BLASTX 7.6.2
Query= UN22746 /QuerySize=1740
(1739 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P87145|VAC14_SCHPO Protein VAC14 homolog OS=Schizosaccharomyc... 223 4e-057
sp|Q5ZIW5|VAC14_CHICK Protein VAC14 homolog OS=Gallus gallus GN=... 196 5e-049
sp|Q68F38|VAC14_XENLA Protein VAC14 homolog OS=Xenopus laevis GN... 195 9e-049
sp|Q08AM6|VAC14_HUMAN Protein VAC14 homolog OS=Homo sapiens GN=V... 195 1e-048
sp|Q80WQ2|VAC14_MOUSE Protein VAC14 homolog OS=Mus musculus GN=V... 194 2e-048
sp|Q80W92|VAC14_RAT Protein VAC14 homolog OS=Rattus norvegicus G... 194 2e-048
sp|A2VE70|VAC14_BOVIN Protein VAC14 homolog OS=Bos taurus GN=VAC... 193 4e-048
sp|Q66L58|VAC14_DANRE Protein VAC14 homolog OS=Danio rerio GN=va... 192 8e-048
sp|Q06708|VAC14_YEAST Vacuole morphology and inheritance protein... 161 2e-038
>sp|P87145|VAC14_SCHPO Protein VAC14 homolog OS=Schizosaccharomyces pombe
GN=SPBC25H2.03 PE=2 SV=1
Length = 811
Score = 223 bits (567), Expect = 4e-057
Identities = 130/296 (43%), Positives = 187/296 (63%), Gaps = 13/296 (4%)
Frame = -3
Query: 1722 ETNEELRSIHVEPSDGFDVGAILSVARRQLSSDNEATRIEALNWISTLLNKHRTEVLCFL 1543
ETN + S+ V D +++ V ++ LS+DNE TR+ AL W+ L + +++
Sbjct: 422 ETNNKDNSLSV------DFRSLIEVLQKLLSNDNEETRLCALEWVLLLQRRTGGKLINMH 475
Query: 1542 NDIFDTLLKALSDSSDDVVLLVLEVHAGVAKDPQYFRHLIVF---LVHNFRADNSLLERR 1372
+ IF TLL LSD SD VV LE+ A +A + +L+ F L+ F D L R
Sbjct: 476 DPIFQTLLLQLSDPSDLVVSRTLELLAHIAISHKSV-NLVPFLKSLLQMFAEDRKFLNSR 534
Query: 1371 GAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTMVQALNLILLTAPELSKLRGLLKG 1192
G +I+R+LC ++ ERVY + ILE E+NL+ AS MV+ LN L TAPEL LR LK
Sbjct: 535 GNLIIRQLCNYIEGERVYTSFAGILETEENLELASIMVEVLNNNLFTAPELYDLRKKLKQ 594
Query: 1191 SLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQHASVVIQSLVEEDINVKFLVQLDK 1012
S + ++F LY +WCH+ +A+ SLCLL+Q Y+HA+ ++ E + N+ L+QLDK
Sbjct: 595 SAPKLQ--NIFTTLYTAWCHNSIAVFSLCLLSQNYEHAANLLSVFAEIEFNIDMLIQLDK 652
Query: 1011 LIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLLPQQSAAFKILRTRLKTVPT 844
L++L+E+P+FTY+RLQLLEP +Y +L K LYG+LMLLP QS+AF+ LR RL+ T
Sbjct: 653 LVQLIESPVFTYMRLQLLEPEKYPYLHKALYGILMLLP-QSSAFRTLRDRLQCSST 707
>sp|Q5ZIW5|VAC14_CHICK Protein VAC14 homolog OS=Gallus gallus GN=VAC14 PE=2
SV=1
Length = 780
Score = 196 bits (497), Expect = 5e-049
Identities = 107/248 (43%), Positives = 157/248 (63%), Gaps = 9/248 (3%)
Frame = -3
Query: 1440 YFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTM 1261
YF ++ L+ F ++ LLE RGA I+R+LC+LL+ E ++ ++ IL E++L FASTM
Sbjct: 524 YFYKFMINLLKRFSSERKLLETRGAFIIRQLCLLLNTENIFHSMADILLREEDLKFASTM 583
Query: 1260 VQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQH 1081
V LN ILLT+ EL +LR LK L E ++LF LY SWCH+P+ +SLC L Q Y+H
Sbjct: 584 VHTLNTILLTSSELFQLRNQLK-DLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYKH 642
Query: 1080 ASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLL 901
A +IQ + ++ V FL ++DKL++L+E PIFTYLRLQLL+ +L+K LYGLLMLL
Sbjct: 643 AYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLL 702
Query: 900 PQQSAAFKILRTRLKTVPTYSF--SGGGDQISR-----ASSGVPFSQYMNHHEDDDAEEI 742
P QS+AF++L RL+ VP S G + S ASS + +++ + H + ++ +
Sbjct: 703 P-QSSAFQLLSHRLQCVPNPELMQSADGSRASASSRRPASSTIDYTELLQHFDKVQSKHL 761
Query: 741 NITSSHQG 718
+ G
Sbjct: 762 EVRHQRAG 769
>sp|Q68F38|VAC14_XENLA Protein VAC14 homolog OS=Xenopus laevis GN=vac14 PE=2
SV=1
Length = 782
Score = 195 bits (495), Expect = 9e-049
Identities = 112/248 (45%), Positives = 155/248 (62%), Gaps = 9/248 (3%)
Frame = -3
Query: 1440 YFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTM 1261
YF +V L+ F + LLE RGA I+R+LC+LL+AE ++ ++ IL E++L FASTM
Sbjct: 526 YFHRFMVNLLKRFSNERKLLEIRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTM 585
Query: 1260 VQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQH 1081
VQ LN ILLT+ EL +LR LK L E +LF LY SWCH+P+A +SLC L Q YQH
Sbjct: 586 VQNLNSILLTSSELFQLRSQLK-DLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQH 644
Query: 1080 ASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLL 901
A +IQ + ++ V FL ++DKL++L+E PIFTYLRLQLL+ +L++ LYGLLMLL
Sbjct: 645 AYNLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENNPYLIRALYGLLMLL 704
Query: 900 PQQSAAFKILRTRLKTVPTYSFSGGG---DQISRASSGVP----FSQYMNHHEDDDAEEI 742
P QS+AF++L RL+ VP G ++ SRA P + + + H E + +
Sbjct: 705 P-QSSAFQLLSHRLQCVPNPQLMRPGHKQEESSRAPKEDPARIDYVELLQHFEKVQNKHL 763
Query: 741 NITSSHQG 718
I G
Sbjct: 764 EIRHQRSG 771
>sp|Q08AM6|VAC14_HUMAN Protein VAC14 homolog OS=Homo sapiens GN=VAC14 PE=1 SV=1
Length = 782
Score = 195 bits (494), Expect = 1e-048
Identities = 106/248 (42%), Positives = 154/248 (62%), Gaps = 9/248 (3%)
Frame = -3
Query: 1440 YFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTM 1261
YF ++ L+ F ++ LLE RG I+R+LC+LL+AE ++ ++ IL E++L FASTM
Sbjct: 526 YFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTM 585
Query: 1260 VQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQH 1081
V ALN ILLT+ EL +LR LK L E ++LF LY SWCH+P+ +SLC L Q Y+H
Sbjct: 586 VHALNTILLTSTELFQLRNQLK-DLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRH 644
Query: 1080 ASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLL 901
A +IQ + ++ V FL ++DKL++L+E PIFTYLRLQLL+ +L+K LYGLLMLL
Sbjct: 645 AYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLL 704
Query: 900 PQQSAAFKILRTRLKTVPTYSFSGGGDQISRA-------SSGVPFSQYMNHHEDDDAEEI 742
P QS+AF++L RL+ VP D + A S + +++ + H E + +
Sbjct: 705 P-QSSAFQLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQHFEKVQNKHL 763
Query: 741 NITSSHQG 718
+ G
Sbjct: 764 EVRHQRSG 771
>sp|Q80WQ2|VAC14_MOUSE Protein VAC14 homolog OS=Mus musculus GN=Vac14 PE=1 SV=1
Length = 782
Score = 194 bits (492), Expect = 2e-048
Identities = 105/248 (42%), Positives = 153/248 (61%), Gaps = 9/248 (3%)
Frame = -3
Query: 1440 YFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTM 1261
YF ++ L+ F ++ LLE RG I+R+LC+LL+AE ++ ++ IL E++L FASTM
Sbjct: 526 YFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTM 585
Query: 1260 VQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQH 1081
V LN ILLT+ EL +LR LK L E ++LF LY SWCH+P+ +SLC L Q Y+H
Sbjct: 586 VHTLNTILLTSTELFQLRNQLK-DLQTPESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRH 644
Query: 1080 ASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLL 901
A +IQ + ++ V FL ++DKL++L+E PIFTYLRLQLL+ +L+K LYGLLMLL
Sbjct: 645 AYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLL 704
Query: 900 PQQSAAFKILRTRLKTVPTYSFSGGGDQISRA-------SSGVPFSQYMNHHEDDDAEEI 742
P QS+AF++L RL+ VP D + A S + +++ + H E + +
Sbjct: 705 P-QSSAFQLLSHRLQCVPNPELLQTEDCLKAAPKSQKGDSPSIDYTELLQHFEKVQKQHL 763
Query: 741 NITSSHQG 718
+ G
Sbjct: 764 EVRHQRSG 771
>sp|Q80W92|VAC14_RAT Protein VAC14 homolog OS=Rattus norvegicus GN=Vac14 PE=1
SV=1
Length = 783
Score = 194 bits (492), Expect = 2e-048
Identities = 105/248 (42%), Positives = 153/248 (61%), Gaps = 9/248 (3%)
Frame = -3
Query: 1440 YFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTM 1261
YF ++ L+ F ++ LLE RG I+R+LC+LL+AE ++ ++ IL E++L FASTM
Sbjct: 527 YFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTM 586
Query: 1260 VQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQH 1081
V LN ILLT+ EL +LR LK L E ++LF LY SWCH+P+ +SLC L Q Y+H
Sbjct: 587 VHTLNTILLTSTELFQLRNQLK-DLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRH 645
Query: 1080 ASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLL 901
A +IQ + ++ V FL ++DKL++L+E PIFTYLRLQLL+ +L+K LYGLLMLL
Sbjct: 646 AYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLMKALYGLLMLL 705
Query: 900 PQQSAAFKILRTRLKTVPTYSFSGGGDQISRA-------SSGVPFSQYMNHHEDDDAEEI 742
P QS+AF++L RL+ VP D + A S + +++ + H E + +
Sbjct: 706 P-QSSAFQLLSHRLQCVPNPELLQTEDCLKAAPKSQKGDSPSIDYTELLQHFEKVQKQHL 764
Query: 741 NITSSHQG 718
+ G
Sbjct: 765 EVRHQRSG 772
>sp|A2VE70|VAC14_BOVIN Protein VAC14 homolog OS=Bos taurus GN=VAC14 PE=2 SV=1
Length = 783
Score = 193 bits (489), Expect = 4e-048
Identities = 106/248 (42%), Positives = 152/248 (61%), Gaps = 9/248 (3%)
Frame = -3
Query: 1440 YFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTM 1261
YF ++ L+ F ++ LLE RGA I+R+LC+LL AE ++ ++ IL E++L FASTM
Sbjct: 527 YFYKFMINLLKRFSSERKLLEVRGAFIIRQLCLLLHAESIFHSMADILLREEDLTFASTM 586
Query: 1260 VQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQH 1081
V LN ILLT+ EL +LR LK L E ++LF LY SWCH P+ +SLC L Q Y+H
Sbjct: 587 VHTLNTILLTSTELFQLRNQLK-DLKTPESRNLFCCLYRSWCHKPVTTVSLCFLTQNYRH 645
Query: 1080 ASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLL 901
A +IQ + ++ V FL ++DKL++L+E PIFTYLRLQLL+ +L+K LYGLLMLL
Sbjct: 646 AYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKSNPYLIKALYGLLMLL 705
Query: 900 PQQSAAFKILRTRLKTVPTYSFSGGGDQISRA-------SSGVPFSQYMNHHEDDDAEEI 742
P QS+AF++L RL+ VP D + A S + +++ + H E + +
Sbjct: 706 P-QSSAFQLLSHRLQCVPNPELLQTEDGLKAAPKSQKADSPSIDYAELLQHFERVQKKHL 764
Query: 741 NITSSHQG 718
+ G
Sbjct: 765 EVRHQRSG 772
>sp|Q66L58|VAC14_DANRE Protein VAC14 homolog OS=Danio rerio GN=vac14 PE=2 SV=1
Length = 771
Score = 192 bits (487), Expect = 8e-048
Identities = 102/198 (51%), Positives = 138/198 (69%), Gaps = 2/198 (1%)
Frame = -3
Query: 1440 YFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRELSTILEGEDNLDFASTM 1261
YF ++ L+ F + LLE RGA I+R+LC+LL AE ++ ++ IL E++L FASTM
Sbjct: 516 YFYKFMINLLKRFSLERKLLEMRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTM 575
Query: 1260 VQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCHSPMAIISLCLLAQAYQH 1081
VQ LN ILLT+ EL +LR LK L +E LF LY SWCH+P+A +SLC L Q Y+H
Sbjct: 576 VQTLNTILLTSAELFQLRNQLK-DLRTQESCALFCCLYRSWCHNPVATVSLCFLTQNYRH 634
Query: 1080 ASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEPGRYTWLLKTLYGLLMLL 901
A +IQ + ++ V FL+++DKL++L+E+PIFTYLRLQLL+ +L+K LYGLLMLL
Sbjct: 635 AYDLIQKFGDLEVTVDFLMEVDKLVQLIESPIFTYLRLQLLDVEHNPYLIKALYGLLMLL 694
Query: 900 PQQSAAFKILRTRLKTVP 847
P QS AF++L RL VP
Sbjct: 695 P-QSQAFQLLSHRLSCVP 711
>sp|Q06708|VAC14_YEAST Vacuole morphology and inheritance protein 14
OS=Saccharomyces cerevisiae GN=VAC14 PE=1 SV=1
Length = 880
Score = 161 bits (406), Expect = 2e-038
Identities = 94/274 (34%), Positives = 159/274 (58%), Gaps = 7/274 (2%)
Frame = -3
Query: 1665 GAILSVARRQLSSDNEATRIEALNWISTLLNKHRTEVLCFLNDIFDTLLKALSDSSDDVV 1486
G I++ Q +I L+W+ + +K ++L + +F TLLK+LS+ ++
Sbjct: 479 GPIVNSLTLQFFDSRIDAKIACLDWLILIYHKAPNQILKHNDSMFLTLLKSLSNRDSVLI 538
Query: 1485 LLVLEVHAGVAKD--PQYFRHLIVFLVHNFRADNSLLERRGAIIVRRLCVLLDAERVYRE 1312
L + + D Y R + L+ F+ D L++ R I+R++ L ERVY+
Sbjct: 539 EKALSLLQSLCSDSNDNYLRQFLQDLLTLFKRDTKLVKTRANFIMRQISSRLSPERVYKV 598
Query: 1311 LSTILEGEDNLDFASTMVQALNLILLTAPELSKLRGLLKGSLVNREGKDLFVALYASWCH 1132
+S+IL+ ++ F M+Q L+ L+T+PE+S LR L+ E F +L+ SWC
Sbjct: 599 ISSILDNYNDTTFVKMMIQILSTNLITSPEMSSLRNKLR----TCEDGMFFNSLFKSWCP 654
Query: 1131 SPMAIISLCLLAQAYQHASVVIQSLVEEDINVKFLVQLDKLIRLLETPIFTYLRLQLLEP 952
+P+++ISLC +A+ Y+ A V+Q+ ++ + LVQLD LI+L E+P+FT +RLQLLE
Sbjct: 655 NPVSVISLCFVAENYELAYTVLQTYANYELKLNDLVQLDILIQLFESPVFTRMRLQLLEQ 714
Query: 951 GRYTWLLKTLYGLLMLLPQQSAAFKILRTRLKTV 850
++ +L K L+G+LM++P QS AF+ L RL ++
Sbjct: 715 QKHPFLHKCLFGILMIIP-QSKAFETLNRRLNSL 747
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,819,846,109
Number of Sequences: 518415
Number of Extensions: 95819846109
Number of Successful Extensions: 619733697
Number of sequences better than 0.0: 0
|
