metC PE=1 SV=1
Length = 380
Score = 168 bits (425), Expect = 1e-040
Identities = 83/188 (44%), Positives = 128/188 (68%), Gaps = 3/188 (1%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+S P+YQT+T+KQ + Y+Y+RSGNPTR ALE L+A L+ + F F+SG+A +
Sbjct: 21 AVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIH 80
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVN--E*HN*FRGVAAAIGPRTKLV 854
AV L +GD ++ DD+YGG+ RL+ V+ ++G++ + + N + AA TK V
Sbjct: 81 AVLSLFSAGDHIILADDVYGGTFRLVDKVLTKTGIIYDLVDLSN-LEDLKAAFKAETKAV 139
Query: 853 WLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFIA 674
+ E+P+NP ++ DI++I+ +A A AL LVDN+ +P L +P+ LGADIV+HSATK++
Sbjct: 140 YFETPSNPLLKVLDIKEISSIAKAHNALTLVDNTFATPYLQQPIALGADIVLHSATKYLG 199
Query: 673 GHSDLMGG 650
GHSD++ G
Sbjct: 200 GHSDVVAG 207
>sp|P0A4K2|METC_LACLA Cystathionine beta-lyase OS=Lactococcus lactis subsp.
lactis GN=metC PE=3 SV=1
Length = 380
Score = 168 bits (423), Expect = 2e-040
Identities = 83/201 (41%), Positives = 132/201 (65%), Gaps = 3/201 (1%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+S P+YQT+T+KQ + Y+Y+RSGNPTR ALE L+A L+ + F F+SG+A +
Sbjct: 21 AVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIH 80
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVN--E*HN*FRGVAAAIGPRTKLV 854
AV L +GD ++ DD+YGG+ RL+ V+ ++G++ + + N + AA TK +
Sbjct: 81 AVLSLFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSN-LDDLKAAFKEETKAI 139
Query: 853 WLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFIA 674
+ E+P+NP ++ DI++I+ +A A AL LVDN+ +P L +P+ LGADIV+HSATK++
Sbjct: 140 YFETPSNPLLKVLDIKEISAIAKAHDALTLVDNTFATPYLQQPIALGADIVLHSATKYLG 199
Query: 673 GHSDLMGGCAFCKRRKIGKGI 611
GHSD++ G +++ I
Sbjct: 200 GHSDVVAGLVTTNSKELASEI 220
>sp|A2RM21|METC_LACLM Cystathionine beta-lyase OS=Lactococcus lactis subsp.
cremoris (strain MG1363) GN=metC PE=1 SV=1
Length = 380
Score = 168 bits (423), Expect = 2e-040
Identities = 83/201 (41%), Positives = 132/201 (65%), Gaps = 3/201 (1%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+S P+YQT+T+KQ + Y+Y+RSGNPTR ALE L+A L+ + F F+SG+A +
Sbjct: 21 AVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIH 80
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVN--E*HN*FRGVAAAIGPRTKLV 854
AV L +GD ++ DD+YGG+ RL+ V+ ++G++ + + N + AA TK +
Sbjct: 81 AVLSLFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSN-LDDLKAAFKEETKAI 139
Query: 853 WLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFIA 674
+ E+P+NP ++ DI++I+ +A A AL LVDN+ +P L +P+ LGADIV+HSATK++
Sbjct: 140 YFETPSNPLLKVLDIKEISAIAKAHDALTLVDNTFATPYLQQPIALGADIVLHSATKYLG 199
Query: 673 GHSDLMGGCAFCKRRKIGKGI 611
GHSD++ G +++ I
Sbjct: 200 GHSDVVAGLVTTNSKELASEI 220
>sp|Q55DV9|CGL_DICDI Cystathionine gamma-lyase OS=Dictyostelium discoideum
GN=cysA PE=1 SV=1
Length = 387
Score = 166 bits (420), Expect = 4e-040
Identities = 85/188 (45%), Positives = 122/188 (64%), Gaps = 2/188 (1%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPS-AIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAAL 1031
A+ P+ + TF QPS + + YDY+RSGNPTR A E +A + A A F SG+A L
Sbjct: 26 AVIVPISLSTTFLQPSPGVLHSEYDYSRSGNPTRKAFEECIAACENAKYALSFASGLATL 85
Query: 1030 AAVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVNE*H-N*FRGVAAAIGPRTKLV 854
+THLLKSGDE+++ DD+YGG+ R + V + + + + A +T+LV
Sbjct: 86 TTITHLLKSGDEVISIDDVYGGTRRYFTRVAANFDLKFSFVDLSTLDDLKNAFTDKTRLV 145
Query: 853 WLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFIA 674
W+E+PTNP +++DI+ +A+ H++GA L+VDN+ MSP PL+LGADIVMHS TK+I
Sbjct: 146 WIETPTNPLLKVADIKAVADYVHSRGATLVVDNTFMSPYFQNPLDLGADIVMHSVTKYIN 205
Query: 673 GHSDLMGG 650
GHSD + G
Sbjct: 206 GHSDCVMG 213
>sp|O31631|METB_BACSU Cystathionine gamma-synthase OS=Bacillus subtilis GN=metB
PE=1 SV=1
Length = 373
Score = 166 bits (420), Expect = 4e-040
Identities = 89/217 (41%), Positives = 130/217 (59%), Gaps = 6/217 (2%)
Frame = -2
Query: 1255 VATLLMNLDNKFDPF-DAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKL 1079
V T L + N+ D +S P+Y + ++ E+ +DY R+ NPTR +E +A L
Sbjct: 5 VETKLAQIGNRSDEVTGTVSAPIYLSTAYRHRGIGESTGFDYVRTKNPTRQLVEDAIANL 64
Query: 1078 DKADRAFCFTSGMAALAAVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVNE*HN* 899
+ R F+SGMAA+ + L KSGDEL+ DLYGG+ RL N + G+ + ++
Sbjct: 65 ENGARGLAFSSGMAAIQTIMALFKSGDELIVSSDLYGGTYRLFENEWKKYGLTFH--YDD 122
Query: 898 FRG---VAAAIGPRTKLVWLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSR 728
F + + I P TK V++E+PTNP Q +DI IA + G LL+VDN+ +PVL R
Sbjct: 123 FSDEDCLRSKITPNTKAVFVETPTNPLMQEADIEHIARITKEHGLLLIVDNTFYTPVLQR 182
Query: 727 PLELGADIVMHSATKFIAGHSDLMGGCAFCKRRKIGK 617
PLELGADIV+HSATK++ GH+DL+ G K ++G+
Sbjct: 183 PLELGADIVIHSATKYLGGHNDLLAGLVVVKDERLGE 219
>sp|P56069|METB_HELPY Cystathionine gamma-synthase OS=Helicobacter pylori
GN=metB PE=3 SV=1
Length = 380
Score = 162 bits (409), Expect = 8e-039
Identities = 82/189 (43%), Positives = 127/189 (67%), Gaps = 5/189 (2%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+S P+YQT+T++Q + + Y+Y+RSGNPTR ALE L+A L+ + F F SG+A +
Sbjct: 20 AVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIH 79
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGV---VVNE*HN*FRGVAAAIGPRTKL 857
AV LL+SGD ++ GDD+YGG+ RL + V+ ++G+ +++ + + AI P TK
Sbjct: 80 AVFSLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSCTIIDT--SDISQIKKAIKPNTKA 137
Query: 856 VWLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFI 677
++LE+P+NP +I+D+ + A +A G L +VDN+ +P PL LGADIV HS TK++
Sbjct: 138 LYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFATPYYQNPLLLGADIVAHSGTKYL 197
Query: 676 AGHSDLMGG 650
GHSD++ G
Sbjct: 198 GGHSDVVAG 206
>sp|P24601|METB_HERAU Probable cystathionine gamma-synthase (Fragment)
OS=Herpetosiphon aurantiacus GN=metB PE=3 SV=1
Length = 319
Score = 160 bits (403), Expect = 4e-038
Identities = 81/192 (42%), Positives = 120/192 (62%), Gaps = 11/192 (5%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+ P+YQT+T+ Q ++ Y+Y+R+ NPTR AL++ LA L++A A F SG+ A
Sbjct: 22 AVIVPIYQTSTYAQRGVGDHTGYEYSRTDNPTRTALQTCLAALEEAKHALVFASGLGAST 81
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVNE*HN*F------RGVAAAIGPR 866
+ +LK+GD ++ GDD+YGG+ RL V+ G+ + F V AAI P
Sbjct: 82 TLMLMLKAGDHVICGDDVYGGTYRLFQRVMTEHGLSFD-----FIDMADPEAVRAAIKPN 136
Query: 865 TKLVWLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSAT 686
T+L+WLE+PTNP +++ I I +A G +VDN+ SP RP+ LGAD+V+HS T
Sbjct: 137 TRLIWLETPTNPLLKLAPIAAITRVAREHGIWTIVDNTFASPYNQRPITLGADMVLHSTT 196
Query: 685 KFIAGHSDLMGG 650
K+I GHSD++GG
Sbjct: 197 KYIGGHSDVVGG 208
>sp|P44502|METB_HAEIN Cystathionine gamma-synthase OS=Haemophilus influenzae
GN=metB PE=3 SV=1
Length = 369
Score = 158 bits (397), Expect = 2e-037
Identities = 86/220 (39%), Positives = 133/220 (60%), Gaps = 7/220 (3%)
Frame = -2
Query: 1267 EEASVATLLMNLDNKFDP-FDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESL 1091
++ ++ TLL N+ D A+S P++ + + E+ +DYTR+ NPTR LE
Sbjct: 3 QQYAIDTLLAQAGNRSDERTGAVSAPIFLSTAYGHCGIGESTGFDYTRTKNPTRTVLEET 62
Query: 1090 LAKLDKADRAFCFTSGMAALAAVTHLLKSGDELVAGDDLYGGSDRLL----SNVVPRSGV 923
+AKL+ DR F F+SGMAA+ + L + DE + D+YGG+ RLL N V
Sbjct: 63 IAKLENGDRGFAFSSGMAAIQVLMTLFTAPDEWIVSSDVYGGTYRLLDFSYKNNNSVKPV 122
Query: 922 VVNE*HN*FRGVAAAIGPRTKLVWLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMS 743
VN + AAI P TK +++E+P+NP + D+ +IA++A +L+VDN+ ++
Sbjct: 123 YVNTAS--ASAIEAAINPNTKAIFIETPSNPLMEECDVVEIAKLAKKHNLMLIVDNTFLT 180
Query: 742 PVLSRPLELGADIVMHSATKFIAGHSDLMGGCAFCKRRKI 623
PVLSRPL+LGAD+V+HS TK+IAGH+D + G K +++
Sbjct: 181 PVLSRPLDLGADVVIHSGTKYIAGHNDALVGLIVAKGQEL 220
>sp|Q9ZMW7|METB_HELPJ Cystathionine gamma-synthase OS=Helicobacter pylori J99
GN=metB PE=3 SV=1
Length = 380
Score = 158 bits (397), Expect = 2e-037
Identities = 79/189 (41%), Positives = 125/189 (66%), Gaps = 5/189 (2%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALA 1028
A+S P+YQT+T++Q + + Y+Y+RSGNPTR ALE L+A L+ + F F SG+A +
Sbjct: 20 AVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIH 79
Query: 1027 AVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGV---VVNE*HN*FRGVAAAIGPRTKL 857
AV LL+SGD ++ GDD+YGG+ RL + V+ ++G+ +++ + + AI P TK
Sbjct: 80 AVFSLLQSGDHVLLGDDVYGGNFRLFNKVLVKNGLSCTIIDT--SDLSQIKKAIKPNTKA 137
Query: 856 VWLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFI 677
++LE+P+NP +I+D+ + A +A L +VDN+ +P PL LG DIV H+ TK++
Sbjct: 138 LYLETPSNPLLKITDLAQCASVAKEHNLLTIVDNTFATPYCQNPLLLGTDIVAHNGTKYL 197
Query: 676 AGHSDLMGG 650
GHSD++ G
Sbjct: 198 GGHSDVVAG 206
>sp|P66876|METB_MYCBO Cystathionine gamma-synthase OS=Mycobacterium bovis
GN=metB PE=3 SV=1
Length = 388
Score = 157 bits (395), Expect = 3e-037
Identities = 87/189 (46%), Positives = 121/189 (64%), Gaps = 3/189 (1%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIE-NGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAAL 1031
A++ P+Y ++TF Q G ++Y R+GNPTR ALE+ LA +++ A F+SGMAA
Sbjct: 31 AVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEGAFARAFSSGMAAT 90
Query: 1030 -AAVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVNE*H-N*FRGVAAAIGPRTKL 857
A+ +L+ GD +V DD YGG+ RL+ V R V V AAI PRT+L
Sbjct: 91 DCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTRWDVQYTPVRLADLDAVGAAITPRTRL 150
Query: 856 VWLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFI 677
+W+E+PTNP I+DI IAE+ + A +LVDN+ SP L +PL LGAD+V+HS TK+I
Sbjct: 151 IWVETPTNPLLSIADITAIAELGTDRSAKVLVDNTFASPALQQPLRLGADVVLHSTTKYI 210
Query: 676 AGHSDLMGG 650
GHSD++GG
Sbjct: 211 GGHSDVVGG 219
>sp|P66875|METB_MYCTU Cystathionine gamma-synthase OS=Mycobacterium tuberculosis
GN=metB PE=3 SV=1
Length = 388
Score = 157 bits (395), Expect = 3e-037
Identities = 87/189 (46%), Positives = 121/189 (64%), Gaps = 3/189 (1%)
Frame = -2
Query: 1207 AMSTPLYQTATFKQPSAIE-NGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAAL 1031
A++ P+Y ++TF Q G ++Y R+GNPTR ALE+ LA +++ A F+SGMAA
Sbjct: 31 AVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEGAFARAFSSGMAAT 90
Query: 1030 -AAVTHLLKSGDELVAGDDLYGGSDRLLSNVVPRSGVVVNE*H-N*FRGVAAAIGPRTKL 857
A+ +L+ GD +V DD YGG+ RL+ V R V V AAI PRT+L
Sbjct: 91 DCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTRWDVQYTPVRLADLDAVGAAITPRTRL 150
Query: 856 VWLESPTNPRQQISDIRKIAEMAHAQGALLLVDNSIMSPVLSRPLELGADIVMHSATKFI 677
+W+E+PTNP I+DI IAE+ + A +LVDN+ SP L +PL LGAD+V+HS TK+I
Sbjct: 151 IWVETPTNPLLSIADITAIAELGTDRSAKVLVDNTFASPALQQPLRLGADVVLHSTTKYI 210
Query: 676 AGHSDLMGG 650
GHSD++GG
Sbjct: 211 GGHSDVVGG 219
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,819,846,109
Number of Sequences: 518415
Number of Extensions: 95819846109
Number of Successful Extensions: 619733697
Number of sequences better than 0.0: 0
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