BLASTX 7.6.2
Query= UN22796 /QuerySize=1340
(1339 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O67550|EX53_AQUAE 5'-3' exonuclease OS=Aquifex aeolicus GN=aq... 99 6e-020
sp|Q04957|DPO1_BACCA DNA polymerase I OS=Bacillus caldotenax GN=... 96 7e-019
sp|O34996|DPO1_BACSU DNA polymerase I OS=Bacillus subtilis GN=po... 95 1e-018
sp|P52026|DPO1_BACST DNA polymerase I OS=Bacillus stearothermoph... 93 4e-018
sp|P0A551|DPO1_MYCBO DNA polymerase I OS=Mycobacterium bovis GN=... 90 4e-017
sp|P0A550|DPO1_MYCTU DNA polymerase I OS=Mycobacterium tuberculo... 90 4e-017
sp|Q59156|DPO1_ANATD DNA polymerase I OS=Anaerocellum thermophil... 87 2e-016
sp|O08307|DPO1_CHLAA DNA polymerase I OS=Chloroflexus aurantiacu... 83 4e-015
sp|P46835|DPO1_MYCLE DNA polymerase I OS=Mycobacterium leprae GN... 82 8e-015
sp|P43741|DPO1_HAEIN DNA polymerase I OS=Haemophilus influenzae ... 82 1e-014
sp|P59200|DPO1_STRR6 DNA polymerase I OS=Streptococcus pneumonia... 79 7e-014
sp|P59199|DPO1_STRPN DNA polymerase I OS=Streptococcus pneumonia... 78 1e-013
sp|Q9RLB6|DPO1_RICHE DNA polymerase I OS=Rickettsia helvetica GN... 77 2e-013
sp|P74933|DPO1_TREPA DNA polymerase I OS=Treponema pallidum GN=p... 77 3e-013
sp|Q92GB7|DPO1_RICCN DNA polymerase I OS=Rickettsia conorii GN=p... 77 3e-013
sp|Q1RH76|DPO1_RICBR DNA polymerase I OS=Rickettsia bellii (stra... 75 7e-013
sp|Q9RAA9|DPO1_RICFE DNA polymerase I OS=Rickettsia felis GN=pol... 74 2e-012
sp|Q9RLA0|DPO1_RICTY DNA polymerase I OS=Rickettsia typhi GN=pol... 74 3e-012
sp|O51498|DPO1_BORBU DNA polymerase I OS=Borrelia burgdorferi GN... 73 5e-012
sp|O05949|DPO1_RICPR DNA polymerase I OS=Rickettsia prowazekii G... 73 5e-012
>sp|O67550|EX53_AQUAE 5'-3' exonuclease OS=Aquifex aeolicus GN=aq_1628 PE=3
SV=1
Length = 289
Score = 99 bits (245), Expect = 6e-020
Identities = 59/185 (31%), Positives = 98/185 (52%), Gaps = 10/185 (5%)
Frame = +3
Query: 300 FLDVSPLCYEGNKPSSKAFGHWLSLFFSQVSLTDP--VIAVLDGEEGNKRRRELLPSYKA 473
F + PL P++ +G +L + FS + P ++ V D KR + K
Sbjct: 17 FFALPPLSTSKGFPTNAIYG-FLRMLFSLIKKERPQYLVVVFDAPAKTKREKIYADYKKQ 75
Query: 474 HRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASP 653
K P+P K ++++L +P++ L G+EADDV+A L E+ Q+G++ I SP
Sbjct: 76 RPKAPDPLKVQ---IPVIKEILKLAGIPLLELPGYEADDVIAYLAEKFSQKGFKVKIYSP 132
Query: 654 DKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVDGVPGI 833
DKD QL+SENV ++ P++D +T + ++ +PQ + ++GD+VD VPGI
Sbjct: 133 DKDLLQLVSENVLVINPMND----EVFTKERVIKKFGVEPQKIPDYLALVGDKVDNVPGI 188
Query: 834 QHVVP 848
+ V P
Sbjct: 189 EGVGP 193
>sp|Q04957|DPO1_BACCA DNA polymerase I OS=Bacillus caldotenax GN=polA PE=1 SV=1
Length = 877
Score = 96 bits (236), Expect = 7e-019
Identities = 56/197 (28%), Positives = 102/197 (51%), Gaps = 8/197 (4%)
Frame = +3
Query: 444 RRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQ 623
R E YK R+ P + P + ++L +P L+ +EADD++ TL +A Q
Sbjct: 66 RHEAFQEYKGGRQQTPPELSEQFP--LLRELLRAYRIPAYELENYEADDIIGTLAARAEQ 123
Query: 624 RGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIM 803
G+ + S D+D QL S +V + I + YT + +Y P+ + + +M
Sbjct: 124 EGFEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPEAVREKYGLTPEQIVDLKGLM 183
Query: 804 GDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESLLSAAAVRTVGRPYAQEALTKYADYL 983
GD+ D +PG VP G KTA+KL+R+ G++E++L A++ + +E L ++ +
Sbjct: 184 GDKSDNIPG----VPGIGEKTAVKLLRQFGTVENVL--ASIDEIKGEKLKETLRQHREMA 237
Query: 984 RRNYQVLALKRDVKVQI 1034
+ ++ A++RD V++
Sbjct: 238 LLSKKLAAIRRDAPVEL 254
>sp|O34996|DPO1_BACSU DNA polymerase I OS=Bacillus subtilis GN=polA PE=3 SV=1
Length = 880
Score = 95 bits (234), Expect = 1e-018
Identities = 62/225 (27%), Positives = 107/225 (47%), Gaps = 13/225 (5%)
Frame = +3
Query: 444 RRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQ 623
R YK R+ P + P F+ ++L + L+ +EADD++ TL + A +
Sbjct: 68 RHGTFKEYKGGRQKTPPELSEQMP--FIRELLDAYQISRYELEQYEADDIIGTLAKSAEK 125
Query: 624 RGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIM 803
G+ + S DKD QL ++ + I + FYT +H +Y P+ + + +M
Sbjct: 126 DGFEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLTPEQIIDMKGLM 185
Query: 804 GDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESLLSAAAVRTVGRPYAQEALTKYADYL 983
GD D +PG VP G KTA+KL+++ S+E LL ++ V +E L ++ D
Sbjct: 186 GDSSDNIPG----VPGVGEKTAIKLLKQFDSVEKLLE--SIDEVSGKKLKEKLEEFKDQA 239
Query: 984 RRNYQVLALKRDVKVQIEEEWLVERDTSNDSQVLSSF----FSTL 1106
+ ++ + D +++ L E N QV++ F F+TL
Sbjct: 240 LMSKELATIMTDAPIEVSVSGL-EYQGFNREQVIAIFKDLGFNTL 283
>sp|P52026|DPO1_BACST DNA polymerase I OS=Bacillus stearothermophilus GN=polA
PE=1 SV=2
Length = 876
Score = 93 bits (229), Expect = 4e-018
Identities = 58/213 (27%), Positives = 105/213 (49%), Gaps = 8/213 (3%)
Frame = +3
Query: 444 RRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQ 623
R E YK R+ P + P + ++L +P L +EADD++ T+ +A +
Sbjct: 66 RHETFQDYKGGRQQTPPELSEQFP--LLRELLKAYRIPAYELDHYEADDIIGTMAARAER 123
Query: 624 RGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIM 803
G+ + S D+D QL S V + I + YT + +Y P+ + + +M
Sbjct: 124 EGFAVKVISGDRDLTQLASPQVTVEITKKGITDIESYTPETVVEKYGLTPEQIVDLKGLM 183
Query: 804 GDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESLLSAAAVRTVGRPYAQEALTKYADYL 983
GD+ D +PG VP G KTA+KL+++ G++E++L A++ + +E L +Y D
Sbjct: 184 GDKSDNIPG----VPGIGEKTAVKLLKQFGTVENVL--ASIDEIKGEKLKENLRQYRDLA 237
Query: 984 RRNYQVLALKRDVKVQIEEEWLVERDTSNDSQV 1082
+ Q+ A+ RD V++ + +V + + V
Sbjct: 238 LLSKQLAAICRDAPVELTLDDIVYKGEDREKVV 270
>sp|P0A551|DPO1_MYCBO DNA polymerase I OS=Mycobacterium bovis GN=polA PE=3 SV=1
Length = 904
Score = 90 bits (221), Expect = 4e-017
Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 13/195 (6%)
Frame = +3
Query: 444 RRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQ 623
R + P YKA+R + P +++ + ++VL + V+ G EADD++ATL QA
Sbjct: 80 RLQRYPEYKANRSS-TPDEFAGQ-IDITKEVLGALGITVLSEPGFEADDLIATLATQAEN 137
Query: 624 RGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIM 803
GYR ++ + D+D QL+S++V ++ P + + +T + +Y P+ F +
Sbjct: 138 EGYRVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQYPDFAALR 197
Query: 804 GDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESLL-SAAAVR-TVGRPYAQEALTKYAD 977
GD D +PGI P G KTA K + ++GSL SL+ + AVR VG +AL
Sbjct: 198 GDPSDNLPGI----PGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVG-----DALRANLA 248
Query: 978 YLRRNYQVLALKRDV 1022
+ RN ++ L RDV
Sbjct: 249 SVVRNRELTDLVRDV 263
>sp|P0A550|DPO1_MYCTU DNA polymerase I OS=Mycobacterium tuberculosis GN=polA
PE=3 SV=1
Length = 904
Score = 90 bits (221), Expect = 4e-017
Identities = 64/195 (32%), Positives = 103/195 (52%), Gaps = 13/195 (6%)
Frame = +3
Query: 444 RRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQ 623
R + P YKA+R + P +++ + ++VL + V+ G EADD++ATL QA
Sbjct: 80 RLQRYPEYKANRSS-TPDEFAGQ-IDITKEVLGALGITVLSEPGFEADDLIATLATQAEN 137
Query: 624 RGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIM 803
GYR ++ + D+D QL+S++V ++ P + + +T + +Y P+ F +
Sbjct: 138 EGYRVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQYPDFAALR 197
Query: 804 GDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESLL-SAAAVR-TVGRPYAQEALTKYAD 977
GD D +PGI P G KTA K + ++GSL SL+ + AVR VG +AL
Sbjct: 198 GDPSDNLPGI----PGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVG-----DALRANLA 248
Query: 978 YLRRNYQVLALKRDV 1022
+ RN ++ L RDV
Sbjct: 249 SVVRNRELTDLVRDV 263
>sp|Q59156|DPO1_ANATD DNA polymerase I OS=Anaerocellum thermophilum (strain DSM
6725 / Z-1320) GN=polA PE=3 SV=2
Length = 850
Score = 87 bits (215), Expect = 2e-016
Identities = 57/206 (27%), Positives = 106/206 (51%), Gaps = 10/206 (4%)
Frame = +3
Query: 300 FLDVSPLCYEGNKPSSKAFGHWLSLFFSQVSLTDP-VIAVLDGEEGNKRRRELLPSYKAH 476
F + L N P++ +G ++++ + P +AV + G + R+ YKA+
Sbjct: 16 FFALPELTTSNNIPTNAIYG-FVNVILKYLEQEKPDYVAVAFDKRGREARKSEYEEYKAN 74
Query: 477 RKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASPD 656
RK P P + +V ++L N+P++ +G+EADDV+ +L+ Q G VI + D
Sbjct: 75 RK-PMPDNLQVQ-IPYVREILYAFNIPIIEFEGYEADDVIGSLVNQFKNTGLDIVIITGD 132
Query: 657 KDFKQLISEN--VQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVDGVPG 830
+D QL+ +N V+IV D YT+++ +Y ++ ++GD+ D +PG
Sbjct: 133 RDTLQLLDKNVVVKIVSTKFDKTVEDLYTVENVKEKYGVWANQVPDYKALVGDQSDNIPG 192
Query: 831 IQHVVPAFGRKTAMKLVRKHGSLESL 908
++ + G K+A KL+ ++ SLE +
Sbjct: 193 VKGI----GEKSAQKLLEEYSSLEEI 214
>sp|O08307|DPO1_CHLAA DNA polymerase I OS=Chloroflexus aurantiacus (strain ATCC
29366 / DSM 635 / J-10-fl) GN=polA PE=3 SV=1
Length = 942
Score = 83 bits (204), Expect = 4e-015
Identities = 62/223 (27%), Positives = 107/223 (47%), Gaps = 20/223 (8%)
Frame = +3
Query: 267 EGSRKKKRRVFFLDVSPLCYEGNKPSSKAFGHWLSLFFSQVSLT-----DPVIAVLDGEE 431
+G R F L S L +P+ FG F+Q+ LT P A + +
Sbjct: 10 DGHALAYRAFFALRESGLRSSRGEPTYAVFG------FAQILLTALAEYRPDYAAVAFDV 63
Query: 432 GNKRRRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLME 611
G R +L YKA R Y + + ++ ++ N+P+ +G+EADDV+ TL
Sbjct: 64 GRTFRDDLYAEYKAGRAETPEEFYPQ--FERIKQLVQALNIPIYTAEGYEADDVIGTLAR 121
Query: 612 QAVQRGYRAVIASPDKDFKQLISENVQIVI--PLSDLRRWSFYTLKHYHAQYN-CDPQSD 782
QA +RG +I + D D QL++++V++ + P + Y L+ +Y+ +P
Sbjct: 122 QATERGVDTIILTGDSDVLQLVNDHVRVALANPYGGKTSVTLYDLEQVRKRYDGLEPDQL 181
Query: 783 LSFRCIMGDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESLL 911
R + GD D +PG++ + G K A+ L+++ SL++LL
Sbjct: 182 ADLRGLKGDTSDNIPGVRGI----GEKGAIALLKQFRSLDALL 220
>sp|P46835|DPO1_MYCLE DNA polymerase I OS=Mycobacterium leprae GN=polA PE=3
SV=1
Length = 911
Score = 82 bits (201), Expect = 8e-015
Identities = 60/193 (31%), Positives = 95/193 (49%), Gaps = 9/193 (4%)
Frame = +3
Query: 444 RRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQ 623
R E YKA+R + P ++ + ++VL + V G EADD++ATL QA
Sbjct: 81 RSECYAGYKANRSS-IPAEFHGQ-IDITKEVLGALGITVFAEAGFEADDLIATLATQAEN 138
Query: 624 RGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIM 803
GYR ++ + D+D QL+S +V ++ P + + +T + +Y P +
Sbjct: 139 EGYRVLVVTGDRDALQLVSNDVTVLYPRKGVSELTRFTPEAVIEKYGVTPAQYPDLAALR 198
Query: 804 GDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESLLSAAAVRTVGRPYAQEALTKYADYL 983
GD D +PGI P G KTA K + +GSL+ L+ V +V R EAL + +
Sbjct: 199 GDPSDNLPGI----PGVGEKTAAKWIVDYGSLQGLVD--NVESV-RGKVGEALRTHLASV 251
Query: 984 RRNYQVLALKRDV 1022
RN ++ L +DV
Sbjct: 252 VRNRELTELVKDV 264
>sp|P43741|DPO1_HAEIN DNA polymerase I OS=Haemophilus influenzae GN=polA PE=3
SV=1
Length = 930
Score = 82 bits (200), Expect = 1e-014
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 8/170 (4%)
Frame = +3
Query: 336 KPSSKAFGHWLSLFFSQVSLTDPV-IAVLDGEEGNKRRRELLPSYKAHRKTPNPGKYSKR 512
+P+S +G L++ S +S P IAV+ +G R E+ YK+HR P P K+
Sbjct: 34 EPTSAMYG-VLNMLKSLISQVQPTHIAVVFDAKGKTFRDEMFEQYKSHR-PPMPDDLRKQ 91
Query: 513 PHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASPDKDFKQLISENVQ 692
Q + D++ +P++ ++G EADDV+ TL QA G + +I++ DKD QL+ +N+
Sbjct: 92 -IQPLHDMIRALGIPLLVVEGIEADDVIGTLALQASSLGKKVLISTGDKDMAQLVDDNIM 150
Query: 693 IVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVDGVPGIQHV 842
++ +++ S K +Y P+ + + +MGD D +PG+ V
Sbjct: 151 LINTMNN----SLLDRKGVIEKYGIPPELIIDYLALMGDSADNIPGVAGV 196
>sp|P59200|DPO1_STRR6 DNA polymerase I OS=Streptococcus pneumoniae (strain ATCC
BAA-255 / R6) GN=polA PE=3 SV=1
Length = 877
Score = 79 bits (193), Expect = 7e-014
Identities = 48/156 (30%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Frame = +3
Query: 444 RRELLPSYKAHR-KTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAV 620
R E+ YK R KTP+ + F+ ++L + L +EADD++ TL + A
Sbjct: 71 RTEMYADYKGGRAKTPDE---FREQFPFIRELLDHMGIRHYELAQYEADDIIGTLDKLAE 127
Query: 621 QRGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCI 800
Q G+ I S DKD QL E+ + I + + +T + + P + + +
Sbjct: 128 QDGFDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPAQFIDLKAL 187
Query: 801 MGDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESL 908
MGD+ D +PG+ V G KT +KL+ +HGSLE +
Sbjct: 188 MGDKSDNIPGVTKV----GEKTGIKLLLEHGSLEGI 219
>sp|P59199|DPO1_STRPN DNA polymerase I OS=Streptococcus pneumoniae GN=polA PE=3
SV=1
Length = 877
Score = 78 bits (191), Expect = 1e-013
Identities = 48/156 (30%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Frame = +3
Query: 444 RRELLPSYKAHR-KTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAV 620
R E+ YK R KTP+ + F+ ++L + L +EADD++ TL + A
Sbjct: 71 RTEMYADYKGGRAKTPDE---FREQFPFIRELLDHMGIRHYDLAQYEADDIIGTLDKLAE 127
Query: 621 QRGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCI 800
Q G+ I S DKD QL E+ + I + + +T + + P + + +
Sbjct: 128 QDGFDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPAQFIDLKAL 187
Query: 801 MGDEVDGVPGIQHVVPAFGRKTAMKLVRKHGSLESL 908
MGD+ D +PG+ V G KT +KL+ +HGSLE +
Sbjct: 188 MGDKSDNIPGVTKV----GEKTGIKLLLEHGSLEGI 219
>sp|Q9RLB6|DPO1_RICHE DNA polymerase I OS=Rickettsia helvetica GN=polA PE=3
SV=1
Length = 921
Score = 77 bits (189), Expect = 2e-013
Identities = 51/178 (28%), Positives = 76/178 (42%), Gaps = 6/178 (3%)
Frame = +3
Query: 315 PLCYEGNKPSSKAFGHWLSLFFSQVSLTDPVIAVLDGEEGNKRRRELLPSYKAHRKTPNP 494
PL +P +G L +AV+ G R + P YKA+R P
Sbjct: 25 PLTSPKGEPVGALYGFTSMLLKLLSDFKPKHVAVVFDSGGKNFRHYIYPEYKANRPPPPE 84
Query: 495 GKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASPDKDFKQL 674
+ P V DV + N P++ G+EADD++AT + G VI S DKD QL
Sbjct: 85 DLIVQLP--LVRDVASNLNFPILEKNGYEADDIIATFATKTAALGENVVIISSDKDLLQL 142
Query: 675 ISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVDGVPGIQHVVP 848
+SEN++I PL R + T ++ ++GD D +PG+ + P
Sbjct: 143 MSENIKIYDPL----RGKYITEDDVVKKFGTTSDKLREVMALIGDRSDNIPGVPSIGP 196
>sp|P74933|DPO1_TREPA DNA polymerase I OS=Treponema pallidum GN=polA PE=3 SV=2
Length = 997
Score = 77 bits (188), Expect = 3e-013
Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 7/150 (4%)
Frame = +3
Query: 459 PSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRA 638
P+YKA R + Y++ P +E++L + V+R G EADD++ATL ++
Sbjct: 75 PAYKAKRDKTSAELYAQIP--LIEEILCALGITVLRHDGFEADDLIATLAKRVAAEHCHV 132
Query: 639 VIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVD 818
VI S DKD QL+ + VQ V+ L +W+ + ++ P L +MGD D
Sbjct: 133 VIISSDKDVLQLVCDTVQ-VLRLDIDHKWTCCDAAYVQQRWTVMPTQLLDLFSLMGDSSD 191
Query: 819 GVPGIQHVVPAFGRKTAMKLVRKHGSLESL 908
VPG++ + G KTA L+ G+L+ +
Sbjct: 192 NVPGVRGI----GPKTAAHLLHCFGTLDGI 217
>sp|Q92GB7|DPO1_RICCN DNA polymerase I OS=Rickettsia conorii GN=polA PE=3 SV=1
Length = 875
Score = 77 bits (187), Expect = 3e-013
Identities = 49/178 (27%), Positives = 77/178 (43%), Gaps = 6/178 (3%)
Frame = +3
Query: 315 PLCYEGNKPSSKAFGHWLSLFFSQVSLTDPVIAVLDGEEGNKRRRELLPSYKAHRKTPNP 494
PL +P +G L +AV+ G R ++ P YKA+R P
Sbjct: 25 PLTSPKGEPVGALYGFTSMLLKLLSDFKPKHVAVVFDSGGKNFRHQIYPDYKANRPPPPE 84
Query: 495 GKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASPDKDFKQL 674
+ P V DV + N P++ G+EADD++AT + G VI S DKD QL
Sbjct: 85 DLIIQLP--LVRDVASNLNFPILEKNGYEADDIIATFATKTAALGAHVVIISSDKDLLQL 142
Query: 675 ISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVDGVPGIQHVVP 848
++EN++I PL + + T ++ ++GD D +PG+ + P
Sbjct: 143 MTENIKIYDPL----KGKYITEDDVVKKFGTTSDKLREVMALIGDRSDNIPGVPSIGP 196
>sp|Q1RH76|DPO1_RICBR DNA polymerase I OS=Rickettsia bellii (strain RML369-C)
GN=polA PE=3 SV=1
Length = 871
Score = 75 bits (184), Expect = 7e-013
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 8/179 (4%)
Frame = +3
Query: 315 PLCYEGNKPSSKAFGHWLSLFFSQVSLTDPVIAVLDGEEGNKR-RRELLPSYKAHRKTPN 491
PL +P +G + S+ ++ P A + + G K R E+ P YKA+R P
Sbjct: 25 PLTSPKGEPVGALYG-FTSMLLKLLNDFKPKHAAVVFDSGGKNFRHEIYPEYKANRPPPP 83
Query: 492 PGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASPDKDFKQ 671
++ P V DV N P++ G EADD++AT + G V+ S DKD Q
Sbjct: 84 EDLIAQLP--LVRDVARNLNFPILEKNGFEADDIIATFAAKTASIGEEVVVISSDKDLLQ 141
Query: 672 LISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVDGVPGIQHVVP 848
L+++NV+I PL + + T + ++ ++GD+ D +PG+ + P
Sbjct: 142 LMNDNVKIYDPL----KAKYITEDNVVEKFGVTSDKLREVMALIGDKSDNIPGVPSIGP 196
>sp|Q9RAA9|DPO1_RICFE DNA polymerase I OS=Rickettsia felis GN=polA PE=3 SV=1
Length = 922
Score = 74 bits (181), Expect = 2e-012
Identities = 50/179 (27%), Positives = 80/179 (44%), Gaps = 8/179 (4%)
Frame = +3
Query: 315 PLCYEGNKPSSKAFGHWLSLFFSQVSLTDPV-IAVLDGEEGNKRRRELLPSYKAHRKTPN 491
PL +P +G + S+ +S P +AV+ G R + P YKA+R P
Sbjct: 25 PLTSPKGEPVGALYG-FASMLLKLLSDFKPKHVAVVFDSGGKNFRHHIYPEYKANRPPPP 83
Query: 492 PGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASPDKDFKQ 671
+ P V DV + N P++ G+EADD++AT + G V+ S DKD Q
Sbjct: 84 EDLVVQLP--LVRDVASNLNFPILEKNGYEADDIIATFAAKTAALGEDVVVISSDKDLLQ 141
Query: 672 LISENVQIVIPLSDLRRWSFYTLKHYHAQYNCDPQSDLSFRCIMGDEVDGVPGIQHVVP 848
L+ EN++I PL + + T ++ ++GD D +PG+ + P
Sbjct: 142 LMGENIKIYDPL----KGKYITEDDVVKKFGTTSDKLREVMALIGDRSDNIPGVPSIGP 196
>sp|Q9RLA0|DPO1_RICTY DNA polymerase I OS=Rickettsia typhi GN=polA PE=3 SV=1
Length = 872
Score = 74 bits (179), Expect = 3e-012
Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 6/146 (4%)
Frame = +3
Query: 411 AVLDGEEGNKRRRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEADD 590
A++ G R ++ +YKA+R TP + P + DV + N ++ G+EADD
Sbjct: 57 AIVFDSGGKNFRHKIYQNYKANRPTPPEDLIGQLP--LIRDVASHLNFAILEKNGYEADD 114
Query: 591 VVATLMEQAVQRGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNCD 770
++AT + + G +I S DKD QL+S+N++I P+ + + T ++
Sbjct: 115 IIATFATKTITLGKEVIIISSDKDLLQLMSKNIKIYDPI----KCKYITEDDVIIKFGTT 170
Query: 771 PQSDLSFRCIMGDEVDGVPGIQHVVP 848
P ++GD D +PG+ + P
Sbjct: 171 PDKLREVMALIGDRSDNIPGVPSIGP 196
>sp|O51498|DPO1_BORBU DNA polymerase I OS=Borrelia burgdorferi GN=polA PE=3
SV=1
Length = 908
Score = 73 bits (177), Expect = 5e-012
Identities = 51/188 (27%), Positives = 93/188 (49%), Gaps = 12/188 (6%)
Frame = +3
Query: 357 GHWLSLFFSQVSLTDPVIAVLDGEEGNKRRRELLPSYKAHRKTPNPGKYSKRPHQFVEDV 536
G + +LFF + + E R++ PSYKA R P + ++++
Sbjct: 38 GFFKTLFFIIKEKNPEHLIITFDSEVPTFRKQKYPSYKATRDLPPDDLIPQ--IGWIKEG 95
Query: 537 LTKCNVPVVRLQGHEADDVVATLMEQAVQRGYRAVIASPDKDFKQLISENVQIVIPLSDL 716
L K +P+ ++G+EADD++A+ ++A + Y I SPDKD Q +SE V+I+ +
Sbjct: 96 LLKAKIPIFEMEGYEADDLLASFAKKAAKNNYLTYIISPDKDLLQTMSEYVKIL----KI 151
Query: 717 RRWSFYTLKHYHA--QYNCDPQSDLSFRCIMGDEVDGVPGIQHVVPAFGRKTAMKLVRKH 890
SF + + + ++ + + I+GD D +PGI+ + G K A L+R+
Sbjct: 152 ENNSFIEMDNEYVTKKFGVNSFQIKDYLAIVGDRSDNIPGIKGI----GAKGAANLLREF 207
Query: 891 GSLESLLS 914
+L+ + S
Sbjct: 208 KTLDGIYS 215
>sp|O05949|DPO1_RICPR DNA polymerase I OS=Rickettsia prowazekii GN=polA PE=3
SV=1
Length = 867
Score = 73 bits (177), Expect = 5e-012
Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 6/147 (4%)
Frame = +3
Query: 408 IAVLDGEEGNKRRRELLPSYKAHRKTPNPGKYSKRPHQFVEDVLTKCNVPVVRLQGHEAD 587
+A++ G R ++ +YKA+R P ++ P V DV + ++ G+EAD
Sbjct: 56 VAIVFDSGGKNFRHKIYQNYKANRPLPPKDLIAQLP--LVRDVASNFKFAILEKNGYEAD 113
Query: 588 DVVATLMEQAVQRGYRAVIASPDKDFKQLISENVQIVIPLSDLRRWSFYTLKHYHAQYNC 767
D++AT + V G +I S DKD QL+S+N++I P+ + + T + ++
Sbjct: 114 DIIATFATKTVSLGEEVIIISSDKDLLQLMSKNIKIYDPI----KCKYITEDNVVTKFGT 169
Query: 768 DPQSDLSFRCIMGDEVDGVPGIQHVVP 848
P ++GD D +PG+ + P
Sbjct: 170 TPDKLREVMALIGDRSDNIPGVPSIGP 196
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,819,846,109
Number of Sequences: 518415
Number of Extensions: 95819846109
Number of Successful Extensions: 619733697
Number of sequences better than 0.0: 0
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